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John E Jelovsek

F. Bayard Carter Distinguished Professor of Obstetrics and Gynecology
Obstetrics and Gynecology, Urogynecology
1200 Navaho Dr., Raleigh, NC 27609-7443
1200 Navaho Dr., Raleigh, NC 27609-7443

Overview


Dr. Jelovsek is the F. Bayard Carter Distinguished Professor of OBGYN at Duke University and serves as Director of Data Science for Women’s Health. He is Board Certified in OBGYN by the American Board of OBGYN and in Female Pelvic Medicine & Reconstructive Surgery by the American Board of OBGYN and American Board of Urology. He has an active surgical practice in urogynecology based out of Duke Raleigh. He has expertise as a clinician-scientist in developing and evaluating clinical prediction models using traditional biostatistics and machine learning approaches. These “individualized” patient-centered prediction tools aim to improve decision-making regarding the prevention of lower urinary tract symptoms (LUTS) and other pelvic floor disorders after childbirth (PMID:29056536), de novo stress urinary incontinence and other patient-perceived outcomes after pelvic organ prolapse surgery, risk of transfusion during gynecologic surgery, and urinary outcomes after mid-urethral sling surgery (PMID: 26942362). He also has significant expertise in leading trans-disciplinary teams through NIH-funded multi-center research networks and international settings. As alternate-PI for the Cleveland Clinic site in the NICHD Pelvic Floor Disorders Network, he was principal investigator on the CAPABLe trial (PMID: 31320277), one of the largest multi-center trials for fecal incontinence studying anal exercises with biofeedback and loperamide for the treatment of fecal incontinence. He was the principal investigator of the E-OPTIMAL study (PMID: 29677302), describing the long-term follow up sacrospinous ligament fixation compared to uterosacral ligament suspension for apical vaginal prolapse. He was also primary author on research establishing the minimum important clinical difference for commonly used measures of fecal incontinence. Currently, he serves as co-PI in the NIDDK Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) (U01DK097780-05) where he has been involved in studies in the development of Symptoms of Lower Urinary Tract Dysfunction Research Network Symptom Index-29 (LURN SI-29) and LURN SI-10 questionnaires for men and women with LUTS. He is also the site-PI for the PREMIER trial (1R01HD105892): Patient-Centered Outcomes of Sacrocolpopexy versus Uterosacral Ligament Suspension for the Treatment of Uterovaginal Prolapse.

Current Appointments & Affiliations


F. Bayard Carter Distinguished Professor of Obstetrics and Gynecology · 2023 - Present Obstetrics and Gynecology, Urogynecology, Obstetrics and Gynecology
Professor of Obstetrics and Gynecology · 2021 - Present Obstetrics and Gynecology, Urogynecology, Obstetrics and Gynecology

In the News


Published May 4, 2023
Duke Awards 44 Distinguished Professorships
Published April 17, 2018
Though Most Prolapse Pelvic Surgeries Regress Over Time, Symptoms Remain Improved
Published November 2, 2017
DCRI and International Investigators Develop Models to Predict Pelvic Floor Disorders

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Recent Publications


Validation and Recalibration of a Model for Predicting Surgical-Site Infection After Pelvic Organ Prolapse Surgery.

Journal Article Int Urogynecol J · February 2025 INTRODUCTION AND HYPOTHESIS: The objective was to externally validate and recalibrate a previously developed model for predicting postoperative surgical-site infection (SSI) after pelvic organ prolapse (POP) surgery. METHODS: This study utilized a previous ... Full text Link to item Cite

Correlation of Digital Rectal Examination and Anorectal Manometry with Patient-Reported Outcomes Among Women with Fecal Incontinence.

Journal Article Int Urogynecol J · December 2024 INTRODUCTION AND HYPOTHESIS: Standardized digital rectal examination (DRE) correlates with anorectal manometry (ARM) measures. However, less is known about the relationship between DRE/ARM measures and patient-reported outcomes (PROs), especially among wom ... Full text Link to item Cite

Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN): An introduction to the Urinary Urgency Phenotyping Protocol LURN II.

Journal Article Neurourol Urodyn · November 2024 AIMS: The Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) is undertaking a new cohort study in LURN II including cases and controls. METHODS: This new cohort was enrolled to specifically study urinary urgency and urgency urinary inconti ... Full text Link to item Cite
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Recent Grants


UrogynCREST Program

ResearchCo Investigator · Awarded by National Institutes of Health · 2019 - 2029

Duke KURe Program

Inst. Training Prgm or CMEMentor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2013 - 2028

Predicting phenotypes in benign urology

ResearchCo Investigator · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2027

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Education, Training & Certifications


Northwestern University · 2019 M.S.D.S.
University of Dundee (United Kingdom) · 2012 M.M.Ed.
East Tennessee State University, Quillen College of Medicine · 1999 M.D.