Edward Daniel Levin
Professor in Psychiatry and Behavioral Sciences
Dr. Levin is Chief of the Neurobehavioral Research Lab in the Psychiatry Department of Duke University Medical Center. His primary academic appointment is as Professor in the Department of Psychiatry and Behavioral Sciences. He also has secondary appointments in the Department Pharmacology and Cancer Biology, the Department of Psychological and Brain Sciences and the Nicholas School of the Environment at Duke. His primary research effort is to understand basic neural interactions underlying cognitive function and addiction and to apply this knowledge to better understand cognitive dysfunction and addiction disorders and to develop novel therapeutic treatments.
The three main research components of his laboratory are focused on the themes of the basic neurobiology of cognition and addiction, neurobehavioral toxicology and the development of novel therapeutic treatments for cognitive dysfunction and substance abuse. Currently, our principal research focus concerns nicotine. We have documented the basic effects of nicotine on learningm memory and attention as well as nicotine self-administration. We are continuing with more mechanistic studies in rat models using selective lesions, local infusions and neurotransmitter interaction studies. We have found that nicotine improves memory performance not only in normal rats, but also in rats with lesions of hippocampal and basal forebrain connections. We are concentrating on alpha7 and alpha4beta2 nicotinic receptor subtypes in the hippocampus, amygdala , thalamus and frontal cortex and how they interact with dopamine D1 and D2 and glutamate NMDA systems with regard to memory and addiction. I am also conducting studies on human cognitive behavior. We have current studies to assess nicotine effects on attention, memory and mental processing speed in schizophrenics, Alzheimer's Disease patients and people with Attention Deficit Hyperactivity Disorder. In the area of neurobehavioral toxicology, I have continuing projects to characterize the adverse effects of prenatal and adolescent nicotine exposure. Our primary project in neurobehavioral toxicology focuses on the cognitive deficits caused by the marine toxins including domoic acid, ciguatera toxin and pfiesteria. We have documented a persistent neurobehavioral effects caused by Pfiesteria and domoic acid exposure. We are determining the neurobehavioral nature and mechanisms of this deficit. The basic and applied aims of our research complement each other nicely. The findings concerning neural mechanisms underlying cognitive function help direct the behavioral toxicology and therapeutic development studies, while the applied studies provide important functional information concerning the importance of the basic mechanisms under investigation.
The three main research components of his laboratory are focused on the themes of the basic neurobiology of cognition and addiction, neurobehavioral toxicology and the development of novel therapeutic treatments for cognitive dysfunction and substance abuse. Currently, our principal research focus concerns nicotine. We have documented the basic effects of nicotine on learningm memory and attention as well as nicotine self-administration. We are continuing with more mechanistic studies in rat models using selective lesions, local infusions and neurotransmitter interaction studies. We have found that nicotine improves memory performance not only in normal rats, but also in rats with lesions of hippocampal and basal forebrain connections. We are concentrating on alpha7 and alpha4beta2 nicotinic receptor subtypes in the hippocampus, amygdala , thalamus and frontal cortex and how they interact with dopamine D1 and D2 and glutamate NMDA systems with regard to memory and addiction. I am also conducting studies on human cognitive behavior. We have current studies to assess nicotine effects on attention, memory and mental processing speed in schizophrenics, Alzheimer's Disease patients and people with Attention Deficit Hyperactivity Disorder. In the area of neurobehavioral toxicology, I have continuing projects to characterize the adverse effects of prenatal and adolescent nicotine exposure. Our primary project in neurobehavioral toxicology focuses on the cognitive deficits caused by the marine toxins including domoic acid, ciguatera toxin and pfiesteria. We have documented a persistent neurobehavioral effects caused by Pfiesteria and domoic acid exposure. We are determining the neurobehavioral nature and mechanisms of this deficit. The basic and applied aims of our research complement each other nicely. The findings concerning neural mechanisms underlying cognitive function help direct the behavioral toxicology and therapeutic development studies, while the applied studies provide important functional information concerning the importance of the basic mechanisms under investigation.
Current Appointments & Affiliations
- Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences 2021
- Director, Integrated Toxicology Program, School of Medicine, Duke University 1995
- Associate Professor of Pharmacology & Cancer Biology, Pharmacology & Cancer Biology, Basic Science Departments 1998
- Professor in the Environmental Sciences and Policy Division, Environmental Sciences and Policy, Nicholas School of the Environment 2015
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1989
- Faculty Network Member of the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2008
- Affiliate of the Duke Initiative for Science & Society, Duke Science & Society, Initiatives 2014
Contact Information
- 323 Foster St, Durham, NC 27701
- Box 104790, Durham, NC 27710
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edlevin@duke.edu
(919) 681-6273
- Background
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Education, Training, & Certifications
- Ph.D., University of Wisconsin - Madison 1984
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Previous Appointments & Affiliations
- Professor of Psychology and Neuroscience, Psychology & Neuroscience, Trinity College of Arts & Sciences 2013 - 2022
- Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2003 - 2020
- Co-Director Center on Addiction and Behavior Change, Duke Institute for Brain Sciences, University Institutes and Centers 2013 - 2016
- Associate Professor of Nicholas School of the Environment, Nicholas School of the Environment, Duke University 1998 - 2007
- Associate Professor of Psychological and Brain Sciences, Psychology & Neuroscience, Trinity College of Arts & Sciences 2001 - 2006
- Associate Professor in Psychiatry and Behavioral Sciences with Tenure, Psychiatry & Behavioral Sciences, Clinical Science Departments 2000 - 2003
- Associate Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 1995 - 2000
- Assistant Professor of Pharmacology & Cancer Biology, Pharmacology & Cancer Biology, Basic Science Departments 1994 - 1998
- Assistant Professor in Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 1992 - 1995
- Assistant Research Professor in Psychiatry, Psychiatry & Behavioral Sciences, Clinical Science Departments 1992
- Recognition
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In the News
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AUG 15, 2014 Duke Research Blog -
DEC 6, 2013
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- Research
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Selected Grants
- Microglial sculpting of dopamine receptors in adolescence: implications for opioid use disorders awarded by National Institutes of Health 2022 - 2027
- Pharmacological Sciences Training Grant awarded by National Institutes of Health 2020 - 2025
- Duke University Program in Environmental Health awarded by National Institutes of Health 2013 - 2024
- Receptor-type protein in tyrosine phosphatase D (PTPRD) treatment with 7-BIA to reduce nicotine self-adminstration awarded by Biomedical Research Institute of New Mexico 2019 - 2022
- HAB toxin exposure and Alzheimer's disease susceptibility awarded by Woods Hole Oceanographic Institution 2019 - 2022
- Using Zebrafish to Help Identify Which Environmental Toxicants Could Increase Autism Risk awarded by Autism Research Institute 2019 - 2021
- Paternal Transgenerational Epigenetic Legacy from Use of Cannabis awarded by John Templeton Foundation 2017 - 2021
- Alzheimer's Disease, Genes, and Pesticide Use in the Agricultural Health Study awarded by National Institutes of Health 2014 - 2021
- Reinforcing effect of nicotine alone vs. nicotine plus other chemicals in tobacco awarded by Rose Research Center, LLC 2019 - 2020
- Pharmacological Sciences Training Program awarded by National Institutes of Health 1975 - 2020
- Study of Novel Treatment to Prevent Acquisition of Opiate Self-Administration in Rats awarded by Amygdala Neurosciences Inc. 2017 - 2019
- Duke University Program in Environmental Health awarded by National Institute of Environmental Health Sciences 2013 - 2019
- Advancing Mechanistic Understanding of Neurotoxic Contributors to Autism awarded by National Institutes of Health 2017 - 2018
- Establishing an AOP for the Role of the Vitamin D Receptor in Developmental Neurotoxicity awarded by North Carolina State University 2013 - 2018
- Acute and chronic nicotine modulation of reinforcement learning awarded by National Institutes of Health 2013 - 2017
- Pilot Project: Effects of Cannabis on the Epigenome of Humans and Rats awarded by John Templeton Foundation 2016 - 2017
- Screening for Potential Persisting Neurobehavioral Effects in Zebrafish following Developmental Exposure to Classes of Compounds: Flame Retardants, A Case Example awarded by National Institute of Environmental Health Sciences 2015 - 2017
- Complementary Neurotoxicological Insights from Fish, Flies, Bees and Worms Symposium awarded by National Institutes of Health 2015 - 2016
- Nicotinic Receptor Desensitization to Reduce Drug Self-Administration: Project 2 awarded by Georgetown University 2010 - 2015
- Atrazine Effects in the Brain: Pilot Study awarded by Environmental Protection Agency 2011 - 2012
- Role of HPA Axis in Adolescent Vulnerability to Drug Addiction awarded by National Institutes of Health 2006 - 2011
- Neurobehavioral Teratology Society: Zebrafish Symposium awarded by National Institutes of Health 2010 - 2011
- Adolescence: A Sensitive Period for Nicotine Addiction awarded by National Institutes of Health 2004 - 2010
- MARCKS Peptides and Memory awarded by National Institutes of Health 2009 - 2010
- Neuroimaging Attentional Impairment During Abstinence awarded by National Institutes of Health 2004 - 2009
- Nicotinic-Antipsychotic Drug Interactions and Cognition awarded by National Institutes of Health 2001 - 2006
- Marine Toxin Impacts on Neurobehavioral Function awarded by National Institutes of Health 2003 - 2004
- Non-Monotonic Dose-Toxicity Functions, Multiple Mechanisms of Effect: Impacts on Health & Public Policy awarded by Environmental Protection Agency 2002 - 2004
- Collaberative Research Training In Enviromental Toxicology awarded by Environmental Protection Agency 1998 - 2003
- Behavioral Genetics and Toxic Response awarded by National Institutes of Health 2002 - 2003
- Chronic Nicotine-Infusion Induced Memory Improvement awarded by National Institutes of Health 1998 - 2002
- Same awarded by National Institutes of Health 1997 - 1999
- Same awarded by Environmental Protection Agency 1998 - 1999
- Same awarded by National Institutes of Health 1999
- Integrated Toxicology awarded by National Institutes of Health 1995 - 1999
- Drive To Smoke And Dopamine Blockade awarded by National Institutes of Health 1994 - 1997
- The Effect Of Pfiesteriaon Learning And Memory In Rats awarded by Environmental Protection Agency 1997
- Neurobehavioral Effects Of Dinoflagellate Toxins In Rat awarded by NC Sea Grant 1996 - 1997
- Cholinergic-Dopaminergic Interactions And The Foundations awarded by National Science Foundation 1992 - 1997
- Scaling The Reinforcing Value Of Cigarette Smoke awarded by National Institutes of Health 1993 - 1994
- Cholinergic-Dopaminergic Interactions & The Foundations Of awarded by National Science Foundation 1993 - 1994
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External Relationships
- Philip Morris International
- Procter & Gamble Company
- Uppsala University
- Publications & Artistic Works
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Selected Publications
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Books
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Levin, E. D., and J. J. Buccafusco. Animal models of cognitive impairment, 2006.
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Levin, E. D. Nicotinic receptors in the nervous system, 2001.
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Academic Articles
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Levin, Edward D., Sharon Bushnell, M Christopher Newland, Jerrold Meyer, and William Boyes. “Introduction: The continuing importance of behavioral toxicology: In memory of Philip J. Bushnell, Ph.D.” Neurotoxicol Teratol 92 (June 2, 2022): 107107. https://doi.org/10.1016/j.ntt.2022.107107.Full Text Link to Item
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Hawkey, Andrew B., Erica Pippen, Bruny Kenou, Zade Holloway, Theodore A. Slotkin, Frederic J. Seidler, and Edward D. Levin. “Persistent neurobehavioral and neurochemical anomalies in middle-aged rats after maternal diazinon exposure.” Toxicology 472 (April 30, 2022): 153189. https://doi.org/10.1016/j.tox.2022.153189.Full Text Link to Item
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Rezvani, Amir H., Marty Cauley, and Edward D. Levin. “Time-dependent effects of nicotine on reversal of dizocilpine-induced attentional impairment in female rats.” Pharmacol Biochem Behav 215 (April 2022): 173359. https://doi.org/10.1016/j.pbb.2022.173359.Full Text Link to Item
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Joglekar, Rashmi, Marty Cauley, Taylor Lipsich, David L. Corcoran, Heather B. Patisaul, Edward D. Levin, Joel N. Meyer, Margaret M. McCarthy, and Susan K. Murphy. “Developmental nicotine exposure and masculinization of the rat preoptic area.” Neurotoxicology 89 (March 2022): 41–54. https://doi.org/10.1016/j.neuro.2022.01.005.Full Text Link to Item
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Levin, Edward D., Corinne Wells, Susan Slade, Joshua Johnson, Ann Petro, Amir H. Rezvani, and Jed E. Rose. “Chronic infusions of mecamylamine into the medial habenula: Effects on nicotine self-administration in rats.” Behav Brain Res 416 (January 7, 2022): 113574. https://doi.org/10.1016/j.bbr.2021.113574.Full Text Link to Item
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Holloway, Z., A. B. Hawkey, E. Pippen, H. White, V. Katragadda, B. Kenou, C. Wells, S. K. Murphy, A. H. Rezvani, and E. D. Levin. “Corrigendum to "Paternal cannabis extract exposure in rats: Preconception timing effects on neurobehavioral effects in offspring" [Neurotoxicology 81 (2020) 180-188].” Neurotoxicology 87 (December 2021): 258. https://doi.org/10.1016/j.neuro.2021.08.009.Full Text Link to Item
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Slotkin, Theodore A., Edward D. Levin, and Frederic J. Seidler. “Paternal Cannabis Exposure Prior to Mating, but Not Δ9-Tetrahydrocannabinol, Elicits Deficits in Dopaminergic Synaptic Activity in the Offspring.” Toxicol Sci 184, no. 2 (November 24, 2021): 252–64. https://doi.org/10.1093/toxsci/kfab117.Full Text Open Access Copy Link to Item
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Levin, Edward D., Corinne Wells, Caroline Pace, Grant Abass, Andrew Hawkey, Zade Holloway, Amir H. Rezvani, and Jed E. Rose. “Self-administration by female rats of low doses of nicotine alone vs. nicotine in tobacco smoke extract.” Drug Alcohol Depend 228 (November 1, 2021): 109073. https://doi.org/10.1016/j.drugalcdep.2021.109073.Full Text Link to Item
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Rezvani, Amir H., Corinne Wells, Andrew Hawkey, Graham Blair, Reese Koburov, Ashley Ko, Andrea Schwartz, Veronica J. Kim, and Edward D. Levin. “Differential behavioral functioning in the offspring of rats with high vs. low self-administration of the opioid agonist remifentanil.” Eur J Pharmacol 909 (October 15, 2021): 174407. https://doi.org/10.1016/j.ejphar.2021.174407.Full Text Link to Item
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Jao, Nancy C., Edward D. Levin, Melissa A. Simon, and Brian Hitsman. “Differences in Cognitive Task Performance, Reinforcement Enhancement, and Nicotine Dependence Between Menthol and Nonmenthol Cigarette Smokers.” Nicotine Tob Res 23, no. 11 (October 7, 2021): 1902–10. https://doi.org/10.1093/ntr/ntab120.Full Text Link to Item
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Boyda, Jonna, Andrew B. Hawkey, Zade R. Holloway, Rafael Trevisan, Richard T. Di Giulio, and Edward D. Levin. “The organophosphate insecticide diazinon and aging: Neurobehavioral and mitochondrial effects in zebrafish exposed as embryos or during aging.” Neurotoxicol Teratol 87 (September 2021): 107011. https://doi.org/10.1016/j.ntt.2021.107011.Full Text Link to Item
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Hawkey, Andrew B., Zade Holloway, Cassandra Dean, Reese Koburov, Theodore A. Slotkin, Frederic J. Seidler, and Edward D. Levin. “Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact?” Neurotoxicol Teratol 87 (September 2021): 106985. https://doi.org/10.1016/j.ntt.2021.106985.Full Text Link to Item
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Holloway, Zade, Andrew Hawkey, Helina Asrat, Nidhi Boinapally, and Edward D. Levin. “The use of tocofersolan as a rescue agent in larval zebrafish exposed to benzo[a]pyrene in early development.” Neurotoxicology 86 (September 2021): 78–84. https://doi.org/10.1016/j.neuro.2021.07.003.Full Text Link to Item
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Hawkey, Andrew B., Julia Hoeng, Manuel C. Peitsch, Edward D. Levin, and Kyoko Koshibu. “Subchronic effects of plant alkaloids on anxiety-like behavior in zebrafish.” Pharmacol Biochem Behav 207 (August 2021): 173223. https://doi.org/10.1016/j.pbb.2021.173223.Full Text Link to Item
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Levin, Edward D. “Invited Perspective: Does Developmental Adaptation Pose Risks with Changing Toxicant Exposures?” Environ Health Perspect 129, no. 8 (August 2021): 81302. https://doi.org/10.1289/EHP9560.Full Text Open Access Copy Link to Item
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Levin, Edward D., Corinne Wells, Andrew Hawkey, Zade Holloway, Graham Blair, Alexander Vierling, Ashley Ko, et al. “Correction to: Amitifadine, a triple reuptake inhibitor, reduces self-administration of the opiate remifentanil in rats.” Psychopharmacology (Berl) 238, no. 4 (April 2021): 1227. https://doi.org/10.1007/s00213-021-05794-y.Full Text Link to Item
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Levin, Edward D., Diana Dow-Edwards, and Heather Patisaul. “Introduction to sex differences in neurotoxic effects.” Neurotoxicol Teratol 83 (January 2021): 106931. https://doi.org/10.1016/j.ntt.2020.106931.Full Text Link to Item
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Schrott, Rose, Susan K. Murphy, Jennifer L. Modliszewski, Dillon E. King, Bendu Hill, Nilda Itchon-Ramos, Douglas Raburn, et al. “Refraining from use diminishes cannabis-associated epigenetic changes in human sperm.” Environ Epigenet 7, no. 1 (2021): dvab009. https://doi.org/10.1093/eep/dvab009.Full Text Link to Item
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Vorhees, Charles V., Michael T. Williams, Andrew B. Hawkey, and Edward D. Levin. “Translating Neurobehavioral Toxicity Across Species From Zebrafish to Rats to Humans: Implications for Risk Assessment.” Front Toxicol 3 (2021): 629229. https://doi.org/10.3389/ftox.2021.629229.Full Text Link to Item
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Holloway, Zade, Reese Koburov, Andrew Hawkey, and Edward D. Levin. “Measuring attention in rats with a visual signal detection task: Signal intensity vs. signal duration.” Pharmacol Biochem Behav 199 (December 2020): 173069. https://doi.org/10.1016/j.pbb.2020.173069.Full Text Link to Item
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Acharya, K. S., R. Schrott, C. Grenier, Z. Huang, Z. Holloway, A. Hawkey, E. D. Levin, and S. K. Murphy. “Epigenetic alterations in cytochrome P450 oxidoreductase (Por) in sperm of rats exposed to tetrahydrocannabinol (THC).” Scientific Reports 10, no. 1 (December 1, 2020). https://doi.org/10.1038/s41598-020-69204-7.Full Text
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Holloway, Zade R., Andrew B. Hawkey, Alexandra K. Torres, Janequia Evans, Erica Pippen, Hannah White, Vaishnavi Katragadda, et al. “Paternal cannabis extract exposure in rats: Preconception timing effects on neurodevelopmental behavior in offspring.” Neurotoxicology 81 (December 2020): 180–88. https://doi.org/10.1016/j.neuro.2020.10.007.Full Text Link to Item
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Oliveri, Anthony N., Megan Knuth, Lilah Glazer, Jordan Bailey, Seth W. Kullman, and Edward D. Levin. “Zebrafish show long-term behavioral impairments resulting from developmental vitamin D deficiency.” Physiol Behav 224 (October 1, 2020): 113016. https://doi.org/10.1016/j.physbeh.2020.113016.Full Text Link to Item
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Schrott, Rose, Maya Rajavel, Kelly Acharya, Zhiqing Huang, Chaitanya Acharya, Andrew Hawkey, Erica Pippen, H Kim Lyerly, Edward D. Levin, and Susan K. Murphy. “Sperm DNA methylation altered by THC and nicotine: Vulnerability of neurodevelopmental genes with bivalent chromatin.” Sci Rep 10, no. 1 (September 29, 2020): 16022. https://doi.org/10.1038/s41598-020-72783-0.Full Text Link to Item
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Kwan, Leslie Y., David L. Eaton, Susan L. Andersen, Diana Dow-Edwards, Edward D. Levin, John Talpos, Charles V. Vorhees, and Abby A. Li. “This is your teen brain on drugs: In search of biological factors unique to dependence toxicity in adolescence.” Neurotoxicol Teratol 81 (September 2020): 106916. https://doi.org/10.1016/j.ntt.2020.106916.Full Text Link to Item
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Oliveri, Anthony N., Lilah Glazer, Debabrata Mahapatra, Seth W. Kullman, and Edward D. Levin. “Developmental exposure of zebrafish to vitamin D receptor acting drugs and environmental toxicants disrupts behavioral function.” Neurotoxicol Teratol 81 (September 2020): 106902. https://doi.org/10.1016/j.ntt.2020.106902.Full Text Link to Item
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Acharya, Kelly S., Rose Schrott, Carole Grenier, Zhiqing Huang, Zade Holloway, Andrew Hawkey, Edward D. Levin, and Susan K. Murphy. “Epigenetic alterations in cytochrome P450 oxidoreductase (Por) in sperm of rats exposed to tetrahydrocannabinol (THC).” Sci Rep 10, no. 1 (July 23, 2020): 12251. https://doi.org/10.1038/s41598-020-69204-7.Full Text Open Access Copy Link to Item
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Levin, Edward D., Corinne Wells, Andrew Hawkey, Zade Holloway, Graham Blair, Alexander Vierling, Ashley Ko, et al. “Amitifadine, a triple reuptake inhibitor, reduces self-administration of the opiate remifentanil in rats.” Psychopharmacology (Berl) 237, no. 6 (June 2020): 1681–89. https://doi.org/10.1007/s00213-020-05489-w.Full Text Link to Item
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Blair, Graham, Corinne Wells, Ashley Ko, John Modarres, Caroline Pace, James M. Davis, Amir H. Rezvani, Jed E. Rose, and Edward D. Levin. “Dextromethorphan and bupropion reduces high level remifentanil self-administration in rats.” Pharmacol Biochem Behav 193 (June 2020): 172919. https://doi.org/10.1016/j.pbb.2020.172919.Full Text Open Access Copy Link to Item
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Hollander, Jonathan A., Deborah A. Cory-Slechta, Felice N. Jacka, Steven T. Szabo, Tomás R. Guilarte, Staci D. Bilbo, Carolyn J. Mattingly, et al. “Beyond the looking glass: recent advances in understanding the impact of environmental exposures on neuropsychiatric disease.” Neuropsychopharmacology 45, no. 7 (June 2020): 1086–96. https://doi.org/10.1038/s41386-020-0648-5.Full Text Link to Item
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Slotkin, Theodore A., Samantha Skavicus, Edward D. Levin, and Frederic J. Seidler. “Paternal Δ9-Tetrahydrocannabinol Exposure Prior to Mating Elicits Deficits in Cholinergic Synaptic Function in the Offspring.” Toxicol Sci 174, no. 2 (April 1, 2020): 210–17. https://doi.org/10.1093/toxsci/kfaa004.Full Text Link to Item
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Hawkey, Andrew B., Lilah Glazer, Cassandra Dean, Corinne N. Wells, Kathryn-Ann Odamah, Theodore A. Slotkin, Frederic J. Seidler, and Edward D. Levin. “Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish.” Neurotoxicol Teratol 78 (March 2020): 106853. https://doi.org/10.1016/j.ntt.2019.106853.Full Text Link to Item
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Levin, Edward D., Corinne Wells, Susan Slade, Michelle Lee, Anthony A. McKinney, Jed E. Rose, and Amir H. Rezvani. “Prolonging the Reduction of Nicotine Self-Administration in Rats by Coadministering Chronic Nicotine With Amitifadine, a Triple Monoamine Reuptake Inhibitor With CYP2B6 Inhibitory Actions.” Nicotine Tob Res 22, no. 2 (February 6, 2020): 232–37. https://doi.org/10.1093/ntr/ntz054.Full Text Open Access Copy Link to Item
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Hawkey, Andrew, Erica Pippen, Hannah White, Joseph Kim, Eva Greengrove, Bruny Kenou, Zade Holloway, and Edward D. Levin. “Gestational and perinatal exposure to diazinon causes long-lasting neurobehavioral consequences in the rat.” Toxicology 429 (January 15, 2020): 152327. https://doi.org/10.1016/j.tox.2019.152327.Full Text Link to Item
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Schrott, Rose, Kelly Acharya, Nilda Itchon-Ramos, Andrew B. Hawkey, Erica Pippen, John T. Mitchell, Scott H. Kollins, Edward D. Levin, and Susan K. Murphy. “Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm.” Epigenetics 15, no. 1–2 (January 2020): 161–73. https://doi.org/10.1080/15592294.2019.1656158.Full Text Link to Item
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Willette, Blair K. A., Anica Nangia, Sarah Howard, Devon DiPalma, Collin McMillan, Sonum Tharwani, Janequia Evans, et al. “Acute and chronic interactive treatments of serotonin 5HT2C and dopamine D1 receptor systems for decreasing nicotine self-administration in female rats.” Pharmacol Biochem Behav 186 (November 2019): 172766. https://doi.org/10.1016/j.pbb.2019.172766.Full Text Link to Item
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Levin, Edward D., Corinne Wells, Leah Yao, Wendi Guo, Anica Nangia, Sarah Howard, Erica Pippen, Andrew B. Hawkey, Jed E. Rose, and Amir H. Rezvani. “Chronic memantine decreases nicotine self-administration in rats.” Eur J Pharmacol 861 (October 15, 2019): 172592. https://doi.org/10.1016/j.ejphar.2019.172592.Full Text Link to Item
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Hawkey, Andrew, Shaqif Junaid, Leah Yao, Zachary Spiera, Hannah White, Marty Cauley, and Edward D. Levin. “Gestational exposure to nicotine and/or benzo[a]pyrene causes long-lasting neurobehavioral consequences.” Birth Defects Res 111, no. 17 (October 15, 2019): 1248–58. https://doi.org/10.1002/bdr2.1568.Full Text Link to Item
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Slotkin, Theodore A., Samantha Skavicus, Ashley Ko, Edward D. Levin, and Frederic J. Seidler. “Perinatal diazinon exposure compromises the development of acetylcholine and serotonin systems.” Toxicology 424 (August 1, 2019): 152240. https://doi.org/10.1016/j.tox.2019.152240.Full Text Link to Item
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Hawkey, Andrew B., Hannah White, Erica Pippen, Eva Greengrove, Amir H. Rezvani, Susan K. Murphy, and Edward D. Levin. “Paternal nicotine exposure in rats produces long-lasting neurobehavioral effects in the offspring.” Neurotoxicol Teratol 74 (July 2019): 106808. https://doi.org/10.1016/j.ntt.2019.05.001.Full Text Open Access Copy Link to Item
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Levin, Edward D., Andrew B. Hawkey, Brandon J. Hall, Marty Cauley, Susan Slade, Elisa Yazdani, Bruny Kenou, et al. “Paternal THC exposure in rats causes long-lasting neurobehavioral effects in the offspring.” Neurotoxicol Teratol 74 (July 2019): 106806. https://doi.org/10.1016/j.ntt.2019.04.003.Full Text Link to Item
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Westerink, Remco H. S., Christoph van Thriel, Edward D. Levin, and Timothy J. Shafer. “From molecular mechanisms to functional impact: Developing integrated analyses in neurotoxicology - The 16th biennial meeting International Neurotoxicology Association and 8th meeting of the NeuroToxicity Society.” Neurotoxicology 72 (May 2019): 125–26. https://doi.org/10.1016/j.neuro.2018.11.002.Full Text Link to Item
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Rezvani, Amir H., Corinne Wells, Susan Slade, Yingxian Xiao, Kenneth J. Kellar, and Edward D. Levin. “Oral sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, reduces nicotine self-administration in rats.” Pharmacol Biochem Behav 179 (April 2019): 109–12. https://doi.org/10.1016/j.pbb.2019.02.007.Full Text Link to Item
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Slotkin, Theodore A., Samantha Skavicus, Ashley Ko, Edward D. Levin, and Frederic J. Seidler. “Corrigendum to "The Developmental Neurotoxicity of Tobacco Smoke Can Be Mimicked by a Combination of Nicotine and Benzo[a]pyrene: Effects on Cholinergic and Serotonergic Systems".” Toxicol Sci 168, no. 1 (March 1, 2019): 280. https://doi.org/10.1093/toxsci/kfy304.Full Text Link to Item
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Ideraabdullah, Folami Y., Anthony M. Belenchia, Cheryl Susan Rosenfeld, Seth W. Kullman, Megan Knuth, Debrata Mahapatra, Michael Bereman, Edward D. Levin, and Catherine Ann Peterson. “Maternal vitamin D deficiency and developmental origins of health and disease (DOHaD).” J Endocrinol, March 1, 2019. https://doi.org/10.1530/JOE-18-0541.Full Text Link to Item
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Levin, Edward D., Amir H. Rezvani, Corinne Wells, Susan Slade, Venkata M. Yenugonda, Yong Liu, Milton L. Brown, Yingxian Xiao, and Kenneth J. Kellar. “α4β2 Nicotinic receptor desensitizing compounds can decrease self-administration of cocaine and methamphetamine in rats.” Eur J Pharmacol 845 (February 15, 2019): 1–7. https://doi.org/10.1016/j.ejphar.2018.12.010.Full Text Link to Item
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Oliveri, Anthony N., and Edward D. Levin. “Dopamine D1 and D2 receptor antagonism during development alters later behavior in zebrafish.” Behav Brain Res 356 (January 1, 2019): 250–56. https://doi.org/10.1016/j.bbr.2018.08.028.Full Text Link to Item
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Slotkin, Theodore A., Samantha Skavicus, Ashley Ko, Edward D. Levin, and Frederic J. Seidler. “The Developmental Neurotoxicity of Tobacco Smoke Can Be Mimicked by a Combination of Nicotine and Benzo[a]Pyrene: Effects on Cholinergic and Serotonergic Systems.” Toxicol Sci 167, no. 1 (January 1, 2019): 293–304. https://doi.org/10.1093/toxsci/kfy241.Full Text Link to Item
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DiPalma, Devon, Amir H. Rezvani, Blair Willette, Corinne Wells, Susan Slade, Brandon J. Hall, and Edward D. Levin. “Persistent attenuation of nicotine self-administration in rats by co-administration of chronic nicotine infusion with the dopamine D1 receptor antagonist SCH-23390 or the serotonin 5-HT2C agonist lorcaserin.” Pharmacol Biochem Behav 176 (January 2019): 16–22. https://doi.org/10.1016/j.pbb.2018.11.002.Full Text Link to Item
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Rezvani, A. H., C. Wells, P. Strumph, I. Diamond, B. K. Blackburn, and E. D. Levin. “Risk for opioid abuse is diminished by inhibiting aldehyde dehydrogenase-2 (ALDH-2) in rats.” Journal of Drug and Alcohol Research 8 (January 1, 2019). https://doi.org/10.4303/jdar/236076.Full Text
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Pitt, Jordan A., Rafael Trevisan, Andrey Massarsky, Jordan S. Kozal, Edward D. Levin, and Richard T. Di Giulio. “Maternal transfer of nanoplastics to offspring in zebrafish (Danio rerio): A case study with nanopolystyrene.” Sci Total Environ 643 (December 1, 2018): 324–34. https://doi.org/10.1016/j.scitotenv.2018.06.186.Full Text Link to Item
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Glazer, Lilah, Andrew B. Hawkey, Corinne N. Wells, Meghan Drastal, Kathryn-Ann Odamah, Mamta Behl, and Edward D. Levin. “Developmental Exposure to Low Concentrations of Organophosphate Flame Retardants Causes Life-Long Behavioral Alterations in Zebrafish.” Toxicol Sci 165, no. 2 (October 1, 2018): 487–98. https://doi.org/10.1093/toxsci/kfy173.Full Text Link to Item
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Cauley, Marty, Brandon J. Hall, Yael Abreu-Villaça, Shaqif Junaid, Hannah White, Abtin Kiany, Theodore A. Slotkin, and Edward D. Levin. “Critical developmental periods for effects of low-level tobacco smoke exposure on behavioral performance.” Neurotoxicology 68 (September 2018): 81–87. https://doi.org/10.1016/j.neuro.2018.07.012.Full Text Link to Item
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Massarsky, Andrey, Nishad Jayasundara, Lilah Glazer, Edward D. Levin, G. L. Prasad, and Richard T. Di Giulio. “Outcomes of developmental exposure to total particulate matter from cigarette smoke in zebrafish (Danio rerio).” Neurotoxicology 68 (September 2018): 101–14. https://doi.org/10.1016/j.neuro.2018.07.003.Full Text Link to Item
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“Obituary—Philip J. Bushnell, Ph.D. (1947–2018).” Neurotoxicology and Teratology 69 (September 2018): 73–74. https://doi.org/10.1016/j.ntt.2018.08.002.Full Text
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Oliveri, Anthony N., Erica Ortiz, and Edward D. Levin. “Developmental exposure to an organophosphate flame retardant alters later behavioral responses to dopamine antagonism in zebrafish larvae.” Neurotoxicol Teratol 67 (May 2018): 25–30. https://doi.org/10.1016/j.ntt.2018.03.002.Full Text Link to Item
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Glazer, Lilah, Corinne N. Wells, Meghan Drastal, Kathryn-Ann Odamah, Richard E. Galat, Mamta Behl, and Edward D. Levin. “Developmental exposure to low concentrations of two brominated flame retardants, BDE-47 and BDE-99, causes life-long behavioral alterations in zebrafish.” Neurotoxicology 66 (May 2018): 221–32. https://doi.org/10.1016/j.neuro.2017.09.007.Full Text Link to Item
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Rezvani, Amir H., Yousef Tizabi, Susan Slade, Bruk Getachew, and Edward D. Levin. “Sub-anesthetic doses of ketamine attenuate nicotine self-administration in rats.” Neurosci Lett 668 (March 6, 2018): 98–102. https://doi.org/10.1016/j.neulet.2018.01.022.Full Text Link to Item
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Levin, Edward D., Corrine Wells, Susan Slade, and Amir H. Rezvani. “Mutually augmenting interactions of dextromethorphan and sazetidine-A for reducing nicotine self-administration in rats.” Pharmacol Biochem Behav 166 (March 2018): 42–47. https://doi.org/10.1016/j.pbb.2018.01.005.Full Text Link to Item
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Massarsky, Andrey, Ayham Abdel, Lilah Glazer, Edward D. Levin, and Richard T. Di Giulio. “Neurobehavioral effects of 1,2-propanediol in zebrafish (Danio rerio).” Neurotoxicology 65 (March 2018): 111–24. https://doi.org/10.1016/j.neuro.2018.02.007.Full Text Link to Item
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Murphy, Susan K., Nilda Itchon-Ramos, Zachary Visco, Zhiqing Huang, Carole Grenier, Rose Schrott, Kelly Acharya, et al. “Cannabinoid exposure and altered DNA methylation in rat and human sperm.” Epigenetics 13, no. 12 (2018): 1208–21. https://doi.org/10.1080/15592294.2018.1554521.Full Text Open Access Copy Link to Item
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Pitt, Jordan A., Jordan S. Kozal, Nishad Jayasundara, Andrey Massarsky, Rafael Trevisan, Nick Geitner, Mark Wiesner, Edward D. Levin, and Richard T. Di Giulio. “Uptake, tissue distribution, and toxicity of polystyrene nanoparticles in developing zebrafish (Danio rerio).” Aquat Toxicol 194 (January 2018): 185–94. https://doi.org/10.1016/j.aquatox.2017.11.017.Full Text Link to Item
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Lacagnina, Michael J., Ashley M. Kopec, Stewart S. Cox, Richa Hanamsagar, Corinne Wells, Susan Slade, Peter M. Grace, Linda R. Watkins, Edward D. Levin, and Staci D. Bilbo. “Opioid Self-Administration is Attenuated by Early-Life Experience and Gene Therapy for Anti-Inflammatory IL-10 in the Nucleus Accumbens of Male Rats.” Neuropsychopharmacology 42, no. 11 (October 2017): 2128–40. https://doi.org/10.1038/npp.2017.82.Full Text Link to Item
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Rezvani, Amir H., Susan Slade, Corinne Wells, Venkata M. Yenugonda, Yong Liu, Milton L. Brown, Yingxian Xiao, Kenneth J. Kellar, and Edward D. Levin. “Differential efficacies of the nicotinic α4β2 desensitizing agents in reducing nicotine self-administration in female rats.” Psychopharmacology (Berl) 234, no. 17 (September 2017): 2517–23. https://doi.org/10.1007/s00213-017-4641-6.Full Text Link to Item
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Massarsky, Andrey, Ayham Abdel, Lilah Glazer, Edward D. Levin, and Richard T. Di Giulio. “Exposure to 1,2-Propanediol Impacts Early Development of Zebrafish (Danio rerio) and Induces Hyperactivity.” Zebrafish 14, no. 3 (June 2017): 216–22. https://doi.org/10.1089/zeb.2016.1400.Full Text Link to Item
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Hall, Brandon J., Yael Abreu-Villaça, Marty Cauley, Shaqif Junaid, Hannah White, Abtin Kiany, and Edward D. Levin. “The ventral hippocampal muscarinic cholinergic system plays a key role in sexual dimorphisms of spatial working memory in rats.” Neuropharmacology 117 (May 1, 2017): 106–13. https://doi.org/10.1016/j.neuropharm.2017.01.019.Full Text Link to Item
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Thriel, Christoph van, Ed Levin, Pam Lein, Lucio G. Costa, and Remco H. S. Westerink. “Neural mechanisms of functional impairment across the lifespan: The 15th Biennial Meeting of the International Neurotoxicology Association and 39th Annual Meeting of the Neurobehavioral Teratology Society.” Neurotoxicology 59 (March 2017): 131–32. https://doi.org/10.1016/j.neuro.2017.03.003.Full Text Link to Item
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Abreu-Villaça, Yael, and Edward D. Levin. “Developmental neurotoxicity of succeeding generations of insecticides.” Environment International 99 (February 2017): 55–77. https://doi.org/10.1016/j.envint.2016.11.019.Full Text
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Macaulay, Laura J., Melissa Chernick, Albert Chen, David E. Hinton, Jordan M. Bailey, Seth W. Kullman, Edward D. Levin, and Heather M. Stapleton. “Exposure to a PBDE/OH-BDE mixture alters juvenile zebrafish (Danio rerio) development.” Environ Toxicol Chem 36, no. 1 (January 2017): 36–48. https://doi.org/10.1002/etc.3535.Full Text Link to Item
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Slotkin, Theodore A., Ashley Stadler, Samantha Skavicus, Jennifer Card, Jonathan Ruff, Edward D. Levin, and Frederic J. Seidler. “Is There a Critical Period for the Developmental Neurotoxicity of Low-Level Tobacco Smoke Exposure?” Toxicol Sci 155, no. 1 (January 2017): 75–84. https://doi.org/10.1093/toxsci/kfw180.Full Text Link to Item
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Rezvani, Amir H., Edward D. Levin, Marty Cauley, Bruk Getachew, and Yousef Tizabi. “Ketamine Differentially Attenuates Alcohol Intake in Male Versus Female Alcohol Preferring (P) Rats.” J Drug Alcohol Res 6 (2017). https://doi.org/10.4303/jdar/236030.Full Text Link to Item
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Slotkin, Theodore A., Samantha Skavicus, Jennifer Card, Edward D. Levin, and Frederic J. Seidler. “Diverse neurotoxicants target the differentiation of embryonic neural stem cells into neuronal and glial phenotypes.” Toxicology 372 (November 30, 2016): 42–51. https://doi.org/10.1016/j.tox.2016.10.015.Full Text Link to Item
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Petro, Ann, Hannah G. Sexton, Caroline Miranda, Anit Rastogi, Jonathan H. Freedman, and Edward D. Levin. “Persisting neurobehavioral effects of developmental copper exposure in wildtype and metallothionein 1 and 2 knockout mice.” Bmc Pharmacol Toxicol 17, no. 1 (November 2, 2016): 55. https://doi.org/10.1186/s40360-016-0096-3.Full Text Link to Item
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Rezvani, Amir H., Marty C. Cauley, Susan Slade, Corinne Wells, Stanley Glick, Jed E. Rose, and Edward D. Levin. “Acute oral 18-methoxycoronaridine (18-MC) decreases both alcohol intake and IV nicotine self-administration in rats.” Pharmacol Biochem Behav 150–151 (November 2016): 153–57. https://doi.org/10.1016/j.pbb.2016.10.010.Full Text Link to Item
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Levin, Edward D., Brandon J. Hall, Autri Chattopadhyay, Susan Slade, Corinne Wells, Amir H. Rezvani, and Jed E. Rose. “Reduction of nicotine self-administration by chronic nicotine infusion with H1 histamine blockade in female rats.” Psychopharmacology (Berl) 233, no. 15–16 (August 2016): 3009–15. https://doi.org/10.1007/s00213-016-4347-1.Full Text Link to Item
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Hall, Brandon J., Marty Cauley, Dennis A. Burke, Abtin Kiany, Theodore A. Slotkin, and Edward D. Levin. “Cognitive and Behavioral Impairments Evoked by Low-Level Exposure to Tobacco Smoke Components: Comparison with Nicotine Alone.” Toxicol Sci 151, no. 2 (June 2016): 236–44. https://doi.org/10.1093/toxsci/kfw042.Full Text Link to Item
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Levin, Edward D. “Crumbling Infrastructure and Learning Impairment: A Call for Responsibility.” Environ Health Perspect 124, no. 5 (May 1, 2016): A79. https://doi.org/10.1289/EHP69.Full Text Link to Item
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Bao, Xuhui, Vidyalakshmi Chandramohan, Randall P. Reynolds, John N. Norton, William C. Wetsel, Ramona M. Rodriguiz, Dipendra K. Aryal, et al. “Preclinical toxicity evaluation of a novel immunotoxin, D2C7-(scdsFv)-PE38KDEL, administered via intracerebral convection-enhanced delivery in rats.” Invest New Drugs 34, no. 2 (April 2016): 149–58. https://doi.org/10.1007/s10637-015-0318-3.Full Text Link to Item
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Briggs, Scott A., Brandon J. Hall, Corinne Wells, Susan Slade, Paul Jaskowski, Margaret Morrison, Amir H. Rezvani, Jed E. Rose, and Edward D. Levin. “Dextromethorphan interactions with histaminergic and serotonergic treatments to reduce nicotine self-administration in rats.” Pharmacol Biochem Behav 142 (March 2016): 1–7. https://doi.org/10.1016/j.pbb.2015.12.004.Full Text Link to Item
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Bailey, Jordan M., Anthony N. Oliveri, Nishika Karbhari, Roy A. J. Brooks, Amberlene J. De La Rocha, Sheila Janardhan, and Edward D. Levin. “Persistent behavioral effects following early life exposure to retinoic acid or valproic acid in zebrafish.” Neurotoxicology 52 (January 2016): 23–33. https://doi.org/10.1016/j.neuro.2015.10.001.Full Text Link to Item
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Brown, D. R., J. M. Bailey, A. N. Oliveri, E. D. Levin, and R. T. Di Giulio. “Developmental exposure to a complex PAH mixture causes persistent behavioral effects in naive Fundulus heteroclitus (killifish) but not in a population of PAH-adapted killifish.” Neurotoxicol Teratol 53 (January 2016): 55–63. https://doi.org/10.1016/j.ntt.2015.10.007.Full Text Open Access Copy Link to Item
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Rezvani, A. H., E. D. Levin, C. Wells, S. Slade, M. Morrison, L. Marshall, M. Morris, J. Confino, C. Allenby, and L. Lumeng. “Different lines of rats selectively-bred for high alcohol-drinking demonstrate disparate preferences for nicotine self-administration.” Journal of Drug and Alcohol Research 2016, no. 5 (January 1, 2016). https://doi.org/10.4303/jdar/235972.Full Text Open Access Copy
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Bailey, Jordan M., Anthony N. Oliveri, and Edward D. Levin. “Pharmacological analyses of learning and memory in zebrafish (Danio rerio).” Pharmacol Biochem Behav 139 Pt B (December 2015): 103–11. https://doi.org/10.1016/j.pbb.2015.03.006.Full Text Link to Item
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Levin, Edward D., Allan V. Kalueff, and Robert T. Gerlai. “Perspectives on zebrafish neurobehavioral pharmacology.” Pharmacol Biochem Behav 139 Pt B (December 2015): 93. https://doi.org/10.1016/j.pbb.2015.11.007.Full Text Link to Item
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Hall, Brandon J., Susan Slade, Cheyenne Allenby, Munir G. Kutlu, and Edward D. Levin. “Neuro-anatomic mapping of dopamine D1 receptor involvement in nicotine self-administration in rats.” Neuropharmacology 99 (December 2015): 689–95. https://doi.org/10.1016/j.neuropharm.2015.03.005.Full Text Link to Item
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Bailey, J. M., and E. D. Levin. “Neurotoxicity of FireMaster 550® in zebrafish (Danio rerio): Chronic developmental and acute adolescent exposures.” Neurotoxicol Teratol 52, no. Pt B (November 2015): 210–19. https://doi.org/10.1016/j.ntt.2015.07.001.Full Text Link to Item
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Levin, Edward D. “Learning about cognition risk with the radial-arm maze in the developmental neurotoxicology battery.” Neurotoxicol Teratol 52, no. Pt A (November 2015): 88–92. https://doi.org/10.1016/j.ntt.2015.05.007.Full Text Link to Item
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Macaulay, Laura J., Jordan M. Bailey, Edward D. Levin, and Heather M. Stapleton. “Persisting effects of a PBDE metabolite, 6-OH-BDE-47, on larval and juvenile zebrafish swimming behavior.” Neurotoxicol Teratol 52, no. Pt B (November 2015): 119–26. https://doi.org/10.1016/j.ntt.2015.05.002.Full Text Link to Item
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Oliveri, A. N., J. M. Bailey, and E. D. Levin. “Developmental exposure to organophosphate flame retardants causes behavioral effects in larval and adult zebrafish.” Neurotoxicol Teratol 52, no. Pt B (November 2015): 220–27. https://doi.org/10.1016/j.ntt.2015.08.008.Full Text Link to Item
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Levin, Edward D., Corinne Wells, Joshua E. Johnson, Amir H. Rezvani, Frank P. Bymaster, and Jed E. Rose. “Amitifadine, a triple monoamine re-uptake inhibitor, reduces nicotine self-administration in female rats.” Eur J Pharmacol 764 (October 5, 2015): 30–37. https://doi.org/10.1016/j.ejphar.2015.06.041.Full Text Link to Item
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Massarsky, Andrey, Nishad Jayasundara, Jordan M. Bailey, Anthony N. Oliveri, Edward D. Levin, G. L. Prasad, and Richard T. Di Giulio. “Teratogenic, bioenergetic, and behavioral effects of exposure to total particulate matter on early development of zebrafish (Danio rerio) are not mimicked by nicotine.” Neurotoxicol Teratol 51 (September 2015): 77–88. https://doi.org/10.1016/j.ntt.2015.09.006.Full Text Link to Item
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Slotkin, Theodore A., Samantha Skavicus, Jennifer Card, Ashley Stadler, Edward D. Levin, and Frederic J. Seidler. “Developmental Neurotoxicity of Tobacco Smoke Directed Toward Cholinergic and Serotonergic Systems: More Than Just Nicotine.” Toxicol Sci 147, no. 1 (September 2015): 178–89. https://doi.org/10.1093/toxsci/kfv123.Full Text Link to Item
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Larrauri, José A., Dennis A. Burke, Brandon J. Hall, and Edward D. Levin. “Role of nicotinic receptors in the lateral habenula in the attenuation of amphetamine-induced prepulse inhibition deficits of the acoustic startle response in rats.” Psychopharmacology (Berl) 232, no. 16 (August 2015): 3009–17. https://doi.org/10.1007/s00213-015-3940-z.Full Text Link to Item
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Slotkin, Theodore A., Samantha Skavicus, Jennifer Card, Edward D. Levin, and Frederic J. Seidler. “Amelioration strategies fail to prevent tobacco smoke effects on neurodifferentiation: Nicotinic receptor blockade, antioxidants, methyl donors.” Toxicology 333 (July 3, 2015): 63–75. https://doi.org/10.1016/j.tox.2015.04.005.Full Text Link to Item
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Crosby, Emily B., Jordan M. Bailey, Anthony N. Oliveri, and Edward D. Levin. “Neurobehavioral impairments caused by developmental imidacloprid exposure in zebrafish.” Neurotoxicol Teratol 49 (May 2015): 81–90. https://doi.org/10.1016/j.ntt.2015.04.006.Full Text Link to Item
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Bailey, J. M., A. N. Oliveri, C. Zhang, J. M. Frazier, S. Mackinnon, G. J. Cole, and E. D. Levin. “Long-term behavioral impairment following acute embryonic ethanol exposure in zebrafish.” Neurotoxicol Teratol 48 (March 2015): 1–8. https://doi.org/10.1016/j.ntt.2015.01.005.Full Text Link to Item
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Hall, Brandon J., Susan Slade, Corinne Wells, Jed E. Rose, and Edward D. Levin. “Bupropion-varenicline interactions and nicotine self-administration behavior in rats.” Pharmacol Biochem Behav 130 (March 2015): 84–89. https://doi.org/10.1016/j.pbb.2015.01.009.Full Text Link to Item
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Slotkin, Theodore A., Samantha Skavicus, Edward D. Levin, and Frederic J. Seidler. “Prenatal nicotine changes the response to postnatal chlorpyrifos: Interactions targeting serotonergic synaptic function and cognition.” Brain Res Bull 111 (February 2015): 84–96. https://doi.org/10.1016/j.brainresbull.2015.01.003.Full Text Link to Item
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Rezvani, A. H., E. D. Levin, M. P. Arolfo, C. Wells, M. Graupe, and I. Diamond. “Inhibition of aldehyde dehydrogenase-2 (ALDH-2) suppresses nicotine self-administration in rats.” Journal of Drug and Alcohol Research 4 (January 1, 2015). https://doi.org/10.4303/jdar/235940.Full Text
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Levin, Edward D., Brandon J. Hall, and Amir H. Rezvani. “Heterogeneity across brain regions and neurotransmitter interactions with nicotinic effects on memory function.” Curr Top Behav Neurosci 23 (2015): 87–101. https://doi.org/10.1007/978-3-319-13665-3_4.Full Text Link to Item
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Burke, Dennis A., Pooneh Heshmati, Ehsan Kholdebarin, and Edward D. Levin. “Decreasing nicotinic receptor activity and the spatial learning impairment caused by the NMDA glutamate antagonist dizocilpine in rats.” Eur J Pharmacol 741 (October 15, 2014): 132–39. https://doi.org/10.1016/j.ejphar.2014.07.030.Full Text Link to Item
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Cousins, Vanessa, Jed E. Rose, and Edward D. Levin. “IV nicotine self-administration in rats using a consummatory operant licking response: sensitivity to serotonergic, glutaminergic and histaminergic drugs.” Prog Neuropsychopharmacol Biol Psychiatry 54 (October 3, 2014): 200–205. https://doi.org/10.1016/j.pnpbp.2014.06.004.Full Text Link to Item
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Rezvani, Amir H., Marty C. Cauley, and Edward D. Levin. “Lorcaserin, a selective 5-HT(2C) receptor agonist, decreases alcohol intake in female alcohol preferring rats.” Pharmacol Biochem Behav 125 (October 2014): 8–14. https://doi.org/10.1016/j.pbb.2014.07.017.Full Text Link to Item
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Levin, Edward D., Ian Hao, Dennis A. Burke, Marty Cauley, Brandon J. Hall, and Amir H. Rezvani. “Effects of tobacco smoke constituents, anabasine and anatabine, on memory and attention in female rats.” J Psychopharmacol 28, no. 10 (October 2014): 915–22. https://doi.org/10.1177/0269881114543721.Full Text Link to Item
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Slotkin, Theodore A., Jennifer Card, Ashley Stadler, Edward D. Levin, and Frederic J. Seidler. “Effects of tobacco smoke on PC12 cell neurodifferentiation are distinct from those of nicotine or benzo[a]pyrene.” Neurotoxicol Teratol 43 (May 2014): 19–24. https://doi.org/10.1016/j.ntt.2014.03.002.Full Text Link to Item
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Hall, Brandon J., Corinne Wells, Cheyenne Allenby, Mung Yan Lin, Ian Hao, Lindsey Marshall, Jed E. Rose, and Edward D. Levin. “Differential effects of non-nicotine tobacco constituent compounds on nicotine self-administration in rats.” Pharmacol Biochem Behav 120 (May 2014): 103–8. https://doi.org/10.1016/j.pbb.2014.02.011.Full Text Link to Item
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Larrauri, José A., Lisalynn D. Kelley, Mason R. Jenkins, Eric C. Westman, Nestor A. Schmajuk, M Zachary Rosenthal, and Edward D. Levin. “Meclizine enhancement of sensorimotor gating in healthy male subjects with high startle responses and low prepulse inhibition.” Neuropsychopharmacology 39, no. 3 (February 2014): 651–59. https://doi.org/10.1038/npp.2013.248.Full Text Link to Item
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Levin, Edward D. “Nicotinic attention-deficit/hyperactivity disorder treatment.” Biol Psychiatry 75, no. 3 (February 1, 2014): 174. https://doi.org/10.1016/j.biopsych.2013.11.024.Full Text Link to Item
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Levin, Edward D., Marty Cauley, Joshua E. Johnson, Ellen M. Cooper, Heather M. Stapleton, P Lee Ferguson, Frederic J. Seidler, and Theodore A. Slotkin. “Prenatal dexamethasone augments the neurobehavioral teratology of chlorpyrifos: significance for maternal stress and preterm labor.” Neurotoxicol Teratol 41 (January 2014): 35–42. https://doi.org/10.1016/j.ntt.2013.10.004.Full Text Link to Item
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Yenugonda, Venkata M., Yingxian Xiao, Edward D. Levin, Amir H. Rezvani, Thao Tran, Nour Al-Muhtasib, Niaz Sahibzada, et al. “Design, synthesis and discovery of picomolar selective α4β2 nicotinic acetylcholine receptor ligands.” J Med Chem 56, no. 21 (November 14, 2013): 8404–21. https://doi.org/10.1021/jm4008455.Full Text Link to Item
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Kutlu, Munir G., Dennis Burke, Susan Slade, Brandon J. Hall, Jed E. Rose, and Edward D. Levin. “Role of insular cortex D₁ and D₂ dopamine receptors in nicotine self-administration in rats.” Behav Brain Res 256 (November 1, 2013): 273–78. https://doi.org/10.1016/j.bbr.2013.08.005.Full Text Link to Item
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Levin, Edward D. “Complex relationships of nicotinic receptor actions and cognitive functions.” Biochem Pharmacol 86, no. 8 (October 15, 2013): 1145–52. https://doi.org/10.1016/j.bcp.2013.07.021.Full Text Link to Item
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Levin, Edward D., Hannah G. Sexton, Karen Gordon, Christopher J. Gordon, Yingxian Xiao, Kenneth J. Kellar, Venkata Mahidhar Yenugonda, et al. “Effects of the sazetidine-a family of compounds on the body temperature in wildtype, nicotinic receptor β2-/- and α7-/- mice.” Eur J Pharmacol 718, no. 1–3 (October 15, 2013): 167–72. https://doi.org/10.1016/j.ejphar.2013.08.037.Full Text Link to Item
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Rezvani, Amir H., Hannah G. Sexton, Joshua Johnson, Cori Wells, Karen Gordon, and Edward D. Levin. “Effects of caffeine on alcohol consumption and nicotine self-administration in rats.” Alcohol Clin Exp Res 37, no. 9 (September 2013): 1609–17. https://doi.org/10.1111/acer.12127.Full Text Link to Item
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Liu, Yong, Janell Richardson, Thao Tran, Nour Al-Muhtasib, Teresa Xie, Venkata Mahidhar Yenugonda, Hannah G. Sexton, et al. “Chemistry and pharmacological studies of 3-alkoxy-2,5-disubstituted-pyridinyl compounds as novel selective α4β2 nicotinic acetylcholine receptor ligands that reduce alcohol intake in rats.” J Med Chem 56, no. 7 (April 11, 2013): 3000–3011. https://doi.org/10.1021/jm4000374.Full Text Link to Item
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Rezvani, Amir H., Marty Cauley, Yingxian Xiao, Kenneth J. Kellar, and Edward D. Levin. “Effects of chronic sazetidine-A, a selective α4β2 neuronal nicotinic acetylcholine receptors desensitizing agent on pharmacologically-induced impaired attention in rats.” Psychopharmacology (Berl) 226, no. 1 (March 2013): 35–43. https://doi.org/10.1007/s00213-012-2895-6.Full Text Link to Item
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Bailey, Jordan, Anthony Oliveri, and Edward D. Levin. “Zebrafish model systems for developmental neurobehavioral toxicology.” Birth Defects Res C Embryo Today 99, no. 1 (March 2013): 14–23. https://doi.org/10.1002/bdrc.21027.Full Text Link to Item
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Levin, Edward D., Marty Cauley, and Amir H. Rezvani. “Improvement of attentional function with antagonism of nicotinic receptors in female rats.” Eur J Pharmacol 702, no. 1–3 (February 28, 2013): 269–74. https://doi.org/10.1016/j.ejphar.2013.01.056.Full Text Link to Item
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Coppola, Anna, Brett R. Wenner, Olga Ilkayeva, Robert D. Stevens, Mauro Maggioni, Theodore A. Slotkin, Edward D. Levin, and Christopher B. Newgard. “Branched-chain amino acids alter neurobehavioral function in rats.” Am J Physiol Endocrinol Metab 304, no. 4 (February 15, 2013): E405–13. https://doi.org/10.1152/ajpendo.00373.2012.Full Text Link to Item
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Behl, Mamta, Deepa Rao, Kjersti Aagaard, Terry L. Davidson, Edward D. Levin, Theodore A. Slotkin, Supriya Srinivasan, et al. “Evaluation of the association between maternal smoking, childhood obesity, and metabolic disorders: a national toxicology program workshop review.” Environ Health Perspect 121, no. 2 (February 2013): 170–80. https://doi.org/10.1289/ehp.1205404.Full Text Link to Item
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Risher, Mary-Louise, Rebekah L. Fleming, Nathalie Boutros, Svetlana Semenova, Wilkie A. Wilson, Edward D. Levin, Athina Markou, H Scott Swartzwelder, and Shawn K. Acheson. “Long-term effects of chronic intermittent ethanol exposure in adolescent and adult rats: radial-arm maze performance and operant food reinforced responding.” Plos One 8, no. 5 (2013): e62940. https://doi.org/10.1371/journal.pone.0062940.Full Text Link to Item
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Hussmann, G Patrick, Jill R. Turner, Ermelinda Lomazzo, Rashmi Venkatesh, Vanessa Cousins, Yingxian Xiao, Robert P. Yasuda, et al. “Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain.” J Pharmacol Exp Ther 343, no. 2 (November 2012): 441–50. https://doi.org/10.1124/jpet.112.198085.Full Text Link to Item
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Roy, Nicole M., Brianna Arpie, Joseph Lugo, Elwood Linney, Edward D. Levin, and Daniel Cerutti. “Brief embryonic strychnine exposure in zebrafish causes long-term adult behavioral impairment with indications of embryonic synaptic changes.” Neurotoxicol Teratol 34, no. 6 (November 2012): 587–91. https://doi.org/10.1016/j.ntt.2012.08.001.Full Text Link to Item
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Swartzwelder, Nicholas A., M Louise Risher, Sabri H. Abdelwahab, Anouska D’Abo, Amir H. Rezvani, Edward D. Levin, Wilkie A. Wilson, H Scott Swartzwelder, and Shawn K. Acheson. “Effects of ethanol, Δ(9)-tetrahydrocannabinol, or their combination on object recognition memory and object preference in adolescent and adult male rats.” Neurosci Lett 527, no. 1 (October 3, 2012): 11–15. https://doi.org/10.1016/j.neulet.2012.08.037.Full Text Link to Item
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Rezvani, Amir H., Marty C. Cauley, Edwin C. Johnson, Gregory J. Gatto, and Edward D. Levin. “Effects of AZD3480, a neuronal nicotinic acetylcholine receptor agonist, and donepezil on dizocilpine-induced attentional impairment in rats.” Psychopharmacology (Berl) 223, no. 3 (October 2012): 251–58. https://doi.org/10.1007/s00213-012-2712-2.Full Text Link to Item
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Rezvani, Amir H., Andrew J. Lawrence, Maria P. Arolfo, Edward D. Levin, and David H. Overstreet. “Novel medication targets for the treatment of alcoholism: preclinical studies.” Recent Pat Cns Drug Discov 7, no. 2 (August 2012): 151–62. https://doi.org/10.2174/157488912800673182.Full Text Link to Item
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Johnson, Joshua E., Susan Slade, Corinne Wells, Ann Petro, Hannah Sexton, Amir H. Rezvani, Milton L. Brown, et al. “Assessing the effects of chronic sazetidine-A delivery on nicotine self-administration in both male and female rats.” Psychopharmacology (Berl) 222, no. 2 (July 2012): 269–76. https://doi.org/10.1007/s00213-012-2642-z.Full Text Link to Item
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Larrauri, José A., and Edward D. Levin. “Differential effects of the antidepressant mirtazapine on amphetamine- and dizocilpine-induced PPI deficits.” Pharmacol Biochem Behav 102, no. 1 (July 2012): 82–87. https://doi.org/10.1016/j.pbb.2012.03.010.Full Text Link to Item
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Rezvani, Amir H., Olga Timofeeva, Hannah G. Sexton, Damien DeCuir, Yingxian Xiao, Christopher J. Gordon, Kenneth J. Kellar, and Edward D. Levin. “Effects of sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, on body temperature regulation in mice and rats.” Eur J Pharmacol 682, no. 1–3 (May 5, 2012): 110–17. https://doi.org/10.1016/j.ejphar.2012.02.031.Full Text Link to Item
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Levin, Edward D. “α7-Nicotinic receptors and cognition.” Curr Drug Targets 13, no. 5 (May 2012): 602–6. https://doi.org/10.2174/138945012800398937.Full Text Link to Item
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Hall, F Scott, Athina Markou, Edward D. Levin, and George R. Uhl. “Mouse models for studying genetic influences on factors determining smoking cessation success in humans.” Ann N Y Acad Sci 1248 (February 2012): 39–70. https://doi.org/10.1111/j.1749-6632.2011.06415.x.Full Text Link to Item
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Newhouse, P., K. Kellar, P. Aisen, H. White, K. Wesnes, E. Coderre, A. Pfaff, H. Wilkins, D. Howard, and E. D. Levin. “Nicotine treatment of mild cognitive impairment: a 6-month double-blind pilot clinical trial.” Neurology 78, no. 2 (January 10, 2012): 91–101. https://doi.org/10.1212/WNL.0b013e31823efcbb.Full Text Link to Item
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Larrauri, J. A., M. Z. Rosenthal, E. D. Levin, F. J. McClernon, and N. A. Schmajuk. “Effects of unexpected changes in visual scenes on the human acoustic startle response and prepulse inhibition.” Behav Processes 89, no. 1 (January 2012): 1–7. https://doi.org/10.1016/j.beproc.2011.09.011.Full Text Link to Item
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Larrauri, José A., and Edward D. Levin. “The α₂-adrenergic antagonist idazoxan counteracts prepulse inhibition deficits caused by amphetamine or dizocilpine in rats.” Psychopharmacology (Berl) 219, no. 1 (January 2012): 99–108. https://doi.org/10.1007/s00213-011-2377-2.Full Text Link to Item
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Levin, Edward D., Susan Slade, Corinne Wells, Marty Cauley, Ann Petro, Analise Vendittelli, Michael Johnson, Paul Williams, Kofi Horton, and Amir H. Rezvani. “Threshold of adulthood for the onset of nicotine self-administration in male and female rats.” Behav Brain Res 225, no. 2 (December 1, 2011): 473–81. https://doi.org/10.1016/j.bbr.2011.08.005.Full Text Link to Item
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Timofeeva, O. A., and E. D. Levin. “Glutamate and nicotinic receptor interactions in working memory: importance for the cognitive impairment of schizophrenia.” Neuroscience 195 (November 10, 2011): 21–36. https://doi.org/10.1016/j.neuroscience.2011.08.038.Full Text Link to Item
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Levin, Edward D., and Robert L. Tanguay. “Introduction to zebrafish: current discoveries and emerging technologies for neurobehavioral toxicology and teratology.” Neurotoxicol Teratol 33, no. 6 (November 2011): 607. https://doi.org/10.1016/j.ntt.2011.10.005.Full Text Link to Item
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Levin, Edward D., Damiyon Sledge, Stephanie Roach, Ann Petro, Susan Donerly, and Elwood Linney. “Persistent behavioral impairment caused by embryonic methylphenidate exposure in zebrafish.” Neurotoxicol Teratol 33, no. 6 (November 2011): 668–73. https://doi.org/10.1016/j.ntt.2011.06.004.Full Text Link to Item
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Sledge, Damiyon, Jerry Yen, Terrell Morton, Laura Dishaw, Ann Petro, Susan Donerly, Elwood Linney, and Edward D. Levin. “Critical duration of exposure for developmental chlorpyrifos-induced neurobehavioral toxicity.” Neurotoxicol Teratol 33, no. 6 (November 2011): 742–51. https://doi.org/10.1016/j.ntt.2011.06.005.Full Text Link to Item
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Yen, Jerry, Sue Donerly, Edward D. Levin, and Elwood A. Linney. “Differential acetylcholinesterase inhibition of chlorpyrifos, diazinon and parathion in larval zebrafish.” Neurotoxicol Teratol 33, no. 6 (November 2011): 735–41. https://doi.org/10.1016/j.ntt.2011.10.004.Full Text Link to Item
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Levin, Edward D. “Using zebrafish to fill the gap between in vitro and rodent models for nicotinic drug development.” Biochemical Pharmacology 82, no. 8 (October 2011): 1038–39. https://doi.org/10.1016/j.bcp.2011.07.040.Full Text
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Rezvani, Amir H., Marty Cauley, Edwin Johnson, and Edward D. Levin. “Attentional improvement in rats with the nicotinic agonist AZ12564698 (AZD3480).” Biochemical Pharmacology 82, no. 8 (October 2011): 1040–41. https://doi.org/10.1016/j.bcp.2011.07.046.Full Text
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Cippitelli, Andrea, Amir H. Rezvani, J Elliott Robinson, Lindsay Eisenberg, Edward D. Levin, Pascal Bonaventure, S Timothy Motley, Timothy W. Lovenberg, Markus Heilig, and Annika Thorsell. “The novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist, JNJ-31020028, tested in animal models of alcohol consumption, relapse, and anxiety.” Alcohol 45, no. 6 (September 2011): 567–76. https://doi.org/10.1016/j.alcohol.2010.09.003.Full Text Link to Item
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Levin, Edward D., Joshua E. Johnson, Susan Slade, Corinne Wells, Marty Cauley, Ann Petro, and Jed E. Rose. “Lorcaserin, a 5-HT2C agonist, decreases nicotine self-administration in female rats.” J Pharmacol Exp Ther 338, no. 3 (September 2011): 890–96. https://doi.org/10.1124/jpet.111.183525.Full Text Link to Item
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Levin, Edward D., Philip J. Bushnell, and Amir H. Rezvani. “Attention-modulating effects of cognitive enhancers.” Pharmacol Biochem Behav 99, no. 2 (August 2011): 146–54. https://doi.org/10.1016/j.pbb.2011.02.008.Full Text Link to Item
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Rezvani, Amir H., Marty Cauley, Hannah Sexton, Yingxian Xiao, Milton L. Brown, Mikell A. Paige, Brian E. McDowell, Kenneth J. Kellar, and Edward D. Levin. “Sazetidine-A, a selective α4β2 nicotinic acetylcholine receptor ligand: effects on dizocilpine and scopolamine-induced attentional impairments in female Sprague-Dawley rats.” Psychopharmacology (Berl) 215, no. 4 (June 2011): 621–30. https://doi.org/10.1007/s00213-010-2161-8.Full Text Link to Item
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Schramm-Sapyta, Nicole L., Marty C. Cauley, Dalene K. Stangl, Susan Glowacz, K Amy Stepp, Edward D. Levin, and Cynthia M. Kuhn. “Role of individual and developmental differences in voluntary cocaine intake in rats.” Psychopharmacology (Berl) 215, no. 3 (June 2011): 493–504. https://doi.org/10.1007/s00213-011-2216-5.Full Text Link to Item
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Galici, Ruggero, Amir H. Rezvani, Leah Aluisio, Brian Lord, Edward D. Levin, Ian Fraser, Jamin Boggs, et al. “JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.” Psychopharmacology (Berl) 214, no. 4 (April 2011): 829–41. https://doi.org/10.1007/s00213-010-2092-4.Full Text Link to Item
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Levin, Edward D., Susan Slade, Corinne Wells, Ann Petro, and Jed E. Rose. “D-cycloserine selectively decreases nicotine self-administration in rats with low baseline levels of response.” Pharmacol Biochem Behav 98, no. 2 (April 2011): 210–14. https://doi.org/10.1016/j.pbb.2010.12.023.Full Text Link to Item
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Powers, Christina M., Edward D. Levin, Frederic J. Seidler, and Theodore A. Slotkin. “Silver exposure in developing zebrafish produces persistent synaptic and behavioral changes.” Neurotoxicol Teratol 33, no. 2 (March 2011): 329–32. https://doi.org/10.1016/j.ntt.2010.10.006.Full Text Link to Item
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Levin, Edward D., Susan Slade, Corinne Wells, Margaret Pruitt, Vanessa Cousins, Marty Cauley, Ann Petro, Dawn Hampton, and Jed Rose. “Histamine H(1) antagonist treatment with pyrilamine reduces nicotine self-administration in rats.” Eur J Pharmacol 650, no. 1 (January 10, 2011): 256–60. https://doi.org/10.1016/j.ejphar.2010.10.013.Full Text Link to Item
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Levin, E. D. “Nicotinic receptor systems and neurobehavioral function in zebrafish.” Neuromethods 52 (January 1, 2011): 89–100. https://doi.org/10.1007/978-1-60761-922-2_4.Full Text
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Levin, Edward D. “Zebrafish assessment of cognitive improvement and anxiolysis: filling the gap between in vitro and rodent models for drug development.” Rev Neurosci 22, no. 1 (2011): 75–84. https://doi.org/10.1515/RNS.2011.009.Full Text Link to Item
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Levin, Edward D., Dawn Hampton, and Jed E. Rose. “IV nicotine self-administration in rats using the consummatory operant licking response.” Physiol Behav 101, no. 5 (December 2, 2010): 755–58. https://doi.org/10.1016/j.physbeh.2010.08.016.Full Text Link to Item
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Larrauri, José A., and Edward D. Levin. “PPI deficit induced by amphetamine is attenuated by the histamine H1 antagonist pyrilamine, but is exacerbated by the serotonin 5-HT2 antagonist ketanserin.” Psychopharmacology (Berl) 212, no. 4 (December 2010): 551–58. https://doi.org/10.1007/s00213-010-2005-6.Full Text Link to Item
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Timofeeva, O. A., and E. D. Levin. “Lasting Behavioral Consequences of Organophosphate Pesticide Exposure During Development,” December 1, 2010, 837–46. https://doi.org/10.1016/B978-0-12-374367-1.00033-1.Full Text
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Aschner, Michael, Edward D. Levin, Cristina Suñol, James O. Olopade, Kirsten J. Helmcke, Daiana S. Avila, Damiyon Sledge, et al. “Gene-environment interactions: neurodegeneration in non-mammals and mammals.” Neurotoxicology 31, no. 5 (September 2010): 582–88. https://doi.org/10.1016/j.neuro.2010.03.008.Full Text Link to Item
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Rezvani, Amir H., Susan Slade, Cori Wells, Ann Petro, Lawrence Lumeng, Ting-Kai Li, Yingxian Xiao, et al. “Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats.” Psychopharmacology (Berl) 211, no. 2 (August 2010): 161–74. https://doi.org/10.1007/s00213-010-1878-8.Full Text Link to Item
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Rezvani, Amir H., Hannah Sexton, and Edward D. Levin. “Persistent high alcohol consumption in alcohol-preferring (P) rats results from a lack of normal aversion to alcohol.” Alcohol Alcohol 45, no. 3 (May 2010): 219–22. https://doi.org/10.1093/alcalc/agq020.Full Text Link to Item
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Adigun, Abayomi A., Nicola Wrench, Edward D. Levin, Frederic J. Seidler, and Theodore A. Slotkin. “Neonatal parathion exposure and interactions with a high-fat diet in adulthood: Adenylyl cyclase-mediated cell signaling in heart, liver and cerebellum.” Brain Res Bull 81, no. 6 (April 5, 2010): 605–12. https://doi.org/10.1016/j.brainresbull.2010.01.003.Full Text Link to Item
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Levin, Edward D., Olga A. Timofeeva, Liwei Yang, Ann Petro, Ian T. Ryde, Nicola Wrench, Frederic J. Seidler, and Theodore A. Slotkin. “Early postnatal parathion exposure in rats causes sex-selective cognitive impairment and neurotransmitter defects which emerge in aging.” Behav Brain Res 208, no. 2 (April 2, 2010): 319–27. https://doi.org/10.1016/j.bbr.2009.11.007.Full Text Link to Item
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Sanders, D., D. Simkiss, D. Braddy, S. Baccus, T. Morton, R. Cannady, N. Weaver, J. E. Rose, and E. D. Levin. “Nicotinic receptors in the habenula: importance for memory.” Neuroscience 166, no. 2 (March 17, 2010): 386–90. https://doi.org/10.1016/j.neuroscience.2009.12.035.Full Text Link to Item
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Levin, Edward D., Amir H. Rezvani, Yingxian Xiao, Susan Slade, Marty Cauley, Corinne Wells, Dawn Hampton, et al. “Sazetidine-A, a selective alpha4beta2 nicotinic receptor desensitizing agent and partial agonist, reduces nicotine self-administration in rats.” J Pharmacol Exp Ther 332, no. 3 (March 2010): 933–39. https://doi.org/10.1124/jpet.109.162073.Full Text Link to Item
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Lassiter, T Leon, Ian T. Ryde, Edward D. Levin, Frederic J. Seidler, and Theodore A. Slotkin. “Neonatal exposure to parathion alters lipid metabolism in adulthood: Interactions with dietary fat intake and implications for neurodevelopmental deficits.” Brain Res Bull 81, no. 1 (January 15, 2010): 85–91. https://doi.org/10.1016/j.brainresbull.2009.07.002.Full Text Link to Item
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Timofeeva, Olga A., Donnie Eddins, Jerrel L. Yakel, Perry J. Blackshear, and Edward D. Levin. “Hippocampal infusions of MARCKS peptides impair memory of rats on the radial-arm maze.” Brain Res 1308 (January 13, 2010): 147–52. https://doi.org/10.1016/j.brainres.2009.10.040.Full Text Link to Item
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Aschner, M., K. M. Crofton, and E. D. Levin. “Introduction to the special issue on emerging high throughput and complementary model screens for neurotoxicology.” Neurotoxicol Teratol 32, no. 1 (January 2010): 1–3. https://doi.org/10.1016/j.ntt.2009.08.006.Full Text Link to Item
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Eddins, Donnie, Daniel Cerutti, Paul Williams, Elwood Linney, and Edward D. Levin. “Zebrafish provide a sensitive model of persisting neurobehavioral effects of developmental chlorpyrifos exposure: comparison with nicotine and pilocarpine effects and relationship to dopamine deficits.” Neurotoxicol Teratol 32, no. 1 (January 2010): 99–108. https://doi.org/10.1016/j.ntt.2009.02.005.Full Text Link to Item
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Bencan, Zachary, Damiyon Sledge, and Edward D. Levin. “Buspirone, chlordiazepoxide and diazepam effects in a zebrafish model of anxiety.” Pharmacol Biochem Behav 94, no. 1 (November 2009): 75–80. https://doi.org/10.1016/j.pbb.2009.07.009.Full Text Link to Item
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Slotkin, Theodore A., Nicola Wrench, Ian T. Ryde, T Leon Lassiter, Edward D. Levin, and Frederic J. Seidler. “Neonatal parathion exposure disrupts serotonin and dopamine synaptic function in rat brain regions: modulation by a high-fat diet in adulthood.” Neurotoxicol Teratol 31, no. 6 (November 2009): 390–99. https://doi.org/10.1016/j.ntt.2009.07.003.Full Text Link to Item
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Cannady, Reginald, Ruth Weir, Boyoung Wee, Emily Gotschlich, Nadeem Kolia, Edward Lau, Jesse Brotherton, and Edward D. Levin. “Nicotinic antagonist effects in the mediodorsal thalamic nucleus: regional heterogeneity of nicotinic receptor involvement in cognitive function.” Biochem Pharmacol 78, no. 7 (October 1, 2009): 788–94. https://doi.org/10.1016/j.bcp.2009.05.021.Full Text Link to Item
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Levin, Edward D., Michael Aschner, Ulrike Heberlein, Douglas Ruden, Kathleen A. Welsh-Bohmer, Selena Bartlett, Karen Berger, et al. “Genetic aspects of behavioral neurotoxicology.” Neurotoxicology 30, no. 5 (September 2009): 741–53. https://doi.org/10.1016/j.neuro.2009.07.014.Full Text Link to Item
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Schramm-Sapyta, Nicole L., Q David Walker, Joseph M. Caster, Edward D. Levin, and Cynthia M. Kuhn. “Are adolescents more vulnerable to drug addiction than adults? Evidence from animal models.” Psychopharmacology (Berl) 206, no. 1 (September 2009): 1–21. https://doi.org/10.1007/s00213-009-1585-5.Full Text Link to Item
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Noyes, Pamela D., Matthew K. McElwee, Hilary D. Miller, Bryan W. Clark, Lindsey A. Van Tiem, Kia C. Walcott, Kyle N. Erwin, and Edward D. Levin. “The toxicology of climate change: environmental contaminants in a warming world.” Environ Int 35, no. 6 (August 2009): 971–86. https://doi.org/10.1016/j.envint.2009.02.006.Full Text Open Access Copy Link to Item
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Rezvani, Amir H., David H. Overstreet, Anil H. Vaidya, Boyu Zhao, and Edward D. Levin. “Carisbamate, a novel antiepileptic candidate compound, attenuates alcohol intake in alcohol-preferring rats.” Alcohol Clin Exp Res 33, no. 8 (August 2009): 1366–73. https://doi.org/10.1111/j.1530-0277.2009.00966.x.Full Text Link to Item
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Slotkin, Theodore A., T Leon Lassiter, Ian T. Ryde, Nicola Wrench, Edward D. Levin, and Frederic J. Seidler. “Consumption of a high-fat diet in adulthood ameliorates the effects of neonatal parathion exposure on acetylcholine systems in rat brain regions.” Environ Health Perspect 117, no. 6 (June 2009): 916–22. https://doi.org/10.1289/ehp.0800459.Full Text Link to Item
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Eddins, Donnie, Rebecca C. Klein, Jerrel L. Yakel, and Edward D. Levin. “Hippocampal infusions of apolipoprotein E peptides induce long-lasting cognitive impairment.” Brain Res Bull 79, no. 2 (April 29, 2009): 111–15. https://doi.org/10.1016/j.brainresbull.2009.01.003.Full Text Link to Item
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Levin, Edward D., Abigail Perkins, Terrell Brotherton, Melissa Qazi, Chantal Berez, Janitza Montalvo-Ortiz, Kasey Davis, Paul Williams, and N Channelle Christopher. “Chronic underactivity of medial frontal cortical beta2-containing nicotinic receptors increases clozapine-induced working memory impairment in female rats.” Prog Neuropsychopharmacol Biol Psychiatry 33, no. 2 (March 17, 2009): 296–302. https://doi.org/10.1016/j.pnpbp.2008.12.003.Full Text Link to Item
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Rezvani, Amir H., Ehsan Kholdebarin, Frederic H. Brucato, Patrick M. Callahan, David A. Lowe, and Edward D. Levin. “Effect of R3487/MEM3454, a novel nicotinic alpha7 receptor partial agonist and 5-HT3 antagonist on sustained attention in rats.” Prog Neuropsychopharmacol Biol Psychiatry 33, no. 2 (March 17, 2009): 269–75. https://doi.org/10.1016/j.pnpbp.2008.11.018.Full Text Link to Item
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Rezvani, Amir H., Ehsan Kholdebarin, Marty C. Cauley, Elizabeth Dawson, and Edward D. Levin. “Attenuation of pharmacologically-induced attentional impairment by methylphenidate in rats.” Pharmacol Biochem Behav 92, no. 1 (March 2009): 141–46. https://doi.org/10.1016/j.pbb.2008.11.005.Full Text Link to Item
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Schmajuk, N. A., J. A. Larrauri, L. G. De la Casa, and E. D. Levin. “Attenuation of auditory startle and prepulse inhibition by unexpected changes in ambient illumination through dopaminergic mechanisms.” Behav Brain Res 197, no. 2 (February 11, 2009): 251–61. https://doi.org/10.1016/j.bbr.2008.08.030.Full Text Link to Item
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Levin, Edward D., Ann Petro, Amir H. Rezvani, Ninitia Pollard, N Channelle Christopher, Mariel Strauss, Jessica Avery, Jessica Nicholson, and Jed E. Rose. “Nicotinic alpha7- or beta2-containing receptor knockout: effects on radial-arm maze learning and long-term nicotine consumption in mice.” Behav Brain Res 196, no. 2 (January 23, 2009): 207–13. https://doi.org/10.1016/j.bbr.2008.08.048.Full Text Link to Item
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Eddins, Donnie, Ann Petro, Paul Williams, Daniel T. Cerutti, and Edward D. Levin. “Nicotine effects on learning in zebrafish: the role of dopaminergic systems.” Psychopharmacology (Berl) 202, no. 1–3 (January 2009): 103–9. https://doi.org/10.1007/s00213-008-1287-4.Full Text Link to Item
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Slotkin, Theodore A., Edward D. Levin, and Frederic J. Seidler. “Developmental neurotoxicity of parathion: progressive effects on serotonergic systems in adolescence and adulthood.” Neurotoxicol Teratol 31, no. 1 (January 2009): 11–17. https://doi.org/10.1016/j.ntt.2008.08.004.Full Text Link to Item
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Timofeeva, Olga A., David Sanders, Kristen Seemann, Liwei Yang, Daniel Hermanson, Sam Regenbogen, Samantha Agoos, et al. “Persistent behavioral alterations in rats neonatally exposed to low doses of the organophosphate pesticide, parathion.” Brain Res Bull 77, no. 6 (December 16, 2008): 404–11. https://doi.org/10.1016/j.brainresbull.2008.08.019.Full Text Link to Item
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Levin, Edward D., Susan Slade, Michael Johnson, Ann Petro, Kofi Horton, Paul Williams, Amir H. Rezvani, and Jed E. Rose. “Ketanserin, a 5-HT2 receptor antagonist, decreases nicotine self-administration in rats.” Eur J Pharmacol 600, no. 1–3 (December 14, 2008): 93–97. https://doi.org/10.1016/j.ejphar.2008.10.016.Full Text Link to Item
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Lassiter, T Leon, Ian T. Ryde, Emiko A. Mackillop, Kathleen K. Brown, Edward D. Levin, Frederic J. Seidler, and Theodore A. Slotkin. “Exposure of neonatal rats to parathion elicits sex-selective reprogramming of metabolism and alters the response to a high-fat diet in adulthood.” Environ Health Perspect 116, no. 11 (November 2008): 1456–62. https://doi.org/10.1289/ehp.11673.Full Text Link to Item
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Bencan, Zachary, and Edward D. Levin. “The role of alpha7 and alpha4beta2 nicotinic receptors in the nicotine-induced anxiolytic effect in zebrafish.” Physiol Behav 95, no. 3 (October 20, 2008): 408–12. https://doi.org/10.1016/j.physbeh.2008.07.009.Full Text Link to Item
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Slotkin, Theodore A., Bethany E. Bodwell, Ian T. Ryde, Edward D. Levin, and Frederic J. Seidler. “Exposure of neonatal rats to parathion elicits sex-selective impairment of acetylcholine systems in brain regions during adolescence and adulthood.” Environ Health Perspect 116, no. 10 (October 2008): 1308–14. https://doi.org/10.1289/ehp.11451.Full Text Link to Item
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Timofeeva, Olga A., and Edward D. Levin. “Idazoxan blocks the nicotine-induced reversal of the memory impairment caused by the NMDA glutamate receptor antagonist dizocilpine.” Pharmacol Biochem Behav 90, no. 3 (September 2008): 372–81. https://doi.org/10.1016/j.pbb.2008.03.011.Full Text Link to Item
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Crofton, Kevin M., John A. Foss, Ulla Hass, Karl F. Jensen, Edward D. Levin, and Sherry P. Parker. “Undertaking positive control studies as part of developmental neurotoxicity testing: a report from the ILSI Research Foundation/Risk Science Institute expert working group on neurodevelopmental endpoints.” Neurotoxicol Teratol 30, no. 4 (July 2008): 266–87. https://doi.org/10.1016/j.ntt.2007.06.002.Full Text Link to Item
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Rezvani, A. H., D. Eddins, S. Slade, D. S. Hampton, N. C. Christopher, A. Petro, K. Horton, M. Johnson, and E. D. Levin. “Neonatal 6-hydroxydopamine lesions of the frontal cortex in rats: persisting effects on locomotor activity, learning and nicotine self-administration.” Neuroscience 154, no. 3 (June 26, 2008): 885–97. https://doi.org/10.1016/j.neuroscience.2008.04.020.Full Text Link to Item
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Morey, Jeanine S., James C. Ryan, Marie-Yasmine Bottein Dechraoui, Amir H. Rezvani, Edward D. Levin, Christopher J. Gordon, John S. Ramsdell, and Frances M. Van Dolah. “Liver genomic responses to ciguatoxin: evidence for activation of phase I and phase II detoxification pathways following an acute hypothermic response in mice.” Toxicol Sci 103, no. 2 (June 2008): 298–310. https://doi.org/10.1093/toxsci/kfn055.Full Text Link to Item
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Rezvani, Amir H., Yousef Tizabi, Bruk Getachew, Sheketha R. Hauser, D Patrick Caldwell, Christopher Hunter, and Edward D. Levin. “Chronic nicotine and dizocilpine effects on nicotinic and NMDA glutamatergic receptor regulation: interactions with clozapine actions and attentional performance in rats.” Prog Neuropsychopharmacol Biol Psychiatry 32, no. 4 (May 15, 2008): 1030–40. https://doi.org/10.1016/j.pnpbp.2008.01.018.Full Text Link to Item
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West, Adrian K., Juan Hidalgo, Donnie Eddins, Edward D. Levin, and Michael Aschner. “Metallothionein in the central nervous system: Roles in protection, regeneration and cognition.” Neurotoxicology 29, no. 3 (May 2008): 489–503. https://doi.org/10.1016/j.neuro.2007.12.006.Full Text Link to Item
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Bottein Dechraoui, Marie-Yasmine, Amir H. Rezvani, Christopher J. Gordon, Edward D. Levin, and John S. Ramsdell. “Repeat exposure to ciguatoxin leads to enhanced and sustained thermoregulatory, pain threshold and motor activity responses in mice: relationship to blood ciguatoxin concentrations.” Toxicology 246, no. 1 (April 3, 2008): 55–62. https://doi.org/10.1016/j.tox.2007.12.013.Full Text Link to Item
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Slotkin, Theodore A., Ian T. Ryde, Edward D. Levin, and Frederic J. Seidler. “Developmental neurotoxicity of low dose diazinon exposure of neonatal rats: effects on serotonin systems in adolescence and adulthood.” Brain Res Bull 75, no. 5 (March 28, 2008): 640–47. https://doi.org/10.1016/j.brainresbull.2007.10.008.Full Text Link to Item
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Eddins, Donnie, Ann Petro, Ninitia Pollard, Jonathan H. Freedman, and Edward D. Levin. “Mercury-induced cognitive impairment in metallothionein-1/2 null mice.” Neurotoxicol Teratol 30, no. 2 (March 2008): 88–95. https://doi.org/10.1016/j.ntt.2007.12.005.Full Text Link to Item
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Slotkin, Theodore A., Bethany E. Bodwell, Edward D. Levin, and Frederic J. Seidler. “Neonatal exposure to low doses of diazinon: long-term effects on neural cell development and acetylcholine systems.” Environ Health Perspect 116, no. 3 (March 2008): 340–48. https://doi.org/10.1289/ehp.11005.Full Text Link to Item
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Rezvani, Amir H., Ehsan Kholdebarin, Elizabeth Dawson, and Edward D. Levin. “Nicotine and clozapine effects on attentional performance impaired by the NMDA antagonist dizocilpine in female rats.” Int J Neuropsychopharmacol 11, no. 1 (February 2008): 63–70. https://doi.org/10.1017/S1461145706007528.Full Text Link to Item
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Roegge, Cindy S., Olga A. Timofeeva, Frederic J. Seidler, Theodore A. Slotkin, and Edward D. Levin. “Developmental diazinon neurotoxicity in rats: later effects on emotional response.” Brain Res Bull 75, no. 1 (January 31, 2008): 166–72. https://doi.org/10.1016/j.brainresbull.2007.08.008.Full Text Link to Item
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Timofeeva, Olga A., Cindy S. Roegge, Frederic J. Seidler, Theodore A. Slotkin, and Edward D. Levin. “Persistent cognitive alterations in rats after early postnatal exposure to low doses of the organophosphate pesticide, diazinon.” Neurotoxicol Teratol 30, no. 1 (January 2008): 38–45. https://doi.org/10.1016/j.ntt.2007.10.002.Full Text Link to Item
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Ryan, James C., Marie-Yasmine Bottein Dechraoui, Jeanine S. Morey, Amir Rezvani, Edward D. Levin, Christopher J. Gordon, John S. Ramsdell, and Frances M. Van Dolah. “Transcriptional profiling of whole blood and serum protein analysis of mice exposed to the neurotoxin Pacific Ciguatoxin-1.” Neurotoxicology 28, no. 6 (November 2007): 1099–1109. https://doi.org/10.1016/j.neuro.2007.05.013.Full Text Link to Item
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Levin, Edward D., and Amir H. Rezvani. “Nicotinic interactions with antipsychotic drugs, models of schizophrenia and impacts on cognitive function.” Biochem Pharmacol 74, no. 8 (October 15, 2007): 1182–91. https://doi.org/10.1016/j.bcp.2007.07.019.Full Text Link to Item
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Kholdebarin, Ehsan, D Patrick Caldwell, W Paul Blackwelder, Margaret Kao, N Channelle Christopher, and Edward D. Levin. “Interaction of nicotinic and histamine H(3) systems in the radial-arm maze repeated acquisition task.” Eur J Pharmacol 569, no. 1–2 (August 13, 2007): 64–69. https://doi.org/10.1016/j.ejphar.2007.04.051.Full Text Link to Item
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Levin, Edward D., Susan Slade Lawrence, Ann Petro, Kofi Horton, Amir H. Rezvani, Frederic J. Seidler, and Theodore A. Slotkin. “Adolescent vs. adult-onset nicotine self-administration in male rats: duration of effect and differential nicotinic receptor correlates.” Neurotoxicol Teratol 29, no. 4 (July 2007): 458–65. https://doi.org/10.1016/j.ntt.2007.02.002.Full Text Link to Item
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Roegge, Cindy S., Charles Perraut, Xin Hao, and Edward D. Levin. “Histamine H1 receptor involvement in prepulse inhibition and memory function: relevance for the antipsychotic actions of clozapine.” Pharmacol Biochem Behav 86, no. 4 (April 2007): 686–92. https://doi.org/10.1016/j.pbb.2007.02.014.Full Text Link to Item
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Levin, Edward D., D Patrick Caldwell, and Charles Perraut. “Clozapine treatment reverses dizocilpine-induced deficits of pre-pulse inhibition of tactile startle response.” Pharmacol Biochem Behav 86, no. 3 (March 2007): 597–605. https://doi.org/10.1016/j.pbb.2007.02.005.Full Text Link to Item
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Matta, Shannon G., David J. Balfour, Neal L. Benowitz, R Thomas Boyd, Jerry J. Buccafusco, Anthony R. Caggiula, Caroline R. Craig, et al. “Guidelines on nicotine dose selection for in vivo research.” Psychopharmacology (Berl) 190, no. 3 (February 2007): 269–319. https://doi.org/10.1007/s00213-006-0441-0.Full Text Link to Item
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Levin, Edward D., Zachary Bencan, and Daniel T. Cerutti. “Anxiolytic effects of nicotine in zebrafish.” Physiol Behav 90, no. 1 (January 30, 2007): 54–58. https://doi.org/10.1016/j.physbeh.2006.08.026.Full Text Link to Item
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Rezvani, Amir H., David H. Overstreet, Edward D. Levin, Daniel I. Rosenthal, Cheryl P. Kordik, Allen B. Reitz, and Anil H. Vaidya. “Effects of atypical anxiolytic N-phenyl-2-[1-[3-(2-pyridinylethynyl)benzoyl]-4-piperidine]acetamide (JNJ-5234801) on alcohol intake in alcohol-preferring P rats.” Alcohol Clin Exp Res 31, no. 1 (January 2007): 57–63. https://doi.org/10.1111/j.1530-0277.2006.00264.x.Full Text Link to Item
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Levin, Edward D., Susan Lawrence, Ann Petro, Kofi Horton, Frederic J. Seidler, and Theodore A. Slotkin. “Increased nicotine self-administration following prenatal exposure in female rats.” Pharmacol Biochem Behav 85, no. 3 (November 2006): 669–74. https://doi.org/10.1016/j.pbb.2006.11.006.Full Text Link to Item
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Levin, Edward D., Wyki Gina Pang, Jerry Harrison, Paul Williams, Ann Petro, and John S. Ramsdell. “Persistent neurobehavioral effects of early postnatal domoic acid exposure in rats.” Neurotoxicol Teratol 28, no. 6 (November 2006): 673–80. https://doi.org/10.1016/j.ntt.2006.08.005.Full Text Link to Item
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McClernon, F Joseph, F Berry Hiott, Eric C. Westman, Jed E. Rose, and Edward D. Levin. “Transdermal nicotine attenuates depression symptoms in nonsmokers: a double-blind, placebo-controlled trial.” Psychopharmacology (Berl) 189, no. 1 (November 2006): 125–33. https://doi.org/10.1007/s00213-006-0516-y.Full Text Link to Item
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Pocivavsek, Ana, Laura Icenogle, and Edward D. Levin. “Ventral hippocampal alpha7 and alpha4beta2 nicotinic receptor blockade and clozapine effects on memory in female rats.” Psychopharmacology (Berl) 188, no. 4 (November 2006): 597–604. https://doi.org/10.1007/s00213-006-0416-1.Full Text Link to Item
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Slotkin, Theodore A., Charlotte A. Tate, Ian T. Ryde, Edward D. Levin, and Frederic J. Seidler. “Organophosphate insecticides target the serotonergic system in developing rat brain regions: disparate effects of diazinon and parathion at doses spanning the threshold for cholinesterase inhibition.” Environ Health Perspect 114, no. 10 (October 2006): 1542–46. https://doi.org/10.1289/ehp.9337.Full Text Link to Item
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Levin, Edward D., and D Patrick Caldwell. “Low-dose mecamylamine improves learning of rats in the radial-arm maze repeated acquisition procedure.” Neurobiol Learn Mem 86, no. 1 (July 2006): 117–22. https://doi.org/10.1016/j.nlm.2006.01.007.Full Text Link to Item
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Schmajuk, N. A., J. A. Larrauri, N. Hagenbuch, E. D. Levin, J. Feldon, and B. K. Yee. “Startle and prepulse inhibition as a function of background noise: a computational and experimental analysis.” Behav Brain Res 170, no. 2 (June 30, 2006): 182–96. https://doi.org/10.1016/j.bbr.2006.02.021.Full Text Link to Item
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Slotkin, Theodore A., Edward D. Levin, and Frederic J. Seidler. “Comparative developmental neurotoxicity of organophosphate insecticides: effects on brain development are separable from systemic toxicity.” Environ Health Perspect 114, no. 5 (May 2006): 746–51. https://doi.org/10.1289/ehp.8828.Full Text Link to Item
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Nott, Alexi, and Edward D. Levin. “Dorsal hippocampal alpha7 and alpha4beta2 nicotinic receptors and memory.” Brain Res 1081, no. 1 (April 7, 2006): 72–78. https://doi.org/10.1016/j.brainres.2006.01.052.Full Text Link to Item
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Levin, Edward D., Charles Perraut, Ninitia Pollard, and Jonathan H. Freedman. “Metallothionein expression and neurocognitive function in mice.” Physiol Behav 87, no. 3 (March 30, 2006): 513–18. https://doi.org/10.1016/j.physbeh.2005.11.014.Full Text Link to Item
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Levin, Edward D., F Joseph McClernon, and Amir H. Rezvani. “Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization.” Psychopharmacology (Berl) 184, no. 3–4 (March 2006): 523–39. https://doi.org/10.1007/s00213-005-0164-7.Full Text Link to Item
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Levin, Edward D., Joy Limpuangthip, Tara Rachakonda, and Miram Peterson. “Timing of nicotine effects on learning in zebrafish.” Psychopharmacology (Berl) 184, no. 3–4 (March 2006): 547–52. https://doi.org/10.1007/s00213-005-0162-9.Full Text Link to Item
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Levin, Edward D., and N Channelle Christopher. “Effects of clozapine on memory function in the rat neonatal hippocampal lesion model of schizophrenia.” Prog Neuropsychopharmacol Biol Psychiatry 30, no. 2 (March 2006): 223–29. https://doi.org/10.1016/j.pnpbp.2005.10.018.Full Text Link to Item
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Rezvani, Amir H., D Patrick Caldwell, and Edward D. Levin. “Chronic nicotine interactions with clozapine and risperidone and attentional function in rats.” Prog Neuropsychopharmacol Biol Psychiatry 30, no. 2 (March 2006): 190–97. https://doi.org/10.1016/j.pnpbp.2005.10.017.Full Text Link to Item
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Timme-Laragy, Alicia R., Edward D. Levin, and Richard T. Di Giulio. “Developmental and behavioral effects of embryonic exposure to the polybrominated diphenylether mixture DE-71 in the killifish (Fundulus heteroclitus).” Chemosphere 62, no. 7 (February 2006): 1097–1104. https://doi.org/10.1016/j.chemosphere.2005.05.037.Full Text Link to Item
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Levin, Edward D. “The rationale for studying transmitter interactions to understand the neural bases of cognitive function.” Exs 98 (2006): 1–3. https://doi.org/10.1007/978-3-7643-7772-4_1.Full Text Link to Item
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Levin, Edward D., and Amir H. Rezvani. “Nicotinic-antipsychotic drug interactions and cognitive function.” Exs 98 (2006): 185–205. https://doi.org/10.1007/978-3-7643-7772-4_10.Full Text Link to Item
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Levin, Edward, Laura Icenogle, and Ashkan Farzad. “Ketanserin attenuates nicotine-induced working memory improvement in rats.” Pharmacol Biochem Behav 82, no. 2 (October 2005): 289–92. https://doi.org/10.1016/j.pbb.2005.08.017.Full Text Link to Item
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Slikker, William, Z Alex Xu, Edward D. Levin, and Theodore A. Slotkin. “Mode of action: disruption of brain cell replication, second messenger, and neurotransmitter systems during development leading to cognitive dysfunction--developmental neurotoxicity of nicotine.” Crit Rev Toxicol 35, no. 8–9 (October 2005): 703–11. https://doi.org/10.1080/10408440591007421.Full Text Link to Item
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Barron, Susan, Aaron White, H Scott Swartzwelder, Richard L. Bell, Zachary A. Rodd, Craig J. Slawecki, Cindy L. Ehlers, Edward D. Levin, Amir H. Rezvani, and Linda P. Spear. “Adolescent vulnerabilities to chronic alcohol or nicotine exposure: findings from rodent models.” Alcohol Clin Exp Res 29, no. 9 (September 2005): 1720–25. https://doi.org/10.1097/01.alc.0000179220.79356.e5.Full Text Link to Item
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Kreider, Marisa L., Edward D. Levin, Frederic J. Seidler, and Theodore A. Slotkin. “Gestational dexamethasone treatment elicits sex-dependent alterations in locomotor activity, reward-based memory and hippocampal cholinergic function in adolescent and adult rats.” Neuropsychopharmacology 30, no. 9 (September 2005): 1617–23. https://doi.org/10.1038/sj.npp.1300716.Full Text Link to Item
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Levin, E. D. “Marine and freshwater toxin impacts on neurobehavioral function.” Neurotoxicology and Teratology 27, no. 5 (September 1, 2005): 693. https://doi.org/10.1016/j.ntt.2005.06.011.Full Text
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Levin, Edward D., Kristen Pizarro, Wyki Gina Pang, Jerry Harrison, and John S. Ramsdell. “Persisting behavioral consequences of prenatal domoic acid exposure in rats.” Neurotoxicol Teratol 27, no. 5 (September 2005): 719–25. https://doi.org/10.1016/j.ntt.2005.06.017.Full Text Link to Item
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Heindel, Jerrold J., and Edward Levin. “Developmental origins and environmental influences--Introduction. NIEHS symposium.” Birth Defects Res a Clin Mol Teratol 73, no. 7 (July 2005): 469. https://doi.org/10.1002/bdra.20141.Full Text Link to Item
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Levin, Edward D. “Fetal nicotinic overload, blunted sympathetic responsivity, and obesity.” Birth Defects Res a Clin Mol Teratol 73, no. 7 (July 2005): 481–84. https://doi.org/10.1002/bdra.20162.Full Text Link to Item
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Levin, Edward D., N Channelle Christopher, and James D. Crapo. “Memory decline of aging reduced by extracellular superoxide dismutase overexpression.” Behav Genet 35, no. 4 (July 2005): 447–53. https://doi.org/10.1007/s10519-004-1510-y.Full Text Link to Item
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Addy, Nii A., Ana Pocivavsek, and Edward D. Levin. “Reversal of clozapine effects on working memory in rats with fimbria-fornix lesions.” Neuropsychopharmacology 30, no. 6 (June 2005): 1121–27. https://doi.org/10.1038/sj.npp.1300669.Full Text Link to Item
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Aldridge, Justin E., Edward D. Levin, Frederic J. Seidler, and Theodore A. Slotkin. “Developmental exposure of rats to chlorpyrifos leads to behavioral alterations in adulthood, involving serotonergic mechanisms and resembling animal models of depression.” Environ Health Perspect 113, no. 5 (May 2005): 527–31. https://doi.org/10.1289/ehp.7867.Full Text Link to Item
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Levin, Edward D., Ann Petro, and Allison Beatty. “Olanzapine interactions with nicotine and mecamylamine in rats: effects on memory function.” Neurotoxicol Teratol 27, no. 3 (May 2005): 459–64. https://doi.org/10.1016/j.ntt.2005.01.011.Full Text Link to Item
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Levin, Edward D., Ann Petro, and D Patrick Caldwell. “Nicotine and clozapine actions on pre-pulse inhibition deficits caused by N-methyl-D-aspartate (NMDA) glutamatergic receptor blockade.” Prog Neuropsychopharmacol Biol Psychiatry 29, no. 4 (May 2005): 581–86. https://doi.org/10.1016/j.pnpbp.2005.01.012.Full Text Link to Item
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Rezvani, Amir H., D Patrick Caldwell, and Edward D. Levin. “Nicotinic-serotonergic drug interactions and attentional performance in rats.” Psychopharmacology (Berl) 179, no. 3 (May 2005): 521–28. https://doi.org/10.1007/s00213-004-2060-y.Full Text Link to Item
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Levin, Edward D., Yousef Tizabi, Amir H. Rezvani, D Patrick Caldwell, Ann Petro, and Bruk Getachew. “Chronic nicotine and dizocilpine effects on regionally specific nicotinic and NMDA glutamate receptor binding.” Brain Res 1041, no. 2 (April 18, 2005): 132–42. https://doi.org/10.1016/j.brainres.2005.01.104.Full Text Link to Item
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Levin, Edward D. “Extracellular superoxide dismutase (EC-SOD) quenches free radicals and attenuates age-related cognitive decline: opportunities for novel drug development in aging.” Curr Alzheimer Res 2, no. 2 (April 2005): 191–96. https://doi.org/10.2174/1567205053585710.Full Text Link to Item
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Levin, Edward D., Holly A. Swain, Sue Donerly, and Elwood Linney. “Developmental chlorpyrifos effects on hatchling zebrafish swimming behavior.” Neurotoxicol Teratol 26, no. 6 (November 2004): 719–23. https://doi.org/10.1016/j.ntt.2004.06.013.Full Text Link to Item
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Levin, Edward D., and Elaine Chen. “Nicotinic involvement in memory function in zebrafish.” Neurotoxicol Teratol 26, no. 6 (November 2004): 731–35. https://doi.org/10.1016/j.ntt.2004.06.010.Full Text Link to Item
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Scalzo, Frank M., and Edward D. Levin. “The use of zebrafish (Danio rerio) as a model system in neurobehavioral toxicology.” Neurotoxicol Teratol 26, no. 6 (November 2004): 707–8. https://doi.org/10.1016/j.ntt.2004.06.008.Full Text Link to Item
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Levin, Edward D., Elyssa Weber, and Laura Icenogle. “Baclofen interactions with nicotine in rats: effects on memory.” Pharmacol Biochem Behav 79, no. 2 (October 2004): 343–48. https://doi.org/10.1016/j.pbb.2004.08.013.Full Text Link to Item
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Rezvani, Amir H., and Edward D. Levin. “Adolescent and adult rats respond differently to nicotine and alcohol: motor activity and body temperature.” Int J Dev Neurosci 22, no. 5–6 (August 2004): 349–54. https://doi.org/10.1016/j.ijdevneu.2004.03.007.Full Text Link to Item
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Rezvani, A. H., and E. D. Levin. “Erratum: Nicotine-antipsychotic drug interactions and attentional performance in female rats (European Journal of Pharmacology (2004) 486 (175-182) DOI: 10.1016/j.ejphar.2003.12.021.).” European Journal of Pharmacology 489, no. 3 (April 12, 2004): 215. https://doi.org/10.1016/j.ejphar.2004.03.009.Full Text
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Rezvani, Amir H., and Edward D. Levin. “Nicotine-antipsychotic drug interactions and attentional performance in female rats.” Eur J Pharmacol 486, no. 2 (February 20, 2004): 175–82. https://doi.org/10.1016/j.ejphar.2003.12.021.Full Text Link to Item
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White, Heidi K., and Edward D. Levin. “Chronic transdermal nicotine patch treatment effects on cognitive performance in age-associated memory impairment.” Psychopharmacology (Berl) 171, no. 4 (February 2004): 465–71. https://doi.org/10.1007/s00213-003-1614-8.Full Text Link to Item
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Icenogle, Laura M., N Channelle Christopher, W Paul Blackwelder, D Patrick Caldwell, Dan Qiao, Frederic J. Seidler, Theodore A. Slotkin, and Edward D. Levin. “Behavioral alterations in adolescent and adult rats caused by a brief subtoxic exposure to chlorpyrifos during neurulation.” Neurotoxicol Teratol 26, no. 1 (January 2004): 95–101. https://doi.org/10.1016/j.ntt.2003.09.001.Full Text Link to Item
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Levin, Edward D., Susan Brunssen, Gary W. Wolfe, and G Jean Harry. “Neurobehavioral assessment of mice after developmental AZT exposure.” Neurotoxicol Teratol 26, no. 1 (January 2004): 65–71. https://doi.org/10.1016/j.ntt.2003.10.001.Full Text Link to Item
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Aldridge, Justin E., Jennifer A. Gibbons, Meghan M. Flaherty, Marisa L. Kreider, Jocelyn A. Romano, and Edward D. Levin. “Heterogeneity of toxicant response: sources of human variability.” Toxicol Sci 76, no. 1 (November 2003): 3–20. https://doi.org/10.1093/toxsci/kfg204.Full Text Link to Item
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Levin, Edward D., Damyon Sledge, Avanti Baruah, and Nii A. Addy. “Ventral hippocampal NMDA blockade and nicotinic effects on memory function.” Brain Res Bull 61, no. 5 (September 30, 2003): 489–95. https://doi.org/10.1016/s0361-9230(03)00183-7.Full Text Link to Item
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Levin, Edward D., Amir H. Rezvani, Daniel Montoya, Jed E. Rose, and H Scott Swartzwelder. “Adolescent-onset nicotine self-administration modeled in female rats.” Psychopharmacology (Berl) 169, no. 2 (September 2003): 141–49. https://doi.org/10.1007/s00213-003-1486-y.Full Text Link to Item
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Levin, Edward D., and Channelle N. Christopher. “Lobeline-induced learning improvement of rats in the radial-arm maze.” Pharmacol Biochem Behav 76, no. 1 (August 2003): 133–39. https://doi.org/10.1016/s0091-3057(03)00216-8.Full Text Link to Item
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Rezvani, Amir H., and Edward D. Levin. “Nicotine-alcohol interactions and attentional performance on an operant visual signal detection task in female rats.” Pharmacol Biochem Behav 76, no. 1 (August 2003): 75–83. https://doi.org/10.1016/s0091-3057(03)00193-x.Full Text Link to Item
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Levin, Edward D., W Paul Blackwelder, Howard B. Glasgow, JoAnn M. Burkholder, Peter D. R. Moeller, and John S. Ramsdell. “Learning impairment caused by a toxin produced by Pfiesteria piscicida infused into the hippocampus of rats.” Neurotoxicol Teratol 25, no. 4 (July 2003): 419–26. https://doi.org/10.1016/s0892-0362(03)00011-4.Full Text Link to Item
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May-Simera, Helen, and Edward D. Levin. “NMDA systems in the amygdala and piriform cortex and nicotinic effects on memory function.” Brain Res Cogn Brain Res 17, no. 2 (July 2003): 475–83. https://doi.org/10.1016/s0926-6410(03)00163-0.Full Text Link to Item
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Rezvani, Amir H., and Edward D. Levin. “Nicotinic-glutamatergic interactions and attentional performance on an operant visual signal detection task in female rats.” Eur J Pharmacol 465, no. 1–2 (March 28, 2003): 83–90. https://doi.org/10.1016/s0014-2999(03)01439-0.Full Text Link to Item
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Addy, Nii A., Aya Nakijama, and Edward D. Levin. “Nicotinic mechanisms of memory: effects of acute local DHbetaE and MLA infusions in the basolateral amygdala.” Brain Res Cogn Brain Res 16, no. 1 (March 2003): 51–57. https://doi.org/10.1016/s0926-6410(02)00209-4.Full Text Link to Item
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Yang, Yen Kuang, Joseph P. McEvoy, William H. Wilson, Edward D. Levin, and Jed E. Rose. “Reliabilities and intercorrelations of reported and objective measures of smoking in patients with schizophrenia.” Schizophr Res 60, no. 1 (March 1, 2003): 9–12. https://doi.org/10.1016/s0920-9964(02)00208-6.Full Text Link to Item
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Levin, E. D. “Behavioral Toxicology Society 2002 annual meeting report.” Neurotoxicology and Teratology 25, no. 1 (January 1, 2003): 77–80. https://doi.org/10.1016/S0892-0362(02)00355-0.Full Text
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Levin, E. D., E. Chrysanthis, K. Yacisin, and E. Linney. “Erratum: Chlorpyrifos exposure of developing zebrafish: Effects on survival and long-term effects on response latency and spatial discrimination (Neurotoxicology and Teratology (2003) 25 (51-57)).” Neurotoxicology and Teratology 25, no. 5 (January 1, 2003): 639. https://doi.org/10.1016/S0892-0362(03)00077-1.Full Text
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Levin, Edward D., Elizabeth Chrysanthis, Kari Yacisin, and Elwood Linney. “Chlorpyrifos exposure of developing zebrafish: effects on survival and long-term effects on response latency and spatial discrimination.” Neurotoxicol Teratol 25, no. 1 (January 2003): 51–57. https://doi.org/10.1016/s0892-0362(02)00322-7.Full Text Link to Item
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Levin, Edward D. “Nicotinic receptor subtypes and cognitive function.” J Neurobiol 53, no. 4 (December 2002): 633–40. https://doi.org/10.1002/neu.10151.Full Text Link to Item
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Rezvani, Amir H., Philip J. Bushnell, and Edward D. Levin. “Effects of nicotine and mecamylamine on choice accuracy in an operant visual signal detection task in female rats.” Psychopharmacology (Berl) 164, no. 4 (December 2002): 369–75. https://doi.org/10.1007/s00213-002-1221-0.Full Text Link to Item
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Levin, Edward D., Nii Addy, Avanti Baruah, Alana Elias, N Channelle Christopher, Frederic J. Seidler, and Theodore A. Slotkin. “Prenatal chlorpyrifos exposure in rats causes persistent behavioral alterations.” Neurotoxicol Teratol 24, no. 6 (November 2002): 733–41. https://doi.org/10.1016/s0892-0362(02)00272-6.Full Text Link to Item
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Addy, Nii, and Edward D. Levin. “Nicotine interactions with haloperidol, clozapine and risperidone and working memory function in rats.” Neuropsychopharmacology 27, no. 4 (October 2002): 534–41. https://doi.org/10.1016/S0893-133X(02)00327-5.Full Text Link to Item
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Levin, E. D., and A. H. Rezvani. “Nicotinic treatment for cognitive dysfunction.” Curr Drug Targets Cns Neurol Disord 1, no. 4 (August 2002): 423–31. https://doi.org/10.2174/1568007023339102.Full Text Link to Item
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Rezvani, Amir H., and Edward D. Levin. “Nicotine-alcohol interactions and cognitive function in rats.” Pharmacol Biochem Behav 72, no. 4 (July 2002): 865–72. https://doi.org/10.1016/s0091-3057(02)00762-1.Full Text Link to Item
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Qiao, D., F. J. Seidler, E. D. Levin, S. Padilla, and T. A. Slotkin. “Developmental neurotoxicity of chlorpyrifos: Defining the vulnerable period.” Faseb Journal 16, no. 5 (March 22, 2002): A949–A949.Link to Item
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Arthur, David, and Edward D. Levin. “Chronic inhibition of alpha4beta2 nicotinic receptors in the ventral hippocampus of rats: impacts on memory and nicotine response.” Psychopharmacology (Berl) 160, no. 2 (March 2002): 140–45. https://doi.org/10.1007/s00213-001-0961-6.Full Text Link to Item
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Levin, Edward D., N Channelle Christopher, Sohail Lateef, Belal M. Elamir, Manisha Patel, Li-Ping Liang, and James D. Crapo. “Extracellular superoxide dismutase overexpression protects against aging-induced cognitive impairment in mice.” Behav Genet 32, no. 2 (March 2002): 119–25. https://doi.org/10.1023/a:1015201823417.Full Text Link to Item
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Rossler, I. B., R. C. Johnson, A. D. Krystal, R. D. Weiner, E. D. Levin, P. Logue, C. E. Coffey, and C. L. Edwards. “A naturalistic study of the effects of smoking on the cognitive side effects of ECT.” Journal of Ect 18, no. 1 (March 1, 2002): 64–64.Link to Item
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Esposito, E., R. Cortesi, R. Porta, F. Trento, and C. Nastruzzi. “Effect of long-term stabilization of cationic liposomes as defibrotide delivery system for antithrombotic activity.” Drug Development Research 55, no. 2 (January 1, 2002): 127–38. https://doi.org/10.1002/ddr.10041.Full Text
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Levin, E. D., A. Bradley, N. Addy, and N. Sigurani. “Hippocampal alpha 7 and alpha 4 beta 2 nicotinic receptors and working memory.” Neuroscience 109, no. 4 (2002): 757–65. https://doi.org/10.1016/s0306-4522(01)00538-3.Full Text Link to Item
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Levin, E. D., and N. C. Christopher. “Persistence of nicotinic agonist RJR 2403-induced working memory improvement in rats.” Drug Development Research 55, no. 2 (January 1, 2002): 97–103. https://doi.org/10.1002/ddr.10024.Full Text
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Bettany, J. H., and E. D. Levin. “Ventral hippocampal alpha 7 nicotinic receptor blockade and chronic nicotine effects on memory performance in the radial-arm maze.” Pharmacol Biochem Behav 70, no. 4 (December 2001): 467–74. https://doi.org/10.1016/s0091-3057(01)00643-8.Full Text Link to Item
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Rezvani, A. H., P. J. Bushnell, J. M. Burkholder, H. B. Glasgow, and E. D. Levin. “Specificity of cognitive impairment from Pfiesteria piscicida exposure in rats: attention and visual function versus behavioral plasticity.” Neurotoxicol Teratol 23, no. 6 (November 2001): 609–16. https://doi.org/10.1016/s0892-0362(01)00169-6.Full Text Link to Item
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Levin, E. D. “A rat model of the cognitive impairment from Pfiesteria piscicida exposure.” Environ Health Perspect 109 Suppl 5 (October 2001): 757–63. https://doi.org/10.1289/ehp.01109s5757.Full Text Link to Item
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Levin, E. D., N. Addy, A. Nakajima, N. C. Christopher, F. J. Seidler, and T. A. Slotkin. “Persistent behavioral consequences of neonatal chlorpyrifos exposure in rats.” Brain Res Dev Brain Res 130, no. 1 (September 23, 2001): 83–89. https://doi.org/10.1016/s0165-3806(01)00215-2.Full Text Link to Item
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Levin, E. D., C. K. Conners, D. Silva, W. Canu, and J. March. “Effects of chronic nicotine and methylphenidate in adults with attention deficit/hyperactivity disorder.” Exp Clin Psychopharmacol 9, no. 1 (February 2001): 83–90. https://doi.org/10.1037/1064-1297.9.1.83.Full Text Link to Item
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Rezvani, A. H., and E. D. Levin. “Cognitive effects of nicotine.” Biol Psychiatry 49, no. 3 (February 1, 2001): 258–67. https://doi.org/10.1016/s0006-3223(00)01094-5.Full Text Link to Item
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Arthur, D., and E. D. Levin. “Spatial and non-spatial discrimination learning in zebrafish (Danio rerio).” Animal Cognition 4 (2001): 125–31.
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Levin, E. D., T. Mead, A. H. Rezvani, J. E. Rose, C. Gallivan, and R. Gross. “The nicotinic antagonist mecamylamine preferentially inhibits cocaine vs. food self-administration in rats.” Physiol Behav 71, no. 5 (December 2000): 565–70. https://doi.org/10.1016/s0031-9384(00)00382-6.Full Text Link to Item
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Bancroft, A., and E. D. Levin. “Ventral hippocampal alpha4beta2 nicotinic receptors and chronic nicotine effects on memory.” Neuropharmacology 39, no. 13 (October 2000): 2770–78. https://doi.org/10.1016/s0028-3908(00)00099-x.Full Text Link to Item
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Narahashi, T., C. P. Fenster, M. W. Quick, R. A. Lester, W. Marszalec, G. L. Aistrup, D. B. Sattelle, B. R. Martin, and E. D. Levin. “Symposium overview: mechanism of action of nicotine on neuronal acetylcholine receptors, from molecule to behavior.” Toxicol Sci 57, no. 2 (October 2000): 193–202. https://doi.org/10.1093/toxsci/57.2.193.Full Text Link to Item
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Rusted, J. M., P. A. Newhouse, and E. D. Levin. “Nicotinic treatment for degenerative neuropsychiatric disorders such as Alzheimer's disease and Parkinson's disease.” Behav Brain Res 113, no. 1–2 (August 2000): 121–29. https://doi.org/10.1016/s0166-4328(00)00207-2.Full Text Link to Item
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White, A. M., A. J. Ghia, E. D. Levin, and H. S. Swartzwelder. “Binge pattern ethanol exposure in adolescent and adult rats: differential impact on subsequent responsiveness to ethanol.” Alcohol Clin Exp Res 24, no. 8 (August 2000): 1251–56.Link to Item
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Bushnell, P. J., E. D. Levin, R. T. Marrocco, M. F. Sarter, B. J. Strupp, and D. M. Warburton. “Attention as a target of intoxication: insights and methods from studies of drug abuse.” Neurotoxicol Teratol 22, no. 4 (July 2000): 487–502. https://doi.org/10.1016/s0892-0362(00)00077-5.Full Text Link to Item
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Levin, E. D., A. H. Rezvani, N. C. Christopher, H. B. Glasgow, N. J. Deamer-Melia, J. M. Burkholder, V. C. Moser, and K. Jensen. “Rapid neurobehavioral analysis of Pfiesteria piscicida effects in juvenile and adult rats.” Neurotoxicol Teratol 22, no. 4 (July 2000): 533–40. https://doi.org/10.1016/s0892-0362(00)00080-5.Full Text Link to Item
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Grilly, D. M., B. B. Simon, and E. D. Levin. “Nicotine enhances stimulus detection performance of middle- and old-aged rats: a longitudinal study.” Pharmacol Biochem Behav 65, no. 4 (April 2000): 665–70. https://doi.org/10.1016/s0091-3057(99)00259-2.Full Text Link to Item
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Levin, E. D., and A. H. Rezvani. “Development of nicotinic drug therapy for cognitive disorders.” Eur J Pharmacol 393, no. 1–3 (March 30, 2000): 141–46. https://doi.org/10.1016/s0014-2999(99)00885-7.Full Text Link to Item
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Levin, E. D., F. H. Brucato, and J. D. Crapo. “Molecular overexpression of extracellular superoxide dismutase increases the dependency of learning and memory performance on motivational state.” Behav Genet 30, no. 2 (March 2000): 95–100. https://doi.org/10.1023/a:1001947003299.Full Text Link to Item
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Keller, J. M., J. N. Meyer, M. Mattie, T. Augspurger, M. Rau, J. Dong, and E. D. Levin. “Assessment of immunotoxicology in wild populations: Review and recommendations.” Reviews in Toxicology 3, no. 1–4 (December 1, 1999): 167–212.
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Levin, E. D., C. Bettegowda, J. Blosser, and J. Gordon. “AR-R17779, and alpha7 nicotinic agonist, improves learning and memory in rats.” Behav Pharmacol 10, no. 6–7 (November 1999): 675–80. https://doi.org/10.1097/00008877-199911000-00014.Full Text Link to Item
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Levin, E. D., and P. Lippiello. “Mutually potentiating effects of mecamylamine and haloperidol in producing catalepsy in rats.” Drug Development Research 47, no. 2 (August 4, 1999): 90–96. https://doi.org/10.1002/(SICI)1098-2299(199906)47:2<90::AID-DDR4>3.0.CO;2-5.Full Text
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Levin, E. D., M. Imad Damaj, W. Glassco, E. L. May, and B. R. Martin. “Bridged nicotine, isonicotine, and norisonicotine effects on working memory performance of rats in the radial-arm maze.” Drug Development Research 46, no. 2 (May 12, 1999): 107–11. https://doi.org/10.1002/(SICI)1098-2299(199902)46:2<107::AID-DDR3>3.0.CO;2-C.Full Text
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Levin, E. D., B. B. Simon, D. E. Schmechel, H. B. Glasgow, N. J. Deamer-Melia, J. M. Burkholder, V. C. Moser, K. Jensen, and G. J. Harry. “Pfiesteria toxin and learning performance.” Neurotoxicol Teratol 21, no. 3 (May 1999): 215–21. https://doi.org/10.1016/s0892-0362(98)00041-5.Full Text Link to Item
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Gingras, J. L., N. E. Leatherman, A. R. Cutler, and E. D. Levin. “Nicotine and/or cocaine alters postnatal ventilatory control in the rat pup gestationally exposed.” Pediatric Research 45, no. 4 (April 1, 1999): 51A-51A.Link to Item
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White, H. K., and E. D. Levin. “Four-week nicotine skin patch treatment effects on cognitive performance in Alzheimer's disease.” Psychopharmacology (Berl) 143, no. 2 (April 1999): 158–65. https://doi.org/10.1007/s002130050931.Full Text Link to Item
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Wilkerson, A., and E. D. Levin. “Ventral hippocampal dopamine D1 and D2 systems and spatial working memory in rats.” Neuroscience 89, no. 3 (March 1999): 743–49. https://doi.org/10.1016/s0306-4522(98)00346-7.Full Text Link to Item
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Gainetdinov, R. R., W. C. Wetsel, S. R. Jones, E. D. Levin, M. Jaber, and M. G. Caron. “Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity.” Science 283, no. 5400 (January 15, 1999): 397–401. https://doi.org/10.1126/science.283.5400.397.Full Text Link to Item
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Levin, E. D., N. C. Christopher, T. Weaver, J. Moore, and F. Brucato. “Ventral hippocampal ibotenic acid lesions block chronic nicotine-induced spatial working memory improvement in rats.” Brain Res Cogn Brain Res 7, no. 3 (January 1999): 405–10. https://doi.org/10.1016/s0926-6410(98)00044-5.Full Text Link to Item
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Levin, E. D., C. Bettegowda, T. Weaver, and N. C. Christopher. “Nicotine-dizocilpine interactions and working and reference memory performance of rats in the radial-arm maze.” Pharmacol Biochem Behav 61, no. 3 (November 1998): 335–40. https://doi.org/10.1016/s0091-3057(98)00109-9.Full Text Link to Item
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Levin, E. D., C. K. Conners, D. Silva, S. C. Hinton, W. H. Meck, J. March, and J. E. Rose. “Transdermal nicotine effects on attention.” Psychopharmacology (Berl) 140, no. 2 (November 1998): 135–41. https://doi.org/10.1007/s002130050750.Full Text Link to Item
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Levin, E. D., T. C. Brady, E. C. Hochrein, T. D. Oury, L. M. Jonsson, S. L. Marklund, and J. D. Crapo. “Molecular manipulations of extracellular superoxide dismutase: functional importance for learning.” Behav Genet 28, no. 5 (September 1998): 381–90. https://doi.org/10.1023/a:1021673703129.Full Text Link to Item
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Levin, E. D., and B. B. Simon. “Nicotinic acetylcholine involvement in cognitive function in animals.” Psychopharmacology (Berl) 138, no. 3–4 (August 1998): 217–30. https://doi.org/10.1007/s002130050667.Full Text Link to Item
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Kelly, K. A., C. M. Havrilla, T. C. Brady, K. H. Abramo, and E. D. Levin. “Oxidative stress in toxicology: established mammalian and emerging piscine model systems.” Environ Health Perspect 106, no. 7 (July 1998): 375–84. https://doi.org/10.1289/ehp.98106375.Full Text Link to Item
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Schwartz-Bloom, R. D., K. J. McDonough, P. J. Chase, L. E. Chadwick, J. R. Inglefield, and E. D. Levin. “Long-term neuroprotection by benzodiazepine full versus partial agonists after transient cerebral ischemia in the gerbil [corrected].” J Cereb Blood Flow Metab 18, no. 5 (May 1998): 548–58. https://doi.org/10.1097/00004647-199805000-00010.Full Text Link to Item
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Markwiese, B. J., S. K. Acheson, E. D. Levin, W. A. Wilson, and H. S. Swartzwelder. “Differential effects of ethanol on memory in adolescent and adult rats.” Alcohol Clin Exp Res 22, no. 2 (April 1998): 416–21.Link to Item
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Felix, R., and E. D. Levin. “Nicotinic antagonist administration into the ventral hippocampus and spatial working memory in rats.” Neuroscience 81, no. 4 (December 1997): 1009–17. https://doi.org/10.1016/s0306-4522(97)00224-8.Full Text Link to Item
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Levin, E. D. “Chronic haloperidol administration does not block acute nicotine-induced improvements in radial-arm maze performance in the rat.” Pharmacol Biochem Behav 58, no. 4 (December 1997): 899–902. https://doi.org/10.1016/s0091-3057(97)00052-x.Full Text Link to Item
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Levin, E. D., D. E. Schmechel, J. B. Burkholder, N. J. Deamer-Melia, V. C. Moser, and G. J. Harry. “Persisting learning deficits in rats after exposure to Pfiesteria piscicida.” Environ Health Perspect 105, no. 12 (December 1997): 1320–25. https://doi.org/10.1289/ehp.971051320.Full Text Link to Item
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Newhouse, P. A., A. Potter, and E. D. Levin. “Nicotinic system involvement in Alzheimer's and Parkinson's diseases. Implications for therapeutics.” Drugs Aging 11, no. 3 (September 1997): 206–28. https://doi.org/10.2165/00002512-199711030-00005.Full Text Link to Item
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Piantadosi, C. A., J. Zhang, E. D. Levin, R. J. Folz, and D. E. Schmechel. “Apoptosis and delayed neuronal damage after carbon monoxide poisoning in the rat.” Exp Neurol 147, no. 1 (September 1997): 103–14. https://doi.org/10.1006/exnr.1997.6584.Full Text Link to Item
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Levin, E. D., N. C. Christopher, and S. J. Briggs. “Chronic nicotinic agonist and antagonist effects on T-maze alternation.” Physiol Behav 61, no. 6 (June 1997): 863–66. https://doi.org/10.1016/s0031-9384(96)00609-9.Full Text Link to Item
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Levin, E. D., S. Kaplan, and A. Boardman. “Acute nicotine interactions with nicotinic and muscarinic antagonists: working and reference memory effects in the 16-arm radial maze.” Behav Pharmacol 8, no. 2–3 (June 1997): 236–42.Link to Item
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Levin, E. D., D. Torry, N. C. Christopher, X. Yu, G. Einstein, and R. D. Schwartz-Bloom. “Is binding to nicotinic acetylcholine and dopamine receptors related to working memory in rats?” Brain Res Bull 43, no. 3 (1997): 295–304. https://doi.org/10.1016/s0361-9230(97)00009-9.Full Text Link to Item
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Levin, E. D., A. Wilkerson, J. P. Jones, N. C. Christopher, and S. J. Briggs. “Prenatal nicotine effects on memory in rats: pharmacological and behavioral challenges.” Brain Res Dev Brain Res 97, no. 2 (December 23, 1996): 207–15. https://doi.org/10.1016/s0165-3806(96)00144-7.Full Text Link to Item
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Chambers, R. A., J. Moore, J. P. McEvoy, and E. D. Levin. “Cognitive effects of neonatal hippocampal lesions in a rat model of schizophrenia.” Neuropsychopharmacology 15, no. 6 (December 1996): 587–94. https://doi.org/10.1016/S0893-133X(96)00132-7.Full Text Link to Item
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Levin, E. D. “Nicotinic agonist and antagonist effects on memory.” Drug Development Research 38, no. 3–4 (December 1, 1996): 188–95. https://doi.org/10.1002/(SICI)1098-2299(199607/08)38:3/4<188::AID-DDR7>3.0.CO;2-I.Full Text
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Levin, E. D., J. E. Rose, P. Lippelio, and J. Robinson. “Nicotine and neurobehavioral function.” Drug Development Research 38, no. 3–4 (December 1, 1996): 135. https://doi.org/10.1002/(SICI)1098-2299(199607/08)38:3/4<135::AID-DDR1>3.0.CO;2-N.Full Text
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Levin, E. D., K. Toll, G. Chang, N. C. Christopher, S. J. Briggs, and W. Fiedler. “Epibatidine, a potent nicotinic agonist: Effects on learning and memory in the radial-arm maze.” Medicinal Chemistry Research 6, no. 7–8 (December 1, 1996): 543–54.
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Levin, E. D., N. C. Christopher, S. J. Briggs, and J. Todd Auman. “Chronic nicotine-induced improvement of spatial working memory and D2 dopamine effects in rats.” Drug Development Research 39, no. 1 (December 1, 1996): 29–35. https://doi.org/10.1002/(SICI)1098-2299(19960901)39:1<29::AID-DDR4>3.0.CO;2-M.Full Text
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Cutler, A. R., A. E. Wilkerson, J. L. Gingras, and E. D. Levin. “Prenatal cocaine and/or nicotine exposure in rats: preliminary findings on long-term cognitive outcome and genital development at birth.” Neurotoxicol Teratol 18, no. 6 (November 1996): 635–43. https://doi.org/10.1016/s0892-0362(96)00125-0.Full Text Link to Item
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Levin, E. D., W. Wilson, J. E. Rose, and J. McEvoy. “Nicotine-haloperidol interactions and cognitive performance in schizophrenics.” Neuropsychopharmacology 15, no. 5 (November 1996): 429–36. https://doi.org/10.1016/S0893-133X(96)00018-8.Full Text Link to Item
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Brucato, F. H., E. D. Levin, D. D. Mott, D. V. Lewis, W. A. Wilson, and H. S. Swartzwelder. “Hippocampal long-term potentiation and spatial learning in the rat: effects of GABAB receptor blockade.” Neuroscience 74, no. 2 (September 1996): 331–39. https://doi.org/10.1016/0306-4522(96)00131-5.Full Text Link to Item
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Levin, E. D., P. Kim, and R. Meray. “Chronic nicotine working and reference memory effects in the 16-arm radial maze: interactions with D1 agonist and antagonist drugs.” Psychopharmacology (Berl) 127, no. 1 (September 1996): 25–30. https://doi.org/10.1007/BF02805971.Full Text Link to Item
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Kim, J. S., and E. D. Levin. “Nicotinic, muscarinic and dopaminergic actions in the ventral hippocampus and the nucleus accumbens: effects on spatial working memory in rats.” Brain Res 725, no. 2 (July 1, 1996): 231–40. https://doi.org/10.1016/0006-8993(96)00213-2.Full Text Link to Item
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Levin, E. D., C. K. Conners, E. Sparrow, S. C. Hinton, D. Erhardt, W. H. Meck, J. E. Rose, and J. March. “Nicotine effects on adults with attention-deficit/hyperactivity disorder.” Psychopharmacology (Berl) 123, no. 1 (January 1996): 55–63. https://doi.org/10.1007/BF02246281.Full Text Link to Item
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Conners, C. K., E. D. Levin, E. Sparrow, S. C. Hinton, D. Erhardt, W. H. Meck, J. E. Rose, and J. March. “Nicotine and attention in adult attention deficit hyperactivity disorder (ADHD).” Psychopharmacol Bull 32, no. 1 (1996): 67–73.Link to Item
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Levin, E. D., and D. Torry. “Acute and chronic nicotine effects on working memory in aged rats.” Psychopharmacology (Berl) 123, no. 1 (January 1996): 88–97. https://doi.org/10.1007/BF02246285.Full Text Link to Item
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Levin, E. D. “Pergolide interactions with nicotine and pilocarpine in rats on the radial-arm maze.” Pharmacol Biochem Behav 52, no. 4 (December 1995): 837–40. https://doi.org/10.1016/0091-3057(95)00165-s.Full Text Link to Item
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Beckham, J. C., A. A. Roodman, R. H. Shipley, M. A. Hertzberg, G. H. Cunha, H. S. Kudler, E. D. Levin, J. E. Rose, and J. A. Fairbank. “Smoking in Vietnam combat veterans with post-traumatic stress disorder.” J Trauma Stress 8, no. 3 (July 1995): 461–72. https://doi.org/10.1007/BF02102970.Full Text Link to Item
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Levin, E. D., J. E. Rose, and L. Abood. “Effects of nicotinic dimethylaminoethyl esters on working memory performance of rats in the radial-arm maze.” Pharmacol Biochem Behav 51, no. 2–3 (June 1995): 369–73. https://doi.org/10.1016/0091-3057(94)00406-9.Full Text Link to Item
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Levin, E. D., and J. E. Rose. “Acute and chronic nicotinic interactions with dopamine systems and working memory performance.” Ann N Y Acad Sci 757 (May 10, 1995): 245–52. https://doi.org/10.1111/j.1749-6632.1995.tb17481.x.Full Text Link to Item
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Rose, J. E., E. D. Levin, F. M. Behm, E. C. Westman, R. M. Stein, J. D. Lane, and G. V. Ripka. “Combined administration of agonist-antagonist as a method of regulating receptor activation.” Ann N Y Acad Sci 757 (May 10, 1995): 218–21. https://doi.org/10.1111/j.1749-6632.1995.tb17478.x.Full Text Link to Item
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McEvoy, J. P., O. Freudenreich, E. D. Levin, and J. E. Rose. “Haloperidol increases smoking in patients with schizophrenia.” Psychopharmacology (Berl) 119, no. 1 (May 1995): 124–26. https://doi.org/10.1007/BF02246063.Full Text Link to Item
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McEvoy, J., O. Freudenreich, M. McGee, C. VanderZwaag, E. Levin, and J. Rose. “Clozapine decreases smoking in patients with chronic schizophrenia.” Biol Psychiatry 37, no. 8 (April 15, 1995): 550–52. https://doi.org/10.1016/0006-3223(94)00365-A.Full Text Link to Item
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CUTLER, A. R., A. E. WILKERSON, J. L. GINGRAS, and E. D. LEVIN. “PRENATAL COCAINE AND NICOTINE EXPOSURE IN RATS - EFFECTS ON LONG-TERM COGNITIVE OUTCOME AND SEXUAL-DIFFERENTIATION.” Pediatric Research 37, no. 4 (April 1, 1995): A14–A14.Link to Item
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Levin, E. D., N. C. Christopher, and M. B. Abou-Donia. “Triphenyl phosphite-induced impairment of spatial alternation learning.” J Toxicol Environ Health 44, no. 4 (April 1995): 461–67. https://doi.org/10.1080/15287399509531974.Full Text Link to Item
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Levin, Edward D. “Reply.” Journal of Clinical Psychopharmacology 15, no. 2 (April 1995): 146–146. https://doi.org/10.1097/00004714-199504000-00017.Full Text
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Sudan, B. J. “Nicotine skin patch treatment and adverse reactions: skin irritation, skin sensitization, and nicotine as a hapten.” J Clin Psychopharmacol 15, no. 2 (April 1995): 145–46. https://doi.org/10.1097/00004714-199504000-00016.Full Text Link to Item
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Bushnell, P. J., E. D. Levin, and D. H. Overstreet. “Spatial working and reference memory in rats bred for autonomic sensitivity to cholinergic stimulation: acquisition, accuracy, speed, and effects of cholinergic drugs.” Neurobiol Learn Mem 63, no. 2 (March 1995): 116–32. https://doi.org/10.1006/nlme.1995.1012.Full Text Link to Item
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Andrén, P. E., E. D. Levin, U. Liminga, and L. Gunne. “Behavioral and neurochemical consequences of ibotenic acid lesion in the subthalamic nucleus of the common marmoset.” Brain Res Bull 36, no. 3 (1995): 301–7. https://doi.org/10.1016/0361-9230(94)00206-g.Full Text Link to Item
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Westman, E. C., E. D. Levin, and J. E. Rose. “Nicotine as a therapeutic drug.” N C Med J 56, no. 1 (January 1995): 48–51.Link to Item
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Rose, J. E., E. D. Levin, F. M. Behm, E. C. Westman, R. M. Stein, J. D. Lane, and G. V. Ripka. “Combined Agonist-Antagonist Treatment for Nicotine and Other Drug Dependencies.” Neuropsychopharmacology 11, no. 4 (December 1994): 281. https://doi.org/10.1038/sj.npp.1380199.Full Text Link to Item
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Kotlova, E. K., E. D. Levin, M. P. Iusupova, B. V. Rozynov, and V. M. Stepanov. “[A transformylation reaction--transfer of an N-formyl residue to amino acids and peptides in nucleophilic groups--as a side reaction of peptide synthesis].” Bioorg Khim 20, no. 11 (November 1994): 1186–95.Link to Item
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Levin, E. D., S. J. Briggs, N. C. Christopher, and J. T. Auman. “Working memory performance and cholinergic effects in the ventral tegmental area and substantia nigra.” Brain Res 657, no. 1–2 (September 19, 1994): 165–70. https://doi.org/10.1016/0006-8993(94)90964-4.Full Text Link to Item
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Rose, J. E., F. M. Behm, E. C. Westman, E. D. Levin, R. M. Stein, and G. V. Ripka. “Mecamylamine combined with nicotine skin patch facilitates smoking cessation beyond nicotine patch treatment alone.” Clin Pharmacol Ther 56, no. 1 (July 1994): 86–99. https://doi.org/10.1038/clpt.1994.105.Full Text Link to Item
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Levin, E. D., E. C. Westman, R. M. Stein, E. Carnahan, M. Sanchez, S. Herman, F. M. Behm, and J. E. Rose. “Nicotine skin patch treatment increases abstinence, decreases withdrawal symptoms, and attenuates rewarding effects of smoking.” J Clin Psychopharmacol 14, no. 1 (February 1994): 41–49.Link to Item
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Brucato, F. H., E. D. Levin, J. E. Rose, and H. S. Swartzwelder. “Intracerebroventricular nicotine and mecamylamine alter radial‐arm maze performance in rats.” Drug Development Research 31, no. 1 (January 1, 1994): 18–23. https://doi.org/10.1002/ddr.430310104.Full Text
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Levin, E. D., and B. Eisner. “Nicotine interactions with dopamine agonists: Effects on working memory function.” Drug Development Research 31, no. 1 (January 1, 1994): 32–37. https://doi.org/10.1002/ddr.430310106.Full Text
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Levin, E. D., and J. A. Rosecrans. “Promise of nicotinic‐based therapeutic treatments.” Drug Development Research 31, no. 1 (January 1, 1994): 1–2. https://doi.org/10.1002/ddr.430310102.Full Text
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MCEVOY, J. P., J. E. ROSE, E. D. LEVIN, C. VANDERZWAAG, and M. MCGEE. “CLOZAPINE DECREASES DRIVE TO SMOKE.” Schizophrenia Research 11, no. 2 (January 1, 1994): 104–104.Link to Item
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Rose, J. E., F. M. Behm, E. C. Westman, E. D. Levin, R. M. Stein, J. D. Lane, and G. V. Ripka. “Combined Effects of Nicotine and Mecamylamine in Attenuating Smoking Satisfaction.” Experimental and Clinical Psychopharmacology 2, no. 4 (January 1, 1994): 328–44. https://doi.org/10.1037/1064-1297.2.4.328.Full Text
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Levin, E. D., F. Behm, E. Carnahan, R. LeClair, R. Shipley, and J. E. Rose. “Clinical trials using ascorbic acid aerosol to aid smoking cessation.” Drug Alcohol Depend 33, no. 3 (October 1993): 211–23. https://doi.org/10.1016/0376-8716(93)90108-3.Full Text Link to Item
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Levin, E. D., N. C. Christopher, S. J. Briggs, and J. E. Rose. “Chronic nicotine reverses working memory deficits caused by lesions of the fimbria or medial basalocortical projection.” Brain Res Cogn Brain Res 1, no. 3 (October 1993): 137–43. https://doi.org/10.1016/0926-6410(93)90021-v.Full Text Link to Item
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Rose, J. E., E. D. Levin, and N. Benowitz. “Saliva nicotine as an index of plasma levels in nicotine skin patch users.” Ther Drug Monit 15, no. 5 (October 1993): 431–35. https://doi.org/10.1097/00007691-199310000-00012.Full Text Link to Item
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Westman, E. C., E. D. Levin, and J. E. Rose. “The nicotine patch in smoking cessation. A randomized trial with telephone counseling.” Arch Intern Med 153, no. 16 (August 23, 1993): 1917–23.Link to Item
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Bushnell, P. J., and E. D. Levin. “Effects of dopaminergic drugs on working and reference memory in rats.” Pharmacol Biochem Behav 45, no. 4 (August 1993): 765–76. https://doi.org/10.1016/0091-3057(93)90119-e.Full Text Link to Item
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Levin, E. D., S. J. Briggs, N. C. Christopher, and J. E. Rose. “Prenatal nicotine exposure and cognitive performance in rats.” Neurotoxicol Teratol 15, no. 4 (July 1993): 251–60. https://doi.org/10.1016/0892-0362(93)90006-a.Full Text Link to Item
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Levin, E. D. “Development of treatments for toxicant-induced cognitive deficits.” Neurotoxicol Teratol 15, no. 3 (May 1993): 203–6. https://doi.org/10.1016/0892-0362(93)90016-h.Full Text Link to Item
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Levin, E. D., S. J. Briggs, N. C. Christopher, and J. E. Rose. “Chronic nicotinic stimulation and blockade effects on working memory.” Behav Pharmacol 4, no. 2 (April 1993): 179–82.Link to Item
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Rose, J. E., F. M. Behm, and E. D. Levin. “Role of nicotine dose and sensory cues in the regulation of smoke intake.” Pharmacol Biochem Behav 44, no. 4 (April 1993): 891–900. https://doi.org/10.1016/0091-3057(93)90021-k.Full Text Link to Item
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WESTMAN, E. C., D. L. SIMEL, E. D. LEVIN, and J. E. ROSE. “PREDICTING SUCCESS OF THE NICOTINE PATCH IN SMOKING CESSATION USING BASE-LINE CLINICAL INFORMATION.” Clinical Research 41, no. 2 (April 1, 1993): A573–A573.Link to Item
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WESTMAN, E. C., E. D. LEVIN, and J. E. ROSE. “SMOKING WHILE WEARING THE NICOTINE PATCH - IS SMOKING STILL SATISFYING.” Clinical Research 41, no. 2 (April 1, 1993): A573–A573.Link to Item
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Behm, F. M., C. Schur, E. D. Levin, D. P. Tashkin, and J. E. Rose. “Clinical evaluation of a citric acid inhaler for smoking cessation.” Drug Alcohol Depend 31, no. 2 (January 1993): 131–38. https://doi.org/10.1016/0376-8716(93)90065-x.Full Text Link to Item
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Levin, E. D., S. J. Briggs, N. C. Christopher, and J. E. Rose. “Sertraline attenuates hyperphagia in rats following nicotine withdrawal.” Pharmacol Biochem Behav 44, no. 1 (January 1993): 51–61. https://doi.org/10.1016/0091-3057(93)90280-7.Full Text Link to Item
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Levin, E. D., and F. J. Seidler. “Sex-related spatial learning differences after prenatal cocaine exposure in the young adult rat.” Neurotoxicology 14, no. 1 (1993): 23–28.Link to Item
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WESTMAN, E. C., D. L. SIMEL, E. D. LEVIN, and J. E. ROSE. “DERIVATION OF A LOGISTIC MODEL USING BASE-LINE CLINICAL INFORMATION TO PREDICT SUCCESS WITH THE NICOTINE PATCH IN SMOKING CESSATION.” Clinical Research 40, no. 4 (December 1, 1992): A811–A811.Link to Item
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WESTMAN, E. C., E. D. LEVIN, and J. E. ROSE. “SMOKING WHILE WEARING THE NICOTINE PATCH - IS SMOKING SATISFYING OR HARMFUL.” Clinical Research 40, no. 4 (December 1, 1992): A871–A871.Link to Item
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Seidler, F. J., E. D. Levin, S. E. Lappi, and T. A. Slotkin. “Fetal nicotine exposure ablates the ability of postnatal nicotine challenge to release norepinephrine from rat brain regions.” Brain Res Dev Brain Res 69, no. 2 (October 23, 1992): 288–91. https://doi.org/10.1016/0165-3806(92)90170-2.Full Text Link to Item
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Uemura, E., and E. D. Levin. “The effect of halothane on cultured fibroblasts and neuroblastoma cells.” Neurosci Lett 145, no. 1 (September 28, 1992): 33–36. https://doi.org/10.1016/0304-3940(92)90196-e.Full Text Link to Item
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Levin, E. D., S. J. Briggs, N. C. Christopher, and J. E. Rose. “Persistence of chronic nicotine-induced cognitive facilitation.” Behav Neural Biol 58, no. 2 (September 1992): 152–58. https://doi.org/10.1016/0163-1047(92)90399-o.Full Text Link to Item
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McGurk, S. R., E. D. Levin, and L. L. Butcher. “Dopaminergic drugs reverse the impairment of radial-arm maze performance caused by lesions involving the cholinergic medial pathway.” Neuroscience 50, no. 1 (September 1992): 129–35. https://doi.org/10.1016/0306-4522(92)90387-h.Full Text Link to Item
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Levin, E. D., S. L. Schantz, and R. E. Bowman. “Use of the lesion model for examining toxicant effects on cognitive behavior.” Neurotoxicol Teratol 14, no. 2 (March 1992): 131–41. https://doi.org/10.1016/0892-0362(92)90061-e.Full Text Link to Item
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Henningfield, J. E., E. Obarzanek, N. L. Benowitz, S. M. Hall, R. C. Klesges, S. Leischow, E. D. Levin, K. A. Perkins, B. Spring, and M. Stitzer. “National working conference on smoking and body weight. Task Force 2: Methods of assessment, strategies for research.” Health Psychol 11 Suppl (1992): 10–16.Link to Item
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LEVIN, E. D. “ANIMAL-MODELS OF NICOTINE EFFECTS ON WEIGHT REGULATION.” Health Psychology 11 (January 1, 1992): 40–40.Link to Item
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Levin, E. D. “Nicotinic systems and cognitive function.” Psychopharmacology (Berl) 108, no. 4 (1992): 417–31. https://doi.org/10.1007/BF02247415.Full Text Link to Item
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Levin, E., S. L. Schantz, and R. E. Bowman. “Erratum: Use of the lesion model for examining toxicant effects on cognitive behavior (Neurotoxicol. Teratol. 14 (131-142) 1992).” Neurotoxicology and Teratology 14, no. 4 (January 1, 1992): 298. https://doi.org/10.1016/0892-0362(92)90010-8.Full Text
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Rose, J. E., and E. D. Levin. “Concurrent agonist-antagonist administration for the analysis and treatment of drug dependence.” Pharmacol Biochem Behav 41, no. 1 (January 1992): 219–26. https://doi.org/10.1016/0091-3057(92)90086-u.Full Text Link to Item
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Levin, E. D., E. Uemura, and R. E. Bowman. “Neurobehavioral toxicology of halothane in rats.” Neurotoxicol Teratol 13, no. 4 (July 1991): 461–70. https://doi.org/10.1016/0892-0362(91)90096-f.Full Text Link to Item
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Levin, E. D., and J. E. Rose. “Nicotinic and muscarinic interactions and choice accuracy in the radial-arm maze.” Brain Res Bull 27, no. 1 (July 1991): 125–28. https://doi.org/10.1016/0361-9230(91)90293-s.Full Text Link to Item
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Levin, E. D., J. E. Rose, F. Behm, and N. H. Caskey. “The effects of smoking-related sensory cues on psychological stress.” Pharmacol Biochem Behav 39, no. 2 (June 1991): 265–68. https://doi.org/10.1016/0091-3057(91)90177-4.Full Text Link to Item
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Rose, J. E., and E. D. Levin. “Inter-relationships between conditioned and primary reinforcement in the maintenance of cigarette smoking.” Br J Addict 86, no. 5 (May 1991): 605–9. https://doi.org/10.1111/j.1360-0443.1991.tb01816.x.Full Text Link to Item
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Levin, E. D., and J. E. Rose. “Interactive effects of D1 and D2 agonists with scopolamine on radial-arm maze performance.” Pharmacol Biochem Behav 38, no. 2 (February 1991): 243–46. https://doi.org/10.1016/0091-3057(91)90272-4.Full Text Link to Item
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McGurk, S. R., E. D. Levin, and L. L. Butcher. “Impairment of radial-arm maze performance in rats following lesions involving the cholinergic medial pathway: reversal by arecoline and differential effects of muscarinic and nicotinic antagonists.” Neuroscience 44, no. 1 (1991): 137–47. https://doi.org/10.1016/0306-4522(91)90256-n.Full Text Link to Item
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Schantz, S. L., E. D. Levin, and R. E. Bowman. “Long‐term neurobehavioral effects of perinatal polychlorinated biphenyl (PCB) exposure in monkeys.” Environmental Toxicology and Chemistry 10, no. 6 (January 1, 1991): 747–56. https://doi.org/10.1002/etc.5620100606.Full Text
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Levin, E. D., S. R. McGurk, J. E. Rose, and L. L. Butcher. “Cholinergic-dopaminergic interactions in cognitive performance.” Behav Neural Biol 54, no. 3 (November 1990): 271–99. https://doi.org/10.1016/0163-1047(90)90639-n.Full Text Link to Item
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Grijalva, C. V., E. D. Levin, M. Morgan, B. Roland, and F. C. Martin. “Contrasting effects of centromedial and basolateral amygdaloid lesions on stress-related responses in the rat.” Physiol Behav 48, no. 4 (October 1990): 495–500. https://doi.org/10.1016/0031-9384(90)90289-g.Full Text Link to Item
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Levin, E. D., F. Behm, and J. E. Rose. “The use of flavor in cigarette substitutes.” Drug Alcohol Depend 26, no. 2 (October 1990): 155–60. https://doi.org/10.1016/0376-8716(90)90122-u.Full Text Link to Item
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Levin, E. D., J. E. Rose, and F. Behm. “Development of a citric acid aerosol as a smoking cessation aid.” Drug Alcohol Depend 25, no. 3 (June 1990): 273–79. https://doi.org/10.1016/0376-8716(90)90152-5.Full Text Link to Item
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Levin, E. D., C. Lee, J. E. Rose, A. Reyes, G. Ellison, M. Jarvik, and E. Gritz. “Chronic nicotine and withdrawal effects on radial-arm maze performance in rats.” Behav Neural Biol 53, no. 2 (March 1990): 269–76. https://doi.org/10.1016/0163-1047(90)90509-5.Full Text Link to Item
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Rose, J. E., E. D. Levin, F. M. Behm, C. Adivi, and C. Schur. “Transdermal nicotine facilitates smoking cessation.” Clin Pharmacol Ther 47, no. 3 (March 1990): 323–30. https://doi.org/10.1038/clpt.1990.35.Full Text Link to Item
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Behm, F. M., E. D. Levin, Y. K. Lee, and J. E. Rose. “Low-nicotine regenerated smoke aerosol reduces desire for cigarettes.” J Subst Abuse 2, no. 2 (1990): 237–47. https://doi.org/10.1016/s0899-3289(05)80058-6.Full Text Link to Item
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Levin, E. D., J. E. Rose, S. R. McGurk, and L. L. Butcher. “Characterization of the cognitive effects of combined muscarinic and nicotinic blockade.” Behav Neural Biol 53, no. 1 (January 1990): 103–12. https://doi.org/10.1016/0163-1047(90)90865-4.Full Text Link to Item
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Levin, E. D., P. J. Bushnell, and C. M. Baysinger. “d-Amphetamine-induced "floating limb" syndrome in young rhesus monkeys.” Psychopharmacology (Berl) 101, no. 1 (1990): 112–17. https://doi.org/10.1007/BF02253727.Full Text Link to Item
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Levin, E. D., R. DeLuna, E. Uemura, and R. E. Bowman. “Long-term effects of developmental halothane exposure on radial arm maze performance in rats.” Behav Brain Res 36, no. 1–2 (January 1, 1990): 147–54. https://doi.org/10.1016/0166-4328(90)90168-e.Full Text Link to Item
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Levin, E. D., and J. E. Rose. “Anticholinergic sensitivity following chronic nicotine administration as measured by radial-arm maze performance in rats.” Behav Pharmacol 1, no. 6 (1990): 511–20.Link to Item
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Uemura, E., E. D. Levin, R. DeLuna, and R. E. Bowman. “Suppressive effects of halothane on reactive synaptogenesis in the dentate gyrus of rats.” Brain Res 496, no. 1–2 (September 4, 1989): 317–20. https://doi.org/10.1016/0006-8993(89)91080-9.Full Text Link to Item
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Levin, E. D., R. E. See, and D. South. “Effects of dopamine D1 and D2 receptor antagonists on oral activity in rats.” Pharmacol Biochem Behav 34, no. 1 (September 1989): 43–48. https://doi.org/10.1016/0091-3057(89)90350-x.Full Text Link to Item
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Levin, E. D., S. R. McGurk, J. E. Rose, and L. L. Butcher. “Reversal of a mecamylamine-induced cognitive deficit with the D2 agonist, LY 171555.” Pharmacol Biochem Behav 33, no. 4 (August 1989): 919–22. https://doi.org/10.1016/0091-3057(89)90494-2.Full Text Link to Item
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Levin, E. D., G. D. Ellison, R. E. See, D. South, and E. Young. “D1 and D2 dopamine receptor interactions with pilocarpine-induced oral activity in rats.” Pharmacol Biochem Behav 33, no. 3 (July 1989): 501–5. https://doi.org/10.1016/0091-3057(89)90376-6.Full Text Link to Item
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McGurk, S. R., E. D. Levin, and L. L. Butcher. “Nicotinic-dopaminergic relationships and radial-arm maze performance in rats.” Behav Neural Biol 52, no. 1 (July 1989): 78–86. https://doi.org/10.1016/s0163-1047(89)90182-9.Full Text Link to Item
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Levin, E. D., J. E. Rose, and F. Behm. “Controlling puff volume without disrupting smoking topography.” Behavior Research Methods, Instruments, &Amp; Computers 21, no. 3 (May 1, 1989): 383–86. https://doi.org/10.3758/BF03202801.Full Text
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Schantz, S. L., E. D. Levin, R. E. Bowman, M. P. Heironimus, and N. K. Laughlin. “Effects of perinatal PCB exposure on discrimination-reversal learning in monkeys.” Neurotoxicol Teratol 11, no. 3 (May 1989): 243–50. https://doi.org/10.1016/0892-0362(89)90066-4.Full Text Link to Item
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Rose, J. E., A. Sampson, E. D. Levin, and J. E. Henningfield. “Mecamylamine increases nicotine preference and attenuates nicotine discrimination.” Pharmacol Biochem Behav 32, no. 4 (April 1989): 933–38. https://doi.org/10.1016/0091-3057(89)90061-0.Full Text Link to Item
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Levin, E. D., S. R. McGurk, D. South, and L. L. Butcher. “Effects of combined muscarinic and nicotinic blockade on choice accuracy in the radial-arm maze.” Behav Neural Biol 51, no. 2 (March 1989): 270–77. https://doi.org/10.1016/s0163-1047(89)90917-5.Full Text Link to Item
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Andersson, U., J. E. Häggström, E. D. Levin, U. Bondesson, M. Valverius, and L. M. Gunne. “Reduced glutamate decarboxylase activity in the subthalamic nucleus in patients with tardive dyskinesia.” Mov Disord 4, no. 1 (1989): 37–46. https://doi.org/10.1002/mds.870040107.Full Text Link to Item
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Levin, E. D., and L. M. Gunne. “Chronic neuroleptic effects on spatial reversal learning in monkeys.” Psychopharmacology (Berl) 97, no. 4 (1989): 496–500. https://doi.org/10.1007/BF00439554.Full Text Link to Item
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McGurk, S. R., E. D. Levin, and L. L. Butcher. “Radial-arm maze performance in rats is impaired by a combination of nicotinic-cholinergic and D2 dopaminergic antagonist drugs.” Psychopharmacology (Berl) 99, no. 3 (1989): 371–73. https://doi.org/10.1007/BF00445560.Full Text Link to Item
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Yirmiya, R., E. D. Levin, C. D. Chapman, and J. Garcia. “Morphological and behavioral effects of perinatal exposure to aspartame (Nutrasweet®) on rat pups.” Bulletin of the Psychonomic Society 27, no. 2 (January 1, 1989): 153–56. https://doi.org/10.3758/BF03329926.Full Text
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Levin, E. D., and R. E. Bowman. “Long-term effects of chronic postnatal lead exposure on delayed spatial alternation in monkeys.” Neurotoxicol Teratol 10, no. 6 (November 1988): 505–10. https://doi.org/10.1016/0892-0362(88)90085-2.Full Text Link to Item
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Gunne, L. M., J. E. Häggström, P. Johansson, E. D. Levin, and L. Terenius. “Neurobiochemical changes in tardive dyskinesia.” Encephale 14 Spec No (September 1988): 167–73.Link to Item
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Levin, E. D. “Scopolamine interactions with D1 and D2 antagonists on radial-arm maze performance in rats.” Behav Neural Biol 50, no. 2 (September 1988): 240–45. https://doi.org/10.1016/s0163-1047(88)90911-9.Full Text Link to Item
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Levin, E. D., M. L. Schneider, S. A. Ferguson, S. L. Schantz, and R. E. Bowman. “Behavioral effects of developmental lead exposure in rhesus monkeys.” Dev Psychobiol 21, no. 4 (May 1988): 371–82. https://doi.org/10.1002/dev.420210408.Full Text Link to Item
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McGurk, S. R., E. D. Levin, and L. L. Butcher. “Cholinergic-dopaminergic interactions in radial-arm maze performance.” Behav Neural Biol 49, no. 2 (March 1988): 234–39. https://doi.org/10.1016/s0163-1047(88)90539-0.Full Text Link to Item
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Ellison, G., P. Johansson, E. Levin, R. See, and L. Gunne. “Chronic neuroleptics alter the effects of the D1 agonist SK&F 38393 and the D2 agonist LY171555 on oral movements in rats.” Psychopharmacology (Berl) 96, no. 2 (1988): 253–57. https://doi.org/10.1007/BF00177570.Full Text Link to Item
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Levin, E. D. “Psychopharmacological effects in the radial-arm maze.” Neurosci Biobehav Rev 12, no. 2 (1988): 169–75. https://doi.org/10.1016/s0149-7634(88)80008-3.Full Text Link to Item
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Levin, E. D., G. D. Ellison, C. Salem, M. Jarvik, and E. Gritz. “Behavioral effects of acute hexamethonium in rats chronically intoxicated with nicotine.” Physiol Behav 44, no. 3 (1988): 355–59. https://doi.org/10.1016/0031-9384(88)90037-6.Full Text Link to Item
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Levin, E. D., S. L. Schantz, and R. E. Bowman. “Delayed spatial alternation deficits resulting from perinatal PCB exposure in monkeys.” Arch Toxicol 62, no. 4 (1988): 267–73. https://doi.org/10.1007/BF00332486.Full Text Link to Item
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See, R. E., E. D. Levin, and G. D. Ellison. “Characteristics of oral movements in rats during and after chronic haloperidol and fluphenazine administration.” Psychopharmacology (Berl) 94, no. 3 (1988): 421–27. https://doi.org/10.1007/BF00174701.Full Text Link to Item
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Levin, E. D., E. Uemura, R. DeLuna, P. Franks, and R. E. Bowman. “Neurobehavioral effects of chronic halothane exposure during developmental and juvenile periods in the rat.” Exp Neurol 98, no. 3 (December 1987): 584–93. https://doi.org/10.1016/0014-4886(87)90267-6.Full Text Link to Item
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Levy, A. D., R. E. See, E. D. Levin, and G. D. Ellison. “Neuroleptic-induced oral movements in rats: methodological issues.” Life Sci 41, no. 12 (September 21, 1987): 1499–1506. https://doi.org/10.1016/0024-3205(87)90715-6.Full Text Link to Item
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Levin, E. D., M. Castonguay, and G. D. Ellison. “Effects of the nicotinic receptor blocker mecamylamine on radial-arm maze performance in rats.” Behav Neural Biol 48, no. 2 (September 1987): 206–12. https://doi.org/10.1016/s0163-1047(87)90752-7.Full Text Link to Item
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Morgan, M. M., E. D. Levin, and J. C. Liebeskind. “Characterization of the analgesic effects of the benzodiazepine antagonist, Ro 15-1788.” Brain Res 415, no. 2 (July 14, 1987): 367–70. https://doi.org/10.1016/0006-8993(87)90222-8.Full Text Link to Item
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Johansson, P., E. Levin, L. Gunne, and G. Ellison. “Opposite effects of a D1 and a D2 agonist on oral movements in rats.” Eur J Pharmacol 134, no. 1 (January 28, 1987): 83–88. https://doi.org/10.1016/0014-2999(87)90134-8.Full Text Link to Item
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Ellison, G., R. See, E. Levin, and J. Kinney. “Tremorous mouth movements in rats administered chronic neuroleptics.” Psychopharmacology (Berl) 92, no. 1 (1987): 122–26. https://doi.org/10.1007/BF00215492.Full Text Link to Item
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Levin, E. D., D. M. Galen, and G. D. Ellison. “Chronic haloperidol effects on oral movements and radial-arm maze performance in rats.” Pharmacol Biochem Behav 26, no. 1 (January 1987): 1–6. https://doi.org/10.1016/0091-3057(87)90523-5.Full Text Link to Item
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Levin, E. D., M. M. Morgan, C. Galvez, and G. D. Ellison. “Chronic nicotine and withdrawal effects on body weight and food and water consumption in female rats.” Physiol Behav 39, no. 4 (1987): 441–44. https://doi.org/10.1016/0031-9384(87)90370-2.Full Text Link to Item
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Levin, E. D., R. E. Bowman, S. Wegert, and J. Vuchetich. “Psychopharmacological investigations of a lead-induced long-term cognitive deficit in monkeys.” Psychopharmacology (Berl) 91, no. 3 (1987): 334–41. https://doi.org/10.1007/BF00518187.Full Text Link to Item
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Lubischer, J. L., R. E. See, E. D. Levin, and J. C. Liebeskind. “The effects of D1 and D2 receptor antagonists on pain sensitivity and morphine analgesia in the rat.” Proc West Pharmacol Soc 30 (1987): 229–32.Link to Item
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Levin, E. D., and R. E. Bowman. “Effects of the dopamine D-2 receptor agonist, LY 171555, on radial arm maze performance in rats.” Pharmacol Biochem Behav 25, no. 5 (November 1986): 1117–19. https://doi.org/10.1016/0091-3057(86)90095-x.Full Text Link to Item
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Levin, E. D., and R. E. Bowman. “Behavioral effects of chronic exposure to low concentrations of halothane during development in rats.” Anesth Analg 65, no. 6 (June 1986): 653–59.Link to Item
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Levin, E. D., and R. E. Bowman. “Long-term lead effects on the Hamilton Search Task and delayed alternation in monkeys.” Neurobehav Toxicol Teratol 8, no. 3 (May 1986): 219–24.Link to Item
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Levin, E. D., and R. E. Bowman. “Scopolamine effects on Hamilton search task performance in monkeys.” Pharmacol Biochem Behav 24, no. 4 (April 1986): 819–21. https://doi.org/10.1016/0091-3057(86)90417-x.Full Text Link to Item
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Mele, P. C., R. E. Bowman, and E. D. Levin. “Behavioral evaluation of perinatal PCB exposure in rhesus monkeys: fixed-interval performance and reinforcement-omission.” Neurobehav Toxicol Teratol 8, no. 2 (March 1986): 131–38.Link to Item
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Levin, E. D., K. M. Boehm, W. W. Hagquist, and R. E. Bowman. “A visual exploration apparatus for infant monkeys.” American Journal of Primatology 10, no. 2 (January 1, 1986): 195–99. https://doi.org/10.1002/ajp.1350100209.Full Text
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Morgan, M. M., E. D. Levin, and J. C. Liebeskind. “Analgesia produced by the benzodiazepine antagonist R015-1788.” Proceedings of the Western Pharmacology Society VOL. 29 (January 1, 1986): 237–40.
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Weinstein, D. L., G. D. Ellison, R. See, and E. Levin. “A model for tardive dyskinesia: The effects of chronic fluphenazine decanoate on guinea pigs.” Proceedings of the Western Pharmacology Society VOL. 29 (January 1, 1986): 405–7.
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Uemura, E., E. D. Levin, and R. E. Bowman. “Effects of halothane on synaptogenesis and learning behavior in rats.” Exp Neurol 89, no. 3 (September 1985): 520–29. https://doi.org/10.1016/0014-4886(85)90003-2.Full Text Link to Item
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Uemura, E., W. P. Ireland, E. D. Levin, and R. E. Bowman. “Effects of halothane on the development of rat brain: a golgi study of dendritic growth.” Exp Neurol 89, no. 3 (September 1985): 503–19. https://doi.org/10.1016/0014-4886(85)90002-0.Full Text Link to Item
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Bushnell, P. J., and E. D. Levin. “Effects of zinc deficiency on lead toxicity in rats.” Neurobehav Toxicol Teratol 5, no. 3 (May 1983): 283–88.Link to Item
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Levin, E. D., and R. E. Bowman. “The effect of pre- or postnatal lead exposure on Hamilton Search Task in monkeys.” Neurobehav Toxicol Teratol 5, no. 3 (May 1983): 391–94.Link to Item
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Strongin, A. Y., E. D. Levin, and V. M. Stepanov. “Isoelectric focusing of proteins in gels.” Chemistry of Natural Compounds 9, no. 5 (September 1, 1973): 551–64. https://doi.org/10.1007/BF00564370.Full Text
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Book Sections
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Hawkey, A. B., Z. Holloway, and E. D. Levin. “A Behavioral Test Battery to Assess Larval and Adult Zebrafish After Developmental Neurotoxic Exposure.” In Neuromethods, 172:353–80, 2021. https://doi.org/10.1007/978-1-0716-1637-6_16.Full Text
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Rezvani, A. H., S. D. Glick, and E. D. Levin. “Oral 18-Methoxycoronaridine (18-MC) Decreases Nicotine Self-Administration in Rats.” In Neuroscience of Nicotine: Mechanisms and Treatment, 493–97, 2019. https://doi.org/10.1016/B978-0-12-813035-3.00059-9.Full Text
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Abreu-Villaça, Y., and E. D. Levin. “Developmental neurobehavioral neurotoxicity of insecticides.” In Handbook of Developmental Neurotoxicology, 453–66, 2018. https://doi.org/10.1016/B978-0-12-809405-1.00040-7.Full Text
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Levin, E. D. “Chronic Nicotine Effects on Memory and Nicotine Self-Administration: Age of Exposure is Key.” In Advances in Neurotoxicology, 2:189–96, 2018. https://doi.org/10.1016/bs.ant.2018.03.003.Full Text
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Levin, E. D., and Y. Abreu-Villaça. “Developmental neurotoxicity of nicotine and tobacco.” In Handbook of Developmental Neurotoxicology, 439–52, 2018. https://doi.org/10.1016/B978-0-12-809405-1.00039-0.Full Text
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Cerutti, D. T., and E. D. Levin. “Cognitive impairment models using complementary species.” In Animal Models of Cognitive Impairment, 315–42, 2006.
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Levin, E. D., and J. J. Buccafusco. “Introduction.” In Animal Models of Cognitive Impairment, 1–2, 2006.
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Roegge, C. S., and E. D. Levin. “Nicotinic receptor antagonists in rats.” In Animal Models of Cognitive Impairment, 21–35, 2006.
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Levin, E. D., and A. H. Rezvani. “Nicotinic involvement in cognitive function of rats.” In Nicotinic Receptors in the Nervous System, 167–78, 2001.
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Levin, E. D. “Nicotinic systems: An integrated approach.” In Nicotinic Receptors in the Nervous System, 281–82, 2001.
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Levin, E. D. “Nicotine effects on attention deficit hyperactivity disorder.” In Nicotinic Receptors in the Nervous System, 251–60, 2001.
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Levin, E. D. “Use of the radial-arm maze to assess learning and memory in rodents.” In Methods of Behavior Analysis in Neuroscience, 189–99, 2000.
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Conference Papers
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Levin, E. D. “What Can Fish Tell Us About Developmental Neurotoxic Risks of the Sea?” In Birth Defects Research, 111:454–454. WILEY, 2019.Link to Item
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Kollins, Scott, Ed Levin, Tom Price, and Susan Murphy. “Delta-9-Tetrahydrocannabinol Exposure Alters Sperm Methylation Profiles: Concurrent Results From Humans and Rats.” In Neuropsychopharmacology, 42:S642–43. NATURE PUBLISHING GROUP, 2017.Link to Item
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Murphy, S. K., R. Schrott, Z. Visco, Z. Huang, C. Grenier, J. Mitchell, J. Schechter, et al. “Environment and Gametic Epigenetic Reprogramming.” In Environmental and Molecular Mutagenesis, 58:S28–S28. WILEY, 2017.Link to Item
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Levin, Edward D. “Neurodevelopmental Toxicity of Tobacco Smoke and Nicotine.” In Neurotoxicology and Teratology, 61:153–153. PERGAMON-ELSEVIER SCIENCE LTD, 2017.Link to Item
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Murphy, S. K., S. Keyhan, L. Guo, K. Tomins, M. Taylor, R. Joglekar, Z. Huang, et al. “Environmental Influence on Preconceptional and Gestational DNA Methylation Profiles.” In Environmental and Molecular Mutagenesis, 57:S39–S39. WILEY-BLACKWELL, 2016.Link to Item
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Levin, Edward D., Amir H. Rezvani, Yingxian Xiao, Venkata M. Yenugonda, Milton L. Brown, and Kenneth J. Kellar. “Nicotinic treatments not only for tobacco, but also other addictions.” In Biochemical Pharmacology, 97:635–635. Elsevier BV, 2015. https://doi.org/10.1016/j.bcp.2015.08.040.Full Text
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Bailey, Jordan, and Ed Levin. “The neurobehavioral toxicity of FireMaster 550® in zebrafish ( Danio rerio ): Chronic developmental and acute adolescent exposures.” In Neurotoxicology and Teratology, 49:118–118. Elsevier BV, 2015. https://doi.org/10.1016/j.ntt.2015.04.064.Full Text
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Hall, Brandon J., Marty Cauley, Abtin Kiany, Dennis A. Burke, and Edward D. Levin. “Low dose tobacco smoke extract exposure during development causes long-term behavioral dysfunction in rats.” In Neurotoxicology and Teratology, 49:121–22. Elsevier BV, 2015. https://doi.org/10.1016/j.ntt.2015.04.073.Full Text
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Levin, Edward D. “Age and sex differences in starting nicotine self-administration in early, mid or late adolescence vs. adulthood: Cause and effect relationships determined in a rat model.” In Neurotoxicology and Teratology, 49:140–140. Elsevier BV, 2015. https://doi.org/10.1016/j.ntt.2015.04.128.Full Text
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Oliveri, Anthony, and Ed Levin. “Early-life exposure to organophosphate flame retardants alters behavior in adult zebrafish: A comparison with organophosphate pesticides.” In Neurotoxicology and Teratology, 49:130–130. Elsevier BV, 2015. https://doi.org/10.1016/j.ntt.2015.04.096.Full Text
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Rezvani, Amir H., and Edward D. Levin. “Assessment of pregnenolone effects on alcohol intake and preference in male alcohol preferring (P) rats.” In Eur J Pharmacol, 740:53–57, 2014. https://doi.org/10.1016/j.ejphar.2014.07.003.Full Text Link to Item
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Zhang, C., J. M. Bailey, A. N. Oliveri, J. Frazier, A. Delarosa, E. Crosby, S. Janardhan, S. Mackinnon, E. D. Levin, and G. J. Cole. “LONG-TERM BEHAVIORAL EFFECTS OF EMBRYONIC ETHANOL EXPOSURE IN ZEBRAFISH.” In Alcoholism Clinical and Experimental Research, 38:176A-176A. WILEY-BLACKWELL, 2014.Link to Item
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Cauley, M., D. Burke, B. J. Hall, F. J. Seidler, T. A. Slotkin, and E. D. Levin. “Sex-selective interaction of prenatal nicotine with neonatal chlorpyrifos on novel object recognition in rats.” In Neurotoxicology and Teratology, 43:88–89. Elsevier BV, 2014. https://doi.org/10.1016/j.ntt.2014.04.043.Full Text
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Burke, Dennis, and Edward D. Levin. “Nicotinic α4β2 antagonist treatment attenuates impairments in radial-arm maze repeated acquisition caused by dizocilpine in rats.” In Biochemical Pharmacology, 86:1231–1231. Elsevier BV, 2013. https://doi.org/10.1016/j.bcp.2013.08.047.Full Text
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Rezvani, A. H., Y. Xiao, M. L. Brown, M. A. Paige, V. M. Yenugonda, K. J. Kellar, and E. D. Levin. “DESENSITIZATION OF A4 beta 2 NICOTINIC RECEPTORS ATTENUATES ALCOHOL INTAKE AND PREFERENCE IN ALCOHOL PREFERRING P RATS.” In Alcoholism Clinical and Experimental Research, 37:247A-247A. WILEY-BLACKWELL, 2013.Link to Item
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Yenugonda, Venkata M., Yingxian Xiao, Edward D. Levin, Amir H. Rezvani, Thao T. Tran, Nour Al-Muhtasib, Corinne Wells, et al. “Design, synthesis, and characterization of picomolar selective a4b2 nicotinic acetylcholine receptor inhibitors.” In Abstracts of Papers of the American Chemical Society, Vol. 244. AMER CHEMICAL SOC, 2012.Link to Item
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Galici, R., A. H. Rezvani, L. Aluisio, B. Lord, E. D. Levin, I. Fraser, J. Boggs, et al. “JNJ-39220675, A NOVEL SELECTIVE HISTAMINE H-3 RECEPTOR ANTAGONIST, REDUCES THE ABUSE-RELATED EFFECTS OF ALCOHOL IN RATS.” In Inflammation Research, 60:S333–S333. SPRINGER BASEL AG, 2011.Link to Item
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Yen, Jerry, Sue Donerly, Ed Levin, and Elwood Linney. “Differing Effects of 3 Organophosphates (Chlorpyrifos, Diazinon and Parathion) on Developing Zebrafish Nervous System.” In Neurotoxicology and Teratology, 33:509–10. Elsevier BV, 2011. https://doi.org/10.1016/j.ntt.2011.05.062.Full Text
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Rezvani, A. H., E. Robinson, L. Eisenberg, E. D. Levin, P. Bonaventure, T. Motley, T. W. Lovenberg, M. Heilig, A. Thorsell, and A. Cippitelli. “EFFECTS OF A NOVEL, SELECTIVE BRAIN NPY Y2 RECPTOR ANATONIST JNJ-31020028, ON ALCOHOL CONSUMPTION, RELAPSE AND ANXIETY IN RATS.” In Alcoholism Clinical and Experimental Research, 35:68A-68A. WILEY-BLACKWELL, 2011.Link to Item
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Rezvani, A. H., L. Lumeng, T. K. Li, Y. Xiao, M. L. Brown, M. A. Paige, B. E. McDowell, J. E. Rose, K. J. Kellar, and E. D. Levin. “NICOTINE SELF-ADMINISTRATION IN SELECTIVELY-BRED ALCOHOL PREFERRING (P) RATS: NICOTINIC INVOLVEMENT.” In Alcoholism Clinical and Experimental Research, 34:18A-18A. WILEY-BLACKWELL PUBLISHING, INC, 2010.Link to Item
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Levin, Edward D., Dawn Hampton, Yingxian Xiao, and Kenneth J. Kellar. “Sazetidine-A, a nicotinic desensitizing agent, decreases nicotine self-administration in rats.” In Biochemical Pharmacology, 74:SMA43–44. PERGAMON-ELSEVIER SCIENCE LTD, 2007.Link to Item
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Levin, E. D., E. Linney, and T. A. Slotkin. “Complementary zebrafish and rat models of developmental neurobehavioral toxicity: The case of organophosphate pesticide exposure.” In Neurotoxicology and Teratology, 29:406–406. Elsevier BV, 2007. https://doi.org/10.1016/j.ntt.2007.03.038.Full Text
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Levin, Edward D. “Nicotinic treatment for both symptomatic relief and attenuation of cognitive decline with aging and Alzheimer's dementia.” In Neurotoxicology, 27:1162–1162. ELSEVIER SCIENCE BV, 2006.Link to Item
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Levin, Edward D., Cindy Roegge, Olga Timofeeva, Frederic J. Seidler, and Theodore A. Slotkin. “Low dose early postnatal diazinon exposure causes impaired working memory on the radial-arm maze in rats during adulthood.” In Neurotoxicology, 27:1165–1165. ELSEVIER SCIENCE BV, 2006.Link to Item
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Levin, Edward D., Zachary Bencan, and Daniel T. Cerutti. “Assessing stress in zebrafish: Anxiolytic effects of nicotine.” In Neurotoxicology and Teratology, 28:709–10. Elsevier BV, 2006. https://doi.org/10.1016/j.ntt.2006.09.016.Full Text
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Roegge, Cindy, Olga Timofeva, Frederic Seidler, Theodore A. Slotkin, and Edward D. Levin. “Persisting effects of early postnatal diazinon exposure on emotional reactivity in rats.” In Neurotoxicology and Teratology, 28:709–709. Elsevier BV, 2006. https://doi.org/10.1016/j.ntt.2006.09.015.Full Text
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Levin, Edward D. “Cholinergic involvement in neurocognitive function: From zebrafish to humans.” In Neurotoxicology, 27:892–93. ELSEVIER SCIENCE BV, 2006.Link to Item
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Levin, E. D. “Developing nicotinic therapy for cognitive impairment of schizophrenia and aging-related dementia.” In International Journal of Neuropsychopharmacology, 9:S126–S126. CAMBRIDGE UNIV PRESS, 2006.Link to Item
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Rezvani, A. H., and E. D. Levin. “Nicotine-antipsychotic drugs interaction and sustained attention in rats.” In International Journal of Neuropsychopharmacology, 9:S146–S146. CAMBRIDGE UNIV PRESS, 2006.Link to Item
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Levin, E. D. “Clozapine effects on memory function are reversed by hippocampal damage.” In Neuropsychopharmacology, 30:S197–S197. NATURE PUBLISHING GROUP, 2005.Link to Item
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Levin, E. D., and A. H. Rezvani. “Adolescent rats show differential effects of nicotine and alcohol relative to adults.” In Alcoholism Clinical and Experimental Research, 28:175A-175A. LIPPINCOTT WILLIAMS & WILKINS, 2004.Link to Item
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Weiser, M., E. D. Levin, T. P. George, P. A. Newhouse, and S. Leonard. “Nicotinic receptor modulation of attention: An endophenotype for therapeutic drug development.” In Biological Psychiatry, 55:152S-152S. ELSEVIER SCIENCE INC, 2004.Link to Item
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Levin, E. D., W. R. Blackwelder, H. B. Glasgow, J. M. Burkholder, P. R. Moeller, and J. S. Ramsdell. “Learning impairment caused by infusion of a toxin produced by Pfiesteria piscicida into the hippocampus of rats.” In Toxicological Sciences, 72:71–71. OXFORD UNIV PRESS, 2003.Link to Item
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Swain, H., S. Donerly, E. Chrysanthis, K. Yacsin, E. Linney, and E. D. Levin. “A zebrafish model for studying the neurobehavioral impacts of developmental chlorpyrifos exposure.” In Toxicological Sciences, 72:129–129. OXFORD UNIV PRESS, 2003.Link to Item
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LEVIN, E. D., and D. TORRY. “NICOTINE EFFECTS ON MEMORY PERFORMANCE.” In Effects of Nicotine on Biological Systems Ii, edited by P. B. S. Clarke, M. Quik, F. Adlkofer, and K. Thurau, 329–35. BIRKHAUSER VERLAG AG, 1995.Link to Item
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Datasets
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Schrott, Rose, Douglas Raburn, Scott Kollins, Edward Levin, David Corcoran, Marie-Helene Boudreau, Zhiqing Huang, et al. “Data from: Cannabinoid exposure and altered DNA methylation in rat and human sperm,” August 25, 2020. https://doi.org/10.7924/r4v122j79.Data Access
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- Teaching & Mentoring
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Recent Courses
- PHARM 394: Research Independent Study 2022
- PHARM 494: Research Independent Study 2022
- NEUROSCI 494: Research Independent Study 2 2021
- PHARM 393: Research Independent Study 2021
- PHARM 394: Research Independent Study 2021
- PHARM 493: Research Independent Study 2021
- PHARM 494: Research Independent Study 2021
- ENVIRON 815: Focused Topics in Toxicology 2020
- ENVIRON 848S: Seminar in Toxicology 2020
- NEUROSCI 493: Research Independent Study 1 2020
- NEUROSCI 494: Research Independent Study 2 2020
- PHARM 393: Research Independent Study 2020
- PHARM 394: Research Independent Study 2020
- PHARM 493: Research Independent Study 2020
- PHARM 494: Research Independent Study 2020
- PHARM 815: Focused Topics in Toxicology 2020
- PHARM 848S: Seminar in Toxicology 2020
- PSY 494: Research Independent Study 2020
- Scholarly, Clinical, & Service Activities
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Outreach & Engaged Scholarship
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