Current Appointments & Affiliations
Assistant Professor in Dermatology
·
2021 - Present
Dermatology,
Clinical Science Departments
Recent Publications
DGAT1 Inhibition Induces Ferroptosis and Enhances Cancer Immunotherapy Efficacy.
Journal Article Cancer Res · March 11, 2026 Ferroptosis, a form of regulated cell death driven by lipid peroxidation, has emerged as a promising mechanism in cancer therapy. However, the lack of clinically viable ferroptosis inducers has precluded its therapeutic evaluation in patients. Here, we dem ... Full text Link to item CiteA noncanonical cytoplasmic role for BUB1 in restraining DNA damage-induced dsRNA accumulation and sensing within stress granules.
Journal Article Sci Immunol · August 8, 2025 Budding uninhibited by benzimidazoles 1 (BUB1) is a nuclear serine/threonine protein kinase that ensures proper chromosome segregation before mitosis. We report that BUB1 plays an unexpected cytoplasmic role in restraining DNA damage-induced accumulation o ... Full text Link to item CiteTargeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma.
Journal Article Cancer Res · November 4, 2024 Radiotherapy (RT) is commonly used to try to eliminate any remaining tumor cells following surgical resection of glioma. However, tumor recurrence is prevalent, highlighting the unmet medical need to develop therapeutic strategies to enhance the efficacy o ... Full text Link to item CiteRecent Grants
Novel roles of PCSK9 in regulating the tumor immune microenvironment during radiotherapy
ResearchCo-Principal Investigator · Awarded by National Cancer Institute · 2022 - 2027Targeting ATM to boost systemic effects of radiotherapy and immunotherapy
ResearchCo-Principal Investigator · Awarded by National Cancer Institute · 2021 - 2026Necroptotic genes in cancer cellular response to radiation
ResearchCo Investigator · Awarded by National Institutes of Health · 2017 - 2024View All Grants
Education
Sun Yat Sen University (China) ·
2001
Ph.D.
Sichuan University (China) ·
1987
B.S.