Current Duke Appointments & Affiliations
Associate Professor in Orthopaedic Surgery
·
2024 - Present
Orthopaedic Surgery,
Clinical Science Departments
Associate Professor in Pathology
·
2024 - Present
Pathology,
Clinical Science Departments
Member of Duke Molecular Physiology Institute
·
2017 - Present
Duke Molecular Physiology Institute,
Institutes and Centers
Affiliate of the Duke Regeneration Center
·
2021 - Present
Duke Regeneration Center,
Basic Science Departments
Recent Scholarly Works
Neutralizing hepatic apolipoprotein E enhances aged bone fracture healing.
Journal article Bone Res · January 22, 2026 Advanced age impairs bone fracture healing; the underlying mechanism of this phenomenon remains unknown. We determined that apolipoprotein E (ApoE) increases with age and causes poor fracture healing. After deletion of hepatic ApoE expression (ΔApoE), 24-m ... Full text Link to item CiteVagus nerve stimulation rescues persistent pain following orthopedic surgery in adult mice.
Conference Pain · August 1, 2024 Postoperative pain is a major clinical problem imposing a significant burden on patients and society. In a survey 2 years after orthopedic surgery, 57% of patients reported persisting postoperative pain. However, only limited progress has been made in the ... Full text Link to item CiteOsteoimmunology of Fracture Healing.
Journal article Curr Osteoporos Rep · June 2024 PURPOSE OF REVIEW: The purpose of this review is to summarize what is known in the literature about the role inflammation plays during bone fracture healing. Bone fracture healing progresses through four distinct yet overlapping phases: formation of the he ... Full text Link to item CiteRecent Grants
Cell and Molecular Biology Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of General Medical Sciences · 2026 - 2031Rejuvenation of B cells to improve aged fracture healing
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2026 - 2028A novel target in aged fracture healing
ResearchPrincipal Investigator · Awarded by National Institute on Aging · 2023 - 2028View All Grants
Education
Western University (Canada) ·
2009
Ph.D.