Scholars@Duke
Maria Emilia Panzetta

Maria Emilia Panzetta

Research Associate, Senior
Molecular Genetics and Microbiology
emi.panzetta@duke.edu
4200 MSRB III, Box 3580, Durham, NC 27710
4200 MSRB III Box 3580, 3 Genome Court, Durham, NC 27710

Selected Publications

The Biology of Akkermansia.

Journal Article Annu Rev Microbiol · October 2025 Members of the genus Akkermansia are the only cultured representatives of Verrucomicrobiota within the gastrointestinal tract. Akkermansia muciniphila, the best-characterized representative of the genus, is a mucin-degrading specialist that has emerged as ... Full text Link to item Cite

Urban wastewater overflows as hotspots for dissemination of bacteria producing extended-spectrum β-lactamases and carbapenemases in the Suquía River, Argentina

Journal Article Frontiers in Microbiology · January 1, 2025 Antimicrobial resistance (AMR) is a critical global challenge, yet the role of environmental dissemination of antibiotic-resistant bacteria remains underexplored, particularly in developing regions. This study investigated urban wastewater overflows from p ... Full text Cite

The Scientific and Therapeutic Rationale for Off-Label Treatments in Amyotrophic Lateral Sclerosis.

Journal Article Ann Neurol · November 6, 2024 There are no dramatically effective pharmacological treatments for most patients with amyotrophic lateral sclerosis, a complex disease with multiple underlying mechanisms, such as neuroinflammation, oxidative stress, mitochondrial dysfunction, microbiome a ... Full text Link to item Cite

Mechanism of 2'-fucosyllactose degradation by human-associated Akkermansia.

Journal Article J Bacteriol · February 22, 2024 Among the first microorganisms to colonize the human gut of breastfed infants are bacteria capable of fermenting human milk oligosaccharides (HMOs). One of the most abundant HMOs, 2'-fucosyllactose (2'-FL), may specifically drive bacterial colonization of ... Full text Link to item Cite

Pangenomic analysis identifies correlations between Akkermansia species and subspecies and human health outcomes.

Journal Article Microbiome Res Rep · 2024 Aim: Akkermansia are common members of the human gastrointestinal microbiota. The prevalence of these mucophilic bacteria, especially Akkermansia muciniphila (A. muciniphila), correlates with immunological and metabolic health. The genus Akkermansia in hum ... Full text Link to item Cite

Akkermansia in the gastrointestinal tract as a modifier of human health.

Journal Article Gut Microbes · 2024 Akkermansia sp are common members of the human gut microbiota. Multiple reports have emerged linking the abundance of A. muciniphila to health benefits and disease risk in humans and animals. This review highlights findings linking Akkermansia species in t ... Full text Link to item Cite

Ptr/CTL0175 Is Required for the Efficient Recovery of Chlamydia trachomatis From Stress Induced by Gamma-Interferon.

Journal Article Front Microbiol · 2019 Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen in humans and a frequent cause of asymptomatic, persistent infections leading to serious complications, particularly in young women. Chlamydia displays a unique obligate intra ... Full text Link to item Cite

Chlamydia Persistence: A Survival Strategy to Evade Antimicrobial Effects in-vitro and in-vivo.

Journal Article Front Microbiol · 2018 The Chlamydiaceae comprise a group of highly adapted bacterial pathogens sharing a unique intracellular lifestyle. Three Chlamydia species are pathogenic to humans: Chlamydia trachomatis, Chlamydia pneumoniae, and Chlamydia psittaci. C. trachomatis is the ... Full text Link to item Cite