Scholars@Duke
Divya Natesan

Divya Natesan

Assistant Professor of Radiation Oncology
Radiation Oncology
divya.natesan@duke.edu
3404 Wake Forest Rd, Lower LVL,, Raleigh, NC 27609
3404 Wake Forest Rd, Lower LVL,, Raleigh, NC 27609

Selected Publications

Researcher Experience and Comfort With Telemedicine and Remote Patient Monitoring in Cancer Treatment Trials.

Conference Oncologist · April 4, 2024 BACKGROUND: Since the onset of COVID-19, oncology practices across the US have integrated telemedicine (TM) and remote patient monitoring (RPM) into routine care and clinical trials. The extent of provider experience and comfort with TM/RPM in treatment tr ... Full text Link to item Cite

Health Care Cost Reductions with Machine Learning-Directed Evaluations during Radiation Therapy - An Economic Analysis of a Randomized Controlled Study.

Journal Article NEJM AI · April 2024 BACKGROUND: Machine learning (ML) may cost-effectively direct health care by identifying patients most likely to benefit from preventative interventions to avoid negative and expensive outcomes. System for High-Intensity Evaluation During Radiation Therapy ... Full text Link to item Cite

Low contralateral neck recurrence risk with ipsilateral neck radiotherapy in N2b tonsillar squamous cell carcinoma.

Journal Article Oral Oncol · April 2023 OBJECTIVES: To characterize factors including nodal burden, pre-treatment imaging, and other patient factors which may influence the role of ipsilateral neck radiotherapy (IRT) in tonsillar squamous cell carcinoma (SCC) with multiple involved ipsilateral n ... Full text Link to item Cite

Clinical Factors Associated With 30-Day Mortality Among Patients Undergoing Radiation Therapy for Brain Metastases.

Journal Article Adv Radiat Oncol · 2023 PURPOSE: Existing brain metastasis prognostic models do not identify patients at risk of very poor survival after radiation therapy (RT). Identifying patient and disease risk factors for 30-day mortality (30-DM) after RT may help identify patients who woul ... Full text Link to item Cite

Toxicity and Outcomes of Moderately Hypofractionated Radiation for Prostate Cancer With Seminal Vesicle Involvement.

Journal Article Adv Radiat Oncol · 2023 PURPOSE: The aim of this study was to assess the toxicity and outcomes following treatment of prostate cancer with seminal vesicle involvement (SVI) evident on magnetic resonance imaging or clinical examination with moderately hypofractionated radiation th ... Full text Link to item Cite

Prognostic Model for Intracranial Progression after Stereotactic Radiosurgery: A Multicenter Validation Study.

Journal Article Cancers (Basel) · October 22, 2022 Stereotactic radiosurgery (SRS) is a standard of care for many patients with brain metastases. To optimize post-SRS surveillance, this study aimed to validate a previously published nomogram predicting post-SRS intracranial progression (IP). We identified ... Full text Link to item Cite

Impact of Race on Outcomes of High-Risk Patients With Prostate Cancer Treated With Moderately Hypofractionated Radiotherapy in an Equal Access Setting.

Journal Article Fed Pract · August 2022 BACKGROUND: Moderately hypofractionated radiotherapy (MHRT) is an accepted treatment for localized prostate cancer; however, limited MHRT data address high-risk prostate cancer (HRPC) and/or African American patients. We report clinical outcomes and toxici ... Full text Link to item Cite

Does Prophylactic Paraortic Lymph Node Irradiation Improve Outcomes in Women With Stage IIIC1 Endometrial Carcinoma?

Journal Article Pract Radiat Oncol · 2022 PURPOSE: To evaluate the impact of prophylactic paraortic lymph node (PALN) radiation therapy (RT) on clinical outcomes in patients with International Federation of Obstetrics and Gynecology 2018 stage IIIC1 endometrial cancer (EC). METHODS AND MATERIALS: ... Full text Link to item Cite

Effect of Large Prostate Volume on Efficacy and Toxicity of Moderately Hypofractionated Radiation Therapy in Patients With Prostate Cancer.

Journal Article Adv Radiat Oncol · 2022 PURPOSE: To evaluate the effect of prostate volume on outcomes after moderately hypofractionated radiation therapy (mHFRT) for prostate cancer. METHODS AND MATERIALS: Prostate cancer patients treated with mHFRT at a Veteran's Affairs Medical Center from Au ... Full text Link to item Cite

Machine Learning Algorithm Prospectively Predicts Survival for High-Risk Patients Undergoing Radiotherapy: A Survival Analysis of SHIELD-RT.

Conference International journal of radiation oncology, biology, physics · November 2021 Purpose/objective(s)Mortality prediction is critical to appropriate cancer care planning. This has become a topic of interest, with machine learning (ML) tools demonstrating accurate binary predictions for mortality at specific time points. There ... Full text Cite

Radiation Oncology Provider Telehealth Satisfaction: Survey Results From a Single NCI-Designated Institution.

Conference International journal of radiation oncology, biology, physics · November 2021 Purpose/objective(s)Telehealth (TH) for radiation oncology services has emerged as a new modality for care delivery and will likely persist beyond the COVID pandemic. Data regarding radiation oncology provider satisfaction of TH are limited and es ... Full text Cite

Impact of Target Volume and Image Guidance on Post-Prostatectomy Patients Treated With Intensity Modulated Radiation Therapy.

Conference International journal of radiation oncology, biology, physics · November 2021 Purpose/objective(s)Post-operative radiotherapy (PORT) is utilized in select prostate cancer patients. IMRT has been associated with improved dosimetry and acute toxicity. Smaller treatment margins for PORT have been recommended when using image g ... Full text Cite

A Multi-Institutional Analysis of Adjuvant Chemotherapy and Radiation Sequence in Women With Stage IIIC Endometrial Cancer.

Journal Article Int J Radiat Oncol Biol Phys · August 1, 2021 PURPOSE: Our purpose was to evaluate the effect of sequence and type of adjuvant therapy for patients with stage IIIC endometrial carcinoma (EC) on outcomes. METHODS AND MATERIALS: In a multi-institutional retrospective cohort study, patients with stage II ... Full text Link to item Cite

Association of human papilloma virus status and response to radiotherapy in vulvar squamous cell carcinoma.

Journal Article Int J Gynecol Cancer · January 2020 INTRODUCTION: Vulvar squamous cell carcinoma develops through two separate pathways, associated with the presence or absence of high-risk human papilloma virus (HPV). The objective of this study was to evaluate treatment response and clinical outcomes in w ... Full text Link to item Cite

Primary Versus Preoperative Radiation for Locally Advanced Vulvar Cancer.

Journal Article Int J Gynecol Cancer · May 2017 OBJECTIVES: The objective of this study was to evaluate patterns of care and the survival impact of primary radiation and preoperative radiation therapy with surgery in women with locally advanced vulvar cancer using a large national cohort. METHODS AND MA ... Full text Link to item Cite

Gestational Exposure to Air Pollution Alters Cortical Volume, Microglial Morphology, and Microglia-Neuron Interactions in a Sex-Specific Manner.

Journal Article Front Synaptic Neurosci · 2017 Microglia are the resident immune cells of the brain, important for normal neural development in addition to host defense in response to inflammatory stimuli. Air pollution is one of the most pervasive and harmful environmental toxicants in the modern worl ... Full text Link to item Cite

Definitive Chemoradiotherapy for Vulvar Cancer.

Journal Article Int J Gynecol Cancer · November 2016 OBJECTIVES: This study aimed to evaluate clinical outcomes after chemoradiation (CRT) for the definitive (nonsurgical) treatment of vulvar cancer. MATERIALS AND METHODS: Women with vulvar cancer treated with definitive CRT at a single academic institution ... Full text Link to item Cite