Herbert Edgar Fuchs | Scholars@Duke

Herbert Edgar Fuchs
Professor of Neurosurgery

Clinical neuro-oncology research including collaborations studying molecular genetics of childhood brain tumors.
Potential role of the free electron laser in surgery of pediatric brain tumors. Current work includes animal models with human brain tumor xenografts in preclinical studies.
Collaboration with the neurooncology laboratory of Dr. Darell Bigner in preclinical studies of new therapeutic agents.

Current Appointments & Affiliations

Professor of Neurosurgery, Neurosurgery, Neurosurgery 2017
Professor of Pediatrics, Pediatrics, Clinical Science Departments 2017
Assistant Professor of Pathology, Pathology, Clinical Science Departments 2017
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1992

Contact Information

4544 Hospital South, Box 3807, Durham, NC 27710
Box 3807, Durham, NC 27710
fuchs001@mc.duke.edu (919) 681-0894

Background
Education, Training, & Certifications
- M.D., Duke University 1984
- Ph.D., Duke University 1984
Previous Appointments & Affiliations
- Assistant Professor of Pediatrics, Pediatrics, Clinical Science Departments 2017 - 2018
- Assistant Professor of Pediatrics, Pediatrics, Clinical Science Departments 1995 - 2017
- Associate Professor of Neurosurgery, Neurosurgery, Neurosurgery 2002 - 2017
- Assistant Professor of Pathology, Pathology, Clinical Science Departments 1995 - 2016
- Associate Professor of Surgery, Neurosurgery, Neurosurgery 1996 - 2002
- Assistant Professor of Pediatric Neurosurgery in the Department of Surgery, Neurosurgery, Neurosurgery 1993 - 1996
Research
Selected Grants
- Research Training In Neuro-Oncology awarded by National Institutes of Health 1998 - 2016
- Linkage and candidate gene analysis in non-syndromic Chiari type I awarded by National Institutes of Health 2009 - 2015
- Research Training In Neuro-Oncology awarded by National Institutes of Health 2005 - 2010
- Src On Primary And Matastatic Tumors Of The Cns awarded by National Institutes of Health 1994 - 1999
- Src On Primary And Metastatic Tumors Of The Cns awarded by National Institutes of Health 1997 - 1999
- Src On Malignant Human Gliomas And Medulloblastomas awarded by National Institutes of Health 1993 - 1994
External Relationships
- North Carolina Physicians Advisory Group
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Akbari, Syed Hassan A., Asad A. Rizvi, Travis S. CreveCoeur, Rowland H. Han, Jacob K. Greenberg, James Torner, Douglas L. Brockmeyer, et al. “Socioeconomic and demographic factors in the diagnosis and treatment of Chiari malformation type I and syringomyelia.” J Neurosurg Pediatr, December 3, 2021, 1–10. https://doi.org/10.3171/2021.9.PEDS2185.
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  - Hendrix, Grace, Robert Benjamin, Nancie MacIver, Daniel P. Barboriak, Herbert Fuchs, and Pinar Gumus Balikcioglu. “Pediatric Giant Prolactinoma Presenting With Acute Obstructive Hydrocephalus and Intracranial Hypertension.” J Endocr Soc 5, no. 12 (December 1, 2021): bvab160. https://doi.org/10.1210/jendso/bvab160.
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  - Park, Christine, Beiyu Liu, Stephen C. Harward, Anru R. Zhang, Jared Gloria, Hui-Jie Lee, Herbert E. Fuchs, Carrie R. Muh, Sarah E. Hodges, and Eric M. Thompson. “Ventriculomegaly and postoperative lateral/third ventricular blood as predictors of cerebrospinal fluid diversion following posterior fossa tumor resection.” J Neurosurg Pediatr 28, no. 5 (August 13, 2021): 533–43. https://doi.org/10.3171/2021.4.PEDS2188.
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  - Sadler, Brooke, Alex Skidmore, Jordan Gewirtz, Richard C. E. Anderson, Gabe Haller, Laurie L. Ackerman, P David Adelson, et al. “Extradural decompression versus duraplasty in Chiari malformation type I with syrinx: outcomes on scoliosis from the Park-Reeves Syringomyelia Research Consortium.” J Neurosurg Pediatr, June 18, 2021, 1–9. https://doi.org/10.3171/2020.12.PEDS20552.
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  - CreveCoeur, Travis S., Alexander T. Yahanda, Cormac O. Maher, Gabrielle W. Johnson, Laurie L. Ackerman, P David Adelson, Raheel Ahmed, et al. “Occipital-Cervical Fusion and Ventral Decompression in the Surgical Management of Chiari-1 Malformation and Syringomyelia: Analysis of Data From the Park-Reeves Syringomyelia Research Consortium.” Neurosurgery 88, no. 2 (January 13, 2021): 332–41. https://doi.org/10.1093/neuros/nyaa460.
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  - Monuszko, Karen, Michael Malinzak, Lexie Zidanyue Yang, Donna Niedzwiecki, Herbert Fuchs, Carrie R. Muh, Krista Gingrich, Robert Lark, and Eric M. Thompson. “Image quality of EOS low-dose radiography in comparison with conventional radiography for assessment of ventriculoperitoneal shunt integrity.” J Neurosurg Pediatr 27, no. 4 (January 8, 2021): 375–81. https://doi.org/10.3171/2020.8.PEDS20428.
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  - Muh, Carrie R., Naomi D. Chou, Shervin Rahimpour, Jordan M. Komisarow, Tracy G. Spears, Herbert E. Fuchs, Sandra Serafini, and Gerald A. Grant. “Cortical stimulation mapping for localization of visual and auditory language in pediatric epilepsy patients.” J Neurosurg Pediatr, November 8, 2019, 1–10. https://doi.org/10.3171/2019.8.PEDS1922.
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  - Strahle, Jennifer M., Rukayat Taiwo, Christine Averill, James Torner, Chevis N. Shannon, Christopher M. Bonfield, Gerald F. Tuite, et al. “Radiological and clinical predictors of scoliosis in patients with Chiari malformation type I and spinal cord syrinx from the Park-Reeves Syringomyelia Research Consortium.” J Neurosurg Pediatr, August 16, 2019, 1–8. https://doi.org/10.3171/2019.5.PEDS18527.
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  - Gupta, Nalin, Liliana C. Goumnerova, Peter Manley, Susan N. Chi, Donna Neuberg, Maneka Puligandla, Jason Fangusaro, et al. “Prospective feasibility and safety assessment of surgical biopsy for patients with newly diagnosed diffuse intrinsic pontine glioma.” Neuro Oncol 20, no. 11 (October 9, 2018): 1547–55. https://doi.org/10.1093/neuonc/noy070.
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  - Tan, Char-Loo, Daniel Landi, Herbert Fuchs, and Roger E. McLendon. “Novel case of recurrent intraventricular atypical central neurocytoma with prominent gangliogliomatous differentiation in a 10-year-old boy with 10 years of follow up.” Neuropathology 38, no. 5 (October 2018): 542–48. https://doi.org/10.1111/neup.12502.
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  - Sergesketter, Amanda R., Aladine A. Elsamadicy, David T. Lubkin, Hanna Kemeny, Stephen C. Harward, Kate B. Krucoff, Max O. Krucoff, et al. “Socioeconomic Factors, Perioperative Complications, and 30-Day Readmission Rates Associated With Delayed Cranial Vault Reconstruction for Craniosynostosis.” J Craniofac Surg 29, no. 7 (October 2018): 1767–71. https://doi.org/10.1097/SCS.0000000000004787.
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  - Narine, Kalindi Y., Christopher C. Oh, Herbert E. Fuchs, and David Van Mater. “Calvarial mass as a presenting feature of neurofibromatosis type 2 in a pediatric patient.” Am J Med Genet A 176, no. 1 (January 2018): 246–47. https://doi.org/10.1002/ajmg.a.38505.
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  - Dai, Rui, Irene J. Pien, David A. Brown, Andre Marshall, Herbert E. Fuchs, and Jeffrey R. Marcus. “Multiple Recurrent Fibromatosis With Cranial Fasciitis Characteristics in a Pediatric Patient.” J Craniofac Surg 28, no. 7 (October 2017): 1821–23. https://doi.org/10.1097/SCS.0000000000003860.
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  - Jiramongkolchai, Kim, Muhammed T. Bhatti, Herbert E. Fuchs, Thomas E. Cummings, Pawina Jiramongkolchai, and Mays A. El-Dairi. “Endodermal Cyst of the Third Nerve in a Child.” J Neuroophthalmol 37, no. 3 (September 2017): 311–13. https://doi.org/10.1097/WNO.0000000000000443.
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  - McKinnon, Elizabeth L., Andrew J. Rand, M Angelica Selim, Herbert E. Fuchs, Anne F. Buckley, and Thomas J. Cummings. “Rhabdomyomatous mesenchymal hamartoma presenting as a sacral skin tag in two neonates with spinal dysraphism.” J Cutan Pathol 42, no. 10 (October 2015): 774–78. https://doi.org/10.1111/cup.12538.
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  - Nair, Smita K., Timothy Driscoll, David Boczkowski, Robert Schmittling, Renee Reynolds, Laura A. Johnson, Gerald Grant, et al. “Ex vivo generation of dendritic cells from cryopreserved, post-induction chemotherapy, mobilized leukapheresis from pediatric patients with medulloblastoma.” J Neurooncol 125, no. 1 (October 2015): 65–74. https://doi.org/10.1007/s11060-015-1890-2.
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  - McLendon, Roger E., Eric Lipp, Diane Satterfield, Melissa Ehinger, Alan Austin, Debra Fleming, Kathryn Perkinson, et al. “Prognostic marker analysis in pediatric intracranial ependymomas.” J Neurooncol 122, no. 2 (April 2015): 255–61. https://doi.org/10.1007/s11060-014-1711-z.
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  - Lock, Eric F., Karen L. Soldano, Melanie E. Garrett, Heidi Cope, Christina A. Markunas, Herbert Fuchs, Gerald Grant, David B. Dunson, Simon G. Gregory, and Allison E. Ashley-Koch. “Joint eQTL assessment of whole blood and dura mater tissue from individuals with Chiari type I malformation.” Bmc Genomics 16 (January 22, 2015): 11. https://doi.org/10.1186/s12864-014-1211-8.
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  - Markunas, Christina A., Eric Lock, Karen Soldano, Heidi Cope, Chien-Kuang C. Ding, David S. Enterline, Gerald Grant, Herbert Fuchs, Allison E. Ashley-Koch, and Simon G. Gregory. “Identification of Chiari Type I Malformation subtypes using whole genome expression profiles and cranial base morphometrics.” Bmc Med Genomics 7 (June 25, 2014): 39. https://doi.org/10.1186/1755-8794-7-39.
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  - López, G. Y., G. A. Grant, H. E. Fuchs, L. G. Leithe, S. Gururangan, D. D. Bigner, H. Yan, R. E. McLendon, and Y. He. “Clinico-pathological description of three paediatric medulloblastoma cases with MLL2/3 gene mutations.” Neuropathol Appl Neurobiol 40, no. 2 (February 2014): 217–20. https://doi.org/10.1111/nan.12060.
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  - Markunas, Christina A., David S. Enterline, Kaitlyn Dunlap, Karen Soldano, Heidi Cope, Jeffrey Stajich, Gerald Grant, Herbert Fuchs, Simon G. Gregory, and Allison E. Ashley-Koch. “Genetic evaluation and application of posterior cranial fossa traits as endophenotypes for Chiari type I malformation.” Ann Hum Genet 78, no. 1 (January 2014): 1–12. https://doi.org/10.1111/ahg.12041.
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  - Markunas, Christina A., Karen Soldano, Kaitlyn Dunlap, Heidi Cope, Edgar Asiimwe, Jeffrey Stajich, David Enterline, et al. “Stratified whole genome linkage analysis of Chiari type I malformation implicates known Klippel-Feil syndrome genes as putative disease candidates.” Plos One 8, no. 4 (2013): e61521. https://doi.org/10.1371/journal.pone.0061521.
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  - Choi, Bryan D., Tiffany R. Hodges, Gerald A. Grant, Herbert E. Fuchs, Thomas J. Cummings, and Carrie R. Muh. “Inflammatory pseudotumor of the lateral ventricle in a pediatric patient.” Pediatr Neurosurg 48, no. 6 (2012): 374–78. https://doi.org/10.1159/000353609.
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  - Parker, Stephen R., Peggy Harris, Thomas J. Cummings, Timothy George, Herbert Fuchs, and Gerald Grant. “Complications following decompression of Chiari malformation Type I in children: dural graft or sealant?” J Neurosurg Pediatr 8, no. 2 (August 2011): 177–83. https://doi.org/10.3171/2011.5.PEDS10362.
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  - Stack, A., S. L. Peterson-Carmichael, D. E. Yin, M. L. Marti, H. Fuchs, R. Jhaveri, and D. A. Turner. “CA-MRSA brain abscess in a healthy infant.” Journal of Pediatric Infectious Diseases 6, no. 1 (April 25, 2011): 71–75. https://doi.org/10.3233/JPI-2011-0290.
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  - Aliabadi, Hamidreza, Renee Reynolds, Ciaran J. Powers, Gerald Grant, Herbert Fuchs, and Joanne Kurtzberg. “Clinical outcome of cerebrospinal fluid shunting for communicating hydrocephalus in mucopolysaccharidoses I, II, and III: a retrospective analysis of 13 patients.” Neurosurgery 67, no. 6 (December 2010): 1476–81. https://doi.org/10.1227/NEU.0b013e3181f8c11d.
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  - Karikari, Isaac O., Gerald Grant, Thomas J. Cummings, Jeffrey Petrella, and Herbert E. Fuchs. “Endodermal cyst of the oculomotor nerve.” Pediatr Neurosurg 46, no. 2 (August 2010): 155–56. https://doi.org/10.1159/000319562.
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  - Nimjee, Shahid M., Ciaran J. Powers, Roger E. McLendon, Gerald A. Grant, and Herbert E. Fuchs. “Single-stage bilateral choroid plexectomy for choroid plexus papilloma in a patient presenting with high cerebrospinal fluid output.” J Neurosurg Pediatr 5, no. 4 (April 2010): 342–45. https://doi.org/10.3171/2009.10.PEDS08454.
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  - Hughes, Betsy D., Gerald A. Grant, Thomas J. Cummings, and Herbert E. Fuchs. “Disappearing bone disease and Chiari I malformation.” Pediatr Neurosurg 46, no. 1 (2010): 58–61. https://doi.org/10.1159/000315005.
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  - Aliabadi, H., J. Miller, S. Radnakrishnan, A. I. Mehta, K. Thomas, L. Selznick, R. Goldberg, G. Grant, and H. Fuchs. “Spontaneous intrauterine "ping-pong" fracture: review and case illustration.” Neuropediatrics 40, no. 2 (April 2009): 73–75. https://doi.org/10.1055/s-0029-1234108.
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  - Waldau, Ben, Leahthan F. Domeshek, Fawn A. Leigh, Kristian C. Lum, Herbert E. Fuchs, Jeffrey R. Marcus, Srinivasan Mukundan, and Gerald A. Grant. “Spontaneous resolution of a 13-mm Chiari malformation Type I in relation to differential growth of the posterior fossa volume.” J Neurosurg Pediatr 3, no. 2 (February 2009): 110–14. https://doi.org/10.3171/2008.10.PEDS08200.
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  - Waldau, Ben, Roger E. McLendon, Herbert E. Fuchs, Timothy M. George, and Gerald A. Grant. “Few isolated neurons in hypothalamic hamartomas may cause gelastic seizures.” Pediatr Neurosurg 45, no. 3 (2009): 225–29. https://doi.org/10.1159/000224620.
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  - Gururangan, Sridharan, Jeanne Krauser, Melody A. Watral, Tim Driscoll, Nicole Larrier, David A. Reardon, Jeremy N. Rich, et al. “Efficacy of high-dose chemotherapy or standard salvage therapy in patients with recurrent medulloblastoma.” Neuro Oncol 10, no. 5 (October 2008): 745–51. https://doi.org/10.1215/15228517-2008-044.
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  - Inman, Page C., Srinivasan Mukundan, Herbert E. Fuchs, and Jeffrey R. Marcus. “Craniosynostosis and rickets.” Plast Reconstr Surg 121, no. 4 (April 2008): 217e-218e. https://doi.org/10.1097/01.prs.0000305381.61117.2f.
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  - Waldau, Ben, Gerald Grant, and Herbert Fuchs. “Development of an acquired Chiari malformation Type I in the setting of an untreated lipomyelomeningocele. Case report.” J Neurosurg Pediatr 1, no. 2 (February 2008): 164–66. https://doi.org/10.3171/PED/2008/1/2/164.
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  - Mukundan, Srinivasan, Herbert Fuchs, Michael J. Alexander, and Gerald A. Grant. “Dynamic contrast-enhanced magnetic resonance angiography of vascular malformations in pediatric patients. Case report.” J Neurosurg 107, no. 3 Suppl (September 2007): 228–31. https://doi.org/10.3171/PED-07/09/228.
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  - Rajpal, Sharad, R Shane Tubbs, Timothy George, W Jerry Oakes, Herbert E. Fuchs, Mark N. Hadley, and Bermans J. Iskandar. “Tethered cord due to spina bifida occulta presenting in adulthood: a tricenter review of 61 patients.” J Neurosurg Spine 6, no. 3 (March 2007): 210–15. https://doi.org/10.3171/spi.2007.6.3.210.
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  - Powers, Ciaran J., Herbert E. Fuchs, and Timothy M. George. “Chronic subdural hematoma of the neonate: report of two cases and literature review.” Pediatr Neurosurg 43, no. 1 (2007): 25–28. https://doi.org/10.1159/000097521.
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  - Powers, Ciaran J., Kent C. New, Roger E. McLendon, Allan H. Friedman, and Herbert E. Fuchs. “Cerebellopontine angle craniopharyngioma: case report and literature review.” Pediatr Neurosurg 43, no. 2 (2007): 158–63. https://doi.org/10.1159/000098394.
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  - Wang, P. I., J. R. Marcus, H. E. Fuchs, and S. Mukundan. “Craniosynostosis Secondary to Rickets: Manifestations on Computed Tomography.” Radiology Case Reports 2, no. 3 (January 1, 2007): 43. https://doi.org/10.2484/rcr.v2i3.43.
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  - Powers, Ciaran J., Timothy George, and Herbert E. Fuchs. “Constipation as a reversible cause of ventriculoperitoneal shunt failure. Report of two cases.” J Neurosurg 105, no. 3 Suppl (September 2006): 227–30. https://doi.org/10.3171/ped.2006.105.3.227.
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  - McGirt, Matthew J., Shahid M. Nimjee, Herbert E. Fuchs, and Timothy M. George. “Relationship of cine phase-contrast magnetic resonance imaging with outcome after decompression for Chiari I malformations.” Neurosurgery 59, no. 1 (July 2006): 140–46. https://doi.org/10.1227/01.NEU.0000219841.73999.B3.
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  - Mazur, Melissa A., Sridharan Gururangan, Julia A. Bridge, Thomas J. Cummings, Srinivasan Mukundan, Herbert Fuchs, Nicole Larrier, and Edward C. Halperin. “Intracranial Ewing sarcoma.” Pediatr Blood Cancer 45, no. 6 (November 2005): 850–56. https://doi.org/10.1002/pbc.20430.
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  - O’Connell, Martin, Terence Z. Wong, Kevin E. Forkheim, Manoj Jain, Stephen W. Shipes, and Herbert E. Fuchs. “Comparison of Tc99m-DTPA and indium-111 DTPA studies of baclofen pump function.” Clin Nucl Med 29, no. 9 (September 2004): 578–80. https://doi.org/10.1097/01.rlu.0000134995.55131.30.
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  - Cummings, T. J., T. M. George, H. E. Fuchs, and R. E. McLendon. “The pathology of extracranial scalp and skull masses in young children.” Clin Neuropathol 23, no. 1 (January 2004): 34–43.
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  - Gururangan, Sridharan, Colleen McLaughlin, Jennifer Quinn, Jeremy Rich, David Reardon, Edward C. Halperin, James Herndon, et al. “High-dose chemotherapy with autologous stem-cell rescue in children and adults with newly diagnosed pineoblastomas.” J Clin Oncol 21, no. 11 (June 1, 2003): 2187–91. https://doi.org/10.1200/JCO.2003.10.096.
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  - Villavicencio, Alan T., Jean-Christophe Leveque, Matthew J. McGirt, John S. Hopkins, Herbert E. Fuchs, and Timothy M. George. “Comparison of revision rates following endoscopically versus nonendoscopically placed ventricular shunt catheters.” Surg Neurol 59, no. 5 (May 2003): 375–79. https://doi.org/10.1016/s0090-3019(03)00070-3.
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  - McGirt, Matthew J., Aimee Zaas, Herbert E. Fuchs, Timothy M. George, Keith Kaye, and Daniel J. Sexton. “Risk factors for pediatric ventriculoperitoneal shunt infection and predictors of infectious pathogens.” Clin Infect Dis 36, no. 7 (April 1, 2003): 858–62. https://doi.org/10.1086/368191.
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  - McGirt, Matthew J., John C. Wellons, Shahid M. Nimjee, Ketan R. Bulsara, Herbert E. Fuchs, and Timothy M. George. “Comparison of total versus partial revision of initial ventriculoperitoneal shunt failures.” Pediatr Neurosurg 38, no. 1 (January 2003): 34–40. https://doi.org/10.1159/000067561.
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  - McGirt, Matthew J., Jean-Christophe Leveque, John C. Wellons, Alan T. Villavicencio, John S. Hopkins, Herbert E. Fuchs, and Timoth M. George. “Cerebrospinal fluid shunt survival and etiology of failures: a seven-year institutional experience.” Pediatr Neurosurg 36, no. 5 (May 2002): 248–55. https://doi.org/10.1159/000058428.
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  - Bulsara, K. R., A. R. Zomorodi, A. T. Villavicencio, H. Fuchs, and T. M. George. “Clinical outcome differences for lipomyelomeningoceles, intraspinal lipomas, and lipomas of the filum terminale.” Neurosurg Rev 24, no. 4 (December 2001): 192–94. https://doi.org/10.1007/s101430100177.
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  - Worley, G., J. S. Wiener, T. M. George, H. E. Fuchs, J. F. Mackey, R. D. Fitch, and K. T. Oldham. “Acute abdominal symptoms and signs in children and young adults with spina bifida: ten years' experience.” J Pediatr Surg 36, no. 9 (September 2001): 1381–86. https://doi.org/10.1053/jpsu.2001.26375.
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  - McLendon, R. E., H. S. Friedman, H. E. Fuchs, L. E. Kun, and S. H. Bigner. “Diagnostic markers in paediatric medulloblastoma: a Paediatric Oncology Group Study.” Histopathology 34, no. 2 (February 1999): 154–62. https://doi.org/10.1046/j.1365-2559.1999.00577.x.
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  - Archer, G. E., J. H. Sampson, R. E. McLendon, A. H. Friedman, O. M. Colvin, M. Rose, H. Sands, et al. “Intrathecal busulfan treatment of human neoplastic meningitis in athymic nude rats.” J Neurooncol 44, no. 3 (1999): 233–41. https://doi.org/10.1023/a:1006304424346.
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  - Lee, S. E., S. P. Johnson, L. P. Hale, J. Li, N. Bullock, H. Fuchs, A. Friedman, et al. “Analysis of DNA mismatch repair proteins in human medulloblastoma.” Clin Cancer Res 4, no. 6 (June 1998): 1415–19.
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  - Moghrabi, A., H. S. Friedman, D. M. Ashley, K. S. Bottom, T. Kerby, E. Stewart, C. Bruggers, et al. “Phase II study of carboplatin (CBDCA) in progressive low-grade gliomas.” Neurosurg Focus 4, no. 4 (April 15, 1998): e3. https://doi.org/10.3171/foc.1998.4.4.6.
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  - McCowage, G. B., H. S. Friedman, A. Moghrabi, T. Kerby, L. Ferrell, E. Stewart, M. Duncan-Brown, et al. “Activity of high-dose cyclophosphamide in the treatment of childhood malignant gliomas.” Med Pediatr Oncol 30, no. 2 (February 1998): 75–80. https://doi.org/10.1002/(sici)1096-911x(199802)30:2<75::aid-mpo1>3.0.co;2-x.
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  - Slavik, T., R. C. Bentley, L. Gray, H. E. Fuchs, and R. E. McLendon. “Solitary fibrous tumor of the meninges occurring after irradiation of a mixed germ cell tumor of the pineal gland.” Clin Neuropathol 17, no. 1 (January 1998): 55–60.
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  - Sampson, J. H., D. M. Ashley, G. E. Archer, H. E. Fuchs, G. Dranoff, L. P. Hale, and D. D. Bigner. “Characterization of a spontaneous murine astrocytoma and abrogation of its tumorigenicity by cytokine secretion.” Neurosurgery 41, no. 6 (December 1997): 1365–72. https://doi.org/10.1097/00006123-199712000-00024.
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  - Bigner, S. H., R. E. McLendon, H. Fuchs, P. E. McKeever, and H. S. Friedman. “Chromosomal characteristics of childhood brain tumors.” Cancer Genet Cytogenet 97, no. 2 (September 1997): 125–34. https://doi.org/10.1016/s0165-4608(96)00404-9.
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  - Ashley, D. M., R. E. Coleman, H. Fuchs, G. Dear, B. Ginsberg, F. M. Zalduondo, H. S. Friedman, and D. Longee. “Chronic CSF leak into the peritoneal cavity shown by radionuclide cisternography. Successful treatment with an epidural blood patch.” Clin Nucl Med 22, no. 6 (June 1997): 390–92. https://doi.org/10.1097/00003072-199706000-00010.
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  - Moghrabi, A., R. Tien, H. Fuchs, D. Longee, R. McLendon, and H. S. Friedman. “False positive images in the follow-up of patients with brain tumors.” Med Pediatr Oncol 28, no. 2 (February 1997): 127–31. https://doi.org/10.1002/(sici)1096-911x(199702)28:2<127::aid-mpo6>3.0.co;2-m.
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  - Sampson, J. H., G. E. Archer, D. M. Ashley, H. E. Fuchs, L. P. Hale, G. Dranoff, and D. D. Bigner. “Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system.” Proc Natl Acad Sci U S A 93, no. 19 (September 17, 1996): 10399–404. https://doi.org/10.1073/pnas.93.19.10399.
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  - McCowage, G., R. Tien, R. McLendon, G. Felsberg, H. Fuchs, M. L. Graham, J. Kurtzberg, et al. “Successful treatment of childhood pilocytic astrocytomas metastatic to the leptomeninges with high-dose cyclophosphamide.” Med Pediatr Oncol 27, no. 1 (July 1996): 32–39. https://doi.org/10.1002/(SICI)1096-911X(199607)27:1<32::AID-MPO7>3.0.CO;2-V.
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  - Ashley, D. M., D. Longee, R. Tien, H. Fuchs, M. L. Graham, J. Kurtzberg, J. Casey, et al. “Treatment of patients with pineoblastoma with high dose cyclophosphamide.” Med Pediatr Oncol 26, no. 6 (June 1996): 387–92. https://doi.org/10.1002/(SICI)1096-911X(199606)26:6<387::AID-MPO3>3.0.CO;2-D.
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  - Caress, J. B., V. Nohria, H. Fuchs, and R. M. Boustany. “Torticollis acquired in late infancy due to a cerebellar gangliocytoma.” Int J Pediatr Otorhinolaryngol 36, no. 1 (June 1996): 39–44. https://doi.org/10.1016/0165-5876(95)01320-2.
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  - Blaeker, H., B. K. Rasheed, R. E. McLendon, H. S. Friedman, S. K. Batra, H. E. Fuchs, and S. H. Bigner. “Microsatellite analysis of childhood brain tumors.” Genes Chromosomes Cancer 15, no. 1 (January 1996): 54–63. https://doi.org/10.1002/(SICI)1098-2264(199601)15:1<54::AID-GCC8>3.0.CO;2-3.
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  - Bigner, D. D., G. E. Archer, R. E. McLendon, H. S. Friedman, H. E. Fuchs, L. H. Pai, J. E. Herndon, and I. H. Pastan. “Efficacy of compartmental administration of immunotoxin LMB-1 (B3-LysPE38) in a rat model of carcinomatous meningitis.” Clin Cancer Res 1, no. 12 (December 1995): 1545–55.
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  - Lirng, J. F., D. S. Enterline, R. D. Tien, H. Fuchs, H. S. Friedman, K. S. Ellington, and R. P. McLendon. “MRI of papillary meningiomas in children.” Pediatr Radiol 25 Suppl 1 (November 1995): S9-13.
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  - Kurpad, S. N., H. S. Friedman, G. E. Archer, R. E. McLendon, W. M. Petros, H. E. Fuchs, A. Guaspari, and D. D. Bigner. “Intraarterial administration of melphalan for treatment of intracranial human glioma xenografts in athymic rats.” Cancer Res 55, no. 17 (September 1, 1995): 3803–9.
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  - Moghrabi, A., H. Fuchs, M. Brown, S. C. Schold, M. Graham, J. Kurtzberg, R. Tien, G. Felsberg, D. H. Lachance, and O. M. Colvin. “Cyclophosphamide in combination with sargramostim for treatment of recurrent medulloblastoma.” Med Pediatr Oncol 25, no. 3 (September 1995): 190–96. https://doi.org/10.1002/mpo.2950250306.
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  - Lachance, D. H., D. Oette, S. C. Schold, M. Brown, J. Kurtzberg, M. L. Graham, R. Tien, G. Felsberg, O. M. Colvin, and A. Moghrabi. “Dose escalation trial of cyclophosphamide with Sargramostim in the treatment of central nervous system (CNS) neoplasms.” Med Pediatr Oncol 24, no. 4 (April 1995): 241–47. https://doi.org/10.1002/mpo.2950240406.
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  - Pastan, I. H., G. E. Archer, R. E. McLendon, H. S. Friedman, H. E. Fuchs, Q. C. Wang, L. H. Pai, J. Herndon, and D. D. Bigner. “Intrathecal administration of single-chain immunotoxin, LMB-7 [B3(Fv)-PE38], produces cures of carcinomatous meningitis in a rat model.” Proc Natl Acad Sci U S A 92, no. 7 (March 28, 1995): 2765–69. https://doi.org/10.1073/pnas.92.7.2765.
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  - Batra, S. K., R. E. McLendon, J. S. Koo, S. Castelino-Prabhu, H. E. Fuchs, J. P. Krischer, H. S. Friedman, D. D. Bigner, and S. H. Bigner. “Prognostic implications of chromosome 17p deletions in human medulloblastomas.” J Neurooncol 24, no. 1 (1995): 39–45. https://doi.org/10.1007/BF01052657.
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  - Fuchs, H. E., and D. G. McLone. “Diagnosis and management of astrocytomas occurring in the posterior fossa.” Neurosurgery Quarterly 5, no. 3 (January 1, 1995): 168–78. https://doi.org/10.1097/00013414-199509000-00002.
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  - Friedman, H. S., G. E. Archer, R. E. McLendon, J. M. Schuster, O. M. Colvin, A. Guaspari, R. Blum, P. A. Savina, H. E. Fuchs, and D. D. Bigner. “Intrathecal melphalan therapy of human neoplastic meningitis in athymic nude rats.” Cancer Res 54, no. 17 (September 1, 1994): 4710–14.
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  - Halperin, E. C., H. S. Friedman, S. C. Schold, H. E. Fuchs, W. J. Oakes, B. Hockenberger, and P. C. Burger. “Surgery, hyperfractionated craniospinal irradiation, and adjuvant chemotherapy in the management of supratentorial embryonal neuroepithelial neoplasms in children.” Surg Neurol 40, no. 4 (October 1993): 278–83. https://doi.org/10.1016/0090-3019(93)90138-q.
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  - Schuster, J. M., H. S. Friedman, G. E. Archer, H. E. Fuchs, R. E. McLendon, O. M. Colvin, and D. D. Bigner. “Intraarterial therapy of human glioma xenografts in athymic rats using 4-hydroperoxycyclophosphamide.” Cancer Res 53, no. 10 Suppl (May 15, 1993): 2338–43.
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  - Fuchs, H. E., G. E. Archer, O. M. Colvin, S. H. Bigner, J. M. Schuster, G. N. Fuller, L. H. Muhlbaier, S. C. Schold, H. S. Friedman, and D. D. Bigner. “Activity of intrathecal 4-hydroperoxycyclophosphamide in a nude rat model of human neoplastic meningitis.” Cancer Res 50, no. 6 (March 15, 1990): 1954–59.
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  - Fuchs, H. E., and D. E. Bullard. “Immunology of transplantation in the central nervous system.” Appl Neurophysiol 51, no. 6 (1988): 278–96. https://doi.org/10.1159/000099973.
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  - Pizzo, S. V., S. Rajagopalan, P. A. Roche, H. E. Fuchs, S. R. Feldman, and S. L. Gonias. “Specificity of alpha 2-macroglobulin covalent cross-linking for the active domain of proteinases.” Biol Chem Hoppe Seyler 367, no. 11 (November 1986): 1177–82. https://doi.org/10.1515/bchm3.1986.367.2.1177.
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  - Hoffman, M., H. E. Fuchs, and S. V. Pizzo. “The macrophage-mediated regulation of hepatocyte synthesis of antithrombin III and alpha 1-proteinase inhibitor.” Thromb Res 41, no. 5 (March 1, 1986): 707–15. https://doi.org/10.1016/0049-3848(86)90368-3.
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  - Pizzo, S. V., D. B. Petruska, K. A. Doman, S. J. Soong, and H. E. Fuchs. “Releasable vascular plasminogen activator and thrombotic strokes.” Am J Med 79, no. 4 (October 1985): 407–11. https://doi.org/10.1016/0002-9343(85)90026-9.
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  - Fuchs, H. E., H. Berger, and S. V. Pizzo. “Catabolism of human tissue plasminogen activator in mice.” Blood 65, no. 3 (March 1985): 539–44.
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  - Fuchs, H. E., H. G. Trapp, M. J. Griffith, H. R. Roberts, and S. V. Pizzo. “Regulation of factor IXa in vitro in human and mouse plasma and in vivo in the mouse. Role of the endothelium and the plasma proteinase inhibitors.” J Clin Invest 73, no. 6 (June 1984): 1696–1703. https://doi.org/10.1172/JCI111377.
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  - Fuchs, H. E., G. K. Michalopoulos, and S. V. Pizzo. “Hepatocyte uptake of alpha 1-proteinase inhibitor-trypsin complexes in vitro: evidence for a shared uptake mechanism for proteinase complexes of alpha 1-proteinase inhibitor and antithrombin III.” J Cell Biochem 25, no. 4 (1984): 231–43. https://doi.org/10.1002/jcb.240250405.
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  - Fuchs, H. E., M. A. Shifman, G. Michalopoulos, and S. V. Pizzo. “Hepatocyte receptors for antithrombin III-proteinase complexes.” J Cell Biochem 24, no. 3 (1984): 197–206. https://doi.org/10.1002/jcb.240240302.
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  - Fuchs, H. E., and S. V. Pizzo. “Regulation of factor Xa in vitro in human and mouse plasma and in vivo in mouse. Role of the endothelium and plasma proteinase inhibitors.” J Clin Invest 72, no. 6 (December 1983): 2041–49. https://doi.org/10.1172/JCI111169.
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  - Gonias, S. L., H. E. Fuchs, and S. V. Pizzo. “A unique pathway for the plasma elimination of alpha 2-antiplasmin-protease complexes in mice.” Thromb Haemost 48, no. 2 (October 29, 1982): 208–10.
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  - Fuchs, H. E., M. A. Shifman, and S. V. Pizzo. “In vivo catabolism of alpha 1-proteinase inhibitor-trypsin, antithrombin III-thrombin and alpha 2-macroglobulin-methylamine.” Biochim Biophys Acta 716, no. 2 (May 27, 1982): 151–57. https://doi.org/10.1016/0304-4165(82)90263-x.
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  - Fisher, R. G., N. E. Woods, H. E. Fuchs, and R. M. Sweet. “Three-dimensional structures of C-phycocyanin and B-phycoerythrin at 5-A resolution.” J Biol Chem 255, no. 11 (June 10, 1980): 5082–89.
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  - Sweet, R. M., H. E. Fuchs, R. G. Fisher, and A. N. Glazer. “Preliminary crystallographic investigations of two phycobiliproteins.” J Biol Chem 252, no. 22 (November 25, 1977): 8258–60.
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- Book Sections
  - Fuchs, H. E. “Congenital neurosurgical problems.” In Emergency Approaches to Neurosurgical Conditions, 65–69, 2015. https://doi.org/10.1007/978-3-319-10693-9_5.
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- Other Articles
  - Rasheed, B. K., R. E. McLendon, H. S. Friedman, A. H. Friedman, H. E. Fuchs, D. D. Bigner, and S. H. Bigner. “Chromosome 10 deletion mapping in human gliomas: a common deletion region in 10q25.” Oncogene, June 1, 1995.
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  - Lee, V. S., J. M. Provenzale, H. E. Fuchs, A. Osumi, and R. E. McLendon. “Post-traumatic epidermoid cyst: CT appearance.” J Comput Assist Tomogr, January 1995. https://doi.org/10.1097/00004728-199501000-00032.
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  - Furie, D. M., G. J. Felsberg, R. D. Tien, H. S. Friedman, H. Fuchs, and R. McLendon. “MRI of gangliocytoma of cerebellum and spinal cord.” J Comput Assist Tomogr, May 1993. https://doi.org/10.1097/00004728-199305000-00031.
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  - Fuchs, H. E., and S. V. Pizzo. “Catabolism of antithrombin III-protease complexes.” Thromb Res, October 15, 1983. https://doi.org/10.1016/0049-3848(83)90037-3.
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- Conference Papers
  - Cummings, T. J., K. R. Bulsara, R. E. McLendon, H. E. Fuchs, and T. M. George. “Pathology of the normal versus the tethered filum terminale.” In Journal of Neuropathology and Experimental Neurology, 60:553–553. AMER ASSN NEUROPATHOLOGISTS INC, 2001.
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  - Cummings, T. J., H. E. Fuchs, and T. M. George. “Pathology of the filum terminale in the tethered spinal cord syndrome.” In Modern Pathology, 14:6P-6P. NATURE PUBLISHING GROUP, 2001.
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  - Cummings, T. J., H. E. Fuchs, and T. M. George. “Pathology of the filum terminale in the tethered spinal cord syndrome.” In Laboratory Investigation, 81:6P-6P. NATURE PUBLISHING GROUP, 2001.
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  - McLendon, R. E., H. S. Friedman, D. C. Lonuee, H. E. Fuchs, and R. B. Hessler. “SYNCHRONOUS EPENDYMO-GLIOMAS.” In Journal of Neuropathology and Experimental Neurology, 54:422–422. Oxford University Press (OUP), 1995. https://doi.org/10.1097/00005072-199505000-00062.
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  - Archer, G. E., J. M. Schuster, H. E. Fuchs, A. Guaspari, D. P. Bigner, H. S. Friedman, and R. E. McLendon. “NEUROPATHOLOGY OF MULTIPLE VERSUS SINGLE DOSE INTRATHECAL MELPHALAN IN RATS.” In Journal of Neuropathology and Experimental Neurology, 52:298–298. Oxford University Press (OUP), 1993. https://doi.org/10.1097/00005072-199305000-00152.
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  - Fuchs, H. E., G. E. Archer, J. M. Schuster, O. M. Colvin, S. H. Bigner, L. H. Muhlbaier, H. S. Friedman, and D. D. Bigner. “A NUDE RAT MODEL OF LEPTOMENINGEAL TUMOR DISSEMINATION (LTD) OF HUMAN MEDULLOBLASTOMA.” In Journal of Neuropathology and Experimental Neurology, 48:356–356. Oxford University Press (OUP), 1989. https://doi.org/10.1097/00005072-198905000-00173.
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  - HOFFMAN, M. R., H. E. FUCHS, and S. V. PIZZO. “SYNTHESIS OF ANTITHROMBIN-III BY CULTURED RAT HEPATOCYTES.” In Laboratory Investigation, 50:A26–A26. WILLIAMS & WILKINS, 1984.
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  - FUCHS, H. E., and S. V. PIZZO. “THE CATABOLISM OF HUMAN FACTOR-XA IN A MOUSE MODEL.” In Federation Proceedings, 42:1030–1030. FEDERATION AMER SOC EXP BIOL, 1983.
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