Herbert Edgar Fuchs
Professor of Neurosurgery
Clinical neuro-oncology research including collaborations studying molecular genetics of childhood brain tumors.
Potential role of the free electron laser in surgery of pediatric brain tumors. Current work includes animal models with human brain tumor xenografts in preclinical studies.
Collaboration with the neurooncology laboratory of Dr. Darell Bigner in preclinical studies of new therapeutic agents.
Potential role of the free electron laser in surgery of pediatric brain tumors. Current work includes animal models with human brain tumor xenografts in preclinical studies.
Collaboration with the neurooncology laboratory of Dr. Darell Bigner in preclinical studies of new therapeutic agents.
Current Appointments & Affiliations
- Professor of Neurosurgery, Neurosurgery, Neurosurgery 2017
- Professor of Pediatrics, Pediatrics, Clinical Science Departments 2017
- Assistant Professor of Pathology, Pathology, Clinical Science Departments 2017
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1992
Contact Information
- 4544 Hospital South, Box 3807, Durham, NC 27710
- Box 3807, Durham, NC 27710
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fuchs001@mc.duke.edu
(919) 681-0894
- Background
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Education, Training, & Certifications
- M.D., Duke University 1984
- Ph.D., Duke University 1984
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Previous Appointments & Affiliations
- Assistant Professor of Pediatrics, Pediatrics, Clinical Science Departments 2017 - 2018
- Assistant Professor of Pediatrics, Pediatrics, Clinical Science Departments 1995 - 2017
- Associate Professor of Neurosurgery, Neurosurgery, Neurosurgery 2002 - 2017
- Assistant Professor of Pathology, Pathology, Clinical Science Departments 1995 - 2016
- Associate Professor of Surgery, Neurosurgery, Neurosurgery 1996 - 2002
- Assistant Professor of Pediatric Neurosurgery in the Department of Surgery, Neurosurgery, Neurosurgery 1993 - 1996
- Research
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Selected Grants
- Research Training In Neuro-Oncology awarded by National Institutes of Health 1998 - 2016
- Linkage and candidate gene analysis in non-syndromic Chiari type I awarded by National Institutes of Health 2009 - 2015
- Research Training In Neuro-Oncology awarded by National Institutes of Health 2005 - 2010
- Src On Primary And Matastatic Tumors Of The Cns awarded by National Institutes of Health 1994 - 1999
- Src On Primary And Metastatic Tumors Of The Cns awarded by National Institutes of Health 1997 - 1999
- Src On Malignant Human Gliomas And Medulloblastomas awarded by National Institutes of Health 1993 - 1994
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External Relationships
- North Carolina Physicians Advisory Group
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Suarez, Alexander D., Brad Taicher, Herbert Fuchs, Jeffery Marcus, Matthew Vestal, Mayumi Homi, Alexander Allori, and Eric M. Thompson. “Predictors of Blood Transfusion for Endoscopic Assisted Craniosynostosis Surgery.” J Craniofac Surg 33, no. 5 (July 2022): 1327–30. https://doi.org/10.1097/SCS.0000000000008441.Full Text Link to Item
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Akbari, S Hassan A., Alexander T. Yahanda, Laurie L. Ackerman, P David Adelson, Raheel Ahmed, Gregory W. Albert, Philipp R. Aldana, et al. “Complications and outcomes of posterior fossa decompression with duraplasty versus without duraplasty for pediatric patients with Chiari malformation type I and syringomyelia: a study from the Park-Reeves Syringomyelia Research Consortium.” J Neurosurg Pediatr, April 15, 2022, 1–13. https://doi.org/10.3171/2022.2.PEDS21446.Full Text Link to Item
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Akbari, Syed Hassan A., Asad A. Rizvi, Travis S. CreveCoeur, Rowland H. Han, Jacob K. Greenberg, James Torner, Douglas L. Brockmeyer, et al. “Socioeconomic and demographic factors in the diagnosis and treatment of Chiari malformation type I and syringomyelia.” J Neurosurg Pediatr, December 3, 2021, 1–10. https://doi.org/10.3171/2021.9.PEDS2185.Full Text Link to Item
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Hendrix, Grace, Robert Benjamin, Nancie MacIver, Daniel P. Barboriak, Herbert Fuchs, and Pinar Gumus Balikcioglu. “Pediatric Giant Prolactinoma Presenting With Acute Obstructive Hydrocephalus and Intracranial Hypertension.” J Endocr Soc 5, no. 12 (December 1, 2021): bvab160. https://doi.org/10.1210/jendso/bvab160.Full Text Link to Item
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Park, Christine, Beiyu Liu, Stephen C. Harward, Anru R. Zhang, Jared Gloria, Hui-Jie Lee, Herbert E. Fuchs, Carrie R. Muh, Sarah E. Hodges, and Eric M. Thompson. “Ventriculomegaly and postoperative lateral/third ventricular blood as predictors of cerebrospinal fluid diversion following posterior fossa tumor resection.” J Neurosurg Pediatr 28, no. 5 (August 13, 2021): 533–43. https://doi.org/10.3171/2021.4.PEDS2188.Full Text Link to Item
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Sadler, Brooke, Alex Skidmore, Jordan Gewirtz, Richard C. E. Anderson, Gabe Haller, Laurie L. Ackerman, P David Adelson, et al. “Extradural decompression versus duraplasty in Chiari malformation type I with syrinx: outcomes on scoliosis from the Park-Reeves Syringomyelia Research Consortium.” J Neurosurg Pediatr, June 18, 2021, 1–9. https://doi.org/10.3171/2020.12.PEDS20552.Full Text Link to Item
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CreveCoeur, Travis S., Alexander T. Yahanda, Cormac O. Maher, Gabrielle W. Johnson, Laurie L. Ackerman, P David Adelson, Raheel Ahmed, et al. “Occipital-Cervical Fusion and Ventral Decompression in the Surgical Management of Chiari-1 Malformation and Syringomyelia: Analysis of Data From the Park-Reeves Syringomyelia Research Consortium.” Neurosurgery 88, no. 2 (January 13, 2021): 332–41. https://doi.org/10.1093/neuros/nyaa460.Full Text Link to Item
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Monuszko, Karen, Michael Malinzak, Lexie Zidanyue Yang, Donna Niedzwiecki, Herbert Fuchs, Carrie R. Muh, Krista Gingrich, Robert Lark, and Eric M. Thompson. “Image quality of EOS low-dose radiography in comparison with conventional radiography for assessment of ventriculoperitoneal shunt integrity.” J Neurosurg Pediatr 27, no. 4 (January 8, 2021): 375–81. https://doi.org/10.3171/2020.8.PEDS20428.Full Text Link to Item
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Muh, Carrie R., Naomi D. Chou, Shervin Rahimpour, Jordan M. Komisarow, Tracy G. Spears, Herbert E. Fuchs, Sandra Serafini, and Gerald A. Grant. “Cortical stimulation mapping for localization of visual and auditory language in pediatric epilepsy patients.” J Neurosurg Pediatr, November 8, 2019, 1–10. https://doi.org/10.3171/2019.8.PEDS1922.Full Text Open Access Copy Link to Item
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Strahle, Jennifer M., Rukayat Taiwo, Christine Averill, James Torner, Chevis N. Shannon, Christopher M. Bonfield, Gerald F. Tuite, et al. “Radiological and clinical predictors of scoliosis in patients with Chiari malformation type I and spinal cord syrinx from the Park-Reeves Syringomyelia Research Consortium.” J Neurosurg Pediatr, August 16, 2019, 1–8. https://doi.org/10.3171/2019.5.PEDS18527.Full Text Link to Item
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Gupta, Nalin, Liliana C. Goumnerova, Peter Manley, Susan N. Chi, Donna Neuberg, Maneka Puligandla, Jason Fangusaro, et al. “Prospective feasibility and safety assessment of surgical biopsy for patients with newly diagnosed diffuse intrinsic pontine glioma.” Neuro Oncol 20, no. 11 (October 9, 2018): 1547–55. https://doi.org/10.1093/neuonc/noy070.Full Text Link to Item
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Sergesketter, Amanda R., Aladine A. Elsamadicy, David T. Lubkin, Hanna Kemeny, Stephen C. Harward, Kate B. Krucoff, Max O. Krucoff, et al. “Socioeconomic Factors, Perioperative Complications, and 30-Day Readmission Rates Associated With Delayed Cranial Vault Reconstruction for Craniosynostosis.” J Craniofac Surg 29, no. 7 (October 2018): 1767–71. https://doi.org/10.1097/SCS.0000000000004787.Full Text Link to Item
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Tan, Char-Loo, Daniel Landi, Herbert Fuchs, and Roger E. McLendon. “Novel case of recurrent intraventricular atypical central neurocytoma with prominent gangliogliomatous differentiation in a 10-year-old boy with 10 years of follow up.” Neuropathology 38, no. 5 (October 2018): 542–48. https://doi.org/10.1111/neup.12502.Full Text Link to Item
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Narine, Kalindi Y., Christopher C. Oh, Herbert E. Fuchs, and David Van Mater. “Calvarial mass as a presenting feature of neurofibromatosis type 2 in a pediatric patient.” Am J Med Genet A 176, no. 1 (January 2018): 246–47. https://doi.org/10.1002/ajmg.a.38505.Full Text Link to Item
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Dai, Rui, Irene J. Pien, David A. Brown, Andre Marshall, Herbert E. Fuchs, and Jeffrey R. Marcus. “Multiple Recurrent Fibromatosis With Cranial Fasciitis Characteristics in a Pediatric Patient.” J Craniofac Surg 28, no. 7 (October 2017): 1821–23. https://doi.org/10.1097/SCS.0000000000003860.Full Text Link to Item
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Jiramongkolchai, Kim, Muhammed T. Bhatti, Herbert E. Fuchs, Thomas E. Cummings, Pawina Jiramongkolchai, and Mays A. El-Dairi. “Endodermal Cyst of the Third Nerve in a Child.” J Neuroophthalmol 37, no. 3 (September 2017): 311–13. https://doi.org/10.1097/WNO.0000000000000443.Full Text Link to Item
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McKinnon, Elizabeth L., Andrew J. Rand, M Angelica Selim, Herbert E. Fuchs, Anne F. Buckley, and Thomas J. Cummings. “Rhabdomyomatous mesenchymal hamartoma presenting as a sacral skin tag in two neonates with spinal dysraphism.” J Cutan Pathol 42, no. 10 (October 2015): 774–78. https://doi.org/10.1111/cup.12538.Full Text Link to Item
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Nair, Smita K., Timothy Driscoll, David Boczkowski, Robert Schmittling, Renee Reynolds, Laura A. Johnson, Gerald Grant, et al. “Ex vivo generation of dendritic cells from cryopreserved, post-induction chemotherapy, mobilized leukapheresis from pediatric patients with medulloblastoma.” J Neurooncol 125, no. 1 (October 2015): 65–74. https://doi.org/10.1007/s11060-015-1890-2.Full Text Link to Item
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McLendon, Roger E., Eric Lipp, Diane Satterfield, Melissa Ehinger, Alan Austin, Debra Fleming, Kathryn Perkinson, et al. “Prognostic marker analysis in pediatric intracranial ependymomas.” J Neurooncol 122, no. 2 (April 2015): 255–61. https://doi.org/10.1007/s11060-014-1711-z.Full Text Link to Item
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Lock, Eric F., Karen L. Soldano, Melanie E. Garrett, Heidi Cope, Christina A. Markunas, Herbert Fuchs, Gerald Grant, David B. Dunson, Simon G. Gregory, and Allison E. Ashley-Koch. “Joint eQTL assessment of whole blood and dura mater tissue from individuals with Chiari type I malformation.” Bmc Genomics 16, no. 1 (January 22, 2015): 11. https://doi.org/10.1186/s12864-014-1211-8.Full Text Open Access Copy Link to Item
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Markunas, Christina A., Eric Lock, Karen Soldano, Heidi Cope, Chien-Kuang C. Ding, David S. Enterline, Gerald Grant, Herbert Fuchs, Allison E. Ashley-Koch, and Simon G. Gregory. “Identification of Chiari Type I Malformation subtypes using whole genome expression profiles and cranial base morphometrics.” Bmc Med Genomics 7 (June 25, 2014): 39. https://doi.org/10.1186/1755-8794-7-39.Full Text Open Access Copy Link to Item
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López, G. Y., G. A. Grant, H. E. Fuchs, L. G. Leithe, S. Gururangan, D. D. Bigner, H. Yan, R. E. McLendon, and Y. He. “Clinico-pathological description of three paediatric medulloblastoma cases with MLL2/3 gene mutations.” Neuropathol Appl Neurobiol 40, no. 2 (February 2014): 217–20. https://doi.org/10.1111/nan.12060.Full Text Link to Item
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Markunas, Christina A., David S. Enterline, Kaitlyn Dunlap, Karen Soldano, Heidi Cope, Jeffrey Stajich, Gerald Grant, Herbert Fuchs, Simon G. Gregory, and Allison E. Ashley-Koch. “Genetic evaluation and application of posterior cranial fossa traits as endophenotypes for Chiari type I malformation.” Ann Hum Genet 78, no. 1 (January 2014): 1–12. https://doi.org/10.1111/ahg.12041.Full Text Link to Item
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Markunas, Christina A., Karen Soldano, Kaitlyn Dunlap, Heidi Cope, Edgar Asiimwe, Jeffrey Stajich, David Enterline, et al. “Stratified whole genome linkage analysis of Chiari type I malformation implicates known Klippel-Feil syndrome genes as putative disease candidates.” Plos One 8, no. 4 (2013): e61521. https://doi.org/10.1371/journal.pone.0061521.Full Text Open Access Copy Link to Item
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Choi, Bryan D., Tiffany R. Hodges, Gerald A. Grant, Herbert E. Fuchs, Thomas J. Cummings, and Carrie R. Muh. “Inflammatory pseudotumor of the lateral ventricle in a pediatric patient.” Pediatr Neurosurg 48, no. 6 (2012): 374–78. https://doi.org/10.1159/000353609.Full Text Link to Item
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Parker, Stephen R., Peggy Harris, Thomas J. Cummings, Timothy George, Herbert Fuchs, and Gerald Grant. “Complications following decompression of Chiari malformation Type I in children: dural graft or sealant?” J Neurosurg Pediatr 8, no. 2 (August 2011): 177–83. https://doi.org/10.3171/2011.5.PEDS10362.Full Text Link to Item
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Stack, A., S. L. Peterson-Carmichael, D. E. Yin, M. L. Marti, H. Fuchs, R. Jhaveri, and D. A. Turner. “CA-MRSA brain abscess in a healthy infant.” Journal of Pediatric Infectious Diseases 6, no. 1 (April 25, 2011): 71–75. https://doi.org/10.3233/JPI-2011-0290.Full Text
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Aliabadi, Hamidreza, Renee Reynolds, Ciaran J. Powers, Gerald Grant, Herbert Fuchs, and Joanne Kurtzberg. “Clinical outcome of cerebrospinal fluid shunting for communicating hydrocephalus in mucopolysaccharidoses I, II, and III: a retrospective analysis of 13 patients.” Neurosurgery 67, no. 6 (December 2010): 1476–81. https://doi.org/10.1227/NEU.0b013e3181f8c11d.Full Text Open Access Copy Link to Item
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Karikari, Isaac O., Gerald Grant, Thomas J. Cummings, Jeffrey Petrella, and Herbert E. Fuchs. “Endodermal cyst of the oculomotor nerve.” Pediatr Neurosurg 46, no. 2 (August 2010): 155–56. https://doi.org/10.1159/000319562.Full Text Link to Item
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Nimjee, Shahid M., Ciaran J. Powers, Roger E. McLendon, Gerald A. Grant, and Herbert E. Fuchs. “Single-stage bilateral choroid plexectomy for choroid plexus papilloma in a patient presenting with high cerebrospinal fluid output.” J Neurosurg Pediatr 5, no. 4 (April 2010): 342–45. https://doi.org/10.3171/2009.10.PEDS08454.Full Text Link to Item
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Hughes, Betsy D., Gerald A. Grant, Thomas J. Cummings, and Herbert E. Fuchs. “Disappearing bone disease and Chiari I malformation.” Pediatr Neurosurg 46, no. 1 (2010): 58–61. https://doi.org/10.1159/000315005.Full Text Link to Item
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Aliabadi, H., J. Miller, S. Radnakrishnan, A. I. Mehta, K. Thomas, L. Selznick, R. Goldberg, G. Grant, and H. Fuchs. “Spontaneous intrauterine "ping-pong" fracture: review and case illustration.” Neuropediatrics 40, no. 2 (April 2009): 73–75. https://doi.org/10.1055/s-0029-1234108.Full Text Link to Item
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Waldau, Ben, Leahthan F. Domeshek, Fawn A. Leigh, Kristian C. Lum, Herbert E. Fuchs, Jeffrey R. Marcus, Srinivasan Mukundan, and Gerald A. Grant. “Spontaneous resolution of a 13-mm Chiari malformation Type I in relation to differential growth of the posterior fossa volume.” J Neurosurg Pediatr 3, no. 2 (February 2009): 110–14. https://doi.org/10.3171/2008.10.PEDS08200.Full Text Link to Item
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Waldau, Ben, Roger E. McLendon, Herbert E. Fuchs, Timothy M. George, and Gerald A. Grant. “Few isolated neurons in hypothalamic hamartomas may cause gelastic seizures.” Pediatr Neurosurg 45, no. 3 (2009): 225–29. https://doi.org/10.1159/000224620.Full Text Link to Item
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Gururangan, Sridharan, Jeanne Krauser, Melody A. Watral, Tim Driscoll, Nicole Larrier, David A. Reardon, Jeremy N. Rich, et al. “Efficacy of high-dose chemotherapy or standard salvage therapy in patients with recurrent medulloblastoma.” Neuro Oncol 10, no. 5 (October 2008): 745–51. https://doi.org/10.1215/15228517-2008-044.Full Text Link to Item
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Inman, Page C., Srinivasan Mukundan, Herbert E. Fuchs, and Jeffrey R. Marcus. “Craniosynostosis and rickets.” Plast Reconstr Surg 121, no. 4 (April 2008): 217e-218e. https://doi.org/10.1097/01.prs.0000305381.61117.2f.Full Text Link to Item
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Waldau, Ben, Gerald Grant, and Herbert Fuchs. “Development of an acquired Chiari malformation Type I in the setting of an untreated lipomyelomeningocele. Case report.” J Neurosurg Pediatr 1, no. 2 (February 2008): 164–66. https://doi.org/10.3171/PED/2008/1/2/164.Full Text Link to Item
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Mukundan, Srinivasan, Herbert Fuchs, Michael J. Alexander, and Gerald A. Grant. “Dynamic contrast-enhanced magnetic resonance angiography of vascular malformations in pediatric patients. Case report.” J Neurosurg 107, no. 3 Suppl (September 2007): 228–31. https://doi.org/10.3171/PED-07/09/228.Full Text Link to Item
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Rajpal, Sharad, R Shane Tubbs, Timothy George, W Jerry Oakes, Herbert E. Fuchs, Mark N. Hadley, and Bermans J. Iskandar. “Tethered cord due to spina bifida occulta presenting in adulthood: a tricenter review of 61 patients.” J Neurosurg Spine 6, no. 3 (March 2007): 210–15. https://doi.org/10.3171/spi.2007.6.3.210.Full Text Link to Item
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Powers, Ciaran J., Herbert E. Fuchs, and Timothy M. George. “Chronic subdural hematoma of the neonate: report of two cases and literature review.” Pediatr Neurosurg 43, no. 1 (2007): 25–28. https://doi.org/10.1159/000097521.Full Text Link to Item
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Wang, P. I., J. R. Marcus, H. E. Fuchs, and S. Mukundan. “Craniosynostosis Secondary to Rickets: Manifestations on Computed Tomography.” Radiology Case Reports 2, no. 3 (January 1, 2007): 43. https://doi.org/10.2484/rcr.v2i3.43.Full Text
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Powers, Ciaran J., Kent C. New, Roger E. McLendon, Allan H. Friedman, and Herbert E. Fuchs. “Cerebellopontine angle craniopharyngioma: case report and literature review.” Pediatr Neurosurg 43, no. 2 (2007): 158–63. https://doi.org/10.1159/000098394.Full Text Link to Item
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Powers, Ciaran J., Timothy George, and Herbert E. Fuchs. “Constipation as a reversible cause of ventriculoperitoneal shunt failure. Report of two cases.” J Neurosurg 105, no. 3 Suppl (September 2006): 227–30. https://doi.org/10.3171/ped.2006.105.3.227.Full Text Link to Item
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McGirt, Matthew J., Shahid M. Nimjee, Herbert E. Fuchs, and Timothy M. George. “Relationship of cine phase-contrast magnetic resonance imaging with outcome after decompression for Chiari I malformations.” Neurosurgery 59, no. 1 (July 2006): 140–46. https://doi.org/10.1227/01.NEU.0000219841.73999.B3.Full Text Link to Item
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Mazur, Melissa A., Sridharan Gururangan, Julia A. Bridge, Thomas J. Cummings, Srinivasan Mukundan, Herbert Fuchs, Nicole Larrier, and Edward C. Halperin. “Intracranial Ewing sarcoma.” Pediatr Blood Cancer 45, no. 6 (November 2005): 850–56. https://doi.org/10.1002/pbc.20430.Full Text Link to Item
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O’Connell, Martin, Terence Z. Wong, Kevin E. Forkheim, Manoj Jain, Stephen W. Shipes, and Herbert E. Fuchs. “Comparison of Tc99m-DTPA and indium-111 DTPA studies of baclofen pump function.” Clin Nucl Med 29, no. 9 (September 2004): 578–80. https://doi.org/10.1097/01.rlu.0000134995.55131.30.Full Text Link to Item
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Cummings, T. J., T. M. George, H. E. Fuchs, and R. E. McLendon. “The pathology of extracranial scalp and skull masses in young children.” Clin Neuropathol 23, no. 1 (2004): 34–43.Link to Item
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Gururangan, Sridharan, Colleen McLaughlin, Jennifer Quinn, Jeremy Rich, David Reardon, Edward C. Halperin, James Herndon, et al. “High-dose chemotherapy with autologous stem-cell rescue in children and adults with newly diagnosed pineoblastomas.” J Clin Oncol 21, no. 11 (June 1, 2003): 2187–91. https://doi.org/10.1200/JCO.2003.10.096.Full Text Link to Item
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Villavicencio, Alan T., Jean-Christophe Leveque, Matthew J. McGirt, John S. Hopkins, Herbert E. Fuchs, and Timothy M. George. “Comparison of revision rates following endoscopically versus nonendoscopically placed ventricular shunt catheters.” Surg Neurol 59, no. 5 (May 2003): 375–79. https://doi.org/10.1016/s0090-3019(03)00070-3.Full Text Link to Item
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McGirt, Matthew J., Aimee Zaas, Herbert E. Fuchs, Timothy M. George, Keith Kaye, and Daniel J. Sexton. “Risk factors for pediatric ventriculoperitoneal shunt infection and predictors of infectious pathogens.” Clin Infect Dis 36, no. 7 (April 1, 2003): 858–62. https://doi.org/10.1086/368191.Full Text Link to Item
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McGirt, Matthew J., John C. Wellons, Shahid M. Nimjee, Ketan R. Bulsara, Herbert E. Fuchs, and Timothy M. George. “Comparison of total versus partial revision of initial ventriculoperitoneal shunt failures.” Pediatr Neurosurg 38, no. 1 (January 2003): 34–40. https://doi.org/10.1159/000067561.Full Text Link to Item
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McGirt, Matthew J., Jean-Christophe Leveque, John C. Wellons, Alan T. Villavicencio, John S. Hopkins, Herbert E. Fuchs, and Timoth M. George. “Cerebrospinal fluid shunt survival and etiology of failures: a seven-year institutional experience.” Pediatr Neurosurg 36, no. 5 (May 2002): 248–55. https://doi.org/10.1159/000058428.Full Text Link to Item
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Bulsara, K. R., A. R. Zomorodi, A. T. Villavicencio, H. Fuchs, and T. M. George. “Clinical outcome differences for lipomyelomeningoceles, intraspinal lipomas, and lipomas of the filum terminale.” Neurosurg Rev 24, no. 4 (December 2001): 192–94. https://doi.org/10.1007/s101430100177.Full Text Link to Item
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Worley, G., J. S. Wiener, T. M. George, H. E. Fuchs, J. F. Mackey, R. D. Fitch, and K. T. Oldham. “Acute abdominal symptoms and signs in children and young adults with spina bifida: ten years' experience.” J Pediatr Surg 36, no. 9 (September 2001): 1381–86. https://doi.org/10.1053/jpsu.2001.26375.Full Text Link to Item
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McLendon, R. E., H. S. Friedman, H. E. Fuchs, L. E. Kun, and S. H. Bigner. “Diagnostic markers in paediatric medulloblastoma: a Paediatric Oncology Group Study.” Histopathology 34, no. 2 (February 1999): 154–62. https://doi.org/10.1046/j.1365-2559.1999.00577.x.Full Text Link to Item
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Archer, G. E., J. H. Sampson, R. E. McLendon, A. H. Friedman, O. M. Colvin, M. Rose, H. Sands, et al. “Intrathecal busulfan treatment of human neoplastic meningitis in athymic nude rats.” J Neurooncol 44, no. 3 (1999): 233–41. https://doi.org/10.1023/a:1006304424346.Full Text Link to Item
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Lee, S. E., S. P. Johnson, L. P. Hale, J. Li, N. Bullock, H. Fuchs, A. Friedman, et al. “Analysis of DNA mismatch repair proteins in human medulloblastoma.” Clin Cancer Res 4, no. 6 (June 1998): 1415–19.Link to Item
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Moghrabi, A., H. S. Friedman, D. M. Ashley, K. S. Bottom, T. Kerby, E. Stewart, C. Bruggers, et al. “Phase II study of carboplatin (CBDCA) in progressive low-grade gliomas.” Neurosurg Focus 4, no. 4 (April 15, 1998): e3. https://doi.org/10.3171/foc.1998.4.4.6.Full Text Link to Item
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McCowage, G. B., H. S. Friedman, A. Moghrabi, T. Kerby, L. Ferrell, E. Stewart, M. Duncan-Brown, et al. “Activity of high-dose cyclophosphamide in the treatment of childhood malignant gliomas.” Med Pediatr Oncol 30, no. 2 (February 1998): 75–80. https://doi.org/10.1002/(sici)1096-911x(199802)30:2<75::aid-mpo1>3.0.co;2-x.Full Text Link to Item
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Slavik, T., R. C. Bentley, L. Gray, H. E. Fuchs, and R. E. McLendon. “Solitary fibrous tumor of the meninges occurring after irradiation of a mixed germ cell tumor of the pineal gland.” Clin Neuropathol 17, no. 1 (1998): 55–60.Link to Item
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Sampson, J. H., D. M. Ashley, G. E. Archer, H. E. Fuchs, G. Dranoff, L. P. Hale, and D. D. Bigner. “Characterization of a spontaneous murine astrocytoma and abrogation of its tumorigenicity by cytokine secretion.” Neurosurgery 41, no. 6 (December 1997): 1365–72. https://doi.org/10.1097/00006123-199712000-00024.Full Text Link to Item
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Bigner, S. H., R. E. McLendon, H. Fuchs, P. E. McKeever, and H. S. Friedman. “Chromosomal characteristics of childhood brain tumors.” Cancer Genet Cytogenet 97, no. 2 (September 1997): 125–34. https://doi.org/10.1016/s0165-4608(96)00404-9.Full Text Link to Item
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Ashley, D. M., R. E. Coleman, H. Fuchs, G. Dear, B. Ginsberg, F. M. Zalduondo, H. S. Friedman, and D. Longee. “Chronic CSF leak into the peritoneal cavity shown by radionuclide cisternography. Successful treatment with an epidural blood patch.” Clin Nucl Med 22, no. 6 (June 1997): 390–92. https://doi.org/10.1097/00003072-199706000-00010.Full Text Link to Item
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Moghrabi, A., R. Tien, H. Fuchs, D. Longee, R. McLendon, and H. S. Friedman. “False positive images in the follow-up of patients with brain tumors.” Med Pediatr Oncol 28, no. 2 (February 1997): 127–31. https://doi.org/10.1002/(sici)1096-911x(199702)28:2<127::aid-mpo6>3.0.co;2-m.Full Text Link to Item
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Sampson, J. H., G. E. Archer, D. M. Ashley, H. E. Fuchs, L. P. Hale, G. Dranoff, and D. D. Bigner. “Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system.” Proc Natl Acad Sci U S A 93, no. 19 (September 17, 1996): 10399–404. https://doi.org/10.1073/pnas.93.19.10399.Full Text Link to Item
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McCowage, G., R. Tien, R. McLendon, G. Felsberg, H. Fuchs, M. L. Graham, J. Kurtzberg, et al. “Successful treatment of childhood pilocytic astrocytomas metastatic to the leptomeninges with high-dose cyclophosphamide.” Med Pediatr Oncol 27, no. 1 (July 1996): 32–39. https://doi.org/10.1002/(SICI)1096-911X(199607)27:1<32::AID-MPO7>3.0.CO;2-V.Full Text Link to Item
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Ashley, D. M., D. Longee, R. Tien, H. Fuchs, M. L. Graham, J. Kurtzberg, J. Casey, et al. “Treatment of patients with pineoblastoma with high dose cyclophosphamide.” Med Pediatr Oncol 26, no. 6 (June 1996): 387–92. https://doi.org/10.1002/(SICI)1096-911X(199606)26:6<387::AID-MPO3>3.0.CO;2-D.Full Text Link to Item
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Caress, J. B., V. Nohria, H. Fuchs, and R. M. Boustany. “Torticollis acquired in late infancy due to a cerebellar gangliocytoma.” Int J Pediatr Otorhinolaryngol 36, no. 1 (June 1996): 39–44. https://doi.org/10.1016/0165-5876(95)01320-2.Full Text Link to Item
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Blaeker, H., B. K. Rasheed, R. E. McLendon, H. S. Friedman, S. K. Batra, H. E. Fuchs, and S. H. Bigner. “Microsatellite analysis of childhood brain tumors.” Genes Chromosomes Cancer 15, no. 1 (January 1996): 54–63. https://doi.org/10.1002/(SICI)1098-2264(199601)15:1<54::AID-GCC8>3.0.CO;2-3.Full Text Link to Item
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Bigner, D. D., G. E. Archer, R. E. McLendon, H. S. Friedman, H. E. Fuchs, L. H. Pai, J. E. Herndon, and I. H. Pastan. “Efficacy of compartmental administration of immunotoxin LMB-1 (B3-LysPE38) in a rat model of carcinomatous meningitis.” Clin Cancer Res 1, no. 12 (December 1995): 1545–55.Link to Item
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Lirng, J. F., D. S. Enterline, R. D. Tien, H. Fuchs, H. S. Friedman, K. S. Ellington, and R. P. McLendon. “MRI of papillary meningiomas in children.” Pediatr Radiol 25 Suppl 1 (November 1995): S9-13.Link to Item
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Kurpad, S. N., H. S. Friedman, G. E. Archer, R. E. McLendon, W. M. Petros, H. E. Fuchs, A. Guaspari, and D. D. Bigner. “Intraarterial administration of melphalan for treatment of intracranial human glioma xenografts in athymic rats.” Cancer Res 55, no. 17 (September 1, 1995): 3803–9.Link to Item
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Moghrabi, A., H. Fuchs, M. Brown, S. C. Schold, M. Graham, J. Kurtzberg, R. Tien, G. Felsberg, D. H. Lachance, and O. M. Colvin. “Cyclophosphamide in combination with sargramostim for treatment of recurrent medulloblastoma.” Med Pediatr Oncol 25, no. 3 (September 1995): 190–96. https://doi.org/10.1002/mpo.2950250306.Full Text Link to Item
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Lachance, D. H., D. Oette, S. C. Schold, M. Brown, J. Kurtzberg, M. L. Graham, R. Tien, G. Felsberg, O. M. Colvin, and A. Moghrabi. “Dose escalation trial of cyclophosphamide with Sargramostim in the treatment of central nervous system (CNS) neoplasms.” Med Pediatr Oncol 24, no. 4 (April 1995): 241–47. https://doi.org/10.1002/mpo.2950240406.Full Text Link to Item
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Pastan, I. H., G. E. Archer, R. E. McLendon, H. S. Friedman, H. E. Fuchs, Q. C. Wang, L. H. Pai, J. Herndon, and D. D. Bigner. “Intrathecal administration of single-chain immunotoxin, LMB-7 [B3(Fv)-PE38], produces cures of carcinomatous meningitis in a rat model.” Proc Natl Acad Sci U S A 92, no. 7 (March 28, 1995): 2765–69. https://doi.org/10.1073/pnas.92.7.2765.Full Text Link to Item
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Fuchs, H. E., and D. G. McLone. “Diagnosis and management of astrocytomas occurring in the posterior fossa.” Neurosurgery Quarterly 5, no. 3 (January 1, 1995): 168–78. https://doi.org/10.1097/00013414-199509000-00002.Full Text
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Batra, S. K., R. E. McLendon, J. S. Koo, S. Castelino-Prabhu, H. E. Fuchs, J. P. Krischer, H. S. Friedman, D. D. Bigner, and S. H. Bigner. “Prognostic implications of chromosome 17p deletions in human medulloblastomas.” J Neurooncol 24, no. 1 (1995): 39–45. https://doi.org/10.1007/BF01052657.Full Text Link to Item
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Friedman, H. S., G. E. Archer, R. E. McLendon, J. M. Schuster, O. M. Colvin, A. Guaspari, R. Blum, P. A. Savina, H. E. Fuchs, and D. D. Bigner. “Intrathecal melphalan therapy of human neoplastic meningitis in athymic nude rats.” Cancer Res 54, no. 17 (September 1, 1994): 4710–14.Link to Item
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Halperin, E. C., H. S. Friedman, S. C. Schold, H. E. Fuchs, W. J. Oakes, B. Hockenberger, and P. C. Burger. “Surgery, hyperfractionated craniospinal irradiation, and adjuvant chemotherapy in the management of supratentorial embryonal neuroepithelial neoplasms in children.” Surg Neurol 40, no. 4 (October 1993): 278–83. https://doi.org/10.1016/0090-3019(93)90138-q.Full Text Link to Item
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Schuster, J. M., H. S. Friedman, G. E. Archer, H. E. Fuchs, R. E. McLendon, O. M. Colvin, and D. D. Bigner. “Intraarterial therapy of human glioma xenografts in athymic rats using 4-hydroperoxycyclophosphamide.” Cancer Res 53, no. 10 Suppl (May 15, 1993): 2338–43.Link to Item
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Fuchs, H. E., G. E. Archer, O. M. Colvin, S. H. Bigner, J. M. Schuster, G. N. Fuller, L. H. Muhlbaier, S. C. Schold, H. S. Friedman, and D. D. Bigner. “Activity of intrathecal 4-hydroperoxycyclophosphamide in a nude rat model of human neoplastic meningitis.” Cancer Res 50, no. 6 (March 15, 1990): 1954–59.Link to Item
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Fuchs, H. E., and D. E. Bullard. “Immunology of transplantation in the central nervous system.” Appl Neurophysiol 51, no. 6 (1988): 278–96. https://doi.org/10.1159/000099973.Full Text Link to Item
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Pizzo, S. V., S. Rajagopalan, P. A. Roche, H. E. Fuchs, S. R. Feldman, and S. L. Gonias. “Specificity of alpha 2-macroglobulin covalent cross-linking for the active domain of proteinases.” Biol Chem Hoppe Seyler 367, no. 11 (November 1986): 1177–82. https://doi.org/10.1515/bchm3.1986.367.2.1177.Full Text Link to Item
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Hoffman, M., H. E. Fuchs, and S. V. Pizzo. “The macrophage-mediated regulation of hepatocyte synthesis of antithrombin III and alpha 1-proteinase inhibitor.” Thromb Res 41, no. 5 (March 1, 1986): 707–15. https://doi.org/10.1016/0049-3848(86)90368-3.Full Text Link to Item
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Pizzo, S. V., D. B. Petruska, K. A. Doman, S. J. Soong, and H. E. Fuchs. “Releasable vascular plasminogen activator and thrombotic strokes.” Am J Med 79, no. 4 (October 1985): 407–11. https://doi.org/10.1016/0002-9343(85)90026-9.Full Text Link to Item
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Fuchs, H. E., H. Berger, and S. V. Pizzo. “Catabolism of human tissue plasminogen activator in mice.” Blood 65, no. 3 (March 1985): 539–44.Link to Item
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Fuchs, H. E., H. G. Trapp, M. J. Griffith, H. R. Roberts, and S. V. Pizzo. “Regulation of factor IXa in vitro in human and mouse plasma and in vivo in the mouse. Role of the endothelium and the plasma proteinase inhibitors.” J Clin Invest 73, no. 6 (June 1984): 1696–1703. https://doi.org/10.1172/JCI111377.Full Text Link to Item
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Fuchs, H. E., G. K. Michalopoulos, and S. V. Pizzo. “Hepatocyte uptake of alpha 1-proteinase inhibitor-trypsin complexes in vitro: evidence for a shared uptake mechanism for proteinase complexes of alpha 1-proteinase inhibitor and antithrombin III.” J Cell Biochem 25, no. 4 (1984): 231–43. https://doi.org/10.1002/jcb.240250405.Full Text Link to Item
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Fuchs, H. E., M. A. Shifman, G. Michalopoulos, and S. V. Pizzo. “Hepatocyte receptors for antithrombin III-proteinase complexes.” J Cell Biochem 24, no. 3 (1984): 197–206. https://doi.org/10.1002/jcb.240240302.Full Text Link to Item
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Fuchs, H. E., and S. V. Pizzo. “Regulation of factor Xa in vitro in human and mouse plasma and in vivo in mouse. Role of the endothelium and plasma proteinase inhibitors.” J Clin Invest 72, no. 6 (December 1983): 2041–49. https://doi.org/10.1172/JCI111169.Full Text Link to Item
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Gonias, S. L., H. E. Fuchs, and S. V. Pizzo. “A unique pathway for the plasma elimination of alpha 2-antiplasmin-protease complexes in mice.” Thromb Haemost 48, no. 2 (October 29, 1982): 208–10.Link to Item
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Fuchs, H. E., M. A. Shifman, and S. V. Pizzo. “In vivo catabolism of alpha 1-proteinase inhibitor-trypsin, antithrombin III-thrombin and alpha 2-macroglobulin-methylamine.” Biochim Biophys Acta 716, no. 2 (May 27, 1982): 151–57. https://doi.org/10.1016/0304-4165(82)90263-x.Full Text Link to Item
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Fisher, R. G., N. E. Woods, H. E. Fuchs, and R. M. Sweet. “Three-dimensional structures of C-phycocyanin and B-phycoerythrin at 5-A resolution.” J Biol Chem 255, no. 11 (June 10, 1980): 5082–89.Link to Item
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Sweet, R. M., H. E. Fuchs, R. G. Fisher, and A. N. Glazer. “Preliminary crystallographic investigations of two phycobiliproteins.” J Biol Chem 252, no. 22 (November 25, 1977): 8258–60.Link to Item
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Book Sections
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Fuchs, H. E. “Congenital neurosurgical problems.” In Emergency Approaches to Neurosurgical Conditions, 65–69, 2015. https://doi.org/10.1007/978-3-319-10693-9_5.Full Text
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Other Articles
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Rasheed, B. K., R. E. McLendon, H. S. Friedman, A. H. Friedman, H. E. Fuchs, D. D. Bigner, and S. H. Bigner. “Chromosome 10 deletion mapping in human gliomas: a common deletion region in 10q25.” Oncogene, June 1, 1995.Link to Item
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Lee, V. S., J. M. Provenzale, H. E. Fuchs, A. Osumi, and R. E. McLendon. “Post-traumatic epidermoid cyst: CT appearance.” J Comput Assist Tomogr, 1995. https://doi.org/10.1097/00004728-199501000-00032.Full Text Link to Item
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Furie, D. M., G. J. Felsberg, R. D. Tien, H. S. Friedman, H. Fuchs, and R. McLendon. “MRI of gangliocytoma of cerebellum and spinal cord.” J Comput Assist Tomogr, 1993. https://doi.org/10.1097/00004728-199305000-00031.Full Text Link to Item
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Fuchs, H. E., and S. V. Pizzo. “Catabolism of antithrombin III-protease complexes.” Thromb Res, October 15, 1983. https://doi.org/10.1016/0049-3848(83)90037-3.Full Text Link to Item
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Conference Papers
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Cummings, T. J., K. R. Bulsara, R. E. McLendon, H. E. Fuchs, and T. M. George. “Pathology of the normal versus the tethered filum terminale.” In Journal of Neuropathology and Experimental Neurology, 60:553–553. AMER ASSN NEUROPATHOLOGISTS INC, 2001.Link to Item
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Cummings, T. J., H. E. Fuchs, and T. M. George. “Pathology of the filum terminale in the tethered spinal cord syndrome.” In Modern Pathology, 14:6P-6P. NATURE PUBLISHING GROUP, 2001.Link to Item
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Cummings, T. J., H. E. Fuchs, and T. M. George. “Pathology of the filum terminale in the tethered spinal cord syndrome.” In Laboratory Investigation, 81:6P-6P. NATURE PUBLISHING GROUP, 2001.Link to Item
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McLendon, R. E., H. S. Friedman, D. C. Lonuee, H. E. Fuchs, and R. B. Hessler. “SYNCHRONOUS EPENDYMO-GLIOMAS.” In Journal of Neuropathology and Experimental Neurology, 54:422–422. Oxford University Press (OUP), 1995. https://doi.org/10.1097/00005072-199505000-00062.Full Text
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Archer, G. E., J. M. Schuster, H. E. Fuchs, A. Guaspari, D. P. Bigner, H. S. Friedman, and R. E. McLendon. “NEUROPATHOLOGY OF MULTIPLE VERSUS SINGLE DOSE INTRATHECAL MELPHALAN IN RATS.” In Journal of Neuropathology and Experimental Neurology, 52:298–298. Oxford University Press (OUP), 1993. https://doi.org/10.1097/00005072-199305000-00152.Full Text
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Fuchs, H. E., G. E. Archer, J. M. Schuster, O. M. Colvin, S. H. Bigner, L. H. Muhlbaier, H. S. Friedman, and D. D. Bigner. “A NUDE RAT MODEL OF LEPTOMENINGEAL TUMOR DISSEMINATION (LTD) OF HUMAN MEDULLOBLASTOMA.” In Journal of Neuropathology and Experimental Neurology, 48:356–356. Oxford University Press (OUP), 1989. https://doi.org/10.1097/00005072-198905000-00173.Full Text
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HOFFMAN, M. R., H. E. FUCHS, and S. V. PIZZO. “SYNTHESIS OF ANTITHROMBIN-III BY CULTURED RAT HEPATOCYTES.” In Laboratory Investigation, 50:A26–A26. WILLIAMS & WILKINS, 1984.Link to Item
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FUCHS, H. E., and S. V. PIZZO. “THE CATABOLISM OF HUMAN FACTOR-XA IN A MOUSE MODEL.” In Federation Proceedings, 42:1030–1030. FEDERATION AMER SOC EXP BIOL, 1983.Link to Item
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