Geoffrey Steven Ginsburg
Professor of Medicine
Dr. Geoffrey S. Ginsburg's research interests are in the development of novel paradigms for developing and translating genomic information into medical practice and the integration of personalized medicine into health care.
Current Appointments & Affiliations
- Professor of Medicine, Medicine, Cardiology, Medicine 2005
- Director of Duke Center for Applied Genomics and Precision Medicine, Duke Center for Applied Genomics and Precision Medicine, Medicine 2014
- Professor in Pathology, Pathology, Clinical Science Departments 2006
- Professor in the School of Nursing, School of Nursing, Duke University 2016
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2004
Contact Information
- 101 Science Dr, Rm 2111, CIEMAS Bldg, Durham, NC 27708
- Duke Box 3382, Durham, NC 27710
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(919) 668-6210
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Google Scholar
- Background
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Education, Training, & Certifications
- Research Fellow in Cardiology, Medicine, Children's Hospital Boston 1987 - 1990
- Fellow in Cardiology, Medicine, Beth Israel Deaconess Medical Center 1987 - 1990
- Medical Resident, Medicine, Beth Israel Deaconess Medical Center 1984 - 1987
- M.D., Boston University 1984
- Ph.D., Boston University 1984
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Duke Appointment History
- Director of MEDx (Medicine and Engineering at Duke), Pratt School of Engineering, Duke University 2015 - 2018
- Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2014 - 2017
- Director of the IGSP Center for Genomic Medicine, Institutes and Centers, School of Medicine 2010 - 2014
- Instructor, Temporary in the Department of Medicine, Medicine, Cardiology, Medicine 2004 - 2005
- Recognition
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In the News
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MAR 16, 2021 Precision Medicine -
AUG 25, 2020 Duke Magnify -
JAN 9, 2020 -
AUG 21, 2019 Pratt School of Engineering -
JAN 10, 2019 Pratt School of Engineering -
NOV 1, 2018 Duke Health News -
FEB 22, 2017 Duke Health News -
DEC 15, 2015 -
OCT 21, 2015 U.S. News & World Report -
OCT 20, 2015 Nature -
OCT 11, 2015 -
AUG 10, 2015 -
JUN 20, 2014 Newsweek -
MAR 24, 2014 -
SEP 19, 2013 CBS News, AP -
SEP 18, 2013 -
JUL 7, 2013
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- Expertise
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Subject Headings
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Global Scholarship
- Research
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Selected Grants
- Duke University Program in Environmental Health awarded by National Institutes of Health 2013 - 2024
- Transplant Infectious Diseases Interdisciplinary Research Training Grant (TIDIRTG) awarded by National Institutes of Health 2018 - 2023
- Building and Deploying a Genomic-Medicine Risk Assessment Model for Diverse Primary Care Populations. awarded by National Institutes of Health 2018 - 2023
- The IGNITE II CC: Engagement, Coordination, Demonstration, and Dissemination awarded by National Institutes of Health 2018 - 2023
- Abbott Diagnostics Collaborative Sponsored Research Agreement awarded by Abbott Laboratories 2016 - 2022
- Preparing Genetic Counselors for Genomic Medicine Research awarded by National Institutes of Health 2017 - 2022
- Medical Scientist Training Program awarded by National Institutes of Health 1997 - 2022
- The Role of Junctophilin Type 2 in Cardiac Node Automaticity awarded by National Institutes of Health 2018 - 2022
- Postdoctoral Training in Genomic Medicine Research awarded by National Institutes of Health 2017 - 2022
- Multidisciplinary Heart and Vascular Diseases awarded by National Institutes of Health 1975 - 2022
- One-Carbon Metabolism Genetics Data Analyses awarded by KBRwyle 2020 - 2021
- Mapping Epigenetic Memory of Exposure New To Observe (MEMENTO) awarded by Defense Advanced Research Projects Agency 2019 - 2021
- Predicting prebiotic effects on human microbiota, behavior, and cognition. awarded by Office of Naval Research 2018 - 2021
- Interdisciplinary Training Program in Lung Disease awarded by National Institutes of Health 2009 - 2021
- Transfusion Medicine and Hematology awarded by National Institutes of Health 1975 - 2021
- Human-Based Sensor System for Presymptomatic Biological Exposure Detection awarded by Research Triangle Institute International 2019 - 2021
- Resilience Prediction to RSV Infection awarded by Sanofi US 2018 - 2020
- Study of Prognostic Biomarkers of Severe Systemic Bacterial Infection awarded by Genetech 2016 - 2020
- PREdicting contagion using Systems And GEnomic analysis (PRESAGE) awarded by Defense Advanced Research Projects Agency 2017 - 2020
- Novel host-based diagnostics of febrile illness in the warfighter awarded by Department of Defense 2016 - 2020
- MicroRNA Profiling to Characterize and Predict Posttraumatic Epilepsy following Traumatic Brain Injury awarded by Department of Defense 2018 - 2020
- Implementation, Adoption, and Utility of Family History in Diverse Care Settings awarded by National Institutes of Health 2013 - 2019
- Duke University Program in Environmental Health awarded by National Institute of Environmental Health Sciences 2013 - 2019
- Duke-UNC Clinical Hematology and Transfusion Research Career Development Program awarded by National Institutes of Health 2006 - 2019
- Development of Prognostic Platelet RNA Biomarkers To Tailor Antiplatelet Therapy awarded by National Institutes of Health 2013 - 2019
- Development and Application of Mathematical Methods for Tracking Biochronicity and Baseline Variation awarded by Defense Advanced Research Projects Agency 2016 - 2019
- Impact of Personal Genomic Testing on Primary Care Physician Knowledge and Attitudes awarded by 23andMe, Inc 2017 - 2018
- Novel Dialysis-Like Therapeutics in Sepsis-induced Shock and Organ Failure awarded by Defense Advanced Research Projects Agency 2015 - 2018
- Genetics of Normal Human Variation: Implications for Disease awarded by National Institutes of Health 2013 - 2017
- Genetic Risk Testing & Health Coaching for T2D and CHD awarded by Air Force Office of Scientific Research 2013 - 2017
- Feasibility for Predicting Warfighter Health Using Transcriptional Markers on the MAP Platform awarded by Ibis Biosciences, Inc. 2016
- Baseline Bio-molecular Models to Predict Infectious Disease Susceptibility awarded by Defense Advanced Research Projects Agency 2015 - 2016
- The Duke Multidisciplinary Training Program in Pediatric Lung Disease awarded by National Institutes of Health 2010 - 2016
- Plasmonics-Active SERS Nanoplatforms for In Vivo Diagnostics awarded by Defense Advanced Research Projects Agency 2012 - 2016
- Validation of the host transcription diagnostic for prediction of incipient respiratory viral infection awarded by Defense Advanced Research Projects Agency 2014 - 2016
- Pharmacogenetic Testing: Challenges of Clinical Integration awarded by National Institutes of Health 2007 - 2015
- Multidisciplinary Neonatal Training Grant awarded by National Institutes of Health 2010 - 2015
- Implications of Health and Genetic Literacy for Genomic Medicine awarded by National Institutes of Health 2010 - 2012
- CTSA UL awarded by National Institutes of Health 2006 - 2012
- Phase I Clinical Trial Describing the Pharmacogenomics of Aspirin awarded by National Institutes of Health 2009 - 2012
- Programs in Clinical Effectiveness of Cancer Pharmacogenomics awarded by National Institutes of Health 2009 - 2012
- Enabling Personalized Medicine through Clinical Decision Support awarded by National Institutes of Health 2008 - 2011
- Duke Clinical and Translational Science Institute awarded by National Institutes of Health 2006 - 2011
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External Relationships
- AbbVie, Inc.
- Coprata, LLC
- Elsevier
- Fabric Genomics
- Global Genomic Medicine Collaborative
- Konica-Minolta
- MeTree&You
- Peer Medical
- Predigen, Inc.
- origin commercial advisor
- Publications & Artistic Works
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Selected Publications
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Books
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Ginsburg, G. S., E. L. Tsalik, H. F. Willard, and C. W. Woods. Genomic and precision medicine: Infectious and inflammatory disease, 2019. https://doi.org/10.1016/C2015-0-06902-7.Full Text
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Ginsburg, G. S., and H. F. Willard. Genomic and precision medicine: Cardiovascular disease: Third edition, 2017.
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David, S. P., H. F. Willard, and G. S. Ginsburg. Preface, 2017. https://doi.org/10.1016/B978-0-12-800685-6.00021-7.Full Text
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Ginsburg, G. S., and H. F. Willard. Genomic and Precision Medicine: Foundations, Translation, and Implementation: Third Edition, 2016.
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Ginsburg, G. G., and H. H. Willard. Essentials of Genomic and Personalized Medicine, 2010.
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Ginsburg, G. S., and H. F. Willard. Genomic and Personalized Medicine, Two-Vol Set, 2009. https://doi.org/10.1016/B978-0-12-369420-1.X0001-7.Full Text
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Academic Articles
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She, Xichen, Yaya Zhai, Ricardo Henao, Christopher W. Woods, Christopher Chiu, Geoffrey S. Ginsburg, Peter X. K. Song, and Alfred O. Hero. “Adaptive Multi-Channel Event Segmentation and Feature Extraction for Monitoring Health Outcomes.” Ieee Trans Biomed Eng 68, no. 8 (August 2021): 2377–88. https://doi.org/10.1109/TBME.2020.3038652.Full Text Link to Item
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Bylstra, Yasmin, Weng Khong Lim, Sylvia Kam, Koei Wan Tham, R Ryanne Wu, Jing Xian Teo, Sonia Davila, et al. “Correction to: Family history assessment significantly enhances delivery of precision medicine in the genomics era.” Genome Med 13, no. 1 (July 5, 2021): 109. https://doi.org/10.1186/s13073-021-00916-9.Full Text Link to Item
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Steinbrink, Julie M., Rachel A. Myers, Kaiyuan Hua, Melissa D. Johnson, Jessica L. Seidelman, Ephraim L. Tsalik, Ricardo Henao, et al. “The host transcriptional response to Candidemia is dominated by neutrophil activation and heme biosynthesis and supports novel diagnostic approaches.” Genome Med 13, no. 1 (July 5, 2021): 108. https://doi.org/10.1186/s13073-021-00924-9.Full Text Link to Item
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Ginsburg, Geoffrey S., Larisa H. Cavallari, Hrishikesh Chakraborty, Rhonda M. Cooper-DeHoff, Paul R. Dexter, Michael T. Eadon, Bart S. Ferket, et al. “Establishing the value of genomics in medicine: the IGNITE Pragmatic Trials Network.” Genet Med 23, no. 7 (July 2021): 1185–91. https://doi.org/10.1038/s41436-021-01118-9.Full Text Open Access Copy Link to Item
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Meyersohn, Nandini M., Thomas Mayrhofer, Kathleen E. Corey, Daniel O. Bittner, Pedro V. Staziaki, Balint Szilveszter, Travis Hallett, et al. “Association of Hepatic Steatosis With Major Adverse Cardiovascular Events, Independent of Coronary Artery Disease.” Clin Gastroenterol Hepatol 19, no. 7 (July 2021): 1480-1488.e14. https://doi.org/10.1016/j.cgh.2020.07.030.Full Text Link to Item
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Chen, Lingye, Bryan D. Kraft, Victor L. Roggli, Zachary R. Healy, Christopher W. Woods, Ephraim L. Tsalik, Geoffrey S. Ginsburg, et al. “Heparin-based blood purification attenuates organ injury in baboons with S. pneumoniae pneumonia.” Am J Physiol Lung Cell Mol Physiol, June 9, 2021. https://doi.org/10.1152/ajplung.00337.2020.Full Text Link to Item
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Wang, Liuyang, Thomas J. Balmat, Alejandro L. Antonia, Florica J. Constantine, Ricardo Henao, Thomas W. Burke, Andy Ingham, et al. “An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility.” Genome Med 13, no. 1 (May 17, 2021): 83. https://doi.org/10.1186/s13073-021-00904-z.Full Text Link to Item
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Tsalik, Ephraim L., Ricardo Henao, Jesse L. Montgomery, Jeff W. Nawrocki, Mert Aydin, Emily C. Lydon, Emily R. Ko, et al. “Discriminating Bacterial and Viral Infection Using a Rapid Host Gene Expression Test.” Crit Care Med, April 28, 2021. https://doi.org/10.1097/CCM.0000000000005085.Full Text Link to Item
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Kammerlander, Andreas A., Thomas Mayrhofer, Maros Ferencik, Neha J. Pagidipati, Julia Karady, Geoffrey S. Ginsburg, Michael T. Lu, et al. “Association of Metabolic Phenotypes With Coronary Artery Disease and Cardiovascular Events in Patients With Stable Chest Pain.” Diabetes Care 44, no. 4 (April 2021): 1038–45. https://doi.org/10.2337/dc20-1760.Full Text Link to Item
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Fung, Si Ming, R Ryanne Wu, Rachel A. Myers, Jasper Goh, Geoffrey S. Ginsburg, David Matchar, Lori A. Orlando, and Joanne Ngeow. “Clinical implementation of an oncology-specific family health history risk assessment tool.” Hered Cancer Clin Pract 19, no. 1 (March 20, 2021): 20. https://doi.org/10.1186/s13053-021-00177-y.Full Text Open Access Copy Link to Item
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McClain, Micah T., Florica J. Constantine, Bradly P. Nicholson, Marshall Nichols, Thomas W. Burke, Ricardo Henao, Daphne C. Jones, et al. “A blood-based host gene expression assay for early detection of respiratory viral infection: an index-cluster prospective cohort study.” Lancet Infect Dis 21, no. 3 (March 2021): 396–404. https://doi.org/10.1016/S1473-3099(20)30486-2.Full Text Open Access Copy Link to Item
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McClain, Micah T., Florica J. Constantine, Ricardo Henao, Yiling Liu, Ephraim L. Tsalik, Thomas W. Burke, Julie M. Steinbrink, et al. “Dysregulated transcriptional responses to SARS-CoV-2 in the periphery.” Nat Commun 12, no. 1 (February 17, 2021): 1079. https://doi.org/10.1038/s41467-021-21289-y.Full Text Open Access Copy Link to Item
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Infeld, Margaret, Kevin A. Friede, Tan Ru San, Holly J. Knickerbocker, Geoffrey S. Ginsburg, Thomas L. Ortel, and Deepak Voora. “Platelet reactivity in response to aspirin and ticagrelor in African-Americans and European-Americans.” J Thromb Thrombolysis 51, no. 2 (February 2021): 249–59. https://doi.org/10.1007/s11239-020-02327-w.Full Text Link to Item
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Mahle, Rachael E., Sunil Suchindran, Ricardo Henao, Julie M. Steinbrink, Thomas W. Burke, Micah T. McClain, Geoffrey S. Ginsburg, Christopher W. Woods, and Ephraim L. Tsalik. “Validation of a host gene expression test for bacterial/viral discrimination in immunocompromised hosts.” Clin Infect Dis, January 19, 2021. https://doi.org/10.1093/cid/ciab043.Full Text Link to Item
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Perakslis, Eric, and Geoffrey S. Ginsburg. “Digital Health-The Need to Assess Benefits, Risks, and Value.” Jama 325, no. 2 (January 12, 2021): 127–28. https://doi.org/10.1001/jama.2020.22919.Full Text Link to Item
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Bylstra, Yasmin, Weng Khong Lim, Sylvia Kam, Koei Wan Tham, R Ryanne Wu, Jing Xian Teo, Sonia Davila, et al. “Family history assessment significantly enhances delivery of precision medicine in the genomics era.” Genome Med 13, no. 1 (January 7, 2021): 3. https://doi.org/10.1186/s13073-020-00819-1.Full Text Link to Item
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McCarthy, Jeanette, George Patrinos, and Geoffrey Ginsburg. “Welcome to the 18th volume of Personalized Medicine.” Per Med 18, no. 1 (January 2021): 1–3. https://doi.org/10.2217/pme-2020-0176.Full Text Link to Item
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She, Xichen, Yaya Zhai, Ricardo Henao, Christopher W. Woods, Christopher Chiu, Geoffrey S. Ginsburg, Peter X. K. Song, and Alfred O Hero III. “Adaptive Multi-Channel Event Segmentation and Feature Extraction for Monitoring Health Outcomes.” Ieee Trans. Biomed. Eng. 68 (2021): 2377–88.
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Wang, Liuyang, Thomas J. Balmat, Alejandro L. Antonia, Florica J. Constantine, Ricardo Henao, Thomas W. Burke, Andy Ingham, et al. “An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility.” Medrxiv, December 22, 2020. https://doi.org/10.1101/2020.12.20.20248572.Full Text Link to Item
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Levy, Kenneth D., Kathryn Blake, Colette Fletcher-Hoppe, James Franciosi, Daisuke Goto, James K. Hicks, Ann M. Holmes, et al. “Correction: Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network.” Genet Med, December 7, 2020. https://doi.org/10.1038/s41436-020-01054-0.Full Text Link to Item
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Giroux, Nicholas S., Shengli Ding, Micah T. McClain, Thomas W. Burke, Elizabeth Petzold, Hong A. Chung, Grecia R. Palomino, et al. “Chromatin remodeling in peripheral blood cells reflects COVID-19 symptom severity.” Biorxiv, December 5, 2020. https://doi.org/10.1101/2020.12.04.412155.Full Text Open Access Copy Link to Item
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Manolio, Teri A., Carol J. Bult, Rex L. Chisholm, Patricia A. Deverka, Geoffrey S. Ginsburg, Madison Goldrich, Gail P. Jarvik, et al. “Genomic Medicine Year in Review: 2020.” Am J Hum Genet 107, no. 6 (December 3, 2020): 1007–10. https://doi.org/10.1016/j.ajhg.2020.11.005.Full Text Link to Item
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Orlando, Lori A., R Ryanne Wu, Rachel A. Myers, Joan Neuner, Catherine McCarty, Irina V. Haller, Melissa Harry, et al. “At the intersection of precision medicine and population health: an implementation-effectiveness study of family health history based systematic risk assessment in primary care.” Bmc Health Services Research 20, no. 1 (November 7, 2020): 1015. https://doi.org/10.1186/s12913-020-05868-1.Full Text
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Manolio, T. A., P. Goodhand, and G. Ginsburg. “The International Hundred Thousand Plus Cohort Consortium: integrating large-scale cohorts to address global scientific challenges.” The Lancet Digital Health 2, no. 11 (November 1, 2020): e567–68. https://doi.org/10.1016/S2589-7500(20)30242-9.Full Text
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Levy, Kenneth D., Kathryn Blake, Colette Fletcher-Hoppe, James Franciosi, Diasuke Goto, James K. Hicks, Ann M. Holmes, et al. “Correction: Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network.” Genet Med 22, no. 10 (October 2020): 1730. https://doi.org/10.1038/s41436-020-0911-5.Full Text Link to Item
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Belcher, Andrea, Geoffrey S. Ginsburg, and Robyn Ward. “Global approaches to genomic medicine implementation.” Sci Transl Med 12, no. 563 (September 30, 2020). https://doi.org/10.1126/scitranslmed.aax0911.Full Text Link to Item
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McClain, Micah T., Florica J. Constantine, Ricardo Henao, Yiling Liu, Ephraim L. Tsalik, Thomas W. Burke, Julie M. Steinbrink, et al. “Dysregulated transcriptional responses to SARS-CoV-2 in the periphery support novel diagnostic approaches.” Medrxiv, July 26, 2020. https://doi.org/10.1101/2020.07.20.20155507.Full Text Open Access Copy Link to Item
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Friede, Kevin A., Margaret M. Infeld, Ru San Tan, Holly J. Knickerbocker, Rachel A. Myers, Laura G. Dubois, J Will Thompson, et al. “Influence of Sex on Platelet Reactivity in Response to Aspirin.” J Am Heart Assoc 9, no. 14 (July 21, 2020): e014726. https://doi.org/10.1161/JAHA.119.014726.Full Text Link to Item
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Tillekeratne, L Gayani, Sunil Suchindran, Emily R. Ko, Elizabeth A. Petzold, Champica K. Bodinayake, Ajith Nagahawatte, Vasantha Devasiri, et al. “Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population.” Open Forum Infect Dis 7, no. 6 (June 2020): ofaa194. https://doi.org/10.1093/ofid/ofaa194.Full Text Open Access Copy Link to Item
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Wu, R Ryanne, Rehena Sultana, Yasmin Bylstra, Saumya Jamuar, Sonia Davila, Weng Khong Lim, Geoffrey S. Ginsburg, et al. “Evaluation of family health history collection methods impact on data and risk assessment outcomes.” Prev Med Rep 18 (June 2020): 101072. https://doi.org/10.1016/j.pmedr.2020.101072.Full Text Link to Item
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Haga, Susanne B., Ryan Shaw, Charles Kneifel, Sarah J. Bond, and Geoffrey S. Ginsburg. “Promoting Wellness Through Mobile Health Technology in a College Student Population: Protocol Development and Pilot Study.” Jmir Res Protoc 9, no. 4 (April 3, 2020): e16474. https://doi.org/10.2196/16474.Full Text Link to Item
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Arges, Kristine, Themistocles Assimes, Vikram Bajaj, Suresh Balu, Mustafa R. Bashir, Laura Beskow, Rosalia Blanco, et al. “The Project Baseline Health Study: a step towards a broader mission to map human health.” Npj Digit Med 3 (2020): 84. https://doi.org/10.1038/s41746-020-0290-y.Full Text Open Access Copy Link to Item
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Manolio, Teri A., Carol J. Bult, Rex L. Chisholm, Patricia A. Deverka, Geoffrey S. Ginsburg, Gail P. Jarvik, Howard L. McLeod, et al. “Genomic Medicine Year in Review: 2019.” Am J Hum Genet 105, no. 6 (December 5, 2019): 1072–75. https://doi.org/10.1016/j.ajhg.2019.11.006.Full Text Link to Item
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Ginsburg, Geoffrey S., Ebony Madden, and Philip E. Empey. “Affiliate network members as force amplifiers of genomic medicine research.” Per Med 16, no. 6 (November 2019): 431–33. https://doi.org/10.2217/pme-2019-0077.Full Text Link to Item
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Tsalik, Ephraim L., Ayeaye Khine, Abdossamad Talebpour, Alaleh Samiei, Vilcy Parmar, Thomas W. Burke, Micah T. Mcclain, et al. “Rapid, Sample-to-Answer Host Gene Expression Test to Diagnose Viral Infection.” Open Forum Infect Dis 6, no. 11 (November 2019): ofz466. https://doi.org/10.1093/ofid/ofz466.Full Text Open Access Copy Link to Item
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Lydon, Emily C., Ricardo Henao, Thomas W. Burke, Mert Aydin, Bradly P. Nicholson, Seth W. Glickman, Vance G. Fowler, et al. “Validation of a host response test to distinguish bacterial and viral respiratory infection.” Ebiomedicine 48 (October 2019): 453–61. https://doi.org/10.1016/j.ebiom.2019.09.040.Full Text Open Access Copy Link to Item
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Ginsburg, Geoffrey S., R Ryanne Wu, and Lori A. Orlando. “Family health history: underused for actionable risk assessment.” Lancet 394, no. 10198 (August 17, 2019): 596–603. https://doi.org/10.1016/S0140-6736(19)31275-9.Full Text Link to Item
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Manolio, Teri A., Robb Rowley, Marc S. Williams, Dan Roden, Geoffrey S. Ginsburg, Carol Bult, Rex L. Chisholm, et al. “Opportunities, resources, and techniques for implementing genomics in clinical care.” Lancet 394, no. 10197 (August 10, 2019): 511–20. https://doi.org/10.1016/S0140-6736(19)31140-7.Full Text Link to Item
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Sutton, Lynn, Lisa G. Berdan, Jean Bolte, Robert M. Califf, Geoffrey S. Ginsburg, Jennifer S. Li, Jonathan McCall, et al. “Facilitating translational team science: The project leader model.” J Clin Transl Sci 3, no. 4 (August 2019): 140–46. https://doi.org/10.1017/cts.2019.398.Full Text Link to Item
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Ginsburg, Geoffrey S., Carol R. Horowitz, and Lori A. Orlando. “What will it take to implement genomics in practice? Lessons from the IGNITE Network.” Per Med 16, no. 4 (July 2019): 259–61. https://doi.org/10.2217/pme-2019-0021.Full Text Link to Item
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Levy, Kenneth D., Kathryn Blake, Colette Fletcher-Hoppe, James Franciosi, Diasuke Goto, James K. Hicks, Ann M. Holmes, et al. “Correction: Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network.” Genet Med 21, no. 7 (July 2019): 1670. https://doi.org/10.1038/s41436-018-0280-5.Full Text Link to Item
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Zebrowski, Alexis M., Darcy E. Ellis, Frances K. Barg, Nina R. Sperber, Barbara A. Bernhardt, Joshua C. Denny, Paul R. Dexter, et al. “Qualitative study of system-level factors related to genomic implementation.” Genet Med 21, no. 7 (July 2019): 1534–40. https://doi.org/10.1038/s41436-018-0378-9.Full Text Link to Item
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Januzzi, James L., Sunil Suchindran, Adrian Coles, Maros Ferencik, Manesh R. Patel, Udo Hoffmann, Geoffrey S. Ginsburg, Pamela S. Douglas, and Pamela S. PROMISE Investigators. “High-Sensitivity Troponin I and Coronary Computed Tomography in Symptomatic Outpatients With Suspected CAD: Insights From the PROMISE Trial.” Jacc Cardiovasc Imaging 12, no. 6 (June 2019): 1047–55. https://doi.org/10.1016/j.jcmg.2018.01.021.Full Text Link to Item
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Haga, Susanne B., Esther Kim, Rachel A. Myers, and Geoffrey S. Ginsburg. “Primary Care Physicians' Knowledge, Attitudes, and Experience with Personal Genetic Testing.” J Pers Med 9, no. 2 (May 24, 2019). https://doi.org/10.3390/jpm9020029.Full Text Link to Item
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Januzzi, James L., Geoffrey S. Ginsburg, and Pamela S. Douglas. “Reply: hs-cTnI in Stable Chest Pain.” J Am Coll Cardiol 73, no. 16 (April 30, 2019): 2121–22. https://doi.org/10.1016/j.jacc.2019.02.050.Full Text Link to Item
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Ginsburg, Geoffrey S. “A Global Collaborative to Advance Genomic Medicine.” Am J Hum Genet 104, no. 3 (March 7, 2019): 407–9. https://doi.org/10.1016/j.ajhg.2019.02.010.Full Text Link to Item
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Levy, Kenneth D., Kathryn Blake, Colette Fletcher-Hoppe, James Franciosi, Daisuke Goto, James K. Hicks, Ann M. Holmes, et al. “Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network.” Genet Med 21, no. 3 (March 2019): 743–47. https://doi.org/10.1038/s41436-018-0080-y.Full Text Link to Item
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Wu, R Ryanne, Rachel A. Myers, Adam H. Buchanan, David Dimmock, Kimberly G. Fulda, Irina V. Haller, Susanne B. Haga, et al. “Effect of Sociodemographic Factors on Uptake of a Patient-Facing Information Technology Family Health History Risk Assessment Platform.” Appl Clin Inform 10, no. 2 (March 2019): 180–88. https://doi.org/10.1055/s-0039-1679926.Full Text Link to Item
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Wu, R Ryanne, Rachel A. Myers, Nina Sperber, Corrine I. Voils, Joan Neuner, Catherine A. McCarty, Irina V. Haller, et al. “Implementation, adoption, and utility of family health history risk assessment in diverse care settings: evaluating implementation processes and impact with an implementation framework.” Genet Med 21, no. 2 (February 2019): 331–38. https://doi.org/10.1038/s41436-018-0049-x.Full Text Link to Item
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Januzzi, James L., Sunil Suchindran, Udo Hoffmann, Manesh R. Patel, Maros Ferencik, Adrian Coles, Jean-Claude Tardif, Geoffrey S. Ginsburg, Pamela S. Douglas, and Pamela S. PROMISE Investigators. “Single-Molecule hsTnI and Short-Term Risk in Stable Patients With Chest Pain.” J Am Coll Cardiol 73, no. 3 (January 29, 2019): 251–60. https://doi.org/10.1016/j.jacc.2018.10.065.Full Text Link to Item
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Limkakeng, Alexander T., Ricardo Henao, Deepak Voora, Thomas O’Connell, Michelle Griffin, Ephraim L. Tsalik, Svati Shah, Christopher W. Woods, and Geoffrey S. Ginsburg. “Pilot study of myocardial ischemia-induced metabolomic changes in emergency department patients undergoing stress testing.” Plos One 14, no. 2 (2019): e0211762. https://doi.org/10.1371/journal.pone.0211762.Full Text Open Access Copy Link to Item
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Lydon, Emily C., Charles Bullard, Mert Aydin, Olga M. Better, Anna Mazur, Bradly P. Nicholson, Emily R. Ko, et al. “A host gene expression approach for identifying triggers of asthma exacerbations.” Plos One 14, no. 4 (2019): e0214871. https://doi.org/10.1371/journal.pone.0214871.Full Text Open Access Copy Link to Item
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Makedonas, George, Satish Mehta, Alexander Choukèr, Richard J. Simpson, Gailen Marshall, Jordan S. Orange, Serena Aunon-Chancellor, et al. “Specific Immunologic Countermeasure Protocol for Deep-Space Exploration Missions.” Front Immunol 10 (2019): 2407. https://doi.org/10.3389/fimmu.2019.02407.Full Text Link to Item
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Fourati, Slim, Aarthi Talla, Mehrad Mahmoudian, Joshua G. Burkhart, Riku Klén, Ricardo Henao, Thomas Yu, et al. “A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection.” Nat Commun 9, no. 1 (October 24, 2018): 4418. https://doi.org/10.1038/s41467-018-06735-8.Full Text Open Access Copy Link to Item
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Bradley, Todd, Dimitra Peppa, Isabela Pedroza-Pacheco, Dapeng Li, Derek W. Cain, Ricardo Henao, Vaishnavi Venkat, et al. “RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.” Cell 175, no. 2 (October 4, 2018): 387-399.e17. https://doi.org/10.1016/j.cell.2018.08.064.Full Text Link to Item
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Ginsburg, Geoffrey S., Jeanette J. McCarthy, and George P. Patrinos. “A note from the editors.” Per Med 15, no. 4 (July 1, 2018): 237–38. https://doi.org/10.2217/pme-2018-0040.Full Text Link to Item
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Sweeney, Timothy E., Tej D. Azad, Michele Donato, Winston A. Haynes, Thanneer M. Perumal, Ricardo Henao, Jesús F. Bermejo-Martin, et al. “Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters.” Crit Care Med 46, no. 6 (June 2018): 915–25. https://doi.org/10.1097/CCM.0000000000003084.Full Text Link to Item
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Lu, Christine Y., Stephanie Loomer, Rachel Ceccarelli, Kathleen M. Mazor, James Sabin, Ellen Wright Clayton, Geoffrey S. Ginsburg, and Ann Chen Wu. “Insurance Coverage Policies for Pharmacogenomic and Multi-Gene Testing for Cancer.” J Pers Med 8, no. 2 (May 16, 2018). https://doi.org/10.3390/jpm8020019.Full Text Link to Item
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Ginsburg, Geoffrey S., and Kathryn A. Phillips. “Precision Medicine: From Science To Value.” Health Aff (Millwood) 37, no. 5 (May 2018): 694–701. https://doi.org/10.1377/hlthaff.2017.1624.Full Text Link to Item
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Volpi, Simona, Carol J. Bult, Rex L. Chisholm, Patricia A. Deverka, Geoffrey S. Ginsburg, Howard J. Jacob, Melpomeni Kasapi, et al. “Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects.” Clin Pharmacol Ther 103, no. 5 (May 2018): 778–86. https://doi.org/10.1002/cpt.1048.Full Text Link to Item
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Lu, Christine Y., Marc S. Williams, Geoffrey S. Ginsburg, Sengwee Toh, Jeff S. Brown, and Muin J. Khoury. “A proposed approach to accelerate evidence generation for genomic-based technologies in the context of a learning health system.” Genetics in Medicine : Official Journal of the American College of Medical Genetics 20, no. 4 (April 2018): 390–96. https://doi.org/10.1038/gim.2017.122.Full Text
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Sweeney, Timothy E., Thanneer M. Perumal, Ricardo Henao, Marshall Nichols, Judith A. Howrylak, Augustine M. Choi, Jesús F. Bermejo-Martin, et al. “A community approach to mortality prediction in sepsis via gene expression analysis.” Nat Commun 9, no. 1 (February 15, 2018): 694. https://doi.org/10.1038/s41467-018-03078-2.Full Text Link to Item
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Crucian, Brian E., Alexander Choukèr, Richard J. Simpson, Satish Mehta, Gailen Marshall, Scott M. Smith, Sara R. Zwart, et al. “Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions.” Front Immunol 9 (2018): 1437. https://doi.org/10.3389/fimmu.2018.01437.Full Text Link to Item
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Poore, Gregory D., Emily R. Ko, Ashlee Valente, Ricardo Henao, Kelsey Sumner, Christopher Hong, Thomas W. Burke, et al. “A miRNA Host Response Signature Accurately Discriminates Acute Respiratory Infection Etiologies.” Front Microbiol 9 (2018): 2957. https://doi.org/10.3389/fmicb.2018.02957.Full Text Open Access Copy Link to Item
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Phillips, Kathryn A., Patricia A. Deverka, Harold C. Sox, Muin J. Khoury, Lewis G. Sandy, Geoffrey S. Ginsburg, Sean R. Tunis, Lori A. Orlando, and Michael P. Douglas. “Making genomic medicine evidence-based and patient-centered: a structured review and landscape analysis of comparative effectiveness research.” Genet Med 19, no. 10 (October 2017): 1081–91. https://doi.org/10.1038/gim.2017.21.Full Text Open Access Copy Link to Item
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Ginsburg, Geoffrey S. “RESPONSE: Training in Precision Cardiology The Time Is Now.” Journal of the American College of Cardiology 70, no. 13 (September 26, 2017): 1678–79.Link to Item
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Cirulli, E. T., and G. S. Ginsburg. “Studying genetic resilience to improve human health.” Oral Dis 23, no. 6 (September 2017): 685–88. https://doi.org/10.1111/odi.12567.Full Text Link to Item
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Sperber, Nina R., Janet S. Carpenter, Larisa H. Cavallari, Laura J Damschroder, Rhonda M. Cooper-DeHoff, Joshua C. Denny, Geoffrey S. Ginsburg, et al. “Challenges and strategies for implementing genomic services in diverse settings: experiences from the Implementing GeNomics In pracTicE (IGNITE) network.” Bmc Med Genomics 10, no. 1 (May 22, 2017): 35. https://doi.org/10.1186/s12920-017-0273-2.Full Text Open Access Copy Link to Item
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Yang, N. Y., R. Q. Wolever, R. Roberts, A. Perlman, R. J. Dolor, D. I. Abrams, G. S. Ginsburg, and L. A. Simmons. “Integrative health care services utilization as a function of body mass index: A BraveNet practice-based research network study.” Advances in Integrative Medicine 4, no. 1 (April 1, 2017): 14–21. https://doi.org/10.1016/j.aimed.2017.02.003.Full Text
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Burke, Thomas W., Ricardo Henao, Erik Soderblom, Ephraim L. Tsalik, J Will Thompson, Micah T. McClain, Marshall Nichols, et al. “Nasopharyngeal Protein Biomarkers of Acute Respiratory Virus Infection.” Ebiomedicine 17 (March 2017): 172–81. https://doi.org/10.1016/j.ebiom.2017.02.015.Full Text Open Access Copy Link to Item
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Haga, Susanne B., Rachel Mills, Jivan Moaddeb, Nancy Allen LaPointe, Alex Cho, and Geoffrey S. Ginsburg. “Primary care providers' use of pharmacist support for delivery of pharmacogenetic testing.” Pharmacogenomics 18, no. 4 (March 2017): 359–67. https://doi.org/10.2217/pgs-2016-0177.Full Text Link to Item
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Wang, Liuyang, Emily R. Ko, James J. Gilchrist, Kelly J. Pittman, Anna Rautanen, Matti Pirinen, J Will Thompson, et al. “Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis.” Sci Adv 3, no. 3 (March 2017): e1602096. https://doi.org/10.1126/sciadv.1602096.Full Text Open Access Copy Link to Item
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Sobel Leonard, Ashley, Micah T. McClain, Gavin J. D. Smith, David E. Wentworth, Rebecca A. Halpin, Xudong Lin, Amy Ransier, et al. “The effective rate of influenza reassortment is limited during human infection.” Plos Pathog 13, no. 2 (February 2017): e1006203. https://doi.org/10.1371/journal.ppat.1006203.Full Text Link to Item
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Voora, Deepak, Adrian Coles, Kerry L. Lee, Udo Hoffmann, James A. Wingrove, Brian Rhees, Lin Huang, et al. “An age- and sex-specific gene expression score is associated with revascularization and coronary artery disease: Insights from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial.” Am Heart J 184 (February 2017): 133–40. https://doi.org/10.1016/j.ahj.2016.11.004.Full Text Link to Item
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Wu, R Ryanne, Rachel A. Myers, Elizabeth R. Hauser, Allison Vorderstrasse, Alex Cho, Geoffrey S. Ginsburg, and Lori A. Orlando. “Impact of Genetic Testing and Family Health History Based Risk Counseling on Behavior Change and Cognitive Precursors for Type 2 Diabetes.” J Genet Couns 26, no. 1 (February 2017): 133–40. https://doi.org/10.1007/s10897-016-9988-z.Full Text Open Access Copy Link to Item
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Apple, Fred S., Louise Cullen, G Michael Felker, Geoffrey Ginsburg, and David Morrow. “Cardiovascular Disease: Impact of Biomarkers, Proteomics, and Genomics.” Clin Chem 63, no. 1 (January 2017): 1–4. https://doi.org/10.1373/clinchem.2016.263350.Full Text Link to Item
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Ginsburg, Geoffrey S. “Genomics-Inspired Biomarkers and Diagnostics-Where Are They?” Clin Chem 63, no. 1 (January 2017): 255–57. https://doi.org/10.1373/clinchem.2016.266114.Full Text Link to Item
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Yan, Qin, Sun Hee Ahn, Felix Mba Medie, Batu K. Sharma-Kuinkel, Lawrence P. Park, William K. Scott, Hitesh Deshmukh, et al. “Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans.” Plos One 12, no. 6 (2017): e0179033. https://doi.org/10.1371/journal.pone.0179033.Full Text Link to Item
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Sobel Leonard, Ashley, Micah T. McClain, Gavin J. D. Smith, David E. Wentworth, Rebecca A. Halpin, Xudong Lin, Amy Ransier, et al. “Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification.” J Virol 90, no. 24 (December 15, 2016): 11247–58. https://doi.org/10.1128/JVI.01657-16.Full Text Link to Item
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Ohman, E Magnus, Pamela S. Douglas, L Blue Dean, and Geoffrey S. Ginsburg. “Philanthropy for Science: Is It a Viable Option?” Circ Res 119, no. 10 (October 28, 2016): 1057–59. https://doi.org/10.1161/CIRCRESAHA.116.309657.Full Text Link to Item
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Dzau, Victor J., and Geoffrey S. Ginsburg. “Realizing the Full Potential of Precision Medicine in Health and Health Care.” Jama 316, no. 16 (October 25, 2016): 1659–60. https://doi.org/10.1001/jama.2016.14117.Full Text Link to Item
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Haga, Susanne B., Rachel Mills, Jivan Moaddeb, Nancy Allen Lapointe, Alex Cho, and Geoffrey S. Ginsburg. “Patient experiences with pharmacogenetic testing in a primary care setting.” Pharmacogenomics 17, no. 15 (October 2016): 1629–36. https://doi.org/10.2217/pgs-2016-0077.Full Text Link to Item
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Orlando, Lori A., R Ryanne Wu, Rachel A. Myers, Adam H. Buchanan, Vincent C. Henrich, Elizabeth R. Hauser, and Geoffrey S. Ginsburg. “Clinical utility of a Web-enabled risk-assessment and clinical decision support program.” Genet Med 18, no. 10 (October 2016): 1020–28. https://doi.org/10.1038/gim.2015.210.Full Text Open Access Copy Link to Item
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Voora, Deepak, A Koneti Rao, Gauthami S. Jalagadugula, Rachel Myers, Emily Harris, Thomas L. Ortel, and Geoffrey S. Ginsburg. “Systems Pharmacogenomics Finds RUNX1 Is an Aspirin-Responsive Transcription Factor Linked to Cardiovascular Disease and Colon Cancer.” Ebiomedicine 11 (September 2016): 157–64. https://doi.org/10.1016/j.ebiom.2016.08.021.Full Text Link to Item
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Manolio, T. A., R. Ward, and G. S. Ginsburg. “Clinical implementation of genomic medicine: the importance of global collaboration.” Expert Review of Precision Medicine and Drug Development 1, no. 4 (July 3, 2016): 349–51. https://doi.org/10.1080/23808993.2016.1192460.Full Text
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Williams, Janet K., Ann K. Cashion, Sam Shekar, and Geoffrey S. Ginsburg. “Genomics, clinical research, and learning health care systems: Strategies to improve patient care.” Nurs Outlook 64, no. 3 (May 2016): 225–28. https://doi.org/10.1016/j.outlook.2015.12.006.Full Text Link to Item
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Yang, William E., Sunil Suchindran, Bradly P. Nicholson, Micah T. McClain, Thomas Burke, Geoffrey S. Ginsburg, Clayton D. Harro, et al. “Transcriptomic Analysis of the Host Response and Innate Resilience to Enterotoxigenic Escherichia coli Infection in Humans.” J Infect Dis 213, no. 9 (May 1, 2016): 1495–1504. https://doi.org/10.1093/infdis/jiv593.Full Text Open Access Copy Link to Item
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Mullington, Janet M., Sabra M. Abbott, Judith E. Carroll, Christopher J. Davis, Derk-Jan Dijk, David F. Dinges, Philip R. Gehrman, et al. “Developing Biomarker Arrays Predicting Sleep and Circadian-Coupled Risks to Health.” Sleep 39, no. 4 (April 1, 2016): 727–36. https://doi.org/10.5665/sleep.5616.Full Text Link to Item
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McClain, M. T., R. Henao, J. Williams, B. Nicholson, T. Veldman, L. Hudson, E. L. Tsalik, et al. “Differential evolution of peripheral cytokine levels in symptomatic and asymptomatic responses to experimental influenza virus challenge.” Clin Exp Immunol 183, no. 3 (March 2016): 441–51. https://doi.org/10.1111/cei.12736.Full Text Link to Item
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Tsalik, Ephraim L., Yanhong Li, Lori L. Hudson, Vivian H. Chu, Tiffany Himmel, Alex T. Limkakeng, Jason N. Katz, et al. “Potential Cost-effectiveness of Early Identification of Hospital-acquired Infection in Critically Ill Patients.” Ann Am Thorac Soc 13, no. 3 (March 2016): 401–13. https://doi.org/10.1513/AnnalsATS.201504-205OC.Full Text Open Access Copy Link to Item
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Liu, Tzu-Yu, Thomas Burke, Lawrence P. Park, Christopher W. Woods, Aimee K. Zaas, Geoffrey S. Ginsburg, and Alfred O. Hero. “An individualized predictor of health and disease using paired reference and target samples.” Bmc Bioinformatics 17 (January 22, 2016): 47. https://doi.org/10.1186/s12859-016-0889-9.Full Text Link to Item
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Tsalik, Ephraim L., Ricardo Henao, Marshall Nichols, Thomas Burke, Emily R. Ko, Micah T. McClain, Lori L. Hudson, et al. “Host gene expression classifiers diagnose acute respiratory illness etiology.” Sci Transl Med 8, no. 322 (January 20, 2016): 322ra11. https://doi.org/10.1126/scitranslmed.aad6873.Full Text Open Access Copy Link to Item
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Shah, Svati H., Donna Arnett, Steven R. Houser, Geoffrey S. Ginsburg, Calum MacRae, Seema Mital, Joseph Loscalzo, and Jennifer L. Hall. “Opportunities for the Cardiovascular Community in the Precision Medicine Initiative.” Circulation 133, no. 2 (January 12, 2016): 226–31. https://doi.org/10.1161/CIRCULATIONAHA.115.019475.Full Text Link to Item
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Weitzel, Kristin Wiisanen, Madeline Alexander, Barbara A. Bernhardt, Neil Calman, David J. Carey, Larisa H. Cavallari, Julie R. Field, et al. “The IGNITE network: a model for genomic medicine implementation and research.” Bmc Med Genomics 9 (January 5, 2016): 1. https://doi.org/10.1186/s12920-015-0162-5.Full Text Open Access Copy Link to Item
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McClain, Micah T., Bradly P. Nicholson, Lawrence P. Park, Tzu-Yu Liu, Alfred O. Hero, Ephraim L. Tsalik, Aimee K. Zaas, et al. “A Genomic Signature of Influenza Infection Shows Potential for Presymptomatic Detection, Guiding Early Therapy, and Monitoring Clinical Responses.” Open Forum Infect Dis 3, no. 1 (January 2016): ofw007. https://doi.org/10.1093/ofid/ofw007.Full Text Open Access Copy Link to Item
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Wu, R Ryanne, Rachel A. Myers, Catherine A. McCarty, David Dimmock, Michael Farrell, Deanna Cross, Troy D. Chinevere, Geoffrey S. Ginsburg, Lori A. Orlando, and Lori A. Family Health History Network. “Protocol for the "Implementation, adoption, and utility of family history in diverse care settings" study.” Implement Sci 10 (November 24, 2015): 163. https://doi.org/10.1186/s13012-015-0352-8.Full Text Open Access Copy Link to Item
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Kraus, William E., Christopher B. Granger, Michael H. Sketch, Mark P. Donahue, Geoffrey S. Ginsburg, Elizabeth R. Hauser, Carol Haynes, et al. “A Guide for a Cardiovascular Genomics Biorepository: the CATHGEN Experience.” J Cardiovasc Transl Res 8, no. 8 (November 2015): 449–57. https://doi.org/10.1007/s12265-015-9648-y.Full Text Link to Item
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Mullington, Janet, Allan I. Pack, and Geoffrey S. Ginsburg. “In Pursuit of Sleep-Circadian Biomarkers.” Sleep 38, no. 11 (November 1, 2015): 1665–66. https://doi.org/10.5665/sleep.5132.Full Text Link to Item
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Voils, Corrine I., Cynthia J. Coffman, Janet M. Grubber, David Edelman, Azita Sadeghpour, Matthew L. Maciejewski, Jamiyla Bolton, Alex Cho, Geoffrey S. Ginsburg, and William S. Yancy. “Does Type 2 Diabetes Genetic Testing and Counseling Reduce Modifiable Risk Factors? A Randomized Controlled Trial of Veterans.” J Gen Intern Med 30, no. 11 (November 2015): 1591–98. https://doi.org/10.1007/s11606-015-3315-5.Full Text Link to Item
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Stafford-Smith, Mark, Yi-Ju Li, Joseph P. Mathew, Yen-Wei Li, Yunqi Ji, Barbara G. Phillips-Bute, Carmelo A. Milano, et al. “Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci.” Kidney Int 88, no. 4 (October 2015): 823–32. https://doi.org/10.1038/ki.2015.161.Full Text Open Access Copy Link to Item
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Tsalik, Ephraim L., Laurel K. Willig, Brandon J. Rice, Jennifer C. van Velkinburgh, Robert P. Mohney, Jonathan E. McDunn, Darrell L. Dinwiddie, et al. “Renal systems biology of patients with systemic inflammatory response syndrome.” Kidney Int 88, no. 4 (October 2015): 804–14. https://doi.org/10.1038/ki.2015.150.Full Text Open Access Copy Link to Item
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Friede, Kevin A., Geoffrey S. Ginsburg, and Deepak Voora. “Gene Expression Signatures and the Spectrum of Coronary Artery Disease.” J Cardiovasc Transl Res 8, no. 6 (August 2015): 339–52. https://doi.org/10.1007/s12265-015-9640-6.Full Text Link to Item
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David, Sean P., Samuel G. Johnson, Adam C. Berger, W Gregory Feero, Sharon F. Terry, Larry A. Green, Robert L. Phillips, and Geoffrey S. Ginsburg. “Making Personalized Health Care Even More Personalized: Insights From Activities of the IOM Genomics Roundtable.” Ann Fam Med 13, no. 4 (July 2015): 373–80. https://doi.org/10.1370/afm.1772.Full Text Link to Item
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Manolio, Teri A., Marc Abramowicz, Fahd Al-Mulla, Warwick Anderson, Rudi Balling, Adam C. Berger, Steven Bleyl, et al. “Global implementation of genomic medicine: We are not alone.” Sci Transl Med 7, no. 290 (June 3, 2015): 290ps13. https://doi.org/10.1126/scitranslmed.aab0194.Full Text Link to Item
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Dzau, Victor J., Geoffrey S. Ginsburg, Karen Van Nuys, David Agus, and Dana Goldman. “Aligning incentives to fulfil the promise of personalised medicine.” Lancet 385, no. 9982 (May 23, 2015): 2118–19. https://doi.org/10.1016/S0140-6736(15)60722-X.Full Text Link to Item
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Katsanis, Sara Huston, Mollie A. Minear, Allison Vorderstrasse, Nancy Yang, Jason W. Reeves, Tejinder Rakhra-Burris, Robert Cook-Deegan, Geoffrey S. Ginsburg, and Leigh Ann Simmons. “Perspectives on genetic and genomic technologies in an academic medical center: the duke experience.” J Pers Med 5, no. 2 (April 3, 2015): 67–82. https://doi.org/10.3390/jpm5020067.Full Text Open Access Copy Link to Item
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Buchanan, Adam H., Carol A. Christianson, Tiffany Himmel, Karen P. Powell, Astrid Agbaje, Geoffrey S. Ginsburg, Vincent C. Henrich, and Lori A. Orlando. “Use of a patient-entered family health history tool with decision support in primary care: impact of identification of increased risk patients on genetic counseling attendance.” J Genet Couns 24, no. 1 (February 2015): 179–88. https://doi.org/10.1007/s10897-014-9753-0.Full Text Link to Item
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Gallagher, Patrick, Heather A. King, Susanne B. Haga, Lori A. Orlando, Scott V. Joy, Gloria M. Trujillo, William Michael Scott, et al. “Patient beliefs and behaviors about genomic risk for type 2 diabetes: implications for prevention.” J Health Commun 20, no. 6 (2015): 728–35. https://doi.org/10.1080/10810730.2015.1018563.Full Text Open Access Copy Link to Item
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Ko, Emily R., William E. Yang, Micah T. McClain, Christopher W. Woods, Geoffrey S. Ginsburg, and Ephraim L. Tsalik. “What was old is new again: using the host response to diagnose infectious disease.” Expert Rev Mol Diagn 15, no. 9 (2015): 1143–58. https://doi.org/10.1586/14737159.2015.1059278.Full Text Link to Item
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Li, Josephine H., Sunil Suchindran, Svati H. Shah, William E. Kraus, Geoffrey S. Ginsburg, and Deepak Voora. “SLCO1B1 genetic variants, long-term low-density lipoprotein cholesterol levels and clinical events in patients following cardiac catheterization.” Pharmacogenomics 16, no. 5 (2015): 449–58. https://doi.org/10.2217/pgs.15.2.Full Text Link to Item
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Rose, Jason J., Deepak Voora, Derek D. Cyr, Joseph E. Lucas, Aimee K. Zaas, Christopher W. Woods, L Kristin Newby, William E. Kraus, and Geoffrey S. Ginsburg. “Gene Expression Profiles Link Respiratory Viral Infection, Platelet Response to Aspirin, and Acute Myocardial Infarction.” Plos One 10, no. 7 (2015): e0132259. https://doi.org/10.1371/journal.pone.0132259.Full Text Open Access Copy Link to Item
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Vorderstrasse, Allison, Sara Huston Katsanis, Mollie A. Minear, Nancy Yang, Tejinder Rakhra-Burris, Jason W. Reeves, Robert Cook-Deegan, Geoffrey S. Ginsburg, and Leigh Ann Simmons. “Perceptions of Personalized Medicine in an Academic Health System: Educational Findings.” J Contemp Med Educ 3, no. 1 (2015): 14–19. https://doi.org/10.5455/jcme.20150408050414.Full Text Open Access Copy Link to Item
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Suchindran, Sunil, Tiffany Himmel, Thomas L. Ortel, Richard C. Becker, William E. Kraus, L. K. Newby, Geoffrey S. Ginsburg, and Deepak Voora. “Aspirin-Responsive Platelet Genes Are Associated With Platelet Function and Cardiovascular Events.” Circulation 130 (November 25, 2014).Link to Item
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Zaas, Aimee K., Bronwen H. Garner, Ephraim L. Tsalik, Thomas Burke, Christopher W. Woods, and Geoffrey S. Ginsburg. “The current epidemiology and clinical decisions surrounding acute respiratory infections.” Trends Mol Med 20, no. 10 (October 2014): 579–88. https://doi.org/10.1016/j.molmed.2014.08.001.Full Text Link to Item
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Haga, Susanne B., Nancy M Allen LaPointe, Alex Cho, Shelby D. Reed, Rachel Mills, Jivan Moaddeb, and Geoffrey S. Ginsburg. “Pilot study of pharmacist-assisted delivery of pharmacogenetic testing in a primary care setting.” Pharmacogenomics 15, no. 13 (September 2014): 1677–86. https://doi.org/10.2217/pgs.14.109.Full Text Link to Item
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Benjamin, Ashlee M., Marshall Nichols, Thomas W. Burke, Geoffrey S. Ginsburg, and Joseph E. Lucas. “Comparing reference-based RNA-Seq mapping methods for non-human primate data.” Bmc Genomics 15 (July 7, 2014): 570. https://doi.org/10.1186/1471-2164-15-570.Full Text Link to Item
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Stevenson, Marvaretta, Jared Christensen, Debra Shoemaker, Traci Foster, William T. Barry, Betty C. Tong, Momen Wahidi, et al. “Tumor acquisition for biomarker research in lung cancer.” Cancer Invest 32, no. 6 (July 2014): 291–98. https://doi.org/10.3109/07357907.2014.911880.Full Text Link to Item
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Beadles, Chris A., R. Ryanne Wu, Tiffany Himmel, Adam H. Buchanan, Karen P. Powell, Elizabeth Hauser, Vincent C. Henrich, Geoffrey S. Ginsburg, and Lori A. Orlando. “Providing patient education: impact on quantity and quality of family health history collection.” Fam Cancer 13, no. 2 (June 2014): 325–32. https://doi.org/10.1007/s10689-014-9701-z.Full Text Link to Item
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Kraft, Bryan D., Claude A. Piantadosi, Ashlee M. Benjamin, Joseph E. Lucas, Aimee K. Zaas, Marisol Betancourt-Quiroz, Christopher W. Woods, et al. “Development of a novel preclinical model of pneumococcal pneumonia in nonhuman primates.” Am J Respir Cell Mol Biol 50, no. 5 (May 2014): 995–1004. https://doi.org/10.1165/rcmb.2013-0340OC.Full Text Link to Item
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Ngo, Hoan T., Hsin-Neng Wang, Thomas Burke, Geoffrey S. Ginsburg, and Tuan Vo-Dinh. “Multiplex detection of disease biomarkers using SERS molecular sentinel-on-chip.” Anal Bioanal Chem 406, no. 14 (May 2014): 3335–44. https://doi.org/10.1007/s00216-014-7648-4.Full Text Link to Item
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Power, Aidan, Adam C. Berger, and Geoffrey S. Ginsburg. “Genomics-enabled drug repositioning and repurposing: insights from an IOM Roundtable activity.” Jama 311, no. 20 (May 2014): 2063–64. https://doi.org/10.1001/jama.2014.3002.Full Text Link to Item
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Ginsburg, Geoffrey. “Medical genomics: Gather and use genetic data in health care.” Nature 508, no. 7497 (April 24, 2014): 451–53. https://doi.org/10.1038/508451a.Full Text Link to Item
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Kertai, Miklos D., Stephen A. Esper, Igor Akushevich, Deepak Voora, Geoffrey S. Ginsburg, Mark Stafford-Smith, Katherine Grichnik, et al. “Preoperative CYP2D6 metabolism-dependent β-blocker use and mortality after coronary artery bypass grafting surgery.” J Thorac Cardiovasc Surg 147, no. 4 (April 2014): 1368-1375.e3. https://doi.org/10.1016/j.jtcvs.2013.09.067.Full Text Open Access Copy Link to Item
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Li, Josephine H., Scott V. Joy, Susanne B. Haga, Lori A. Orlando, William E. Kraus, Geoffrey S. Ginsburg, and Deepak Voora. “Genetically guided statin therapy on statin perceptions, adherence, and cholesterol lowering: a pilot implementation study in primary care patients.” J Pers Med 4, no. 2 (March 27, 2014): 147–62. https://doi.org/10.3390/jpm4020147.Full Text Link to Item
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Hudson, Lori L., Christopher W. Woods, and Geoffrey S. Ginsburg. “A novel diagnostic approach may reduce inappropriate antibiotic use for acute respiratory infections.” Expert Rev Anti Infect Ther 12, no. 3 (March 2014): 279–82. https://doi.org/10.1586/14787210.2014.881717.Full Text Link to Item
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Orlando, Lori A., R Ryanne Wu, Chris Beadles, Tiffany Himmel, Adam H. Buchanan, Karen P. Powell, Elizabeth R. Hauser, Vincent C. Henrich, and Geoffrey S. Ginsburg. “Implementing family health history risk stratification in primary care: impact of guideline criteria on populations and resource demand.” Am J Med Genet C Semin Med Genet 166C, no. 1 (March 2014): 24–33. https://doi.org/10.1002/ajmg.c.31388.Full Text Link to Item
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Wu, R Ryanne, Tiffany L. Himmel, Adam H. Buchanan, Karen P. Powell, Elizabeth R. Hauser, Geoffrey S. Ginsburg, Vincent C. Henrich, and Lori A. Orlando. “Quality of family history collection with use of a patient facing family history assessment tool.” Bmc Fam Pract 15 (February 13, 2014): 31. https://doi.org/10.1186/1471-2296-15-31.Full Text Link to Item
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Haga, S. B., W. T. Barry, R. Mills, L. Svetkey, S. Suchindran, H. F. Willard, and G. S. Ginsburg. “Impact of delivery models on understanding genomic risk for type 2 diabetes.” Public Health Genomics 17, no. 2 (2014): 95–104. https://doi.org/10.1159/000358413.Full Text Link to Item
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Tsalik, Ephraim L., Raymond J. Langley, Darrell L. Dinwiddie, Neil A. Miller, Byunggil Yoo, Jennifer C. van Velkinburgh, Laurie D. Smith, et al. “An integrated transcriptome and expressed variant analysis of sepsis survival and death.” Genome Med 6, no. 11 (2014): 111. https://doi.org/10.1186/s13073-014-0111-5.Full Text Open Access Copy Link to Item
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Voora, Deepak, Geoffrey S. Ginsburg, and Axel Akerblom. “Platelet RNA as a novel biomarker for the response to antiplatelet therapy.” Future Cardiol 10, no. 1 (January 2014): 9–12. https://doi.org/10.2217/fca.13.90.Full Text Link to Item
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Wu, R. R., T. L. Himmel, A. H. Buchanan, K. P. Powell, E. R. Hauser, G. S. Ginsburg, V. C. Henrich, and L. A. Orlando. “Quality of family history collection with use of a patient facing family history assessment tool.” Bmc Family Practice 15, no. 1 (2014). https://doi.org/10.1186/1471-2296-15-31.Full Text
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Xing, Z., B. Nicholson, M. Jimenez, T. Veldman, L. Hudson, J. Lucas, D. Dunson, et al. “Bayesian modeling of temporal properties of infectious disease in a college student population.” Journal of Applied Statistics 41, no. 6 (January 1, 2014): 1358–82. https://doi.org/10.1080/02664763.2013.870138.Full Text
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McClain, Micah T., Lawrence P. Park, Bradly Nicholson, Timothy Veldman, Aimee K. Zaas, Ron Turner, Robert Lambkin-Williams, Anthony S. Gilbert, Geoffrey S. Ginsburg, and Christopher W. Woods. “Longitudinal analysis of leukocyte differentials in peripheral blood of patients with acute respiratory viral infections.” J Clin Virol 58, no. 4 (December 2013): 689–95. https://doi.org/10.1016/j.jcv.2013.09.015.Full Text Link to Item
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Katsanis, Sara H., Jennifer R. Dungan, Catherine L. Gilliss, and Geoffrey A. Ginsburg. “Educating future providers of personalized medicine.” N C Med J 74, no. 6 (November 2013): 491–92.Open Access Copy Link to Item
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Cohen, Matan J., Geoffrey S. Ginsburg, Edward Abrahams, Haim Bitterman, and Eddy Karnieli. “Overcoming barriers in the implementation of personalized medicine into clinical practice.” Isr Med Assoc J 15, no. 10 (October 2013): 599–601.Link to Item
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Voora, Deepak, Derek Cyr, Joseph Lucas, Jen-Tsan Chi, Jennifer Dungan, Timothy A. McCaffrey, Richard Katz, et al. “Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events.” J Am Coll Cardiol 62, no. 14 (October 1, 2013): 1267–76. https://doi.org/10.1016/j.jacc.2013.05.073.Full Text Link to Item
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Zaas, Aimee K., Thomas Burke, Minhua Chen, Micah McClain, Bradly Nicholson, Timothy Veldman, Ephraim L. Tsalik, et al. “A host-based RT-PCR gene expression signature to identify acute respiratory viral infection.” Sci Transl Med 5, no. 203 (September 18, 2013): 203ra126. https://doi.org/10.1126/scitranslmed.3006280.Full Text Link to Item
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Manolio, Teri A., Rex L. Chisholm, Brad Ozenberger, Dan M. Roden, Marc S. Williams, Richard Wilson, David Bick, et al. “Implementing Genomic Medicine in the Clinic: The Future Is Here EDITORIAL COMMENT.” Obstetrical & Gynecological Survey 68, no. 9 (September 1, 2013): 621–23.Link to Item
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Ginsburg, G. S. “Application of Human Genome Information to Clinical Practice” 1 (August 29, 2013): 204–15. https://doi.org/10.1016/B978-0-12-382227-7.00017-3.Full Text
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Ginsburg, G., and H. Willard. “Genomic and Personalized Medicine.” Genomic and Personalized Medicine 1–2 (August 26, 2013).
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Wu, R Ryanne, Lori A. Orlando, Tiffany L. Himmel, Adam H. Buchanan, Karen P. Powell, Elizabeth R. Hauser, Astrid B. Agbaje, Vincent C. Henrich, and Geoffrey S. Ginsburg. “Patient and primary care provider experience using a family health history collection, risk stratification, and clinical decision support tool: a type 2 hybrid controlled implementation-effectiveness trial.” Bmc Fam Pract 14 (August 6, 2013): 111. https://doi.org/10.1186/1471-2296-14-111.Full Text Link to Item
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Vorderstrasse, Allison A., Alex Cho, Corrine I. Voils, Lori A. Orlando, and Geoffrey S. Ginsburg. “Clinical utility of genetic risk testing in primary care: the example of Type 2 diabetes.” Per Med 10, no. 6 (August 2013): 549–63. https://doi.org/10.2217/pme.13.47.Full Text Link to Item
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Langley, Raymond J., Ephraim L. Tsalik, Jennifer C. van Velkinburgh, Seth W. Glickman, Brandon J. Rice, Chunping Wang, Bo Chen, et al. “An integrated clinico-metabolomic model improves prediction of death in sepsis.” Sci Transl Med 5, no. 195 (July 24, 2013): 195ra95. https://doi.org/10.1126/scitranslmed.3005893.Full Text Link to Item
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Wang, Hsin-Neng, Andrew M. Fales, Aimee K. Zaas, Christopher W. Woods, Thomas Burke, Geoffrey S. Ginsburg, and Tuan Vo-Dinh. “Surface-enhanced Raman scattering molecular sentinel nanoprobes for viral infection diagnostics.” Anal Chim Acta 786 (July 5, 2013): 153–58. https://doi.org/10.1016/j.aca.2013.05.017.Full Text Link to Item
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Simonds, Naoko I., Muin J. Khoury, Sheri D. Schully, Katrina Armstrong, Wendy F. Cohn, David A. Fenstermacher, Geoffrey S. Ginsburg, et al. “Comparative effectiveness research in cancer genomics and precision medicine: current landscape and future prospects.” J Natl Cancer Inst 105, no. 13 (July 3, 2013): 929–36. https://doi.org/10.1093/jnci/djt108.Full Text Link to Item
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Orlando, Lori A., Adam H. Buchanan, Susan E. Hahn, Carol A. Christianson, Karen P. Powell, Celette Sugg Skinner, Blair Chesnut, et al. “Development and validation of a primary care-based family health history and decision support program (MeTree).” N C Med J 74, no. 4 (July 2013): 287–96.Link to Item
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Powell, Karen P., Carol A. Christianson, Susan E. Hahn, Gaurav Dave, Leslie R. Evans, Susan H. Blanton, Elizabeth Hauser, et al. “Collection of family health history for assessment of chronic disease risk in primary care.” N C Med J 74, no. 4 (July 2013): 279–86.Link to Item
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McCarthy, Jeanette J., Howard L. McLeod, and Geoffrey S. Ginsburg. “Genomic medicine: a decade of successes, challenges, and opportunities.” Sci Transl Med 5, no. 189 (June 12, 2013): 189sr4. https://doi.org/10.1126/scitranslmed.3005785.Full Text Link to Item
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Henao, R., J. W. Thompson, M. A. Moseley, G. S. Ginsburg, L. Carin, and J. E. Lucas. “Latent protein trees.” Annals of Applied Statistics 7, no. 2 (June 1, 2013): 691–713. https://doi.org/10.1214/13-AOAS639.Full Text Open Access Copy
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Tenenbaum, Jay M Marty, Amy P. Abernethy, Abhijit Ron Mazumder, and Geoffrey S. Ginsburg. “The Impact of Personalized Medicine.” Scientist 27, no. 6 (June 1, 2013): 64–65.Link to Item
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Orlando, Lori A., Vincent C. Henrich, Elizabeth R. Hauser, Charles Wilson, Geoffrey S. Ginsburg, and Geoffrey S. Genomedical Connection. “The genomic medicine model: an integrated approach to implementation of family health history in primary care.” Per Med 10, no. 3 (May 2013): 295–306. https://doi.org/10.2217/pme.13.20.Full Text Link to Item
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Vorderstrasse, Allison A., Geoffrey S. Ginsburg, William E. Kraus, Maj Carlos J. Maldonado, and Ruth Q. Wolever. “Health coaching and genomics-potential avenues to elicit behavior change in those at risk for chronic disease: protocol for personalized medicine effectiveness study in air force primary care.” Glob Adv Health Med 2, no. 3 (May 2013): 26–38. https://doi.org/10.7453/gahmj.2013.035.Full Text Link to Item
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Ginsburg, Geoffrey S. “Realizing the opportunities of genomics in health care.” Jama 309, no. 14 (April 10, 2013): 1463–64. https://doi.org/10.1001/jama.2013.1465.Full Text Link to Item
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Haga, Susanne B., William T. Barry, Rachel Mills, Geoffrey S. Ginsburg, Laura Svetkey, Jennifer Sullivan, and Huntington F. Willard. “Public knowledge of and attitudes toward genetics and genetic testing.” Genet Test Mol Biomarkers 17, no. 4 (April 2013): 327–35. https://doi.org/10.1089/gtmb.2012.0350.Full Text Link to Item
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Khoury, Muin J., Tram Kim Lam, John P. A. Ioannidis, Patricia Hartge, Margaret R. Spitz, Julie E. Buring, Stephen J. Chanock, et al. “Transforming epidemiology for 21st century medicine and public health.” Cancer Epidemiol Biomarkers Prev 22, no. 4 (April 2013): 508–16. https://doi.org/10.1158/1055-9965.EPI-13-0146.Full Text Link to Item
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Manolio, Teri A., Rex L. Chisholm, Brad Ozenberger, Dan M. Roden, Marc S. Williams, Richard Wilson, David Bick, et al. “Implementing genomic medicine in the clinic: the future is here.” Genet Med 15, no. 4 (April 2013): 258–67. https://doi.org/10.1038/gim.2012.157.Full Text Link to Item
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Bazot, Cécile, Nicolas Dobigeon, Jean-Yves Tourneret, Aimee K. Zaas, Geoffrey S. Ginsburg, and Alfred O. Hero. “Unsupervised Bayesian linear unmixing of gene expression microarrays.” Bmc Bioinformatics 14 (March 19, 2013): 99. https://doi.org/10.1186/1471-2105-14-99.Full Text Link to Item
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Haga, S. B., W. Burke, G. S. Ginsburg, R. Mills, and R. Agans. “Primary care physicians' knowledge of and experience with pharmacogenetic testing.” Obstetrical and Gynecological Survey 68, no. 2 (February 1, 2013): 91–93. https://doi.org/10.1097/01.ogx.0000427617.89027.ca.Full Text
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Yang, N., G. S. Ginsburg, and L. A. Simmons. “Personalized medicine in women's obesity prevention and treatment: implications for research, policy and practice.” Obes Rev 14, no. 2 (February 2013): 145–61. https://doi.org/10.1111/j.1467-789X.2012.01048.x.Full Text Link to Item
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Ahn, Sun Hee, Ephraim L. Tsalik, Derek D. Cyr, Yurong Zhang, Jennifer C. van Velkinburgh, Raymond J. Langley, Seth W. Glickman, et al. “Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans.” Plos One 8, no. 1 (2013): e48979. https://doi.org/10.1371/journal.pone.0048979.Full Text Open Access Copy Link to Item
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Henao, Ricardo, Jared Murray, Geoffrey Ginsburg, Lawrence Carin, and Joseph E. Lucas. “Patient clustering with uncoded text in electronic medical records.” Amia Annu Symp Proc 2013 (2013): 592–99.Link to Item
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Manolio, T. A., R. L. Chisholm, B. Ozenberger, D. M. Roden, M. S. Williams, R. Wilson, D. Bick, et al. “Implementing genomic medicine in the clinic: The future is here.” Obstetrical and Gynecological Survey 68, no. 9 (2013): 621–23. https://doi.org/10.1097/01.ogx.0000435523.89711.77.Full Text
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Rose, J. J., D. Voora, D. D. Cyr, J. E. Lucas, A. K. Zaas, L. K. Newby, W. E. Kraus, and G. S. Ginsburg. “Blood Gene Expression Profiling Reveals An Association Between Viral Infection, Platelet Function, And Acute Myocardial Infarction.” American Journal of Respiratory and Critical Care Medicine 187 (January 1, 2013).Link to Item
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Woods, Christopher W., Micah T. McClain, Minhua Chen, Aimee K. Zaas, Bradly P. Nicholson, Jay Varkey, Timothy Veldman, et al. “A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2.” Plos One 8, no. 1 (2013): e52198. https://doi.org/10.1371/journal.pone.0052198.Full Text Open Access Copy Link to Item
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Xing, Z., B. Nicholson, M. Jimenez, T. Veldman, L. Hudson, J. Lucas, D. Dunson, et al. “Bayesian modeling of temporal properties of infectious disease in a college student population.” Journal of Applied Statistics, 2013.
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Kuderer, N. M., W. T. Barry, J. Geradts, G. S. Ginsburg, G. H. Lyman, M. Datto, V. Liotcheva, et al. “Abstract P2-10-03: A cross-platform comparison of genomic signatures and OncotypeDx score to discover potential prognostic/predictive genes and pathways.” Poster Session Abstracts, December 15, 2012. https://doi.org/10.1158/0008-5472.sabcs12-p2-10-03.Full Text
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Lyman, G. H., E. Culakova, M. S. Poniewierski, A. F. Wogu, W. Barry, G. S. Ginsburg, P. K. Marcom, et al. “Abstract P3-06-07: Ki67 as a Predictive Marker of Response to Neoadjuvant Chemotherapy in Patients with Early-Stage Breast Cancer (ESBC): A Systematic Review and Evidence Summary.” Poster Session Abstracts, December 15, 2012. https://doi.org/10.1158/0008-5472.sabcs12-p3-06-07.Full Text
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Ginsburg, Geoffrey S., and Nicole M. Kuderer. “Comparative effectiveness research, genomics-enabled personalized medicine, and rapid learning health care: a common bond.” J Clin Oncol 30, no. 34 (December 1, 2012): 4233–42. https://doi.org/10.1200/JCO.2012.42.6114.Full Text Link to Item
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Ginsburg, Geoffrey S., and Christopher W. Woods. “The host response to infection: advancing a novel diagnostic paradigm.” Crit Care 16, no. 6 (November 6, 2012): 168. https://doi.org/10.1186/cc11685.Full Text Link to Item
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Haga, S. B., W. Burke, G. S. Ginsburg, R. Mills, and R. Agans. “Primary care physicians' knowledge of and experience with pharmacogenetic testing.” Clin Genet 82, no. 4 (October 2012): 388–94. https://doi.org/10.1111/j.1399-0004.2012.01908.x.Full Text Link to Item
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Mills, Rachel A., Susanne B. Haga, and Geoffrey S. Ginsburg. “Genetic testing: clinical and personal utility.” Virtual Mentor 14, no. 8 (August 1, 2012): 604–9. https://doi.org/10.1001/virtualmentor.2012.14.8.ecas1-1208.Full Text Link to Item
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Voils, Corrine I., Cynthia J. Coffman, David Edelman, Matthew L. Maciejewski, Janet M. Grubber, Azita Sadeghpour, Alex Cho, et al. “Examining the impact of genetic testing for type 2 diabetes on health behaviors: study protocol for a randomized controlled trial.” Trials 13 (August 1, 2012): 121. https://doi.org/10.1186/1745-6215-13-121.Full Text Link to Item
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Voora, Deepak, and Geoffrey S. Ginsburg. “Clinical application of cardiovascular pharmacogenetics.” J Am Coll Cardiol 60, no. 1 (July 3, 2012): 9–20. https://doi.org/10.1016/j.jacc.2012.01.067.Full Text Link to Item
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Cho, Alex H., Ley A. Killeya-Jones, Sunil Suchindran, Julianne M. O’Daniel, Kensaku Kawamoto, Susanne Haga, Joseph E. Lucas, Gloria M. Trujillo, Scott Joy, and Geoffrey S. Ginsburg. “PRELIMINARY OUTCOMES OF GENETIC RISK TESTING IN PRIMARY CARE FOR COMMON DNA VARIANTS ASSOCIATED WITH TYPE 2 DIABETES.” Journal of General Internal Medicine 27 (July 1, 2012): S278–S278.Link to Item
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Kraus, William E., Susanne B. Haga, Howard L. McLeod, Judd Staples, and Geoffrey S. Ginsburg. “Conference Scene: Is personalized medicine ready for prime time?” Per Med 9, no. 5 (July 2012): 475–78. https://doi.org/10.2217/pme.12.57.Full Text Link to Item
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Henao, R., J. W. Thompson, M. A. Moseley, G. S. Ginsburg, L. Carin, and J. E. Lucas. “Hierarchical factor modeling of proteomics data.” 2012 Ieee 2nd International Conference on Computational Advances in Bio and Medical Sciences, Iccabs 2012, May 8, 2012. https://doi.org/10.1109/ICCABS.2012.6182638.Full Text
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Eng, G., A. Chen, T. Vess, and G. S. Ginsburg. “Genome technologies and personalized dental medicine.” Oral Dis 18, no. 3 (April 2012): 223–35. https://doi.org/10.1111/j.1601-0825.2011.01876.x.Full Text Link to Item
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Voora, Deepak, Thomas L. Ortel, Joseph E. Lucas, Jen-Tsan Chi, Richard C. Becker, and Geoffrey S. Ginsburg. “Time-dependent changes in non-COX-1-dependent platelet function with daily aspirin therapy.” J Thromb Thrombolysis 33, no. 3 (April 2012): 246–57. https://doi.org/10.1007/s11239-012-0683-0.Full Text Link to Item
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Zarco, M. F., T. J. Vess, and G. S. Ginsburg. “The oral microbiome in health and disease and the potential impact on personalized dental medicine.” Oral Dis 18, no. 2 (March 2012): 109–20. https://doi.org/10.1111/j.1601-0825.2011.01851.x.Full Text Link to Item
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Cho, Alex H., Ley A. Killeya-Jones, Julianne M. O’Daniel, Kensaku Kawamoto, Patrick Gallagher, Susanne Haga, Joseph E. Lucas, Gloria M. Trujillo, Scott V. Joy, and Geoffrey S. Ginsburg. “Effect of genetic testing for risk of type 2 diabetes mellitus on health behaviors and outcomes: study rationale, development and design.” Bmc Health Serv Res 12 (January 18, 2012): 16. https://doi.org/10.1186/1472-6963-12-16.Full Text Open Access Copy Link to Item
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Bhattacharya, Sayanti, Ashley A. Dunham, Melissa A. Cornish, Victoria A. Christian, Geoffrey S. Ginsburg, Jessica D. Tenenbaum, Meredith L. Nahm, et al. “The Measurement to Understand Reclassification of Disease of Cabarrus/Kannapolis (MURDOCK) Study Community Registry and Biorepository.” Am J Transl Res 4, no. 4 (2012): 458–70.Link to Item
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Carin, Lawrence, Alfred Hero, Joseph Lucas, David Dunson, Minhua Chen, Ricardo Heñao, Arnau Tibau-Puig, Aimee Zaas, Christopher W. Woods, and Geoffrey S. Ginsburg. “High-Dimensional Longitudinal Genomic Data: An analysis used for monitoring viral infections.” Ieee Signal Process Mag 29, no. 1 (January 1, 2012): 108–23. https://doi.org/10.1109/MSP.2011.943009.Full Text Link to Item
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Ginsburg, G. S. “Application of Molecular Technologies to Clinical Medicine” 1 (January 1, 2012): 199–203. https://doi.org/10.1016/B978-1-4377-1604-7.00042-7.Full Text
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Tenenbaum, Jessica D., Victoria Christian, Melissa A. Cornish, Rowena J. Dolor, Ashley A. Dunham, Geoffrey S. Ginsburg, Virginia B. Kraus, et al. “The MURDOCK Study: a long-term initiative for disease reclassification through advanced biomarker discovery and integration with electronic health records.” Am J Transl Res 4, no. 3 (2012): 291–301.Link to Item
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Culakova, E., M. S. Poniewierski, M. Huang, N. M. Kuderer, G. S. Ginsburg, W. Barry, P. K. Marcom, N. Ready, A. Abernethy, and G. H. Lyman. “P3-14-04: Assessment of Genomic Prognostic Signatures as Predictors of Response to Neoadjuvant Chemotherapy in Patients with Early Stage Breast Cancer.” Poster Session Abstracts, December 15, 2011. https://doi.org/10.1158/0008-5472.sabcs11-p3-14-04.Full Text
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Lewis, Deborah A., Gregg J. Stashenko, Olga M. Akay, Lulit I. Price, Kouros Owzar, Geoffrey S. Ginsburg, Jen-Tsan Chi, and Thomas L. Ortel. “Whole blood gene expression analyses in patients with single versus recurrent venous thromboembolism.” Thromb Res 128, no. 6 (December 2011): 536–40. https://doi.org/10.1016/j.thromres.2011.06.003.Full Text Link to Item
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Orlando, Lori A., Elizabeth R. Hauser, Carol Christianson, Karen P. Powell, Adam H. Buchanan, Blair Chesnut, Astrid B. Agbaje, Vincent C. Henrich, and Geoffrey Ginsburg. “Protocol for implementation of family health history collection and decision support into primary care using a computerized family health history system.” Bmc Health Serv Res 11 (October 11, 2011): 264. https://doi.org/10.1186/1472-6963-11-264.Full Text Open Access Copy Link to Item
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Haga, Susanne B., Kensaku Kawamoto, Robert Agans, and Geoffrey S. Ginsburg. “Consideration of patient preferences and challenges in storage and access of pharmacogenetic test results.” Genet Med 13, no. 10 (October 2011): 887–90. https://doi.org/10.1097/GIM.0b013e31822077a5.Full Text Link to Item
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Ginsburg, Geoffrey S., Judd Staples, and Amy P. Abernethy. “Academic medical centers: ripe for rapid-learning personalized health care.” Sci Transl Med 3, no. 101 (September 21, 2011): 101cm27. https://doi.org/10.1126/scitranslmed.3002386.Full Text Link to Item
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Haga, Susanne B., Madeline M. Carrig, Julianne M. O’Daniel, Lori A. Orlando, Ley A. Killeya-Jones, Geoffrey S. Ginsburg, and Alex Cho. “Genomic risk profiling: attitudes and use in personal and clinical care of primary care physicians who offer risk profiling.” J Gen Intern Med 26, no. 8 (August 2011): 834–40. https://doi.org/10.1007/s11606-011-1651-7.Full Text Link to Item
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Huang, Yongsheng, Aimee K. Zaas, Arvind Rao, Nicolas Dobigeon, Peter J. Woolf, Timothy Veldman, N Christine Øien, et al. “Temporal dynamics of host molecular responses differentiate symptomatic and asymptomatic influenza a infection.” Plos Genet 7, no. 8 (August 2011): e1002234. https://doi.org/10.1371/journal.pgen.1002234.Full Text Open Access Copy Link to Item
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Voora, Deepak, and Geoffrey S. Ginsburg. “A hub for bench-to-bedside pharmacogenomic-based research.” Pharmacogenomics 12, no. 8 (August 2011): 1095–98. https://doi.org/10.2217/pgs.11.62.Full Text Link to Item
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Jing, Linhong, Carol E. Parker, David Seo, Maria Warren Hines, Nedyalka Dicheva, Yanbao Yu, Debra Schwinn, Geoffrey S. Ginsburg, and Xian Chen. “Discovery of biomarker candidates for coronary artery disease from an APOE-knock out mouse model using iTRAQ-based multiplex quantitative proteomics.” Proteomics 11, no. 14 (July 2011): 2763–76. https://doi.org/10.1002/pmic.201000202.Full Text Link to Item
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Patel, Keyur, Joseph E. Lucas, J Will Thompson, Laura G. Dubois, Hans L. Tillmann, Alexander J. Thompson, Diane Uzarski, et al. “High predictive accuracy of an unbiased proteomic profile for sustained virologic response in chronic hepatitis C patients.” Hepatology 53, no. 6 (June 2011): 1809–18. https://doi.org/10.1002/hep.24284.Full Text Link to Item
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Kuderer, N. M., E. Culakova, M. Huang, M. S. Poniewierski, G. S. Ginsburg, W. T. Barry, P. K. Marcom, N. Ready, A. P. Abernethy, and G. H. Lyman. “Quality appraisal of clinical validation studies for multigene prediction assays of chemotherapy response in early-stage breast cancer.” Journal of Clinical Oncology 29, no. 15_suppl (May 20, 2011): 3082–3082. https://doi.org/10.1200/jco.2011.29.15_suppl.3082.Full Text
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Kuderer, N. M., E. Culakova, M. Huang, M. S. Poniewierski, G. S. Ginsburg, W. T. Barry, P. K. Marcom, N. Ready, A. P. Abernethy, and G. H. Lyman. “Quality appraisal of clinical validation studies for multigene prediction assays of chemotherapy response in early-stage breast cancer.” J Clin Oncol 29, no. 15_suppl (May 20, 2011): 3082.Link to Item
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Elashoff, Michael R., James A. Wingrove, Philip Beineke, Susan E. Daniels, Whittemore G. Tingley, Steven Rosenberg, Szilard Voros, et al. “Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients.” Bmc Med Genomics 4 (March 28, 2011): 26. https://doi.org/10.1186/1755-8794-4-26.Full Text Open Access Copy Link to Item
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Chen, Minhua, David Carlson, Aimee Zaas, Christopher W. Woods, Geoffrey S. Ginsburg, Alfred Hero, Joseph Lucas, and Lawrence Carin. “Detection of viruses via statistical gene expression analysis.” Ieee Trans Biomed Eng 58, no. 3 (March 2011): 468–79. https://doi.org/10.1109/TBME.2010.2059702.Full Text Link to Item
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Tenenbaum, Jessica D., Patricia L. Whetzel, Kent Anderson, Charles D. Borromeo, Ivo D. Dinov, Davera Gabriel, Beth Kirschner, et al. “The Biomedical Resource Ontology (BRO) to enable resource discovery in clinical and translational research.” J Biomed Inform 44, no. 1 (February 2011): 137–45. https://doi.org/10.1016/j.jbi.2010.10.003.Full Text Link to Item
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Chan, Isaac S., and Geoffrey S. Ginsburg. “Personalized medicine: progress and promise.” Annu Rev Genomics Hum Genet 12 (2011): 217–44. https://doi.org/10.1146/annurev-genom-082410-101446.Full Text Link to Item
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Chen, Minhua, Aimee Zaas, Christopher Woods, Geoffrey S. Ginsburg, Joseph Lucas, David Dunson, and Lawrence Carin. “Predicting Viral Infection From High-Dimensional Biomarker Trajectories.” J Am Stat Assoc 106, no. 496 (January 1, 2011): 1259–79. https://doi.org/10.1198/jasa.2011.ap10611.Full Text Link to Item
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Moody, M Anthony, Ruijun Zhang, Emmanuel B. Walter, Christopher W. Woods, Geoffrey S. Ginsburg, Micah T. McClain, Thomas N. Denny, et al. “H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination.” Plos One 6, no. 10 (2011): e25797. https://doi.org/10.1371/journal.pone.0025797.Full Text Open Access Copy Link to Item
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Puig, A. T., A. Wiesel, A. K. Zaas, C. W. Woods, G. S. Ginsburg, G. Fleury, and A. O. Hero. “Order-preserving factor analysis-application to longitudinal gene expression.” Ieee Transactions on Signal Processing 59, no. 9 (January 1, 2011): 4447–58. https://doi.org/10.1109/TSP.2011.2157146.Full Text
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Puig, A. T., A. Wiesel, A. Zaas, G. S. Ginsburg, G. Fleury, and A. O. Hero. “Order-preserving factor discovery from misaligned data.” 2010 Ieee Sensor Array and Multichannel Signal Processing Workshop, Sam 2010, December 20, 2010, 209–12. https://doi.org/10.1109/SAM.2010.5606736.Full Text
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Ginsburg, G. S. “Translational Genomics. From Discovery to Clinical Practice.,” December 1, 2010, 163–74. https://doi.org/10.1016/B978-0-12-374934-5.00014-3.Full Text
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Ginsburg, G. S., and H. F. Willard. “The Foundations of Genomic and Personalized Medicine,” December 1, 2010, 1–10. https://doi.org/10.1016/B978-0-12-374934-5.00001-5.Full Text
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Voora, Deepak, Thomas L. Ortel, Joseph E. Lucas, Jen-Tsan Chi, Richard C. Becker, and Geoffrey S. Ginsburg. “A Whole Blood RNA Signature Accurately Classifies Multiple Measures of Platelet Function on Aspirin in Healthy Volunteers and Highlights a Common Underlying Pathway.” Circulation 122, no. 21 (November 23, 2010).Link to Item
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Freedman, Andrew N., Leah B. Sansbury, William D. Figg, Arnold L. Potosky, Sheila R. Weiss Smith, Muin J. Khoury, Stefanie A. Nelson, et al. “Cancer pharmacogenomics and pharmacoepidemiology: setting a research agenda to accelerate translation.” J Natl Cancer Inst 102, no. 22 (November 17, 2010): 1698–1705. https://doi.org/10.1093/jnci/djq390.Full Text Link to Item
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Chen, Bo, Minhua Chen, John Paisley, Aimee Zaas, Christopher Woods, Geoffrey S. Ginsburg, Alfred Hero, Joseph Lucas, David Dunson, and Lawrence Carin. “Bayesian inference of the number of factors in gene-expression analysis: application to human virus challenge studies.” Bmc Bioinformatics 11 (November 9, 2010): 552. https://doi.org/10.1186/1471-2105-11-552.Full Text Open Access Copy Link to Item
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Altshuler, Jill S., Erin Balogh, Anna D. Barker, Stephen L. Eck, Stephen H. Friend, Geoffrey S. Ginsburg, Roy S. Herbst, Sharyl J. Nass, Christopher M. Streeter, and John A. Wagner. “Opening up to precompetitive collaboration.” Sci Transl Med 2, no. 52 (October 6, 2010): 52cm26. https://doi.org/10.1126/scitranslmed.3001515.Full Text Link to Item
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Paisley, J., A. Zaas, C. W. Woods, G. S. Ginsburg, and L. Carin. “A stick-breaking construction of the beta process.” Icml 2010 Proceedings, 27th International Conference on Machine Learning, September 17, 2010, 847–54.
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Ginsburg, Geoffrey S., and Deepak Voora. “The long and winding road to warfarin pharmacogenetic testing.” J Am Coll Cardiol 55, no. 25 (June 22, 2010): 2813–15. https://doi.org/10.1016/j.jacc.2010.04.006.Full Text Link to Item
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Barry, William T., Dawn N. Kernagis, Holly K. Dressman, Ryan J. Griffis, J’vonne D. Hunter, John A. Olson, Jeff R. Marks, et al. “Intratumor heterogeneity and precision of microarray-based predictors of breast cancer biology and clinical outcome.” J Clin Oncol 28, no. 13 (May 1, 2010): 2198–2206. https://doi.org/10.1200/JCO.2009.26.7245.Full Text Link to Item
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Suchindran, Sunil, David Rivedal, John R. Guyton, Tom Milledge, Xiaoyi Gao, Ashlee Benjamin, Jennifer Rowell, Geoffrey S. Ginsburg, and Jeanette J. McCarthy. “Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.” Plos Genet 6, no. 4 (April 29, 2010): e1000928. https://doi.org/10.1371/journal.pgen.1000928.Full Text Open Access Copy Link to Item
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Shah, Svati H., James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, David R. Crosslin, Carol Haynes, Jennifer Dungan, et al. “Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events.” Circ Cardiovasc Genet 3, no. 2 (April 2010): 207–14. https://doi.org/10.1161/CIRCGENETICS.109.852814.Full Text Open Access Copy Link to Item
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Eagle, Kim A., Geoffrey S. Ginsburg, Kiran Musunuru, William C. Aird, Robert S. Balaban, Susan K. Bennett, Roger S. Blumenthal, et al. “Identifying patients at high risk of a cardiovascular event in the near future: current status and future directions: report of a national heart, lung, and blood institute working group.” Circulation 121, no. 12 (March 30, 2010): 1447–54. https://doi.org/10.1161/CIRCULATIONAHA.109.904029.Full Text Link to Item
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Zaas, Aimee K., Hamza Aziz, Joseph Lucas, John R. Perfect, and Geoffrey S. Ginsburg. “Blood gene expression signatures predict invasive candidiasis.” Sci Transl Med 2, no. 21 (March 3, 2010): 21ra17. https://doi.org/10.1126/scitranslmed.3000715.Full Text Link to Item
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Tsalik, Ephraim L., Edward F. Hendershot, Devdutta G. Sangvai, Hannah M. Cunningham, Coleen K. Cunningham, Maria G. Lopez-Marti, William K. Purdy, Christopher W. Woods, and L Brett Caram. “Clinical presentation and response to treatment of novel influenza A H1N1 in a university-based summer camp population.” J Clin Virol 47, no. 3 (March 2010): 286–88. https://doi.org/10.1016/j.jcv.2009.12.012.Full Text Link to Item
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Zaas, A. K., M. Chen, A. O. Hero, J. Lucas, L. Carin, and G. S. Ginsburg. “Response: Improving Development of the Molecular Signature for Diagnosis of Acute Respiratory Viral Infections.” Cell Host and Microbe 7, no. 2 (February 18, 2010): 102. https://doi.org/10.1016/j.chom.2010.02.002.Full Text
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Kutty, Preeta K., Christopher W. Woods, Arlene C. Sena, Stephen R. Benoit, Susanna Naggie, Joyce Frederick, Sharon Evans, Jeffery Engel, and L Clifford McDonald. “Risk factors for and estimated incidence of community-associated Clostridium difficile infection, North Carolina, USA.” Emerg Infect Dis 16, no. 2 (February 2010): 197–204. https://doi.org/10.3201/eid1602.090953.Full Text Open Access Copy Link to Item
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Chiba-Falek, Ornit, Marshall Nichols, Sunil Suchindran, John Guyton, Geoffrey S. Ginsburg, Elizabeth Barrett-Connor, and Jeanette J. McCarthy. “Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study.” Bmc Med Genet 11 (January 19, 2010): 9. https://doi.org/10.1186/1471-2350-11-9.Full Text Open Access Copy Link to Item
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Ginsburg, G. S. “Translational Genomics: From Discovery to Clinical Practice,” December 1, 2009, 242–51. https://doi.org/10.1016/B978-0-12-369420-1.00022-6.Full Text
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Ginsburg, G. S., and H. F. Willard. “Genomic and Personalized Medicine, Two-Vol Set.” Genomic and Personalized Medicine, Two Vol Set, December 1, 2009.
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Ginsburg, Geoffrey S., and Huntington F. Willard. “Genomic and personalized medicine: foundations and applications.” Transl Res 154, no. 6 (December 2009): 277–87. https://doi.org/10.1016/j.trsl.2009.09.005.Full Text Link to Item
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Lendlein, A., V. P. Shastri, and K. Gall. “Preface.” Materials Research Society Symposium Proceedings 1190 (December 1, 2009).
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Voora, D., and G. S. Ginsburg. “Pharmacogenetics of the response to statins.” Current Cardiovascular Risk Reports 3, no. 6 (December 1, 2009): 434–40. https://doi.org/10.1007/s12170-009-0064-1.Full Text
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Kawamoto, Kensaku, Lori A. Orlando, Deepak Voora, David F. Lobach, Scott Joy, Alex Cho, and Geoffrey S. Ginsburg. “Evaluation of the PharmGKB knowledge base as a resource for efficiently assessing the clinical validity and utility of pharmacogenetic assays.” Amia Annu Symp Proc 2009 (November 14, 2009): 307–11.Link to Item
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Voora, Deepak, Svati H. Shah, Ivan Spasojevic, Shazia Ali, Carol R. Reed, Benjamin A. Salisbury, and Geoffrey S. Ginsburg. “The SLCO1B1*5 genetic variant is associated with statin-induced side effects.” J Am Coll Cardiol 54, no. 17 (October 20, 2009): 1609–16. https://doi.org/10.1016/j.jacc.2009.04.053.Full Text Link to Item
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Zaas, Aimee K., Minhua Chen, Jay Varkey, Timothy Veldman, Alfred O. Hero, Joseph Lucas, Yongsheng Huang, et al. “Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans.” Cell Host Microbe 6, no. 3 (September 17, 2009): 207–17. https://doi.org/10.1016/j.chom.2009.07.006.Full Text Link to Item
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Sinnaeve, Peter R., Mark P. Donahue, Peter Grass, David Seo, Jacky Vonderscher, Salah-Dine Chibout, William E. Kraus, et al. “Gene expression patterns in peripheral blood correlate with the extent of coronary artery disease.” Plos One 4, no. 9 (September 14, 2009): e7037. https://doi.org/10.1371/journal.pone.0007037.Full Text Link to Item
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Khoury, Muin J., Colleen M. McBride, Sheri D. Schully, John P. A. Ioannidis, W Gregory Feero, A Cecile J. W. Janssens, Marta Gwinn, et al. “The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop.” Genet Med 11, no. 8 (August 2009): 559–67. https://doi.org/10.1097/GIM.0b013e3181b13a6c.Full Text Link to Item
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Ginsburg, G. “Genomic and Personalized Medicine: Happening now.” Personalized Medicine 6, no. 1 (July 29, 2009): 15–18. https://doi.org/10.2217/17410541.6.1.15.Full Text
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Wingrove, James A., Michael Elashoff, Whittemore G. Tingley, Amy J. Sehnert, Susan E. Daniels, Steven Rosenberg, William E. Kraus, L. K. Newby, and Geoffrey S. Ginsburg. “Development and Validation of a Peripheral Blood-Based Gene Expression Algorithm for the Detection of Coronary Artery Disease (CAD).” Arteriosclerosis Thrombosis and Vascular Biology 29, no. 7 (July 1, 2009): E24–E24.Link to Item
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Broadfoot, Marla Vacek, and Geoffrey S. Ginsburg. “The Center for Genomic Medicine at the Duke Institute for Genome Sciences & Policy: propelling genomics into clinical practice.” Per Med 6, no. 3 (May 2009): 255–61. https://doi.org/10.2217/pme.09.9.Full Text Link to Item
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Kawamoto, Kensaku, David F. Lobach, Huntington F. Willard, and Geoffrey S. Ginsburg. “A national clinical decision support infrastructure to enable the widespread and consistent practice of genomic and personalized medicine.” Bmc Med Inform Decis Mak 9 (March 23, 2009): 17. https://doi.org/10.1186/1472-6947-9-17.Full Text Link to Item
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Burt, T. P., and R. J. Allison. “Sediment Cascades: An Integrated Approach.” Sediment Cascades: An Integrated Approach, January 1, 2009, 1–471. https://doi.org/10.1002/9780470682876.Full Text
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Garman, K. S., C. R. Acharya, E. Edelman, M. Grade, J. Gaedcke, S. Sud, W. Barry, et al. “Erratum: A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities (Proceedings of the National Academy of Sciences of the United States of America (2008) 105:49 (19432-19437) Doi: 10.1073/pnas.0806674105).” Proceedings of the National Academy of Sciences of the United States of America 106, no. 16 (2009): 6878-. https://doi.org/10.1073/pnas.0902004106.Full Text
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Ginsburg, Geoffrey S., and Jeanette J McCarthy. “Transforming the practice of medicine using genomics.” Clin Cases Miner Bone Metab 6, no. 1 (January 2009): 25–28.Link to Item
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Shah, Svati H., Elizabeth R. Hauser, James R. Bain, Michael J. Muehlbauer, Carol Haynes, Robert D. Stevens, Brett R. Wenner, et al. “High heritability of metabolomic profiles in families burdened with premature cardiovascular disease.” Mol Syst Biol 5 (2009): 258. https://doi.org/10.1038/msb.2009.11.Full Text Link to Item
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Shah, Svati H., Neil J. Freedman, Lisheng Zhang, David R. Crosslin, David H. Stone, Carol Haynes, Jessica Johnson, et al. “Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis.” Plos Genet 5, no. 1 (January 2009): e1000318. https://doi.org/10.1371/journal.pgen.1000318.Full Text Open Access Copy Link to Item
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Willard, H. F., and G. S. Ginsburg. “Preface.” Genomic and Personalized Medicine, Two Vol Set, January 1, 2009. https://doi.org/10.1016/b978-0-12-369420-1.00114-1.Full Text
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Garman, Katherine S., Chaitanya R. Acharya, Elena Edelman, Marian Grade, Jochen Gaedcke, Shivani Sud, William Barry, et al. “A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities.” Proc Natl Acad Sci U S A 105, no. 49 (December 9, 2008): 19432–37. https://doi.org/10.1073/pnas.0806674105.Full Text Link to Item
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Voora, Deepak, Svati H. Shah, Carol R. Reed, Jun Zhai, David R. Crosslin, Chad Messer, Benjamin A. Salisbury, and Geoffrey S. Ginsburg. “Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response.” Circ Cardiovasc Genet 1, no. 2 (December 2008): 100–106. https://doi.org/10.1161/CIRCGENETICS.108.795013.Full Text Link to Item
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Califf, Robert M., and Geoffrey S. Ginsburg. “Organizational improvements to enhance modern clinical epidemiology.” Jama 300, no. 19 (November 19, 2008): 2300–2302. https://doi.org/10.1001/jama.2008.638.Full Text Link to Item
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Voora, Deepak, Shazia Ali, Svati H. Shah, Carol R. Reed, Benjamin Salisbury, and Geoffrey S. Ginsburg. “Association of Statin-Induced Musculoskeletal Side Effects with Sex and a Hepatic Uptake Transporter Reduced Function Allele, SLC01B1*5.” Circulation 118, no. 18 (October 28, 2008): S326–S326.Link to Item
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Wingrove, James A., Michael Elashoff, Whittemore G. Tingley, Amy J. Sehnert, Susan E. Daniels, Nicholas F. Paoni, Steven Rosenberg, William E. Kraus, L. K. Newby, and Geoffrey S. Ginsburg. “Discovery of Genes Expressed in Whole Blood which Identity Patients with Coronary Artery Disease.” Circulation 118, no. 18 (October 28, 2008): S389–S389.Link to Item
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Wingrove, James A., Susan E. Daniels, Amy J. Sehnert, Whittemore Tingley, Michael R. Elashoff, Steven Rosenberg, Lutz Buellesfeld, et al. “Correlation of peripheral-blood gene expression with the extent of coronary artery stenosis.” Circ Cardiovasc Genet 1, no. 1 (October 2008): 31–38. https://doi.org/10.1161/CIRCGENETICS.108.782730.Full Text Link to Item
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Ginsburg, Geoffrey S. “Genomic Medicine: 'grand challenges' in the translation of genomics to human health.” Eur J Hum Genet 16, no. 8 (August 2008): 873–74. https://doi.org/10.1038/ejhg.2008.115.Full Text Link to Item
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Glickman, Seth W., Kevin J. Anstrom, Li Lin, Abhinav Chandra, Daniel T. Laskowitz, Christopher W. Woods, Debra H. Freeman, et al. “Challenges in enrollment of minority, pediatric, and geriatric patients in emergency and acute care clinical research.” Ann Emerg Med 51, no. 6 (June 2008): 775-780.e3. https://doi.org/10.1016/j.annemergmed.2007.11.002.Full Text Link to Item
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Acharya, Chaitanya R., David S. Hsu, Carey K. Anders, Ariel Anguiano, Kelly H. Salter, Kelli S. Walters, Richard C. Redman, et al. “Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer.” Jama 299, no. 13 (April 2, 2008): 1574–87. https://doi.org/10.1001/jama.299.13.1574.Full Text Link to Item
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Meadows, Sarah K., Holly K. Dressman, Garrett G. Muramoto, Heather Himburg, Alice Salter, ZhengZheng Wei, Geoffrey S. Ginsburg, Nelson J. Chao, Joseph R. Nevins, and John P. Chute. “Gene expression signatures of radiation response are specific, durable and accurate in mice and humans.” Plos One 3, no. 4 (April 2, 2008): e1912. https://doi.org/10.1371/journal.pone.0001912.Full Text Open Access Copy Link to Item
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Ginsburg, Geoffrey S., Thomas W. Burke, and Phillip Febbo. “Centralized biorepositories for genetic and genomic research.” Jama 299, no. 11 (March 19, 2008): 1359–61. https://doi.org/10.1001/jama.299.11.1359.Full Text Link to Item
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Douglas, Pamela S., and Geoffrey S. Ginsburg. “Clinical genomic testing: getting it right.” J Cardiovasc Transl Res 1, no. 1 (March 2008): 17–20. https://doi.org/10.1007/s12265-007-9004-y.Full Text Link to Item
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DeMaria, Anthony N., Jeroen J. Bax, Ori Ben-Yehuda, Paul Clopton, Gregory K. Feld, Geoffrey S. Ginsburg, Barry H. Greenberg, et al. “Highlights of the year in JACC 2007.” J Am Coll Cardiol 51, no. 4 (January 29, 2008): 490–512. https://doi.org/10.1016/j.jacc.2007.12.003.Full Text Link to Item
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Ginsburg, Geoffrey S. “Regression of atherosclerosis with therapeutic antibodies pipe cleaner or pipe dream?” J Am Coll Cardiol 50, no. 24 (December 11, 2007): 2319–21. https://doi.org/10.1016/j.jacc.2007.08.039.Full Text Link to Item
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Lugogo, Njira L., Geoffrey S. Ginsburg, and Loretta G. Que. “Genetic profiling and tailored therapy in asthma: are we there yet?” Curr Opin Mol Ther 9, no. 6 (December 2007): 528–37.Link to Item
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Potti, A., H. K. Dressman, A. Bild, R. F. Riedel, G. Chan, R. Sayer, J. Cragun, et al. “Corrigenda: Genomic signatures to guide the use of chemotherapeutics.” Nature Medicine 13, no. 11 (November 2007): 1388.
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Shadick, N. A., J. E. Heller, M. E. Weinblatt, N. E. Maher, J. Cui, G. Ginsburg, J. Coblyn, et al. “Opposing effects of the D70 mutation and the shared epitope in HLA-DR4 on disease activity and certain disease phenotypes in rheumatoid arthritis.” Ann Rheum Dis 66, no. 11 (November 2007): 1497–1502. https://doi.org/10.1136/ard.2006.067603.Full Text Link to Item
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Voora, Deepalk, Carol R. Reed, Jun Zhai, Benjamin A. Salisbury, Svatj H. Shah, and Geoffrey S. Ginsburg. “Polymorphisms in ABCA1 predict statin mediated LDL cholesterol lowering and suggest an interaction with CETP.” Circulation 116, no. 16 (October 16, 2007): 178–178.Link to Item
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Ginsburg, Geoffrey S., Svati H. Shah, and Jeanette J. McCarthy. “Taking cardiovascular genetic association studies to the next level.” J Am Coll Cardiol 50, no. 10 (September 4, 2007): 930–32. https://doi.org/10.1016/j.jacc.2007.05.025.Full Text Link to Item
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Parker, Alex, Elena S. Izmailova, Jigna Narang, Sunita Badola, Tinh Le, Ronenn Roubenoff, Geoffrey S. Ginsburg, et al. “Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate.” J Rheumatol 34, no. 9 (September 2007): 1817–22.Link to Item
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Dressman, Holly K., Garrett G. Muramoto, Nelson J. Chao, Sarah Meadows, Dawn Marshall, Geoffrey S. Ginsburg, Joseph R. Nevins, and John P. Chute. “Gene expression signatures that predict radiation exposure in mice and humans.” Plos Med 4, no. 4 (April 2007): e106. https://doi.org/10.1371/journal.pmed.0040106.Full Text Open Access Copy Link to Item
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Luo, Albert K., Brian K. Jefferson, Mario J. Garcia, Geoffrey S. Ginsburg, and Eric J. Topol. “Challenges in the phenotypic characterisation of patients in genetic studies of coronary artery disease.” J Med Genet 44, no. 3 (March 2007): 161–65. https://doi.org/10.1136/jmg.2006.045732.Full Text Link to Item
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DeMaria, Anthony N., Ori Ben-Yehuda, Gregory K. Feld, Geoffrey S. Ginsburg, Barry H. Greenberg, Wilbur Y. W. Lew, Joao A. C. Lima, et al. “Highlights of the Year in JACC 2006.” J Am Coll Cardiol 49, no. 4 (January 30, 2007): 509–27. https://doi.org/10.1016/j.jacc.2006.12.008.Full Text Link to Item
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Aziz, Hamza, Aimee Zaas, and Geoffrey S. Ginsburg. “Peripheral blood gene expression profiling for cardiovascular disease assessment.” Genomic Med 1, no. 3–4 (2007): 105–12. https://doi.org/10.1007/s11568-008-9017-x.Full Text Link to Item
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Ginsburg, G. S. “Erratum: Genomics and medicine at a crossroads in chernobyl (Science (62)).” Science 314, no. 5806 (December 15, 2006): 1683.
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Ginsburg, Geoffrey S., David Seo, and Camille Frazier. “Microarrays coming of age in cardiovascular medicine: standards, predictions, and biology.” J Am Coll Cardiol 48, no. 8 (October 17, 2006): 1618–20. https://doi.org/10.1016/j.jacc.2006.07.025.Full Text Link to Item
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Ginsburg, Geoffrey S., Misha Angrist, and Robert Cook-Deegan. “Public health. Genomics and medicine at a crossroads in Chernobyl.” Science 314, no. 5796 (October 6, 2006): 62–63. https://doi.org/10.1126/science.1130274.Full Text Link to Item
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Freedman, Neil J., and Geoffrey S. Ginsburg. “Novel--and "neu"--therapeutic possibilities for heart failure.” J Am Coll Cardiol 48, no. 7 (October 3, 2006): 1448–50. https://doi.org/10.1016/j.jacc.2006.07.005.Full Text Link to Item
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Stallings, Sarah C., Dan Huse, Stan N. Finkelstein, William H. Crown, Whitney P. Witt, Jon Maguire, Arthur J. Hiller, Anthony J. Sinskey, and Geoffrey S. Ginsburg. “A framework to evaluate the economic impact of pharmacogenomics.” Pharmacogenomics 7, no. 6 (September 2006): 853–62. https://doi.org/10.2217/14622416.7.6.853.Full Text Link to Item
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Potti, Anil, Sayan Mukherjee, Rebecca Petersen, Holly K. Dressman, Andrea Bild, Jason Koontz, Robert Kratzke, et al. “A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer.” N Engl J Med 355, no. 6 (August 10, 2006): 570–80. https://doi.org/10.1056/NEJMoa060467.Full Text Link to Item
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Seo, David, Geoffrey S. Ginsburg, and Pascal J. Goldschmidt-Clermont. “Gene expression analysis of cardiovascular diseases: novel insights into biology and clinical applications.” J Am Coll Cardiol 48, no. 2 (July 18, 2006): 227–35. https://doi.org/10.1016/j.jacc.2006.02.070.Full Text Link to Item
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Haga, Susanne B., and Geoffrey S. Ginsburg. “Prescribing BiDil: is it black and white?” J Am Coll Cardiol 48, no. 1 (July 4, 2006): 12–14. https://doi.org/10.1016/j.jacc.2006.04.017.Full Text Link to Item
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Brooks, Richard, Christopher W. Woods, Daniel K. Benjamin, and Nancy E. Rosenstein. “Increased case-fatality rate associated with outbreaks of Neisseria meningitidis infection, compared with sporadic meningococcal disease, in the United States, 1994-2002.” Clin Infect Dis 43, no. 1 (July 1, 2006): 49–54. https://doi.org/10.1086/504804.Full Text Link to Item
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Cotten, C Michael, Geoffrey S. Ginsburg, Ronald N. Goldberg, and Marcy C. Speer. “Genomic analyses: a neonatology perspective.” J Pediatr 148, no. 6 (June 2006): 720–26. https://doi.org/10.1016/j.jpeds.2006.01.006.Full Text Link to Item
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Lalani, T., Z. A. Kanafani, V. H. Chu, L. Moore, G. R. Corey, P. Pappas, C. W. Woods, et al. “Prosthetic valve endocarditis due to coagulase-negative staphylococci: findings from the International Collaboration on Endocarditis Merged Database.” Eur J Clin Microbiol Infect Dis 25, no. 6 (June 2006): 365–68. https://doi.org/10.1007/s10096-006-0141-z.Full Text Link to Item
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Ginsburg, Geoffrey S., and Misha Angrist. “The future may be closer than you think: a response from the Personalized Medicine Coalition to the Royal Society's report on personalized medicine.” Per Med 3, no. 2 (May 2006): 119–23. https://doi.org/10.2217/17410541.3.2.119.Full Text Link to Item
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Pien, Brian C., J Royden Saah, Sara E. Miller, and Christopher W. Woods. “Use of sentinel laboratories by clinicians to evaluate potential bioterrorism and emerging infections.” Clin Infect Dis 42, no. 9 (May 1, 2006): 1311–24. https://doi.org/10.1086/503260.Full Text Link to Item
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West, Mike, Geoffrey S. Ginsburg, Andrew T. Huang, and Joseph R. Nevins. “Embracing the complexity of genomic data for personalized medicine.” Genome Res 16, no. 5 (May 2006): 559–66. https://doi.org/10.1101/gr.3851306.Full Text Link to Item
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Ginsburg, Geoffrey S., and Susanne B. Haga. “Translating genomic biomarkers into clinically useful diagnostics.” Expert Rev Mol Diagn 6, no. 2 (March 2006): 179–91. https://doi.org/10.1586/14737159.6.2.179.Full Text Link to Item
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Demaria, Anthony N., Ori Ben-Yehuda, Daniel Berman, Gregory K. Feld, Jeffrey Ginsberg, Barry H. Greenberg, Wilbur Y. W. Lew, David Sahn, and Sotirios Tsimikas. “Highlights of the Year in JACC 2005.” J Am Coll Cardiol 47, no. 1 (January 3, 2006): 184–202. https://doi.org/10.1016/j.jacc.2005.11.020.Full Text Link to Item
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Ginsburg, Geoffrey S., Richard P. Konstance, Jennifer S. Allsbrook, and Kevin A. Schulman. “Implications of pharmacogenomics for drug development and clinical practice.” Arch Intern Med 165, no. 20 (November 14, 2005): 2331–36. https://doi.org/10.1001/archinte.165.20.2331.Full Text Link to Item
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Ginsburg, Geoffrey S., Mark P. Donahue, and L Kristin Newby. “Prospects for personalized cardiovascular medicine: the impact of genomics.” J Am Coll Cardiol 46, no. 9 (November 1, 2005): 1615–27. https://doi.org/10.1016/j.jacc.2005.06.075.Full Text Link to Item
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Willard, Huntington F., Misha Angrist, and Geoffrey S. Ginsburg. “Genomic medicine: genetic variation and its impact on the future of health care.” Philos Trans R Soc Lond B Biol Sci 360, no. 1460 (August 29, 2005): 1543–50. https://doi.org/10.1098/rstb.2005.1683.Full Text Link to Item
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Seo, David, and Geoffrey S. Ginsburg. “Genomic medicine: bringing biomarkers to clinical medicine.” Curr Opin Chem Biol 9, no. 4 (August 2005): 381–86. https://doi.org/10.1016/j.cbpa.2005.06.009.Full Text Link to Item
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Jefferson, Brian K., Jennifer H. Foster, Jeanette J. McCarthy, Geoffrey Ginsburg, Alex Parker, Kandice Kottke-Marchant, and Eric J. Topol. “Aspirin resistance and a single gene.” Am J Cardiol 95, no. 6 (March 15, 2005): 805–8. https://doi.org/10.1016/j.amjcard.2004.11.045.Full Text Link to Item
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Abrahams, Edward, Geoffrey S. Ginsburg, and Mike Silver. “The Personalized Medicine Coalition: goals and strategies.” Am J Pharmacogenomics 5, no. 6 (2005): 345–55. https://doi.org/10.2165/00129785-200505060-00002.Full Text Link to Item
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Ross, Jeffrey S., David P. Schenkein, Robert Pietrusko, Mark Rolfe, Gerald P. Linette, James Stec, Nancy E. Stagliano, et al. “Targeted therapies for cancer 2004.” Am J Clin Pathol 122, no. 4 (October 2004): 598–609. https://doi.org/10.1309/5CWP-U41A-FR1V-YM3F.Full Text Link to Item
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Ivanov, Gleb S., Jessie M. Kater, Shivkumar H. Jha, Erica A. Stutius, Ravleen Sabharwal, Marisa D. Tricarico, Geoffrey S. Ginsburg, and Josef S. Ozer. “Sp and GATA factors are critical for Apolipoprotein AI downstream enhancer activity in human HepG2 cells.” Gene 323 (December 24, 2003): 31–42. https://doi.org/10.1016/j.gene.2003.08.014.Full Text Link to Item
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Ross, Jeffrey S., and Geoffrey S. Ginsburg. “The integration of molecular diagnostics with therapeutics. Implications for drug development and pathology practice.” Am J Clin Pathol 119, no. 1 (January 2003): 26–36. https://doi.org/10.1309/VMLL-66Y5-KHQ3-5KUE.Full Text Link to Item
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Loscalzo, Joseph, Robert Balaban, Lance B. Becker, Geoffrey S. Ginsburg, Vladimir C. Hachinski, John E. Hall, Donald D. Heistad, et al. “Task Force on Strategic Research Direction: Basic Science Subgroup key science topics report.” Circulation 106, no. 20 (November 12, 2002): e149–61. https://doi.org/10.1161/01.cir.0000040842.08331.4e.Full Text Link to Item
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Ross, Jeffrey S., and Geoffrey S. Ginsburg. “Integration of molecular diagnostics with therapeutics: implications for drug discovery and patient care.” Expert Rev Mol Diagn 2, no. 6 (November 2002): 531–41. https://doi.org/10.1586/14737159.2.6.531.Full Text Link to Item
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Ross, Jeffrey S., and Geoffrey S. Ginsburg. “Integrating diagnostics and therapeutics: revolutionizing drug discovery and patient care.” Drug Discov Today 7, no. 16 (August 15, 2002): 859–64. https://doi.org/10.1016/s1359-6446(02)02405-4.Full Text Link to Item
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Meyer, Joanne M., and Geoffrey S. Ginsburg. “The path to personalized medicine.” Curr Opin Chem Biol 6, no. 4 (August 2002): 434–38. https://doi.org/10.1016/s1367-5931(02)00340-x.Full Text Link to Item
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Ginsburg, G. S., and J. J. McCarthy. “Personalized medicine: revolutionizing drug discovery and patient care.” Trends Biotechnol 19, no. 12 (December 2001): 491–96. https://doi.org/10.1016/s0167-7799(01)01814-5.Full Text Link to Item
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Ross, J. S., N. E. Stagliano, M. J. Donovan, R. E. Breitbart, and G. S. Ginsburg. “Atherosclerosis: a cancer of the blood vessels?” Am J Clin Pathol 116 Suppl (December 2001): S97-107. https://doi.org/10.1309/YNCK-9R19-5JA3-K2K9.Full Text Link to Item
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Ross, J. S., N. E. Stagliano, M. J. Donovan, R. E. Breitbart, and G. S. Ginsburg. “Atherosclerosis and cancer: common molecular pathways of disease development and progression.” Ann N Y Acad Sci 947 (December 2001): 271–92.Link to Item
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Ginsburg, G. S., M. O’Toole, E. Rimm, P. S. Douglas, and N. Rifai. “Gender differences in exercise-induced changes in sex hormone levels and lipid peroxidation in athletes participating in the Hawaii Ironman triathlon. Ginsburg-gender and exercise-induced lipid peroxidation.” Clin Chim Acta 305, no. 1–2 (March 2001): 131–39. https://doi.org/10.1016/s0009-8981(00)00427-7.Full Text Link to Item
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Yu, H. H., R. C. Pasternak, and G. S. Ginsburg. “Dyslipidemia in patients with CAD: Rational use of diets and drugs.” Consultant 40, no. 10 (September 1, 2000): 1762–72.
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Ginsburg, G. S., and W. K. Silverman. “Gender role orientation and fearfulness in children with anxiety disorders.” J Anxiety Disord 14, no. 1 (January 2000): 57–67. https://doi.org/10.1016/s0887-6185(99)00033-x.Full Text Link to Item
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Yu, H. H., R. C. Pasternak, and G. S. Ginsburg. “Lipid management for patients with CAD, Part 2: A guide to drug therapy.” Journal of Critical Illness 15, no. 6 (January 1, 2000): 302–15.
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Yu, H. H., R. C. Pasternak, and G. S. Ginsburg. “Lipid management for patients with CAD, Part 1: What to expect, when to start. Consider an aggressive strategy for prevention of cardiac events.” Journal of Critical Illness 15, no. 5 (January 1, 2000): 247–64.
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Yu, H. H., R. C. Pasternak, and G. S. Ginsburg. “Dyslipidemia in patients with CAD: How to make best use of drug therapy.” Consultant 40, no. 12 (January 1, 2000): 2097–2109.
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Yu, H. H., G. S. Ginsburg, M. L. O’Toole, J. D. Otvos, P. S. Douglas, and N. Rifai. “Acute changes in serum lipids and lipoprotein subclasses in triathletes as assessed by proton nuclear magnetic resonance spectroscopy.” Arterioscler Thromb Vasc Biol 19, no. 8 (August 1999): 1945–49. https://doi.org/10.1161/01.atv.19.8.1945.Full Text Link to Item
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Gauthier, B., M. Robb, F. Gaudet, G. S. Ginsburg, and R. McPherson. “Characterization of a cholesterol response element (CRE) in the promoter of the cholesteryl ester transfer protein gene: functional role of the transcription factors SREBP-1a, -2, and YY1.” J Lipid Res 40, no. 7 (July 1999): 1284–93.Link to Item
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Rifai, N., P. S. Douglas, M. O’Toole, E. Rimm, and G. S. Ginsburg. “Cardiac troponin T and I, echocardiographic [correction of electrocardiographic] wall motion analyses, and ejection fractions in athletes participating in the Hawaii Ironman Triathlon.” Am J Cardiol 83, no. 7 (April 1, 1999): 1085–89. https://doi.org/10.1016/s0002-9149(99)00020-x.Full Text Link to Item
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Satler, C. A., M. R. Vesely, P. Duggal, G. S. Ginsburg, and A. H. Beggs. “Multiple different missense mutations in the pore region of HERG in patients with long QT syndrome.” Hum Genet 102, no. 3 (March 1998): 265–72. https://doi.org/10.1007/s004390050690.Full Text Link to Item
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Douglas, P. S., M. L. O’Toole, S. E. Katz, G. S. Ginsburg, W. D. Hiller, and R. H. Laird. “Left ventricular hypertrophy in athletes.” Am J Cardiol 80, no. 10 (November 15, 1997): 1384–88. https://doi.org/10.1016/s0002-9149(97)00693-0.Full Text Link to Item
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Yu, H. H., G. S. Ginsburg, N. Harris, and N. Rifai. “Evaluation and clinical application of a direct low-density lipoprotein cholesterol assay in normolipidemic and hyperlipidemic adults.” Am J Cardiol 80, no. 10 (November 15, 1997): 1295–99. https://doi.org/10.1016/s0002-9149(97)00668-1.Full Text Link to Item
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Joffe, I. I., M. F. Riley, S. E. Katz, G. S. Ginsburg, and P. S. Douglas. “Acquired dynamic left ventricular outflow tract obstruction complicating acute anterior myocardial infarction: serial echocardiographic and clinical evaluation.” J Am Soc Echocardiogr 10, no. 7 (September 1997): 717–21. https://doi.org/10.1016/s0894-7317(97)70114-7.Full Text Link to Item
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Naganawa, S., H. N. Ginsberg, R. M. Glickman, and G. S. Ginsburg. “Intestinal transcription and synthesis of apolipoprotein AI is regulated by five natural polymorphisms upstream of the apolipoprotein CIII gene.” J Clin Invest 99, no. 8 (April 15, 1997): 1958–65. https://doi.org/10.1172/JCI119363.Full Text Link to Item
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Satler, C. A., E. P. Walsh, M. R. Vesely, M. H. Plummer, G. S. Ginsburg, and H. J. Jacob. “Novel missense mutation in the cyclic nucleotide-binding domain of HERG causes long QT syndrome.” American Journal of Medical Genetics 65, no. 1 (October 2, 1996): 27–35. https://doi.org/10.1002/(SICI)1096-8628(19961002)65:1<27::AID-AJMG4>3.0.CO;2-V.Full Text
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Satler, C. A., E. P. Walsh, M. R. Vesely, M. H. Plummer, G. S. Ginsburg, and H. J. Jacob. “Novel missense mutation in the cyclic nucleotide-binding domain of HERG causes long QT syndrome.” Am J Med Genet 65, no. 1 (October 2, 1996): 27–35. https://doi.org/10.1002/(SICI)1096-8628(19961002)65:1<27::AID-AJMG4>3.0.CO;2-V.Full Text Link to Item
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Auerbach, I., P. Chouraqui, and M. Motro. “Chest pain in women.” N Engl J Med 335, no. 11 (September 12, 1996): 820. https://doi.org/10.1056/NEJM199609123351113.Full Text Link to Item
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Ginsburg, G. S., and P. S. Douglas. “Why cardiologists should be interested in estrogen.” Am J Cardiol 78, no. 5 (September 1, 1996): 559–61. https://doi.org/10.1016/s0002-9149(96)00365-7.Full Text Link to Item
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Harris, N., E. J. Neufeld, J. W. Newburger, B. Ticho, A. Baker, G. S. Ginsburg, E. Rimm, and N. Rifai. “Analytical performance and clinical utility of a direct LDL-cholesterol assay in a hyperlipidemic pediatric population.” Clin Chem 42, no. 8 Pt 1 (August 1996): 1182–88.Link to Item
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Ginsburg, G. S., A. Agil, M. O’Toole, E. Rimm, P. S. Douglas, and N. Rifai. “Effects of a single bout of ultraendurance exercise on lipid levels and susceptibility of lipids to peroxidation in triathletes.” Jama 276, no. 3 (July 17, 1996): 221–25.Link to Item
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Douglas, P. S., and G. S. Ginsburg. “The evaluation of chest pain in women.” N Engl J Med 334, no. 20 (May 16, 1996): 1311–15. https://doi.org/10.1056/NEJM199605163342007.Full Text Link to Item
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Harris, N., E. J. Neufeld, J. W. Newburger, B. Ticho, A. Baker, G. S. Ginsburg, E. Rimm, and N. Rifai. “Analytical performance and clinical utility of a direct LDL-cholesterol assay in a hyperlipidemic pediatric population.” Clinical Chemistry 42, no. 8 (January 1, 1996): 1182–88. https://doi.org/10.1093/clinchem/42.8.1182.Full Text
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Gaudet, F., and G. S. Ginsburg. “Transcriptional regulation of the cholesteryl ester transfer protein gene by the orphan nuclear hormone receptor apolipoprotein AI regulatory protein-1.” J Biol Chem 270, no. 50 (December 15, 1995): 29916–22. https://doi.org/10.1074/jbc.270.50.29916.Full Text Link to Item
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Ginsburg, G. S., J. Ozer, and S. K. Karathanasis. “Intestinal apolipoprotein AI gene transcription is regulated by multiple distinct DNA elements and is synergistically activated by the orphan nuclear receptor, hepatocyte nuclear factor 4.” J Clin Invest 96, no. 1 (July 1995): 528–38. https://doi.org/10.1172/JCI118065.Full Text Link to Item
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Leidig, G. A., R. C. Pasternak, G. Horowitz, and G. S. Ginsburg. “Effects of heparin and cardiac catheterization on serum lipoprotein and triglyceride levels.” Am J Cardiol 74, no. 1 (July 1, 1994): 47–52. https://doi.org/10.1016/0002-9149(94)90490-1.Full Text Link to Item
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Oettgen, P., G. S. Ginsburg, G. L. Horowitz, and R. C. Pasternak. “Frequency of hypothyroidism in adults with serum total cholesterol levels > 200 mg/dl.” Am J Cardiol 73, no. 13 (May 15, 1994): 955–57. https://doi.org/10.1016/0002-9149(94)90138-4.Full Text Link to Item
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Silverman, D. I., G. S. Ginsburg, and R. C. Pasternak. “High-density lipoprotein subfractions.” Am J Med 94, no. 6 (June 1993): 636–45. https://doi.org/10.1016/0002-9343(93)90217-d.Full Text Link to Item
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Mietus-Snyder, M., F. M. Sladek, G. S. Ginsburg, C. F. Kuo, J. A. Ladias, J. E. Darnell, and S. K. Karathanasis. “Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells.” Mol Cell Biol 12, no. 4 (April 1992): 1708–18. https://doi.org/10.1128/mcb.12.4.1708-1718.1992.Full Text Link to Item
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Ginsburg, G. S., and R. C. Pasternak. “Coronary artery disease risk when total cholesterol levels are desirable.” Cardiology Board Review 9, no. 5 (January 1, 1992): 83-84+89.
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Ginsburg, G. S., C. Safran, and R. C. Pasternak. “Frequency of low serum high-density lipoprotein cholesterol levels in hospitalized patients with "desirable" total cholesterol levels.” Am J Cardiol 68, no. 2 (July 15, 1991): 187–92. https://doi.org/10.1016/0002-9149(91)90742-4.Full Text Link to Item
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Ginsburg, G. S., M. T. Walsh, D. M. Small, and D. Atkinson. “Reassembled plasma low density lipoproteins. Phospholipid-cholesterol ester-apoprotein B complexes.” J Biol Chem 259, no. 10 (May 25, 1984): 6667–73.Link to Item
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Ginsburg, G. S., D. Atkinson, and D. M. Small. “Physical properties of cholesteryl esters.” Prog Lipid Res 23, no. 3 (1984): 135–67. https://doi.org/10.1016/0163-7827(84)90002-x.Full Text Link to Item
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Ginsburg, G. S., D. M. Small, and J. A. Hamilton. “Temperature-dependent molecular motions of cholesterol esters: a carbon-13 nuclear magnetic resonance study.” Biochemistry 21, no. 26 (December 21, 1982): 6857–67. https://doi.org/10.1021/bi00269a036.Full Text Link to Item
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Ginsburg, G. S., D. M. Small, and D. Atkinson. “Microemulsions of phospholipids and cholesterol esters. Protein-free models of low density lipoprotein.” J Biol Chem 257, no. 14 (July 25, 1982): 8216–27.Link to Item
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Ginsburg, G. S., and D. M. Small. “Physical properties of cholesteryl esters having 20 carbons or more.” Biochim Biophys Acta 664, no. 1 (April 23, 1981): 98–107. https://doi.org/10.1016/0005-2760(81)90032-1.Full Text Link to Item
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Fry, A. J., and G. S. Ginsburg. “Stereoelectronic Control in the Electrochemical and Mercury-Promoted Reductive Acetoxylation of α,α’-Dibromobicycloalkanones.” Journal of the American Chemical Society 101, no. 14 (July 1, 1979): 3927–32. https://doi.org/10.1021/ja00508a034.Full Text
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Fry, A. J., and G. S. Ginsburg. “Additions and Corrections: Stereoelectronic Control in the Electrochemical and Mercury-Promoted Reductive Acetoxylation of α,α⎹-Dibromobicycloalkanones (Journal of the American Chemical Society (1979) 101(24) (7439)).” Journal of the American Chemical Society 101, no. 24 (February 1, 1979): 7439. https://doi.org/10.1021/ja00518a610.Full Text
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Fry, A. J., W. A. Donaldson, and G. S. Ginsburg. “Reductive Acetoxylation on α, α's-Dibromocycloalkanones by Ultrasonically Dispersed Mercury.” Journal of Organic Chemistry 44, no. 3 (January 1, 1979): 349–52. https://doi.org/10.1021/jo01317a008.Full Text
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Fry, A. J., G. S. Ginsburg, and R. A. Parente. “Reduction of α,α′-dibromoketones by ultrasonically dispersed mercury in some aliphatic ketone solvents. A convenient synthesis of 4-isopropylidene-1,3-dioxolans.” Journal of the Chemical Society, Chemical Communications, no. 23 (January 1, 1978): 1040–41. https://doi.org/10.1039/C39780001040.Full Text
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Bylstra, Yasmin, Weng Khong Lim, Sylvia Kam, Koei Wan Tham, R Ryanne Wu, Jing Xian Teo, Sonia Davila, et al. “Family History Assessment Significantly Enhances Delivery of Precision Medicine in the Genomics Era,” n.d. https://doi.org/10.1101/2020.01.29.926139.Full Text
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Haga, Susanne B., Ryan Shaw, Charles Kneifel, Sarah J. Bond, and Geoffrey S. Ginsburg. “Promoting Wellness Through Mobile Health Technology in a College Student Population: Protocol Development and Pilot Study (Preprint),” n.d. https://doi.org/10.2196/preprints.16474.Full Text
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Nimmagadda, Sai N., Firas S. Midani, Heather Durand, Aspen T. Reese, Caitlin C. Murdoch, Bradley P. Nicholson, Timothy Veldman, et al. “Nasal microbiota exhibit neither reproducible nor orderly dynamics following rhinoviral infection,” n.d. https://doi.org/10.1101/2020.04.11.20061911.Full Text
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Book Sections
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Woods, C. W., and E. L. Tsalik. “Overview: Genomic and precision medicine for infectious and inflammatory disease.” In Genomic and Precision Medicine: Infectious and Inflammatory Disease, 1–7, 2019. https://doi.org/10.1016/B978-0-12-801496-7.00001-0.Full Text
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Ginsburg, G. S., and S. B. Haga. “Foundations and application of precision medicine.” In Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics: Foundations, 21–45, 2018. https://doi.org/10.1016/B978-0-12-812537-3.00002-0.Full Text
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Ward, R., and G. S. Ginsburg. “Local and Global Challenges in the Clinical Implementation of Precision Medicine.” In Genomic and Precision Medicine: Foundations, Translation, and Implementation: Third Edition, 105–17, 2017. https://doi.org/10.1016/B978-0-12-800681-8.00007-4.Full Text
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Glurich, I., S. Shukla, A. Acharya, G. S. Ginsburg, and M. H. Brilliant. “The oral microbiome and its relationship to genomics and oral disease.” In Genomics, Personalized Medicine and Oral Disease, 35–65, 2015. https://doi.org/10.1007/978-3-319-17942-1_3.Full Text
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Orlando, L. A., and A. H. cho. “Clinical Implementation of Genomic Medicine in Primary Care.” In Genomic and Personalized Medicine, edited by G. S. ginsburg and H. willard. San Diego, CA: Academic Press, 2012.
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Other Articles
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Kertai, Miklos D., Yen-Wei Li, Yi-Ju Li, Svati H. Shah, William E. Kraus, Manuel L. Fontes, Mark Stafford-Smith, et al. “G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockers.” Circ Cardiovasc Genet, October 2014. https://doi.org/10.1161/CIRCGENETICS.113.000451.Full Text Link to Item
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Potti, A., H. K. Dressman, A. Bild, R. F. Riedel, G. Chan, R. Sayer, J. Cragun, et al. “Corrigendum: Genomic signatures to guide the use of chemotherapeutics (Nature Medicine (2006) 12, (1294-1300)).” Nature Medicine, August 1, 2008. https://doi.org/10.1038/nm0808-889.Full Text
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Potti, A., H. K. Dressman, A. Bild, R. F. Riedel, G. Chan, R. Sayer, J. Cragun, et al. “Erratum: Genomic signatures to guide the use of chemotherapeutics (Nature (2006) 12, (1294-1300)).” Nature Medicine, November 1, 2007. https://doi.org/10.1038/nm1107-1388.Full Text
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Dressman, Holly K., Andrew Berchuck, Gina Chan, Jun Zhai, Andrea Bild, Robyn Sayer, Janiel Cragun, et al. “An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer.” J Clin Oncol, February 10, 2007. https://doi.org/10.1200/JCO.2006.06.3743.Full Text Link to Item
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Potti, Anil, Holly K. Dressman, Andrea Bild, Richard F. Riedel, Gina Chan, Robyn Sayer, Janiel Cragun, et al. “Genomic signatures to guide the use of chemotherapeutics.” Nat Med, November 2006. https://doi.org/10.1038/nm1491.Full Text Link to Item
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Conference Papers
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Jr, Limkakeng A. T., I. Zhbannikov, P. S. Douglas, U. Hoffman, M. Ferencik, S. Shah, W. Kraus, L. Cooper, D. Voora, and G. S. Ginsburg. “Biomarker Profiling for Obstructive Coronary Artery Disease: A PROMISE Substudy.” In Annals of Emergency Medicine, 76:S116–S116, 2020.Link to Item
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Zeitouni, Michel, Stephanie N. Giamberardino, Robert McGarrah, Neha Pagidipati, Geoffrey S. Ginsburg, Udo Hoffmann, Ann Marie Navar, Pamela Douglas, and Svati Shah. “A NOVEL INFLAMMATORY MARKER OF GLYCOSYLATED PROTEINS IS ASSOCIATED WITH CAD AND INCIDENT EVENTS AND DEMONSTRATES AGE EFFECTS IN THE PROMISE TRIAL.” In Journal of the American College of Cardiology, 75:263–263. ELSEVIER SCIENCE INC, 2020.Link to Item
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McGarrah, R. W., M. Ferencik, S. N. Giamberardino, A. Coles, U. Hoffmann, G. S. Ginsburg, W. E. Kraus, P. S. Douglas, and S. H. Shah. “Lipoprotein subclasses associated with high-risk coronary atherosclerotic plaque: insights from the PROMISE clinical trial.” In European Heart Journal, 40:51–51. OXFORD UNIV PRESS, 2019.Link to Item
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Myers, Rachel A., Thomas L. Ortel, Alexander Waldrop, Sandeep Dave, Geoffrey S. Ginsburg, and Deepak Voora. “Aspirin Responsive Platelet Genes Are Associated With Platelet Function and Reflect a Non-Cyclooxygenase Mediated Effect.” In Circulation, Vol. 138, 2018.Link to Item
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Myers, Rachel A., Thomas L. Ortel, Alexander Waldrop, Sandeep Dave, Geoffrey S. Ginsburg, and Deepak Voora. “Ticagrelor Responsive Platelet Genes Are Associated With Platelet Function and Bleeding.” In Circulation, Vol. 138, 2018.Link to Item
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Meyersohn, N. M., T. Mayrhofer, A. Ivanov, D. O. Bittner, P. V. Staziaki, B. Szilveszter, T. Hallett, et al. “Association of hepatic steatosis with adverse cardiovascular events: insights from the PROspective Multicenter Imaging Study for Evaluation of chest pain (PROMISE) trial.” In European Heart Journal, 39:1286–1286. OXFORD UNIV PRESS, 2018.Link to Item
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Orlando, Lori A., R. R. Wu, Adam Buchanan, Rachel A. Myers, and Geoffrey S. Ginsburg. “THE INTERSECTION OF POPULATION HEALTH AND PRECISION MEDICINE: EMPLOYING TECHNOLOGY TO OPTIMIZE RISK ASSESSMENT IN PRIMARY CARE.” In Journal of General Internal Medicine, 33:S362–S362. SPRINGER, 2018.Link to Item
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Tillekeratne, L., Sunil Suchindran, Emily Ko, Elizabeth Petzold, Champica Bodinayake, Ajith Nagahawatte, Vasantha Devasiri, et al. “A GENE EXPRESSION SIGNATURE ACCURATELY IDENTIFIES VIRAL ACUTE RESPIRATORY INFECTIONS IN A SRI LANKAN POPULATION.” In American Journal of Tropical Medicine and Hygiene, 99:641–42. AMER SOC TROP MED & HYGIENE, 2018.Link to Item
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Januzzi, James L., Sunil Suchindran, Adrian Coles, Maros Ferencik, Manesh R. Patel, Udo Hoffmann, Geoffrey S. Ginsburg, and Pamela S. Douglas. “High Sensitivity Troponin I Measurement in Symptomatic Outpatients With Suspected Coronary Artery Disease: Results From the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) Study.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.Link to Item
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McGarrah, Robert W., Ann M. Navar, Stephanie Giamberardino, Adrian Coles, Lydia C. Kwee, Udo Hoffmann, Geoffrey S. Ginsburg, William E. Kraus, Pamela S. Douglas, and Svati H. Shah. “NMR Lipoprotein Profiling Identifies HDL Subclasses Associated With Obstructive CAD: Insights From the PROMISE Clinical Trial.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.Link to Item
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Ngo, H. T., H. N. Wang, T. Burke, C. Woods, G. S. Ginsburg, and T. Vo-Dinh. “Multiplex DNA biosensor for viral infection diagnosis using SERS molecular sentinel-on-chip.” In Ifmbe Proceedings, 46:15–20, 2015. https://doi.org/10.1007/978-3-319-11776-8_4.Full Text
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Li, Josephine H., Sunil Suchindran, Svati H. Shah, William E. Kraus, Geoffrey S. Ginsburg, and Deepak Voora. “Effect of SLCO1B1*5 on Low-Density Lipoprotein Cholesterol Levels and Long-Term Clinical Events in Patients During Statin Therapy Following Cardiac Catheterization.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Cho, Alex, Allison Vorderstrasse, Sunil Suchindran, Joseph Lucas, William Michael Scott, Marylou Bembe, Dana Baker, et al. “T2D Genetic Risk Counseling & Testing in Primary Care.” In Diabetes, 62:A196–A196. AMER DIABETES ASSOC, 2013.Link to Item
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Wu, Rebekah R., Tiffany Himmel, Adam Buchanan, Karen Powell, Elizabeth Hauser, Astrid B. Agbaje, Geoffrey S. Ginsburg, Vincent Henrich, and Lori A. Orlando. “IMPACT OF A FAMILY HISTORY COLLECTION TOOL, METREE (c), IN IDENTIFYING INDIVIDUALS AT HIGH-RISK FOR CANCER AND THROMBOSIS.” In Journal of General Internal Medicine, 28:S101–S101. SPRINGER, 2013.Link to Item
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Wu, Rebekah R., Tiffany Himmel, Karen Powell, Elizabeth Hauser, Astrid B. Agbaje, Vincent Henrich, Geoffrey S. Ginsburg, and Lori A. Orlando. “USABILITY OF A FAMILY HEALTH HISTORY AND CLINICAL DECISION SUPPORT TOOL FOR PATIENTS AND PRIMARY CARE PROVIDERS.” In Journal of General Internal Medicine, 28:S233–S233. SPRINGER, 2013.Link to Item
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Kraft, B., C. A. Piantadosi, H. B. Suliman, G. S. Ginsburg, R. R. Bartz, A. Zaas, M. Betancourt, and K. E. Welty-Wolf. “Pneumococcal Pneumonia And Sepsis In Baboons Mirrors The Human Disease.” In American Journal of Respiratory and Critical Care Medicine, Vol. 187. AMER THORACIC SOC, 2013.Link to Item
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Tingley, Whittemore G., James A. Wingrove, Amy J. Sehnert, Michael Elashoff, Susan E. Daniels, Steven Rosenberg, Lutz Buellesfeld, et al. “Gene Expression in Peripheral Blood Reflects the Presence and Extent of Coronary Artery Stenosis.” In American Journal of Cardiology, 102:55I-55I. EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, 2008.Link to Item
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Shah, Svati H., James Bain, Michael J. Muehlbauer, Robert D. Stevens, Brett R. Wenner, Lauren C. Naliboff, Carol Haynes, et al. “Peripheral blood metabolic signatures are markers of coronary artery disease and myocardial infarction.” In Circulation, Vol. 117. LIPPINCOTT WILLIAMS & WILKINS, 2008.Link to Item
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Shah, Svati H., Christopher B. Newgard, James Bain, Robert Stevens, Brett Wenner, Michael Muehlbauer, Elaine Dowdy, et al. “High heritabilities of serum metabolites and differential metabolomic profiles in families burdened with early onset coronary artery disease.” In Circulation, 114:677–677. LIPPINCOTT WILLIAMS & WILKINS, 2006.Link to Item
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Ginsburg, Geoffrey S., Julie Lekstrom-Himes, and William Trepicchio. “Optimizing biomarker development for clinical studies at the lead optimization stage of drug development.” In Optimizing the Drug Like Properties of Leads in Drug Discovery, edited by R. T. Borchardt, E. H. Kerns, M. J. Hageman, D. R. Thakker, and J. L. Stevens, 4:411-+. SPRINGER, 2006.Link to Item
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- Teaching & Mentoring
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Recent Courses
- Scholarly, Clinical, & Service Activities
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Outreach & Engaged Scholarship
- Bass Connections Team Leader. Smart Toilet: A Disruptive Technology to Improve Health and Wellness. 2020 - 2021 2020 - 2021
- Bass Connections Team Leader. Smart Toilet: A Disruptive Technology to Improve Health and Wellness. 2019 - 2020 2019 - 2020
- Bass Connections Faculty Team Leader. Enabling Precision Health and Medicine. 2018 - 2019 2018 - 2019
- Bass Connections Faculty Team Member . Blue Devil Resistome Project. August 2017 - May 2018 2017 - 2018
- Bass Connections Faculty Team Member. Enabling Precision Health and Medicine. August 2017 - May 2018 2017 - 2018
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