Current Appointments & Affiliations
Assistant Research Professor in Molecular Genetics and Microbiology
·
2021 - Present
Molecular Genetics and Microbiology,
Basic Science Departments
Recent Publications
Developmental expression of the Sturge-Weber syndrome-associated genetic mutation in Gnaq: a formal test of Happle's paradominant inheritance hypothesis.
Journal Article Genetics · August 9, 2023 Sturge-Weber Syndrome (SWS) is a sporadic (non-inherited) syndrome characterized by capillary vascular malformations in the facial skin, leptomeninges, or the choroid. A hallmark feature is the mosaic nature of the phenotype. SWS is caused by a somatic mos ... Full text Link to item CiteCardiac Troponin I-Interacting Kinase Affects Cardiomyocyte S-Phase Activity but Not Cardiomyocyte Proliferation.
Journal Article Circulation · January 10, 2023 BACKGROUND: Identifying genetic variants that affect the level of cell cycle reentry and establishing the degree of cell cycle progression in those variants could help guide development of therapeutic interventions aimed at effecting cardiac regeneration. ... Full text Link to item CiteA cross-species approach using an in vivo evaluation platform in mice demonstrates that sequence variation in human RABEP2 modulates ischemic stroke outcomes.
Journal Article Am J Hum Genet · October 6, 2022 Ischemic stroke, caused by vessel blockage, results in cerebral infarction, the death of brain tissue. Previously, quantitative trait locus (QTL) mapping of cerebral infarct volume and collateral vessel number identified a single, strong genetic locus regu ... Full text Open Access Link to item CiteRecent Grants
A consortium effort to translate therapies for neurological diseases via an immune-competent organotypic platform
ResearchSenior Research Associate · Awarded by University of North Carolina - Chapel Hill · 2021 - 2025A novel platform to determine RABEP2 function as a therapeutic target in human ischemic stroke
ResearchPrincipal Investigator · Awarded by American Heart Association · 2022 - 2025ATTRACT: Arterial flow as attractor for endothelial cell migration - a new concept in vascular malformation and stroke regeneration
ResearchPostdoctoral Associate · Awarded by Fondation Leducq · 2018 - 2023View All Grants
Education, Training & Certifications
University of Hamburg (Germany) ·
2011
Ph.D.