Gurpreet Baht
Assistant Professor in Orthopaedic Surgery
Current Appointments & Affiliations
- Assistant Professor in Orthopaedic Surgery, Orthopaedic Surgery, Clinical Science Departments 2021
- Assistant Professor in Pathology, Pathology, Clinical Science Departments 2021
- Member of Duke Molecular Physiology Institute, Duke Molecular Physiology Institute, Duke Molecular Physiology Institute 2017
- Affiliate of the Duke Regeneration Center, Regeneration Next Initiative, Basic Science Departments 2021
Contact Information
- Background
-
Education, Training, & Certifications
- Ph.D., University of Western Ontario (Canada) 2009
-
Previous Appointments & Affiliations
- Assistant Professor in Orthopaedic Surgery, Orthopaedic Surgery, Clinical Science Departments 2016 - 2020
- Assistant Professor in Pathology, Pathology, Clinical Science Departments 2017 - 2020
- Recognition
-
In the News
- Research
-
Selected Grants
- Localization of adenosine to promote fracture healing awarded by National Institutes of Health 2022 - 2027
- Modulation of local adenosine signaling to attenuate fracture pain awarded by National Institutes of Health 2021 - 2026
- Extracellular Vesicle Analyses to Develop Aging and Resilience Biomarkers awarded by National Institutes of Health 2021 - 2025
- Assessing healthspan in aged mice after prolonged exposure to young circulation awarded by National Institutes of Health 2020 - 2023
- Neurovascular dysfunction in delirium superimposed on dementia awarded by National Institutes of Health 2017 - 2023
- Correction of Immune Response Improves Aged Fracture Healing awarded by National Institutes of Health 2020 - 2022
- Extracellular Vesicles and Their Role in Hallmarks of Aging awarded by National Institutes of Health 2018 - 2020
- Investigating the role of Apolipoprotein E in pseudarthrosis following spinal fusion surgery awarded by AOSpine International 2019 - 2020
- Publications & Artistic Works
-
Selected Publications
-
Academic Articles
-
Huang, Rong, Abhinav R. Balu, Kristin H. Molitoris, James P. White, Alexander G. Robling, Ugur M. Ayturk, and Gurpreet S. Baht. “The role of Meteorin-like in skeletal development and bone fracture healing.” J Orthop Res, January 25, 2022. https://doi.org/10.1002/jor.25286.Full Text Link to Item
-
Huang, Rong, Linda Vi, Xiaohua Zong, and Gurpreet S. Baht. “Maresin 1 resolves aged-associated macrophage inflammation to improve bone regeneration.” Faseb J 34, no. 10 (October 2020): 13521–32. https://doi.org/10.1096/fj.202001145R.Full Text Link to Item
-
Baht, Gurpreet S., Akshay Bareja, David E. Lee, Rajesh R. Rao, Rong Huang, Janet L. Huebner, David B. Bartlett, et al. “Author Correction: Meteorin-like facilitates skeletal muscle repair through a Stat3/IGF-1 mechanism.” Nat Metab 2, no. 8 (August 2020): 794. https://doi.org/10.1038/s42255-020-0257-y.Full Text Link to Item
-
Baht, Gurpreet S., Akshay Bareja, David E. Lee, Rajesh R. Rao, Rong Huang, Janet L. Huebner, David B. Bartlett, et al. “Meteorin-like facilitates skeletal muscle repair through a Stat3/IGF-1 mechanism.” Nat Metab 2, no. 3 (March 2020): 278–89. https://doi.org/10.1038/s42255-020-0184-y.Full Text Link to Item
-
Zeng, Yuze, Yu-Ru V. Shih, Gurpreet S. Baht, and Shyni Varghese. “In Vivo Sequestration of Innate Small Molecules to Promote Bone Healing.” Adv Mater 32, no. 8 (February 2020): e1906022. https://doi.org/10.1002/adma.201906022.Full Text Link to Item
-
Miller-Rhodes, Patrick, Cuicui Kong, Gurpreet S. Baht, Priyanka Saminathan, Ramona M. Rodriguiz, William C. Wetsel, Harris A. Gelbard, and Niccolò Terrando. “The broad spectrum mixed-lineage kinase 3 inhibitor URMC-099 prevents acute microgliosis and cognitive decline in a mouse model of perioperative neurocognitive disorders.” J Neuroinflammation 16, no. 1 (October 28, 2019): 193. https://doi.org/10.1186/s12974-019-1582-5.Full Text Link to Item
-
Huang, Rong, Xiaohua Zong, Puviindran Nadesan, Janet L. Huebner, Virginia B. Kraus, James P. White, Phillip J. White, and Gurpreet S. Baht. “Lowering circulating apolipoprotein E levels improves aged bone fracture healing.” Jci Insight 4, no. 18 (September 19, 2019). https://doi.org/10.1172/jci.insight.129144.Full Text Link to Item
-
Miller-Rhodes, Patrick, Cuicui Kong, Gurpreet Baht, Ramona Rodriguiz, William Wetsel, Harris Gelbard, and Niccolò Terrando. “The broad spectrum mixed-lineage kinase 3 inhibitor URMC-099 prevents acute microgliosis and cognitive decline in a mouse model of perioperative neurocognitive disorders,” February 2019. https://doi.org/10.1101/537472.Full Text
-
Vi, Linda, Gurpreet S. Baht, Erik J. Soderblom, Heather Whetstone, Qingxia Wei, Bridgette Furman, Vijitha Puviindran, et al. “Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice.” Nat Commun 9, no. 1 (December 5, 2018): 5191. https://doi.org/10.1038/s41467-018-07666-0.Full Text Open Access Copy Link to Item
-
Baht, Gurpreet S., Linda Vi, and Benjamin A. Alman. “The Role of the Immune Cells in Fracture Healing.” Curr Osteoporos Rep 16, no. 2 (April 2018): 138–45. https://doi.org/10.1007/s11914-018-0423-2.Full Text Link to Item
-
Xiong, Chao, Zhiquan Zhang, Gurpreet S. Baht, and Niccolo Terrando. “A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration.” J Vis Exp, no. 132 (February 27, 2018). https://doi.org/10.3791/56701.Full Text Link to Item
-
Baht, Gurpreet S., Puviindran Nadesan, David Silkstone, and Benjamin A. Alman. “Pharmacologically targeting beta-catenin for NF1 associated deficiencies in fracture repair.” Bone 98 (May 2017): 31–36. https://doi.org/10.1016/j.bone.2017.02.012.Full Text Link to Item
-
Ng, Adeline H., Gurpreet S. Baht, Benjamin A. Alman, and Marc D. Grynpas. “Bone Marrow Stress Decreases Osteogenic Progenitors.” Calcif Tissue Int 97, no. 5 (November 2015): 476–86. https://doi.org/10.1007/s00223-015-0032-3.Full Text Link to Item
-
Baht, Gurpreet S., David Silkstone, Linda Vi, Puviindran Nadesan, Yasha Amani, Heather Whetstone, Qingxia Wei, and Benjamin A. Alman. “Erratum: Exposure to a youthful circulation rejuvenates bone repair through modulation of β-catenin.” Nat Commun 6 (August 26, 2015): 7761. https://doi.org/10.1038/ncomms8761.Full Text Link to Item
-
Vi, Linda, Gurpreet S. Baht, Heather Whetstone, Adeline Ng, Qingxia Wei, Raymond Poon, Sivakami Mylvaganam, Marc Grynpas, and Benjamin A. Alman. “Macrophages promote osteoblastic differentiation in-vivo: implications in fracture repair and bone homeostasis.” J Bone Miner Res 30, no. 6 (June 2015): 1090–1102. https://doi.org/10.1002/jbmr.2422.Full Text Link to Item
-
Baht, Gurpreet S., David Silkstone, Linda Vi, Puviindran Nadesan, Yasha Amani, Heather Whetstone, Qingxia Wei, and Benjamin A. Alman. “Exposure to a youthful circulaton rejuvenates bone repair through modulation of β-catenin.” Nat Commun 6 (May 19, 2015): 7131. https://doi.org/10.1038/ncomms8131.Full Text Link to Item
-
Baht, Gurpreet S., David Silkstone, Puviindran Nadesan, Heather Whetstone, and Benjamin A. Alman. “Activation of hedgehog signaling during fracture repair enhances osteoblastic-dependent matrix formation.” J Orthop Res 32, no. 4 (April 2014): 581–86. https://doi.org/10.1002/jor.22562.Full Text Link to Item
-
Craft, April M., Nazish Ahmed, Jason S. Rockel, Gurpreet S. Baht, Benjamin A. Alman, Rita A. Kandel, Agamemnon E. Grigoriadis, and Gordon M. Keller. “Specification of chondrocytes and cartilage tissues from embryonic stem cells.” Development 140, no. 12 (June 2013): 2597–2610. https://doi.org/10.1242/dev.087890.Full Text Link to Item
-
Baht, Gurpreet S., Jason O’Young, Antonia Borovina, Hong Chen, Coralee E. Tye, Mikko Karttunen, Gilles A. Lajoie, Graeme K. Hunter, and Harvey A. Goldberg. “Phosphorylation of Ser136 is critical for potent bone sialoprotein-mediated nucleation of hydroxyapatite crystals.” Biochem J 428, no. 3 (May 27, 2010): 385–95. https://doi.org/10.1042/BJ20091864.Full Text Link to Item
-
Baht, Gurpreet S., Graeme K. Hunter, and Harvey A. Goldberg. “Bone sialoprotein-collagen interaction promotes hydroxyapatite nucleation.” Matrix Biol 27, no. 7 (September 2008): 600–608. https://doi.org/10.1016/j.matbio.2008.06.004.Full Text Link to Item
-
-
Book Sections
-
Alman, Benjamin, and Gurpreet Baht. “Parabiosis: Assessing the Effects of Circulating Cells and Factors on the Skeleton.,” 2230:105–13, 2021. https://doi.org/10.1007/978-1-0716-1028-2_7.Full Text Link to Item
-
-
Conference Papers
-
Huang, Rong, Linda Vi, Xiaohua Zong, and Gurpreet Baht. “Maresin 1 resolves macrophage inflammation to improve aged bone fracture healing.” In Journal of Bone and Mineral Research, 35:163–163, 2020.Link to Item
-
Zong, Xiaohua, Puviindran Nadesan, James White, Phillip White, and Gurpreet Baht. “The role of apolipoprotein E in fracture healing and osteoblast differentiation.” In Journal of Bone and Mineral Research, 33:9–9. WILEY, 2018.Link to Item
-
Nadesan, Puviindran, and Gurpreet Baht. “A Role for Apolipoprotein E in Fracture Healing.” In Journal of Bone and Mineral Research, 32:S125–26. WILEY, 2017.Link to Item
-
Ng, Adeline, Gurpreet Baht, Marc Grynpas, and Benjamin Alman. “Osteoblast depletion increases osteoblast activity and reduces bone toughness in mice.” In Journal of Bone and Mineral Research, 29:S346–S346. WILEY-BLACKWELL, 2014.Link to Item
-
Baht, Gurpreet, and Benjamin Alman. “Rejuvenating Bone Fracture Repair.” In Journal of Bone and Mineral Research, Vol. 28. WILEY-BLACKWELL, 2013.Link to Item
-
Ng, Adeline, Gurpreet Baht, Marc Grynpas, and Benjamin Alman. “Repeated Osteoblast Depletion Decreases Osteogenic Potential of Bone Marrow Stromal Cells in Mice.” In Journal of Bone and Mineral Research, Vol. 28. WILEY-BLACKWELL, 2013.Link to Item
-
Baht, G. S., G. K. Hunter, and H. A. Goldberg. “Bone sialoprotein-mediated mineral formation: Role of phosphorylation & development of a fusion peptide for bone repair.” In European Cells and Materials, 16:43, 2008.
-
Goldberg, H. A., G. Baht, J. Gordon, V. Pitelka, H. Chen, D. Holdsworth, and G. K. Hunter. “Bone repair mediated by bone sialoprotein.” In European Cells and Materials, 16:47, 2008.
-
-
- Teaching & Mentoring
-
Recent Courses
Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.
