Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellow in Cardiology, Medicine, Duke University 2003 - 2007
  • Chief Resident in Medicine (DUMC), Medicine, Duke University 2002 - 2003
  • Medical Resident, Medicine, Duke University 1999 - 2002
  • M.D., University of Florida 1999
• 

  Duke Appointment History

  • Assistant Professor of Medicine, Medicine, Cardiology, Medicine 2014 - 2018
  • Assistant Professor of Medicine, Medicine, Cardiology, Medicine 2012 - 2014
  • Medical Instructor in the Department of Medicine, Medicine, Cardiology, Medicine 2007 - 2012
  • Instructor, Temporary in the Department of Medicine, Medicine, Cardiology, Medicine 2007
  • Associate in the Department of Medicine, Medicine, General Internal Medicine, Medicine 2002 - 2003
• Research
• 

  Selected Grants

  • Delayed-Enhancement Cardiac MRI: Prognostic Implications and Improved Imaging awarded by National Institutes of Health 2010 - 2015
• 

  External Relationships

  • Medtronic
  • Philips
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Lewis, Robert K., Sean D. Pokorney, Donald D. Hegland, and Jonathan P. Piccini. “Hands on: How to approach patients undergoing lead extraction.” J Cardiovasc Electrophysiol 31, no. 7 (July 2020): 1801–8. https://doi.org/10.1111/jce.14244.
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    • Black-Maier, Eric, Michael Rehorn, Rahul Loungani, Daniel J. Friedman, Fawaz Alenezi, Kyle Geurink, Sean D. Pokorney, et al. “Catheter ablation of atrial fibrillation in cardiac amyloidosis.” Pacing Clin Electrophysiol, June 23, 2020. https://doi.org/10.1111/pace.13992.
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    • Black-Maier, Eric, Jonathan P. Piccini, Muath Bishawi, Sean D. Pokorney, Benjamin Bryner, Jacob N. Schroder, Vance G. Fowler, et al. “Lead Extraction for Cardiovascular Implantable Electronic Device Infection in Patients With Left Ventricular Assist Devices.” Jacc Clin Electrophysiol 6, no. 6 (June 2020): 672–80. https://doi.org/10.1016/j.jacep.2020.02.006.
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    • Black-Maier, Eric, Benjamin A. Steinberg, Kevin M. Trulock, Frances Wang, Yuliya Lokhnygina, Wanda O’Neal, Sana Al-Khatib, et al. “Effectiveness of catheter ablation of atrial fibrillation according to heart failure etiology.” J Arrhythm 36, no. 1 (February 2020): 84–92. https://doi.org/10.1002/joa3.12291.
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    • Sutter, Joanne S., Yuliya Lokhnygina, James P. Daubert, Tristram Bahnson, Kevin Jackson, Jason I. Koontz, Albert Y. Sun, et al. “Safety and efficacy outcomes of left atrial posterior wall isolation compared to pulmonary vein isolation and pulmonary vein isolation with linear ablation for the treatment of persistent atrial fibrillation.” Am Heart J 220 (February 2020): 89–96. https://doi.org/10.1016/j.ahj.2019.11.010.
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    • Black-Maier, Eric, Alice Parish, Benjamin A. Steinberg, Cynthia L. Green, Zak Loring, Adam S. Barnett, Sana M. Al-Khatib, et al. “Predicting atrial fibrillation recurrence after ablation in patients with heart failure: Validity of the APPLE and CAAP-AF risk scoring systems.” Pacing Clin Electrophysiol 42, no. 11 (November 2019): 1440–47. https://doi.org/10.1111/pace.13805.
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    • Gaeta, Stephen, Jacob N. Schroder, Mani A. Daneshmand, Kevin L. Thomas, Donald D. Hegland, Jonathan P. Piccini, James P. Daubert, Jason I. Koontz, and Albert Y. Sun. “Catheter Ablation of Mid-Myocardial Ventricular Tachycardia by Simultaneous Unipolar Radiofrequency Ablation With Half-Normal Saline Irrigation.” Jacc Clin Electrophysiol 4, no. 9 (September 2018): 1263–64. https://doi.org/10.1016/j.jacep.2018.05.004.
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    • Black-Maier, Eric, Xinru Ren, Benjamin A. Steinberg, Cynthia L. Green, Adam S. Barnett, Normita Sta Rosa, Sana M. Al-Khatib, et al. “Catheter ablation of atrial fibrillation in patients with heart failure and preserved ejection fraction.” Heart Rhythm 15, no. 5 (May 2018): 651–57. https://doi.org/10.1016/j.hrthm.2017.12.001.
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    • Pokorney, Sean D., Xiaojuan Mi, Robert K. Lewis, Melissa Greiner, Laurence M. Epstein, Roger G. Carrillo, Emily P. Zeitler, Sana M. Al-Khatib, Donald D. Hegland, and Jonathan P. Piccini. “Outcomes Associated With Extraction Versus Capping and Abandoning Pacing and Defibrillator Leads.” Circulation 136, no. 15 (October 10, 2017): 1387–95. https://doi.org/10.1161/CIRCULATIONAHA.117.027636.
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    • Pokorney, Sean D., Craig S. Parzynski, James P. Daubert, Donald D. Hegland, Paul D. Varosy, Jeptha P. Curtis, and Sana M. Al-Khatib. “Temporal Trends in and Factors Associated With Use of Single- Versus Dual-Coil Implantable Cardioverter-Defibrillator Leads: Data From the NCDR ICD Registry.” Jacc Clin Electrophysiol 3, no. 6 (June 2017): 612–19. https://doi.org/10.1016/j.jacep.2016.11.014.
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    • Boggan, Joel C., Arthur W. Baker, Sarah S. Lewis, Kristen V. Dicks, Michael J. Durkin, Rebekah W. Moehring, Luke F. Chen, Lauren P. Knelson, Donald D. Hegland, and Deverick J. Anderson. “An Automated Surveillance Strategy to Identify Infectious Complications After Cardiac Implantable Electronic Device Procedures.” Open Forum Infect Dis 2, no. 4 (December 2015): ofv128. https://doi.org/10.1093/ofid/ofv128.
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    • Holmqvist, Fredrik, Kevin L. Thomas, Samuel Broderick, Mads Ersbøll, Devinder Singh, Karen Chiswell, Linda K. Shaw, Donald D. Hegland, Eric J. Velazquez, and James P. Daubert. “Clinical outcome as a function of the PR-interval-there is virtue in moderation: data from the Duke Databank for cardiovascular disease.” Europace 17, no. 6 (June 2015): 978–85. https://doi.org/10.1093/europace/euu211.
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    • Krishnamoorthy, Arun, Sean D. Pokorney, Robert K. Lewis, James P. Daubert, Ruth A. Greenfield, Donald D. Hegland, Carmelo A. Milano, et al. “Cardiac implantable electronic device removal in patients with left ventricular assist device associated infections.” J Cardiovasc Electrophysiol 25, no. 11 (November 2014): 1199–1205. https://doi.org/10.1111/jce.12461.
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    • Lewis, Robert K., Sean D. Pokorney, Ruth Ann Greenfield, Patrick M. Hranitzky, Donald D. Hegland, Jacob N. Schroder, Shu S. Lin, et al. “Preprocedural ECG-gated computed tomography for prevention of complications during lead extraction.” Pacing Clin Electrophysiol 37, no. 10 (October 2014): 1297–1305. https://doi.org/10.1111/pace.12485.
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    • Piccini, Jonathan P., Yue Zhao, Benjamin A. Steinberg, Xia He, Joseph P. Mathew, David A. Fullerton, Donald D. Hegland, et al. “Comparative effectiveness of pharmacotherapies for prevention of atrial fibrillation following coronary artery bypass surgery.” Am J Cardiol 112, no. 7 (October 1, 2013): 954–60. https://doi.org/10.1016/j.amjcard.2013.05.029.
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    • Hess, Paul L., Xiaojuan Mi, Lesley H. Curtis, Bruce L. Wilkoff, Donald D. Hegland, and Sana M. Al-Khatib. “Follow-up of patients with new cardiovascular implantable electronic devices: is adherence to the experts' recommendations associated with improved outcomes?” Heart Rhythm 10, no. 8 (August 2013): 1127–33. https://doi.org/10.1016/j.hrthm.2013.06.009.
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    • Jackson, Kevin P., Donald D. Hegland, Camille Frazier-Mills, Jonathan P. Piccini, Jason I. Koontz, Brett D. Atwater, James P. Daubert, and Seth J. Worley. “Impact of using a telescoping-support catheter system for left ventricular lead placement on implant success and procedure time of cardiac resynchronization therapy.” Pacing Clin Electrophysiol 36, no. 5 (May 2013): 553–58. https://doi.org/10.1111/pace.12103.
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    • Klem, Igor, Jonathan W. Weinsaft, Tristram D. Bahnson, Don Hegland, Han W. Kim, Brenda Hayes, Michele A. Parker, Robert M. Judd, and Raymond J. Kim. “Assessment of myocardial scarring improves risk stratification in patients evaluated for cardiac defibrillator implantation.” J Am Coll Cardiol 60, no. 5 (July 31, 2012): 408–20. https://doi.org/10.1016/j.jacc.2012.02.070.
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    • Hegland, Donald, Jonathan P. Piccini, Larry B. Goldstein, and James P. Daubert. “Cerebral magnetic resonance findings in asymptomatic patients after atrial fibrillation catheter ablation: cause for alarm or further study?” J Cardiovasc Electrophysiol 22, no. 9 (September 2011): 969–72. https://doi.org/10.1111/j.1540-8167.2011.02093.x.
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    • Atwater, Brett D., Thomas W. Wallace, Han W. Kim, Patrick M. Hranitzky, Tristram D. Bahnson, Donald D. Hegland, and James P. Daubert. “Pulmonary vein contraction before and after radiofrequency ablation for atrial fibrillation.” J Cardiovasc Electrophysiol 22, no. 2 (February 2011): 169–74. https://doi.org/10.1111/j.1540-8167.2010.01868.x.
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    • Mackensen, G Burkhard, Donald Hegland, Danny Rivera, David B. Adams, and Tristram D. Bahnson. “Real-time 3-dimensional transesophageal echocardiography during left atrial radiofrequency catheter ablation for atrial fibrillation.” Circ Cardiovasc Imaging 1, no. 1 (July 2008): 85–86. https://doi.org/10.1161/CIRCIMAGING.107.763128.
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    • Hegland, Donald D., Geoffrey A. Kunz, J Kevin Harrison, and Andrew Wang. “Clinical problem-solving. A hole in the argument.” N Engl J Med 353, no. 22 (December 1, 2005): 2385–90. https://doi.org/10.1056/NEJMcps050473.
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    • Hegland, D. D., D. M. Sullivan, I. I. Rovira, A. Li, I. Kovesdi, J. T. Bruder, and T. Finkel. “Regulation of endothelial cell adherens junctions by a Ras-dependent signal transduction pathway.” Biochem Biophys Res Commun 260, no. 2 (July 5, 1999): 371–76. https://doi.org/10.1006/bbrc.1999.0919.
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    • Doanes, A. M., D. D. Hegland, R. Sethi, I. Kovesdi, J. T. Bruder, and T. Finkel. “VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases.” Biochem Biophys Res Commun 255, no. 2 (February 16, 1999): 545–48. https://doi.org/10.1006/bbrc.1999.0227.
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    • Pracyk, J. B., K. Tanaka, D. D. Hegland, K. S. Kim, R. Sethi, I. I. Rovira, D. R. Blazina, et al. “A requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy.” J Clin Invest 102, no. 5 (September 1, 1998): 929–37. https://doi.org/10.1172/JCI2552.
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    • Pracyk, J. B., D. D. Hegland, and K. Tanaka. “Effect of a dominant negative ras on myocardial hypertrophy by using adenoviral-mediated gene transfer.” Surgery 122, no. 2 (August 1997): 404–10. https://doi.org/10.1016/s0039-6060(97)90033-7.
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