Harry Wells Severance Jr.

Harry Wells Severance Jr.
Adjunct Assistant Professor in the Department of Medicine

Acute Cardiology - Chest Pain Presentations

Principle Investigator - Duke E.D. Site - "Speed" Study. Pilot phase of Gusto IV. Investigating Abciximab (a GP IIb-IIIa inhibitor) in combination with rapid access to cardiac cath. Funded through Duke Clinical Research Institute. Multi-center trial.

Principle Investigator - Project: proposed mechanisms for afferent pain transmission from myocardial cells to pain centers. Purpose is to identify potential biochemical markers for early anginal presentations. Funded: grants received from Merck & Co. and Roche-Boehringer-Mannheim. Pilot phase paper - in preparation.

Penetrating Trauma - Blasts/Ballistics

Studying wounding and medical management of penetrating injuries derived from firearms and blast-related injuries.

Impact of Observation/short-stay strategies on clincal care and inpatient/outpatient systems.

Current Appointments & Affiliations

Adjunct Assistant Professor in the Department of Medicine, Medicine, Cardiology, Medicine 2014

Contact Information

0682 Hosp North, Durham, NC 27710
Box 3096 Med Ctr, Durham, NC 27710
harry.severance@duke.edu (919) 668-8821

Background
Education, Training, & Certifications
- M.D., Duke University School of Medicine 1981
Duke Appointment History
- Associate Clinical Professor of Surgery, Surgery, Emergency Medicine, Surgery 2001 - 2004
- Assistant Professor in Medicine, Medicine, Clinical Science Departments 1998 - 2004
- Associate Professor of Surgery, Surgery, Emergency Medicine, Surgery 2001
- Assistant Professor of Surgery, Surgery, Emergency Medicine, Surgery 1996 - 2000
- Assistant Professor in Medicine, Medicine, General Internal Medicine, Medicine 1996 - 1998
- Assistant Professor of Medicine, Medicine, Clinical Science Departments 1991 - 1996
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Severance, HW, and Spiegel, KM. "THE PROTOCOL-PROVIDED CLINICAL RESEARCH MODEL AS AN EVOLVING RESEARCH OPPORTUNITY FOR COMMUNITY-BASED HOSPITALS AND HEALTH CARE FACILITIES." Technology & Innovation 17, no. 4 (March 8, 2016): 211-217. Full Text
  - Ambrosy, AP, Mentz, RJ, Krishnamoorthy, A, Greene, SJ, and Severance, HW. "Identifying Barriers and Practical Solutions to Conducting Site-Based Research in North America: Exploring Acute Heart Failure Trials As a Case Study." Heart failure clinics 11, no. 4 (October 2015): 581-589. (Review) Full Text Open Access Copy
  - Muhlestein, Joseph Boone, Viet Le, David Albert, Fidela Ll Moreno, Jeffrey L. Anderson, Frank Yanowitz, Robert B. Vranian, et al. “Smartphone ECG for evaluation of STEMI: results of the ST LEUIS Pilot Study..” Journal of Electrocardiology 48, no. 2 (March 2015): 249–59. https://doi.org/10.1016/j.jelectrocard.2014.11.005.
    Full Text Open Access Copy
  - Muhlestein, JB, Le, V, Albert, D, Moreno, FL, Anderson, JL, Yanowitz, F, Vranian, RB, Barsness, GW, Bethea, CF, Severance, HW, Ramo, B, Pierce, J, and Barbagelata, A. "Smartphone ECG for evaluation of STEMI: Results of the ST LEUIS Pilot Study." Journal of Electrocardiology 48, no. 2 (January 1, 2015): 249-259. Full Text
  - Severance, HW. "DEVELOPING NEW PATHWAYS FOR CLINICAL RESEARCH THROUGH THE CHANGING ENVIRONMENT OF 21ST CENTURY HEALTHCARE." Technology & Innovation 16, no. 2 (October 23, 2014): 167-170. Full Text Open Access Copy
  - Bledsoe, BE, Nowicki, K, Creel, JH, Carrison, D, and Severance, HW. "Use of Pulse Co-Oximetry as a Screening and Monitoring Tool in Mass Carbon Monoxide Poisoning." Prehospital Emergency Care 14, no. 1 (January 2010): 131-133. Full Text Open Access Copy
  - Tempel, R., and H. W. Severance. “Proposing short-term observation units for the management of decompression illness..” Undersea & Hyperbaric Medicine : Journal of the Undersea and Hyperbaric Medical Society, Inc 33, no. 2 (March 2006): 89–94.
  - Ghim, Michael, and Harry W. Severance. “Ice storm-related carbon monoxide poisonings in North Carolina: a reminder..” Southern Medical Journal 97, no. 11 (November 2004): 1060–65. https://doi.org/10.1097/01.smj.0000144614.38668.60.
    Full Text
  - Severance, Harry W. “Mass-casualty victim "surge" management. Preparing for bombings and blast-related injuries with possibility of hazardous materials exposure..” North Carolina Medical Journal 63, no. 5 (September 2002): 242–46.
  - Bell, S. J., P. N. Leibrandt, J. C. Greenfield, R. H. Selvester, J. Clifton, S. Zhou, C. Maynard, et al. “Comparison of an automated thrombolytic predictive instrument to both diagnostic software and an expert cardiologist for diagnosis of an ST elevation acute myocardial infarction..” Journal of Electrocardiology 33 Suppl (January 2000): 259–62. https://doi.org/10.1054/jelc.2000.20300.
    Full Text
  - Dallara, J., H. W. Severance, B. Davis, and G. Schulz. “Differences between chest pain observation service patients and admitted "rule-out myocardial infarction" patients..” Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine 4, no. 7 (July 1997): 693–98. https://doi.org/10.1111/j.1553-2712.1997.tb03762.x.
    Full Text
  - Pressley, J. C., H. W. Severance, M. P. Raney, R. A. McKinnis, M. W. Smith, M. C. Hindman, B. H. Wilson, and G. S. Wagner. “A comparison of paramedic versus basic emergency medical care of patients at high and low risk during acute myocardial infarction..” Journal of the American College of Cardiology 12, no. 6 (December 1988): 1555–61. https://doi.org/10.1016/s0735-1097(88)80025-1.
    Full Text
  - Pressley, J. C., B. H. Wilson, H. W. Severance, M. P. Raney, R. A. McKinnis, M. W. Smith, M. C. Hindman, and G. S. Wagner. “Basic emergency medical care of patients with acute myocardial infarction: initial prehospital characteristics and in-hospital complications..” Journal of the American College of Cardiology 4, no. 3 (September 1984): 487–92. https://doi.org/10.1016/s0735-1097(84)80091-1.
    Full Text
  - Crimm, A, Severance, HW, Coffey, K, McKinnis, R, Wagner, GS, and Califf, RM. "Prognostic significance of isolated sinus tachycardia during first three days of acute myocardial infarction." The American Journal of Medicine 76, no. 6 (June 1984): 983-988. Full Text
  - Pressley, J. C., M. P. Raney, B. H. Wilson, H. W. Severance, and G. S. Wagner. “Assessment of out-of-hospital resuscitation..” The American Journal of Emergency Medicine 2, no. 3 (May 1984): 215–16. https://doi.org/10.1016/0735-6757(84)90006-8.
    Full Text
  - Wilson, B. H., H. W. Severance, M. P. Raney, J. C. Pressley, R. A. McKinnis, M. C. Hindman, M. Smith, and G. S. Wagner. “Out-of-hospital management of cardiac arrest by basic emergency medical technicians..” The American Journal of Cardiology 53, no. 1 (January 1984): 68–70. https://doi.org/10.1016/0002-9149(84)90685-4.
    Full Text
  - Severance, H. W., and F. H. Bassett. “Rupture of the plantaris--does it exist?.” The Journal of Bone and Joint Surgery. American Volume 64, no. 9 (December 1982): 1387–88.
  - Severance, HW, Morris, KG, and Wagner, GS. "Criteria for early discharge after acute myocardial infarction: validation in a community hospital." Archives of Internal Medicine 142, no. 1 (January 1982): 39-41. Full Text

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Education, Training, & Certifications

Duke Appointment History

Selected Publications

Academic Articles