Current Appointments & Affiliations
Assistant Professor of Pathology
·
2022 - Present
Pathology,
Clinical Science Departments
Associate Dean for Basic Science in the School of Medicine
·
2023 - Present
Pathology,
Clinical Science Departments
Executive Team Member of Duke Center for Applied Genomics and Precision Medicine
·
2014 - Present
The Precision Medicine Program,
Medicine
Recent Publications
New Genetic Approaches to AD: Lessons from APOE-TOMM40 Phylogenetics.
Journal Article Curr Neurol Neurosci Rep · May 2016 Clinical trials for Alzheimer's disease are now focusing on the earliest stages of the disease with the goal of delaying dementia onset. There is great utility in using genetic variants to identify individuals at high age-dependent risk when the goal is to ... Full text Link to item CiteEffects of low doses of pioglitazone on resting-state functional connectivity in conscious rat brain.
Journal Article PLoS One · 2015 Pioglitazone (PIO) is a peroxisome proliferator-activated receptor-γ (PPARγ) agonist in clinical use for treatment of type 2 diabetes (T2DM). Accumulating evidence suggests PPARγ agonists may be useful for treating or delaying the onset of Alzheimer's dise ... Full text Link to item CiteA Pharmacogenetics Supported Clinical Trial to Delay Onset of Mild Cognitive Impairment due to Alzheimer's Disease Using Low Dose Pioglitazone: The Tommorrow Study
Conference NEUROPSYCHOPHARMACOLOGY · December 1, 2014 Link to item CiteEducation, Training & Certifications
University of North Carolina, Chapel Hill ·
2013
M.H.A.
Duke University, School of Medicine ·
1993
Ph.D.