Journal ArticleAm J Transplant · January 2026
Conventional immunosuppressive regimens in kidney transplantation continue to pose significant challenges, largely due to their reliance on calcineurin inhibitors (CNIs) and corticosteroids. These challenges have driven the search for alternative regimens ...
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Journal ArticleTranspl Immunol · December 2025
PURPOSE: Belatacept has been associated with less de novo specific antibody (dnDSA) development, but few publications have compared the incidence of dnDSA development between tacrolimus and belatacept-based immunosuppression regimens. The purpose of this s ...
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Journal ArticleTransplantation · September 1, 2025
Solid organ transplantation (SOT) offers people with end-stage organ disease an increased quality of life, which includes the return of fertility and the potential for pregnancy. Although the number of pregnancies has increased, definitive recommendations ...
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Journal ArticleClin Transplant · July 2025
Transplantation is one of the few life-saving therapies for patients with end-stage organ disease, yet organ availability remains restrictive. Expanding donors to include those with hepatitis B virus (HBV) infection, incorporating HBV nucleic acid amplific ...
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Journal ArticleTransplantation · March 13, 2025
Solid organ transplantation (SOT) offers people with end-stage organ disease an increased quality of life, which includes the return of fertility and the potential for pregnancy. Although the number of pregnancies has increased, definitive recommendations ...
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Journal ArticleCurr Opin Organ Transplant · February 1, 2025
PURPOSE OF REVIEW: This review summarizes the different instruments for evaluating the psychosocial health of transplant candidates, the evidence demonstrating how these instruments relate to probability of transplant waitlisting and transplant outcomes, a ...
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Journal ArticleClin J Am Soc Nephrol · December 13, 2024
KEY POINTS: Declines in referral mirror national trends; however, declines were less for some groups receiving the intervention, warranting long-term follow-up. The findings provide important context for future modification and scale-up of multilevel, mult ...
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Journal ArticleJ Pharm Pract · December 2024
Objectives: Tacrolimus remains the mainstay of immunosuppression in kidney transplantation. Understanding the relationship between therapeutic tacrolimus levels and outcomes of acute rejection, patient/graft survival, and tolerability are important. The re ...
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Journal ArticleClin J Am Soc Nephrol · December 1, 2024
Living kidney donation and living liver donation significantly increases organ supply to make lifesaving transplants possible, offering survival benefits to the recipients and cost savings to society. Of all living donors, 40% are women of childbearing age ...
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Journal ArticleTranspl Infect Dis · October 2024
BACKGROUND: In kidney transplantation, concerns have been raised regarding increased incidence of viral opportunistic infections in hepatitis C virus (HCV) nucleic acid test (NAT)-negative (-) recipients who received HCV NAT-positive (+) donor kidneys, spe ...
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Journal ArticleClin J Am Soc Nephrol · September 20, 2024
Living kidney donation and living liver donation significantly increases organ supply to make lifesaving transplants possible, offering survival benefits to the recipients and cost savings to society. Of all living donors, 40% are women of childbearing age ...
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Journal ArticleFront Transplant · 2024
Cytomegalovirus (CMV) infection poses a significant threat to solid organ transplant (SOT) recipients and can lead to various complications and adverse outcomes. In an effort to prevent CMV infection, it is common to utilize prophylactic strategies, includ ...
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Journal ArticleKidney Med · December 2023
RATIONALE & OBJECTIVE: Pregnancy in females with kidney disease is not uncommon and is associated with adverse maternal and fetal outcomes. The use of contraception in females with chronic kidney disease remains low. We sought to describe the perspectives ...
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Journal ArticleTransplant Proc · 2023
BACKGROUND: To evaluate the effect of the Affordable Care Act (ACA) Medicaid expansion on payor mix among patients on the kidney and liver transplant waiting list as well as waiting list and post-transplant outcomes. DESIGN: Using the Scientific Registry o ...
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Journal ArticleClin Transplant · December 2022
Sex and gender disparity exist in various stages of kidney transplantation. Females were found to be less likely to be referred for kidney transplant, complete pre-transplant evaluation, be placed on the waitlist, and receive a kidney transplant compared t ...
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Journal ArticleKidney360 · September 29, 2022
BACKGROUND: Acute kidney injury (AKI) is most commonly caused by tubular injury and is associated with a wide variety of critical illnesses. It is well known that urinary biomarkers can lead to the early identification of AKI. However, the ability of urina ...
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Journal ArticleSemin Nephrol · March 2022
Sex and gender often are used interchangeably, but are two distinct entities, with sex being the biological attribute and gender including the social, psychological, and cultural aspects of one's identity. Kidney transplantation has been proven to be the b ...
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Journal ArticleSci Rep · February 3, 2021
In obesity, adipose tissue derived inflammation is associated with unfavorable metabolic consequences. Uremic inflammation is prevalent and contributes to detrimental outcomes. However, the contribution of adipose tissue inflammation in uremia has not been ...
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Journal ArticleAm J Cancer Res · 2021
Post-transplant lymphoproliferative disorders (PTLD) are among the most serious complications after solid organ transplantation (SOT). Monomorphic diffuse large B-cell lymphoma (DLBCL) is the most common subtype of PTLD. Historically, outcomes of PTLD have ...
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Chapter · January 1, 2021
Infection-induced kidney diseases need to be promptly detected to offer timely treatment of infections. The mechanisms by which infections lead to chronic kidney disease (CKD) includes direct invasion or indirectly by immune-mediated pathways known as infe ...
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Chapter · January 1, 2021
Once patients reach end-stage renal disease (ESRD), they have two options for renal replacement therapy available – chronic dialysis or kidney transplantation. Kidney transplantation has been proven to be the preferred treatment for individuals with ESRD, ...
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