Recent Publications
Feature attention graph neural network for estimating brain age and identifying important neural connections in mouse models of genetic risk for Alzheimer’s disease
Journal Article Imaging Neuroscience · July 31, 2024 Alzheimer’s disease (AD), a widely studied neurodegenerative disorder, poses significant research challenges due to its high prevalence and complex etiology. Age, a critical risk factor for AD, is typically assessed by comparing physiological and estimated ... Full text CiteMultivariate investigation of aging in mouse models expressing the Alzheimer's protective APOE2 allele: integrating cognitive metrics, brain imaging, and blood transcriptomics.
Journal Article Brain Struct Funct · January 2024 APOE allelic variation is critical in brain aging and Alzheimer's disease (AD). The APOE2 allele associated with cognitive resilience and neuroprotection against AD remains understudied. We employed a multipronged approach to characterize the transition fr ... Full text Link to item CitePredicting brain age and associated structural networks in mouse models with humanized APOE alleles using integrative and interpretable graph neural networks
Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2024 Alzheimer's disease (AD), a prevalent neurodegenerative disorder, is influenced by an intricate mix of risk factors including age, genetics, and environmental variables. In our study, we employed mouse models with human APOE alleles and nitric oxide syntha ... Full text CiteRecent Grants
Brain networks in mouse models of aging
ResearchResearch Assistant · Awarded by National Institutes of Health · 2019 - 2025View All Grants