Overview
Former Chief Data Officer for Quality, Duke Health
Former Director of Duke Forge
Former Director of Duke Crucible
Former Assistant Dean for Biomedical Informatics
Dr. Huang is currently Associate Chief Clinical Officer for Informatics & Technology at Verily (Google's life sciences subsidiary), and is now adjunct faculty at Duke. Dr. Huang’s research interests span applied machine learning, research provenance and data infrastructure. Projects include building data provenance tools funded by the NIH’s Big Data to Knowledge program, regulatory science funded by the Burroughs Wellcome Foundation. Applied machine learning applications include “Deep Care Management” a highly interdisciplinary project with Duke Connected Care, Duke’s Accountable Care Organization, that integrates claims and EHR data for predicting unplanned admissions and risk stratifying patients for case management; CALYPSO, a collaboration with the Department of Surgery for utilizing machine learning to predict surgical complications. My team is also building the data platform for the Department of Surgery's "1000 Patients Project" an intensive biospecimen and biomarker study based around patients undergoing the controlled injury of surgery.
As Director of Duke Forge, Dr. Huang built a data science culture and infrastructure across Duke University that focused on actionable health data science. The Forge emphasized scientific rigor, awareness that technology does not supersede clinicians’ responsibilities and human relationship with their patients, and the role of data science in society.
Current Duke Appointments & Affiliations
Recent Scholarly Works
Improving representativeness in trial recruitment: A data-driven approach
Journal article Contemporary Clinical Trials Communications · June 1, 2026 Persistent under-representation of certain racial, ethnic, or socio-demographic subgroups in clinical studies continues to put patients at risk for unfavorable health outcomes. In an environment where accrual increasingly relies on digital campaigns, we pr ... Full text CiteNew Approach to Equitable Intervention Planning to Improve Engagement and Outcomes in a Digital Health Program: Simulation Study.
Journal article JMIR Diabetes · March 15, 2024 BACKGROUND: Digital health programs provide individualized support to patients with chronic diseases and their effectiveness is measured by the extent to which patients achieve target individual clinical outcomes and the program's ability to sustain patien ... Full text Open Access Link to item CiteIdentifying a stable and generalizable factor structure of major depressive disorder across three large longitudinal cohorts.
Journal article Psychiatry Res · March 2024 The Patient Health Questionnaire 9 (PHQ-9) is the current standard outpatient screening tool for measuring and tracking the nine symptoms of major depressive disorder (MDD). While the PHQ-9 was originally conceptualized as a unidimensional measure, it has ... Full text Open Access Link to item CiteRecent Grants
Bridging the Gap to Enhance Clinical Research Program (BIGGER)
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2016 - 2023Postdoctoral Training in Genomic Medicine Research
Inst. Training Prgm or CMECo-Mentor · Awarded by National Institutes of Health · 2017 - 2023Duke RDS2 (Respondent-Driven Sampling, Respiratory Disease Surveillance) the SNOWBALL Sampling Study
ResearchCo Investigator · Awarded by Centers for Disease Control and Prevention · 2020 - 2022View All Grants