Overview
Diabetes Mellitus: Prevention strategies, predictors, treatment effects; kidney and other complications including cardiovascular outcomes. Utilization of EHR data to construct tools to improve the care of diabetes and comorbid conditions.
Current Appointments & Affiliations
Professor of Medicine
·
2021 - Present
Medicine, Endocrinology, Metabolism, and Nutrition,
Medicine
Member in the Duke Clinical Research Institute
·
2008 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Advancement of the implementation of evidence-based therapies for cardiovascular-kidney-metabolic conditions: A multi-stakeholder perspective.
Journal Article Am Heart J · August 2025 Cardiovascular disease remains the leading cause of mortality and healthcare expenditures in the United States. It is also a major contributor to premature mortality, years lived with disability, and rising healthcare costs around the world. Despite the av ... Full text Link to item CiteThe potential for improving cardio-renal outcomes in chronic kidney disease with the aldosterone synthase inhibitor vicadrostat (BI 690517): a rationale for the EASi-KIDNEY trial.
Journal Article Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · May 2025 Patients with chronic kidney disease (CKD) are at risk of progressive loss of kidney function, heart failure, and cardiovascular death despite current proven therapies, including renin-angiotensin system inhibitors (RASi), sodium glucose co-transporter-2 i ... Full text CiteEmpagliflozin lowers serum uric acid in chronic kidney disease: exploratory analyses from the EMPA-KIDNEY trial.
Journal Article Nephrol Dial Transplant · April 1, 2025 BACKGROUND: Hyperuricaemia and gout are common in chronic kidney disease (CKD). We aimed to assess the effects of sodium-glucose co-transporter-2 (SGLT2) inhibition on uric acid (urate) and gout in patients with CKD. METHODS: The EMPA-KIDNEY trial randomis ... Full text Link to item CiteRecent Grants
Endocrinology and Metabolism Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029EASi-KIDNEY: The Study of Heart and Kidney Protection with "BI 690517"
Clinical TrialPrincipal Investigator · Awarded by The Chancellor Masters and Scholars of the University of Oxford · 2023 - 2029Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) - Microbiome Collection
Clinical TrialPrincipal Investigator · Awarded by The George Washington University · 2012 - 2025View All Grants
Education, Training & Certifications
University of Virginia ·
1993
M.D.