Georgia Doris Tomaras | Scholars@Duke

Georgia Doris Tomaras
Professor in Surgery

Research in the Tomaras Laboratory in the Duke Human Vaccine Institute and Departments of Surgery, Immunology, and Molecular Genetics and Microbiology at Duke University Medical Center, focuses on the identification of immune correlates of protection for preventative vaccines and identification of the mechanisms responsible for potent inhibition of human pathogens.

Current Appointments & Affiliations

Professor in Surgery, Surgery, Surgical Sciences, Surgery 2015
Professor in Immunology, Immunology, Basic Science Departments 2015
Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2015
Member of the Duke Human Vaccine Institute, Duke Human Vaccine Institute, Institutes and Centers 2007
Affiliate, Duke Global Health Institute, Duke Global Health Institute, University Institutes and Centers 2014
Core Faculty in Innovation & Entrepreneurship, Duke Innovation & Entrepreneurship, Initiatives 2019

Contact Information

300 N Duke St, Durham, NC 27701
Box 104777 DUMC, Bay 47 Carmichael Bldg, 300 N. Duke St, Durham, NC 27701
gdt@duke.edu (919) 681-5598
Duke Identifies Shortcomings In HIV Vaccine
Duke scientists find potent antibody to HIV-1

Background
Education, Training, & Certifications
- Postdoctoral Fellowship, Center For Aids Research, Department Of Surgery, Duke University 1998 - 2001
- Ph.D., SUNY Upstate Medical University 1998
Duke Appointment History
- Associate Professor of Surgery, Surgery, Surgical Sciences, Surgery 2011 - 2015
- Associate Research Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2011 - 2015
- Associate Professor in Immunology, Immunology, Basic Science Departments 2012 - 2015
- Assistant Research Professor in Immunology, Immunology, Basic Science Departments 2005 - 2012
- Assistant Professor of Surgery, Surgery, Surgical Sciences, Surgery 2006 - 2011
- Assistant Research Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2007 - 2011
- Assistant Research Professor in Surgery, Surgery, Surgical Sciences, Surgery 2001 - 2006
Recognition
In the News
- NOV 19, 2019
  
  Global List of Highly Cited Puts Duke in Top Ten
- NOV 27, 2018
  
  Duke Faculty Plentiful On ‘Highly Cited’ List
- NOV 27, 2018
  
  Six From Duke Named Fellows of American Association for Advancement of Science
- DEC 28, 2017 Duke Health News
  
  Duke-Led Team Develops More Accurate Tool to Track New HIV Infections
- MAR 20, 2014
  
  Past HIV Vaccine Trials Reveal New Path to Success
Awards & Honors
Expertise
Global Scholarship
- Research
  - South Africa (Country)
Research
Selected Grants
- Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2025
- Viral Oncology Training Grant awarded by National Institutes of Health 1980 - 2024
- Advanced Immunobiology Traning Program for Surgeons awarded by National Institutes of Health 2019 - 2024
- Transplant Infectious Diseases Interdisciplinary Research Training Grant awarded by National Institutes of Health 2019 - 2023
- Quantitative Methods for HIV/AIDS Research awarded by National Institutes of Health 2018 - 2023
- GH-VAP: Duke Antibody Dynamics awarded by Bill and Melinda Gates Foundation 2019 - 2022
- Duke Resident Physician-Scientist Program- NIAID awarded by National Institutes of Health 2018 - 2022
- Bridging Antibody Fc-mediated Antiviral Functions Across Humans and Non-human Primates awarded by National Institutes of Health 2016 - 2021
- Nonhuman Primate Option 2 awarded by National Institutes of Health 2018 - 2021
- Statistical methods for HIV-1 immune correlates studies 2016 - 2021
- HVTN 703 2019 - 2020
- Protocol Development Assays 2019 - 2020
- HVTN Scientific Leadership 2018 - 2020
- HVTN Laboratory Center: HVTN 704 2015 - 2020
- HVTN Laboratory Center: HVTN Phase 1 2015 - 2020
- HVTN Laboratory Center: HVTN 118 2006 - 2020
- CIVICS Component A awarded by National Institutes of Health 2019 - 2020
- CARE Focus 2: Clearance of HIV Antigen-Positive Cells awarded by University of North Carolina - Chapel Hill 2016 - 2020
- Bioinformatics and Computational Biology Training Program awarded by National Institutes of Health 2005 - 2020
- Harnessing Mucin-IgG Interactions to Enhance HIV Vaccine Function awarded by Northwestern University 2016 - 2020
- PRO HIV-013 Humoral Immune Response 2018 - 2020
- Comparing HIV Mucosal Targets in US and Kenyan Populations awarded by Northwestern University 2019 - 2020
- HVTN TB Correlates Pilot Studies Supplement 2019
- Defining universal protective signatures for HIV-1 through systems vaccinology 2019
- Basic Immunology Training Program awarded by National Institutes of Health 2014 - 2019
- QBI - reagent support quote 2018 - 2019
- HIV Research for Prevention 2018: Vaccine, Microbicide and ARV-based Prevention Science (HIVR4P) awarded by National Institutes of Health 2018
- HVTN Laboratory Center: HVTN 117 2017 - 2018
- HVTN Laboratory Center: HVTN 118 2017 - 2018
- HIV Vaccine Trials Network: LC P5 PF 2015 - 2018
- HVTN - A004 2015 - 2018
- Identifying key determinants of IgG transplacental transfer from HIV-infected mothers to their fetus awarded by National Institutes of Health 2017 - 2018
- Humoral and cellular immunity during acute HIV-1 2014 - 2018
- Nonhuman Primate Core-Option 6 awarded by National Institutes of Health 2012 - 2018
- The duality of vaccine elicited HIV specific-IgA antibodies: Providing protection or diminishing protection awarded by National Institutes of Health 2016 - 2017
- HVTN 117 2016 - 2017
- Early Infection Response 2011 - 2017
- Animal Models of Infectious Diseases Part A awarded by National Institutes of Health 2010 - 2017
- Statistical methods for HIV-1 immune correlates studies 2015 - 2016
- HIV Vaccine Trials Network: LC P5 PF 2014 - 2015
- HVTN 505 Protocol 2014 - 2015
- HVTN LC: Virion Capture 2014 - 2015
- LC: HIV Vaccine Trials Network: Phase 1 PF 2014 - 2015
- McElrath Objective 3-Evaluate potential mucosal quality indicators 2014 - 2015
- Vaccine-induced HIV antibody responses in infants awarded by National Institutes of Health 2012 - 2015
- Harnessing Antibody-Mucus Interaction to Prevent HIV Transmission awarded by Northwestern University 2011 - 2015
- Education - Training awarded by University of Copenhagen 2015
- HIV-1 Gene Suppression by CD8+ T Cells awarded by National Institutes of Health 2002 - 2015
- Testing the ability of antibody-mucin interactions to provide vaccine function awarded by Northwestern University 2013 - 2015
- Epigenetic Control of the CD8+ T-cell Response to HIV awarded by National Institutes of Health 2013 - 2014
- McElrath Objective 3-Evaluate potential mucosal quality indicators 2014
- AIDS International Training and Research Program awarded by National Institutes of Health 2003 - 2014
- Non-human Primate Binding Antibody Evaluation awarded by National Institutes of Health 2008 - 2012
- Large Scale Antibody and TCell Epitope Discovery awarded by National Institutes of Health 2004 - 2011
- Elucidation of the Mechanisms of CD8+ T Cell Noncytolytic Antiviral Response awarded by National Institutes of Health 2009 - 2010
- Central Laboratory for the HIV Vaccines Trial Network awarded by National Institutes of Health 2000 - 2006
- NCRR FACSAria Cell Sorter 2004 - 2006
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Felber, Barbara K., Zhongyan Lu, Xintao Hu, Antonio Valentin, Margherita Rosati, Christopher A. L. Remmel, Joshua A. Weiner, et al. “Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge.” Cell Rep 31, no. 6 (May 12, 2020): 107624. https://doi.org/10.1016/j.celrep.2020.107624.
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  - Moodie, Zoe, Stephen R. Walsh, Fatima Laher, Lucas Maganga, Michael E. Herce, Sarita Naidoo, Mina C. Hosseinipour, et al. “Antibody and cellular responses to HIV vaccine regimens with DNA plasmid as compared with ALVAC priming: An analysis of two randomized controlled trials.” Plos Med 17, no. 5 (May 2020): e1003117. https://doi.org/10.1371/journal.pmed.1003117.
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  - Bekker, Linda-Gail, One Dintwe, Andrew Fiore-Gartland, Keren Middelkoop, Julia Hutter, Anthony Williams, April K. Randhawa, et al. “A phase 1b randomized study of the safety and immunological responses to vaccination with H4:IC31, H56:IC31, and BCG revaccination in Mycobacterium tuberculosis-uninfected adolescents in Cape Town, South Africa.” Eclinicalmedicine 21 (April 2020): 100313. https://doi.org/10.1016/j.eclinm.2020.100313.
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  - Schifanella, Luca, Susan W. Barnett, Massimiliano Bissa, Veronica Galli, Melvin N. Doster, Monica Vaccari, Georgia D. Tomaras, et al. “Correction: ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type.” Plos Pathog 16, no. 4 (April 2020): e1008531. https://doi.org/10.1371/journal.ppat.1008531.
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  - Gorini, Giacomo, Slim Fourati, Monica Vaccari, Mohammad Arif Rahman, Shari N. Gordon, Dallas R. Brown, Lynn Law, et al. “Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition.” Plos Pathog 16, no. 3 (March 2020): e1008377. https://doi.org/10.1371/journal.ppat.1008377.
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  - Silva de Castro, Isabela, Shari N. Gordon, Jun Liu, Massimiliano Bissa, Katherine McKinnon, Hung V. Trinh, Melvin N. Doster, et al. “Expression of CD40L by the ALVAC-Simian Immunodeficiency Virus Vector Abrogates T Cell Responses in Macaques.” J Virol 94, no. 6 (February 28, 2020). https://doi.org/10.1128/JVI.01933-19.
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  - Verma, Anil, Brian A. Schmidt, Sonny R. Elizaldi, Nancy K. Nguyen, Korey A. Walter, Zoltan Beck, Hung V. Trinh, et al. “Impact of Th1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques.” J Virol 94, no. 6 (February 28, 2020). https://doi.org/10.1128/JVI.01737-19.
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  - Schneider, Jeffrey R., Xiaoying Shen, Chiara Orlandi, Tinashe Nyanhete, Sheetal Sawant, Ann M. Carias, Archer D. Smith, et al. “A MUC16 IgG Binding Activity Selects for a Restricted Subset of IgG Enriched for Certain Simian Immunodeficiency Virus Epitope Specificities.” J Virol 94, no. 5 (February 14, 2020). https://doi.org/10.1128/JVI.01246-19.
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  - Van Der Meeren, Olivier, Erik Jongert, Kelly E. Seaton, Marguerite Koutsoukos, Annelies Aerssens, Caroline Brackett, Muriel Debois, et al. “Persistence of vaccine-elicited immune response up to 14 years post-HIV gp120-NefTat/AS01B vaccination.” Vaccine 38, no. 7 (February 11, 2020): 1678–89. https://doi.org/10.1016/j.vaccine.2019.12.058.
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  - Chu, Thach H., Andrew R. Crowley, Iara Backes, Cheryl Chang, Matthew Tay, Thomas Broge, Marina Tuyishime, et al. “Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies.” Plos Pathog 16, no. 2 (February 2020): e1008083. https://doi.org/10.1371/journal.ppat.1008083.
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  - Easterhoff, David, Justin Pollara, Kan Luo, William D. Tolbert, Brianna Young, Dieter Mielke, Shalini Jha, et al. “Boosting with AIDSVAX B/E Enhances Env Constant Region 1 and 2 Antibody-Dependent Cellular Cytotoxicity Breadth and Potency.” J Virol 94, no. 4 (January 31, 2020). https://doi.org/10.1128/JVI.01120-19.
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  - Kerwin, Bruce A., Chelsey Bennett, Yan Brodsky, Rutilio Clark, J Alaina Floyd, Alison Gillespie, Bryan T. Mayer, et al. “Framework Mutations of the 10-1074 bnAb Increase Conformational Stability, Manufacturability, and Stability While Preserving Full Neutralization Activity.” J Pharm Sci 109, no. 1 (January 2020): 233–46. https://doi.org/10.1016/j.xphs.2019.07.009.
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  - Westling, Ted, Michal Juraska, Kelly E. Seaton, Georgia D. Tomaras, Peter B. Gilbert, and Holly Janes. “Methods for comparing durability of immune responses between vaccine regimens in early-phase trials.” Stat Methods Med Res 29, no. 1 (January 2020): 78–93. https://doi.org/10.1177/0962280218820881.
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  - Giel-Moloney, M., M. Esteban, B. H. Oakes, M. Vaine, B. Asbach, R. Wagner, G. J. Mize, et al. “Recombinant HIV-1 vaccine candidates based on replication-defective flavivirus vector.” Sci Rep 9, no. 1 (December 27, 2019): 20005. https://doi.org/10.1038/s41598-019-56550-4.
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  - Schifanella, Luca, Susan W. Barnett, Massimiliano Bissa, Veronica Galli, Melvin N. Doster, Monica Vaccari, Georgia D. Tomaras, et al. “ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type.” Plos Pathog 15, no. 12 (December 2019): e1008121. https://doi.org/10.1371/journal.ppat.1008121.
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  - Pinto, Dora, Craig Fenwick, Christophe Caillat, Chiara Silacci, Serafima Guseva, François Dehez, Christophe Chipot, et al. “Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.” Cell Host Microbe 26, no. 5 (November 13, 2019): 623-637.e8. https://doi.org/10.1016/j.chom.2019.09.016.
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  - Kibler, Karen V., Benedikt Asbach, Beatriz Perdiguero, Juan García-Arriaza, Nicole L. Yates, Robert Parks, Sherry Stanfield-Oakley, et al. “Correction for Kibler et al., "Replication-Competent NYVAC-KC Yields Improved Immunogenicity to HIV-1 Antigens in Rhesus Macaques Compared to Nonreplicating NYVAC".” J Virol 93, no. 21 (November 1, 2019). https://doi.org/10.1128/JVI.00968-19.
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  - Li, Shuying S., Peter B. Gilbert, Lindsay N. Carpp, Chul-Woo Pyo, Holly Janes, Youyi Fong, Xiaoying Shen, et al. “Fc Gamma Receptor Polymorphisms Modulated the Vaccine Effect on HIV-1 Risk in the HVTN 505 HIV Vaccine Trial.” J Virol 93, no. 21 (November 1, 2019). https://doi.org/10.1128/JVI.02041-18.
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  - Neidich, Scott D., Youyi Fong, Shuying S. Li, Daniel E. Geraghty, Brian D. Williamson, William Chad Young, Derrick Goodman, et al. “Antibody Fc effector functions and IgG3 associate with decreased HIV-1 risk.” J Clin Invest 129, no. 11 (November 1, 2019): 4838–49. https://doi.org/10.1172/JCI126391.
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  - Pantaleo, Giuseppe, Holly Janes, Shelly Karuna, Shannon Grant, G Laissa Ouedraogo, Mary Allen, Georgia D. Tomaras, et al. “Safety and immunogenicity of a multivalent HIV vaccine comprising envelope protein with either DNA or NYVAC vectors (HVTN 096): a phase 1b, double-blind, placebo-controlled trial.” Lancet Hiv 6, no. 11 (November 2019): e737–49. https://doi.org/10.1016/S2352-3018(19)30262-0.
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  - Rouphael, Nadine G., Cecilia Morgan, Shuying S. Li, Ryan Jensen, Brittany Sanchez, Shelly Karuna, Edith Swann, et al. “DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial.” J Clin Invest 129, no. 11 (November 1, 2019): 4769–85. https://doi.org/10.1172/JCI128699.
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  - Gray, Glenda E., Ying Huang, Nicole Grunenberg, Fatima Laher, Surita Roux, Erica Andersen-Nissen, Stephen C. De Rosa, et al. “Immune correlates of the Thai RV144 HIV vaccine regimen in South Africa.” Sci Transl Med 11, no. 510 (September 18, 2019). https://doi.org/10.1126/scitranslmed.aax1880.
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  - Abdulhaqq, Shaheed A., Melween Martinez, Guobin Kang, Idia V. Rodriguez, Stephanie M. Nichols, David Beaumont, Jocelin Joseph, et al. “Repeated semen exposure decreases cervicovaginal SIVmac251 infection in rhesus macaques.” Nat Commun 10, no. 1 (August 21, 2019): 3753. https://doi.org/10.1038/s41467-019-11814-5.
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  - Nyanhete, Tinashe E., Alyse L. Frisbee, Todd Bradley, William J. Faison, Elizabeth Robins, Tamika Payne, Stephanie A. Freel, et al. “HLA class II-Restricted CD8+ T cells in HIV-1 Virus Controllers.” Sci Rep 9, no. 1 (July 15, 2019): 10165. https://doi.org/10.1038/s41598-019-46462-8.
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  - Han, Qifeng, Julia A. Jones, Nathan I. Nicely, Rachel K. Reed, Xiaoying Shen, Katayoun Mansouri, Mark Louder, et al. “Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations.” Nat Commun 10, no. 1 (July 1, 2019): 2898. https://doi.org/10.1038/s41467-019-10899-2.
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  - Shacklett, Barbara L., Julià Blanco, Lisa Hightow-Weidman, Nyaradzo Mgodi, José Alcamí, Susan Buchbinder, Mike Chirenje, et al. “HIV Research for Prevention 2018: From Research to Impact Conference Summary and Highlights.” Aids Res Hum Retroviruses 35, no. 7 (July 2019): 598–607. https://doi.org/10.1089/AID.2019.0074.
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  - Pollara, Justin, Dorothy I. Jones, Tori Huffman, R Whitney Edwards, Maria Dennis, Shuk Hang Li, Shalini Jha, et al. “Bridging Vaccine-Induced HIV-1 Neutralizing and Effector Antibody Responses in Rabbit and Rhesus Macaque Animal Models.” J Virol 93, no. 10 (May 15, 2019). https://doi.org/10.1128/JVI.02119-18.
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  - Spearman, Paul, Georgia D. Tomaras, David C. Montefiori, Ying Huang, Marnie L. Elizaga, Guido Ferrari, S Munir Alam, et al. “Rapid Boosting of HIV-1 Neutralizing Antibody Responses in Humans Following a Prolonged Immunologic Rest Period.” J Infect Dis 219, no. 11 (May 5, 2019): 1755–65. https://doi.org/10.1093/infdis/jiz008.
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  - Pittala, Srivamshi, Kenneth Bagley, Jennifer A. Schwartz, Eric P. Brown, Joshua A. Weiner, Ilia J. Prado, Wenlei Zhang, et al. “Antibody Fab-Fc properties outperform titer in predictive models of SIV vaccine-induced protection.” Mol Syst Biol 15, no. 5 (May 2, 2019): e8747. https://doi.org/10.15252/msb.20188747.
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  - Tay, Matthew Zirui, Erika L. Kunz, Aaron Deal, Lu Zhang, Kelly E. Seaton, Wes Rountree, Joshua A. Eudailey, et al. “Rare Detection of Antiviral Functions of Polyclonal IgA Isolated from Plasma and Breast Milk Compartments in Women Chronically Infected with HIV-1.” J Virol 93, no. 7 (April 1, 2019). https://doi.org/10.1128/JVI.02084-18.
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  - Sui, Yongjun, George K. Lewis, Yichuan Wang, Kurt Berckmueller, Blake Frey, Amiran Dzutsev, Diego Vargas-Inchaustegui, et al. “Mucosal vaccine efficacy against intrarectal SHIV is independent of anti-Env antibody response.” J Clin Invest 129, no. 3 (March 1, 2019): 1314–28. https://doi.org/10.1172/JCI122110.
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  - Fourati, Slim, Susan Pereira Ribeiro, Filipa Blasco Tavares Pereira Lopes, Aarthi Talla, Francois Lefebvre, Mark Cameron, J. Kaewkungwal, et al. “Integrated systems approach defines the antiviral pathways conferring protection by the RV144 HIV vaccine.” Nat Commun 10, no. 1 (February 20, 2019): 863. https://doi.org/10.1038/s41467-019-08854-2.
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  - Jones, Andrew T., Xiaoying Shen, Korey L. Walter, Celia C. LaBranche, Linda S. Wyatt, Georgia D. Tomaras, David C. Montefiori, et al. “HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge.” Nat Commun 10, no. 1 (February 18, 2019): 798. https://doi.org/10.1038/s41467-019-08739-4.
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  - Kibler, Karen V., Benedikt Asbach, Beatriz Perdiguero, Juan García-Arriaza, Nicole L. Yates, Robert Parks, Sherry Stanfield-Oakley, et al. “Replication-Competent NYVAC-KC Yields Improved Immunogenicity to HIV-1 Antigens in Rhesus Macaques Compared to Nonreplicating NYVAC.” J Virol 93, no. 3 (February 1, 2019). https://doi.org/10.1128/JVI.01513-18.
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  - Pantaleo, Giuseppe, Holly Janes, Shelly Karuna, Shannon Grant, Laissa Ouedraogo, Mary Allen, Georgia D. Tomaras, et al. “Co-Administration of HIV Env Protein with DNA and/or NYVAC Vaccines in Humans Results in Earlier and Potent Generation of Anti-Env Antibody Responses,” January 25, 2019.
  - Cohen, Yehuda Z., Allison L. Butler, Katrina Millard, Maggi Witmer-Pack, Rebeka Levin, Cecilia Unson-O’Brien, Roshni Patel, et al. “Safety, pharmacokinetics, and immunogenicity of the combination of the broadly neutralizing anti-HIV-1 antibodies 3BNC117 and 10-1074 in healthy adults: A randomized, phase 1 study.” Plos One 14, no. 8 (2019): e0219142. https://doi.org/10.1371/journal.pone.0219142.
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  - Cram, Jacob A., Andrew J. Fiore-Gartland, Sujatha Srinivasan, Shelly Karuna, Giuseppe Pantaleo, Georgia D. Tomaras, David N. Fredricks, and James G. Kublin. “Human gut microbiota is associated with HIV-reactive immunoglobulin at baseline and following HIV vaccination.” Plos One 14, no. 12 (2019): e0225622. https://doi.org/10.1371/journal.pone.0225622.
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  - Dahora, Lindsay C., Celina Jin, Rachel L. Spreng, Frederick Feely, Ryan Mathura, Kelly E. Seaton, Lu Zhang, et al. “IgA and IgG1 Specific to Vi Polysaccharide of Salmonella Typhi Correlate With Protection Status in a Typhoid Fever Controlled Human Infection Model.” Front Immunol 10 (2019): 2582. https://doi.org/10.3389/fimmu.2019.02582.
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  - Fisher, Leigh, Melissa Zinter, Sherry Stanfield-Oakley, Lindsay N. Carpp, R Whitney Edwards, Thomas Denny, Zoe Moodie, et al. “Vaccine-Induced Antibodies Mediate Higher Antibody-Dependent Cellular Cytotoxicity After Interleukin-15 Pretreatment of Natural Killer Effector Cells.” Front Immunol 10 (2019): 2741. https://doi.org/10.3389/fimmu.2019.02741.
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  - Mestecky, J., and G. D. Tomaras. “HIV-1/SIV humoral responses in external secretions.” Current Immunology Reviews 15, no. 1 (January 1, 2019): 49–62. https://doi.org/10.2174/1573395514666180528081557.
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  - Mielke, Dieter, Gama Bandawe, Justin Pollara, Melissa-Rose Abrahams, Tinashe Nyanhete, Penny L. Moore, Ruwayhida Thebus, et al. “Antibody-Dependent Cellular Cytotoxicity (ADCC)-Mediating Antibodies Constrain Neutralizing Antibody Escape Pathway.” Front Immunol 10 (2019): 2875. https://doi.org/10.3389/fimmu.2019.02875.
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  - Nyanhete, Tinashe, and Georgia D. Tomaras. “CD8+ T cells: mechanistic target of rapamycin and eukaryotic initiation factor 2 in elite HIV-1 control.” Aids 32, no. 18 (November 28, 2018): 2835–38. https://doi.org/10.1097/QAD.0000000000002008.
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  - Bar-On, Yotam, Henning Gruell, Till Schoofs, Joy A. Pai, Lilian Nogueira, Allison L. Butler, Katrina Millard, et al. “Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals.” Nat Med 24, no. 11 (November 2018): 1701–7. https://doi.org/10.1038/s41591-018-0186-4.
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  - Bradley, Todd, Dimitra Peppa, Isabela Pedroza-Pacheco, Dapeng Li, Derek W. Cain, Ricardo Henao, Vaishnavi Venkat, et al. “RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.” Cell 175, no. 2 (October 4, 2018): 387-399.e17. https://doi.org/10.1016/j.cell.2018.08.064.
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  - Ackerman, Margaret E., Jishnu Das, Srivamshi Pittala, Thomas Broge, Caitlyn Linde, Todd J. Suscovich, Eric P. Brown, et al. “Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV.” Nat Med 24, no. 10 (October 2018): 1590–98. https://doi.org/10.1038/s41591-018-0161-0.
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  - Mendoza, Pilar, Henning Gruell, Lilian Nogueira, Joy A. Pai, Allison L. Butler, Katrina Millard, Clara Lehmann, et al. “Combination therapy with anti-HIV-1 antibodies maintains viral suppression.” Nature 561, no. 7724 (September 2018): 479–84. https://doi.org/10.1038/s41586-018-0531-2.
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  - Dennison, S Moses, Matthew Reichartz, Kelly E. Seaton, Sheetij Dutta, Ulrike Wille-Reece, Adrian V. S. Hill, Katie J. Ewer, et al. “Qualified Biolayer Interferometry Avidity Measurements Distinguish the Heterogeneity of Antibody Interactions with Plasmodium falciparum Circumsporozoite Protein Antigens.” J Immunol 201, no. 4 (August 15, 2018): 1315–26. https://doi.org/10.4049/jimmunol.1800323.
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  - Singh, Shakti, Eric G. Ramírez-Salazar, Rami Doueiri, Antonio Valentin, Margherita Rosati, Xintao Hu, Brandon F. Keele, et al. “Control of Heterologous Simian Immunodeficiency Virus SIVsmE660 Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques.” J Virol 92, no. 15 (August 1, 2018). https://doi.org/10.1128/JVI.00281-18.
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  - Barouch, Dan H., Frank L. Tomaka, Frank Wegmann, Daniel J. Stieh, Galit Alter, Merlin L. Robb, Nelson L. Michael, et al. “Evaluation of a mosaic HIV-1 vaccine in a multicentre, randomised, double-blind, placebo-controlled, phase 1/2a clinical trial (APPROACH) and in rhesus monkeys (NHP 13-19).” Lancet 392, no. 10143 (July 21, 2018): 232–43. https://doi.org/10.1016/S0140-6736(18)31364-3.
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  - Bekker, Linda-Gail, Zoe Moodie, Nicole Grunenberg, Fatima Laher, Georgia D. Tomaras, Kristen W. Cohen, Mary Allen, et al. “Subtype C ALVAC-HIV and bivalent subtype C gp120/MF59 HIV-1 vaccine in low-risk, HIV-uninfected, South African adults: a phase 1/2 trial.” Lancet Hiv 5, no. 7 (July 2018): e366–78. https://doi.org/10.1016/S2352-3018(18)30071-7.
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  - Vaccari, Monica, Slim Fourati, Shari N. Gordon, Dallas R. Brown, Massimilano Bissa, Luca Schifanella, Isabela Silva de Castro, et al. “HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition.” Nat Med 24, no. 6 (June 2018): 847–56. https://doi.org/10.1038/s41591-018-0025-7.
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  - Schiffner, Torben, Jesper Pallesen, Rebecca A. Russell, Jonathan Dodd, Natalia de Val, Celia C. LaBranche, David Montefiori, et al. “Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.” Plos Pathog 14, no. 5 (May 2018): e1006986. https://doi.org/10.1371/journal.ppat.1006986.
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  - Saunders, Kevin O., Sampa Santra, Robert Parks, Nicole L. Yates, Laura L. Sutherland, Richard M. Scearce, Harikrishnan Balachandran, et al. “Immunogenicity of NYVAC Prime-Protein Boost Human Immunodeficiency Virus Type 1 Envelope Vaccination and Simian-Human Immunodeficiency Virus Challenge of Nonhuman Primates.” J Virol 92, no. 8 (April 15, 2018). https://doi.org/10.1128/JVI.02035-17.
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  - Yates, Nicole L., Allan C. deCamp, Bette T. Korber, Hua-Xin Liao, Carmela Irene, Abraham Pinter, James Peacock, et al. “HIV-1 Envelope Glycoproteins from Diverse Clades Differentiate Antibody Responses and Durability among Vaccinees.” J Virol 92, no. 8 (April 15, 2018). https://doi.org/10.1128/JVI.01843-17.
    Full Text Open Access Copy Link to Item
  - Pollara, Justin, Chiara Orlandi, Charles Beck, R Whitney Edwards, Yi Hu, Shuying Liu, Shixia Wang, et al. “Application of area scaling analysis to identify natural killer cell and monocyte involvement in the GranToxiLux antibody dependent cell-mediated cytotoxicity assay.” Cytometry A 93, no. 4 (April 2018): 436–47. https://doi.org/10.1002/cyto.a.23348.
    Full Text Open Access Copy Link to Item
  - Wills, Saintedym, Kwan-Ki Hwang, Pinghuang Liu, S Moses Dennison, Matthew Zirui Tay, Xiaoying Shen, Justin Pollara, et al. “HIV-1-Specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galactosylceramide Blocking and Phagocytosis.” J Virol 92, no. 7 (April 1, 2018). https://doi.org/10.1128/JVI.01552-17.
    Full Text Link to Item
  - Fong, Youyi, Xiaoying Shen, Vicki C. Ashley, Aaron Deal, Kelly E. Seaton, Chenchen Yu, Shannon P. Grant, et al. “Modification of the Association Between T-Cell Immune Responses and Human Immunodeficiency Virus Type 1 Infection Risk by Vaccine-Induced Antibody Responses in the HVTN 505 Trial.” J Infect Dis 217, no. 8 (March 28, 2018): 1280–88. https://doi.org/10.1093/infdis/jiy008.
    Full Text Link to Item
  - Francica, J. R., D. E. Zak, C. Linde, E. Siena, C. Johnson, M. Juraska, N. L. Yates, et al. “Erratum: Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs (Blood Advances (2017) 1:25 (2329-2342) DOI: 10.1182/bloodadvances.2017011411).” Blood Advances 2, no. 5 (March 13, 2018). https://doi.org/10.1182/bloodadvances.2018017491.
    Full Text
  - Nguyen, Quang N., David R. Martinez, Jonathon E. Himes, R. Whitney Edwards, Qifeng Han, Amit Kumar, Riley Mangan, et al. “Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys.” Retrovirology 15, no. 1 (March 9, 2018): 24. https://doi.org/10.1186/s12977-018-0406-5.
    Full Text Link to Item
  - Jones, Andrew T., Venkateswarlu Chamcha, Sannula Kesavardhana, Xiaoying Shen, David Beaumont, Raksha Das, Linda S. Wyatt, et al. “A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques.” J Virol 92, no. 5 (March 1, 2018). https://doi.org/10.1128/JVI.01796-17.
    Full Text Link to Item
  - Blasi, Maria, Donatella Negri, Celia LaBranche, S Munir Alam, Erich J. Baker, Elizabeth C. Brunner, Morgan A. Gladden, et al. “IDLV-HIV-1 Env vaccination in non-human primates induces affinity maturation of antigen-specific memory B cells.” Commun Biol 1 (2018): 134. https://doi.org/10.1038/s42003-018-0131-6.
    Full Text Open Access Copy Link to Item
  - McGuire, Erin P., Youyi Fong, Christopher Toote, Coleen K. Cunningham, Elizabeth J. McFarland, William Borkowsky, Susan Barnett, et al. “HIV-Exposed Infants Vaccinated with an MF59/Recombinant gp120 Vaccine Have Higher-Magnitude Anti-V1V2 IgG Responses than Adults Immunized with the Same Vaccine.” J Virol 92, no. 1 (January 1, 2018). https://doi.org/10.1128/JVI.01070-17.
    Full Text Link to Item
  - Vaidya, Naveen K., Ruy M. Ribeiro, Pinghuang Liu, Barton F. Haynes, Georgia D. Tomaras, and Alan S. Perelson. “Correlation Between Anti-gp41 Antibodies and Virus Infectivity Decay During Primary HIV-1 Infection.” Front Microbiol 9 (2018): 1326. https://doi.org/10.3389/fmicb.2018.01326.
    Full Text Link to Item
  - Wen, Yingxia, Hung V. Trinh, Christine E. Linton, Chiara Tani, Nathalie Norais, DeeAnn Martinez-Guzman, Priyanka Ramesh, et al. “Generation and characterization of a bivalent protein boost for future clinical trials: HIV-1 subtypes CR01_AE and B gp120 antigens with a potent adjuvant.” Plos One 13, no. 4 (2018): e0194266. https://doi.org/10.1371/journal.pone.0194266.
    Full Text Link to Item
  - Saunders, Kevin O., Laurent K. Verkoczy, Chuancang Jiang, Jinsong Zhang, Robert Parks, Haiyan Chen, Max Housman, et al. “Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models.” Cell Rep 21, no. 13 (December 26, 2017): 3681–90. https://doi.org/10.1016/j.celrep.2017.12.028.
    Full Text Link to Item
  - Seaton, Kelly E., Nathan A. Vandergrift, Aaron W. Deal, Wes Rountree, John Bainbridge, Eduard Grebe, David A. Anderson, et al. “Computational analysis of antibody dynamics identifies recent HIV-1 infection.” Jci Insight 2, no. 24 (December 21, 2017). https://doi.org/10.1172/jci.insight.94355.
    Full Text Link to Item
  - Shen, Xiaoying, Rahul Basu, Sheetal Sawant, David Beaumont, Sue Fen Kwa, Celia LaBranche, Kelly E. Seaton, et al. “HIV-1 gp120 and Modified Vaccinia Virus Ankara (MVA) gp140 Boost Immunogens Increase Immunogenicity of a DNA/MVA HIV-1 Vaccine.” J Virol 91, no. 24 (December 15, 2017). https://doi.org/10.1128/JVI.01077-17.
    Full Text Link to Item
  - Francica, Joseph R., Daniel E. Zak, Caitlyn Linde, Emilio Siena, Carrie Johnson, Michal Juraska, Nicole L. Yates, et al. “Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs.” Blood Adv 1, no. 25 (November 28, 2017): 2329–42. https://doi.org/10.1182/bloodadvances.2017011411.
    Full Text Link to Item
  - Han, Qifeng, Wilton B. Williams, Kevin O. Saunders, Kelly E. Seaton, Kevin J. Wiehe, Nathan Vandergrift, Tarra A. Von Holle, et al. “HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces gp41 Antibody Immunodominance in Rhesus Macaques.” J Virol 91, no. 21 (November 1, 2017). https://doi.org/10.1128/JVI.00923-17.
    Full Text Link to Item
  - Li, Shuying S., Nidhi K. Kochar, Marnie Elizaga, Christine M. Hay, Gregory J. Wilson, Kristen W. Cohen, Stephen C. De Rosa, et al. “DNA Priming Increases Frequency of T-Cell Responses to a Vesicular Stomatitis Virus HIV Vaccine with Specific Enhancement of CD8+ T-Cell Responses by Interleukin-12 Plasmid DNA.” Clin Vaccine Immunol 24, no. 11 (November 2017). https://doi.org/10.1128/CVI.00263-17.
    Full Text Link to Item
  - Mayer, Kenneth H., Kelly E. Seaton, Yunda Huang, Nicole Grunenberg, Abby Isaacs, Mary Allen, Julie E. Ledgerwood, et al. “Safety, pharmacokinetics, and immunological activities of multiple intravenous or subcutaneous doses of an anti-HIV monoclonal antibody, VRC01, administered to HIV-uninfected adults: Results of a phase 1 randomized trial.” Plos Med 14, no. 11 (November 2017): e1002435. https://doi.org/10.1371/journal.pmed.1002435.
    Full Text Link to Item
  - Shen, Xiaoying, Willy M. Bogers, Nicole L. Yates, Guido Ferrari, Antu K. Dey, William T. Williams, Frederick H. Jaeger, et al. “Cross-Linking of a CD4-Mimetic Miniprotein with HIV-1 Env gp140 Alters Kinetics and Specificities of Antibody Responses against HIV-1 Env in Macaques.” J Virol 91, no. 19 (October 1, 2017). https://doi.org/10.1128/JVI.00401-17.
    Full Text Link to Item
  - Wang, Kening, Georgia D. Tomaras, Sinthujan Jegaskanda, M Anthony Moody, Hua-Xin Liao, Kyle N. Goodman, Phillip W. Berman, et al. “Monoclonal Antibodies, Derived from Humans Vaccinated with the RV144 HIV Vaccine Containing the HVEM Binding Domain of Herpes Simplex Virus (HSV) Glycoprotein D, Neutralize HSV Infection, Mediate Antibody-Dependent Cellular Cytotoxicity, and Protect Mice from Ocular Challenge with HSV-1.” J Virol 91, no. 19 (October 1, 2017). https://doi.org/10.1128/JVI.00411-17.
    Full Text Link to Item
  - Meyerhoff, R Ryan, Richard M. Scearce, Damon F. Ogburn, Brad Lockwood, Joy Pickeral, Masa Kuraoka, Kara Anasti, et al. “HIV-1 Consensus Envelope-Induced Broadly Binding Antibodies.” Aids Res Hum Retroviruses 33, no. 8 (August 2017): 859–68. https://doi.org/10.1089/AID.2016.0294.
    Full Text Link to Item
  - Heit, Antje, Frank Schmitz, Sarah Gerdts, Britta Flach, Miranda S. Moore, Jonathan A. Perkins, Harlan S. Robins, et al. “Vaccination establishes clonal relatives of germinal center T cells in the blood of humans.” J Exp Med 214, no. 7 (July 3, 2017): 2139–52. https://doi.org/10.1084/jem.20161794.
    Full Text Link to Item
  - Bradley, Todd, Justin Pollara, Sampa Santra, Nathan Vandergrift, Srivamshi Pittala, Chris Bailey-Kellogg, Xiaoying Shen, et al. “Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge.” Nat Commun 8 (June 8, 2017): 15711. https://doi.org/10.1038/ncomms15711.
    Full Text Link to Item
  - García-Arriaza, Juan, Beatriz Perdiguero, Jonathan L. Heeney, Michael S. Seaman, David C. Montefiori, Nicole L. Yates, Georgia D. Tomaras, et al. “HIV/AIDS Vaccine Candidates Based on Replication-Competent Recombinant Poxvirus NYVAC-C-KC Expressing Trimeric gp140 and Gag-Derived Virus-Like Particles or Lacking the Viral Molecule B19 That Inhibits Type I Interferon Activate Relevant HIV-1-Specific B and T Cell Immune Functions in Nonhuman Primates.” J Virol 91, no. 9 (May 1, 2017). https://doi.org/10.1128/JVI.02182-16.
    Full Text Link to Item
  - Martinez, David R., Nathan Vandergrift, Ayooluwa O. Douglas, Erin McGuire, John Bainbridge, Nathan I. Nicely, David C. Montefiori, Georgia D. Tomaras, Genevieve G. Fouda, and Sallie R. Permar. “Maternal Binding and Neutralizing IgG Responses Targeting the C-Terminal Region of the V3 Loop Are Predictive of Reduced Peripartum HIV-1 Transmission Risk.” J Virol 91, no. 9 (May 1, 2017). https://doi.org/10.1128/JVI.02422-16.
    Full Text Link to Item
  - Zurawski, Gerard, Xiaoying Shen, Sandra Zurawski, Georgia D. Tomaras, David C. Montefiori, Mario Roederer, Guido Ferrari, et al. “Superiority in Rhesus Macaques of Targeting HIV-1 Env gp140 to CD40 versus LOX-1 in Combination with Replication-Competent NYVAC-KC for Induction of Env-Specific Antibody and T Cell Responses.” J Virol 91, no. 9 (May 1, 2017). https://doi.org/10.1128/JVI.01596-16.
    Full Text Link to Item
  - Knox, James J., Marcus Buggert, Lela Kardava, Kelly E. Seaton, Michael A. Eller, David H. Canaday, Merlin L. Robb, et al. “T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response.” Jci Insight 2, no. 8 (April 20, 2017). https://doi.org/10.1172/jci.insight.92943.
    Full Text Link to Item
  - Rerks-Ngarm, Supachai, Punnee Pitisuttithum, Jean-Louis Excler, Sorachai Nitayaphan, Jaranit Kaewkungwal, Nakorn Premsri, Prayura Kunasol, et al. “Randomized, Double-Blind Evaluation of Late Boost Strategies for HIV-Uninfected Vaccine Recipients in the RV144 HIV Vaccine Efficacy Trial.” J Infect Dis 215, no. 8 (April 15, 2017): 1255–63. https://doi.org/10.1093/infdis/jix099.
    Full Text Link to Item
  - Galarza-Muñoz, Gaddiel, Farren B. S. Briggs, Irina Evsyukova, Geraldine Schott-Lerner, Edward M. Kennedy, Tinashe Nyanhete, Liuyang Wang, et al. “Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk.” Cell 169, no. 1 (March 23, 2017): 72-84.e13. https://doi.org/10.1016/j.cell.2017.03.007.
    Full Text Link to Item
  - Ferrari, Guido, Justin Pollara, Georgia D. Tomaras, and Barton F. Haynes. “Humoral and Innate Antiviral Immunity as Tools to Clear Persistent HIV Infection.” J Infect Dis 215, no. suppl_3 (March 15, 2017): S152–59. https://doi.org/10.1093/infdis/jiw555.
    Full Text Link to Item
  - Saunders, Kevin O., Nathan I. Nicely, Kevin Wiehe, Mattia Bonsignori, R Ryan Meyerhoff, Robert Parks, William E. Walkowicz, et al. “Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates.” Cell Rep 18, no. 9 (February 28, 2017): 2175–88. https://doi.org/10.1016/j.celrep.2017.02.003.
    Full Text Link to Item
  - Huang, Yunda, Lily Zhang, Holly Janes, Nicole Frahm, Abby Isaacs, Jerome H. Kim, David Montefiori, M Julie McElrath, Georgia D. Tomaras, and Peter B. Gilbert. “Predictors of durable immune responses six months after the last vaccination in preventive HIV vaccine trials.” Vaccine 35, no. 8 (February 22, 2017): 1184–93. https://doi.org/10.1016/j.vaccine.2016.09.053.
    Full Text Link to Item
  - Easterhoff, David, M Anthony Moody, Daniela Fera, Hao Cheng, Margaret Ackerman, Kevin Wiehe, Kevin O. Saunders, et al. “Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.” Plos Pathog 13, no. 2 (February 2017): e1006182. https://doi.org/10.1371/journal.ppat.1006182.
    Full Text Link to Item
  - Wiehe, Kevin, Nathan I. Nicely, Bradley Lockwood, Masayuki Kuraoka, Kara Anasti, Sabrina Arora, Cindy M. Bowman, et al. “Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice.” J Immunol 198, no. 3 (February 1, 2017): 1047–55. https://doi.org/10.4049/jimmunol.1601640.
    Full Text Link to Item
  - Williams, LaTonya D., Gilad Ofek, Sebastian Schätzle, Jonathan R. McDaniel, Xiaozhi Lu, Nathan I. Nicely, Liming Wu, et al. “Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.” Sci Immunol 2, no. 7 (January 27, 2017). https://doi.org/10.1126/sciimmunol.aal2200.
    Full Text Link to Item
  - Bolton, Diane L., Kaimei Song, Georgia D. Tomaras, Srinivas Rao, and Mario Roederer. “Unique cellular and humoral immunogenicity profiles generated by aerosol, intranasal, or parenteral vaccination in rhesus macaques.” Vaccine 35, no. 4 (January 23, 2017): 639–46. https://doi.org/10.1016/j.vaccine.2016.12.008.
    Full Text Link to Item
  - Buchbinder, Susan P., Nicole A. Grunenberg, Brittany J. Sanchez, Kelly E. Seaton, Guido Ferrari, M Anthony Moody, Nicole Frahm, et al. “Immunogenicity of a novel Clade B HIV-1 vaccine combination: Results of phase 1 randomized placebo controlled trial of an HIV-1 GM-CSF-expressing DNA prime with a modified vaccinia Ankara vaccine boost in healthy HIV-1 uninfected adults.” Plos One 12, no. 7 (2017): e0179597. https://doi.org/10.1371/journal.pone.0179597.
    Full Text Link to Item
  - Chang, WL William, Denise F. Gonzalez, Hung T. Kieu, Luis D. Castillo, Ilhem Messaoudi, Xiaoying Shen, Georgia D. Tomaras, Barbara L. Shacklett, Peter A. Barry, and Ellen E. Sparger. “Changes in Circulating B Cell Subsets Associated with Aging and Acute SIV Infection in Rhesus Macaques.” Plos One 12, no. 1 (2017): e0170154. https://doi.org/10.1371/journal.pone.0170154.
    Full Text Link to Item
  - Gilbert, Peter B., Jean-Louis Excler, Georgia D. Tomaras, Lindsay N. Carpp, Barton F. Haynes, Hua-Xin Liao, David C. Montefiori, et al. “Antibody to HSV gD peptide induced by vaccination does not protect against HSV-2 infection in HSV-2 seronegative women.” Plos One 12, no. 5 (2017): e0176428. https://doi.org/10.1371/journal.pone.0176428.
    Full Text Link to Item
  - Ramesh, Akshaya, Sam Darko, Axin Hua, Glenn Overman, Amy Ransier, Joseph R. Francica, Ashley Trama, et al. “Structure and Diversity of the Rhesus Macaque Immunoglobulin Loci through Multiple De Novo Genome Assemblies.” Front Immunol 8 (2017): 1407. https://doi.org/10.3389/fimmu.2017.01407.
    Full Text Link to Item
  - Tomaras, Georgia D., and Stanley A. Plotkin. “Complex immune correlates of protection in HIV-1 vaccine efficacy trials.” Immunol Rev 275, no. 1 (January 2017): 245–61. https://doi.org/10.1111/imr.12514.
    Full Text Link to Item
  - deCamp, Allan C., Morgane Rolland, Paul T. Edlefsen, Eric Sanders-Buell, Breana Hall, Craig A. Magaret, Andrew J. Fiore-Gartland, et al. “Sieve analysis of breakthrough HIV-1 sequences in HVTN 505 identifies vaccine pressure targeting the CD4 binding site of Env-gp120.” Plos One 12, no. 11 (2017): e0185959. https://doi.org/10.1371/journal.pone.0185959.
    Full Text Link to Item
  - Luo, Kan, Hua-Xin Liao, Ruijun Zhang, David Easterhoff, Kevin Wiehe, Thaddeus C. Gurley, Lawrence C. Armand, et al. “Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques.” Jci Insight 1, no. 20 (December 8, 2016): e88522. https://doi.org/10.1172/jci.insight.88522.
    Full Text Link to Item
  - Astronomo, Rena D., Sampa Santra, Lamar Ballweber-Fleming, Katharine G. Westerberg, Linh Mach, Tiffany Hensley-McBain, Laura Sutherland, et al. “Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection.” Ebiomedicine 14 (December 2016): 97–111. https://doi.org/10.1016/j.ebiom.2016.11.024.
    Full Text Open Access Copy Link to Item
  - Ferrari, Guido, Barton F. Haynes, Scott Koenig, Jeffrey L. Nordstrom, David M. Margolis, and Georgia D. Tomaras. “Envelope-specific antibodies and antibody-derived molecules for treating and curing HIV infection.” Nat Rev Drug Discov 15, no. 12 (December 2016): 823–34. https://doi.org/10.1038/nrd.2016.173.
    Full Text Link to Item
  - Negri, Donatella, Maria Blasi, Celia LaBranche, Robert Parks, Harikrishnan Balachandran, Michelle Lifton, Xiaoying Shen, et al. “Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques.” Mol Ther 24, no. 11 (November 2016): 2021–32. https://doi.org/10.1038/mt.2016.123.
    Full Text Open Access Copy Link to Item
  - Negri, D, Blasi, M, LaBranche, C, Parks, R, Balachandran, H, Lifton, M, Shen, X, Denny, T, Ferrari, G, Vescio, MF, Andersen, H, Montefiori, DC, Tomaras, GD, Liao, H-X, Santra, S, Haynes, BF, Klotman, ME, and Cara, A. "Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques." MOLECULAR THERAPY 24, no. 11 (November 2016): 2021-2032. Full Text Open Access Copy Link to Item
  - Andersson, Anne-Marie C., Emeline Ragonnaud, Kelly E. Seaton, Sheetal Sawant, Antonella Folgori, Stefano Colloca, Celia Labranche, David C. Montefiori, Georgia D. Tomaras, and Peter J. Holst. “Effect of HIV-1 envelope cytoplasmic tail on adenovirus primed virus encoded virus-like particle immunizations.” Vaccine 34, no. 44 (October 17, 2016): 5344–51. https://doi.org/10.1016/j.vaccine.2016.08.089.
    Full Text Link to Item
  - Vaccari, Monica, Shari N. Gordon, Slim Fourati, Luca Schifanella, Namal P. M. Liyanage, Mark Cameron, Brandon F. Keele, et al. “Corrigendum: Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.” Nat Med 22, no. 10 (October 6, 2016): 1192. https://doi.org/10.1038/nm1016-1192a.
    Full Text Link to Item
  - Gordon, Shari N., Namal P. M. Liyanage, Melvin N. Doster, Monica Vaccari, Diego A. Vargas-Inchaustegui, Poonam Pegu, Luca Schifanella, et al. “Boosting of ALVAC-SIV Vaccine-Primed Macaques with the CD4-SIVgp120 Fusion Protein Elicits Antibodies to V2 Associated with a Decreased Risk of SIVmac251 Acquisition.” J Immunol 197, no. 7 (October 1, 2016): 2726–37. https://doi.org/10.4049/jimmunol.1600674.
    Full Text Link to Item
  - Iyer, Smita S., Sailaja Gangadhara, Blandine Victor, Xiaoying Shen, Xuemin Chen, Rafiq Nabi, Sudhir P. Kasturi, et al. “Virus-Like Particles Displaying Trimeric Simian Immunodeficiency Virus (SIV) Envelope gp160 Enhance the Breadth of DNA/Modified Vaccinia Virus Ankara SIV Vaccine-Induced Antibody Responses in Rhesus Macaques.” J Virol 90, no. 19 (October 1, 2016): 8842–54. https://doi.org/10.1128/JVI.01163-16.
    Full Text Link to Item
  - Townsley, Samantha, Zeinab Mohamed, Wenjin Guo, Jennifer McKenna, Brad Cleveland, Celia LaBranche, David Beaumont, et al. “Induction of Heterologous Tier 2 HIV-1-Neutralizing and Cross-Reactive V1/V2-Specific Antibodies in Rabbits by Prime-Boost Immunization.” J Virol 90, no. 19 (October 1, 2016): 8644–60. https://doi.org/10.1128/JVI.00853-16.
    Full Text Link to Item
  - Tay, Matthew Zirui, Pinghuang Liu, LaTonya D. Williams, Michael D. McRaven, Sheetal Sawant, Thaddeus C. Gurley, Thomas T. Xu, et al. “Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses.” Plos Pathog 12, no. 8 (August 2016): e1005817. https://doi.org/10.1371/journal.ppat.1005817.
    Full Text Link to Item
  - Abdulhaqq, S. A., C. Zorrilla, G. Kang, X. Yin, V. Tamayo, K. E. Seaton, J. Joseph, et al. “HIV-1-negative female sex workers sustain high cervical IFNɛ, low immune activation, and low expression of HIV-1-required host genes.” Mucosal Immunol 9, no. 4 (July 2016): 1027–38. https://doi.org/10.1038/mi.2015.116.
    Full Text Link to Item
  - Vaccari, Monica, Shari N. Gordon, Slim Fourati, Luca Schifanella, Namal P. M. Liyanage, Mark Cameron, Brandon F. Keele, et al. “Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.” Nat Med 22, no. 7 (July 2016): 762–70. https://doi.org/10.1038/nm.4105.
    Full Text Link to Item
  - O’Connell, Robert J., Jean-Louis Excler, Victoria R. Polonis, Silvia Ratto-Kim, Josephine Cox, Linda L. Jagodzinski, Michelle Liu, et al. “Safety and Immunogenicity of a Randomized Phase 1 Prime-Boost Trial With ALVAC-HIV (vCP205) and Oligomeric Glycoprotein 160 From HIV-1 Strains MN and LAI-2 Adjuvanted in Alum or Polyphosphazene.” J Infect Dis 213, no. 12 (June 15, 2016): 1946–54. https://doi.org/10.1093/infdis/jiw059.
    Full Text Link to Item
  - Li, Hui, Shuyi Wang, Rui Kong, Wenge Ding, Fang-Hua Lee, Zahra Parker, Eunlim Kim, et al. “Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques.” Proc Natl Acad Sci U S A 113, no. 24 (June 14, 2016): E3413–22. https://doi.org/10.1073/pnas.1606636113.
    Full Text Link to Item
  - Gray, Glenda E., Kenneth H. Mayer, Marnie L. Elizaga, Linda-Gail Bekker, Mary Allen, Lynn Morris, David Montefiori, et al. “Subtype C gp140 Vaccine Boosts Immune Responses Primed by the South African AIDS Vaccine Initiative DNA-C2 and MVA-C HIV Vaccines after More than a 2-Year Gap.” Clin Vaccine Immunol 23, no. 6 (June 2016): 496–506. https://doi.org/10.1128/CVI.00717-15.
    Full Text Link to Item
  - Le Grand, Roger, Nathalie Dereuddre-Bosquet, Stefania Dispinseri, Leslie Gosse, Delphine Desjardins, Xiaoying Shen, Monica Tolazzi, et al. “Superior Efficacy of a Human Immunodeficiency Virus Vaccine Combined with Antiretroviral Prevention in Simian-Human Immunodeficiency Virus-Challenged Nonhuman Primates.” J Virol 90, no. 11 (June 1, 2016): 5315–28. https://doi.org/10.1128/JVI.00230-16.
    Full Text Link to Item
  - Nelson, Cody S., Justin Pollara, Erika L. Kunz, Thomas L. Jeffries, Ryan Duffy, Charles Beck, Lisa Stamper, et al. “Combined HIV-1 Envelope Systemic and Mucosal Immunization of Lactating Rhesus Monkeys Induces a Robust Immunoglobulin A Isotype B Cell Response in Breast Milk.” J Virol 90, no. 10 (May 15, 2016): 4951–65. https://doi.org/10.1128/JVI.00335-16.
    Full Text Link to Item
  - Archary, D., K. E. Seaton, J. S. Passmore, L. Werner, A. Deal, L. J. Dunphy, K. B. Arnold, et al. “Distinct genital tract HIV-specific antibody profiles associated with tenofovir gel.” Mucosal Immunol 9, no. 3 (May 2016): 821–33. https://doi.org/10.1038/mi.2015.145.
    Full Text Link to Item
  - Archary, D., K. E. Seaton, J. S. Passmore, L. Werner, A. Deal, L. J. Dunphy, K. B. Arnold, et al. “Distinct genital tract HIV-specific antibody profiles associated with tenofovir gel.” Mucosal Immunol 9, no. 3 (May 2016): 834. https://doi.org/10.1038/mi.2016.21.
    Full Text Link to Item
  - Zhang, Ruijun, Laurent Verkoczy, Kevin Wiehe, S. Munir Alam, Nathan I. Nicely, Sampa Santra, Todd Bradley, et al. “Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.” Sci Transl Med 8, no. 336 (April 27, 2016): 336ra62. https://doi.org/10.1126/scitranslmed.aaf0618.
    Full Text Link to Item
  - Mkhize, Nonhlanhla N., Raveshni Durgiah, Vicki Ashley, Derseree Archary, Nigel J. Garrett, Quarraisha Abdool Karim, Salim S Abdool Karim, et al. “Broadly neutralizing antibody specificities detected in the genital tract of HIV-1 infected women.” Aids 30, no. 7 (April 24, 2016): 1005–14. https://doi.org/10.1097/QAD.0000000000001038.
    Full Text Link to Item
  - Asbach, Benedikt, Alexander Kliche, Josef Köstler, Beatriz Perdiguero, Mariano Esteban, Bertram L. Jacobs, David C. Montefiori, et al. “Potential To Streamline Heterologous DNA Prime and NYVAC/Protein Boost HIV Vaccine Regimens in Rhesus Macaques by Employing Improved Antigens.” J Virol 90, no. 8 (April 2016): 4133–49. https://doi.org/10.1128/JVI.03135-15.
    Full Text Open Access Copy Link to Item
  - Huang, Ying, Carlos DiazGranados, Holly Janes, Yunda Huang, Allan C. deCamp, Barbara Metch, Shannon Grant, et al. “Selection of HIV vaccine candidates for concurrent testing in an efficacy trial.” Curr Opin Virol 17 (April 2016): 57–65. https://doi.org/10.1016/j.coviro.2016.01.007.
    Full Text Link to Item
  - Havenar-Daughton, Colin, Madelene Lindqvist, Antje Heit, Jennifer E. Wu, Samantha M. Reiss, Kayla Kendric, Simon Bélanger, et al. “CXCL13 is a plasma biomarker of germinal center activity.” Proc Natl Acad Sci U S A 113, no. 10 (March 8, 2016): 2702–7. https://doi.org/10.1073/pnas.1520112113.
    Full Text Link to Item
  - Walsh, Stephen R., Zoe Moodie, Andrew J. Fiore-Gartland, Cecilia Morgan, Marissa B. Wilck, Scott M. Hammer, Susan P. Buchbinder, et al. “Vaccination With Heterologous HIV-1 Envelope Sequences and Heterologous Adenovirus Vectors Increases T-Cell Responses to Conserved Regions: HVTN 083.” J Infect Dis 213, no. 4 (February 15, 2016): 541–50. https://doi.org/10.1093/infdis/jiv496.
    Full Text Link to Item
  - Churchyard, Gavin, Koleka Mlisana, Shelly Karuna, Anna-Lise Williamson, Carolyn Williamson, Lynn Morris, Georgia D. Tomaras, et al. “Sequential Immunization with gp140 Boosts Immune Responses Primed by Modified Vaccinia Ankara or DNA in HIV-Uninfected South African Participants.” Plos One 11, no. 9 (2016): e0161753. https://doi.org/10.1371/journal.pone.0161753.
    Full Text Link to Item
  - Cosgrove, Catherine A., Charles J. Lacey, Alethea V. Cope, Angela Bartolf, Georgina Morris, Celine Yan, Susan Baden, et al. “Comparative Immunogenicity of HIV-1 gp140 Vaccine Delivered by Parenteral, and Mucosal Routes in Female Volunteers; MUCOVAC2, A Randomized Two Centre Study.” Plos One 11, no. 5 (2016): e0152038. https://doi.org/10.1371/journal.pone.0152038.
    Full Text Link to Item
  - Sajadi, Mohammad M., Maham Farshidpour, Eric P. Brown, Xin Ouyang, Michael S. Seaman, Marzena Pazgier, Margaret E. Ackerman, et al. “λ Light Chain Bias Associated With Enhanced Binding and Function of Anti-HIV Env Glycoprotein Antibodies.” J Infect Dis 213, no. 1 (January 1, 2016): 156–64. https://doi.org/10.1093/infdis/jiv448.
    Full Text Link to Item
  - Zurawski, Gerard, Sandra Zurawski, Anne-Laure Flamar, Laura Richert, Ralf Wagner, Georgia D. Tomaras, David C. Montefiori, et al. “Targeting HIV-1 Env gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques.” Plos One 11, no. 4 (2016): e0153484. https://doi.org/10.1371/journal.pone.0153484.
    Full Text Link to Item
  - Cubas, Rafael, Julien van Grevenynghe, Saintedym Wills, Lela Kardava, Brian H. Santich, Clarisa M. Buckner, Roshell Muir, et al. “Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection.” J Immunol 195, no. 12 (December 15, 2015): 5625–36. https://doi.org/10.4049/jimmunol.1501524.
    Full Text Link to Item
  - Corey, Lawrence, Peter B. Gilbert, Georgia D. Tomaras, Barton F. Haynes, Giuseppe Pantaleo, and Anthony S. Fauci. “Immune correlates of vaccine protection against HIV-1 acquisition.” Sci Transl Med 7, no. 310 (October 21, 2015): 310rv7. https://doi.org/10.1126/scitranslmed.aac7732.
    Full Text Link to Item
  - Pollara, Justin, Erin McGuire, Genevieve G. Fouda, Wes Rountree, Josh Eudailey, R Glenn Overman, Kelly E. Seaton, et al. “Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1.” J Virol 89, no. 19 (October 2015): 9952–61. https://doi.org/10.1128/JVI.01560-15.
    Full Text Open Access Copy Link to Item
  - Moody, M Anthony, Feng Gao, Thaddeus C. Gurley, Joshua D. Amos, Amit Kumar, Bhavna Hora, Dawn J. Marshall, et al. “Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses.” Cell Host Microbe 18, no. 3 (September 9, 2015): 354–62. https://doi.org/10.1016/j.chom.2015.08.006.
    Full Text Link to Item
  - Fuchs, Jonathan D., Ian Frank, Marnie L. Elizaga, Mary Allen, Nicole Frahm, Nidhi Kochar, Sue Li, et al. “First-in-Human Evaluation of the Safety and Immunogenicity of a Recombinant Vesicular Stomatitis Virus Human Immunodeficiency Virus-1 gag Vaccine (HVTN 090).” Open Forum Infect Dis 2, no. 3 (September 2015): ofv082. https://doi.org/10.1093/ofid/ofv082.
    Full Text Link to Item
  - Williams, Wilton B., Hua-Xin Liao, M Anthony Moody, Thomas B. Kepler, S Munir Alam, Feng Gao, Kevin Wiehe, et al. “HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies.” Science 349, no. 6249 (August 14, 2015): aab1253. https://doi.org/10.1126/science.aab1253.
    Full Text Link to Item
  - García-Arriaza, Juan, Beatriz Perdiguero, Jonathan Heeney, Michael Seaman, David C. Montefiori, Celia Labranche, Nicole L. Yates, et al. “Head-to-Head Comparison of Poxvirus NYVAC and ALVAC Vectors Expressing Identical HIV-1 Clade C Immunogens in Prime-Boost Combination with Env Protein in Nonhuman Primates.” J Virol 89, no. 16 (August 2015): 8525–39. https://doi.org/10.1128/JVI.01265-15.
    Full Text Link to Item
  - Santra, Sampa, Georgia D. Tomaras, Ranjit Warrier, Nathan I. Nicely, Hua-Xin Liao, Justin Pollara, Pinghuang Liu, et al. “Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques.” Plos Pathog 11, no. 8 (August 2015): e1005042. https://doi.org/10.1371/journal.ppat.1005042.
    Full Text Open Access Copy Link to Item
  - Shen, Xiaoying, Ryan Duffy, Robert Howington, Alethea Cope, Shanmugalakshmi Sadagopal, Haesun Park, Ranajit Pal, et al. “Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates.” J Virol 89, no. 16 (August 2015): 8643–50. https://doi.org/10.1128/JVI.03635-14.
    Full Text Link to Item
  - Prentice, Heather A., Georgia D. Tomaras, Daniel E. Geraghty, Richard Apps, Youyi Fong, Philip K. Ehrenberg, Morgane Rolland, et al. “HLA class II genes modulate vaccine-induced antibody responses to affect HIV-1 acquisition.” Sci Transl Med 7, no. 296 (July 15, 2015): 296ra112. https://doi.org/10.1126/scitranslmed.aab4005.
    Full Text Link to Item
  - Fong, Youyi, Saheli Datta, Ivelin S. Georgiev, Peter D. Kwong, and Georgia D. Tomaras. “Kernel-based logistic regression model for protein sequence without vectorialization.” Biostatistics 16, no. 3 (July 2015): 480–92. https://doi.org/10.1093/biostatistics/kxu056.
    Full Text Link to Item
  - Permar, Sallie R., Youyi Fong, Nathan Vandergrift, Genevieve G. Fouda, Peter Gilbert, Robert Parks, Frederick H. Jaeger, et al. “Maternal HIV-1 envelope-specific antibody responses and reduced risk of perinatal transmission.” J Clin Invest 125, no. 7 (July 1, 2015): 2702–6. https://doi.org/10.1172/JCI81593.
    Full Text Open Access Copy Link to Item
  - Lin, Lin, Greg Finak, Kevin Ushey, Chetan Seshadri, Thomas R. Hawn, Nicole Frahm, Thomas J. Scriba, et al. “COMPASS identifies T-cell subsets correlated with clinical outcomes.” Nat Biotechnol 33, no. 6 (June 2015): 610–16. https://doi.org/10.1038/nbt.3187.
    Full Text Link to Item
  - Fuchs, Jonathan D., Pierre-Alexandre Bart, Nicole Frahm, Cecilia Morgan, Peter B. Gilbert, Nidhi Kochar, Stephen C. DeRosa, et al. “Safety and Immunogenicity of a Recombinant Adenovirus Serotype 35-Vectored HIV-1 Vaccine in Adenovirus Serotype 5 Seronegative and Seropositive Individuals.” Journal of Aids & Clinical Research 6, no. 5 (May 23, 2015). https://doi.org/10.4172/2155-6113.1000461.
    Full Text
  - Jin, Xia, Cecilia Morgan, Xuesong Yu, Stephen DeRosa, Georgia D. Tomaras, David C. Montefiori, James Kublin, Larry Corey, Michael C. Keefer, and Michael C. NIAID HIV Vaccine Trials Network. “Multiple factors affect immunogenicity of DNA plasmid HIV vaccines in human clinical trials.” Vaccine 33, no. 20 (May 11, 2015): 2347–53. https://doi.org/10.1016/j.vaccine.2015.03.036.
    Full Text Link to Item
  - Kwa, Suefen, Shanmugalakshmi Sadagopal, Xiaoying Shen, Jung Joo Hong, Sailaja Gangadhara, Rahul Basu, Blandine Victor, et al. “CD40L-adjuvanted DNA/modified vaccinia virus Ankara simian immunodeficiency virus (SIV) vaccine enhances protection against neutralization-resistant mucosal SIV infection.” J Virol 89, no. 8 (April 2015): 4690–95. https://doi.org/10.1128/JVI.03527-14.
    Full Text Link to Item
  - Bogers, Willy M., Herman Oostermeijer, Petra Mooij, Gerrit Koopman, Ernst J. Verschoor, David Davis, Jeffrey B. Ulmer, et al. “Potent immune responses in rhesus macaques induced by nonviral delivery of a self-amplifying RNA vaccine expressing HIV type 1 envelope with a cationic nanoemulsion.” J Infect Dis 211, no. 6 (March 15, 2015): 947–55. https://doi.org/10.1093/infdis/jiu522.
    Full Text Link to Item
  - Sacha, C. R., N. Vandergrift, T. L. Jeffries, E. McGuire, G. G. Fouda, B. Liebl, D. J. Marshall, et al. “Restricted isotype, distinct variable gene usage, and high rate of gp120 specificity of HIV-1 envelope-specific B cells in colostrum compared with those in blood of HIV-1-infected, lactating African women.” Mucosal Immunol 8, no. 2 (March 2015): 316–26. https://doi.org/10.1038/mi.2014.69.
    Full Text Link to Item
  - Tomescu, Costin, Kelly E. Seaton, Peter Smith, Mack Taylor, Georgia D. Tomaras, David S. Metzger, and Luis J. Montaner. “Innate activation of MDC and NK cells in high-risk HIV-1-exposed seronegative IV-drug users who share needles when compared with low-risk nonsharing IV-drug user controls.” J Acquir Immune Defic Syndr 68, no. 3 (March 1, 2015): 264–73. https://doi.org/10.1097/QAI.0000000000000470.
    Full Text Link to Item
  - Fouda, Genevieve G., Coleen K. Cunningham, Elizabeth J. McFarland, William Borkowsky, Petronella Muresan, Justin Pollara, Lin Ye Song, et al. “Infant HIV type 1 gp120 vaccination elicits robust and durable anti-V1V2 immunoglobulin G responses and only rare envelope-specific immunoglobulin A responses.” J Infect Dis 211, no. 4 (February 15, 2015): 508–17. https://doi.org/10.1093/infdis/jiu444.
    Full Text Link to Item
  - Hancock, Gemma, Hongbing Yang, Elisabeth Yorke, Emma Wainwright, Victoria Bourne, Alyse Frisbee, Tamika L. Payne, et al. “Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses.” Plos Pathog 11, no. 2 (February 2015): e1004658. https://doi.org/10.1371/journal.ppat.1004658.
    Full Text Link to Item
  - Wiehe, Kevin, David Easterhoff, Kan Luo, Nathan I. Nicely, Todd Bradley, Frederick H. Jaeger, S Moses Dennison, et al. “Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved.” Immunity 41, no. 6 (December 18, 2014): 909–18. https://doi.org/10.1016/j.immuni.2014.11.014.
    Full Text Link to Item
  - Bart, Pierre-Alexandre, Yunda Huang, Shelly T. Karuna, Samuel Chappuis, Julien Gaillard, Nidhi Kochar, Xiaoying Shen, et al. “HIV-specific humoral responses benefit from stronger prime in phase Ib clinical trial.” J Clin Invest 124, no. 11 (November 2014): 4843–56. https://doi.org/10.1172/JCI75894.
    Full Text Link to Item
  - Frey, Sharon E., Laurence Peiperl, M Juliana McElrath, Spyros Kalams, Paul A. Goepfert, Michael C. Keefer, Lindsey R. Baden, et al. “Phase I/II randomized trial of safety and immunogenicity of LIPO-5 alone, ALVAC-HIV (vCP1452) alone, and ALVAC-HIV (vCP1452) prime/LIPO-5 boost in healthy, HIV-1-uninfected adult participants.” Clin Vaccine Immunol 21, no. 11 (November 2014): 1589–99. https://doi.org/10.1128/CVI.00450-14.
    Full Text Link to Item
  - Stieh, Daniel J., Deborah F. King, Katja Klein, Pinghuang Liu, Xiaoying Shen, Kwan Ki Hwang, Guido Ferrari, et al. “Aggregate complexes of HIV-1 induced by multimeric antibodies.” Retrovirology 11 (October 2, 2014): 78. https://doi.org/10.1186/s12977-014-0078-8.
    Full Text Open Access Copy Link to Item
  - Li, Shuying S., Peter B. Gilbert, Georgia D. Tomaras, Gustavo Kijak, Guido Ferrari, Rasmi Thomas, Chul-Woo Pyo, et al. “FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial.” J Clin Invest 124, no. 9 (September 2014): 3879–90. https://doi.org/10.1172/JCI75539.
    Full Text Link to Item
  - Payne, Tamika L., Jeff Blackinton, Alyse Frisbee, Joy Pickeral, Sheetal Sawant, Nathan A. Vandergrift, Stephanie A. Freel, Guido Ferrari, Jack D. Keene, and Georgia D. Tomaras. “Transcriptional and posttranscriptional regulation of cytokine gene expression in HIV-1 antigen-specific CD8+ T cells that mediate virus inhibition.” J Virol 88, no. 17 (September 1, 2014): 9514–28. https://doi.org/10.1128/JVI.00802-14.
    Full Text Link to Item
  - Trama, Ashley M., M Anthony Moody, S Munir Alam, Frederick H. Jaeger, Bradley Lockwood, Robert Parks, Krissey E. Lloyd, et al. “HIV-1 envelope gp41 antibodies can originate from terminal ileum B cells that share cross-reactivity with commensal bacteria.” Cell Host Microbe 16, no. 2 (August 13, 2014): 215–26. https://doi.org/10.1016/j.chom.2014.07.003.
    Full Text Open Access Copy Link to Item
  - Dennison, S Moses, Kara M. Anasti, Frederick H. Jaeger, Shelley M. Stewart, Justin Pollara, Pinghuang Liu, Erika L. Kunz, et al. “Vaccine-induced HIV-1 envelope gp120 constant region 1-specific antibodies expose a CD4-inducible epitope and block the interaction of HIV-1 gp140 with galactosylceramide.” J Virol 88, no. 16 (August 2014): 9406–17. https://doi.org/10.1128/JVI.01031-14.
    Full Text Link to Item
  - Gartland, Andrew J., Sue Li, John McNevin, Georgia D. Tomaras, Raphael Gottardo, Holly Janes, Youyi Fong, et al. “Analysis of HLA A*02 association with vaccine efficacy in the RV144 HIV-1 vaccine trial.” J Virol 88, no. 15 (August 2014): 8242–55. https://doi.org/10.1128/JVI.01164-14.
    Full Text Link to Item
  - Goepfert, Paul A., Marnie L. Elizaga, Kelly Seaton, Georgia D. Tomaras, David C. Montefiori, Alicia Sato, John Hural, et al. “Specificity and 6-month durability of immune responses induced by DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles.” J Infect Dis 210, no. 1 (July 1, 2014): 99–110. https://doi.org/10.1093/infdis/jiu003.
    Full Text Link to Item
  - Haynes, Barton F., M Anthony Moody, Munir Alam, Mattia Bonsignori, Laurent Verkoczy, Guido Ferrari, Feng Gao, Georgia D. Tomaras, Hua-Xin Liao, and Garnett Kelsoe. “Progress in HIV-1 vaccine development.” J Allergy Clin Immunol 134, no. 1 (July 2014): 3–10. https://doi.org/10.1016/j.jaci.2014.04.025.
    Full Text Link to Item
  - Pollara, Justin, Mattia Bonsignori, M Anthony Moody, Pinghuang Liu, S Munir Alam, Kwan-Ki Hwang, Thaddeus C. Gurley, et al. “HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities.” J Virol 88, no. 14 (July 2014): 7715–26. https://doi.org/10.1128/JVI.00156-14.
    Full Text Link to Item
  - Tomaras, Georgia D., and Barton F. Haynes. “Lessons from babies: inducing HIV-1 broadly neutralizing antibodies.” Nature Medicine 20, no. 6 (June 2014): 583–85. https://doi.org/10.1038/nm.3598.
    Full Text
  - Liu, Pinghuang, Latonya D. Williams, Xiaoying Shen, Mattia Bonsignori, Nathan A. Vandergrift, R Glenn Overman, M Anthony Moody, et al. “Capacity for infectious HIV-1 virion capture differs by envelope antibody specificity.” J Virol 88, no. 9 (May 2014): 5165–70. https://doi.org/10.1128/JVI.03765-13.
    Full Text Link to Item
  - Nair, Smita K., Georgia D. Tomaras, Ana Paula Sales, David Boczkowski, Cliburn Chan, Kelly Plonk, Yongting Cai, et al. “High-throughput identification and dendritic cell-based functional validation of MHC class I-restricted Mycobacterium tuberculosis epitopes.” Sci Rep 4 (April 23, 2014): 4632. https://doi.org/10.1038/srep04632.
    Full Text Link to Item
  - Bonsignori, Mattia, Kevin Wiehe, Sebastian K. Grimm, Rebecca Lynch, Guang Yang, Daniel M. Kozink, Florence Perrin, et al. “An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.” J Clin Invest 124, no. 4 (April 2014): 1835–43. https://doi.org/10.1172/JCI73441.
    Full Text Link to Item
  - Yates, Nicole L., Hua-Xin Liao, Youyi Fong, Allan deCamp, Nathan A. Vandergrift, William T. Williams, S Munir Alam, et al. “Vaccine-induced Env V1-V2 IgG3 correlates with lower HIV-1 infection risk and declines soon after vaccination.” Sci Transl Med 6, no. 228 (March 19, 2014): 228ra39. https://doi.org/10.1126/scitranslmed.3007730.
    Full Text Link to Item
  - Moody, M Anthony, Sampa Santra, Nathan A. Vandergrift, Laura L. Sutherland, Thaddeus C. Gurley, Mark S. Drinker, Ashley A. Allen, et al. “Toll-like receptor 7/8 (TLR7/8) and TLR9 agonists cooperate to enhance HIV-1 envelope antibody responses in rhesus macaques.” J Virol 88, no. 6 (March 2014): 3329–39. https://doi.org/10.1128/JVI.03309-13.
    Full Text Link to Item
  - Tomaras, Georgia D., and Barton F. Haynes. “Advancing Toward HIV-1 Vaccine Efficacy through the Intersections of Immune Correlates.” Vaccines (Basel) 2, no. 1 (March 2014): 15–35. https://doi.org/10.3390/vaccines2010015.
    Full Text Link to Item
  - Roederer, Mario, Brandon F. Keele, Stephen D. Schmidt, Rosemarie D. Mason, Hugh C. Welles, Will Fischer, Celia Labranche, et al. “Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV.” Nature 505, no. 7484 (January 23, 2014): 502–8. https://doi.org/10.1038/nature12893.
    Full Text Open Access Copy Link to Item
  - Hwang, Kwan-Ki, Ashley M. Trama, Daniel M. Kozink, Xi Chen, Kevin Wiehe, Abby J. Cooper, Shi-Mao Xia, et al. “IGHV1-69 B cell chronic lymphocytic leukemia antibodies cross-react with HIV-1 and hepatitis C virus antigens as well as intestinal commensal bacteria.” Plos One 9, no. 3 (2014): e90725. https://doi.org/10.1371/journal.pone.0090725.
    Full Text Open Access Copy Link to Item
  - Jalah, Rashmi, Viraj Kulkarni, Vainav Patel, Margherita Rosati, Candido Alicea, Jenifer Bear, Lei Yu, et al. “DNA and protein co-immunization improves the magnitude and longevity of humoral immune responses in macaques.” Plos One 9, no. 3 (2014): e91550. https://doi.org/10.1371/journal.pone.0091550.
    Full Text Link to Item
  - Kepler, Thomas B., Supriya Munshaw, Kevin Wiehe, Ruijun Zhang, Jae-Sung Yu, Christopher W. Woods, Thomas N. Denny, et al. “Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity Maturation.” Front Immunol 5 (2014): 170. https://doi.org/10.3389/fimmu.2014.00170.
    Full Text Open Access Copy Link to Item
  - Seaton, Kelly E., Lamar Ballweber, Audrey Lan, Michele Donathan, Sean Hughes, Lucia Vojtech, M Anthony Moody, et al. “HIV-1 specific IgA detected in vaginal secretions of HIV uninfected women participating in a microbicide trial in Southern Africa are primarily directed toward gp120 and gp140 specificities.” Plos One 9, no. 7 (2014): e101863. https://doi.org/10.1371/journal.pone.0101863.
    Full Text Link to Item
  - Zolla-Pazner, Susan, Allan deCamp, Peter B. Gilbert, Constance Williams, Nicole L. Yates, William T. Williams, Robert Howington, et al. “Vaccine-induced IgG antibodies to V1V2 regions of multiple HIV-1 subtypes correlate with decreased risk of HIV-1 infection.” Plos One 9, no. 2 (2014): e87572. https://doi.org/10.1371/journal.pone.0087572.
    Full Text Link to Item
  - Hammer, Scott M., Magdalena E. Sobieszczyk, Holly Janes, Shelly T. Karuna, Mark J. Mulligan, Doug Grove, Beryl A. Koblin, et al. “Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine.” N Engl J Med 369, no. 22 (November 28, 2013): 2083–92. https://doi.org/10.1056/NEJMoa1310566.
    Full Text Link to Item
  - Amos, Joshua D., Andrew B. Wilks, Genevieve G. Fouda, Shannon D. Smith, Lisa Colvin, Tatenda Mahlokozera, Carrie Ho, et al. “Lack of B cell dysfunction is associated with functional, gp120-dominant antibody responses in breast milk of simian immunodeficiency virus-infected African green monkeys.” J Virol 87, no. 20 (October 2013): 11121–34. https://doi.org/10.1128/JVI.01887-13.
    Full Text Open Access Copy Link to Item
  - Kulkarni, Viraj, Margherita Rosati, Antonio Valentin, Rashmi Jalah, Candido Alicea, Lei Yu, Yongjun Guan, et al. “Vaccination with Vaxfectin(®) adjuvanted SIV DNA induces long-lasting humoral immune responses able to reduce SIVmac251 Viremia.” Hum Vaccin Immunother 9, no. 10 (October 2013): 2069–80. https://doi.org/10.4161/hv.25442.
    Full Text Link to Item
  - Imholte, Greg C., Renan Sauteraud, Bette Korber, Robert T. Bailer, Ellen T. Turk, Xiaoying Shen, Georgia D. Tomaras, et al. “A computational framework for the analysis of peptide microarray antibody binding data with application to HIV vaccine profiling.” J Immunol Methods 395, no. 1–2 (September 30, 2013): 1–13. https://doi.org/10.1016/j.jim.2013.06.001.
    Full Text Link to Item
  - Schiffner, T., L. Kong, C. J. A. Duncan, J. W. Back, J. J. Benschop, X. Shen, P. S. Huang, et al. “Immune focusing and enhanced neutralization induced by HIV-1 gp140 chemical cross-linking.” J Virol 87, no. 18 (September 2013): 10163–72. https://doi.org/10.1128/JVI.01161-13.
    Full Text Link to Item
  - Liu, Pinghuang, Nicole L. Yates, Xiaoying Shen, Mattia Bonsignori, M Anthony Moody, Hua-Xin Liao, Youyi Fong, et al. “Infectious virion capture by HIV-1 gp120-specific IgG from RV144 vaccinees.” J Virol 87, no. 14 (July 2013): 7828–36. https://doi.org/10.1128/JVI.02737-12.
    Full Text Open Access Copy Link to Item
  - Yates, N. L., A. R. Stacey, T. L. Nolen, N. A. Vandergrift, M. A. Moody, D. C. Montefiori, K. J. Weinhold, et al. “HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life.” Mucosal Immunology 6, no. 4 (July 2013): 692–703. https://doi.org/10.1038/mi.2012.107.
    Full Text
  - Fouda, Genevieve G. A., Joshua D. Amos, Andrew B. Wilks, Justin Pollara, Caroline A. Ray, Anjali Chand, Erika L. Kunz, et al. “Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk.” J Virol 87, no. 12 (June 2013): 6986–99. https://doi.org/10.1128/JVI.00528-13.
    Full Text Link to Item
  - Tomaras, Georgia D., Guido Ferrari, Xiaoying Shen, S Munir Alam, Hua-Xin Liao, Justin Pollara, Mattia Bonsignori, et al. “Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG.” Proc Natl Acad Sci U S A 110, no. 22 (May 28, 2013): 9019–24. https://doi.org/10.1073/pnas.1301456110.
    Full Text Link to Item
  - Eckels, Josh, Cory Nathe, Elizabeth K. Nelson, Sara G. Shoemaker, Elizabeth Van Nostrand, Nicole L. Yates, Vicki C. Ashley, et al. “Quality control, analysis and secure sharing of Luminex® immunoassay data using the open source LabKey Server platform.” Bmc Bioinformatics 14 (April 30, 2013): 145. https://doi.org/10.1186/1471-2105-14-145.
    Full Text Link to Item
  - Patel, Vainav, Rashmi Jalah, Viraj Kulkarni, Antonio Valentin, Margherita Rosati, Candido Alicea, Agneta von Gegerfelt, et al. “DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge.” Proc Natl Acad Sci U S A 110, no. 8 (February 19, 2013): 2975–80. https://doi.org/10.1073/pnas.1215393110.
    Full Text Link to Item
  - Alam, S Munir, Hua-Xin Liao, Georgia D. Tomaras, Mattia Bonsignori, Chun-Yen Tsao, Kwan-Ki Hwang, Haiyan Chen, et al. “Antigenicity and immunogenicity of RV144 vaccine AIDSVAX clade E envelope immunogen is enhanced by a gp120 N-terminal deletion.” J Virol 87, no. 3 (February 2013): 1554–68. https://doi.org/10.1128/JVI.00718-12.
    Full Text Link to Item
  - Pegu, Poonam, Monica Vaccari, Shari Gordon, Brandon F. Keele, Melvin Doster, Yongjun Guan, Guido Ferrari, et al. “Antibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus SIV(mac251) acquisition in an immunization regimen that mimics the RV-144 Thai trial.” J Virol 87, no. 3 (February 2013): 1708–19. https://doi.org/10.1128/JVI.02544-12.
    Full Text Link to Item
  - Liao, Hua-Xin, Mattia Bonsignori, S Munir Alam, Jason S. McLellan, Georgia D. Tomaras, M Anthony Moody, Daniel M. Kozink, et al. “Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2.” Immunity 38, no. 1 (January 24, 2013): 176–86. https://doi.org/10.1016/j.immuni.2012.11.011.
    Full Text Link to Item
  - Gottardo, Raphael, Robert T. Bailer, Bette T. Korber, S. Gnanakaran, Joshua Phillips, Xiaoying Shen, Georgia D. Tomaras, et al. “Plasma IgG to linear epitopes in the V2 and V3 regions of HIV-1 gp120 correlate with a reduced risk of infection in the RV144 vaccine efficacy trial.” Plos One 8, no. 9 (2013): e75665. https://doi.org/10.1371/journal.pone.0075665.
    Full Text Link to Item
  - Zolla-Pazner, Susan, Allan C. deCamp, Timothy Cardozo, Nicos Karasavvas, Raphael Gottardo, Constance Williams, Daryl E. Morris, et al. “Analysis of V2 antibody responses induced in vaccinees in the ALVAC/AIDSVAX HIV-1 vaccine efficacy trial.” Plos One 8, no. 1 (2013): e53629. https://doi.org/10.1371/journal.pone.0053629.
    Full Text Link to Item
  - Bonsignori, Mattia, Justin Pollara, M Anthony Moody, Michael D. Alpert, Xi Chen, Kwan-Ki Hwang, Peter B. Gilbert, et al. “Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family.” J Virol 86, no. 21 (November 2012): 11521–32. https://doi.org/10.1128/JVI.01023-12.
    Full Text Link to Item
  - Bonsignori, Mattia, S Munir Alam, Hua-Xin Liao, Laurent Verkoczy, Georgia D. Tomaras, Barton F. Haynes, and M Anthony Moody. “HIV-1 antibodies from infection and vaccination: insights for guiding vaccine design.” Trends Microbiol 20, no. 11 (November 2012): 532–39. https://doi.org/10.1016/j.tim.2012.08.011.
    Full Text Link to Item
  - Karasavvas, Nicos, Erik Billings, Mangala Rao, Constance Williams, Susan Zolla-Pazner, Robert T. Bailer, Richard A. Koup, et al. “The Thai Phase III HIV Type 1 Vaccine trial (RV144) regimen induces antibodies that target conserved regions within the V2 loop of gp120.” Aids Res Hum Retroviruses 28, no. 11 (November 2012): 1444–57. https://doi.org/10.1089/aid.2012.0103.
    Full Text Link to Item
  - Petrovas, Constantinos, Takuya Yamamoto, Michael Y. Gerner, Kristin L. Boswell, Kaska Wloka, Emily C. Smith, David R. Ambrozak, et al. “CD4 T follicular helper cell dynamics during SIV infection.” J Clin Invest 122, no. 9 (September 2012): 3281–94. https://doi.org/10.1172/JCI63039.
    Full Text Link to Item
  - Lynch, Rebecca M., Lillian Tran, Mark K. Louder, Stephen D. Schmidt, Myron Cohen, Myron CHAVI 001 Clinical Team Members, Rebecca Dersimonian, et al. “The development of CD4 binding site antibodies during HIV-1 infection.” J Virol 86, no. 14 (July 2012): 7588–95. https://doi.org/10.1128/JVI.00734-12.
    Full Text Link to Item
  - Moody, M Anthony, Nicole L. Yates, Joshua D. Amos, Mark S. Drinker, Joshua A. Eudailey, Thaddeus C. Gurley, Dawn J. Marshall, et al. “HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages.” J Virol 86, no. 14 (July 2012): 7496–7507. https://doi.org/10.1128/JVI.00426-12.
    Full Text Link to Item
  - Freel, Stephanie A., Ralph A. Picking, Guido Ferrari, Haitao Ding, Christina Ochsenbauer, John C. Kappes, Jennifer L. Kirchherr, et al. “Initial HIV-1 antigen-specific CD8+ T cells in acute HIV-1 infection inhibit transmitted/founder virus replication.” J Virol 86, no. 12 (June 2012): 6835–46. https://doi.org/10.1128/JVI.00437-12.
    Full Text Open Access Copy Link to Item
  - Frahm, Marc A., Ralph A. Picking, JoAnn D. Kuruc, Kara S. McGee, Cynthia L. Gay, Joseph J. Eron, Charles B. Hicks, Georgia D. Tomaras, and Guido Ferrari. “CD4+CD8+ T cells represent a significant portion of the anti-HIV T cell response to acute HIV infection.” J Immunol 188, no. 9 (May 1, 2012): 4289–96. https://doi.org/10.4049/jimmunol.1103701.
    Full Text Link to Item
  - Haynes, Barton F., Peter B. Gilbert, M Juliana McElrath, Susan Zolla-Pazner, Georgia D. Tomaras, S Munir Alam, David T. Evans, et al. “Immune-correlates analysis of an HIV-1 vaccine efficacy trial.” N Engl J Med 366, no. 14 (April 5, 2012): 1275–86. https://doi.org/10.1056/NEJMoa1113425.
    Full Text Link to Item
  - Bonsignori, Mattia, David C. Montefiori, Xueling Wu, Xi Chen, Kwan-Ki Hwang, Chun-Yen Tsao, Daniel M. Kozink, et al. “Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: implications for vaccine design.” J Virol 86, no. 8 (April 2012): 4688–92. https://doi.org/10.1128/JVI.07163-11.
    Full Text Open Access Copy Link to Item
  - Montefiori, David, Haili Tang, S. Gnanakaran, Feng Gao, Mattia Bonsignori, James Binley, Georgia Tomaras, et al. “116 Autologous and Heterologous Neutralizing Antibody Responses in HIV-1 Infection.” Jaids Journal of Acquired Immune Deficiency Syndromes 59 (April 2012): 47–47. https://doi.org/10.1097/01.qai.0000413735.52728.f8.
    Full Text
  - Bolton, D. L., K. Song, R. L. Wilson, P. A. Kozlowski, G. D. Tomaras, B. F. Keele, R. V. Lovingood, S. Rao, and M. Roederer. “Comparison of systemic and mucosal vaccination: impact on intravenous and rectal SIV challenge.” Mucosal Immunol 5, no. 1 (January 2012): 41–52. https://doi.org/10.1038/mi.2011.45.
    Full Text Link to Item
  - Friedman, James, S Munir Alam, Xiaoying Shen, Shi-Mao Xia, Shelley Stewart, Kara Anasti, Justin Pollara, et al. “Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum.” Plos One 7, no. 5 (2012): e37648. https://doi.org/10.1371/journal.pone.0037648.
    Full Text Open Access Copy Link to Item
  - Baden, Lindsey R., William A. Blattner, Cecilia Morgan, Yunda Huang, Olivier D. Defawe, Magdalena E. Sobieszczyk, Nidhi Kochar, et al. “Timing of plasmid cytokine (IL-2/Ig) administration affects HIV-1 vaccine immunogenicity in HIV-seronegative subjects.” J Infect Dis 204, no. 10 (November 15, 2011): 1541–49. https://doi.org/10.1093/infdis/jir615.
    Full Text Link to Item
  - Yates, Nicole L., Judith T. Lucas, Tracy L. Nolen, Nathan A. Vandergrift, Kelly A. Soderberg, Kelly E. Seaton, Thomas N. Denny, Barton F. Haynes, Myron S. Cohen, and Georgia D. Tomaras. “Multiple HIV-1-specific IgG3 responses decline during acute HIV-1: implications for detection of incident HIV infection.” Aids 25, no. 17 (November 13, 2011): 2089–97. https://doi.org/10.1097/QAD.0b013e32834b348e.
    Full Text Open Access Copy Link to Item
  - Alam, S Munir, Hua-Xin Liao, S Moses Dennison, Frederick Jaeger, Robert Parks, Kara Anasti, Andrew Foulger, et al. “Differential reactivity of germ line allelic variants of a broadly neutralizing HIV-1 antibody to a gp41 fusion intermediate conformation.” J Virol 85, no. 22 (November 2011): 11725–31. https://doi.org/10.1128/JVI.05680-11.
    Full Text Link to Item
  - Liu, Pinghuang, R Glenn Overman, Nicole L. Yates, S Munir Alam, Nathan Vandergrift, Yue Chen, Frederik Graw, et al. “Dynamic antibody specificities and virion concentrations in circulating immune complexes in acute to chronic HIV-1 infection.” J Virol 85, no. 21 (November 2011): 11196–207. https://doi.org/10.1128/JVI.05601-11.
    Full Text Link to Item
  - Tomaras, Georgia D., James M. Binley, Elin S. Gray, Emma T. Crooks, Keiko Osawa, Penny L. Moore, Nancy Tumba, et al. “Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals.” J Virol 85, no. 21 (November 2011): 11502–19. https://doi.org/10.1128/JVI.05363-11.
    Full Text Link to Item
  - Zhu, Zhongyu, Haiyan Rebekah Qin, Weizao Chen, Qi Zhao, Xiaoying Shen, Robert Schutte, Yanping Wang, et al. “Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies.” J Virol 85, no. 21 (November 2011): 11401–8. https://doi.org/10.1128/JVI.05312-11.
    Full Text Link to Item
  - Liao, Hua-Xin, Xi Chen, Supriya Munshaw, Ruijun Zhang, Dawn J. Marshall, Nathan Vandergrift, John F. Whitesides, et al. “Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated.” J Exp Med 208, no. 11 (October 24, 2011): 2237–49. https://doi.org/10.1084/jem.20110363.
    Full Text Open Access Copy Link to Item
  - Bonsignori, Mattia, Kwan-Ki Hwang, Xi Chen, Chun-Yen Tsao, Lynn Morris, Elin Gray, Dawn J. Marshall, et al. “Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors.” J Virol 85, no. 19 (October 2011): 9998–10009. https://doi.org/10.1128/JVI.05045-11.
    Full Text Link to Item
  - Jiang, Chunlai, Nicholas F. Parrish, Craig B. Wilen, Hui Li, Yue Chen, Jeffrey W. Pavlicek, Anna Berg, et al. “Primary infection by a human immunodeficiency virus with atypical coreceptor tropism.” J Virol 85, no. 20 (October 2011): 10669–81. https://doi.org/10.1128/JVI.05249-11.
    Full Text Link to Item
  - De Rosa, Stephen C., Evan P. Thomas, John Bui, Yunda Huang, Allan deCamp, Cecilia Morgan, Spyros A. Kalams, et al. “HIV-DNA priming alters T cell responses to HIV-adenovirus vaccine even when responses to DNA are undetectable.” J Immunol 187, no. 6 (September 15, 2011): 3391–3401. https://doi.org/10.4049/jimmunol.1101421.
    Full Text Link to Item
  - Fouda, Genevieve G., Nicole L. Yates, Justin Pollara, Xiaoying Shen, Glenn R. Overman, Tatenda Mahlokozera, Andrew B. Wilks, et al. “HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies.” J Virol 85, no. 18 (September 2011): 9555–67. https://doi.org/10.1128/JVI.05174-11.
    Full Text Open Access Copy Link to Item
  - Gnanakaran, S., Tanmoy Bhattacharya, Marcus Daniels, Brandon F. Keele, Peter T. Hraber, Alan S. Lapedes, Tongye Shen, et al. “Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections.” Plos Pathog 7, no. 9 (September 2011): e1002209. https://doi.org/10.1371/journal.ppat.1002209.
    Full Text Link to Item
  - Ma, Ben-Jiang, S Munir Alam, Eden P. Go, Xiaozhi Lu, Heather Desaire, Georgia D. Tomaras, Cindy Bowman, et al. “Envelope deglycosylation enhances antigenicity of HIV-1 gp41 epitopes for both broad neutralizing antibodies and their unmutated ancestor antibodies.” Plos Pathog 7, no. 9 (September 2011): e1002200. https://doi.org/10.1371/journal.ppat.1002200.
    Full Text Link to Item
  - Gray, Elin S., M Anthony Moody, Constantinos Kurt Wibmer, Xi Chen, Dawn Marshall, Joshua Amos, Penny L. Moore, et al. “Isolation of a monoclonal antibody that targets the alpha-2 helix of gp120 and represents the initial autologous neutralizing-antibody response in an HIV-1 subtype C-infected individual.” J Virol 85, no. 15 (August 2011): 7719–29. https://doi.org/10.1128/JVI.00563-11.
    Full Text Link to Item
  - Pollara, Justin, Lydia Hart, Faraha Brewer, Joy Pickeral, Beverly Z. Packard, James A. Hoxie, Akira Komoriya, et al. “High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses.” Cytometry A 79, no. 8 (August 2011): 603–12. https://doi.org/10.1002/cyto.a.21084.
    Full Text Link to Item
  - Ferrari, Guido, Justin Pollara, Daniel Kozink, Tiara Harms, Mark Drinker, Stephanie Freel, M Anthony Moody, et al. “An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum.” J Virol 85, no. 14 (July 2011): 7029–36. https://doi.org/10.1128/JVI.00171-11.
    Full Text Link to Item
  - Flynn, Barbara J., Kathrin Kastenmüller, Ulrike Wille-Reece, Georgia D. Tomaras, Munir Alam, Ross W. Lindsay, Andres M. Salazar, et al. “Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates.” Proc Natl Acad Sci U S A 108, no. 17 (April 26, 2011): 7131–36. https://doi.org/10.1073/pnas.1103869108.
    Full Text Link to Item
  - Spearman, Paul, Michelle A. Lally, Marnie Elizaga, David Montefiori, Georgia D. Tomaras, M Juliana McElrath, John Hural, et al. “A trimeric, V2-deleted HIV-1 envelope glycoprotein vaccine elicits potent neutralizing antibodies but limited breadth of neutralization in human volunteers.” J Infect Dis 203, no. 8 (April 15, 2011): 1165–73. https://doi.org/10.1093/infdis/jiq175.
    Full Text Link to Item
  - Freel, Stephanie A., Kevin O. Saunders, and Georgia D. Tomaras. “CD8(+)T-cell-mediated control of HIV-1 and SIV infection.” Immunol Res 49, no. 1–3 (April 2011): 135–46. https://doi.org/10.1007/s12026-010-8177-7.
    Full Text Link to Item
  - Goepfert, Paul A., Marnie L. Elizaga, Alicia Sato, Li Qin, Massimo Cardinali, Christine M. Hay, John Hural, et al. “Phase 1 safety and immunogenicity testing of DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles.” J Infect Dis 203, no. 5 (March 1, 2011): 610–19. https://doi.org/10.1093/infdis/jiq105.
    Full Text Link to Item
  - Shen, Xiaoying, and Georgia D. Tomaras. “Alterations of the B-cell response by HIV-1 replication.” Curr Hiv/Aids Rep 8, no. 1 (March 2011): 23–30. https://doi.org/10.1007/s11904-010-0064-2.
    Full Text Link to Item
  - Keefer, Michael C., Sharon E. Frey, Marnie Elizaga, Barbara Metch, Stephen C. De Rosa, Paulo F. Barroso, Georgia Tomaras, et al. “A phase I trial of preventive HIV vaccination with heterologous poxviral-vectors containing matching HIV-1 inserts in healthy HIV-uninfected subjects.” Vaccine 29, no. 10 (February 24, 2011): 1948–58. https://doi.org/10.1016/j.vaccine.2010.12.104.
    Full Text Link to Item
  - Ferrari, Guido, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, et al. “Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection.” Plos Pathog 7, no. 2 (February 10, 2011): e1001273. https://doi.org/10.1371/journal.ppat.1001273.
    Full Text Link to Item
  - Haynes, Barton F., M Anthony Moody, Hua-Xin Liao, Laurent Verkoczy, and Georgia D. Tomaras. “B cell responses to HIV-1 infection and vaccination: pathways to preventing infection.” Trends Mol Med 17, no. 2 (February 2011): 108–16. https://doi.org/10.1016/j.molmed.2010.10.008.
    Full Text Link to Item
  - Churchyard, Gavin J., Cecilia Morgan, Elizabeth Adams, John Hural, Barney S. Graham, Zoe Moodie, Doug Grove, et al. “A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204).” Plos One 6, no. 8 (2011): e21225. https://doi.org/10.1371/journal.pone.0021225.
    Full Text Link to Item
  - Dennison, S Moses, Laura L. Sutherland, Frederick H. Jaeger, Kara M. Anasti, Robert Parks, Shelley Stewart, Cindy Bowman, et al. “Induction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41.” Plos One 6, no. 11 (2011): e27824. https://doi.org/10.1371/journal.pone.0027824.
    Full Text Link to Item
  - Koblin, Beryl A., Martin Casapia, Cecilia Morgan, Li Qin, Zhixue Maggie Wang, Olivier D. Defawe, Lindsey Baden, et al. “Safety and immunogenicity of an HIV adenoviral vector boost after DNA plasmid vaccine prime by route of administration: a randomized clinical trial.” Plos One 6, no. 9 (2011): e24517. https://doi.org/10.1371/journal.pone.0024517.
    Full Text Link to Item
  - Moody, M Anthony, Ruijun Zhang, Emmanuel B. Walter, Christopher W. Woods, Geoffrey S. Ginsburg, Micah T. McClain, Thomas N. Denny, et al. “H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination.” Plos One 6, no. 10 (2011): e25797. https://doi.org/10.1371/journal.pone.0025797.
    Full Text Link to Item
  - Morris, Lynn, Xi Chen, Munir Alam, Georgia Tomaras, Ruijun Zhang, Dawn J. Marshall, Bing Chen, et al. “Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting.” Plos One 6, no. 9 (2011): e23532. https://doi.org/10.1371/journal.pone.0023532.
    Full Text Link to Item
  - Saunders, Kevin O., Cavin Ward-Caviness, Robert J. Schutte, Stephanie A. Freel, R Glenn Overman, Nathan M. Thielman, Coleen K. Cunningham, Thomas B. Kepler, and Georgia D. Tomaras. “Secretion of MIP-1β and MIP-1α by CD8(+) T-lymphocytes correlates with HIV-1 inhibition independent of coreceptor usage.” Cell Immunol 266, no. 2 (2011): 154–64. https://doi.org/10.1016/j.cellimm.2010.09.011.
    Full Text Link to Item
  - Peiperl, Laurence, Cecilia Morgan, Zoe Moodie, Hongli Li, Nina Russell, Barney S. Graham, Georgia D. Tomaras, Stephen C. De Rosa, M Juliana McElrath, and M Juliana NIAID HIV Vaccine Trials Network. “Safety and immunogenicity of a replication-defective adenovirus type 5 HIV vaccine in Ad5-seronegative persons: a randomized clinical trial (HVTN 054).” Plos One 5, no. 10 (October 27, 2010): e13579. https://doi.org/10.1371/journal.pone.0013579.
    Full Text Open Access Copy Link to Item
  - Liu, Jinyan, Brandon F. Keele, Hui Li, Sheila Keating, Philip J. Norris, Angela Carville, Keith G. Mansfield, et al. “Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys.” J Virol 84, no. 19 (October 2010): 10406–12. https://doi.org/10.1128/JVI.01155-10.
    Full Text Link to Item
  - Saunders, Kevin O., Stephanie A. Freel, R Glenn Overman, Coleen K. Cunningham, and Georgia D. Tomaras. “Epigenetic regulation of CD8(+) T-lymphocyte mediated suppression of HIV-1 replication.” Virology 405, no. 1 (September 15, 2010): 234–42. https://doi.org/10.1016/j.virol.2010.06.001.
    Full Text Link to Item
  - Haynes, Barton F., Hua-Xin Liao, and Georgia D. Tomaras. “Is developing an HIV-1 vaccine possible?” Curr Opin Hiv Aids 5, no. 5 (September 2010): 362–67. https://doi.org/10.1097/COH.0b013e32833d2e90.
    Full Text Link to Item
  - Tomaras, Georgia D., and Barton F. Haynes. “Strategies for eliciting HIV-1 inhibitory antibodies.” Curr Opin Hiv Aids 5, no. 5 (September 2010): 421–27. https://doi.org/10.1097/COH.0b013e32833d2d45.
    Full Text Link to Item
  - Freel, Stephanie A., Laurie Lamoreaux, Pratip K. Chattopadhyay, Kevin Saunders, David Zarkowsky, R Glenn Overman, Christina Ochsenbauer, et al. “Phenotypic and functional profile of HIV-inhibitory CD8 T cells elicited by natural infection and heterologous prime/boost vaccination.” J Virol 84, no. 10 (May 2010): 4998–5006. https://doi.org/10.1128/JVI.00138-10.
    Full Text Link to Item
  - Moody, M Anthony, Hua-Xin Liao, S Munir Alam, Richard M. Scearce, M Kelly Plonk, Daniel M. Kozink, Mark S. Drinker, et al. “Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines.” J Exp Med 207, no. 4 (April 12, 2010): 763–76. https://doi.org/10.1084/jem.20091281.
    Full Text Open Access Copy Link to Item
  - Shen, Xiaoying, S Moses Dennison, Pinghuang Liu, Feng Gao, Frederick Jaeger, David C. Montefiori, Laurent Verkoczy, Barton F. Haynes, S Munir Alam, and Georgia D. Tomaras. “Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution.” Proc Natl Acad Sci U S A 107, no. 13 (March 30, 2010): 5972–77. https://doi.org/10.1073/pnas.0912381107.
    Full Text Link to Item
  - Nandi, Avishek, Christine L. Lavine, Pengcheng Wang, Inna Lipchina, Paul A. Goepfert, George M. Shaw, Georgia D. Tomaras, et al. “Epitopes for broad and potent neutralizing antibody responses during chronic infection with human immunodeficiency virus type 1.” Virology 396, no. 2 (January 20, 2010): 339–48. https://doi.org/10.1016/j.virol.2009.10.044.
    Full Text Link to Item
  - McMichael, Andrew J., Persephone Borrow, Georgia D. Tomaras, Nilu Goonetilleke, and Barton F. Haynes. “The immune response during acute HIV-1 infection: clues for vaccine development.” Nat Rev Immunol 10, no. 1 (January 2010): 11–23. https://doi.org/10.1038/nri2674.
    Full Text Link to Item
  - Gao, Feng, Richard M. Scearce, S Munir Alam, Bhavna Hora, Shimao Xia, Julie E. Hohm, Robert J. Parks, et al. “Cross-reactive monoclonal antibodies to multiple HIV-1 subtype and SIVcpz envelope glycoproteins.” Virology 394, no. 1 (November 10, 2009): 91–98. https://doi.org/10.1016/j.virol.2009.07.041.
    Full Text Link to Item
  - Gray, Elin S., Natasha Taylor, Diane Wycuff, Penny L. Moore, Georgia D. Tomaras, Constantinos Kurt Wibmer, Adrian Puren, et al. “Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors.” J Virol 83, no. 17 (September 2009): 8925–37. https://doi.org/10.1128/JVI.00758-09.
    Full Text Link to Item
  - Tomaras, Georgia D., and Barton F. Haynes. “HIV-1-specific antibody responses during acute and chronic HIV-1 infection.” Curr Opin Hiv Aids 4, no. 5 (September 2009): 373–79. https://doi.org/10.1097/COH.0b013e32832f00c0.
    Full Text Link to Item
  - Levesque, Marc C., M Anthony Moody, Kwan-Ki Hwang, Dawn J. Marshall, John F. Whitesides, Joshua D. Amos, Thaddeus C. Gurley, et al. “Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection.” Plos Med 6, no. 7 (July 7, 2009): e1000107. https://doi.org/10.1371/journal.pmed.1000107.
    Full Text Open Access Copy Link to Item
  - Maksaereekul, Saipiroon, Robert A. Dubie, Xiaoying Shen, Hung Kieu, Gregg A. Dean, and Ellen E. Sparger. “Vaccination with vif-deleted feline immunodeficiency virus provirus, GM-CSF, and TNF-alpha plasmids preserves global CD4 T lymphocyte function after challenge with FIV.” Vaccine 27, no. 28 (June 8, 2009): 3754–65. https://doi.org/10.1016/j.vaccine.2009.03.081.
    Full Text Link to Item
  - Miller, Heather B., Kevin O. Saunders, Georgia D. Tomaras, and Mariano A. Garcia-Blanco. “Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAs.” Plos One 4, no. 5 (May 27, 2009): e5710. https://doi.org/10.1371/journal.pone.0005710.
    Full Text Link to Item
  - Lambotte, Olivier, Guido Ferrari, Christiane Moog, Nicole L. Yates, Hua-Xin Liao, Robert J. Parks, Charles B. Hicks, et al. “Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers.” Aids 23, no. 8 (May 15, 2009): 897–906. https://doi.org/10.1097/QAD.0b013e328329f97d.
    Full Text Link to Item
  - Shen, Xiaoying, Robert J. Parks, David C. Montefiori, Jennifer L. Kirchherr, Brandon F. Keele, Julie M. Decker, William A. Blattner, et al. “In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadth.” J Virol 83, no. 8 (April 2009): 3617–25. https://doi.org/10.1128/JVI.02631-08.
    Full Text Link to Item
  - Binley, James M., Elizabeth A. Lybarger, Emma T. Crooks, Michael S. Seaman, Elin Gray, Katie L. Davis, Julie M. Decker, et al. “Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.” J Virol 82, no. 23 (December 2008): 11651–68. https://doi.org/10.1128/JVI.01762-08.
    Full Text Link to Item
  - Tomaras, Georgia D., Nicole L. Yates, Pinghuang Liu, Li Qin, Genevieve G. Fouda, Leslie L. Chavez, Allan C. Decamp, et al. “Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia.” J Virol 82, no. 24 (December 2008): 12449–63. https://doi.org/10.1128/JVI.01708-08.
    Full Text Link to Item
  - Sales, Ana Paula, Georgia D. Tomaras, and Thomas B. Kepler. “Improving peptide-MHC class I binding prediction for unbalanced datasets.” Bmc Bioinformatics 9 (September 19, 2008): 385. https://doi.org/10.1186/1471-2105-9-385.
    Full Text Link to Item
  - Keele, Brandon F., Elena E. Giorgi, Jesus F. Salazar-Gonzalez, Julie M. Decker, Kimmy T. Pham, Maria G. Salazar, Chuanxi Sun, et al. “Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection.” Proc Natl Acad Sci U S A 105, no. 21 (May 27, 2008): 7552–57. https://doi.org/10.1073/pnas.0802203105.
    Full Text Link to Item
  - Alam, S Munir, Richard M. Scearce, Robert J. Parks, Kelly Plonk, Steven G. Plonk, Laura L. Sutherland, Miroslaw K. Gorny, et al. “Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection.” J Virol 82, no. 1 (January 2008): 115–25. https://doi.org/10.1128/JVI.00927-07.
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  - Cleghorn, Farley, Jean W. Pape, Mauro Schechter, Courtenay Bartholomew, Jorge Sanchez, Noreen Jack, Barbara J. Metch, et al. “Lessons from a multisite international trial in the Caribbean and South America of an HIV-1 Canarypox vaccine (ALVAC-HIV vCP1452) with or without boosting with MN rgp120.” J Acquir Immune Defic Syndr 46, no. 2 (October 1, 2007): 222–30. https://doi.org/10.1097/QAI.0b013e318149297d.
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  - Shen, Xiaoying, Christian M. Leutenegger, Kelly Stefano Cole, Niels C. Pedersen, and Ellen E. Sparger. “A feline immunodeficiency virus vif-deletion mutant remains attenuated upon infection of newborn kittens.” J Gen Virol 88, no. Pt 10 (October 2007): 2793–99. https://doi.org/10.1099/vir.0.83268-0.
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  - Russell, Nina D., Barney S. Graham, Michael C. Keefer, M Juliana McElrath, Steve G. Self, Kent J. Weinhold, David C. Montefiori, et al. “Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial.” J Acquir Immune Defic Syndr 44, no. 2 (February 1, 2007): 203–12. https://doi.org/10.1097/01.qai.0000248356.48501.ff.
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  - Goepfert, Paul A., Georgia D. Tomaras, Helen Horton, David Montefiori, Guido Ferrari, Mark Deers, Gerald Voss, et al. “Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteers.” Vaccine 25, no. 3 (January 5, 2007): 510–18. https://doi.org/10.1016/j.vaccine.2006.07.050.
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  - Overman, R Glenn, Anthony L. Llorens, Michael L. Greenberg, Mariano A. Garcia-Blanco, and Georgia D. Tomaras. “Initiation of human immunodeficiency virus type 1 (HIV-1) transcription is inhibited by noncytolytic CD8 suppression.” Open Virol J 1 (2007): 1–7. https://doi.org/10.2174/1874357900701010001.
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  - McFarland, Elizabeth J., Daniel C. Johnson, Petronella Muresan, Terence Fenton, Georgia D. Tomaras, James McNamara, Jennifer S. Read, et al. “HIV-1 vaccine induced immune responses in newborns of HIV-1 infected mothers.” Aids 20, no. 11 (July 13, 2006): 1481–89. https://doi.org/10.1097/01.aids.0000237363.33994.45.
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  - Tomaras, Georgia D., Xiaoying Shen, and Michael L. Greenberg. “Antibody responses and virus escape: implications for HIV-1 vaccine and therapeutic design.” Future Virology 1, no. 1 (January 2006): 79–88. https://doi.org/10.2217/17460794.1.1.79.
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  - Johnson, Daniel C., Elizabeth J. McFarland, Petronella Muresan, Terence Fenton, James McNamara, Jennifer S. Read, Elizabeth Hawkins, et al. “Safety and immunogenicity of an HIV-1 recombinant canarypox vaccine in newborns and infants of HIV-1-infected women.” J Infect Dis 192, no. 12 (December 15, 2005): 2129–33. https://doi.org/10.1086/498163.
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  - Goepfert, Paul A., Helen Horton, M Juliana McElrath, Sanjay Gurunathan, Guido Ferrari, Georgia D. Tomaras, David C. Montefiori, et al. “High-dose recombinant Canarypox vaccine expressing HIV-1 protein, in seronegative human subjects.” J Infect Dis 192, no. 7 (October 1, 2005): 1249–59. https://doi.org/10.1086/432915.
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  - Betts, Michael R., Barbara Exley, David A. Price, Anju Bansal, Zenaido Tres Camacho, Vanessa Teaberry, Sadie M. West, et al. “Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection.” Proc Natl Acad Sci U S A 102, no. 12 (March 22, 2005): 4512–17. https://doi.org/10.1073/pnas.0408773102.
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  - Kaplan, Susan S., Guido Ferrari, Terri Wrin, Nicholas S. Hellmann, Georgia D. Tomaras, Victoria E. Gryszowka, Susan A. Fiscus, Kent J. Weinhold, and Charles B. Hicks. “Longitudinal assessment of immune response and viral characteristics in HIV-infected patients with prolonged CD4(+)/viral load discordance.” Aids Res Hum Retroviruses 21, no. 1 (January 2005): 13–16. https://doi.org/10.1089/aid.2005.21.13.
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  - Blattner, William A., Kris Ann Oursler, Farley Cleghorn, Manhattan Charurat, Anne Sill, Courtenay Bartholomew, Noreen Jack, et al. “Rapid clearance of virus after acute HIV-1 infection: correlates of risk of AIDS.” J Infect Dis 189, no. 10 (May 15, 2004): 1793–1801. https://doi.org/10.1086/386306.
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  - Morris, Kevin V., Joanne Higgins, Xiaoyng Shen, Jonny T. Stine, and Niels C. Pedersen. “The effects of HHV-8 vMIP-II on SIVmac251 infection and replication competent and incompetent SIVmac239Delta3 vectors.” Virus Res 94, no. 2 (August 2003): 103–12. https://doi.org/10.1016/s0168-1702(03)00138-2.
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  - Sufka, Susan A., Guido Ferrari, Victoria E. Gryszowka, Terri Wrin, Susan A. Fiscus, Georgia D. Tomaras, Herman F. Staats, et al. “Prolonged CD4+ cell/virus load discordance during treatment with protease inhibitor-based highly active antiretroviral therapy: immune response and viral control.” J Infect Dis 187, no. 7 (April 1, 2003): 1027–37. https://doi.org/10.1086/368359.
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  - Tomaras, G. D., and M. L. Greenberg. “CD8+ T cell mediated noncytolytic inhibition of human immunodeficiency virus type I.” Front Biosci 6 (March 1, 2001): D575–98. https://doi.org/10.2741/tomaras.
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  - Tomaras, Georgia D., and Michael L. Greenberg. “Mechanisms for HIV-1 Entry: Current Strategies to Interfere with This Step.” Curr Infect Dis Rep 3, no. 1 (February 2001): 93–99. https://doi.org/10.1007/s11908-001-0064-x.
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  - Hu, Q., J. O. Trent, G. D. Tomaras, Z. Wang, J. L. Murray, S. M. Conolly, J. M. Navenot, A. P. Barry, M. L. Greenberg, and S. C. Peiper. “Identification of ENV determinants in V3 that influence the molecular anatomy of CCR5 utilization.” J Mol Biol 302, no. 2 (September 15, 2000): 359–75. https://doi.org/10.1006/jmbi.2000.4076.
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  - Tomaras, G. D., S. F. Lacey, C. B. McDanal, G. Ferrari, K. J. Weinhold, and M. L. Greenberg. “CD8+ T cell-mediated suppressive activity inhibits HIV-1 after virus entry with kinetics indicating effects on virus gene expression.” Proc Natl Acad Sci U S A 97, no. 7 (March 28, 2000): 3503–8. https://doi.org/10.1073/pnas.070521097.
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  - Tomaras, G. D., D. A. Foster, C. M. Burrer, and S. M. Taffet. “ETS transcription factors regulate an enhancer activity in the third intron of TNF-alpha.” Journal of Leukocyte Biology 66, no. 1 (July 1999): 183–93. https://doi.org/10.1002/jlb.66.1.183.
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  - Brown, M. C., G. D. Tomaras, M. P. Vincenti, and S. M. Taffet. “Two forms of NF-kappa B1 (p105/p50) in murine macrophages: differential regulation by lipopolysaccharide, interleukin-2, and interferon-gamma.” J Interferon Cytokine Res 17, no. 5 (May 1997): 295–306. https://doi.org/10.1089/jir.1997.17.295.
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  - Safrit, Jeffrey T., Georgia D. Tomaras, Tomáš Hanke, Allan C. deCamp, and Yegor Voronin. “The Landscape of Targeted Immune Responses in the HIV-1 Vaccine Field.” Aids Res Hum Retroviruses 32, no. 10–11 (n.d.): 944–46. https://doi.org/10.1089/AID.2016.0120.
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- Other Articles
  - Zhu, Z., H. R. Qin, W. Chen, Q. Zhao, X. Shen, R. Schutte, Y. Wang, et al. “Erratum to Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies [Journal of Virology, 85, 21, (2011) 11401-11408] DOI: 10.1128/JVI.05312-11.” Journal of Virology, December 1, 2013. https://doi.org/10.1128/JVI.02726-13.
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  - Frahm, M. A., G. D. Tomaras, and G. Ferrari. “Response to comment on "CD4 ⁺CD8 ⁺ T cells represent a significant portion of the anti-HIV T cell response to acute HIV infection".” Journal of Immunology, June 15, 2012. https://doi.org/10.4049/jimmunol.1290029.
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  - Shen, X., and G. D. Tomaras. “Erratum to: Alterations of the B-cell response by HIV-1 replication (Current HIV/AIDS Reports (2011) 8, (23-30) DOI: 10.1007/s11904-010-0064-2).” Current Hiv/Aids Reports, March 1, 2011. https://doi.org/10.1007/s11904-011-0072-x.
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  - Knechtle, S., G. Remuzzi, and R. M. Strieter. “Editorial introductions.” Current Opinion in Organ Transplantation, December 1, 2004.
- Conference Papers
  - Sui, Yongjun, George Lewis, Yichuan Wang, Kurt Berckmueller, Blake Frey, Amiran Dzutsev, Diego Vargas-Inchaustegui, et al. “Mucosal vaccine efficacy against intrarectal SHIV acquisition independent of anti-Env antibody.” In Journal of Medical Primatology, 48:299–299. WILEY, 2019.
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  - Stieh, D. J., F. Tomaka, C. A. Comeaux, S. Nijs, K. Callewaert, J. Hendriks, Z. Euler, et al. “ASCENT: Phase 2a, randomized, double-blind, placebo controlled study evaluating safety and immunogenicity of two HIV-1 prophylactic vaccine regimens comprising Ad26. Mos4. HIV and either clade C gp140 or bivalent gp140.” In Journal of the International Aids Society, 22:98–98. JOHN WILEY & SONS LTD, 2019.
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  - Asbach, Benedikt, Karen V. Kibler, Josef Köstler, Beatriz Perdiguero, Nicole L. Yates, Sherry Stanfield-Oakley, Georgia D. Tomaras, et al. “Priming with a Potent HIV-1 DNA Vaccine Frames the Quality of Immune Responses prior to a Poxvirus and Protein Boost.” In J Virol, Vol. 93, 2019. https://doi.org/10.1128/JVI.01529-18.
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  - Dennison, S Moses, Milite Abraha, Richard H. C. Huntwork, Kan Li, Dustin L. Mauldin, S Munir Alam, and Georgia D. Tomaras. “Breadth of Human Monoclonal Antibodies Isolated from RTS,S/AS01 Vaccinees Binding to Plasmodium falciparum Circumsporozoite Protein Antigens.” In Biophysical Journal, 116:480a-480a. Elsevier BV, 2019. https://doi.org/10.1016/j.bpj.2018.11.2592.
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  - Cohen, Kristen, Mookho Malahleha, Fatima Laher, Linda-Gail Bekker, Kathryn Mngadi, Brodie Daniels, Craig Innes, et al. “Increase in Env-specific Binding Antibody and CD4+T Cell-responses After Month 30 Boost of gp120/MF59 Delivered Alone or With ALVAC-HIV.” In Aids Research and Human Retroviruses, 34:90–90. MARY ANN LIEBERT, INC, 2018.
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  - Edupuganti, Srilatha, Stephen De Rosa, Yunda Huang, Xao Han, Mengshu Shao, Marnie Elizaga, Edith Swann, et al. “Immune Responses to PENNVAX-GP (R) HIV DNA Vaccine Plus IL-12 Are Equivalent or Superior When Delivered by Intradermal vs. Intramuscular Electroporation.” In Aids Research and Human Retroviruses, 34:45–45. MARY ANN LIEBERT, INC, 2018.
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  - Felber, Barbara, Shakti Singh, Antonio Valentin, Margherita Rosati, Eric Ramierz, Rami Doueiri, Xintao Hu, et al. “DNA and protein co-delivery vaccines using TLR-4-based adjuvants induce potent immune responses able to delay heterologous SIV acquisition.” In Journal of Medical Primatology, 47:313–313. WILEY, 2018.
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  - Fleming, Lamar Ballweber, Kristen W. Cohen, Aaron Seese, Rachael Nelson, Crystal Huynh, Austin Varni, Zoe Moodie, et al. “Expansion of VH1-2*02 Env-specific B Cells in a Non-neutralizing HIV-1 Env Vaccine Regimen.” In Aids Research and Human Retroviruses, 34:109–109. MARY ANN LIEBERT, INC, 2018.
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  - Goepfert, Paul, Martin Casapia, Marnie Elizaga, Yu Huang, Julia Hutter, Chenchen Yu, Kelly Seaton, et al. “HVTN114: A Phase 1 Trial to Evaluate Late Boosts With AIDSVAX B/E of Participants Previously Vaccinated With MVA/HIV62B in DNA/MVA or MVA Regimens.” In Aids Research and Human Retroviruses, 34:184–184. MARY ANN LIEBERT, INC, 2018.
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  - Hosseinipour, Mina, Craig Innes, Sarita Naidoo, Georgia Tomaras, Lynn Morris, Allan DeCamp, Barbara Metch, et al. “Co-administration of 3 Doses of DNA/Protein Improves Antibody Responses to a Prime-boost Approach, but Needle-free Injection of DNA Shows No Benefit.” In Aids Research and Human Retroviruses, 34:337–337. MARY ANN LIEBERT, INC, 2018.
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  - Moodie, Zoe, Craig Innes, Mina Hosseinipour, Sarita Naidoo, Linda-Gail Bekker, Fatima Laher, Nicole Grunenberg, et al. “DNA-prime Induces Higher Magnitude Humoral Responses Than ALVAC-prime in HIV Vaccine Regimens With the Same Protein Boost.” In Aids Research and Human Retroviruses, 34:17–17. MARY ANN LIEBERT, INC, 2018.
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  - Pollara, Justin, Dorothy I. Jones, Tori Huffman, Maria Dennis, Grace Li, Derrick Goodman, R Whitney Edwards, et al. “Bridging Vaccine-induced Antibody Responses in Rabbit and Rhesus Macaque Animal Models.” In Aids Research and Human Retroviruses, 34:129–129. MARY ANN LIEBERT, INC, 2018.
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  - Seaton, Kelly, Rohith Palli, Michelle Key, Jack Heptinstall, Caroline Brackett, Jonathan Fuchs, Susan Buchbinder, et al. “Impact of Vaccine Regimen on Vaccine-induced Antibody Durability.” In Aids Research and Human Retroviruses, 34:88–88. MARY ANN LIEBERT, INC, 2018.
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  - Shen, Xiaoying, Zoe Moodie, Arthur McMillan, Derrick Goodman, Nicole Yates, Rachel Spreng, Nicole Grunenberg, et al. “V1V2 IgG and Antibody Fc Effector Functions in a Subtype C ALVAC-HIV and Bivalent Subtype C gp120/MF59 HIV-1 Vaccine Trial in South Africa.” In Aids Research and Human Retroviruses, 34:17–17. MARY ANN LIEBERT, INC, 2018.
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  - Sparger, Ellen, William Chang, Jesse Deere, Hung Kieu, Diego Castillo, Shelley Blozis, Jeffrey Lifson, et al. “Impact of a TLR-5 Ligand as Adjuvant on Immunogenicity and Efficacy of a RhCMV-SIV Vaccine.” In Journal of Medical Primatology, 47:313–14. WILEY, 2018.
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  - Stieh, Daniel J., Katleen Callewaert, Michal Sarnecki, Jenny Hendriks, Steven Nijs, Zelda Euler, Hanneke Schuitemaker, et al. “Primary Analysis of TRAVERSE: A Phase 1/2a Study to Assess Safety/Tolerability and Immunogenicity of 2 Different Prime/Boost HIV Vaccine Regimens.” In Aids Research and Human Retroviruses, 34:18–18. MARY ANN LIEBERT, INC, 2018.
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  - Tomaras, Georgia D., David Montefiori, Kristen W. Cohen, Jack Heptinstall, Stephen C. De Rosa, Sheetal Sawant, Lindsey R. Baden, et al. “Tetravalent Janssen Mosaic Ad26/Protein HIV Vaccine Shows Increased Clade C Env-specific CD4+T-cell and Antibody Responses Versus Trivalent Vaccine.” In Aids Research and Human Retroviruses, 34:187–187. MARY ANN LIEBERT, INC, 2018.
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  - Vaccari, Monica, Slim Fourati, Shari Gordon, Massimiliano Bissa, Luca Schifanella, Monica Silva de Castro, Trinh Hung, et al. “Vaccine-induced Activation of Inflammasome in Classical Monocytes and Th2 Cell Responses Correlates With Decreased Risk of SIVmac251 Acquisition.” In Aids Research and Human Retroviruses, 34:73–73. MARY ANN LIEBERT, INC, 2018.
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  - Williams, LaTonya, Matthew Zirui Tay, Xiaoying Shen, Sheetal Sawant, Lindsay Dahora, Nicole Yates, David Easterhoff, et al. “Delayed and Repetitive Boosting of RV144 Vaccinees Improves Antiviral Immunity Associated With Correlates of HIV-1 Infection Risk.” In Aids Research and Human Retroviruses, 34:88–88. MARY ANN LIEBERT, INC, 2018.
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  - Wilson, Gregory, Benigno Rodriguez, Marnie Elizaga, Sue Li, Mary Allen, Ian Frank, Erika Thommes, et al. “Safety and Immunogenicity of a pDNA Clade B Env Prime, rVSV Clade C Env Boost HIV-1 Vaccination Regimen in a Phase 1 Clinical Trial.” In Aids Research and Human Retroviruses, 34:16–16. MARY ANN LIEBERT, INC, 2018.
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  - Jones, A., R. Das, L. Wyatt, C. LaBranche, X. Shen, G. Tomaras, D. Montefiori, et al. “Oral MVA/protein HIV vaccination with a needle-free injector induces robust systemic and mucosal antibody responses in rhesus macaques.” In Journal of the International Aids Society, 21:2–2. JOHN WILEY & SONS LTD, 2018.
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  - Tomaka, F., D. Stieh, D. Barouch, M. Robb, N. Michael, G. Tomaras, G. Alter, et al. “Long-term data from APPROACH: phase 1/2a randomized, double-blind, placebo-controlled study evaluating safety/tolerability and immunogenicity of vaccine regimens using combinations of Ad26.Mos.HIV, MVA-mosaic and gp140 envelope protein.” In Journal of the International Aids Society, 21:2–3. JOHN WILEY & SONS LTD, 2018.
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  - Schneider, Jeffrey, Arangassery Bastian, Chiara Orlandi, Shaunna Shen, Judith Lucas, Vicki Ashley, Neil Kelleher, et al. “Mucin-binding IgG: Characterizing a novel antibody effector function and discovery of a new Fc receptor.” In Journal of Medical Primatology, 46:171–72. WILEY, 2017.
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  - Buchbinder, Susan, Nicole Grunenberg, Brittany Sanchez, Kelly Seaton, Guido Ferrari, M Anthony Moody, Nicole Frahm, et al. “DNA/MVA HIV Vaccine Producing Virus-like Particles (VLPs) Is Well-tolerated and Induces Durable Functional Antibodies (Abs) in HVTN 094.” In Aids Research and Human Retroviruses, 32:99–99. MARY ANN LIEBERT, INC, 2016.
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  - Felber, Barbara K., Antonio Valentin, Eric Ramirez Salazar, Rami Doueiri, Margherita Rosati, Xintao Hu, Candido Alicea, et al. “DNA and Protein Co-delivery Vaccines Using TLR-4-based Adjuvants Induce Potent Immune Responses Able to Delay Heterologous SIV Acquisition.” In Aids Research and Human Retroviruses, 32:67–67. MARY ANN LIEBERT, INC, 2016.
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  - Huang, Ying, Georgia Tomaras, Erica Andersen-Nissen, One Dintwe, Lynn Morris, Nicole Grunenberg, Abby Issacs, et al. “The Relationship between Immune Responses to Tetanus Vaccine, Hepatitis B Vaccine and a Pox-protein HIV Vaccine Regimen.” In Aids Research and Human Retroviruses, 32:76–76. MARY ANN LIEBERT, INC, 2016.
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  - Pala, Pietro, Jonathan Levin, Annet Nanvubya, Freddie Kibengo, Annemarie Namuniina, Paul Kitandwe, Jennifer Serwanga, et al. “EV06 Trial: Modulation of the Immunogenicity of the DNA-HIV-PT123 and AIDSVAX (R) B/E combination HIV vaccine in adult Ugandans by S. mansoni Infection.” In Aids Research and Human Retroviruses, 32:110–110. MARY ANN LIEBERT, INC, 2016.
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  - Pantaleo, Giuseppe, Holly Janes, Georgia Tomaras, David Montefiori, Nicole Frahm, Shannon Grant, Pierre-Alexandre Bart, et al. “Comparing Different Priming Strategies to Optimize HIV Vaccine Antibody Responses: Results from HVTN 096/EV04 (NCT01799954).” In Aids Research and Human Retroviruses, 32:68–68. MARY ANN LIEBERT, INC, 2016.
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  - Parks, Christopher, Maoli Yuan, John Coleman, Joanne Destefano, Xinsheng Zhang, Nicole Yates, Dan Barouch, et al. “Protection from Rectal SHIV Infection Induced by Mucosal Vaccination with a Replication-competent VSV-HIV Chimera Delivering Env Trimers.” In Aids Research and Human Retroviruses, 32:18–18. MARY ANN LIEBERT, INC, 2016.
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  - Schneider, Jeffrey, Arangassery Rosemary Bastian, Chiara Orlandi, Shaunna Shen, Judith Lucas, Vicki Ashley, Archer Smith, et al. “Mucin-binding IgG: Characterizing a Novel Antibody Effector Function and Discovery of a New Fc Receptor.” In Aids Research and Human Retroviruses, 32:112–112. MARY ANN LIEBERT, INC, 2016.
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  - Shen, Xiaoying, Rahul Basu, Suefen Kwa, Celia Labranche, David Beaumont, Guido Ferrari, Linda Wyatt, et al. “MVA-expressed gp140 Boosts More Durable V1/V2 and gp120 Antibody Responses than gp120 Protein in Alum.” In Aids Research and Human Retroviruses, 32:59–59. MARY ANN LIEBERT, INC, 2016.
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  - Tomaras, Georgia. “Overview of Humoral and Cellular Immune Responses to HIV Vaccination.” In Aids Research and Human Retroviruses, 32:14–14. MARY ANN LIEBERT, INC, 2016.
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  - Bekker, L. -. G., F. Laher, Z. Moodie, G. Tomaras, N. Grunenberg, M. Allen, B. Daniels, et al. “Meeting the "Go'' criteria: immunogenicity from HVTN100, a phase 1/2 randomized, double blind, placebo-controlled trial of clade C ALVAC-(R) (vCP2438) and Bivalent Subtype C gp120/MF59 (R) in HIV-uninfected South African adults.” In Journal of the International Aids Society, Vol. 19. JOHN WILEY & SONS LTD, 2016.
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  - Schmitz, Frank, Sarah Gerdts, Britta Flach, Miranda Moore, Jonathan Perkins, Harlan Robins, Alan Aderem, et al. “D-107 Vaccination establishes CXCR5+PD1+CD4+ peripheral blood germinal center T follicular helper cell relatives in humans.” In Jaids Journal of Acquired Immune Deficiency Syndromes, 71:55–55. Ovid Technologies (Wolters Kluwer Health), 2016. https://doi.org/10.1097/01.qai.0000479555.59732.37.
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  - Valentin, Antonio, Jinyao Li, Rashmi Jalah, Vainav Patel, Margherita Rosati, Viraj Kulkarni, Candido Alicea, et al. “DNA AND PROTEIN CO-IMMUNIZATION IMPROVES THE MAGNITUDE, LONGEVITY, AND MUCOSAL DISSEMINATION OF IMMUNE RESPONSES.” In Journal of Medical Primatology, 44:341–341. WILEY-BLACKWELL, 2015.
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  - Prentice, Heather, Georgia Tomaras, Daniel Geraghty, Richard Apps, Youyi Fong, Philip Ehrenberg, Morgane Rolland, et al. “HIV-1-specific IgG antibody levels correlate with the presence of a specific HLA class II allele to impact acquisition and vaccine efficacy.” In Journal of the International Aids Society, Vol. 18. JOHN WILEY & SONS LTD, 2015. https://doi.org/10.7448/IAS.18.5.20541.
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  - Pavlakis, George, Antonio Valentin, Jinyao Li, Rashmi Jalah, Vainav Patel, Margherita Rosati, Viraj Kulkarni, et al. “A-112 DNA and Protein Co-immunization Improves the Magnitude, Longevity, and mucosal dissemination of Immune Responses.” In Jaids Journal of Acquired Immune Deficiency Syndromes, 67:42–42. Ovid Technologies (Wolters Kluwer Health), 2014. https://doi.org/10.1097/01.qai.0000456064.93858.a1.
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  - De Rosa, Stephen, Nicole Frahm, Gabriela Diaz, Paul Newling, Daryl Morris, Cecilia Morgan, Barney Graham, et al. “No Increase in Activated T Cells and Limited Increase in Adenovirus-specific T Cells in Colon and Rectal Mucosa Following HIV-1 DNA/rAd5 Immunization.” In Aids Research and Human Retroviruses, 30:A48–A48. Mary Ann Liebert Inc, 2014. https://doi.org/10.1089/aid.2014.5082a.abstract.
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  - Fouda, G., J. Pollara, E. McGuire, W. Rountree, G. Overman, G. Tegha, D. Kamwendo, et al. “Association of HIV-1 Env Antibody Responses with Postnatal Mother-to-Child Transmission of HIV-1 via Breastfeeding.” In Aids Res Hum Retroviruses, 30 Suppl 1:A99–100, 2014. https://doi.org/10.1089/aid.2014.5182c.abstract.
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  - Gray, Glenda E., Erica Andersen-Nissen, Nicole Grunenberg, Ying Huang, Surita Roux, Fatima Laher, Craig Innes, et al. “HVTN 097: Evaluation of the RV144 Vaccine Regimen in HIV Uninfected South African Adults.” In Aids Research and Human Retroviruses, 30:A33–34. Mary Ann Liebert Inc, 2014. https://doi.org/10.1089/aid.2014.5052a.abstract.
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  - Hay, Christine M., Gregory J. Wilson, Marnie Elizaga, Sue Li, Nidhi Kochar, Mary Allen, Magdalena Sobieszczyk, et al. “An HIV DNA Vaccine Delivered by Electroporation and Boosted by rVSV HIV-1 Gag Is Safe and Immunogenic in Healthy HIV-uninfected Adults.” In Aids Research and Human Retroviruses, 30:A17–A17. Mary Ann Liebert Inc, 2014. https://doi.org/10.1089/aid.2014.5019.abstract.
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  - Le Grand, Roger, Nathalie Nathalie Bosquet, Stefania Dispinseri, Leslie Gosse, Delphine Des Jardins, Shen Shen, Georgia Tomaras, et al. “Microbicide-vaccine Combination Provides Significant Protection against Vaginal SHIV-162P3 Challenge in Cynomolgous Monkeys.” In Aids Research and Human Retroviruses, 30:A26–A26. Mary Ann Liebert Inc, 2014. https://doi.org/10.1089/aid.2014.5037a.abstract.
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  - Liao, L. H., A. M. Trama, W. B. Williams, M. A. Moody, N. Vandergrift, G. D. Tomaras, D. J. Marshall, et al. “Role of Intestinal Microbiota in Shaping the B Cell Repertoire in HIV Infection and Env Vaccination.” In Aids Res Hum Retroviruses, 30 Suppl 1:A19, 2014. https://doi.org/10.1089/aid.2014.5023a.abstract.
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  - Moody, M. A., D. Easterhoff, T. C. Gurley, J. F. Whitesides, D. J. Marshall, A. Foulger, K. E. Lloyd, et al. “Induction of Antibodies with Long Variable Heavy Third Complementarity Determining Regions by Repetitive Boosting with AIDSVAX® B/E in RV144 Vaccinees.” In Aids Res Hum Retroviruses, 30 Suppl 1:A36, 2014. https://doi.org/10.1089/aid.2014.5057a.abstract.
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  - Pavlakis, G. N., J. Li, A. Valentin, R. Jalah, V. Patel, M. Rosati, V. Kulkarni, et al. “DNA and Protein Co-immunization Improves the Magnitude, Longevity, and Mucosal Dissemination of Immune Responses.” In Aids Res Hum Retroviruses, 30 Suppl 1:A63–64, 2014. https://doi.org/10.1089/aid.2014.5115.abstract.
    Full Text Link to Item
  - Pavlakis, George N., Rashmi Jalah, Jinyao Li, Antonio Valentin, Margherita Rosati, Vainav Patel, Viraj Kulkarni, et al. “OPTIMIZATION OF SYSTEMIC AND MUCOSAL IMMUNE RESPONSES TO SIV AND HIV-1 ANTIGENS USING DIFFERENT PROTOCOLS OF DNA AND PROTEIN IMMUNIZATION IN MACAQUES.” In Journal of Medical Primatology, 43:410–410. WILEY-BLACKWELL, 2014.
    Link to Item
  - Prentice, Heather, Daniel Geraghty, Georgia D. Tomaras, Youyi Fong, Wyatt Nelson, Gustavo Kijak, Susan Zolla-Pazner, et al. “Immune Correlates Identified in the RV144 Vaccine Efficacy Trial Impact HIV-1 Acquisition Only in the Presence of Certain HLA Class II Genes.” In Aids Research and Human Retroviruses, 30:A40–A40. Mary Ann Liebert Inc, 2014. https://doi.org/10.1089/aid.2014.5065.abstract.
    Full Text
  - Schifanella, Luca, Nicolo Binello, Monica Vaccari, Shari N. Gordon, Francesca Caccuri, Matthew Blackburn, Melvin Doster, et al. “Plasmablast Phenotype and Mucosal Antibodies to V2 in Vaccine-induced Protection Against SIVmac251.” In Aids Research and Human Retroviruses, 30:A20–A20. Mary Ann Liebert Inc, 2014. https://doi.org/10.1089/aid.2014.5024.abstract.
    Full Text
  - Schneider, Jeffrey R., Maryam Shansab, Bronwyn Gunn, Shaunna Shen, Judith Lucas, Archer Smith, Neil Kelleher, et al. “Utilizing Mucin-tethered HIV IgG to Enhance HIV Vaccine Function.” In Aids Research and Human Retroviruses, 30:A154–A154. Mary Ann Liebert Inc, 2014. https://doi.org/10.1089/aid.2014.5315.abstract.
    Full Text
  - Shen, Xiaoying, William Williams, Nicole Yates, Joe Francica, Keith Reimann, David Montefiori, Julie McElrath, Robert Seder, and Georgia Tomaras. “HIV ENV-SPECIFIC IGG3 RESPONSES ARE DIFFERENTIALLY ELICITED IN NONHUMAN PRIMATE BY ENV VACCINES WITH DIFFERENT ADJUVANTS.” In Journal of Medical Primatology, 43:421–421. WILEY-BLACKWELL, 2014.
    Link to Item
  - Vaccari, M., S. N. Gordon, S. Fourati, L. Schifanella, M. Cameron, B. F. Keele, X. Shen, et al. “Adjuvant Dependent Mucosal V2 Responses and RAS Activation in Vaccine Induced Protection from SIVmac251 Acquisition.” In Aids Res Hum Retroviruses, 30 Suppl 1:A64–65, 2014. https://doi.org/10.1089/aid.2014.5117.abstract.
    Full Text Link to Item
  - Archary, D., K. Seaton, N. L. Yates, L. Werner, P. J. Bergin, L. J. Liebenberg, N. Samsunder, et al. “HIV-1 Specific Binding Antibody Titres in Blood Predict Detection in the Female Genital Tract in Women Who Became Infected in the CAPRISA 004 Microbicide.” In Aids Research and Human Retroviruses, 29:A101–A101. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Blasi, M., D. Negri, S. Santra, R. Parks, X. Shen, G. Tomaras, S. Permar, et al. “A Single Immunization with Integrase Defective Lentiviral Vector Expressing gp140 Induces Persistent and Functional Immune Response in Rhesus Monkeys.” In Aids Research and Human Retroviruses, 29:A161–A161. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Caskey, M., C. Trumpfheller, S. Schlesinger, S. Pollak, L. Sinnenberg, J. Pring, A. Hurley, et al. “In Vivo Targeting of HIV Gag to Dendritic Cells Given with Poly ICLC Is Safe and Induces Durable CD4 T Cell and B Cell Responses in Healthy Volunteers.” In Aids Research and Human Retroviruses, 29:A65–A65. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Fouda, G. G., C. K. Cunningham, E. J. McFarland, W. Borkowsky, P. Muresan, B. E. Liebl, H. Liao, et al. “HIV-1 gp120 Vaccination Elicits a Robust and Durable Anti-V1/V2 IgG Response and Yet No HIV-1 Env-Specific IgA Response in HIV-Exposed Infants.” In Aids Research and Human Retroviruses, 29:A13–14, 2013.
    Link to Item
  - Fouts, T. R., I. Prado, K. Bobb, R. Xu, M. Egan, G. Tomaras, D. Montefiori, G. Lewis, A. DeVico, and J. Eldridge. “Rhesus Full Length Single Chain (rhFLSC) Protects Rhesus Macaques from Heterologous Intrarectal Challenge with Multiple Low Doses of SHIV162P3.” In Aids Research and Human Retroviruses, 29:A40–A40. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Gordon, S. N., M. Vaccari, M. N. Doster, N. P. Liyanage, P. Pegu, L. Schifanella, F. Caccuri, et al. “Priming with Adenovirus26 Vaccines Affects ALVAC-SIV/gp120 Vaccine Efficacy Tested in a SIVmac251 Challenge Model Performed One-Month Post-Vaccination.” In Aids Research and Human Retroviruses, 29:A39–A39. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Hammer, S., M. Sobieszczyk, H. Janes, P. Gilbert, S. Karuna, D. Grove, S. Ramirez, et al. “HVTN 505: Efficacy of a Multi-Gene DNA Prime/Recombinant Adeno 5 (rAd5) Vector Boost Vaccine in Men & Transgender Women (TGW) Who Have Sex with Men.” In Aids Research and Human Retroviruses, 29:A172–A172. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Heeney, J. L., B. Jacobs, M. Esteban, R. Wagner, K. Foulds, M. Roederer, S. Self, et al. “Increased HIV-1 Immunogenicity of Replication Competent NYVAC.” In Aids Research and Human Retroviruses, 29:A160–A160. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Li, S. S., P. B. Gilbert, G. D. Tomaras, G. Kijak, G. Ferrari, R. Thomas, S. Zolla-Pazner, et al. “Association of Fc gamma RIIC Polymorphism with Vaccine Efficacy and Correlates of HIV-1 Infection Risk in RV144.” In Aids Research and Human Retroviruses, 29:A178–79. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Liyanage, N. P., S. N. Gordon, M. Vaccari, P. Pegu, M. N. Doster, G. D. Tomaras, D. Venzon, et al. “Alum and MF59, in Combination with ALVAC-SIV and Gp120 Vaccines Recruit Functionally Different NK Cells to the Gut of Vaccinated Rhesus Macaque.” In Aids Research and Human Retroviruses, 29:A100–A100. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Morris, L., N. N. Mkhize, T. Hermanus, E. Chung, A. Sato, S. Grant, N. Gu, et al. “Boosting Antibody Responses with gp140 Protein Two Years After DNA/MVA Priming: Results from the HVTN 073E Phase I Vaccine Trial.” In Aids Research and Human Retroviruses, 29:A171–A171. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Nabi, R., Q. Wei, Z. Moldoveanu, E. T. Golub, A. L. Landay, G. D. Tomaras, J. Mestecky, and P. A. Kozlowski. “Systemic IgG and IgA Responses to gp70V1V2 and C1 in HIV-Infected Elite Controllers Versus Controllers and Noncontrollers on HAART.” In Aids Research and Human Retroviruses, 29:A62–A62. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Pavlakis, G. N., R. Jalah, J. Li, A. Valentin, M. Rosati, V. Patel, V. Kulkarni, et al. “Optimization of Systemic and Mucosal Immune Responses to SIV and HIV-1 Antigens Using Different Protocols of DNA and Protein Immunization in Macaques.” In Aids Research and Human Retroviruses, 29:A19–A19. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Pollara, J., M. Bonsignori, M. Moody, S. Alam, K. Hwang, T. C. Gurley, D. M. Kozink, et al. “Heterogeneity of Anti-V2 ADCC Ab Responses and Implications for Vaccine Development.” In Aids Research and Human Retroviruses, 29:A41–A41. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Prentice, H., D. E. Geraghty, G. D. Tomaras, Y. Fong, W. Nelson, G. H. Kijak, S. Zolla-Pazner, et al. “HLA Class II Genes Interact with the Immune Correlates from the RV144 Vaccine Efficacy Trial and Impact HIV-1 Acquisition.” In Aids Research and Human Retroviruses, 29:A178–A178. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Rolland, M., P. T. Edlefsen, R. Gottardo, D. C. Montefiori, S. Zolla-Pazner, A. Moody, L. H. Liao, et al. “Genetic and Immunological Evidence for a Role of Env-V3 Antibodies in the RV144 Trial.” In Aids Research and Human Retroviruses, 29:A168–A168. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Schifanella, L., S. Gordon, M. Vaccari, N. Binello, F. Caccuri, M. Blackburn, C. Fenizia, et al. “MF59 and ALUM, in Combination with an ALVAC-SIV/gp120 Vaccine, Induce Plasmablasts that Differ in the Expression of Homing Markers.” In Aids Research and Human Retroviruses, 29:A13–A13. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Seaton, K., N. Yates, W. Williams, L. Liao, A. deCamp, Y. Fong, D. Montefiori, et al. “Human HIV-1 Vaccine Induced Antibody Durability and Env IgG3 Responses.” In Aids Research and Human Retroviruses, 29:A187–A187. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Shen, X., R. Howington, H. Park, S. Sadagopal, S. Kwa, A. Cope, S. Ding, et al. “Vaccine Induced Epitope Specific Antibodies to the SIV Envelope Are Distinct from Those Induced to the HIV-1 Envelope.” In Aids Research and Human Retroviruses, 29:A10–11. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Trama, A. M., H. Liao, F. H. Jaeger, S. M. Alam, K. Wiehe, T. L. Jeffries, A. Foulger, et al. “Intestinal Commensal Bacteria Shape the Pre-transmission Antibody Repertoire to HIV-1 Infection.” In Aids Research and Human Retroviruses, 29:A105–A105. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Vaccari, M., S. N. Gordon, M. Doster, N. Liynage, P. Pegu, L. Schifanella, B. F. Keele, et al. “Protection from SIVmac251 Acquisition by an ALVAC/SIV/gp120 Regimen Is Not Improved by the Increase of Anti-Envelope Antibodies and T Cell Responses.” In Aids Research and Human Retroviruses, 29:A34–A34. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Wiehe, K., D. Easterhoff, K. Luo, W. Williams, N. Vandergrift, E. Lloyd, C. Stolarchuk, et al. “Phylogenetic Conservation of a Dominant Antibody Light Chain HIV Env V2 Binding Motif in Human and rhesus Macaque Antibodies.” In Aids Research and Human Retroviruses, 29:A168–A168. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Williams, W. B., K. Jones, P. Liu, A. M. Trama, K. Seaton, M. A. Moody, N. Vandergrift, et al. “Antibody Repertoire Induced by the Multiclade (Env A, B, C) HIV-1 DNA Prime, rAd5 Boost VRC Vaccine.” In Aids Research and Human Retroviruses, 29:A9–A9. MARY ANN LIEBERT, INC, 2013.
    Link to Item
  - Pavlakis, George N., Rashmi Jalah, Antonio Valentin, Margherita Rosati, Vainav Patel, Viraj Kulkarni, Candido Alicea, et al. “Comparison of systemic and mucosal responses after DNA and protein co-immunization.” In Jaids Journal of Acquired Immune Deficiency Syndromes, 62:56–56. LIPPINCOTT WILLIAMS & WILKINS, 2013.
    Link to Item
  - Tomaras, Georgia D. “HIV-1 Vaccine Elicited IgA and IgG Antibody Specificities.” In Jaids Journal of Acquired Immune Deficiency Syndromes, 62:52–52. LIPPINCOTT WILLIAMS & WILKINS, 2013.
    Link to Item
  - Blackinton, J., M. Thompson, N. Mukherjee, S. Freel, G. Tomaras, and J. Keene. “Integration of global techniques to implicate post-transcriptional regulation in HIV infection.” In Journal of the International Aids Society, 15:23–23. JOHN WILEY & SONS LTD, 2012.
    Link to Item
  - Amos, J. D., A. B. Wilks, G. G. Fouda, S. D. Smith, G. R. Overman, K. Beck, M. A. Moody, G. D. Tomaras, and S. R. Permar. “Strong SIV gp120-specific IgG/IgA responses in milk of African green monkeys may contribute to the rarity of postnatal transmission in this species.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p198.
    Full Text
  - Caskey, M., C. Trumpfheller, S. Pollak, L. Sinnenberg, A. Hurley, J. Pring, I. Shimeliovich, et al. “In vivo targeting of HIV gag to dendritic cells in combination with poly ICLC is safe and immunogenic in healthy volunteers.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o51.
    Full Text
  - Fuchs, J. D., C. Morgan, P. Bart, N. Kochar, N. Frahm, E. Swann, P. Gilbert, et al. “DNA and recombinant adenovirus serotype 35 and 5 preventive HIV-1 vaccines with Env A inserts elicit cross-clade binding and V1V2 antibodies.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p136.
    Full Text
  - Goepfert, P., M. Elizaga, D. Montefiori, J. Hural, S. DeRosa, G. Tomaras, K. Seaton, et al. “Phase 2a safety and immunogenicity testing of DNA and recombinant modified vaccinia ankara virus vaccines expressing virus-like particles.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o56.
    Full Text
  - Hertz, T., A. Gartland, H. Janes, S. Li, Y. Fong, G. D. Tomaras, D. Morris, et al. “T-cell based sieve analysis ties HLA A*02 to vaccine efficacy and IgA-C1 immune correlate in RV144 Thai trial.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o61.
    Full Text
  - Liao, L., M. Bonsignori, K. Hwang, A. M. Moody, R. Park, S. Crawford, H. Chen, et al. “Design of an HIV Env antigen that binds with high affinity to antibodies against linear, conformational and broadly neutralizing epitopes within V1/V2.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o31.
    Full Text
  - Montefiori, D. C., Y. Huang, S. Karuna, M. Allen, N. Kochar, S. Chappuis, J. Gaillard, et al. “rAd5/NYVAC-B is superior to NYVAC-B/rAd5 and is dependent on rAd5 dose for neutralizing antibody responses against HIV-1.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p132.
    Full Text
  - Moody, M., A. M. Trama, M. Bonsignori, C. Tsao, M. S. Drinker, T. C. Gurley, J. D. Amos, et al. “Antibody lineages with evidence of somatic hypermutation persisting for >4 years in a South African subject with broad neutralizing activity.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p85.
    Full Text
  - Moody, M., M. S. Drinker, T. C. Gurley, J. D. Amos, J. A. Eudailey, L. C. Armand, R. Parks, et al. “Isolation of a clonal lineage of IgA broadly neutralizing antibodies from a chronically infected Tanzanian subject.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o35.
    Full Text
  - Pollara, J., M. Bonsignori, M. Moody, M. Alam, H. Liao, K. Hwang, J. Pickeral, et al. “Vaccine-induced ADCC-mediating antibodies target unique and overlapping envelope epitopes.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o39.
    Full Text
  - Spearman, P., G. Tomaras, D. Montefiori, Y. Huang, H. Ahmed, M. Elizaga, J. Hural, et al. “Rapid development of cross-clade neutralizing antibody responses after clade B gp120/gp140 protein priming and clade c gp140 protein boosting.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p137.
    Full Text
  - Trama, A. M., H. Liao, A. Foulger, D. J. Marshall, J. F. Whitesides, R. Parks, R. Meyerhoff, et al. “Lack of IgA envelope-reactive antibody producing cells in terminal ileum in early and chronic HIV-1 infection.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p201.
    Full Text
  - Williams, W. B., K. Jones, A. Krambrink, D. Grove, P. Liu, N. L. Yates, M. A. Moody, et al. “Multiple antibody specificities (gp41, V1V2, and V3) elicited in the phase II multiclade (A, B, C) HIV-1 DNA prime, rAd5 boost vaccine trial.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o55.
    Full Text
  - Billings, E. A., N. Karasavvas, M. S. de Souza, J. Currier, P. Pitisuttithum, J. Kaewkunwal, S. Nitayaphan, et al. “Surface Plasmon Resonance Analysis of Anti-gp120 V2-Specific IgG Antibodies Generated in the RV144 Thai Trial.” In Aids Research and Human Retroviruses, 27:A21–22. MARY ANN LIEBERT INC, 2011.
    Link to Item
  - Bonsignori, M., X. Wu, M. A. Moody, H. Liao, K. Hwang, J. A. Crump, S. H. Capiga, et al. “Isolation of CD4-Binding Site and V2/V3 Conformational (Quaternary) Broadly Neutralizing Antibodies from the Same HIV-1 Infected African Subject.” In Aids Research and Human Retroviruses, 27:A120–A120. MARY ANN LIEBERT INC, 2011.
    Link to Item
  - Ferrari, G., J. Pollara, D. Kozink, T. Harms, M. Drinker, S. Freel, M. A. Moody, et al. “Mapping of ADCC Activity: The A32 Conformational C1 Epitope is a Dominant Target for ADCC Antibodies in Chronically HIV-1 Infected Subjects.” In Aids Research and Human Retroviruses, 27:A66–A66. MARY ANN LIEBERT INC, 2011.
    Link to Item
  - Fouda, G., N. Yates, J. Pollara, G. Overman, T. Mahlokozera, A. Wilks, H. Kang, et al. “HIV Neutralization in Breast Milk Mirrors that of Plasma and Is Mainly Mediated by IgG Antibodies.” In Aids Research and Human Retroviruses, 27:A72–A72. MARY ANN LIEBERT INC, 2011.
    Link to Item
  - Frahm, N., D. P. Friedrich, P. Walsh, S. De Rosa, P. Spearman, S. Barnett, M. Keefer, et al. “A DNA Prime/Protein Boost Vaccine Leads to Higher B-Cell Responses than a Vector Prime/Protein Boost or DNA Prime/Vector Boost Regimens.” In Aids Research and Human Retroviruses, 27:A24–25. MARY ANN LIEBERT INC, 2011.
    Link to Item
  - Freel, S. A., R. A. Picking, G. Ferrari, C. Ochsenbauer, J. C. Kappes, J. Kirchherr, K. J. Weinhold, et al. “Ontogeny of CD8+T Cells in Acute HIV-1 that Inhibit Autologous and Heterologous Transmitted/Founder (T/F) Viruses.” In Aids Research and Human Retroviruses, 27:A13–A13. MARY ANN LIEBERT INC, 2011.
    Link to Item
  - Lynch, R. M., M. K. Louder, L. Tran, Z. Yang, G. Tomaras, M. Cohen, E. S. Gray, et al. “Detection of CD4-Binding Site Antibodies in Three HIV-1 Seroconverter Cohorts.” In Aids Research and Human Retroviruses, 27:A47–A47. MARY ANN LIEBERT INC, 2011.
    Link to Item
  - Pollara, J., L. Morris, N. Meguid, J. Pickeral, J. Hoxie, J. Kappes, C. Ochsenbauer, et al. “Ontogeny, Breadth, and Specificity of Circulating ADCC-Mediating Antibodies in HIV-1 Infected Individuals.” In Aids Research and Human Retroviruses, 27:A66–67. MARY ANN LIEBERT INC, 2011.
    Link to Item
  - Yang, H., H. Wu, S. A. Freel, H. Yan, X. Huang, X. Xu, J. Birks, G. D. Tomaras, A. McMichael, and L. Dorrell. “The CD8+T Cell Antiviral Inhibitory Activity Predicts the Rate of CD4+Cell Decline in Early HIV-1 Infection and Is Independent of Viral Subtype.” In Aids Research and Human Retroviruses, 27:A91–A91. MARY ANN LIEBERT INC, 2011.
    Link to Item
  - Zhu, Z., H. R. Qin, W. Chen, Q. Zhao, X. Shen, R. Schutte, Y. Wang, et al. “2F5-like Cross-Reactive HIV-1-Neutralizing Monoclonal Antibodies with Low Number of Somatic Mutations.” In Aids Research and Human Retroviruses, 27:A9–A9. MARY ANN LIEBERT INC, 2011.
    Link to Item
  - Alam, S., G. D. Tomaras, H. Liao, R. Parks, R. Meyerhoff, F. Jaeger, A. Foulger, et al. “Reverted unmutated ancestor 2F5 VH2-5 alleles differentially bind gp41 and bacterial proteins: a genetic basis for gp41 neutralizing B cell responses.” In Aids Research and Human Retroviruses, 26:A154–55. MARY ANN LIEBERT INC, 2010.
    Link to Item
  - Alam, S., S. M. Dennison, F. Jaeger, K. Anasti, L. Sutherland, C. Bowman, R. Parks, et al. “Induction of antibodies with specificity for gp41 neutralizing epitopes by membrane anchored gp41 immunogens.” In Aids Research and Human Retroviruses, 26:A64–A64. MARY ANN LIEBERT INC, 2010.
    Link to Item
  - Cirulli, E. T., D. Forthal, K. V. Shianna, J. Pandey, F. Sinangil, J. Fellay, K. Perez, et al. “Genome-Wide Significant Association of the GM 23 Allotype with gp120-Specific IgG2 Titers in an Efficacy Trial of AIDSVAX B/B.” In Aids Research and Human Retroviruses, 26:A70–A70. MARY ANN LIEBERT INC, 2010.
    Link to Item
  - Liao, H., X. Chen, S. Munshaw, R. Zhang, D. Marshall, J. Whitesides, A. Foulger, et al. “Early plasma B cell responses to transmitted HIV-1 are directed to envelope gp41 and originate by the activation of mutated B cell clones.” In Aids Research and Human Retroviruses, 26:A23–A23. MARY ANN LIEBERT INC, 2010.
    Link to Item
  - Liu, J., B. F. Keele, H. Liu, S. Keating, P. J. Norris, A. Carville, K. G. Mansfield, et al. “Low Dose Mucosal SIV Infection Restricts Early Replication Kinetics and Transmitted Virus Variants in Rhesus Monkeys.” In Aids Research and Human Retroviruses, 26:A29–A29. MARY ANN LIEBERT INC, 2010.
    Link to Item
  - Moody, M. A., J. D. Amos, T. C. Gurley, M. S. Drinker, K. D. Luney, D. J. Marshall, J. F. Whitesides, et al. “Isolation of Human Monoclonal Antibodies from HIV-Uninfected Subjects Immunized with gp120/NefTat/AS01B by Dual-Color Antigen-Specific B Cell Sorting.” In Aids Research and Human Retroviruses, 26:A15–A15. MARY ANN LIEBERT INC, 2010.
    Link to Item
  - Pollara, J., G. Landucci, C. Trac, C. White, N. Yates, J. Kappes, C. Ochsenbauer, et al. “Early Appearance of ADCC- and ADCVI-mediating Antibody Responses Against Autologous HIV-1 Transmitted/Founder Virus.” In Aids Research and Human Retroviruses, 26:A12–A12. MARY ANN LIEBERT INC, 2010.
    Link to Item
  - Pollara, J., L. Hart, J. Hoxie, J. Kappes, C. Ochsenbauer, L. Morris, K. Soderberg, et al. “High titers of cross-clade ADCC-mediating antibodies are detectable in plasma samples collected from individuals with broadly neutralizing antibodies.” In Aids Research and Human Retroviruses, 26:A20–21. MARY ANN LIEBERT INC, 2010.
    Link to Item
  - Tomaras, G., J. Binley, E. Gray, X. Shen, P. Moore, J. Decker, N. Yates, et al. “Epitope Specificities of Elite Neutralizing Sera from HIV-1-Infected Individuals.” In Aids Research and Human Retroviruses, 26:A24–A24. MARY ANN LIEBERT INC, 2010.
    Link to Item
  - Yates, N., X. Shen, P. Liu, S. Barnett, P. Spearman, S. Lu, G. Ferrari, et al. “Vaccine-Elicited IgG Subclasses and Functional Antibodies.” In Aids Research and Human Retroviruses, 26:A157–A157. MARY ANN LIEBERT INC, 2010.
    Link to Item
  - Zhu, Z., H. R. Qin, W. Chen, Q. Zhao, G. Fouda, R. Schutte, X. Shen, et al. “New broadly neutralizing human monoclonal antibodies targeting the 2F5 epitope.” In Aids Research and Human Retroviruses, 26:A14–15. MARY ANN LIEBERT INC, 2010.
    Link to Item
  - Liao, L., X. Chen, A. Dixon, S. Munshaw, M. Moody, R. Zhang, A. Nagel, et al. “P04-45. Characterization of the plasma cell repertoire in acute HIV-1 infection (AHI).” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-P73.
    Full Text
  - Munshaw, S., H. Liao, A. Dixon, X. Chen, A. Nagel, K. Derosa, R. Parks, et al. “S021-04 OA. A large-scale analysis of immunoglobulin sequences derived from plasmablasts/plasma cells in acute HIV-1 infection subjects.” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-O4.
    Full Text
  - Robinson, H. L., R. R. Amara, L. Lai, Y. Xu, S. De Rosa, O. Defawe, A. Sato, et al. “P19-58 LB. Comparison of the immunogenicity in humans and rhesus macaques of vaccines consisting of DNA priming and MVA boosting and MVA priming and boosting.” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-P422.
    Full Text
  - Shen, X., M. Dennison, F. Gao, D. C. Montefiori, L. Verkoczy, B. Haynes, M. Alam, and G. Tomaras. “OA021-04. HIV-1 gp41 envelope MPER mutation altered epitope conformation in lipid and increased sensitivity to 2F5 and 4E10 neutralizing antibodies.” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-O16.
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  - Yates, Nicole L., Judith Lucas, Rob Parks, Vicki C. Ashley, Glenn Overman, David C. Montefiori, Kent J. Weinhold, et al. “142 HIV Frequently Elicits Mucosal and Plasma Env-Specific IgA With a Rapid Initial Decline In Acute Infection.” In Jaids Journal of Acquired Immune Deficiency Syndromes, 51:1–1. Ovid Technologies (Wolters Kluwer Health), 2009. https://doi.org/10.1097/01.qai.0000351099.78513.42.
    Full Text
  - Bonsignori, M., M. A. Moody, R. J. Parks, T. M. Holl, G. Kelsoe, C. B. Hicks, N. Vandergrift, G. D. Tomaras, and B. F. Haynes. “P04-48. HIV-1 envelope induces memory B cell responses that correlate with plasma antibody levels after gp120 protein vaccination or chronic HIV-1 infection.” In Retrovirology, 6:P76–P76, 2009. https://doi.org/10.1186/1742-4690-6-s3-p76.
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  - Freel, S. A., P. K. Chattopadhyay, L. Lamoreaux, D. Zarkowsky, R. G. Overman, C. Ochsenbauer-Jambor, J. C. Kappes, et al. “S01-04 OA. Phenotypic analyses of CD8+ T cells that mediate virus inhibition from HIV-1 vaccinees and HIV-1+ virus controllers.” In Retrovirology, 6:O1, 2009.
  - Saunders, K. O., S. A. Freel, R. Overman, C. K. Cunningham, and G. D. Tomaras. “Inhibition of histone deacetylases modulates CD8+T-lymphocyte mediated virus suppression by HIV-1 viral controllers.” In Retrovirology, Vol. 6, 2009. https://doi.org/10.1186/1742-4690-6-S3-P269.
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  - Liu, P., N. L. Yates, B. F. Haynes, and G. D. Tomaras. “HIV-1 Immune Complexes are part of the Initial B cell Response in Acute HIV-1 infection.” In Aids Research and Human Retroviruses, 24:54–54. MARY ANN LIEBERT INC, 2008.
    Link to Item
  - Moody, M. A., M. K. Plonk, L. Fuller, H. Liao, S. Xia, M. S. Drinker, T. C. Gurley, et al. “Anti-lipid Human Monoclonal Antibodies Inhibit HIV-1 Infection of PBMC by Binding to Host Cells.” In Aids Research and Human Retroviruses, 24:13–13. MARY ANN LIEBERT INC, 2008.
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  - Shen, X., D. Montefiori, R. Parks, B. F. Haynes, and G. T. Tomaras. “2F5-Like Antibody Identified from an HIV-Infected Patient Concurrent with the Development of Autoimmune Antibodies.” In Aids Research and Human Retroviruses, 24:53–54. MARY ANN LIEBERT INC, 2008.
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  - Tomaras, G. D., and S. M. Taffet. “Transcriptional regulation of the promoter and enhancer regions of TNF-alpha by GABP and NF-kappa B.” In Journal of Leukocyte Biology, 25–25. FEDERATION AMER SOC EXP BIOL, 1997.
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Scholarly, Clinical, & Service Activities
Outreach & Engaged Scholarship
- Research for Prevention (R4P) Meeting. Chair and PI. 2018 - 2018 2018
- Organizer, HIV Vaccines/B Cell Meeting, Keystone Symposia, Keystone, CO, February 10-15. February 10, 2013 - February 15, 2013 2013
Service to the Profession

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Outreach & Engaged Scholarship

Service to the Profession