David Stuart Millington
Professor Emeritus of Pediatrics

Development of new mass spectrometric methods for the analysis of disease-specific metabolites in human physiological fluids for application to the diagnosis of inborn errors of metabolism. The development of automated methods based on tandem mass spectrometry for the analysis of these metabolites in blood spots and urine from neonates, with a view to revolutionizing newborn screening methodology.
Development and application of mass spectrometry based biomarker assays for monitoring treatment and diagnosis of lysosomal storage diseases (LSDs).
Development and application of methods for analysis of drugs used in human clinical trials.
Application of "lab-on-a-chip" technology, based on digital microfluidics, to enzymatic and DNA- based assays used in newborn screening and at the point of care.
Development and application of new methods for studing clucose metabolism both in vivo and in vitro using stable isotope labeling with tandem mass spectrometry.
Development and application of methods for the analysis of urine markers of oxidative stress, using tandem mass spectrometry.

Current Appointments & Affiliations

Contact Information

  • 801-6 Capitola Drive, Box 103856, Durham, NC 27713
  • Box 3028 Med Ctr, Durham, NC 27710

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.