Geoffrey Steven Ginsburg

Geoffrey Steven Ginsburg
Adjunct Professor in the Department of Medicine

Dr. Geoffrey S. Ginsburg's research interests are in the development of novel paradigms for developing and translating genomic information into medical practice and the integration of personalized medicine into health care.

Current Appointments & Affiliations

Adjunct Professor in the Department of Medicine, Medicine, Cardiology, Medicine 2022
Director of Duke Center for Applied Genomics and Precision Medicine, Duke Center for Applied Genomics and Precision Medicine, Medicine 2014
Professor in Pathology, Pathology, Clinical Science Departments 2006
Professor in the School of Nursing, School of Nursing, Duke University 2016
Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2021
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2004

Contact Information

101 Science Dr, Rm 2111, CIEMAS Bldg, Durham, NC 27708
Duke Box 3382, Durham, NC 27710
(919) 668-6210
Google Scholar

Background
Education, Training, & Certifications
- Research Fellow in Cardiology, Medicine, Children's Hospital Boston 1987 - 1990
- Fellow in Cardiology, Medicine, Beth Israel Deaconess Medical Center 1987 - 1990
- Medical Resident, Medicine, Beth Israel Deaconess Medical Center 1984 - 1987
- M.D., Boston University 1984
- Ph.D., Boston University 1984
Previous Appointments & Affiliations
- Professor of Medicine, Medicine, Cardiology, Medicine 2005 - 2021
- Director of MEDx (Medicine and Engineering at Duke), Pratt School of Engineering, Duke University 2015 - 2018
- Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2014 - 2017
- Director of the IGSP Center for Genomic Medicine, Institutes and Centers, School of Medicine 2010 - 2014
- Instructor, Temporary in the Department of Medicine, Medicine, Cardiology, Medicine 2004 - 2005
Recognition
In the News
- MAR 16, 2021 Precision Medicine
  
  A Combination of Family History and Genomic Screening Provides Best Method of Assessing Cancer Risk
- AUG 25, 2020 Duke Magnify
  
  Early Detection of COVID-19: How Your Smartwatch Could Help
- JAN 9, 2020
  
  A Crystal Ball for the Decade Ahead
- AUG 21, 2019 Pratt School of Engineering
  
  Hungry for Innovation: How a MEDx Dinner Led to a Newly Patented Medical Tool
- JAN 10, 2019 Pratt School of Engineering
  
  Fecal Matters: Learning About Health Through Waste
- NOV 1, 2018 Duke Health News
  
  Medical Researchers Receive $20 Million in Grants for Genomic Medicine and Breast Cancer Research
- FEB 22, 2017 Duke Health News
  
  Proteins in Your Runny Nose Could Reveal a Viral Infection
- DEC 15, 2015
  
  Time to Focus on Your Family Health History
- OCT 21, 2015 U.S. News & World Report
  
  Dr. Geoffrey Ginsburg: The evolution of precision medicine
- OCT 20, 2015 Nature
  
  Diagnostic developers target antibiotic resistance
- OCT 11, 2015
  
  Bacterial or Viral? Diagnostic Tool May Help Doctors Track Infection Source
- AUG 10, 2015
  
  Ginsburg Named Director of School of Medicine-Pratt School Partnership
- JUN 20, 2014 Newsweek
  
  A fruit billionaire tries to rewrite the textbook on medicine
- MAR 24, 2014
  
  Duke Announces Reorganization of Genome Sciences
- SEP 19, 2013 CBS News, AP
  
  Blood test can determine whether illness is caused by virus or bacteria
- SEP 18, 2013
  
  Genomic Test Accurately Sorts Viral vs. Bacterial Infections
- JUL 7, 2013
  
  Is Aspirin Therapy for You?
Expertise
Subject Headings
Global Scholarship
- Research
Research
Selected Grants
- NHGRI Research Training and Career Development Annual Meeting awarded by National Institutes of Health 2021 - 2026
- Duke University Program in Environmental Health awarded by National Institutes of Health 2013 - 2024
- Rapid, point-of-care, host gene expression test for presymptomatic viral infection and to distinguish bacterial from viral illness awarded by Department of Defense 2021 - 2023
- Transplant Infectious Diseases Interdisciplinary Research Training Grant (TIDIRTG) awarded by National Institutes of Health 2018 - 2023
- Building and Deploying a Genomic-Medicine Risk Assessment Model for Diverse Primary Care Populations. awarded by National Institutes of Health 2018 - 2023
- The IGNITE II CC: Engagement, Coordination, Demonstration, and Dissemination awarded by National Institutes of Health 2018 - 2023
- Abbott Diagnostics Collaborative Sponsored Research Agreement awarded by Abbott Laboratories 2016 - 2022
- Preparing Genetic Counselors for Genomic Medicine Research awarded by National Institutes of Health 2017 - 2022
- Medical Scientist Training Program awarded by National Institutes of Health 1997 - 2022
- The Role of Junctophilin Type 2 in Cardiac Node Automaticity awarded by National Institutes of Health 2018 - 2022
- Postdoctoral Training in Genomic Medicine Research awarded by National Institutes of Health 2017 - 2022
- Multidisciplinary Heart and Vascular Diseases awarded by National Institutes of Health 1975 - 2022
- Mapping Epigenetic Memory of Exposure New To Observe (MEMENTO) awarded by Defense Advanced Research Projects Agency 2019 - 2022
- Resilience Prediction to RSV Infection awarded by Sanofi US 2018 - 2021
- One-Carbon Metabolism Genetics Data Analyses awarded by KBRwyle 2020 - 2021
- Predicting prebiotic effects on human microbiota, behavior, and cognition. awarded by Office of Naval Research 2018 - 2021
- Interdisciplinary Training Program in Lung Disease awarded by National Institutes of Health 2009 - 2021
- Transfusion Medicine and Hematology awarded by National Institutes of Health 1975 - 2021
- Human-Based Sensor System for Presymptomatic Biological Exposure Detection awarded by Research Triangle Institute International 2019 - 2021
- Study of Prognostic Biomarkers of Severe Systemic Bacterial Infection awarded by Genetech 2016 - 2020
- PREdicting contagion using Systems And GEnomic analysis (PRESAGE) awarded by Defense Advanced Research Projects Agency 2017 - 2020
- Novel host-based diagnostics of febrile illness in the warfighter awarded by Department of Defense 2016 - 2020
- MicroRNA Profiling to Characterize and Predict Posttraumatic Epilepsy following Traumatic Brain Injury awarded by Department of Defense 2018 - 2020
- Implementation, Adoption, and Utility of Family History in Diverse Care Settings awarded by National Institutes of Health 2013 - 2019
- Duke University Program in Environmental Health awarded by National Institute of Environmental Health Sciences 2013 - 2019
- Duke-UNC Clinical Hematology and Transfusion Research Career Development Program awarded by National Institutes of Health 2006 - 2019
- Development of Prognostic Platelet RNA Biomarkers To Tailor Antiplatelet Therapy awarded by National Institutes of Health 2013 - 2019
- Development and Application of Mathematical Methods for Tracking Biochronicity and Baseline Variation awarded by Defense Advanced Research Projects Agency 2016 - 2019
- Impact of Personal Genomic Testing on Primary Care Physician Knowledge and Attitudes awarded by 23andMe, Inc 2017 - 2018
- Novel Dialysis-Like Therapeutics in Sepsis-induced Shock and Organ Failure awarded by Defense Advanced Research Projects Agency 2015 - 2018
- Genetics of Normal Human Variation: Implications for Disease awarded by National Institutes of Health 2013 - 2017
- Genetic Risk Testing & Health Coaching for T2D and CHD awarded by Air Force Office of Scientific Research 2013 - 2017
- Feasibility for Predicting Warfighter Health Using Transcriptional Markers on the MAP Platform awarded by Ibis Biosciences, Inc. 2016
- Baseline Bio-molecular Models to Predict Infectious Disease Susceptibility awarded by Defense Advanced Research Projects Agency 2015 - 2016
- The Duke Multidisciplinary Training Program in Pediatric Lung Disease awarded by National Institutes of Health 2010 - 2016
- Plasmonics-Active SERS Nanoplatforms for In Vivo Diagnostics awarded by Defense Advanced Research Projects Agency 2012 - 2016
- Validation of the host transcription diagnostic for prediction of incipient respiratory viral infection awarded by Defense Advanced Research Projects Agency 2014 - 2016
- Pharmacogenetic Testing: Challenges of Clinical Integration awarded by National Institutes of Health 2007 - 2015
- Multidisciplinary Neonatal Training Grant awarded by National Institutes of Health 2010 - 2015
- Implications of Health and Genetic Literacy for Genomic Medicine awarded by National Institutes of Health 2010 - 2012
- CTSA UL awarded by National Institutes of Health 2006 - 2012
- Phase I Clinical Trial Describing the Pharmacogenomics of Aspirin awarded by National Institutes of Health 2009 - 2012
- Programs in Clinical Effectiveness of Cancer Pharmacogenomics awarded by National Institutes of Health 2009 - 2012
- Enabling Personalized Medicine through Clinical Decision Support awarded by National Institutes of Health 2008 - 2011
- Duke Clinical and Translational Science Institute awarded by National Institutes of Health 2006 - 2011
External Relationships
- AbbVie, Inc.
- Coprata, LLC
- Elsevier
- Fabric Genomics
- Global Genomic Medicine Collaborative
- Konica-Minolta
- MeTree&You
- Peer Medical
- Predigen, Inc.
- origin commercial advisor
Publications & Artistic Works
Selected Publications
- Books
  - Ginsburg, G. S., E. L. Tsalik, H. F. Willard, and C. W. Woods. Genomic and precision medicine: Infectious and inflammatory disease, 2019. https://doi.org/10.1016/C2015-0-06902-7.
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  - Ginsburg, G. S., and H. F. Willard. Genomic and precision medicine: Cardiovascular disease: Third edition, 2017.
  - David, S. P., H. F. Willard, and G. S. Ginsburg. Preface, 2017. https://doi.org/10.1016/B978-0-12-800685-6.00021-7.
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  - Ginsburg, G. S., and H. F. Willard. Genomic and Precision Medicine: Foundations, Translation, and Implementation: Third Edition, 2016.
  - Ginsburg, G. G., and H. H. Willard. Essentials of Genomic and Personalized Medicine, 2010.
  - Ginsburg, G. S., and H. F. Willard. Genomic and Personalized Medicine, Two-Vol Set, 2009. https://doi.org/10.1016/B978-0-12-369420-1.X0001-7.
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- Academic Articles
  - Cho, Peter Jaeho, Jaehan Jeremy Yi, Ethan Ho, Yen Hai Dinh, Mobashir Hasan Shandhi, Aneesh Patil, Leatrice Martin, et al. “Demographic Imbalances Resulting from Bring-Your-Own-Device Study Design.” Jmir Mhealth and Uhealth, December 15, 2021. https://doi.org/10.2196/29510.
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  - Manolio, Teri A., Carol J. Bult, Rex L. Chisholm, Patricia A. Deverka, Geoffrey S. Ginsburg, Madison Goldrich, Gail P. Jarvik, et al. “Genomic medicine year in review: 2021.” Am J Hum Genet 108, no. 12 (December 2, 2021): 2210–14. https://doi.org/10.1016/j.ajhg.2021.11.006.
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  - Jaffe, Ian S., Anja K. Jaehne, Eugenia Quackenbush, Emily R. Ko, Emanuel P. Rivers, Micah T. McClain, Geoffrey S. Ginsburg, Christopher W. Woods, and Ephraim L. Tsalik. “Comparing the Diagnostic Accuracy of Clinician Judgment to a Novel Host Response Diagnostic for Acute Respiratory Illness.” Open Forum Infectious Diseases 8, no. 12 (December 2021): ofab564. https://doi.org/10.1093/ofid/ofab564.
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  - Sharma, Abhinav, James L. Januzzi, Sunil Suchindran, Adrian Coles, Udo Hoffmann, Maros Ferencik, Manesh R. Patel, Geoffrey S. Ginsburg, and Pamela S. Douglas. “Utility of High-Sensitivity Troponin Among Stable Patients With Chest Pain Undergoing Stress Imaging (from PROMISE).” Am J Cardiol 158 (November 1, 2021): 148–49. https://doi.org/10.1016/j.amjcard.2021.07.032.
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  - Myers, Rachel A., Thomas L. Ortel, Alexander Waldrop, Sandeep Dave, Geoffrey S. Ginsburg, and Deepak Voora. “Aspirin effects on platelet gene expression are associated with a paradoxical, increase in platelet function.” Br J Clin Pharmacol, October 27, 2021. https://doi.org/10.1111/bcp.15127.
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  - Yoon, Sungwon, Hendra Goh, Si Ming Fung, Shihui Tang, David Matchar, Geoffrey S. Ginsburg, Lori A. Orlando, Joanne Ngeow, and Rebekah Ryanne Wu. “Experience and Perceptions of a Family Health History Risk Assessment Tool among Multi-Ethnic Asian Breast Cancer Patients.” J Pers Med 11, no. 10 (October 19, 2021). https://doi.org/10.3390/jpm11101046.
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  - Ginsburg, Geoffrey, Michelle Penny, W Gregory Feero, Mona Miller, Siobhan Addie, and Sarah H. Beachy. “The National Academies' Roundtable on Genomics and Precision Health: Where we have been and where we are heading.” Am J Hum Genet 108, no. 10 (October 7, 2021): 1817–22. https://doi.org/10.1016/j.ajhg.2021.08.015.
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  - Levy, Kenneth D., Kathryn Blake, Colette Fletcher-Hoppe, James Franciosi, Daisuke Goto, James K. Hicks, Ann M. Holmes, et al. “Correction: Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network.” Genet Med 23, no. 10 (October 2021): 2020. https://doi.org/10.1038/s41436-020-01054-0.
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  - Tsalik, Ephraim L., Ricardo Henao, Jesse L. Montgomery, Jeff W. Nawrocki, Mert Aydin, Emily C. Lydon, Emily R. Ko, et al. “Discriminating Bacterial and Viral Infection Using a Rapid Host Gene Expression Test.” Crit Care Med 49, no. 10 (October 1, 2021): 1651–63. https://doi.org/10.1097/CCM.0000000000005085.
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  - Grzesiak, Emilia, Brinnae Bent, Micah T. McClain, Christopher W. Woods, Ephraim L. Tsalik, Bradly P. Nicholson, Timothy Veldman, et al. “Assessment of the Feasibility of Using Noninvasive Wearable Biometric Monitoring Sensors to Detect Influenza and the Common Cold Before Symptom Onset.” Jama Netw Open 4, no. 9 (September 1, 2021): e2128534. https://doi.org/10.1001/jamanetworkopen.2021.28534.
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  - Mahle, Rachael E., Sunil Suchindran, Ricardo Henao, Julie M. Steinbrink, Thomas W. Burke, Micah T. McClain, Geoffrey S. Ginsburg, Christopher W. Woods, and Ephraim L. Tsalik. “Validation of a Host Gene Expression Test for Bacterial/Viral Discrimination in Immunocompromised Hosts.” Clin Infect Dis 73, no. 4 (August 16, 2021): 605–13. https://doi.org/10.1093/cid/ciab043.
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  - She, Xichen, Yaya Zhai, Ricardo Henao, Christopher W. Woods, Christopher Chiu, Geoffrey S. Ginsburg, Peter X. K. Song, and Alfred O. Hero. “Adaptive Multi-Channel Event Segmentation and Feature Extraction for Monitoring Health Outcomes.” Ieee Trans Biomed Eng 68, no. 8 (August 2021): 2377–88. https://doi.org/10.1109/TBME.2020.3038652.
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  - Chen, Lingye, Bryan D. Kraft, Victor L. Roggli, Zachary R. Healy, Christopher W. Woods, Ephraim L. Tsalik, Geoffrey S. Ginsburg, et al. “Heparin-based blood purification attenuates organ injury in baboons with Streptococcus pneumoniae pneumonia.” Am J Physiol Lung Cell Mol Physiol 321, no. 2 (August 1, 2021): L321–35. https://doi.org/10.1152/ajplung.00337.2020.
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  - Sperber, Nina R., Olivia M. Dong, Megan C. Roberts, Paul Dexter, Amanda R. Elsey, Geoffrey S. Ginsburg, Carol R. Horowitz, et al. “Strategies to Integrate Genomic Medicine into Clinical Care: Evidence from the IGNITE Network.” J Pers Med 11, no. 7 (July 8, 2021). https://doi.org/10.3390/jpm11070647.
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  - Bylstra, Yasmin, Weng Khong Lim, Sylvia Kam, Koei Wan Tham, R Ryanne Wu, Jing Xian Teo, Sonia Davila, et al. “Correction to: Family history assessment significantly enhances delivery of precision medicine in the genomics era.” Genome Med 13, no. 1 (July 5, 2021): 109. https://doi.org/10.1186/s13073-021-00916-9.
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  - Steinbrink, Julie M., Rachel A. Myers, Kaiyuan Hua, Melissa D. Johnson, Jessica L. Seidelman, Ephraim L. Tsalik, Ricardo Henao, et al. “The host transcriptional response to Candidemia is dominated by neutrophil activation and heme biosynthesis and supports novel diagnostic approaches.” Genome Medicine 13, no. 1 (July 5, 2021): 108. https://doi.org/10.1186/s13073-021-00924-9.
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  - Ginsburg, Geoffrey S., Larisa H. Cavallari, Hrishikesh Chakraborty, Rhonda M. Cooper-DeHoff, Paul R. Dexter, Michael T. Eadon, Bart S. Ferket, et al. “Establishing the value of genomics in medicine: the IGNITE Pragmatic Trials Network.” Genet Med 23, no. 7 (July 2021): 1185–91. https://doi.org/10.1038/s41436-021-01118-9.
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  - Meyersohn, Nandini M., Thomas Mayrhofer, Kathleen E. Corey, Daniel O. Bittner, Pedro V. Staziaki, Balint Szilveszter, Travis Hallett, et al. “Association of Hepatic Steatosis With Major Adverse Cardiovascular Events, Independent of Coronary Artery Disease.” Clin Gastroenterol Hepatol 19, no. 7 (July 2021): 1480-1488.e14. https://doi.org/10.1016/j.cgh.2020.07.030.
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  - Wang, Liuyang, Thomas J. Balmat, Alejandro L. Antonia, Florica J. Constantine, Ricardo Henao, Thomas W. Burke, Andy Ingham, et al. “An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility.” Genome Med 13, no. 1 (May 17, 2021): 83. https://doi.org/10.1186/s13073-021-00904-z.
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  - Kammerlander, Andreas A., Thomas Mayrhofer, Maros Ferencik, Neha J. Pagidipati, Julia Karady, Geoffrey S. Ginsburg, Michael T. Lu, et al. “Association of Metabolic Phenotypes With Coronary Artery Disease and Cardiovascular Events in Patients With Stable Chest Pain.” Diabetes Care 44, no. 4 (April 2021): 1038–45. https://doi.org/10.2337/dc20-1760.
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  - Fung, Si Ming, R Ryanne Wu, Rachel A. Myers, Jasper Goh, Geoffrey S. Ginsburg, David Matchar, Lori A. Orlando, and Joanne Ngeow. “Clinical implementation of an oncology-specific family health history risk assessment tool.” Hered Cancer Clin Pract 19, no. 1 (March 20, 2021): 20. https://doi.org/10.1186/s13053-021-00177-y.
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  - McClain, Micah T., Florica J. Constantine, Bradly P. Nicholson, Marshall Nichols, Thomas W. Burke, Ricardo Henao, Daphne C. Jones, et al. “A blood-based host gene expression assay for early detection of respiratory viral infection: an index-cluster prospective cohort study.” Lancet Infect Dis 21, no. 3 (March 2021): 396–404. https://doi.org/10.1016/S1473-3099(20)30486-2.
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  - McClain, Micah T., Florica J. Constantine, Ricardo Henao, Yiling Liu, Ephraim L. Tsalik, Thomas W. Burke, Julie M. Steinbrink, et al. “Dysregulated transcriptional responses to SARS-CoV-2 in the periphery.” Nat Commun 12, no. 1 (February 17, 2021): 1079. https://doi.org/10.1038/s41467-021-21289-y.
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  - Infeld, Margaret, Kevin A. Friede, Tan Ru San, Holly J. Knickerbocker, Geoffrey S. Ginsburg, Thomas L. Ortel, and Deepak Voora. “Platelet reactivity in response to aspirin and ticagrelor in African-Americans and European-Americans.” J Thromb Thrombolysis 51, no. 2 (February 2021): 249–59. https://doi.org/10.1007/s11239-020-02327-w.
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  - Perakslis, Eric, and Geoffrey S. Ginsburg. “Digital Health-The Need to Assess Benefits, Risks, and Value.” Jama 325, no. 2 (January 12, 2021): 127–28. https://doi.org/10.1001/jama.2020.22919.
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  - Bylstra, Yasmin, Weng Khong Lim, Sylvia Kam, Koei Wan Tham, R Ryanne Wu, Jing Xian Teo, Sonia Davila, et al. “Family history assessment significantly enhances delivery of precision medicine in the genomics era.” Genome Med 13, no. 1 (January 7, 2021): 3. https://doi.org/10.1186/s13073-020-00819-1.
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  - McCarthy, Jeanette, George Patrinos, and Geoffrey Ginsburg. “Welcome to the 18th volume of Personalized Medicine.” Per Med 18, no. 1 (January 2021): 1–3. https://doi.org/10.2217/pme-2020-0176.
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  - Ross, Melissa, Ricardo Henao, Thomas W. Burke, Emily R. Ko, Micah T. McClain, Geoffrey S. Ginsburg, Christopher W. Woods, and Ephraim L. Tsalik. “A comparison of host response strategies to distinguish bacterial and viral infection.” Plos One 16, no. 12 (2021): e0261385. https://doi.org/10.1371/journal.pone.0261385.
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  - She, Xichen, Yaya Zhai, Ricardo Henao, Christopher W. Woods, Christopher Chiu, Geoffrey S. Ginsburg, Peter X. K. Song, and Alfred O Hero III. “Adaptive Multi-Channel Event Segmentation and Feature Extraction for Monitoring Health Outcomes.” Ieee Trans. Biomed. Eng. 68 (2021): 2377–88. https://doi.org/10.1109/TBME.2020.3038652.
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  - Tsalik, Ephraim L., Cassandra Fiorino, Ammara Aqeel, Yiling Liu, Ricardo Henao, Emily R. Ko, Thomas W. Burke, et al. “The Host Response to Viral Infections Reveals Common and Virus-Specific Signatures in the Peripheral Blood.” Front Immunol 12 (2021): 741837. https://doi.org/10.3389/fimmu.2021.741837.
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  - Wang, Liuyang, Thomas J. Balmat, Alejandro L. Antonia, Florica J. Constantine, Ricardo Henao, Thomas W. Burke, Andy Ingham, et al. “An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility.” Medrxiv, December 22, 2020. https://doi.org/10.1101/2020.12.20.20248572.
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  - Giroux, Nicholas S., Shengli Ding, Micah T. McClain, Thomas W. Burke, Elizabeth Petzold, Hong A. Chung, Grecia R. Palomino, et al. “Chromatin remodeling in peripheral blood cells reflects COVID-19 symptom severity.” Biorxiv, December 9, 2020. https://doi.org/10.1101/2020.12.04.412155.
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  - Manolio, Teri A., Carol J. Bult, Rex L. Chisholm, Patricia A. Deverka, Geoffrey S. Ginsburg, Madison Goldrich, Gail P. Jarvik, et al. “Genomic Medicine Year in Review: 2020.” Am J Hum Genet 107, no. 6 (December 3, 2020): 1007–10. https://doi.org/10.1016/j.ajhg.2020.11.005.
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  - Orlando, Lori A., R Ryanne Wu, Rachel A. Myers, Joan Neuner, Catherine McCarty, Irina V. Haller, Melissa Harry, et al. “At the intersection of precision medicine and population health: an implementation-effectiveness study of family health history based systematic risk assessment in primary care.” Bmc Health Serv Res 20, no. 1 (November 7, 2020): 1015. https://doi.org/10.1186/s12913-020-05868-1.
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  - Manolio, T. A., P. Goodhand, and G. Ginsburg. “The International Hundred Thousand Plus Cohort Consortium: integrating large-scale cohorts to address global scientific challenges.” The Lancet Digital Health 2, no. 11 (November 1, 2020): e567–68. https://doi.org/10.1016/S2589-7500(20)30242-9.
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  - Levy, Kenneth D., Kathryn Blake, Colette Fletcher-Hoppe, James Franciosi, Diasuke Goto, James K. Hicks, Ann M. Holmes, et al. “Correction: Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network.” Genet Med 22, no. 10 (October 2020): 1730. https://doi.org/10.1038/s41436-020-0911-5.
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  - Belcher, Andrea, Geoffrey S. Ginsburg, and Robyn Ward. “Global approaches to genomic medicine implementation.” Sci Transl Med 12, no. 563 (September 30, 2020). https://doi.org/10.1126/scitranslmed.aax0911.
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  - McClain, Micah T., Florica J. Constantine, Ricardo Henao, Yiling Liu, Ephraim L. Tsalik, Thomas W. Burke, Julie M. Steinbrink, et al. “Dysregulated transcriptional responses to SARS-CoV-2 in the periphery support novel diagnostic approaches.” Medrxiv, July 26, 2020. https://doi.org/10.1101/2020.07.20.20155507.
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  - Friede, Kevin A., Margaret M. Infeld, Ru San Tan, Holly J. Knickerbocker, Rachel A. Myers, Laura G. Dubois, J Will Thompson, et al. “Influence of Sex on Platelet Reactivity in Response to Aspirin.” J Am Heart Assoc 9, no. 14 (July 21, 2020): e014726. https://doi.org/10.1161/JAHA.119.014726.
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  - Wu, R Ryanne, Rehena Sultana, Yasmin Bylstra, Saumya Jamuar, Sonia Davila, Weng Khong Lim, Geoffrey S. Ginsburg, et al. “Evaluation of family health history collection methods impact on data and risk assessment outcomes.” Prev Med Rep 18 (June 2020): 101072. https://doi.org/10.1016/j.pmedr.2020.101072.
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  - Tillekeratne, L Gayani, Sunil Suchindran, Emily R. Ko, Elizabeth A. Petzold, Champica K. Bodinayake, Ajith Nagahawatte, Vasantha Devasiri, et al. “Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population.” Open Forum Infect Dis 7, no. 6 (June 2020): ofaa194. https://doi.org/10.1093/ofid/ofaa194.
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  - Haga, Susanne B., Ryan Shaw, Charles Kneifel, Sarah J. Bond, and Geoffrey S. Ginsburg. “Promoting Wellness Through Mobile Health Technology in a College Student Population: Protocol Development and Pilot Study.” Jmir Res Protoc 9, no. 4 (April 3, 2020): e16474. https://doi.org/10.2196/16474.
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  - Arges, Kristine, Themistocles Assimes, Vikram Bajaj, Suresh Balu, Mustafa R. Bashir, Laura Beskow, Rosalia Blanco, et al. “The Project Baseline Health Study: a step towards a broader mission to map human health.” Npj Digit Med 3 (2020): 84. https://doi.org/10.1038/s41746-020-0290-y.
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  - Manolio, Teri A., Carol J. Bult, Rex L. Chisholm, Patricia A. Deverka, Geoffrey S. Ginsburg, Gail P. Jarvik, Howard L. McLeod, et al. “Genomic Medicine Year in Review: 2019.” Am J Hum Genet 105, no. 6 (December 5, 2019): 1072–75. https://doi.org/10.1016/j.ajhg.2019.11.006.
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  - Ginsburg, Geoffrey S., Ebony Madden, and Philip E. Empey. “Affiliate network members as force amplifiers of genomic medicine research.” Per Med 16, no. 6 (November 2019): 431–33. https://doi.org/10.2217/pme-2019-0077.
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  - Tsalik, Ephraim L., Ayeaye Khine, Abdossamad Talebpour, Alaleh Samiei, Vilcy Parmar, Thomas W. Burke, Micah T. Mcclain, et al. “Rapid, Sample-to-Answer Host Gene Expression Test to Diagnose Viral Infection.” Open Forum Infectious Diseases 6, no. 11 (November 2019): ofz466. https://doi.org/10.1093/ofid/ofz466.
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  - Lydon, Emily C., Ricardo Henao, Thomas W. Burke, Mert Aydin, Bradly P. Nicholson, Seth W. Glickman, Vance G. Fowler, et al. “Validation of a host response test to distinguish bacterial and viral respiratory infection.” Ebiomedicine 48 (October 2019): 453–61. https://doi.org/10.1016/j.ebiom.2019.09.040.
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  - Ginsburg, Geoffrey S., R Ryanne Wu, and Lori A. Orlando. “Family health history: underused for actionable risk assessment.” Lancet 394, no. 10198 (August 17, 2019): 596–603. https://doi.org/10.1016/S0140-6736(19)31275-9.
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  - Manolio, Teri A., Robb Rowley, Marc S. Williams, Dan Roden, Geoffrey S. Ginsburg, Carol Bult, Rex L. Chisholm, et al. “Opportunities, resources, and techniques for implementing genomics in clinical care.” Lancet 394, no. 10197 (August 10, 2019): 511–20. https://doi.org/10.1016/S0140-6736(19)31140-7.
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  - Sutton, Lynn, Lisa G. Berdan, Jean Bolte, Robert M. Califf, Geoffrey S. Ginsburg, Jennifer S. Li, Jonathan McCall, et al. “Facilitating translational team science: The project leader model.” J Clin Transl Sci 3, no. 4 (August 2019): 140–46. https://doi.org/10.1017/cts.2019.398.
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  - Ginsburg, Geoffrey S., Carol R. Horowitz, and Lori A. Orlando. “What will it take to implement genomics in practice? Lessons from the IGNITE Network.” Per Med 16, no. 4 (July 2019): 259–61. https://doi.org/10.2217/pme-2019-0021.
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  - Levy, Kenneth D., Kathryn Blake, Colette Fletcher-Hoppe, James Franciosi, Diasuke Goto, James K. Hicks, Ann M. Holmes, et al. “Correction: Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network.” Genet Med 21, no. 7 (July 2019): 1670. https://doi.org/10.1038/s41436-018-0280-5.
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  - Zebrowski, Alexis M., Darcy E. Ellis, Frances K. Barg, Nina R. Sperber, Barbara A. Bernhardt, Joshua C. Denny, Paul R. Dexter, et al. “Qualitative study of system-level factors related to genomic implementation.” Genet Med 21, no. 7 (July 2019): 1534–40. https://doi.org/10.1038/s41436-018-0378-9.
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  - Januzzi, James L., Sunil Suchindran, Adrian Coles, Maros Ferencik, Manesh R. Patel, Udo Hoffmann, Geoffrey S. Ginsburg, Pamela S. Douglas, and Pamela S. PROMISE Investigators. “High-Sensitivity Troponin I and Coronary Computed Tomography in Symptomatic Outpatients With Suspected CAD: Insights From the PROMISE Trial.” Jacc Cardiovasc Imaging 12, no. 6 (June 2019): 1047–55. https://doi.org/10.1016/j.jcmg.2018.01.021.
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  - Haga, Susanne B., Esther Kim, Rachel A. Myers, and Geoffrey S. Ginsburg. “Primary Care Physicians' Knowledge, Attitudes, and Experience with Personal Genetic Testing.” J Pers Med 9, no. 2 (May 24, 2019). https://doi.org/10.3390/jpm9020029.
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  - Januzzi, James L., Geoffrey S. Ginsburg, and Pamela S. Douglas. “Reply: hs-cTnI in Stable Chest Pain.” J Am Coll Cardiol 73, no. 16 (April 30, 2019): 2121–22. https://doi.org/10.1016/j.jacc.2019.02.050.
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  - Ginsburg, Geoffrey S. “A Global Collaborative to Advance Genomic Medicine.” Am J Hum Genet 104, no. 3 (March 7, 2019): 407–9. https://doi.org/10.1016/j.ajhg.2019.02.010.
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  - Levy, Kenneth D., Kathryn Blake, Colette Fletcher-Hoppe, James Franciosi, Daisuke Goto, James K. Hicks, Ann M. Holmes, et al. “Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network.” Genet Med 21, no. 3 (March 2019): 743–47. https://doi.org/10.1038/s41436-018-0080-y.
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  - Wu, R Ryanne, Rachel A. Myers, Adam H. Buchanan, David Dimmock, Kimberly G. Fulda, Irina V. Haller, Susanne B. Haga, et al. “Effect of Sociodemographic Factors on Uptake of a Patient-Facing Information Technology Family Health History Risk Assessment Platform.” Appl Clin Inform 10, no. 2 (March 2019): 180–88. https://doi.org/10.1055/s-0039-1679926.
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  - Wu, R Ryanne, Rachel A. Myers, Nina Sperber, Corrine I. Voils, Joan Neuner, Catherine A. McCarty, Irina V. Haller, et al. “Implementation, adoption, and utility of family health history risk assessment in diverse care settings: evaluating implementation processes and impact with an implementation framework.” Genet Med 21, no. 2 (February 2019): 331–38. https://doi.org/10.1038/s41436-018-0049-x.
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  - Januzzi, James L., Sunil Suchindran, Udo Hoffmann, Manesh R. Patel, Maros Ferencik, Adrian Coles, Jean-Claude Tardif, Geoffrey S. Ginsburg, Pamela S. Douglas, and Pamela S. PROMISE Investigators. “Single-Molecule hsTnI and Short-Term Risk in Stable Patients With Chest Pain.” J Am Coll Cardiol 73, no. 3 (January 29, 2019): 251–60. https://doi.org/10.1016/j.jacc.2018.10.065.
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  - Limkakeng, Alexander T., Ricardo Henao, Deepak Voora, Thomas O’Connell, Michelle Griffin, Ephraim L. Tsalik, Svati Shah, Christopher W. Woods, and Geoffrey S. Ginsburg. “Pilot study of myocardial ischemia-induced metabolomic changes in emergency department patients undergoing stress testing.” Plos One 14, no. 2 (2019): e0211762. https://doi.org/10.1371/journal.pone.0211762.
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  - Makedonas, George, Satish Mehta, Alexander Choukèr, Richard J. Simpson, Gailen Marshall, Jordan S. Orange, Serena Aunon-Chancellor, et al. “Specific Immunologic Countermeasure Protocol for Deep-Space Exploration Missions.” Front Immunol 10 (2019): 2407. https://doi.org/10.3389/fimmu.2019.02407.
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  - Lydon, Emily C., Charles Bullard, Mert Aydin, Olga M. Better, Anna Mazur, Bradly P. Nicholson, Emily R. Ko, et al. “A host gene expression approach for identifying triggers of asthma exacerbations.” Plos One 14, no. 4 (2019): e0214871. https://doi.org/10.1371/journal.pone.0214871.
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  - Fourati, Slim, Aarthi Talla, Mehrad Mahmoudian, Joshua G. Burkhart, Riku Klén, Ricardo Henao, Thomas Yu, et al. “A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection.” Nat Commun 9, no. 1 (October 24, 2018): 4418. https://doi.org/10.1038/s41467-018-06735-8.
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  - Bradley, Todd, Dimitra Peppa, Isabela Pedroza-Pacheco, Dapeng Li, Derek W. Cain, Ricardo Henao, Vaishnavi Venkat, et al. “RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.” Cell 175, no. 2 (October 4, 2018): 387-399.e17. https://doi.org/10.1016/j.cell.2018.08.064.
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  - Ginsburg, Geoffrey S., Jeanette J. McCarthy, and George P. Patrinos. “A note from the editors.” Per Med 15, no. 4 (July 1, 2018): 237–38. https://doi.org/10.2217/pme-2018-0040.
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  - Sweeney, Timothy E., Tej D. Azad, Michele Donato, Winston A. Haynes, Thanneer M. Perumal, Ricardo Henao, Jesús F. Bermejo-Martin, et al. “Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters.” Crit Care Med 46, no. 6 (June 2018): 915–25. https://doi.org/10.1097/CCM.0000000000003084.
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  - Lu, Christine Y., Stephanie Loomer, Rachel Ceccarelli, Kathleen M. Mazor, James Sabin, Ellen Wright Clayton, Geoffrey S. Ginsburg, and Ann Chen Wu. “Insurance Coverage Policies for Pharmacogenomic and Multi-Gene Testing for Cancer.” J Pers Med 8, no. 2 (May 16, 2018). https://doi.org/10.3390/jpm8020019.
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  - Ginsburg, Geoffrey S., and Kathryn A. Phillips. “Precision Medicine: From Science To Value.” Health Aff (Millwood) 37, no. 5 (May 2018): 694–701. https://doi.org/10.1377/hlthaff.2017.1624.
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  - Volpi, Simona, Carol J. Bult, Rex L. Chisholm, Patricia A. Deverka, Geoffrey S. Ginsburg, Howard J. Jacob, Melpomeni Kasapi, et al. “Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects.” Clin Pharmacol Ther 103, no. 5 (May 2018): 778–86. https://doi.org/10.1002/cpt.1048.
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  - Lu, Christine Y., Marc S. Williams, Geoffrey S. Ginsburg, Sengwee Toh, Jeff S. Brown, and Muin J. Khoury. “A proposed approach to accelerate evidence generation for genomic-based technologies in the context of a learning health system.” Genet Med 20, no. 4 (April 2018): 390–96. https://doi.org/10.1038/gim.2017.122.
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  - Sweeney, Timothy E., Thanneer M. Perumal, Ricardo Henao, Marshall Nichols, Judith A. Howrylak, Augustine M. Choi, Jesús F. Bermejo-Martin, et al. “A community approach to mortality prediction in sepsis via gene expression analysis.” Nat Commun 9, no. 1 (February 15, 2018): 694. https://doi.org/10.1038/s41467-018-03078-2.
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  - Crucian, Brian E., Alexander Choukèr, Richard J. Simpson, Satish Mehta, Gailen Marshall, Scott M. Smith, Sara R. Zwart, et al. “Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions.” Front Immunol 9 (2018): 1437. https://doi.org/10.3389/fimmu.2018.01437.
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  - Poore, Gregory D., Emily R. Ko, Ashlee Valente, Ricardo Henao, Kelsey Sumner, Christopher Hong, Thomas W. Burke, et al. “A miRNA Host Response Signature Accurately Discriminates Acute Respiratory Infection Etiologies.” Front Microbiol 9 (2018): 2957. https://doi.org/10.3389/fmicb.2018.02957.
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  - Phillips, Kathryn A., Patricia A. Deverka, Harold C. Sox, Muin J. Khoury, Lewis G. Sandy, Geoffrey S. Ginsburg, Sean R. Tunis, Lori A. Orlando, and Michael P. Douglas. “Making genomic medicine evidence-based and patient-centered: a structured review and landscape analysis of comparative effectiveness research.” Genet Med 19, no. 10 (October 2017): 1081–91. https://doi.org/10.1038/gim.2017.21.
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  - Ginsburg, Geoffrey S. “RESPONSE: Training in Precision Cardiology The Time Is Now.” Journal of the American College of Cardiology 70, no. 13 (September 26, 2017): 1678–79.
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  - Cirulli, E. T., and G. S. Ginsburg. “Studying genetic resilience to improve human health.” Oral Dis 23, no. 6 (September 2017): 685–88. https://doi.org/10.1111/odi.12567.
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  - Sperber, Nina R., Janet S. Carpenter, Larisa H. Cavallari, Laura J Damschroder, Rhonda M. Cooper-DeHoff, Joshua C. Denny, Geoffrey S. Ginsburg, et al. “Challenges and strategies for implementing genomic services in diverse settings: experiences from the Implementing GeNomics In pracTicE (IGNITE) network.” Bmc Med Genomics 10, no. 1 (May 22, 2017): 35. https://doi.org/10.1186/s12920-017-0273-2.
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  - Yang, N. Y., R. Q. Wolever, R. Roberts, A. Perlman, R. J. Dolor, D. I. Abrams, G. S. Ginsburg, and L. A. Simmons. “Integrative health care services utilization as a function of body mass index: A BraveNet practice-based research network study.” Advances in Integrative Medicine 4, no. 1 (April 1, 2017): 14–21. https://doi.org/10.1016/j.aimed.2017.02.003.
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  - Burke, Thomas W., Ricardo Henao, Erik Soderblom, Ephraim L. Tsalik, J Will Thompson, Micah T. McClain, Marshall Nichols, et al. “Nasopharyngeal Protein Biomarkers of Acute Respiratory Virus Infection.” Ebiomedicine 17 (March 2017): 172–81. https://doi.org/10.1016/j.ebiom.2017.02.015.
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  - Haga, Susanne B., Rachel Mills, Jivan Moaddeb, Nancy Allen LaPointe, Alex Cho, and Geoffrey S. Ginsburg. “Primary care providers' use of pharmacist support for delivery of pharmacogenetic testing.” Pharmacogenomics 18, no. 4 (March 2017): 359–67. https://doi.org/10.2217/pgs-2016-0177.
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  - Wang, Liuyang, Emily R. Ko, James J. Gilchrist, Kelly J. Pittman, Anna Rautanen, Matti Pirinen, J Will Thompson, et al. “Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis.” Sci Adv 3, no. 3 (March 2017): e1602096. https://doi.org/10.1126/sciadv.1602096.
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  - Sobel Leonard, Ashley, Micah T. McClain, Gavin J. D. Smith, David E. Wentworth, Rebecca A. Halpin, Xudong Lin, Amy Ransier, et al. “The effective rate of influenza reassortment is limited during human infection.” Plos Pathog 13, no. 2 (February 2017): e1006203. https://doi.org/10.1371/journal.ppat.1006203.
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  - Wu, R Ryanne, Rachel A. Myers, Elizabeth R. Hauser, Allison Vorderstrasse, Alex Cho, Geoffrey S. Ginsburg, and Lori A. Orlando. “Impact of Genetic Testing and Family Health History Based Risk Counseling on Behavior Change and Cognitive Precursors for Type 2 Diabetes.” J Genet Couns 26, no. 1 (February 2017): 133–40. https://doi.org/10.1007/s10897-016-9988-z.
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  - Voora, Deepak, Adrian Coles, Kerry L. Lee, Udo Hoffmann, James A. Wingrove, Brian Rhees, Lin Huang, et al. “An age- and sex-specific gene expression score is associated with revascularization and coronary artery disease: Insights from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial.” Am Heart J 184 (February 2017): 133–40. https://doi.org/10.1016/j.ahj.2016.11.004.
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  - Apple, Fred S., Louise Cullen, G Michael Felker, Geoffrey Ginsburg, and David Morrow. “Cardiovascular Disease: Impact of Biomarkers, Proteomics, and Genomics.” Clin Chem 63, no. 1 (January 2017): 1–4. https://doi.org/10.1373/clinchem.2016.263350.
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  - Ginsburg, Geoffrey S. “Genomics-Inspired Biomarkers and Diagnostics-Where Are They?” Clin Chem 63, no. 1 (January 2017): 255–57. https://doi.org/10.1373/clinchem.2016.266114.
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  - Yan, Qin, Sun Hee Ahn, Felix Mba Medie, Batu K. Sharma-Kuinkel, Lawrence P. Park, William K. Scott, Hitesh Deshmukh, et al. “Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans.” Plos One 12, no. 6 (2017): e0179033. https://doi.org/10.1371/journal.pone.0179033.
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  - Sobel Leonard, Ashley, Micah T. McClain, Gavin J. D. Smith, David E. Wentworth, Rebecca A. Halpin, Xudong Lin, Amy Ransier, et al. “Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification.” J Virol 90, no. 24 (December 15, 2016): 11247–58. https://doi.org/10.1128/JVI.01657-16.
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  - Ohman, E Magnus, Pamela S. Douglas, L Blue Dean, and Geoffrey S. Ginsburg. “Philanthropy for Science: Is It a Viable Option?” Circ Res 119, no. 10 (October 28, 2016): 1057–59. https://doi.org/10.1161/CIRCRESAHA.116.309657.
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  - Dzau, Victor J., and Geoffrey S. Ginsburg. “Realizing the Full Potential of Precision Medicine in Health and Health Care.” Jama 316, no. 16 (October 25, 2016): 1659–60. https://doi.org/10.1001/jama.2016.14117.
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  - Orlando, Lori A., R Ryanne Wu, Rachel A. Myers, Adam H. Buchanan, Vincent C. Henrich, Elizabeth R. Hauser, and Geoffrey S. Ginsburg. “Clinical utility of a Web-enabled risk-assessment and clinical decision support program.” Genet Med 18, no. 10 (October 2016): 1020–28. https://doi.org/10.1038/gim.2015.210.
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  - Haga, Susanne B., Rachel Mills, Jivan Moaddeb, Nancy Allen Lapointe, Alex Cho, and Geoffrey S. Ginsburg. “Patient experiences with pharmacogenetic testing in a primary care setting.” Pharmacogenomics 17, no. 15 (October 2016): 1629–36. https://doi.org/10.2217/pgs-2016-0077.
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  - Voora, Deepak, A Koneti Rao, Gauthami S. Jalagadugula, Rachel Myers, Emily Harris, Thomas L. Ortel, and Geoffrey S. Ginsburg. “Systems Pharmacogenomics Finds RUNX1 Is an Aspirin-Responsive Transcription Factor Linked to Cardiovascular Disease and Colon Cancer.” Ebiomedicine 11 (September 2016): 157–64. https://doi.org/10.1016/j.ebiom.2016.08.021.
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  - Manolio, T. A., R. Ward, and G. S. Ginsburg. “Clinical implementation of genomic medicine: the importance of global collaboration.” Expert Review of Precision Medicine and Drug Development 1, no. 4 (July 3, 2016): 349–51. https://doi.org/10.1080/23808993.2016.1192460.
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  - Williams, Janet K., Ann K. Cashion, Sam Shekar, and Geoffrey S. Ginsburg. “Genomics, clinical research, and learning health care systems: Strategies to improve patient care.” Nursing Outlook 64, no. 3 (May 2016): 225–28. https://doi.org/10.1016/j.outlook.2015.12.006.
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  - Yang, William E., Sunil Suchindran, Bradly P. Nicholson, Micah T. McClain, Thomas Burke, Geoffrey S. Ginsburg, Clayton D. Harro, et al. “Transcriptomic Analysis of the Host Response and Innate Resilience to Enterotoxigenic Escherichia coli Infection in Humans.” J Infect Dis 213, no. 9 (May 1, 2016): 1495–1504. https://doi.org/10.1093/infdis/jiv593.
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  - Mullington, Janet M., Sabra M. Abbott, Judith E. Carroll, Christopher J. Davis, Derk-Jan Dijk, David F. Dinges, Philip R. Gehrman, et al. “Developing Biomarker Arrays Predicting Sleep and Circadian-Coupled Risks to Health.” Sleep 39, no. 4 (April 1, 2016): 727–36. https://doi.org/10.5665/sleep.5616.
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  - Tsalik, Ephraim L., Yanhong Li, Lori L. Hudson, Vivian H. Chu, Tiffany Himmel, Alex T. Limkakeng, Jason N. Katz, et al. “Potential Cost-effectiveness of Early Identification of Hospital-acquired Infection in Critically Ill Patients.” Ann Am Thorac Soc 13, no. 3 (March 2016): 401–13. https://doi.org/10.1513/AnnalsATS.201504-205OC.
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  - McClain, M. T., R. Henao, J. Williams, B. Nicholson, T. Veldman, L. Hudson, E. L. Tsalik, et al. “Differential evolution of peripheral cytokine levels in symptomatic and asymptomatic responses to experimental influenza virus challenge.” Clin Exp Immunol 183, no. 3 (March 2016): 441–51. https://doi.org/10.1111/cei.12736.
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  - Liu, Tzu-Yu, Thomas Burke, Lawrence P. Park, Christopher W. Woods, Aimee K. Zaas, Geoffrey S. Ginsburg, and Alfred O. Hero. “An individualized predictor of health and disease using paired reference and target samples.” Bmc Bioinformatics 17 (January 22, 2016): 47. https://doi.org/10.1186/s12859-016-0889-9.
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  - Tsalik, Ephraim L., Ricardo Henao, Marshall Nichols, Thomas Burke, Emily R. Ko, Micah T. McClain, Lori L. Hudson, et al. “Host gene expression classifiers diagnose acute respiratory illness etiology.” Sci Transl Med 8, no. 322 (January 20, 2016): 322ra11. https://doi.org/10.1126/scitranslmed.aad6873.
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  - Shah, Svati H., Donna Arnett, Steven R. Houser, Geoffrey S. Ginsburg, Calum MacRae, Seema Mital, Joseph Loscalzo, and Jennifer L. Hall. “Opportunities for the Cardiovascular Community in the Precision Medicine Initiative.” Circulation 133, no. 2 (January 12, 2016): 226–31. https://doi.org/10.1161/CIRCULATIONAHA.115.019475.
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  - Weitzel, Kristin Wiisanen, Madeline Alexander, Barbara A. Bernhardt, Neil Calman, David J. Carey, Larisa H. Cavallari, Julie R. Field, et al. “The IGNITE network: a model for genomic medicine implementation and research.” Bmc Med Genomics 9 (January 5, 2016): 1. https://doi.org/10.1186/s12920-015-0162-5.
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  - McClain, Micah T., Bradly P. Nicholson, Lawrence P. Park, Tzu-Yu Liu, Alfred O. Hero, Ephraim L. Tsalik, Aimee K. Zaas, et al. “A Genomic Signature of Influenza Infection Shows Potential for Presymptomatic Detection, Guiding Early Therapy, and Monitoring Clinical Responses.” Open Forum Infect Dis 3, no. 1 (January 2016): ofw007. https://doi.org/10.1093/ofid/ofw007.
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  - Wu, R Ryanne, Rachel A. Myers, Catherine A. McCarty, David Dimmock, Michael Farrell, Deanna Cross, Troy D. Chinevere, Geoffrey S. Ginsburg, Lori A. Orlando, and Lori A. Family Health History Network. “Protocol for the "Implementation, adoption, and utility of family history in diverse care settings" study.” Implement Sci 10 (November 24, 2015): 163. https://doi.org/10.1186/s13012-015-0352-8.
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  - Mullington, Janet, Allan I. Pack, and Geoffrey S. Ginsburg. “In Pursuit of Sleep-Circadian Biomarkers.” Sleep 38, no. 11 (November 1, 2015): 1665–66. https://doi.org/10.5665/sleep.5132.
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  - Kraus, William E., Christopher B. Granger, Michael H. Sketch, Mark P. Donahue, Geoffrey S. Ginsburg, Elizabeth R. Hauser, Carol Haynes, et al. “A Guide for a Cardiovascular Genomics Biorepository: the CATHGEN Experience.” J Cardiovasc Transl Res 8, no. 8 (November 2015): 449–57. https://doi.org/10.1007/s12265-015-9648-y.
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  - Voils, Corrine I., Cynthia J. Coffman, Janet M. Grubber, David Edelman, Azita Sadeghpour, Matthew L. Maciejewski, Jamiyla Bolton, Alex Cho, Geoffrey S. Ginsburg, and William S. Yancy. “Does Type 2 Diabetes Genetic Testing and Counseling Reduce Modifiable Risk Factors? A Randomized Controlled Trial of Veterans.” J Gen Intern Med 30, no. 11 (November 2015): 1591–98. https://doi.org/10.1007/s11606-015-3315-5.
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  - Stafford-Smith, Mark, Yi-Ju Li, Joseph P. Mathew, Yen-Wei Li, Yunqi Ji, Barbara G. Phillips-Bute, Carmelo A. Milano, et al. “Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci.” Kidney Int 88, no. 4 (October 2015): 823–32. https://doi.org/10.1038/ki.2015.161.
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  - Tsalik, Ephraim L., Laurel K. Willig, Brandon J. Rice, Jennifer C. van Velkinburgh, Robert P. Mohney, Jonathan E. McDunn, Darrell L. Dinwiddie, et al. “Renal systems biology of patients with systemic inflammatory response syndrome.” Kidney International 88, no. 4 (October 2015): 804–14. https://doi.org/10.1038/ki.2015.150.
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  - Friede, Kevin A., Geoffrey S. Ginsburg, and Deepak Voora. “Gene Expression Signatures and the Spectrum of Coronary Artery Disease.” J Cardiovasc Transl Res 8, no. 6 (August 2015): 339–52. https://doi.org/10.1007/s12265-015-9640-6.
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  - David, Sean P., Samuel G. Johnson, Adam C. Berger, W Gregory Feero, Sharon F. Terry, Larry A. Green, Robert L. Phillips, and Geoffrey S. Ginsburg. “Making Personalized Health Care Even More Personalized: Insights From Activities of the IOM Genomics Roundtable.” Ann Fam Med 13, no. 4 (July 2015): 373–80. https://doi.org/10.1370/afm.1772.
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  - Manolio, Teri A., Marc Abramowicz, Fahd Al-Mulla, Warwick Anderson, Rudi Balling, Adam C. Berger, Steven Bleyl, et al. “Global implementation of genomic medicine: We are not alone.” Sci Transl Med 7, no. 290 (June 3, 2015): 290ps13. https://doi.org/10.1126/scitranslmed.aab0194.
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  - Dzau, Victor J., Geoffrey S. Ginsburg, Karen Van Nuys, David Agus, and Dana Goldman. “Aligning incentives to fulfil the promise of personalised medicine.” Lancet 385, no. 9982 (May 23, 2015): 2118–19. https://doi.org/10.1016/S0140-6736(15)60722-X.
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  - Katsanis, Sara Huston, Mollie A. Minear, Allison Vorderstrasse, Nancy Yang, Jason W. Reeves, Tejinder Rakhra-Burris, Robert Cook-Deegan, Geoffrey S. Ginsburg, and Leigh Ann Simmons. “Perspectives on genetic and genomic technologies in an academic medical center: the duke experience.” J Pers Med 5, no. 2 (April 3, 2015): 67–82. https://doi.org/10.3390/jpm5020067.
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  - Buchanan, Adam H., Carol A. Christianson, Tiffany Himmel, Karen P. Powell, Astrid Agbaje, Geoffrey S. Ginsburg, Vincent C. Henrich, and Lori A. Orlando. “Use of a patient-entered family health history tool with decision support in primary care: impact of identification of increased risk patients on genetic counseling attendance.” J Genet Couns 24, no. 1 (February 2015): 179–88. https://doi.org/10.1007/s10897-014-9753-0.
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  - Gallagher, Patrick, Heather A. King, Susanne B. Haga, Lori A. Orlando, Scott V. Joy, Gloria M. Trujillo, William Michael Scott, et al. “Patient beliefs and behaviors about genomic risk for type 2 diabetes: implications for prevention.” J Health Commun 20, no. 6 (2015): 728–35. https://doi.org/10.1080/10810730.2015.1018563.
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  - Vorderstrasse, Allison, Sara Huston Katsanis, Mollie A. Minear, Nancy Yang, Tejinder Rakhra-Burris, Jason W. Reeves, Robert Cook-Deegan, Geoffrey S. Ginsburg, and Leigh Ann Simmons. “Perceptions of Personalized Medicine in an Academic Health System: Educational Findings.” J Contemp Med Educ 3, no. 1 (2015): 14–19. https://doi.org/10.5455/jcme.20150408050414.
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  - Ko, Emily R., William E. Yang, Micah T. McClain, Christopher W. Woods, Geoffrey S. Ginsburg, and Ephraim L. Tsalik. “What was old is new again: using the host response to diagnose infectious disease.” Expert Rev Mol Diagn 15, no. 9 (2015): 1143–58. https://doi.org/10.1586/14737159.2015.1059278.
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  - Li, Josephine H., Sunil Suchindran, Svati H. Shah, William E. Kraus, Geoffrey S. Ginsburg, and Deepak Voora. “SLCO1B1 genetic variants, long-term low-density lipoprotein cholesterol levels and clinical events in patients following cardiac catheterization.” Pharmacogenomics 16, no. 5 (2015): 449–58. https://doi.org/10.2217/pgs.15.2.
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  - Rose, Jason J., Deepak Voora, Derek D. Cyr, Joseph E. Lucas, Aimee K. Zaas, Christopher W. Woods, L Kristin Newby, William E. Kraus, and Geoffrey S. Ginsburg. “Gene Expression Profiles Link Respiratory Viral Infection, Platelet Response to Aspirin, and Acute Myocardial Infarction.” Plos One 10, no. 7 (2015): e0132259. https://doi.org/10.1371/journal.pone.0132259.
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  - Suchindran, Sunil, Tiffany Himmel, Thomas L. Ortel, Richard C. Becker, William E. Kraus, L. K. Newby, Geoffrey S. Ginsburg, and Deepak Voora. “Aspirin-Responsive Platelet Genes Are Associated With Platelet Function and Cardiovascular Events.” Circulation 130 (November 25, 2014).
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  - Zaas, Aimee K., Bronwen H. Garner, Ephraim L. Tsalik, Thomas Burke, Christopher W. Woods, and Geoffrey S. Ginsburg. “The current epidemiology and clinical decisions surrounding acute respiratory infections.” Trends Mol Med 20, no. 10 (October 2014): 579–88. https://doi.org/10.1016/j.molmed.2014.08.001.
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  - Haga, Susanne B., Nancy M Allen LaPointe, Alex Cho, Shelby D. Reed, Rachel Mills, Jivan Moaddeb, and Geoffrey S. Ginsburg. “Pilot study of pharmacist-assisted delivery of pharmacogenetic testing in a primary care setting.” Pharmacogenomics 15, no. 13 (September 2014): 1677–86. https://doi.org/10.2217/pgs.14.109.
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  - Benjamin, Ashlee M., Marshall Nichols, Thomas W. Burke, Geoffrey S. Ginsburg, and Joseph E. Lucas. “Comparing reference-based RNA-Seq mapping methods for non-human primate data.” Bmc Genomics 15 (July 7, 2014): 570. https://doi.org/10.1186/1471-2164-15-570.
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  - Stevenson, Marvaretta, Jared Christensen, Debra Shoemaker, Traci Foster, William T. Barry, Betty C. Tong, Momen Wahidi, et al. “Tumor acquisition for biomarker research in lung cancer.” Cancer Invest 32, no. 6 (July 2014): 291–98. https://doi.org/10.3109/07357907.2014.911880.
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  - Beadles, Chris A., R. Ryanne Wu, Tiffany Himmel, Adam H. Buchanan, Karen P. Powell, Elizabeth Hauser, Vincent C. Henrich, Geoffrey S. Ginsburg, and Lori A. Orlando. “Providing patient education: impact on quantity and quality of family health history collection.” Fam Cancer 13, no. 2 (June 2014): 325–32. https://doi.org/10.1007/s10689-014-9701-z.
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  - Kraft, Bryan D., Claude A. Piantadosi, Ashlee M. Benjamin, Joseph E. Lucas, Aimee K. Zaas, Marisol Betancourt-Quiroz, Christopher W. Woods, et al. “Development of a novel preclinical model of pneumococcal pneumonia in nonhuman primates.” Am J Respir Cell Mol Biol 50, no. 5 (May 2014): 995–1004. https://doi.org/10.1165/rcmb.2013-0340OC.
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  - Ngo, Hoan T., Hsin-Neng Wang, Thomas Burke, Geoffrey S. Ginsburg, and Tuan Vo-Dinh. “Multiplex detection of disease biomarkers using SERS molecular sentinel-on-chip.” Anal Bioanal Chem 406, no. 14 (May 2014): 3335–44. https://doi.org/10.1007/s00216-014-7648-4.
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  - Power, Aidan, Adam C. Berger, and Geoffrey S. Ginsburg. “Genomics-enabled drug repositioning and repurposing: insights from an IOM Roundtable activity.” Jama 311, no. 20 (May 2014): 2063–64. https://doi.org/10.1001/jama.2014.3002.
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  - Ginsburg, Geoffrey. “Medical genomics: Gather and use genetic data in health care.” Nature 508, no. 7497 (April 24, 2014): 451–53. https://doi.org/10.1038/508451a.
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  - Kertai, Miklos D., Stephen A. Esper, Igor Akushevich, Deepak Voora, Geoffrey S. Ginsburg, Mark Stafford-Smith, Katherine Grichnik, et al. “Preoperative CYP2D6 metabolism-dependent β-blocker use and mortality after coronary artery bypass grafting surgery.” J Thorac Cardiovasc Surg 147, no. 4 (April 2014): 1368-1375.e3. https://doi.org/10.1016/j.jtcvs.2013.09.067.
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  - Li, Josephine H., Scott V. Joy, Susanne B. Haga, Lori A. Orlando, William E. Kraus, Geoffrey S. Ginsburg, and Deepak Voora. “Genetically guided statin therapy on statin perceptions, adherence, and cholesterol lowering: a pilot implementation study in primary care patients.” J Pers Med 4, no. 2 (March 27, 2014): 147–62. https://doi.org/10.3390/jpm4020147.
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  - Hudson, Lori L., Christopher W. Woods, and Geoffrey S. Ginsburg. “A novel diagnostic approach may reduce inappropriate antibiotic use for acute respiratory infections.” Expert Rev Anti Infect Ther 12, no. 3 (March 2014): 279–82. https://doi.org/10.1586/14787210.2014.881717.
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  - Orlando, Lori A., R Ryanne Wu, Chris Beadles, Tiffany Himmel, Adam H. Buchanan, Karen P. Powell, Elizabeth R. Hauser, Vincent C. Henrich, and Geoffrey S. Ginsburg. “Implementing family health history risk stratification in primary care: impact of guideline criteria on populations and resource demand.” Am J Med Genet C Semin Med Genet 166C, no. 1 (March 2014): 24–33. https://doi.org/10.1002/ajmg.c.31388.
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  - Wu, R Ryanne, Tiffany L. Himmel, Adam H. Buchanan, Karen P. Powell, Elizabeth R. Hauser, Geoffrey S. Ginsburg, Vincent C. Henrich, and Lori A. Orlando. “Quality of family history collection with use of a patient facing family history assessment tool.” Bmc Fam Pract 15 (February 13, 2014): 31. https://doi.org/10.1186/1471-2296-15-31.
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  - Haga, S. B., W. T. Barry, R. Mills, L. Svetkey, S. Suchindran, H. F. Willard, and G. S. Ginsburg. “Impact of delivery models on understanding genomic risk for type 2 diabetes.” Public Health Genomics 17, no. 2 (2014): 95–104. https://doi.org/10.1159/000358413.
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  - Tsalik, Ephraim L., Raymond J. Langley, Darrell L. Dinwiddie, Neil A. Miller, Byunggil Yoo, Jennifer C. van Velkinburgh, Laurie D. Smith, et al. “An integrated transcriptome and expressed variant analysis of sepsis survival and death.” Genome Med 6, no. 11 (2014): 111. https://doi.org/10.1186/s13073-014-0111-5.
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  - Voora, Deepak, Geoffrey S. Ginsburg, and Axel Akerblom. “Platelet RNA as a novel biomarker for the response to antiplatelet therapy.” Future Cardiol 10, no. 1 (January 2014): 9–12. https://doi.org/10.2217/fca.13.90.
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  - Wu, R. R., T. L. Himmel, A. H. Buchanan, K. P. Powell, E. R. Hauser, G. S. Ginsburg, V. C. Henrich, and L. A. Orlando. “Quality of family history collection with use of a patient facing family history assessment tool.” Bmc Family Practice 15, no. 1 (2014). https://doi.org/10.1186/1471-2296-15-31.
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  - Xing, Z., B. Nicholson, M. Jimenez, T. Veldman, L. Hudson, J. Lucas, D. Dunson, et al. “Bayesian modeling of temporal properties of infectious disease in a college student population.” Journal of Applied Statistics 41, no. 6 (January 1, 2014): 1358–82. https://doi.org/10.1080/02664763.2013.870138.
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  - McClain, Micah T., Lawrence P. Park, Bradly Nicholson, Timothy Veldman, Aimee K. Zaas, Ron Turner, Robert Lambkin-Williams, Anthony S. Gilbert, Geoffrey S. Ginsburg, and Christopher W. Woods. “Longitudinal analysis of leukocyte differentials in peripheral blood of patients with acute respiratory viral infections.” J Clin Virol 58, no. 4 (December 2013): 689–95. https://doi.org/10.1016/j.jcv.2013.09.015.
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  - Katsanis, Sara H., Jennifer R. Dungan, Catherine L. Gilliss, and Geoffrey A. Ginsburg. “Educating future providers of personalized medicine.” N C Med J 74, no. 6 (November 2013): 491–92.
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  - Cohen, Matan J., Geoffrey S. Ginsburg, Edward Abrahams, Haim Bitterman, and Eddy Karnieli. “Overcoming barriers in the implementation of personalized medicine into clinical practice.” Isr Med Assoc J 15, no. 10 (October 2013): 599–601.
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  - Voora, Deepak, Derek Cyr, Joseph Lucas, Jen-Tsan Chi, Jennifer Dungan, Timothy A. McCaffrey, Richard Katz, et al. “Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events.” J Am Coll Cardiol 62, no. 14 (October 1, 2013): 1267–76. https://doi.org/10.1016/j.jacc.2013.05.073.
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  - Zaas, Aimee K., Thomas Burke, Minhua Chen, Micah McClain, Bradly Nicholson, Timothy Veldman, Ephraim L. Tsalik, et al. “A host-based RT-PCR gene expression signature to identify acute respiratory viral infection.” Sci Transl Med 5, no. 203 (September 18, 2013): 203ra126. https://doi.org/10.1126/scitranslmed.3006280.
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  - Manolio, Teri A., Rex L. Chisholm, Brad Ozenberger, Dan M. Roden, Marc S. Williams, Richard Wilson, David Bick, et al. “Implementing Genomic Medicine in the Clinic: The Future Is Here EDITORIAL COMMENT.” Obstetrical & Gynecological Survey 68, no. 9 (September 1, 2013): 621–23.
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  - Ginsburg, G. S. “Application of Human Genome Information to Clinical Practice” 1 (August 29, 2013): 204–15. https://doi.org/10.1016/B978-0-12-382227-7.00017-3.
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  - Ginsburg, G., and H. Willard. “Genomic and Personalized Medicine.” Genomic and Personalized Medicine 1–2 (August 26, 2013).
  - Wu, R Ryanne, Lori A. Orlando, Tiffany L. Himmel, Adam H. Buchanan, Karen P. Powell, Elizabeth R. Hauser, Astrid B. Agbaje, Vincent C. Henrich, and Geoffrey S. Ginsburg. “Patient and primary care provider experience using a family health history collection, risk stratification, and clinical decision support tool: a type 2 hybrid controlled implementation-effectiveness trial.” Bmc Fam Pract 14 (August 6, 2013): 111. https://doi.org/10.1186/1471-2296-14-111.
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  - Vorderstrasse, Allison A., Alex Cho, Corrine I. Voils, Lori A. Orlando, and Geoffrey S. Ginsburg. “Clinical utility of genetic risk testing in primary care: the example of Type 2 diabetes.” Per Med 10, no. 6 (August 2013): 549–63. https://doi.org/10.2217/pme.13.47.
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  - Langley, Raymond J., Ephraim L. Tsalik, Jennifer C. van Velkinburgh, Seth W. Glickman, Brandon J. Rice, Chunping Wang, Bo Chen, et al. “An integrated clinico-metabolomic model improves prediction of death in sepsis.” Sci Transl Med 5, no. 195 (July 24, 2013): 195ra95. https://doi.org/10.1126/scitranslmed.3005893.
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  - Wang, Hsin-Neng, Andrew M. Fales, Aimee K. Zaas, Christopher W. Woods, Thomas Burke, Geoffrey S. Ginsburg, and Tuan Vo-Dinh. “Surface-enhanced Raman scattering molecular sentinel nanoprobes for viral infection diagnostics.” Anal Chim Acta 786 (July 5, 2013): 153–58. https://doi.org/10.1016/j.aca.2013.05.017.
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  - Simonds, Naoko I., Muin J. Khoury, Sheri D. Schully, Katrina Armstrong, Wendy F. Cohn, David A. Fenstermacher, Geoffrey S. Ginsburg, et al. “Comparative effectiveness research in cancer genomics and precision medicine: current landscape and future prospects.” J Natl Cancer Inst 105, no. 13 (July 3, 2013): 929–36. https://doi.org/10.1093/jnci/djt108.
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  - Orlando, Lori A., Adam H. Buchanan, Susan E. Hahn, Carol A. Christianson, Karen P. Powell, Celette Sugg Skinner, Blair Chesnut, et al. “Development and validation of a primary care-based family health history and decision support program (MeTree).” N C Med J 74, no. 4 (July 2013): 287–96.
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  - Powell, Karen P., Carol A. Christianson, Susan E. Hahn, Gaurav Dave, Leslie R. Evans, Susan H. Blanton, Elizabeth Hauser, et al. “Collection of family health history for assessment of chronic disease risk in primary care.” N C Med J 74, no. 4 (July 2013): 279–86.
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  - McCarthy, Jeanette J., Howard L. McLeod, and Geoffrey S. Ginsburg. “Genomic medicine: a decade of successes, challenges, and opportunities.” Sci Transl Med 5, no. 189 (June 12, 2013): 189sr4. https://doi.org/10.1126/scitranslmed.3005785.
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  - Henao, R., J. W. Thompson, M. A. Moseley, G. S. Ginsburg, L. Carin, and J. E. Lucas. “Latent protein trees.” Annals of Applied Statistics 7, no. 2 (June 1, 2013): 691–713. https://doi.org/10.1214/13-AOAS639.
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  - Tenenbaum, Jay M Marty, Amy P. Abernethy, Abhijit Ron Mazumder, and Geoffrey S. Ginsburg. “The Impact of Personalized Medicine.” Scientist 27, no. 6 (June 1, 2013): 64–65.
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  - Orlando, Lori A., Vincent C. Henrich, Elizabeth R. Hauser, Charles Wilson, Geoffrey S. Ginsburg, and Geoffrey S. Genomedical Connection. “The genomic medicine model: an integrated approach to implementation of family health history in primary care.” Per Med 10, no. 3 (May 2013): 295–306. https://doi.org/10.2217/pme.13.20.
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  - Vorderstrasse, Allison A., Geoffrey S. Ginsburg, William E. Kraus, Maj Carlos J. Maldonado, and Ruth Q. Wolever. “Health coaching and genomics-potential avenues to elicit behavior change in those at risk for chronic disease: protocol for personalized medicine effectiveness study in air force primary care.” Glob Adv Health Med 2, no. 3 (May 2013): 26–38. https://doi.org/10.7453/gahmj.2013.035.
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  - Ginsburg, Geoffrey S. “Realizing the opportunities of genomics in health care.” Jama 309, no. 14 (April 10, 2013): 1463–64. https://doi.org/10.1001/jama.2013.1465.
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  - Haga, Susanne B., William T. Barry, Rachel Mills, Geoffrey S. Ginsburg, Laura Svetkey, Jennifer Sullivan, and Huntington F. Willard. “Public knowledge of and attitudes toward genetics and genetic testing.” Genet Test Mol Biomarkers 17, no. 4 (April 2013): 327–35. https://doi.org/10.1089/gtmb.2012.0350.
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  - Khoury, Muin J., Tram Kim Lam, John P. A. Ioannidis, Patricia Hartge, Margaret R. Spitz, Julie E. Buring, Stephen J. Chanock, et al. “Transforming epidemiology for 21st century medicine and public health.” Cancer Epidemiol Biomarkers Prev 22, no. 4 (April 2013): 508–16. https://doi.org/10.1158/1055-9965.EPI-13-0146.
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  - Manolio, Teri A., Rex L. Chisholm, Brad Ozenberger, Dan M. Roden, Marc S. Williams, Richard Wilson, David Bick, et al. “Implementing genomic medicine in the clinic: the future is here.” Genetics in Medicine : Official Journal of the American College of Medical Genetics 15, no. 4 (April 2013): 258–67. https://doi.org/10.1038/gim.2012.157.
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  - Bazot, Cécile, Nicolas Dobigeon, Jean-Yves Tourneret, Aimee K. Zaas, Geoffrey S. Ginsburg, and Alfred O. Hero. “Unsupervised Bayesian linear unmixing of gene expression microarrays.” Bmc Bioinformatics 14 (March 19, 2013): 99. https://doi.org/10.1186/1471-2105-14-99.
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  - Haga, S. B., W. Burke, G. S. Ginsburg, R. Mills, and R. Agans. “Primary care physicians' knowledge of and experience with pharmacogenetic testing.” Obstetrical and Gynecological Survey 68, no. 2 (February 1, 2013): 91–93. https://doi.org/10.1097/01.ogx.0000427617.89027.ca.
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  - Yang, N., G. S. Ginsburg, and L. A. Simmons. “Personalized medicine in women's obesity prevention and treatment: implications for research, policy and practice.” Obes Rev 14, no. 2 (February 2013): 145–61. https://doi.org/10.1111/j.1467-789X.2012.01048.x.
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  - Ahn, Sun Hee, Ephraim L. Tsalik, Derek D. Cyr, Yurong Zhang, Jennifer C. van Velkinburgh, Raymond J. Langley, Seth W. Glickman, et al. “Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans.” Plos One 8, no. 1 (2013): e48979. https://doi.org/10.1371/journal.pone.0048979.
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  - Henao, Ricardo, Jared Murray, Geoffrey Ginsburg, Lawrence Carin, and Joseph E. Lucas. “Patient clustering with uncoded text in electronic medical records.” Amia Annu Symp Proc 2013 (2013): 592–99.
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  - Manolio, T. A., R. L. Chisholm, B. Ozenberger, D. M. Roden, M. S. Williams, R. Wilson, D. Bick, et al. “Implementing genomic medicine in the clinic: The future is here.” Obstetrical and Gynecological Survey 68, no. 9 (2013): 621–23. https://doi.org/10.1097/01.ogx.0000435523.89711.77.
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  - Rose, J. J., D. Voora, D. D. Cyr, J. E. Lucas, A. K. Zaas, L. K. Newby, W. E. Kraus, and G. S. Ginsburg. “Blood Gene Expression Profiling Reveals An Association Between Viral Infection, Platelet Function, And Acute Myocardial Infarction.” American Journal of Respiratory and Critical Care Medicine 187 (January 1, 2013).
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  - Xing, Z., B. Nicholson, M. Jimenez, T. Veldman, L. Hudson, J. Lucas, D. Dunson, et al. “Bayesian modeling of temporal properties of infectious disease in a college student population.” Journal of Applied Statistics, 2013.
  - Woods, Christopher W., Micah T. McClain, Minhua Chen, Aimee K. Zaas, Bradly P. Nicholson, Jay Varkey, Timothy Veldman, et al. “A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2.” Plos One 8, no. 1 (2013): e52198. https://doi.org/10.1371/journal.pone.0052198.
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  - Kuderer, N. M., W. T. Barry, J. Geradts, G. S. Ginsburg, G. H. Lyman, M. Datto, V. Liotcheva, et al. “Abstract P2-10-03: A cross-platform comparison of genomic signatures and OncotypeDx score to discover potential prognostic/predictive genes and pathways.” Poster Session Abstracts, December 15, 2012. https://doi.org/10.1158/0008-5472.sabcs12-p2-10-03.
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  - Lyman, G. H., E. Culakova, M. S. Poniewierski, A. F. Wogu, W. Barry, G. S. Ginsburg, P. K. Marcom, et al. “Abstract P3-06-07: Ki67 as a Predictive Marker of Response to Neoadjuvant Chemotherapy in Patients with Early-Stage Breast Cancer (ESBC): A Systematic Review and Evidence Summary.” Poster Session Abstracts, December 15, 2012. https://doi.org/10.1158/0008-5472.sabcs12-p3-06-07.
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  - Ginsburg, Geoffrey S., and Nicole M. Kuderer. “Comparative effectiveness research, genomics-enabled personalized medicine, and rapid learning health care: a common bond.” J Clin Oncol 30, no. 34 (December 1, 2012): 4233–42. https://doi.org/10.1200/JCO.2012.42.6114.
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  - Ginsburg, Geoffrey S., and Christopher W. Woods. “The host response to infection: advancing a novel diagnostic paradigm.” Crit Care 16, no. 6 (November 6, 2012): 168. https://doi.org/10.1186/cc11685.
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  - Haga, S. B., W. Burke, G. S. Ginsburg, R. Mills, and R. Agans. “Primary care physicians' knowledge of and experience with pharmacogenetic testing.” Clin Genet 82, no. 4 (October 2012): 388–94. https://doi.org/10.1111/j.1399-0004.2012.01908.x.
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  - Mills, Rachel A., Susanne B. Haga, and Geoffrey S. Ginsburg. “Genetic testing: clinical and personal utility.” Virtual Mentor 14, no. 8 (August 1, 2012): 604–9. https://doi.org/10.1001/virtualmentor.2012.14.8.ecas1-1208.
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  - Voils, Corrine I., Cynthia J. Coffman, David Edelman, Matthew L. Maciejewski, Janet M. Grubber, Azita Sadeghpour, Alex Cho, et al. “Examining the impact of genetic testing for type 2 diabetes on health behaviors: study protocol for a randomized controlled trial.” Trials 13 (August 1, 2012): 121. https://doi.org/10.1186/1745-6215-13-121.
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  - Voora, Deepak, and Geoffrey S. Ginsburg. “Clinical application of cardiovascular pharmacogenetics.” J Am Coll Cardiol 60, no. 1 (July 3, 2012): 9–20. https://doi.org/10.1016/j.jacc.2012.01.067.
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  - Cho, Alex H., Ley A. Killeya-Jones, Sunil Suchindran, Julianne M. O’Daniel, Kensaku Kawamoto, Susanne Haga, Joseph E. Lucas, Gloria M. Trujillo, Scott Joy, and Geoffrey S. Ginsburg. “PRELIMINARY OUTCOMES OF GENETIC RISK TESTING IN PRIMARY CARE FOR COMMON DNA VARIANTS ASSOCIATED WITH TYPE 2 DIABETES.” Journal of General Internal Medicine 27 (July 1, 2012): S278–S278.
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  - Kraus, William E., Susanne B. Haga, Howard L. McLeod, Judd Staples, and Geoffrey S. Ginsburg. “Conference Scene: Is personalized medicine ready for prime time?” Per Med 9, no. 5 (July 2012): 475–78. https://doi.org/10.2217/pme.12.57.
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  - Henao, R., J. W. Thompson, M. A. Moseley, G. S. Ginsburg, L. Carin, and J. E. Lucas. “Hierarchical factor modeling of proteomics data.” 2012 Ieee 2nd International Conference on Computational Advances in Bio and Medical Sciences, Iccabs 2012, May 8, 2012. https://doi.org/10.1109/ICCABS.2012.6182638.
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  - Eng, G., A. Chen, T. Vess, and G. S. Ginsburg. “Genome technologies and personalized dental medicine.” Oral Dis 18, no. 3 (April 2012): 223–35. https://doi.org/10.1111/j.1601-0825.2011.01876.x.
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  - Voora, Deepak, Thomas L. Ortel, Joseph E. Lucas, Jen-Tsan Chi, Richard C. Becker, and Geoffrey S. Ginsburg. “Time-dependent changes in non-COX-1-dependent platelet function with daily aspirin therapy.” J Thromb Thrombolysis 33, no. 3 (April 2012): 246–57. https://doi.org/10.1007/s11239-012-0683-0.
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  - Zarco, M. F., T. J. Vess, and G. S. Ginsburg. “The oral microbiome in health and disease and the potential impact on personalized dental medicine.” Oral Dis 18, no. 2 (March 2012): 109–20. https://doi.org/10.1111/j.1601-0825.2011.01851.x.
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  - Cho, Alex H., Ley A. Killeya-Jones, Julianne M. O’Daniel, Kensaku Kawamoto, Patrick Gallagher, Susanne Haga, Joseph E. Lucas, Gloria M. Trujillo, Scott V. Joy, and Geoffrey S. Ginsburg. “Effect of genetic testing for risk of type 2 diabetes mellitus on health behaviors and outcomes: study rationale, development and design.” Bmc Health Serv Res 12 (January 18, 2012): 16. https://doi.org/10.1186/1472-6963-12-16.
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  - Bhattacharya, Sayanti, Ashley A. Dunham, Melissa A. Cornish, Victoria A. Christian, Geoffrey S. Ginsburg, Jessica D. Tenenbaum, Meredith L. Nahm, et al. “The Measurement to Understand Reclassification of Disease of Cabarrus/Kannapolis (MURDOCK) Study Community Registry and Biorepository.” Am J Transl Res 4, no. 4 (2012): 458–70.
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  - Carin, Lawrence, Alfred Hero, Joseph Lucas, David Dunson, Minhua Chen, Ricardo Heñao, Arnau Tibau-Puig, Aimee Zaas, Christopher W. Woods, and Geoffrey S. Ginsburg. “High-Dimensional Longitudinal Genomic Data: An analysis used for monitoring viral infections.” Ieee Signal Process Mag 29, no. 1 (January 1, 2012): 108–23. https://doi.org/10.1109/MSP.2011.943009.
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  - Ginsburg, G. S. “Application of Molecular Technologies to Clinical Medicine” 1 (January 1, 2012): 199–203. https://doi.org/10.1016/B978-1-4377-1604-7.00042-7.
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  - Tenenbaum, Jessica D., Victoria Christian, Melissa A. Cornish, Rowena J. Dolor, Ashley A. Dunham, Geoffrey S. Ginsburg, Virginia B. Kraus, et al. “The MURDOCK Study: a long-term initiative for disease reclassification through advanced biomarker discovery and integration with electronic health records.” Am J Transl Res 4, no. 3 (2012): 291–301.
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  - Culakova, E., M. S. Poniewierski, M. Huang, N. M. Kuderer, G. S. Ginsburg, W. Barry, P. K. Marcom, N. Ready, A. Abernethy, and G. H. Lyman. “P3-14-04: Assessment of Genomic Prognostic Signatures as Predictors of Response to Neoadjuvant Chemotherapy in Patients with Early Stage Breast Cancer.” Poster Session Abstracts, December 15, 2011. https://doi.org/10.1158/0008-5472.sabcs11-p3-14-04.
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  - Lewis, Deborah A., Gregg J. Stashenko, Olga M. Akay, Lulit I. Price, Kouros Owzar, Geoffrey S. Ginsburg, Jen-Tsan Chi, and Thomas L. Ortel. “Whole blood gene expression analyses in patients with single versus recurrent venous thromboembolism.” Thromb Res 128, no. 6 (December 2011): 536–40. https://doi.org/10.1016/j.thromres.2011.06.003.
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  - Orlando, Lori A., Elizabeth R. Hauser, Carol Christianson, Karen P. Powell, Adam H. Buchanan, Blair Chesnut, Astrid B. Agbaje, Vincent C. Henrich, and Geoffrey Ginsburg. “Protocol for implementation of family health history collection and decision support into primary care using a computerized family health history system.” Bmc Health Serv Res 11 (October 11, 2011): 264. https://doi.org/10.1186/1472-6963-11-264.
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  - Haga, Susanne B., Kensaku Kawamoto, Robert Agans, and Geoffrey S. Ginsburg. “Consideration of patient preferences and challenges in storage and access of pharmacogenetic test results.” Genet Med 13, no. 10 (October 2011): 887–90. https://doi.org/10.1097/GIM.0b013e31822077a5.
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  - Ginsburg, Geoffrey S., Judd Staples, and Amy P. Abernethy. “Academic medical centers: ripe for rapid-learning personalized health care.” Sci Transl Med 3, no. 101 (September 21, 2011): 101cm27. https://doi.org/10.1126/scitranslmed.3002386.
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  - Haga, Susanne B., Madeline M. Carrig, Julianne M. O’Daniel, Lori A. Orlando, Ley A. Killeya-Jones, Geoffrey S. Ginsburg, and Alex Cho. “Genomic risk profiling: attitudes and use in personal and clinical care of primary care physicians who offer risk profiling.” J Gen Intern Med 26, no. 8 (August 2011): 834–40. https://doi.org/10.1007/s11606-011-1651-7.
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  - Huang, Yongsheng, Aimee K. Zaas, Arvind Rao, Nicolas Dobigeon, Peter J. Woolf, Timothy Veldman, N Christine Øien, et al. “Temporal dynamics of host molecular responses differentiate symptomatic and asymptomatic influenza a infection.” Plos Genet 7, no. 8 (August 2011): e1002234. https://doi.org/10.1371/journal.pgen.1002234.
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  - Voora, Deepak, and Geoffrey S. Ginsburg. “A hub for bench-to-bedside pharmacogenomic-based research.” Pharmacogenomics 12, no. 8 (August 2011): 1095–98. https://doi.org/10.2217/pgs.11.62.
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  - Jing, Linhong, Carol E. Parker, David Seo, Maria Warren Hines, Nedyalka Dicheva, Yanbao Yu, Debra Schwinn, Geoffrey S. Ginsburg, and Xian Chen. “Discovery of biomarker candidates for coronary artery disease from an APOE-knock out mouse model using iTRAQ-based multiplex quantitative proteomics.” Proteomics 11, no. 14 (July 2011): 2763–76. https://doi.org/10.1002/pmic.201000202.
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  - Patel, Keyur, Joseph E. Lucas, J Will Thompson, Laura G. Dubois, Hans L. Tillmann, Alexander J. Thompson, Diane Uzarski, et al. “High predictive accuracy of an unbiased proteomic profile for sustained virologic response in chronic hepatitis C patients.” Hepatology 53, no. 6 (June 2011): 1809–18. https://doi.org/10.1002/hep.24284.
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  - Kuderer, N. M., E. Culakova, M. Huang, M. S. Poniewierski, G. S. Ginsburg, W. T. Barry, P. K. Marcom, N. Ready, A. P. Abernethy, and G. H. Lyman. “Quality appraisal of clinical validation studies for multigene prediction assays of chemotherapy response in early-stage breast cancer.” Journal of Clinical Oncology 29, no. 15_suppl (May 20, 2011): 3082–3082. https://doi.org/10.1200/jco.2011.29.15_suppl.3082.
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  - Kuderer, N. M., E. Culakova, M. Huang, M. S. Poniewierski, G. S. Ginsburg, W. T. Barry, P. K. Marcom, N. Ready, A. P. Abernethy, and G. H. Lyman. “Quality appraisal of clinical validation studies for multigene prediction assays of chemotherapy response in early-stage breast cancer.” J Clin Oncol 29, no. 15_suppl (May 20, 2011): 3082.
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  - Elashoff, Michael R., James A. Wingrove, Philip Beineke, Susan E. Daniels, Whittemore G. Tingley, Steven Rosenberg, Szilard Voros, et al. “Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients.” Bmc Med Genomics 4 (March 28, 2011): 26. https://doi.org/10.1186/1755-8794-4-26.
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  - Chen, Minhua, David Carlson, Aimee Zaas, Christopher W. Woods, Geoffrey S. Ginsburg, Alfred Hero, Joseph Lucas, and Lawrence Carin. “Detection of viruses via statistical gene expression analysis.” Ieee Trans Biomed Eng 58, no. 3 (March 2011): 468–79. https://doi.org/10.1109/TBME.2010.2059702.
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  - Tenenbaum, Jessica D., Patricia L. Whetzel, Kent Anderson, Charles D. Borromeo, Ivo D. Dinov, Davera Gabriel, Beth Kirschner, et al. “The Biomedical Resource Ontology (BRO) to enable resource discovery in clinical and translational research.” J Biomed Inform 44, no. 1 (February 2011): 137–45. https://doi.org/10.1016/j.jbi.2010.10.003.
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  - Chan, Isaac S., and Geoffrey S. Ginsburg. “Personalized medicine: progress and promise.” Annu Rev Genomics Hum Genet 12 (2011): 217–44. https://doi.org/10.1146/annurev-genom-082410-101446.
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  - Chen, Minhua, Aimee Zaas, Christopher Woods, Geoffrey S. Ginsburg, Joseph Lucas, David Dunson, and Lawrence Carin. “Predicting Viral Infection From High-Dimensional Biomarker Trajectories.” J Am Stat Assoc 106, no. 496 (January 1, 2011): 1259–79. https://doi.org/10.1198/jasa.2011.ap10611.
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  - Puig, A. T., A. Wiesel, A. K. Zaas, C. W. Woods, G. S. Ginsburg, G. Fleury, and A. O. Hero. “Order-preserving factor analysis-application to longitudinal gene expression.” Ieee Transactions on Signal Processing 59, no. 9 (January 1, 2011): 4447–58. https://doi.org/10.1109/TSP.2011.2157146.
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  - Moody, M Anthony, Ruijun Zhang, Emmanuel B. Walter, Christopher W. Woods, Geoffrey S. Ginsburg, Micah T. McClain, Thomas N. Denny, et al. “H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination.” Plos One 6, no. 10 (2011): e25797. https://doi.org/10.1371/journal.pone.0025797.
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  - Puig, A. T., A. Wiesel, A. Zaas, G. S. Ginsburg, G. Fleury, and A. O. Hero. “Order-preserving factor discovery from misaligned data.” 2010 Ieee Sensor Array and Multichannel Signal Processing Workshop, Sam 2010, December 20, 2010, 209–12. https://doi.org/10.1109/SAM.2010.5606736.
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  - Ginsburg, G. S. “Translational Genomics. From Discovery to Clinical Practice.,” December 1, 2010, 163–74. https://doi.org/10.1016/B978-0-12-374934-5.00014-3.
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  - Ginsburg, G. S., and H. F. Willard. “The Foundations of Genomic and Personalized Medicine,” December 1, 2010, 1–10. https://doi.org/10.1016/B978-0-12-374934-5.00001-5.
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  - Voora, Deepak, Thomas L. Ortel, Joseph E. Lucas, Jen-Tsan Chi, Richard C. Becker, and Geoffrey S. Ginsburg. “A Whole Blood RNA Signature Accurately Classifies Multiple Measures of Platelet Function on Aspirin in Healthy Volunteers and Highlights a Common Underlying Pathway.” Circulation 122, no. 21 (November 23, 2010).
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  - Freedman, Andrew N., Leah B. Sansbury, William D. Figg, Arnold L. Potosky, Sheila R. Weiss Smith, Muin J. Khoury, Stefanie A. Nelson, et al. “Cancer pharmacogenomics and pharmacoepidemiology: setting a research agenda to accelerate translation.” J Natl Cancer Inst 102, no. 22 (November 17, 2010): 1698–1705. https://doi.org/10.1093/jnci/djq390.
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  - Chen, Bo, Minhua Chen, John Paisley, Aimee Zaas, Christopher Woods, Geoffrey S. Ginsburg, Alfred Hero, Joseph Lucas, David Dunson, and Lawrence Carin. “Bayesian inference of the number of factors in gene-expression analysis: application to human virus challenge studies.” Bmc Bioinformatics 11 (November 9, 2010): 552. https://doi.org/10.1186/1471-2105-11-552.
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  - Altshuler, Jill S., Erin Balogh, Anna D. Barker, Stephen L. Eck, Stephen H. Friend, Geoffrey S. Ginsburg, Roy S. Herbst, Sharyl J. Nass, Christopher M. Streeter, and John A. Wagner. “Opening up to precompetitive collaboration.” Sci Transl Med 2, no. 52 (October 6, 2010): 52cm26. https://doi.org/10.1126/scitranslmed.3001515.
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  - Paisley, J., A. Zaas, C. W. Woods, G. S. Ginsburg, and L. Carin. “A stick-breaking construction of the beta process.” Icml 2010 Proceedings, 27th International Conference on Machine Learning, September 17, 2010, 847–54.
  - Ginsburg, Geoffrey S., and Deepak Voora. “The long and winding road to warfarin pharmacogenetic testing.” J Am Coll Cardiol 55, no. 25 (June 22, 2010): 2813–15. https://doi.org/10.1016/j.jacc.2010.04.006.
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  - Barry, William T., Dawn N. Kernagis, Holly K. Dressman, Ryan J. Griffis, J’vonne D. Hunter, John A. Olson, Jeff R. Marks, et al. “Intratumor heterogeneity and precision of microarray-based predictors of breast cancer biology and clinical outcome.” J Clin Oncol 28, no. 13 (May 1, 2010): 2198–2206. https://doi.org/10.1200/JCO.2009.26.7245.
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  - Suchindran, Sunil, David Rivedal, John R. Guyton, Tom Milledge, Xiaoyi Gao, Ashlee Benjamin, Jennifer Rowell, Geoffrey S. Ginsburg, and Jeanette J. McCarthy. “Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.” Plos Genet 6, no. 4 (April 29, 2010): e1000928. https://doi.org/10.1371/journal.pgen.1000928.
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  - Shah, Svati H., James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, David R. Crosslin, Carol Haynes, Jennifer Dungan, et al. “Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events.” Circ Cardiovasc Genet 3, no. 2 (April 2010): 207–14. https://doi.org/10.1161/CIRCGENETICS.109.852814.
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  - Eagle, Kim A., Geoffrey S. Ginsburg, Kiran Musunuru, William C. Aird, Robert S. Balaban, Susan K. Bennett, Roger S. Blumenthal, et al. “Identifying patients at high risk of a cardiovascular event in the near future: current status and future directions: report of a national heart, lung, and blood institute working group.” Circulation 121, no. 12 (March 30, 2010): 1447–54. https://doi.org/10.1161/CIRCULATIONAHA.109.904029.
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  - Zaas, Aimee K., Hamza Aziz, Joseph Lucas, John R. Perfect, and Geoffrey S. Ginsburg. “Blood gene expression signatures predict invasive candidiasis.” Sci Transl Med 2, no. 21 (March 3, 2010): 21ra17. https://doi.org/10.1126/scitranslmed.3000715.
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  - Tsalik, Ephraim L., Edward F. Hendershot, Devdutta G. Sangvai, Hannah M. Cunningham, Coleen K. Cunningham, Maria G. Lopez-Marti, William K. Purdy, Christopher W. Woods, and L Brett Caram. “Clinical presentation and response to treatment of novel influenza A H1N1 in a university-based summer camp population.” J Clin Virol 47, no. 3 (March 2010): 286–88. https://doi.org/10.1016/j.jcv.2009.12.012.
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  - Zaas, A. K., M. Chen, A. O. Hero, J. Lucas, L. Carin, and G. S. Ginsburg. “Response: Improving Development of the Molecular Signature for Diagnosis of Acute Respiratory Viral Infections.” Cell Host and Microbe 7, no. 2 (February 18, 2010): 102. https://doi.org/10.1016/j.chom.2010.02.002.
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  - Kutty, Preeta K., Christopher W. Woods, Arlene C. Sena, Stephen R. Benoit, Susanna Naggie, Joyce Frederick, Sharon Evans, Jeffery Engel, and L Clifford McDonald. “Risk factors for and estimated incidence of community-associated Clostridium difficile infection, North Carolina, USA.” Emerg Infect Dis 16, no. 2 (February 2010): 197–204. https://doi.org/10.3201/eid1602.090953.
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  - Chiba-Falek, Ornit, Marshall Nichols, Sunil Suchindran, John Guyton, Geoffrey S. Ginsburg, Elizabeth Barrett-Connor, and Jeanette J. McCarthy. “Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study.” Bmc Medical Genetics 11 (January 19, 2010): 9. https://doi.org/10.1186/1471-2350-11-9.
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  - Ginsburg, G. S. “Translational Genomics: From Discovery to Clinical Practice,” December 1, 2009, 242–51. https://doi.org/10.1016/B978-0-12-369420-1.00022-6.
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  - Ginsburg, G. S., and H. F. Willard. “Genomic and Personalized Medicine, Two-Vol Set.” Genomic and Personalized Medicine, Two Vol Set, December 1, 2009.
  - Ginsburg, Geoffrey S., and Huntington F. Willard. “Genomic and personalized medicine: foundations and applications.” Transl Res 154, no. 6 (December 2009): 277–87. https://doi.org/10.1016/j.trsl.2009.09.005.
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  - Lendlein, A., V. P. Shastri, and K. Gall. “Preface.” Materials Research Society Symposium Proceedings 1190 (December 1, 2009).
  - Voora, D., and G. S. Ginsburg. “Pharmacogenetics of the response to statins.” Current Cardiovascular Risk Reports 3, no. 6 (December 1, 2009): 434–40. https://doi.org/10.1007/s12170-009-0064-1.
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  - Kawamoto, Kensaku, Lori A. Orlando, Deepak Voora, David F. Lobach, Scott Joy, Alex Cho, and Geoffrey S. Ginsburg. “Evaluation of the PharmGKB knowledge base as a resource for efficiently assessing the clinical validity and utility of pharmacogenetic assays.” Amia Annu Symp Proc 2009 (November 14, 2009): 307–11.
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  - Voora, Deepak, Svati H. Shah, Ivan Spasojevic, Shazia Ali, Carol R. Reed, Benjamin A. Salisbury, and Geoffrey S. Ginsburg. “The SLCO1B1*5 genetic variant is associated with statin-induced side effects.” J Am Coll Cardiol 54, no. 17 (October 20, 2009): 1609–16. https://doi.org/10.1016/j.jacc.2009.04.053.
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  - Zaas, Aimee K., Minhua Chen, Jay Varkey, Timothy Veldman, Alfred O. Hero, Joseph Lucas, Yongsheng Huang, et al. “Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans.” Cell Host Microbe 6, no. 3 (September 17, 2009): 207–17. https://doi.org/10.1016/j.chom.2009.07.006.
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  - Sinnaeve, Peter R., Mark P. Donahue, Peter Grass, David Seo, Jacky Vonderscher, Salah-Dine Chibout, William E. Kraus, et al. “Gene expression patterns in peripheral blood correlate with the extent of coronary artery disease.” Plos One 4, no. 9 (September 14, 2009): e7037. https://doi.org/10.1371/journal.pone.0007037.
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  - Khoury, Muin J., Colleen M. McBride, Sheri D. Schully, John P. A. Ioannidis, W Gregory Feero, A Cecile J. W. Janssens, Marta Gwinn, et al. “The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop.” Genet Med 11, no. 8 (August 2009): 559–67. https://doi.org/10.1097/GIM.0b013e3181b13a6c.
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  - Ginsburg, G. “Genomic and Personalized Medicine: Happening now.” Personalized Medicine 6, no. 1 (July 29, 2009): 15–18. https://doi.org/10.2217/17410541.6.1.15.
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  - Wingrove, James A., Michael Elashoff, Whittemore G. Tingley, Amy J. Sehnert, Susan E. Daniels, Steven Rosenberg, William E. Kraus, L. K. Newby, and Geoffrey S. Ginsburg. “Development and Validation of a Peripheral Blood-Based Gene Expression Algorithm for the Detection of Coronary Artery Disease (CAD).” Arteriosclerosis Thrombosis and Vascular Biology 29, no. 7 (July 1, 2009): E24–E24.
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  - Broadfoot, Marla Vacek, and Geoffrey S. Ginsburg. “The Center for Genomic Medicine at the Duke Institute for Genome Sciences & Policy: propelling genomics into clinical practice.” Per Med 6, no. 3 (May 2009): 255–61. https://doi.org/10.2217/pme.09.9.
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  - Kawamoto, Kensaku, David F. Lobach, Huntington F. Willard, and Geoffrey S. Ginsburg. “A national clinical decision support infrastructure to enable the widespread and consistent practice of genomic and personalized medicine.” Bmc Med Inform Decis Mak 9 (March 23, 2009): 17. https://doi.org/10.1186/1472-6947-9-17.
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  - Burt, T. P., and R. J. Allison. “Sediment Cascades: An Integrated Approach.” Sediment Cascades: An Integrated Approach, January 1, 2009, 1–471. https://doi.org/10.1002/9780470682876.
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  - Garman, K. S., C. R. Acharya, E. Edelman, M. Grade, J. Gaedcke, S. Sud, W. Barry, et al. “Erratum: A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities (Proceedings of the National Academy of Sciences of the United States of America (2008) 105:49 (19432-19437) Doi: 10.1073/pnas.0806674105).” Proceedings of the National Academy of Sciences of the United States of America 106, no. 16 (2009): 6878-. https://doi.org/10.1073/pnas.0902004106.
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  - Ginsburg, Geoffrey S., and Jeanette J McCarthy. “Transforming the practice of medicine using genomics.” Clin Cases Miner Bone Metab 6, no. 1 (January 2009): 25–28.
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  - Willard, H. F., and G. S. Ginsburg. “Preface.” Genomic and Personalized Medicine, Two Vol Set, January 1, 2009. https://doi.org/10.1016/b978-0-12-369420-1.00114-1.
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  - Shah, Svati H., Elizabeth R. Hauser, James R. Bain, Michael J. Muehlbauer, Carol Haynes, Robert D. Stevens, Brett R. Wenner, et al. “High heritability of metabolomic profiles in families burdened with premature cardiovascular disease.” Mol Syst Biol 5 (2009): 258. https://doi.org/10.1038/msb.2009.11.
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  - Shah, Svati H., Neil J. Freedman, Lisheng Zhang, David R. Crosslin, David H. Stone, Carol Haynes, Jessica Johnson, et al. “Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis.” Plos Genet 5, no. 1 (January 2009): e1000318. https://doi.org/10.1371/journal.pgen.1000318.
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  - Garman, Katherine S., Chaitanya R. Acharya, Elena Edelman, Marian Grade, Jochen Gaedcke, Shivani Sud, William Barry, et al. “A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities.” Proc Natl Acad Sci U S A 105, no. 49 (December 9, 2008): 19432–37. https://doi.org/10.1073/pnas.0806674105.
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  - Voora, Deepak, Svati H. Shah, Carol R. Reed, Jun Zhai, David R. Crosslin, Chad Messer, Benjamin A. Salisbury, and Geoffrey S. Ginsburg. “Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response.” Circ Cardiovasc Genet 1, no. 2 (December 2008): 100–106. https://doi.org/10.1161/CIRCGENETICS.108.795013.
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  - Califf, Robert M., and Geoffrey S. Ginsburg. “Organizational improvements to enhance modern clinical epidemiology.” Jama 300, no. 19 (November 19, 2008): 2300–2302. https://doi.org/10.1001/jama.2008.638.
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  - Voora, Deepak, Shazia Ali, Svati H. Shah, Carol R. Reed, Benjamin Salisbury, and Geoffrey S. Ginsburg. “Association of Statin-Induced Musculoskeletal Side Effects with Sex and a Hepatic Uptake Transporter Reduced Function Allele, SLC01B1*5.” Circulation 118, no. 18 (October 28, 2008): S326–S326.
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  - Wingrove, James A., Michael Elashoff, Whittemore G. Tingley, Amy J. Sehnert, Susan E. Daniels, Nicholas F. Paoni, Steven Rosenberg, William E. Kraus, L. K. Newby, and Geoffrey S. Ginsburg. “Discovery of Genes Expressed in Whole Blood which Identity Patients with Coronary Artery Disease.” Circulation 118, no. 18 (October 28, 2008): S389–S389.
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  - Wingrove, James A., Susan E. Daniels, Amy J. Sehnert, Whittemore Tingley, Michael R. Elashoff, Steven Rosenberg, Lutz Buellesfeld, et al. “Correlation of peripheral-blood gene expression with the extent of coronary artery stenosis.” Circ Cardiovasc Genet 1, no. 1 (October 2008): 31–38. https://doi.org/10.1161/CIRCGENETICS.108.782730.
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  - Ginsburg, Geoffrey S. “Genomic Medicine: 'grand challenges' in the translation of genomics to human health.” Eur J Hum Genet 16, no. 8 (August 2008): 873–74. https://doi.org/10.1038/ejhg.2008.115.
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  - Glickman, Seth W., Kevin J. Anstrom, Li Lin, Abhinav Chandra, Daniel T. Laskowitz, Christopher W. Woods, Debra H. Freeman, et al. “Challenges in enrollment of minority, pediatric, and geriatric patients in emergency and acute care clinical research.” Ann Emerg Med 51, no. 6 (June 2008): 775-780.e3. https://doi.org/10.1016/j.annemergmed.2007.11.002.
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  - Acharya, Chaitanya R., David S. Hsu, Carey K. Anders, Ariel Anguiano, Kelly H. Salter, Kelli S. Walters, Richard C. Redman, et al. “Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer.” Jama 299, no. 13 (April 2, 2008): 1574–87. https://doi.org/10.1001/jama.299.13.1574.
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  - Meadows, Sarah K., Holly K. Dressman, Garrett G. Muramoto, Heather Himburg, Alice Salter, ZhengZheng Wei, Geoffrey S. Ginsburg, Nelson J. Chao, Joseph R. Nevins, and John P. Chute. “Gene expression signatures of radiation response are specific, durable and accurate in mice and humans.” Plos One 3, no. 4 (April 2, 2008): e1912. https://doi.org/10.1371/journal.pone.0001912.
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  - Ginsburg, Geoffrey S., Thomas W. Burke, and Phillip Febbo. “Centralized biorepositories for genetic and genomic research.” Jama 299, no. 11 (March 19, 2008): 1359–61. https://doi.org/10.1001/jama.299.11.1359.
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  - Douglas, Pamela S., and Geoffrey S. Ginsburg. “Clinical genomic testing: getting it right.” J Cardiovasc Transl Res 1, no. 1 (March 2008): 17–20. https://doi.org/10.1007/s12265-007-9004-y.
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  - DeMaria, Anthony N., Jeroen J. Bax, Ori Ben-Yehuda, Paul Clopton, Gregory K. Feld, Geoffrey S. Ginsburg, Barry H. Greenberg, et al. “Highlights of the year in JACC 2007.” J Am Coll Cardiol 51, no. 4 (January 29, 2008): 490–512. https://doi.org/10.1016/j.jacc.2007.12.003.
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  - Ginsburg, Geoffrey S. “Regression of atherosclerosis with therapeutic antibodies pipe cleaner or pipe dream?” J Am Coll Cardiol 50, no. 24 (December 11, 2007): 2319–21. https://doi.org/10.1016/j.jacc.2007.08.039.
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  - Lugogo, Njira L., Geoffrey S. Ginsburg, and Loretta G. Que. “Genetic profiling and tailored therapy in asthma: are we there yet?” Curr Opin Mol Ther 9, no. 6 (December 2007): 528–37.
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  - Potti, A., H. K. Dressman, A. Bild, R. F. Riedel, G. Chan, R. Sayer, J. Cragun, et al. “Corrigenda: Genomic signatures to guide the use of chemotherapeutics.” Nature Medicine 13, no. 11 (November 2007): 1388.
  - Shadick, N. A., J. E. Heller, M. E. Weinblatt, N. E. Maher, J. Cui, G. Ginsburg, J. Coblyn, et al. “Opposing effects of the D70 mutation and the shared epitope in HLA-DR4 on disease activity and certain disease phenotypes in rheumatoid arthritis.” Annals of the Rheumatic Diseases 66, no. 11 (November 2007): 1497–1502. https://doi.org/10.1136/ard.2006.067603.
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  - Voora, Deepalk, Carol R. Reed, Jun Zhai, Benjamin A. Salisbury, Svatj H. Shah, and Geoffrey S. Ginsburg. “Polymorphisms in ABCA1 predict statin mediated LDL cholesterol lowering and suggest an interaction with CETP.” Circulation 116, no. 16 (October 16, 2007): 178–178.
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  - Ginsburg, Geoffrey S., Svati H. Shah, and Jeanette J. McCarthy. “Taking cardiovascular genetic association studies to the next level.” J Am Coll Cardiol 50, no. 10 (September 4, 2007): 930–32. https://doi.org/10.1016/j.jacc.2007.05.025.
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  - Parker, Alex, Elena S. Izmailova, Jigna Narang, Sunita Badola, Tinh Le, Ronenn Roubenoff, Geoffrey S. Ginsburg, et al. “Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate.” J Rheumatol 34, no. 9 (September 2007): 1817–22.
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  - Dressman, Holly K., Garrett G. Muramoto, Nelson J. Chao, Sarah Meadows, Dawn Marshall, Geoffrey S. Ginsburg, Joseph R. Nevins, and John P. Chute. “Gene expression signatures that predict radiation exposure in mice and humans.” Plos Med 4, no. 4 (April 2007): e106. https://doi.org/10.1371/journal.pmed.0040106.
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  - Luo, Albert K., Brian K. Jefferson, Mario J. Garcia, Geoffrey S. Ginsburg, and Eric J. Topol. “Challenges in the phenotypic characterisation of patients in genetic studies of coronary artery disease.” J Med Genet 44, no. 3 (March 2007): 161–65. https://doi.org/10.1136/jmg.2006.045732.
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  - DeMaria, Anthony N., Ori Ben-Yehuda, Gregory K. Feld, Geoffrey S. Ginsburg, Barry H. Greenberg, Wilbur Y. W. Lew, Joao A. C. Lima, et al. “Highlights of the Year in JACC 2006.” J Am Coll Cardiol 49, no. 4 (January 30, 2007): 509–27. https://doi.org/10.1016/j.jacc.2006.12.008.
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  - Aziz, Hamza, Aimee Zaas, and Geoffrey S. Ginsburg. “Peripheral blood gene expression profiling for cardiovascular disease assessment.” Genomic Med 1, no. 3–4 (2007): 105–12. https://doi.org/10.1007/s11568-008-9017-x.
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  - Ginsburg, G. S. “Erratum: Genomics and medicine at a crossroads in chernobyl (Science (62)).” Science 314, no. 5806 (December 15, 2006): 1683.
  - Ginsburg, Geoffrey S., David Seo, and Camille Frazier. “Microarrays coming of age in cardiovascular medicine: standards, predictions, and biology.” J Am Coll Cardiol 48, no. 8 (October 17, 2006): 1618–20. https://doi.org/10.1016/j.jacc.2006.07.025.
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  - Ginsburg, Geoffrey S., Misha Angrist, and Robert Cook-Deegan. “Public health. Genomics and medicine at a crossroads in Chernobyl.” Science 314, no. 5796 (October 6, 2006): 62–63. https://doi.org/10.1126/science.1130274.
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  - Freedman, Neil J., and Geoffrey S. Ginsburg. “Novel--and "neu"--therapeutic possibilities for heart failure.” J Am Coll Cardiol 48, no. 7 (October 3, 2006): 1448–50. https://doi.org/10.1016/j.jacc.2006.07.005.
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  - Stallings, Sarah C., Dan Huse, Stan N. Finkelstein, William H. Crown, Whitney P. Witt, Jon Maguire, Arthur J. Hiller, Anthony J. Sinskey, and Geoffrey S. Ginsburg. “A framework to evaluate the economic impact of pharmacogenomics.” Pharmacogenomics 7, no. 6 (September 2006): 853–62. https://doi.org/10.2217/14622416.7.6.853.
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  - Potti, Anil, Sayan Mukherjee, Rebecca Petersen, Holly K. Dressman, Andrea Bild, Jason Koontz, Robert Kratzke, et al. “A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer.” N Engl J Med 355, no. 6 (August 10, 2006): 570–80. https://doi.org/10.1056/NEJMoa060467.
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  - Seo, David, Geoffrey S. Ginsburg, and Pascal J. Goldschmidt-Clermont. “Gene expression analysis of cardiovascular diseases: novel insights into biology and clinical applications.” J Am Coll Cardiol 48, no. 2 (July 18, 2006): 227–35. https://doi.org/10.1016/j.jacc.2006.02.070.
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  - Haga, Susanne B., and Geoffrey S. Ginsburg. “Prescribing BiDil: is it black and white?” J Am Coll Cardiol 48, no. 1 (July 4, 2006): 12–14. https://doi.org/10.1016/j.jacc.2006.04.017.
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  - Brooks, Richard, Christopher W. Woods, Daniel K. Benjamin, and Nancy E. Rosenstein. “Increased case-fatality rate associated with outbreaks of Neisseria meningitidis infection, compared with sporadic meningococcal disease, in the United States, 1994-2002.” Clin Infect Dis 43, no. 1 (July 1, 2006): 49–54. https://doi.org/10.1086/504804.
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  - Cotten, C Michael, Geoffrey S. Ginsburg, Ronald N. Goldberg, and Marcy C. Speer. “Genomic analyses: a neonatology perspective.” J Pediatr 148, no. 6 (June 2006): 720–26. https://doi.org/10.1016/j.jpeds.2006.01.006.
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  - Lalani, T., Z. A. Kanafani, V. H. Chu, L. Moore, G. R. Corey, P. Pappas, C. W. Woods, et al. “Prosthetic valve endocarditis due to coagulase-negative staphylococci: findings from the International Collaboration on Endocarditis Merged Database.” Eur J Clin Microbiol Infect Dis 25, no. 6 (June 2006): 365–68. https://doi.org/10.1007/s10096-006-0141-z.
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  - Ginsburg, Geoffrey S., and Misha Angrist. “The future may be closer than you think: a response from the Personalized Medicine Coalition to the Royal Society's report on personalized medicine.” Per Med 3, no. 2 (May 2006): 119–23. https://doi.org/10.2217/17410541.3.2.119.
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  - Pien, Brian C., J Royden Saah, Sara E. Miller, and Christopher W. Woods. “Use of sentinel laboratories by clinicians to evaluate potential bioterrorism and emerging infections.” Clin Infect Dis 42, no. 9 (May 1, 2006): 1311–24. https://doi.org/10.1086/503260.
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  - West, Mike, Geoffrey S. Ginsburg, Andrew T. Huang, and Joseph R. Nevins. “Embracing the complexity of genomic data for personalized medicine.” Genome Res 16, no. 5 (May 2006): 559–66. https://doi.org/10.1101/gr.3851306.
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  - Ginsburg, Geoffrey S., and Susanne B. Haga. “Translating genomic biomarkers into clinically useful diagnostics.” Expert Rev Mol Diagn 6, no. 2 (March 2006): 179–91. https://doi.org/10.1586/14737159.6.2.179.
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  - Demaria, Anthony N., Ori Ben-Yehuda, Daniel Berman, Gregory K. Feld, Jeffrey Ginsberg, Barry H. Greenberg, Wilbur Y. W. Lew, David Sahn, and Sotirios Tsimikas. “Highlights of the Year in JACC 2005.” J Am Coll Cardiol 47, no. 1 (January 3, 2006): 184–202. https://doi.org/10.1016/j.jacc.2005.11.020.
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  - Ginsburg, Geoffrey S., Richard P. Konstance, Jennifer S. Allsbrook, and Kevin A. Schulman. “Implications of pharmacogenomics for drug development and clinical practice.” Arch Intern Med 165, no. 20 (November 14, 2005): 2331–36. https://doi.org/10.1001/archinte.165.20.2331.
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  - Ginsburg, Geoffrey S., Mark P. Donahue, and L Kristin Newby. “Prospects for personalized cardiovascular medicine: the impact of genomics.” J Am Coll Cardiol 46, no. 9 (November 1, 2005): 1615–27. https://doi.org/10.1016/j.jacc.2005.06.075.
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  - Willard, Huntington F., Misha Angrist, and Geoffrey S. Ginsburg. “Genomic medicine: genetic variation and its impact on the future of health care.” Philos Trans R Soc Lond B Biol Sci 360, no. 1460 (August 29, 2005): 1543–50. https://doi.org/10.1098/rstb.2005.1683.
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  - Seo, David, and Geoffrey S. Ginsburg. “Genomic medicine: bringing biomarkers to clinical medicine.” Curr Opin Chem Biol 9, no. 4 (August 2005): 381–86. https://doi.org/10.1016/j.cbpa.2005.06.009.
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  - Jefferson, Brian K., Jennifer H. Foster, Jeanette J. McCarthy, Geoffrey Ginsburg, Alex Parker, Kandice Kottke-Marchant, and Eric J. Topol. “Aspirin resistance and a single gene.” Am J Cardiol 95, no. 6 (March 15, 2005): 805–8. https://doi.org/10.1016/j.amjcard.2004.11.045.
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  - Abrahams, Edward, Geoffrey S. Ginsburg, and Mike Silver. “The Personalized Medicine Coalition: goals and strategies.” Am J Pharmacogenomics 5, no. 6 (2005): 345–55. https://doi.org/10.2165/00129785-200505060-00002.
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  - Ross, Jeffrey S., David P. Schenkein, Robert Pietrusko, Mark Rolfe, Gerald P. Linette, James Stec, Nancy E. Stagliano, et al. “Targeted therapies for cancer 2004.” Am J Clin Pathol 122, no. 4 (October 2004): 598–609. https://doi.org/10.1309/5CWP-U41A-FR1V-YM3F.
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  - Ivanov, Gleb S., Jessie M. Kater, Shivkumar H. Jha, Erica A. Stutius, Ravleen Sabharwal, Marisa D. Tricarico, Geoffrey S. Ginsburg, and Josef S. Ozer. “Sp and GATA factors are critical for Apolipoprotein AI downstream enhancer activity in human HepG2 cells.” Gene 323 (December 24, 2003): 31–42. https://doi.org/10.1016/j.gene.2003.08.014.
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  - Ross, Jeffrey S., and Geoffrey S. Ginsburg. “The integration of molecular diagnostics with therapeutics. Implications for drug development and pathology practice.” Am J Clin Pathol 119, no. 1 (January 2003): 26–36. https://doi.org/10.1309/VMLL-66Y5-KHQ3-5KUE.
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  - Loscalzo, Joseph, Robert Balaban, Lance B. Becker, Geoffrey S. Ginsburg, Vladimir C. Hachinski, John E. Hall, Donald D. Heistad, et al. “Task Force on Strategic Research Direction: Basic Science Subgroup key science topics report.” Circulation 106, no. 20 (November 12, 2002): e149–61. https://doi.org/10.1161/01.cir.0000040842.08331.4e.
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  - Ross, Jeffrey S., and Geoffrey S. Ginsburg. “Integration of molecular diagnostics with therapeutics: implications for drug discovery and patient care.” Expert Rev Mol Diagn 2, no. 6 (November 2002): 531–41. https://doi.org/10.1586/14737159.2.6.531.
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  - Ross, Jeffrey S., and Geoffrey S. Ginsburg. “Integrating diagnostics and therapeutics: revolutionizing drug discovery and patient care.” Drug Discov Today 7, no. 16 (August 15, 2002): 859–64. https://doi.org/10.1016/s1359-6446(02)02405-4.
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  - Meyer, Joanne M., and Geoffrey S. Ginsburg. “The path to personalized medicine.” Curr Opin Chem Biol 6, no. 4 (August 2002): 434–38. https://doi.org/10.1016/s1367-5931(02)00340-x.
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  - Ginsburg, G. S., and J. J. McCarthy. “Personalized medicine: revolutionizing drug discovery and patient care.” Trends Biotechnol 19, no. 12 (December 2001): 491–96. https://doi.org/10.1016/s0167-7799(01)01814-5.
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  - Ross, J. S., N. E. Stagliano, M. J. Donovan, R. E. Breitbart, and G. S. Ginsburg. “Atherosclerosis: a cancer of the blood vessels?” Am J Clin Pathol 116 Suppl (December 2001): S97-107. https://doi.org/10.1309/YNCK-9R19-5JA3-K2K9.
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  - Ross, J. S., N. E. Stagliano, M. J. Donovan, R. E. Breitbart, and G. S. Ginsburg. “Atherosclerosis and cancer: common molecular pathways of disease development and progression.” Ann N Y Acad Sci 947 (December 2001): 271–92.
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  - Ginsburg, G. S., M. O’Toole, E. Rimm, P. S. Douglas, and N. Rifai. “Gender differences in exercise-induced changes in sex hormone levels and lipid peroxidation in athletes participating in the Hawaii Ironman triathlon. Ginsburg-gender and exercise-induced lipid peroxidation.” Clin Chim Acta 305, no. 1–2 (March 2001): 131–39. https://doi.org/10.1016/s0009-8981(00)00427-7.
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  - Yu, H. H., R. C. Pasternak, and G. S. Ginsburg. “Dyslipidemia in patients with CAD: Rational use of diets and drugs.” Consultant 40, no. 10 (September 1, 2000): 1762–72.
  - Ginsburg, G. S., and W. K. Silverman. “Gender role orientation and fearfulness in children with anxiety disorders.” J Anxiety Disord 14, no. 1 (January 2000): 57–67. https://doi.org/10.1016/s0887-6185(99)00033-x.
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  - Yu, H. H., R. C. Pasternak, and G. S. Ginsburg. “Lipid management for patients with CAD, Part 2: A guide to drug therapy.” Journal of Critical Illness 15, no. 6 (January 1, 2000): 302–15.
  - Yu, H. H., R. C. Pasternak, and G. S. Ginsburg. “Lipid management for patients with CAD, Part 1: What to expect, when to start. Consider an aggressive strategy for prevention of cardiac events.” Journal of Critical Illness 15, no. 5 (January 1, 2000): 247–64.
  - Yu, H. H., R. C. Pasternak, and G. S. Ginsburg. “Dyslipidemia in patients with CAD: How to make best use of drug therapy.” Consultant 40, no. 12 (January 1, 2000): 2097–2109.
  - Yu, H. H., G. S. Ginsburg, M. L. O’Toole, J. D. Otvos, P. S. Douglas, and N. Rifai. “Acute changes in serum lipids and lipoprotein subclasses in triathletes as assessed by proton nuclear magnetic resonance spectroscopy.” Arterioscler Thromb Vasc Biol 19, no. 8 (August 1999): 1945–49. https://doi.org/10.1161/01.atv.19.8.1945.
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  - Gauthier, B., M. Robb, F. Gaudet, G. S. Ginsburg, and R. McPherson. “Characterization of a cholesterol response element (CRE) in the promoter of the cholesteryl ester transfer protein gene: functional role of the transcription factors SREBP-1a, -2, and YY1.” J Lipid Res 40, no. 7 (July 1999): 1284–93.
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  - Rifai, N., P. S. Douglas, M. O’Toole, E. Rimm, and G. S. Ginsburg. “Cardiac troponin T and I, echocardiographic [correction of electrocardiographic] wall motion analyses, and ejection fractions in athletes participating in the Hawaii Ironman Triathlon.” Am J Cardiol 83, no. 7 (April 1, 1999): 1085–89. https://doi.org/10.1016/s0002-9149(99)00020-x.
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  - Satler, C. A., M. R. Vesely, P. Duggal, G. S. Ginsburg, and A. H. Beggs. “Multiple different missense mutations in the pore region of HERG in patients with long QT syndrome.” Hum Genet 102, no. 3 (March 1998): 265–72. https://doi.org/10.1007/s004390050690.
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  - Douglas, P. S., M. L. O’Toole, S. E. Katz, G. S. Ginsburg, W. D. Hiller, and R. H. Laird. “Left ventricular hypertrophy in athletes.” Am J Cardiol 80, no. 10 (November 15, 1997): 1384–88. https://doi.org/10.1016/s0002-9149(97)00693-0.
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  - Yu, H. H., G. S. Ginsburg, N. Harris, and N. Rifai. “Evaluation and clinical application of a direct low-density lipoprotein cholesterol assay in normolipidemic and hyperlipidemic adults.” Am J Cardiol 80, no. 10 (November 15, 1997): 1295–99. https://doi.org/10.1016/s0002-9149(97)00668-1.
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  - Joffe, I. I., M. F. Riley, S. E. Katz, G. S. Ginsburg, and P. S. Douglas. “Acquired dynamic left ventricular outflow tract obstruction complicating acute anterior myocardial infarction: serial echocardiographic and clinical evaluation.” J Am Soc Echocardiogr 10, no. 7 (September 1997): 717–21. https://doi.org/10.1016/s0894-7317(97)70114-7.
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  - Naganawa, S., H. N. Ginsberg, R. M. Glickman, and G. S. Ginsburg. “Intestinal transcription and synthesis of apolipoprotein AI is regulated by five natural polymorphisms upstream of the apolipoprotein CIII gene.” J Clin Invest 99, no. 8 (April 15, 1997): 1958–65. https://doi.org/10.1172/JCI119363.
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  - Satler, C. A., E. P. Walsh, M. R. Vesely, M. H. Plummer, G. S. Ginsburg, and H. J. Jacob. “Novel missense mutation in the cyclic nucleotide-binding domain of HERG causes long QT syndrome.” American Journal of Medical Genetics 65, no. 1 (October 2, 1996): 27–35. https://doi.org/10.1002/(SICI)1096-8628(19961002)65:1<27::AID-AJMG4>3.0.CO;2-V.
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  - Satler, C. A., E. P. Walsh, M. R. Vesely, M. H. Plummer, G. S. Ginsburg, and H. J. Jacob. “Novel missense mutation in the cyclic nucleotide-binding domain of HERG causes long QT syndrome.” Am J Med Genet 65, no. 1 (October 2, 1996): 27–35. https://doi.org/10.1002/(SICI)1096-8628(19961002)65:1<27::AID-AJMG4>3.0.CO;2-V.
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  - Auerbach, I., P. Chouraqui, and M. Motro. “Chest pain in women.” N Engl J Med 335, no. 11 (September 12, 1996): 820. https://doi.org/10.1056/NEJM199609123351113.
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  - Ginsburg, G. S., and P. S. Douglas. “Why cardiologists should be interested in estrogen.” Am J Cardiol 78, no. 5 (September 1, 1996): 559–61. https://doi.org/10.1016/s0002-9149(96)00365-7.
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  - Harris, N., E. J. Neufeld, J. W. Newburger, B. Ticho, A. Baker, G. S. Ginsburg, E. Rimm, and N. Rifai. “Analytical performance and clinical utility of a direct LDL-cholesterol assay in a hyperlipidemic pediatric population.” Clin Chem 42, no. 8 Pt 1 (August 1996): 1182–88.
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  - Ginsburg, G. S., A. Agil, M. O’Toole, E. Rimm, P. S. Douglas, and N. Rifai. “Effects of a single bout of ultraendurance exercise on lipid levels and susceptibility of lipids to peroxidation in triathletes.” Jama 276, no. 3 (July 17, 1996): 221–25.
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  - Douglas, P. S., and G. S. Ginsburg. “The evaluation of chest pain in women.” N Engl J Med 334, no. 20 (May 16, 1996): 1311–15. https://doi.org/10.1056/NEJM199605163342007.
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  - Harris, N., E. J. Neufeld, J. W. Newburger, B. Ticho, A. Baker, G. S. Ginsburg, E. Rimm, and N. Rifai. “Analytical performance and clinical utility of a direct LDL-cholesterol assay in a hyperlipidemic pediatric population.” Clinical Chemistry 42, no. 8 (January 1, 1996): 1182–88. https://doi.org/10.1093/clinchem/42.8.1182.
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  - Gaudet, F., and G. S. Ginsburg. “Transcriptional regulation of the cholesteryl ester transfer protein gene by the orphan nuclear hormone receptor apolipoprotein AI regulatory protein-1.” J Biol Chem 270, no. 50 (December 15, 1995): 29916–22. https://doi.org/10.1074/jbc.270.50.29916.
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  - Ginsburg, G. S., J. Ozer, and S. K. Karathanasis. “Intestinal apolipoprotein AI gene transcription is regulated by multiple distinct DNA elements and is synergistically activated by the orphan nuclear receptor, hepatocyte nuclear factor 4.” J Clin Invest 96, no. 1 (July 1995): 528–38. https://doi.org/10.1172/JCI118065.
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  - Leidig, G. A., R. C. Pasternak, G. Horowitz, and G. S. Ginsburg. “Effects of heparin and cardiac catheterization on serum lipoprotein and triglyceride levels.” Am J Cardiol 74, no. 1 (July 1, 1994): 47–52. https://doi.org/10.1016/0002-9149(94)90490-1.
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  - Oettgen, P., G. S. Ginsburg, G. L. Horowitz, and R. C. Pasternak. “Frequency of hypothyroidism in adults with serum total cholesterol levels > 200 mg/dl.” Am J Cardiol 73, no. 13 (May 15, 1994): 955–57. https://doi.org/10.1016/0002-9149(94)90138-4.
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  - Silverman, D. I., G. S. Ginsburg, and R. C. Pasternak. “High-density lipoprotein subfractions.” Am J Med 94, no. 6 (June 1993): 636–45. https://doi.org/10.1016/0002-9343(93)90217-d.
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  - Mietus-Snyder, M., F. M. Sladek, G. S. Ginsburg, C. F. Kuo, J. A. Ladias, J. E. Darnell, and S. K. Karathanasis. “Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells.” Mol Cell Biol 12, no. 4 (April 1992): 1708–18. https://doi.org/10.1128/mcb.12.4.1708-1718.1992.
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  - Ginsburg, G. S., and R. C. Pasternak. “Coronary artery disease risk when total cholesterol levels are desirable.” Cardiology Board Review 9, no. 5 (January 1, 1992): 83-84+89.
  - Ginsburg, G. S., C. Safran, and R. C. Pasternak. “Frequency of low serum high-density lipoprotein cholesterol levels in hospitalized patients with "desirable" total cholesterol levels.” Am J Cardiol 68, no. 2 (July 15, 1991): 187–92. https://doi.org/10.1016/0002-9149(91)90742-4.
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  - Ginsburg, G. S., M. T. Walsh, D. M. Small, and D. Atkinson. “Reassembled plasma low density lipoproteins. Phospholipid-cholesterol ester-apoprotein B complexes.” J Biol Chem 259, no. 10 (May 25, 1984): 6667–73.
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  - Ginsburg, G. S., D. Atkinson, and D. M. Small. “Physical properties of cholesteryl esters.” Prog Lipid Res 23, no. 3 (1984): 135–67. https://doi.org/10.1016/0163-7827(84)90002-x.
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  - Ginsburg, G. S., D. M. Small, and J. A. Hamilton. “Temperature-dependent molecular motions of cholesterol esters: a carbon-13 nuclear magnetic resonance study.” Biochemistry 21, no. 26 (December 21, 1982): 6857–67. https://doi.org/10.1021/bi00269a036.
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  - Ginsburg, G. S., D. M. Small, and D. Atkinson. “Microemulsions of phospholipids and cholesterol esters. Protein-free models of low density lipoprotein.” J Biol Chem 257, no. 14 (July 25, 1982): 8216–27.
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  - Ginsburg, G. S., and D. M. Small. “Physical properties of cholesteryl esters having 20 carbons or more.” Biochim Biophys Acta 664, no. 1 (April 23, 1981): 98–107. https://doi.org/10.1016/0005-2760(81)90032-1.
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  - Fry, A. J., and G. S. Ginsburg. “Stereoelectronic Control in the Electrochemical and Mercury-Promoted Reductive Acetoxylation of α,α’-Dibromobicycloalkanones.” Journal of the American Chemical Society 101, no. 14 (July 1, 1979): 3927–32. https://doi.org/10.1021/ja00508a034.
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  - Fry, A. J., and G. S. Ginsburg. “Additions and Corrections: Stereoelectronic Control in the Electrochemical and Mercury-Promoted Reductive Acetoxylation of α,α⎹-Dibromobicycloalkanones (Journal of the American Chemical Society (1979) 101(24) (7439)).” Journal of the American Chemical Society 101, no. 24 (February 1, 1979): 7439. https://doi.org/10.1021/ja00518a610.
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  - Fry, A. J., W. A. Donaldson, and G. S. Ginsburg. “Reductive Acetoxylation on α, α's-Dibromocycloalkanones by Ultrasonically Dispersed Mercury.” Journal of Organic Chemistry 44, no. 3 (January 1, 1979): 349–52. https://doi.org/10.1021/jo01317a008.
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  - Fry, A. J., G. S. Ginsburg, and R. A. Parente. “Reduction of α,α′-dibromoketones by ultrasonically dispersed mercury in some aliphatic ketone solvents. A convenient synthesis of 4-isopropylidene-1,3-dioxolans.” Journal of the Chemical Society, Chemical Communications, no. 23 (January 1, 1978): 1040–41. https://doi.org/10.1039/C39780001040.
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  - Bylstra, Yasmin, Weng Khong Lim, Sylvia Kam, Koei Wan Tham, R Ryanne Wu, Jing Xian Teo, Sonia Davila, et al. “Family History Assessment Significantly Enhances Delivery of Precision Medicine in the Genomics Era,” n.d. https://doi.org/10.1101/2020.01.29.926139.
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  - Haga, Susanne B., Ryan Shaw, Charles Kneifel, Sarah J. Bond, and Geoffrey S. Ginsburg. “Promoting Wellness Through Mobile Health Technology in a College Student Population: Protocol Development and Pilot Study (Preprint),” n.d. https://doi.org/10.2196/preprints.16474.
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  - Nimmagadda, Sai N., Firas S. Midani, Heather Durand, Aspen T. Reese, Caitlin C. Murdoch, Bradley P. Nicholson, Timothy Veldman, et al. “Nasal microbiota exhibit neither reproducible nor orderly dynamics following rhinoviral infection,” n.d. https://doi.org/10.1101/2020.04.11.20061911.
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- Book Sections
  - Woods, C. W., and E. L. Tsalik. “Overview: Genomic and precision medicine for infectious and inflammatory disease.” In Genomic and Precision Medicine: Infectious and Inflammatory Disease, 1–7, 2019. https://doi.org/10.1016/B978-0-12-801496-7.00001-0.
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  - Ginsburg, G. S., and S. B. Haga. “Foundations and application of precision medicine.” In Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics: Foundations, 21–45, 2018. https://doi.org/10.1016/B978-0-12-812537-3.00002-0.
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  - Ward, R., and G. S. Ginsburg. “Local and Global Challenges in the Clinical Implementation of Precision Medicine.” In Genomic and Precision Medicine: Foundations, Translation, and Implementation: Third Edition, 105–17, 2017. https://doi.org/10.1016/B978-0-12-800681-8.00007-4.
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  - Glurich, I., S. Shukla, A. Acharya, G. S. Ginsburg, and M. H. Brilliant. “The oral microbiome and its relationship to genomics and oral disease.” In Genomics, Personalized Medicine and Oral Disease, 35–65, 2015. https://doi.org/10.1007/978-3-319-17942-1_3.
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  - Orlando, L. A., and A. H. cho. “Clinical Implementation of Genomic Medicine in Primary Care.” In Genomic and Personalized Medicine, edited by G. S. ginsburg and H. willard. San Diego, CA: Academic Press, 2012.
- Other Articles
  - Kertai, Miklos D., Yen-Wei Li, Yi-Ju Li, Svati H. Shah, William E. Kraus, Manuel L. Fontes, Mark Stafford-Smith, et al. “G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockers.” Circ Cardiovasc Genet, October 2014. https://doi.org/10.1161/CIRCGENETICS.113.000451.
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  - Potti, A., H. K. Dressman, A. Bild, R. F. Riedel, G. Chan, R. Sayer, J. Cragun, et al. “Corrigendum: Genomic signatures to guide the use of chemotherapeutics (Nature Medicine (2006) 12, (1294-1300)).” Nature Medicine, August 1, 2008. https://doi.org/10.1038/nm0808-889.
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  - Potti, A., H. K. Dressman, A. Bild, R. F. Riedel, G. Chan, R. Sayer, J. Cragun, et al. “Erratum: Genomic signatures to guide the use of chemotherapeutics (Nature (2006) 12, (1294-1300)).” Nature Medicine, November 1, 2007. https://doi.org/10.1038/nm1107-1388.
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  - Dressman, Holly K., Andrew Berchuck, Gina Chan, Jun Zhai, Andrea Bild, Robyn Sayer, Janiel Cragun, et al. “An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer.” J Clin Oncol, February 10, 2007. https://doi.org/10.1200/JCO.2006.06.3743.
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  - Potti, Anil, Holly K. Dressman, Andrea Bild, Richard F. Riedel, Gina Chan, Robyn Sayer, Janiel Cragun, et al. “Genomic signatures to guide the use of chemotherapeutics.” Nature Medicine, November 2006. https://doi.org/10.1038/nm1491.
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- Conference Papers
  - Jr, Limkakeng A. T., I. Zhbannikov, P. S. Douglas, U. Hoffman, M. Ferencik, S. Shah, W. Kraus, L. Cooper, D. Voora, and G. S. Ginsburg. “Biomarker Profiling for Obstructive Coronary Artery Disease: A PROMISE Substudy.” In Annals of Emergency Medicine, 76:S116–S116, 2020.
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  - Zeitouni, Michel, Stephanie N. Giamberardino, Robert McGarrah, Neha Pagidipati, Geoffrey S. Ginsburg, Udo Hoffmann, Ann Marie Navar, Pamela Douglas, and Svati Shah. “A NOVEL INFLAMMATORY MARKER OF GLYCOSYLATED PROTEINS IS ASSOCIATED WITH CAD AND INCIDENT EVENTS AND DEMONSTRATES AGE EFFECTS IN THE PROMISE TRIAL.” In Journal of the American College of Cardiology, 75:263–263. ELSEVIER SCIENCE INC, 2020.
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  - McGarrah, R. W., M. Ferencik, S. N. Giamberardino, A. Coles, U. Hoffmann, G. S. Ginsburg, W. E. Kraus, P. S. Douglas, and S. H. Shah. “Lipoprotein subclasses associated with high-risk coronary atherosclerotic plaque: insights from the PROMISE clinical trial.” In European Heart Journal, 40:51–51. OXFORD UNIV PRESS, 2019.
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  - Myers, Rachel A., Thomas L. Ortel, Alexander Waldrop, Sandeep Dave, Geoffrey S. Ginsburg, and Deepak Voora. “Aspirin Responsive Platelet Genes Are Associated With Platelet Function and Reflect a Non-Cyclooxygenase Mediated Effect.” In Circulation, Vol. 138, 2018.
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  - Myers, Rachel A., Thomas L. Ortel, Alexander Waldrop, Sandeep Dave, Geoffrey S. Ginsburg, and Deepak Voora. “Ticagrelor Responsive Platelet Genes Are Associated With Platelet Function and Bleeding.” In Circulation, Vol. 138, 2018.
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  - Meyersohn, N. M., T. Mayrhofer, A. Ivanov, D. O. Bittner, P. V. Staziaki, B. Szilveszter, T. Hallett, et al. “Association of hepatic steatosis with adverse cardiovascular events: insights from the PROspective Multicenter Imaging Study for Evaluation of chest pain (PROMISE) trial.” In European Heart Journal, 39:1286–1286. OXFORD UNIV PRESS, 2018.
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  - Orlando, Lori A., R. R. Wu, Adam Buchanan, Rachel A. Myers, and Geoffrey S. Ginsburg. “THE INTERSECTION OF POPULATION HEALTH AND PRECISION MEDICINE: EMPLOYING TECHNOLOGY TO OPTIMIZE RISK ASSESSMENT IN PRIMARY CARE.” In Journal of General Internal Medicine, 33:S362–S362. SPRINGER, 2018.
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  - Tillekeratne, L., Sunil Suchindran, Emily Ko, Elizabeth Petzold, Champica Bodinayake, Ajith Nagahawatte, Vasantha Devasiri, et al. “A GENE EXPRESSION SIGNATURE ACCURATELY IDENTIFIES VIRAL ACUTE RESPIRATORY INFECTIONS IN A SRI LANKAN POPULATION.” In American Journal of Tropical Medicine and Hygiene, 99:641–42. AMER SOC TROP MED & HYGIENE, 2018.
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  - Januzzi, James L., Sunil Suchindran, Adrian Coles, Maros Ferencik, Manesh R. Patel, Udo Hoffmann, Geoffrey S. Ginsburg, and Pamela S. Douglas. “High Sensitivity Troponin I Measurement in Symptomatic Outpatients With Suspected Coronary Artery Disease: Results From the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) Study,” 136:A16672–A16672. American Heart Association, Inc., 2017.
  - McGarrah, Robert W., Ann M. Navar, Stephanie Giamberardino, Adrian Coles, Lydia C. Kwee, Udo Hoffmann, Geoffrey S. Ginsburg, William E. Kraus, Pamela S. Douglas, and Svati H. Shah. “NMR Lipoprotein Profiling Identifies HDL Subclasses Associated With Obstructive CAD: Insights From the PROMISE Clinical Trial,” 136:A18001–A18001. American Heart Association, Inc., 2017.
  - Ngo, H. T., H. N. Wang, T. Burke, C. Woods, G. S. Ginsburg, and T. Vo-Dinh. “Multiplex DNA biosensor for viral infection diagnosis using SERS molecular sentinel-on-chip.” In Ifmbe Proceedings, 46:15–20, 2015. https://doi.org/10.1007/978-3-319-11776-8_4.
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  - Li, Josephine H., Sunil Suchindran, Svati H. Shah, William E. Kraus, Geoffrey S. Ginsburg, and Deepak Voora. “Effect of SLCO1B1*5 on Low-Density Lipoprotein Cholesterol Levels and Long-Term Clinical Events in Patients During Statin Therapy Following Cardiac Catheterization.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Cho, Alex, Allison Vorderstrasse, Sunil Suchindran, Joseph Lucas, William Michael Scott, Marylou Bembe, Dana Baker, et al. “T2D Genetic Risk Counseling & Testing in Primary Care.” In Diabetes, 62:A196–A196. AMER DIABETES ASSOC, 2013.
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  - Wu, Rebekah R., Tiffany Himmel, Adam Buchanan, Karen Powell, Elizabeth Hauser, Astrid B. Agbaje, Geoffrey S. Ginsburg, Vincent Henrich, and Lori A. Orlando. “IMPACT OF A FAMILY HISTORY COLLECTION TOOL, METREE (c), IN IDENTIFYING INDIVIDUALS AT HIGH-RISK FOR CANCER AND THROMBOSIS.” In Journal of General Internal Medicine, 28:S101–S101. SPRINGER, 2013.
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  - Wu, Rebekah R., Tiffany Himmel, Karen Powell, Elizabeth Hauser, Astrid B. Agbaje, Vincent Henrich, Geoffrey S. Ginsburg, and Lori A. Orlando. “USABILITY OF A FAMILY HEALTH HISTORY AND CLINICAL DECISION SUPPORT TOOL FOR PATIENTS AND PRIMARY CARE PROVIDERS.” In Journal of General Internal Medicine, 28:S233–S233. SPRINGER, 2013.
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  - Kraft, B., C. A. Piantadosi, H. B. Suliman, G. S. Ginsburg, R. R. Bartz, A. Zaas, M. Betancourt, and K. E. Welty-Wolf. “Pneumococcal Pneumonia And Sepsis In Baboons Mirrors The Human Disease.” In American Journal of Respiratory and Critical Care Medicine, Vol. 187. AMER THORACIC SOC, 2013.
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  - Tingley, Whittemore G., James A. Wingrove, Amy J. Sehnert, Michael Elashoff, Susan E. Daniels, Steven Rosenberg, Lutz Buellesfeld, et al. “Gene Expression in Peripheral Blood Reflects the Presence and Extent of Coronary Artery Stenosis.” In American Journal of Cardiology, 102:55I-55I. EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, 2008.
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  - Shah, Svati H., James Bain, Michael J. Muehlbauer, Robert D. Stevens, Brett R. Wenner, Lauren C. Naliboff, Carol Haynes, et al. “Peripheral blood metabolic signatures are markers of coronary artery disease and myocardial infarction.” In Circulation, Vol. 117. LIPPINCOTT WILLIAMS & WILKINS, 2008.
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  - Shah, Svati H., Christopher B. Newgard, James Bain, Robert Stevens, Brett Wenner, Michael Muehlbauer, Elaine Dowdy, et al. “High heritabilities of serum metabolites and differential metabolomic profiles in families burdened with early onset coronary artery disease.” In Circulation, 114:677–677. LIPPINCOTT WILLIAMS & WILKINS, 2006.
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  - Ginsburg, Geoffrey S., Julie Lekstrom-Himes, and William Trepicchio. “Optimizing biomarker development for clinical studies at the lead optimization stage of drug development.” In Optimizing the Drug Like Properties of Leads in Drug Discovery, edited by R. T. Borchardt, E. H. Kerns, M. J. Hageman, D. R. Thakker, and J. L. Stevens, 4:411-+. SPRINGER, 2006.
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Teaching & Mentoring
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- BME 493: Projects in Biomedical Engineering (GE) 2020
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