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Dennis M Abraham

Assistant Professor of Medicine
Medicine, Cardiology
213 Research Drive; CARL Building, Box 102154, Durham, NC 27710
Dept of Medicine, Box 102154, Durham, NC 27710

Current Appointments & Affiliations


Assistant Professor of Medicine · 2021 - Present Medicine, Cardiology, Medicine

Recent Publications


Fibroblast growth factor 23 and fibroblast growth factor receptor 4 promote cardiac metabolic remodeling in chronic kidney disease.

Journal Article Kidney Int · February 7, 2025 Chronic kidney disease (CKD) is a global health epidemic that greatly increases mortality due to cardiovascular disease. Left ventricular hypertrophy (LVH) is an important mechanism of cardiac injury in CKD. High serum levels of fibroblast growth factor (F ... Full text Link to item Cite

USP20 deletion promotes eccentric cardiac remodeling in response to pressure overload and increases mortality.

Journal Article Am J Physiol Heart Circ Physiol · November 1, 2024 Left ventricular hypertrophy (LVH) caused by chronic pressure overload with subsequent pathological remodeling is a major cardiovascular risk factor for heart failure and mortality. The role of deubiquitinases in LVH has not been well characterized. To def ... Full text Link to item Cite

Late onset cardiovascular dysfunction in adult mice resulting from galactic cosmic ray exposure.

Journal Article iScience · April 15, 2022 The complex and inaccessible space radiation environment poses an unresolved risk to astronaut cardiovascular health during long-term space exploration missions. To model this risk, healthy male c57BL/6 mice aged six months (corresponding to an astronaut o ... Full text Link to item Cite
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Recent Grants


Regulation of myocardial GPCRs by USP20 in normal and hypertrophied heart

ResearchCollaborating Investigator · Awarded by National Institutes of Health · 2021 - 2025

Proteomic Signatures of Space Radiation Induced Cardiovascular Degeneration

ResearchCollaborator · Awarded by National Aeronautics and Space Administration · 2016 - 2022

TREK-1 in fibroblast differentiation and cardiac fibrosis development

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2015 - 2020

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Education, Training & Certifications


Thomas Jefferson University · 2002 M.D.