Diane Gesty-Palmer
Adjunct Assistant Professor in the Department of Medicine

Dr. Gesty-Palmer is an Assistant Professor in the Department of Medicine and Division of Endocrinology and Metabolism. Her laboratory principally examines G protein-coupled receptor signaling mechanisms in bone metabolism with emphasis on parathyroid hormone (PTH) receptor biased agonism. These studies explore novel mechanisms of PTH receptor signaling and the contributions of β-arrestin to modulate bone formation and bone resorption. Her work has recently shown that β-arrestin, classically thought to turn off G protein signaling, activates a distinct G protein-independent signaling mechanism to stimulate bone formation. Examination of β-arrestin mediated signaling events may provide novel therapeutic targets for the treatment of metabolic bone diseases such as osteoporosis. Dr. Gesty-Palmer is the recipient of a BIRCWH Scholar Award for Interdisciplinary Research in Women’s Health in 2006 and an Arthritis Foundation Investigator Award in 2007.

Current Appointments & Affiliations

Contact Information

  • Duke Box 103015, Durham, NC 27710
  • Medical Center Box 103015, Division Of Endocrinology, Durham, NC 27710

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.