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Douglas Wixted

Research Program Leader, Sr
Duke Clinical & Translational Science Institute
701 W Main St, Suite 500, Durham, NC 27701

Selected Publications


Factors Associated with COVID-19 Vaccination Promptness after Eligibility in a North Carolina Longitudinal Cohort Study.

Journal Article Vaccines (Basel) · October 26, 2023 Many studies identified factors associated with vaccination intention and hesitancy, but factors associated with vaccination promptness and the effect of vaccination intention on vaccination promptness are unknown. This study identified factors associated ... Full text Open Access Link to item Cite

Metabolic factors associated with incident fracture among older adults with type 2 diabetes mellitus: a nested case-control study.

Journal Article Osteoporos Int · July 2023 UNLABELLED: Older adults with type 2 diabetes mellitus have an increased risk of fracture despite a paradoxically higher average bone mineral density. This study identified additional markers of fracture risk in this at-risk population. Non-esterified fatt ... Full text Open Access Link to item Cite

Mitigation behavior prior to COVID-19 vaccination availability is associated with COVID-19 infection and time to vaccination.

Journal Article PLoS One · 2023 BACKGROUND: Mitigation behaviors reduce the incidence of COVID-19 infection. Determining characteristics of groups defined by mitigation behaviors compliance may be useful to inform targeted public health policies and interventions. This study aimed to ide ... Full text Open Access Link to item Cite

COVID-19 Infection Risk Among Previously Uninfected Adults: Development of a Prognostic Model.

Journal Article Health Serv Res Manag Epidemiol · 2023 BACKGROUND: Few models exist that incorporate measures from an array of individual characteristics to predict the risk of COVID-19 infection in the general population. The aim was to develop a prognostic model for COVID-19 using readily obtainable clinical ... Full text Open Access Link to item Cite

Comparison of a Blood Self-Collection System with Routine Phlebotomy for SARS-CoV-2 Antibody Testing.

Journal Article Diagnostics (Basel) · July 31, 2022 The Coronavirus Disease 2019 (COVID-19) pandemic forced researchers to reconsider in-person assessments due to transmission risk. We conducted a pilot study to evaluate the feasibility of using the Tasso-SST (Tasso, Inc, Seattle, Washington) device for blo ... Full text Open Access Link to item Cite

Lipid changes in the metabolome of a single case study with maple syrup urine disease (MSUD) after five days of improved diet adherence of controlled branched-chain amino acids (BCAA).

Journal Article Mol Genet Metab Rep · December 2020 BACKGROUND: Distinguishing systemic metabolic disruptions in maple syrup urine disease (MSUD) beyond amino acid pathways is under-investigated, yet important to understanding disease pathology and treatment options. METHODS: An adolescent female (15 years) ... Full text Open Access Link to item Cite

Electronic health records based phenotyping in next-generation clinical trials: a perspective from the NIH Health Care Systems Collaboratory.

Journal Article J Am Med Inform Assoc · December 2013 Widespread sharing of data from electronic health records and patient-reported outcomes can strengthen the national capacity for conducting cost-effective clinical trials and allow research to be embedded within routine care delivery. While pragmatic clini ... Full text Link to item Cite

A comparison of phenotype definitions for diabetes mellitus.

Journal Article J Am Med Inform Assoc · December 2013 OBJECTIVE: This study compares the yield and characteristics of diabetes cohorts identified using heterogeneous phenotype definitions. MATERIALS AND METHODS: Inclusion criteria from seven diabetes phenotype definitions were translated into query algorithms ... Full text Link to item Cite