Scholars@Duke
Eric J Marrotte

Eric J Marrotte

Adjunct Associate in the Department of Neurology
Neurology, Neurocritical Care
eric.marrotte@duke.edu
DUMC Box 3824, Durham, NC 27710
Research Drive, Durham, NC 27110

Selected Publications

A Randomized, Placebo-Controlled, Phase II Trial of Intravenous Allogeneic Non-HLA Matched, Unrelated Donor, Cord Blood Infusion for Ischemic Stroke.

Journal Article Stem Cells Transl Med · February 14, 2024 Stroke remains a leading cause of death and disability in the US, and time-limited reperfusion strategies remain the only approved treatment options. To address this unmet clinical need, we conducted a phase II randomized clinical trial to determine whethe ... Full text Open Access Link to item Cite

Surgical Considerations to Improve Recovery in Acute Spinal Cord Injury.

Journal Article Neurospine · September 2022 Acute traumatic spinal cord injury (SCI) can be a devastating and costly event for individuals, their families, and the health system as a whole. Prognosis is heavily dependent on the physical extent of the injury and the severity of neurological dysfuncti ... Full text Link to item Cite

Effect of Acute Physical Interventions on Pathophysiology and Recovery After Spinal Cord Injury: A Comprehensive Review of the Literature.

Journal Article Neurospine · September 2022 Physical rehabilitation is essential for enhancing recovery in individuals with spinal cord injury (SCI); however, aside from early surgical intervention and hemodynamic management, there are no proven interventions for promoting recovery in the acute phas ... Full text Link to item Cite

Induction of Neurogenesis and Angiogenesis in a Rat Hemisection Spinal Cord Injury Model With Combined Neural Stem Cell, Endothelial Progenitor Cell, and Biomimetic Hydrogel Matrix Therapy.

Journal Article Crit Care Explor · June 2021 UNLABELLED: Acute spinal cord injury is a devastating injury that may lead to loss of independent function. Stem-cell therapies have shown promise; however, a clinically efficacious stem-cell therapy has yet to be developed. Functionally, endothelial proge ... Full text Link to item Cite

Spinal cord injury pharmacotherapy: Current research & development and competitive commercial landscape as of 2015.

Journal Article J Spinal Cord Med · January 2019 CONTEXT: Current treatment of spinal cord injury (SCI) focuses on cord stabilization to prevent further injury, rehabilitation, management of non-motor symptoms, and prevention of complications. Currently, no approved treatments are available, and limited ... Full text Link to item Cite

Neurocognitive outcomes after extracorporeal membrane oxygenation.

Journal Article Best Pract Res Clin Anaesthesiol · June 2015 Extracorporeal membrane oxygenation (ECMO) has been a therapy of last resort for the treatment of severe cardiorespiratory failure since the 1970s [1]. In recent years, ECMO has seen a resurgence in its use in adults. Recent work examining rates of ECMO us ... Full text Link to item Cite

Manganese superoxide dismutase expression in endothelial progenitor cells accelerates wound healing in diabetic mice.

Journal Article J Clin Invest · December 2010 Amputation as a result of impaired wound healing is a serious complication of diabetes. Inadequate angiogenesis contributes to poor wound healing in diabetic patients. Endothelial progenitor cells (EPCs) normally augment angiogenesis and wound repair but a ... Full text Link to item Cite