Overview
I am trying to focus my research efforts in two specific areas, the medical intensive care unit, and clinical lung cancer research. Within the intensive care unit I am specifically interested in clinical trials and outcome evaluation. My interest in lung cancer centers on the clinical and cost effectiveness of various diagnostic procedures.
In the intensive care unit I am specifically involved in clinical trials for the adult respiratory distress syndrome (ARDS). At the present time I am on the steering committee for the NIH ARDS clinical trial network. We are currently enrolling patients in clinical protocols studying the effects of ventilator strategies, as well as novel therapeutic agents in the outcome of ARDS. I am also interested in ICU outcome research including statistical modeling of ICU outcomes.
My interest in lung cancer research centers on evaluating the efficacy of diagnostic tests in the diagnosis of pulmonary malignancy. I have retrospectively and prospectively evaluated bronchoscopic procedures, comparing the sensitivity and specificity of various techniques as well as their cost-effectiveness. I am also currently analyzing the clinical utility and cost-effectiveness of positron emission tomography in the diagnosis of lung cancer.
Key words: clinical trials, medical intensive care, lung cancer diagnostic testing
In the intensive care unit I am specifically involved in clinical trials for the adult respiratory distress syndrome (ARDS). At the present time I am on the steering committee for the NIH ARDS clinical trial network. We are currently enrolling patients in clinical protocols studying the effects of ventilator strategies, as well as novel therapeutic agents in the outcome of ARDS. I am also interested in ICU outcome research including statistical modeling of ICU outcomes.
My interest in lung cancer research centers on evaluating the efficacy of diagnostic tests in the diagnosis of pulmonary malignancy. I have retrospectively and prospectively evaluated bronchoscopic procedures, comparing the sensitivity and specificity of various techniques as well as their cost-effectiveness. I am also currently analyzing the clinical utility and cost-effectiveness of positron emission tomography in the diagnosis of lung cancer.
Key words: clinical trials, medical intensive care, lung cancer diagnostic testing
Current Appointments & Affiliations
Professor of Medicine
·
2018 - Present
Medicine, Pulmonary, Allergy, and Critical Care Medicine,
Medicine
Recent Publications
Missing the mark: inaccuracy of administrative data in identification of hospitalized patients with pneumonia and results of a systematic clinical reclassification process on readmission rates
Journal Article Journal of Hospital Administration · November 20, 2017 Full text Open Access CiteFluid management with a simplified conservative protocol for the acute respiratory distress syndrome*.
Journal Article Crit Care Med · February 2015 OBJECTIVES: In the Fluid and Catheter Treatment Trial (FACTT) of the National Institutes of Health Acute Respiratory Distress Syndrome Network, a conservative fluid protocol (FACTT Conservative) resulted in a lower cumulative fluid balance and better outco ... Full text Link to item CiteBody temperature and mortality in patients with acute respiratory distress syndrome.
Journal Article Am J Crit Care · January 2015 BACKGROUND: Little is known about the relationship between body temperature and outcomes in patients with acute respiratory distress syndrome (ARDS). A better understanding of this relationship may provide evidence for fever suppression or warming interven ... Full text Link to item CiteRecent Grants
Interdisciplinary Training Program in Lung Disease
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2009 - 2021Early Rehabilitation in Critical Care-Supine Cycling and Functional Electrical Stimulation
Clinical TrialCollaborator · Awarded by American Thoracic Society · 2014 - 2015SAILS
ResearchCo Investigator · Awarded by National Institutes of Health · 2010 - 2014View All Grants
Education, Training & Certifications
University of California, Irvine ·
1989
M.D.