Derek Southwell | Scholars@Duke

Derek Southwell
Assistant Professor of Neurosurgery

Current Appointments & Affiliations

Assistant Professor of Neurosurgery, Neurosurgery, Neurosurgery 2018
Assistant Research Professor in Neurobiology, Neurobiology, Basic Science Departments 2018
Faculty Network Member of the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2019

Contact Information

DUMC 3807, Durham, NC 27710
DUMC 3807, 1542 Blue Zone Duke South, Durham, NC 27710
derek.southwell@duke.edu (919) 660-3928

Background
Education, Training, & Certifications
- Residency, Neurosurgery, University of California - San Francisco 2013 - 2018
- Residency, Neurosurgery, Stanford University School of Medicine 2011 - 2013
- M.D., University of California - San Francisco 2011
- Ph.D., University of California - San Francisco 2009
- B.S., Massachusetts Institute of Technology 2001
Recognition
Awards & Honors
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Southwell, DG, Breshears, JD, Lyon, WR, and McDermott, MW. "A Method for Cranial Nerve XI Silencing During Surgery of the Foramen Magnum Region: Technical Case Report." Operative Neurosurgery (Hagerstown, Md.) 16, no. 4 (April 2019): E130-E133. Full Text
  - Southwell, DG, Breshears, JD, Lyon, WR, and McDermott, MW. "In Reply: A Method for Cranial Nerve XI Silencing During Surgery of the Foramen Magnum Region: Technical Case Report." Operative Neurosurgery (Hagerstown, Md.) 16, no. 1 (January 2019): E36-null. Full Text
  - Breshears, JD, Southwell, DG, and Chang, EF. "Inhibition of Manual Movements at Speech Arrest Sites in the Posterior Inferior Frontal Lobe." Neurosurgery (December 12, 2018). Full Text
  - Southwell, DG, Birk, HS, Han, SJ, Li, J, Sall, JW, and Berger, MS. "Resection of gliomas deemed inoperable by neurosurgeons based on preoperative imaging studies." Journal of Neurosurgery 129, no. 3 (September 2018): 567-575. Full Text
  - Southwell, DG, Birk, HS, Larson, PS, Starr, PA, Sugrue, LP, and Auguste, KI. "Laser ablative therapy of sessile hypothalamic hamartomas in children using interventional MRI: report of 5 cases." Journal of Neurosurgery. Pediatrics 21, no. 5 (May 2018): 460-465. Full Text
  - Rutkowski, MJ, Alward, RM, Chen, R, Wagner, J, Jahangiri, A, Southwell, DG, Kunwar, S, Blevins, L, Lee, H, and Aghi, MK. "Atypical pituitary adenoma: a clinicopathologic case series." Journal of Neurosurgery 128, no. 4 (April 2018): 1058-1065. Full Text
  - Southwell, DG, Rutkowski, MJ, San Luciano, M, Racine, C, Ostrem, J, Starr, PA, and Larson, PS. "Before and after the veterans affairs cooperative program 468 study: Deep brain stimulator target selection for treatment of Parkinson's disease." Parkinsonism & Related Disorders 48 (March 2018): 40-44. Full Text
  - Southwell, DG, Riva, M, Jordan, K, Caverzasi, E, Li, J, Perry, DW, Henry, RG, and Berger, MS. "Language outcomes after resection of dominant inferior parietal lobule gliomas." Journal of Neurosurgery 127, no. 4 (October 2017): 781-789. Full Text
  - Southwell, DG, Osorio, JA, Liverman, CS, Friedman, LM, Naidu, RK, Poree, LR, Henry, MM, and Jacques, L. "Intrathecal catheter-associated inflammatory mass in a neurofibromatosis type-1 patient receiving fentanyl and bupivacaine." Surgical Neurology International 8 (January 2017): 159-null. Full Text
  - Southwell, DG, Hervey-Jumper, SL, Perry, DW, and Berger, MS. "Intraoperative mapping during repeat awake craniotomy reveals the functional plasticity of adult cortex." Journal of Neurosurgery 124, no. 5 (May 2016): 1460-1469. Full Text
  - Southwell, DG, Narvid, JA, Martin, AJ, Qasim, SE, Starr, PA, and Larson, PS. "Comparison of Deep Brain Stimulation Lead Targeting Accuracy and Procedure Duration between 1.5- and 3-Tesla Interventional Magnetic Resonance Imaging Systems: An Initial 12-Month Experience." Stereotactic and Functional Neurosurgery 94, no. 2 (January 2016): 102-107. Full Text
  - Southwell, DG, Nicholas, CR, Basbaum, AI, Stryker, MP, Kriegstein, AR, Rubenstein, JL, and Alvarez-Buylla, A. "Interneurons from embryonic development to cell-based therapy." Science (New York, N.Y.) 344, no. 6180 (April 2014): 1240622-null. (Review) Full Text
  - Nicholas, CR, Chen, J, Tang, Y, Southwell, DG, Chalmers, N, Vogt, D, Arnold, CM, Chen, Y-JJ, Stanley, EG, Elefanty, AG, Sasai, Y, Alvarez-Buylla, A, Rubenstein, JLR, and Kriegstein, AR. "Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development." Cell Stem Cell 12, no. 5 (May 2013): 573-586. Full Text
  - Southwell, DG, Paredes, MF, Galvao, RP, Jones, DL, Froemke, RC, Sebe, JY, Alfaro-Cervello, C, Tang, Y, Garcia-Verdugo, JM, Rubenstein, JL, Baraban, SC, and Alvarez-Buylla, A. "Intrinsically determined cell death of developing cortical interneurons." Nature 491, no. 7422 (November 2012): 109-113. Full Text
  - Southwell, DG, Garcia, PA, Berger, MS, Barbaro, NM, and Chang, EF. "Long-term seizure control outcomes after resection of gangliogliomas." Neurosurgery 70, no. 6 (June 2012): 1406-1413. Full Text
  - Southwell, DG, Froemke, RC, Alvarez-Buylla, A, Stryker, MP, and Gandhi, SP. "Cortical plasticity induced by inhibitory neuron transplantation." Science (New York, N.Y.) 327, no. 5969 (February 2010): 1145-1148. Full Text
  - Baraban, SC, Southwell, DG, Estrada, RC, Jones, DL, Sebe, JY, Alfaro-Cervello, C, García-Verdugo, JM, Rubenstein, JLR, and Alvarez-Buylla, A. "Reduction of seizures by transplantation of cortical GABAergic interneuron precursors into Kv1.1 mutant mice." Proceedings of the National Academy of Sciences of the United States of America 106, no. 36 (September 2009): 15472-15477. Full Text
  - Alvarez-Dolado, M, Calcagnotto, ME, Karkar, KM, Southwell, DG, Jones-Davis, DM, Estrada, RC, Rubenstein, JLR, Alvarez-Buylla, A, and Baraban, SC. "Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain." The Journal of Neuroscience : the Official Journal of the Society for Neuroscience 26, no. 28 (July 2006): 7380-7389. Full Text
  - Southwell, DG, Bechtold, JE, Lew, WD, and Schmidt, AH. "Improving the detection of acetabular osteolysis using oblique radiographs." The Journal of Bone and Joint Surgery. British Volume 81, no. 2 (March 1999): 289-295. Full Text

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Education, Training, & Certifications

Awards & Honors

Selected Publications

Academic Articles