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Gregory Allan Fleming

Professor of Pediatrics
Pediatrics, Cardiology
DUMC Box 3090, 7506 Hospital North, Durham, NC 27710

Overview


Clinical interests include pediatric and adult congenital interventional cardiac catheterization and treatment of infants and children with acquired and congenital heart disease and adults with congenital heart diseaseĀ 

Research interests include assessment and development of interventional therapies for congenital heart disease, and perioperative management of infants and children with congenital heart disease requiring surgery.

Current Duke Appointments & Affiliations


Professor of Pediatrics · 2022 - Present Pediatrics, Cardiology, Pediatrics

Recent Scholarly Works


Surgical Rescue of Right Ventricular Outflow Tract Stent Malposition With Tricuspid Valve Compromise.

Journal article World J Pediatr Congenit Heart Surg · July 2026 Transcatheter ballon dilation has emerged as a valuable strategy to treat residual or recurrent right ventricular outflow tract (RVOT) obstruction following valve-sparing repair of tetralogy of Fallot (TOF). When balloon dilation is unsuccessful, stent pla ... Full text Link to item Cite

Five-Year Outcomes for Patients With RVOT Dysfunction Treated With the SAPIEN 3 Transcatheter Heart Valve: A Pooled Analysis From the COMPASSION S3 Trial.

Journal article Circ Cardiovasc Interv · May 2026 BACKGROUND: The COMPASSION S3 trial (Congenital Multicenter Trial of Pulmonic Valve Dysfunction Studying the SAPIEN 3 Interventional Transcatheter Heart Valve) was designed to evaluate the safety and effectiveness of the SAPIEN 3 transcatheter heart valve ... Full text Link to item Cite

Routine Use of Ultrasound in the Identification and Management of Thrombosis Following Pediatric Cardiac Catheterization.

Journal article Catheter Cardiovasc Interv · December 2025 BACKGROUND: Vessel occlusion post-catheterization is a common complication, yet there is no standard for diagnosis and treatment. As a result, there is variability in identification and management of post-catheterization thrombosis. AIMS: We aimed to (1) d ... Full text Link to item Cite
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Recent Grants


Harmony PAS

Clinical TrialPrincipal Investigator · Awarded by Medtronic, Inc. · 2022 - 2031

COngenital Multicenter trial of Pulmonic vAlve dysfunction Studying the SAPIEN 3 interventIONal THV Post-Approval Study

Clinical TrialPrincipal Investigator · Awarded by Edwards Lifesciences Corporation · 2021 - 2027

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Education


University of South Carolina, Columbia · 2003 M.D.