Barton Ford Haynes
Frederic M. Hanes Distinguished Professor of Medicine
The Haynes lab is studying host innate and adaptive immune responses to the human immunodeficiency virus (HIV), tuberculosis (TB), and influenza in order to find the enabling technology to make preventive vaccines against these three major infectious diseases.
Mucosal Immune Responses in Acute HIV Infection
The Haynes lab is working to determine why broadly neutralizing antibodies are rarely made in acute HIV infection (AHI), currently a major obstacle in the development of an HIV vaccine. The lab has developed a novel approach to define the B cell repertories in AHI in order to find neutralizing antibodies against the virus. This approach uses linear Immunoglobulin (Ig) heavy and light chain gene expression cassettes to express Ig V(H) and V(L) genes isolated from sorted single B cells as IgG1 antibody without a cloning step. This strategy was used to characterize the Ig repertoire of plasma cells/plasmablasts in AHI and to produce recombinant influenza mAbs from sorted single human plasmablasts after influenza vaccination.
The lab is also studying the earliest effect HIV-1 has on B cells. Analyzing blood and gut-associated lymphoid tissues (GALT) during acute HIV infection, they have found that as early as 17 days after transmission HIV-1 induces B cell class switching and 47 days after transmission, HIV-1 causes considerable damage to GALT germinal centers. They found that in AHI, GALT memory B cells induce polyclonal B cell activation due to the presence of HIV-1-specific, influenza-specific, and autoreactive antibodies. The team concluded from this study that early induction of polyclonal B cell differentiation, along with follicular damage and germinal center loss, may explain why HIV-1 induced antibody responses decline rapidly during acute HIV infection and why plasma antibody responses are delayed.
The lab is also looking at ways of generating long-lived memory B cell responses to HIV infection, another major hurdle in the development of a successful HIV-1 vaccine. The lab has found that in HIV-1 gp120 envelope vaccination and chronic HIV-1 infection, HIV-1 envelope induces predominantly short-lived memory B cell-dependent plasma antibodies.
Immunogen Design
To overcome the high level of genetic diversity in HIV-1 envelope genes, the Haynes lab is developing strategies to induce antibodies that cross-react with multiple strains of HIV. The lab has designed immunogens based on transmitted founder Envs and mosaic consensus Envs in collaboration with Dr. Bette Korber at Los Alamos National Laboratory. These immunogens are designed to induce antibodies that cross-react with a multiple subtype Env glycoproteins. The goal is to determine if cross-reactive mAbs to highly conserved epitopes in HIV-1 envelope glycoproteins can be induced. The team recently characterized a panel of ten mAbs that reacted with varying breadth to subtypes A, B, C, D, F, G, CRF01_AE, and a highly divergent SIVcpzUS Env protein. Two of the mAbs cross-reacted with all tested Env proteins, including SIVcpzUS Env and bound Env proteins with high affinity.
Mucosal Immune Responses in TB and Influenza
The Haynes lab is helping to develop novel approaches to TB vaccine development. The current therapeutic vaccine for TB, called BCG, may prevent complications from TB in children, but offers little protection against infection and disease in adults. The lab is focused on using live attenuated Mycobacterium tuberculosis mutants as vaccine candidates and is currently evaluating this approach in non-human primate studies. As part of the DHVI Influenza program, they are studying the B cell response to influenza in order to generate a “universal” flu vaccine. They are currently trying to express more highly conserved influenza antigens in recombinant vesicular stomatitis virus (rVSV) vectors in order to elicit robust T cell and antibody responses to those antigens.
Mucosal Immune Responses in Acute HIV Infection
The Haynes lab is working to determine why broadly neutralizing antibodies are rarely made in acute HIV infection (AHI), currently a major obstacle in the development of an HIV vaccine. The lab has developed a novel approach to define the B cell repertories in AHI in order to find neutralizing antibodies against the virus. This approach uses linear Immunoglobulin (Ig) heavy and light chain gene expression cassettes to express Ig V(H) and V(L) genes isolated from sorted single B cells as IgG1 antibody without a cloning step. This strategy was used to characterize the Ig repertoire of plasma cells/plasmablasts in AHI and to produce recombinant influenza mAbs from sorted single human plasmablasts after influenza vaccination.
The lab is also studying the earliest effect HIV-1 has on B cells. Analyzing blood and gut-associated lymphoid tissues (GALT) during acute HIV infection, they have found that as early as 17 days after transmission HIV-1 induces B cell class switching and 47 days after transmission, HIV-1 causes considerable damage to GALT germinal centers. They found that in AHI, GALT memory B cells induce polyclonal B cell activation due to the presence of HIV-1-specific, influenza-specific, and autoreactive antibodies. The team concluded from this study that early induction of polyclonal B cell differentiation, along with follicular damage and germinal center loss, may explain why HIV-1 induced antibody responses decline rapidly during acute HIV infection and why plasma antibody responses are delayed.
The lab is also looking at ways of generating long-lived memory B cell responses to HIV infection, another major hurdle in the development of a successful HIV-1 vaccine. The lab has found that in HIV-1 gp120 envelope vaccination and chronic HIV-1 infection, HIV-1 envelope induces predominantly short-lived memory B cell-dependent plasma antibodies.
Immunogen Design
To overcome the high level of genetic diversity in HIV-1 envelope genes, the Haynes lab is developing strategies to induce antibodies that cross-react with multiple strains of HIV. The lab has designed immunogens based on transmitted founder Envs and mosaic consensus Envs in collaboration with Dr. Bette Korber at Los Alamos National Laboratory. These immunogens are designed to induce antibodies that cross-react with a multiple subtype Env glycoproteins. The goal is to determine if cross-reactive mAbs to highly conserved epitopes in HIV-1 envelope glycoproteins can be induced. The team recently characterized a panel of ten mAbs that reacted with varying breadth to subtypes A, B, C, D, F, G, CRF01_AE, and a highly divergent SIVcpzUS Env protein. Two of the mAbs cross-reacted with all tested Env proteins, including SIVcpzUS Env and bound Env proteins with high affinity.
Mucosal Immune Responses in TB and Influenza
The Haynes lab is helping to develop novel approaches to TB vaccine development. The current therapeutic vaccine for TB, called BCG, may prevent complications from TB in children, but offers little protection against infection and disease in adults. The lab is focused on using live attenuated Mycobacterium tuberculosis mutants as vaccine candidates and is currently evaluating this approach in non-human primate studies. As part of the DHVI Influenza program, they are studying the B cell response to influenza in order to generate a “universal” flu vaccine. They are currently trying to express more highly conserved influenza antigens in recombinant vesicular stomatitis virus (rVSV) vectors in order to elicit robust T cell and antibody responses to those antigens.
Current Appointments & Affiliations
- Frederic M. Hanes Distinguished Professor of Medicine, Medicine, Duke Human Vaccine Institute, Medicine 1988
- Professor of Medicine, Medicine, Duke Human Vaccine Institute, Medicine 1986
- Director of the Human Vaccine Institute in the Department of Medicine, Medicine, Clinical Science Departments 1999
- Professor of Integrative Immunobiology, Integrative Immunobiology, Basic Science Departments 1995
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1980
- Member of the Duke Human Vaccine Institute, Duke Human Vaccine Institute, Institutes and Centers 2005
Contact Information
- 106 Research Drive, MSRBII 4090, Durham, NC 27710
- DUMC Box 103020, Durham, NC 27710
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hayne002@mc.duke.edu
(919) 684-5384
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Duke Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery
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Duke Human Vaccine Institute website
- Background
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Education, Training, & Certifications
- M.D., Baylor University 1973
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Previous Appointments & Affiliations
- Research Professor of Global Health, Duke Global Health Institute, University Institutes and Centers 2011 - 2020
- Chair, Department of Medicine, Medicine, Clinical Science Departments 1995 - 2002
- Chief, Division of Rheumatology and Immunology in the Department of Medicine, Medicine, Rheumatology and Immunology, Medicine 1987 - 1995
- Professor of Immunology in the Department of Immunology, Integrative Immunobiology, Basic Science Departments 1993 - 1994
- Professor of Immunology in the Department of Immunology, Integrative Immunobiology, Basic Science Departments 1991 - 1992
- Professor of Immunology in the Department of Immunology, Integrative Immunobiology, Basic Science Departments 1989 - 1990
- Professor of Immunology in the Department of Microbiology and Immunology, Integrative Immunobiology, Basic Science Departments 1987 - 1989
- Assistant Professor of Immunology in the Department of Microbiology and Immunology, Molecular Genetics and Microbiology, Basic Science Departments 1981 - 1986
- Associate Professor of Medicine, Medicine, Clinical Science Departments 1984 - 1986
- Associate Professor of Medicine without Tenure, Medicine, Clinical Science Departments 1980 - 1983
- Recognition
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In the News
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MAR 15, 2023 Duke Health News -
JAN 31, 2023 Duke Health News -
OCT 28, 2022 Duke Health News -
OCT 13, 2022 Duke Health News -
SEP 13, 2022 Duke Health News -
MAR 16, 2022 Duke Health News -
NOV 2, 2021 Duke Health News -
OCT 21, 2021 Duke Health News -
MAY 20, 2021 Duke Health News -
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MAY 10, 2021 Duke Health News -
DEC 16, 2020 -
NOV 6, 2020 School of Medicine -
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AUG 20, 2020 Duke Health News -
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MAR 27, 2020 Magnify Magazine -
MAR 2, 2020 Duke Magazine -
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NOV 19, 2019 -
SEP 30, 2019 Duke Health News -
JUL 10, 2019 Duke Health News -
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SEP 27, 2018 Duke Health News -
OCT 16, 2017 Duke Health News -
JUN 9, 2017 Duke Health News -
MAR 21, 2017 Duke Global Health Institute -
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MAR 11, 2016 The Atlantic -
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MAR 12, 2014 LiveScience -
JAN 13, 2014
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Awards & Honors
- Fellow. National Academy of Inventors . April 2016
- Fellow (NAI). National Academy of Inventors. 2015
- Highly Cited Researcher. Thomson Reuters. 2014
- AAI-Steinman Award for Human Immunology Research. American Association of Immunologists. 2013
- Alexander Fleming Award . Infectious Disease Society of America. October 2011
- Alexander Fleming Award. Infectious Diseases Society of America. 2011
- Fellows. American Academy of Arts and Sciences. 2007
- Highly Cited Researcher. Thomson Reuters. 2001
- Distinguished Investigator Award. American College of Rheumatology . October 2000
- Member. Institute of Medicine of The National Academies. 1997
- Member. National Academy of Medicine. 1997
- Lee Howley, Sr. Prize in Basic Research. The Arthritis Foundation . 1995
- Research
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External Relationships
- haynes patents
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Henderson, Rory, Ye Zhou, Victoria Stalls, Kevin Wiehe, Kevin O. Saunders, Kshitij Wagh, Kara Anasti, et al. “Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.” Nat Commun 14, no. 1 (May 15, 2023): 2782. https://doi.org/10.1038/s41467-023-38108-1.Full Text Link to Item
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Haynes, B. F. “HIV Never Sleeps: Evidence to Support Early Antiretroviral Treatment.” Journal of Immunology 210, no. 9 (May 1, 2023): 1181–82. https://doi.org/10.4049/jimmunol.2300035.Full Text
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Caniels, Tom G., Max Medina-Ramírez, Jinsong Zhang, Anita Sarkar, Sonu Kumar, Alex LaBranche, Ronald Derking, et al. “Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.” Cell Rep Med 4, no. 4 (April 18, 2023): 101003. https://doi.org/10.1016/j.xcrm.2023.101003.Full Text Link to Item
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Heggestad, Jacob T., Rhett J. Britton, David S. Kinnamon, Jason Liu, Jack G. Anderson, Daniel Y. Joh, Zachary Quinn, et al. “COVID-19 Diagnosis and SARS-CoV-2 Strain Identification by a Rapid, Multiplexed, Point-of-Care Antibody Microarray.” Anal Chem 95, no. 13 (April 4, 2023): 5610–17. https://doi.org/10.1021/acs.analchem.2c05180.Full Text Open Access Copy Link to Item
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Haynes, Barton F., Kevin Wiehe, Persephone Borrow, Kevin O. Saunders, Bette Korber, Kshitij Wagh, Andrew J. McMichael, et al. “Author Correction: Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies.” Nat Rev Immunol 23, no. 4 (April 2023): 265. https://doi.org/10.1038/s41577-023-00854-0.Full Text Link to Item
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Haynes, Barton F., Kevin Wiehe, Persephone Borrow, Kevin O. Saunders, Bette Korber, Kshitij Wagh, Andrew J. McMichael, et al. “Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies.” Nat Rev Immunol 23, no. 3 (March 2023): 142–58. https://doi.org/10.1038/s41577-022-00753-w.Full Text Link to Item
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Bibollet-Ruche, Frederic, Ronnie M. Russell, Wenge Ding, Weimin Liu, Yingying Li, Kshitij Wagh, Daniel Wrapp, et al. “A Germline-Targeting Chimpanzee SIV Envelope Glycoprotein Elicits a New Class of V2-Apex Directed Cross-Neutralizing Antibodies.” Mbio 14, no. 1 (February 28, 2023): e0337022. https://doi.org/10.1128/mbio.03370-22.Full Text Link to Item
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Cohen, Kristen W., Andrew Fiore-Gartland, Stephen R. Walsh, Karina Yusim, Nicole Frahm, Marnie L. Elizaga, Janine Maenza, et al. “Trivalent mosaic or consensus HIV immunogens prime humoral and broader cellular immune responses in adults.” J Clin Invest 133, no. 4 (February 15, 2023). https://doi.org/10.1172/JCI163338.Full Text Link to Item
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Bennett, A. L., C. Saunders, Y. Bililign, A. Williams, M. Montani, P. Acharya, B. Haynes, and R. C. Henderson. “Examining HIV-1 envelope conformational transitions at high temporal resolution.” Biophysical Journal 122, no. 3S1 (February 10, 2023): 188a-189a. https://doi.org/10.1016/j.bpj.2022.11.1158.Full Text
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Wrapp, Daniel, Zekun Mu, Bhishem Thakur, Katarzyna Janowska, Oluwatobi Ajayi, Maggie Barr, Robert Parks, et al. “Structure-Based Stabilization of SOSIP Env Enhances Recombinant Ectodomain Durability and Yield.” J Virol 97, no. 1 (January 31, 2023): e0167322. https://doi.org/10.1128/jvi.01673-22.Full Text Link to Item
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Vanover, Daryll, Chiara Zurla, Hannah E. Peck, Nichole Orr-Burks, Jae Yeon Joo, Jackelyn Murray, Nathan Holladay, et al. “Nebulized mRNA-Encoded Antibodies Protect Hamsters from SARS-CoV-2 Infection.” Adv Sci (Weinh) 9, no. 34 (December 2022): e2202771. https://doi.org/10.1002/advs.202202771.Full Text Link to Item
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Prévost, Jérémie, Sai Priya Anand, Jyothi Krishnaswamy Rajashekar, Li Zhu, Jonathan Richard, Guillaume Goyette, Halima Medjahed, et al. “HIV-1 Vpu restricts Fc-mediated effector functions in vivo.” Cell Rep 41, no. 6 (November 8, 2022): 111624. https://doi.org/10.1016/j.celrep.2022.111624.Full Text Link to Item
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Luo, Sai, Jun Zhang, Alex J. B. Kreutzberger, Amanda Eaton, Robert J. Edwards, Changbin Jing, Hai-Qiang Dai, et al. “An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion.” Sci Immunol 7, no. 76 (October 28, 2022): eadd5446. https://doi.org/10.1126/sciimmunol.add5446.Full Text Link to Item
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Scarneo, Scott A., Aaron P. Smith, Jacob Favret, Robert O’Connell, Joy Pickeral, Kelly W. Yang, Guido Ferrari, et al. “Expression of membrane Hsp90 is a molecular signature of T cell activation.” Sci Rep 12, no. 1 (October 27, 2022): 18091. https://doi.org/10.1038/s41598-022-22788-8.Full Text Link to Item
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Li, Dapeng, David R. Martinez, Alexandra Schäfer, Haiyan Chen, Maggie Barr, Laura L. Sutherland, Esther Lee, et al. “Breadth of SARS-CoV-2 neutralization and protection induced by a nanoparticle vaccine.” Nat Commun 13, no. 1 (October 23, 2022): 6309. https://doi.org/10.1038/s41467-022-33985-4.Full Text Open Access Copy Link to Item
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Pollara, Justin, Santosh Khanal, R Whitney Edwards, Bhavna Hora, Guido Ferrari, Barton F. Haynes, and Todd Bradley. “Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy.” Bmc Immunol 23, no. 1 (September 29, 2022): 48. https://doi.org/10.1186/s12865-022-00523-2.Full Text Link to Item
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Saunders, Kevin O., Robert J. Edwards, Kedamawit Tilahun, Kartik Manne, Xiaozhi Lu, Derek W. Cain, Kevin Wiehe, et al. “Stabilized HIV-1 envelope immunization induces neutralizing antibodies to the CD4bs and protects macaques against mucosal infection.” Sci Transl Med 14, no. 661 (September 7, 2022): eabo5598. https://doi.org/10.1126/scitranslmed.abo5598.Full Text Open Access Copy Link to Item
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Nelson, Ashley N., Maria Dennis, Jesse F. Mangold, Katherine Li, Pooja T. Saha, Kenneth Cronin, Kaitlyn A. Cross, et al. “Leveraging antigenic seniority for maternal vaccination to prevent mother-to-child transmission of HIV-1.” Npj Vaccines 7, no. 1 (July 30, 2022): 87. https://doi.org/10.1038/s41541-022-00505-w.Full Text Link to Item
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Stalls, Victoria, Jared Lindenberger, Sophie M-C Gobeil, Rory Henderson, Rob Parks, Maggie Barr, Margaret Deyton, et al. “Cryo-EM structures of SARS-CoV-2 Omicron BA.2 spike.” Cell Rep 39, no. 13 (June 28, 2022): 111009. https://doi.org/10.1016/j.celrep.2022.111009.Full Text Link to Item
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Wee, Edmund G., Nathifa A. Moyo, Kevin O. Saunders, Celia LaBranche, Filippo Donati, Silvia Capucci, Robert Parks, et al. “Erratum: Parallel Induction of CH505 B Cell Ontogeny-Guided Neutralizing Antibodies and tHIVconsvX Conserved Mosaic-Specific T Cells against HIV-1.” Mol Ther Methods Clin Dev 25 (June 9, 2022): 490. https://doi.org/10.1016/j.omtm.2022.05.001.Full Text Link to Item
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Gobeil, Sophie M-C, Rory Henderson, Victoria Stalls, Katarzyna Janowska, Xiao Huang, Aaron May, Micah Speakman, et al. “Structural diversity of the SARS-CoV-2 Omicron spike.” Mol Cell 82, no. 11 (June 2, 2022): 2050-2068.e6. https://doi.org/10.1016/j.molcel.2022.03.028.Full Text Link to Item
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Whitley, Jill, Christopher Zwolinski, Christian Denis, Maureen Maughan, Leonie Hayles, David Clarke, Meghan Snare, et al. “Development of mRNA manufacturing for vaccines and therapeutics: mRNA platform requirements and development of a scalable production process to support early phase clinical trials.” Transl Res 242 (April 2022): 38–55. https://doi.org/10.1016/j.trsl.2021.11.009.Full Text Open Access Copy Link to Item
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Li, Dapeng, Simon Brackenridge, Lucy C. Walters, Olivia Swanson, Karl Harlos, Daniel Rozbesky, Derek W. Cain, et al. “Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity.” Commun Biol 5, no. 1 (March 28, 2022): 271. https://doi.org/10.1038/s42003-022-03183-5.Full Text Link to Item
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Mu, Zekun, Kevin Wiehe, Kevin O. Saunders, Rory Henderson, Derek W. Cain, Robert Parks, Diana Martik, et al. “mRNA-encoded HIV-1 Env trimer ferritin nanoparticles induce monoclonal antibodies that neutralize heterologous HIV-1 isolates in mice.” Cell Rep 38, no. 11 (March 15, 2022): 110514. https://doi.org/10.1016/j.celrep.2022.110514.Full Text Link to Item
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Li, Dapeng, Gregory D. Sempowski, Kevin O. Saunders, Priyamvada Acharya, and Barton F. Haynes. “SARS-CoV-2 Neutralizing Antibodies for COVID-19 Prevention and Treatment.” Annu Rev Med 73 (January 27, 2022): 1–16. https://doi.org/10.1146/annurev-med-042420-113838.Full Text Link to Item
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Martinez, David R., Alexandra Schäfer, Sophie Gobeil, Dapeng Li, Gabriela De la Cruz, Robert Parks, Xiaozhi Lu, et al. “A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice.” Sci Transl Med 14, no. 629 (January 26, 2022): eabj7125. https://doi.org/10.1126/scitranslmed.abj7125.Full Text Link to Item
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Mielke, Dieter, Sherry Stanfield-Oakley, Bhavesh Borate, Leigh H. Fisher, Katelyn Faircloth, Marina Tuyishime, Kelli Greene, et al. “Selection of HIV Envelope Strains for Standardized Assessments of Vaccine-Elicited Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies.” J Virol 96, no. 2 (January 26, 2022): e0164321. https://doi.org/10.1128/JVI.01643-21.Full Text Link to Item
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Haynes, Barton F. “Author Correction: SARS-CoV-2 and HIV-1 - A Tale of Two Vaccines.” Nat Rev Immunol 22, no. 1 (January 2022): 66. https://doi.org/10.1038/s41577-021-00671-3.Full Text Link to Item
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Campion, Suzanne L., Elena Brenna, Elaine Thomson, Will Fischer, Kristin Ladell, James E. McLaren, David A. Price, et al. “Preexisting memory CD4+ T cells contribute to the primary response in an HIV-1 vaccine trial.” J Clin Invest 131, no. 23 (December 1, 2021). https://doi.org/10.1172/JCI150823.Full Text Link to Item
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Mu, Zekun, Barton F. Haynes, and Derek W. Cain. “Strategies for eliciting multiple lineages of broadly neutralizing antibodies to HIV by vaccination.” Curr Opin Virol 51 (December 2021): 172–78. https://doi.org/10.1016/j.coviro.2021.09.015.Full Text Link to Item
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Saunders, Kevin O., Norbert Pardi, Robert Parks, Sampa Santra, Zekun Mu, Laura Sutherland, Richard Scearce, et al. “Author Correction: Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates.” Npj Vaccines 6, no. 1 (November 6, 2021): 136. https://doi.org/10.1038/s41541-021-00397-2.Full Text Link to Item
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Cottrell, Christopher A., Kartik Manne, Rui Kong, Shuishu Wang, Tongqing Zhou, Gwo-Yu Chuang, Robert J. Edwards, et al. “Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies.” Cell Reports 37, no. 5 (November 2021): 109922. https://doi.org/10.1016/j.celrep.2021.109922.Full Text
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Williams, Wilton B., Kevin Wiehe, Kevin O. Saunders, and Barton F. Haynes. “Strategies for induction of HIV-1 envelope-reactive broadly neutralizing antibodies.” J Int Aids Soc 24 Suppl 7, no. Suppl 7 (November 2021): e25831. https://doi.org/10.1002/jia2.25831.Full Text Link to Item
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Tomalka, Jeffrey Alan, Adam Nicolas Pelletier, Slim Fourati, Muhammad Bilal Latif, Ashish Sharma, Kathryn Furr, Kevin Carlson, et al. “The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination.” Nat Immunol 22, no. 10 (October 2021): 1294–1305. https://doi.org/10.1038/s41590-021-01026-9.Full Text Link to Item
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Haynes, Barton F. “SARS-CoV-2 and HIV-1 - a tale of two vaccines.” Nat Rev Immunol 21, no. 9 (September 2021): 543–44. https://doi.org/10.1038/s41577-021-00589-w.Full Text Link to Item
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Haynes, Barton F. “Publisher Correction: SARS-CoV-2 and HIV-1 - a tale of two vaccines.” Nat Rev Immunol 21, no. 9 (September 2021): 612. https://doi.org/10.1038/s41577-021-00604-0.Full Text Link to Item
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Swanson, Olivia, Brianna Rhodes, Avivah Wang, Shi-Mao Xia, Robert Parks, Haiyan Chen, Aja Sanzone, et al. “Rapid selection of HIV envelopes that bind to neutralizing antibody B cell lineage members with functional improbable mutations.” Cell Rep 36, no. 7 (August 17, 2021): 109561. https://doi.org/10.1016/j.celrep.2021.109561.Full Text Link to Item
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Gobeil, Sophie M-C, Katarzyna Janowska, Shana McDowell, Katayoun Mansouri, Robert Parks, Victoria Stalls, Megan F. Kopp, et al. “Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.” Science 373, no. 6555 (August 6, 2021). https://doi.org/10.1126/science.abi6226.Full Text Link to Item
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Li, Dapeng, Robert J. Edwards, Kartik Manne, David R. Martinez, Alexandra Schäfer, S Munir Alam, Kevin Wiehe, et al. “In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies.” Cell 184, no. 16 (August 5, 2021): 4203-4219.e32. https://doi.org/10.1016/j.cell.2021.06.021.Full Text Open Access Copy Link to Item
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Fries, Chelsea N., Jui-Lin Chen, Maria L. Dennis, Nicole L. Votaw, Joshua Eudailey, Brian E. Watts, Kelly M. Hainline, et al. “HIV envelope antigen valency on peptide nanofibers modulates antibody magnitude and binding breadth.” Sci Rep 11, no. 1 (July 14, 2021): 14494. https://doi.org/10.1038/s41598-021-93702-x.Full Text Link to Item
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Shiakolas, Andrea R., Kevin J. Kramer, Daniel Wrapp, Simone I. Richardson, Alexandra Schäfer, Steven Wall, Nianshuang Wang, et al. “Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions.” Cell Rep Med 2, no. 6 (June 15, 2021): 100313. https://doi.org/10.1016/j.xcrm.2021.100313.Full Text Link to Item
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Cai, Fangping, Wei-Hung Chen, Weimin Wu, Julia A. Jones, Misook Choe, Neelakshi Gohain, Xiaoying Shen, et al. “Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates.” Plos Pathog 17, no. 6 (June 2021): e1009624. https://doi.org/10.1371/journal.ppat.1009624.Full Text Link to Item
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Saunders, Kevin O., Esther Lee, Robert Parks, David R. Martinez, Dapeng Li, Haiyan Chen, Robert J. Edwards, et al. “Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses.” Nature 594, no. 7864 (June 2021): 553–59. https://doi.org/10.1038/s41586-021-03594-0.Full Text Open Access Copy Link to Item
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Williams, Wilton B., R Ryan Meyerhoff, R. J. Edwards, Hui Li, Kartik Manne, Nathan I. Nicely, Rory Henderson, et al. “Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.” Cell 184, no. 11 (May 27, 2021): 2955-2972.e25. https://doi.org/10.1016/j.cell.2021.04.042.Full Text Open Access Copy Link to Item
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Parker, Robert, Thomas Partridge, Catherine Wormald, Rebeca Kawahara, Victoria Stalls, Maria Aggelakopoulou, Jimmy Parker, et al. “Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells.” Cell Rep 35, no. 8 (May 25, 2021): 109179. https://doi.org/10.1016/j.celrep.2021.109179.Full Text Open Access Copy Link to Item
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Li, Hui, Shuyi Wang, Fang-Hua Lee, Ryan S. Roark, Alex I. Murphy, Jessica Smith, Chengyan Zhao, et al. “New SHIVs and Improved Design Strategy for Modeling HIV-1 Transmission, Immunopathogenesis, Prevention and Cure.” J Virol 95, no. 11 (May 10, 2021). https://doi.org/10.1128/JVI.00071-21.Full Text Open Access Copy Link to Item
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Shen, Xiaoying, Haili Tang, Charlene McDanal, Kshitij Wagh, William Fischer, James Theiler, Hyejin Yoon, et al. “SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral spike vaccines.” Cell Host Microbe 29, no. 4 (April 14, 2021): 529-539.e3. https://doi.org/10.1016/j.chom.2021.03.002.Full Text Link to Item
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Saunders, Kevin O., Norbert Pardi, Robert Parks, Sampa Santra, Zekun Mu, Laura Sutherland, Richard Scearce, et al. “Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates.” Npj Vaccines 6, no. 1 (April 9, 2021): 50. https://doi.org/10.1038/s41541-021-00307-6.Full Text Link to Item
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Tolbert, William D., Verna Van, Rebekah Sherburn, Marina Tuyishime, Fang Yan, Dung N. Nguyen, Sherry Stanfield-Oakley, et al. “Erratum for Tolbert et al., "Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial".” Mbio 12, no. 2 (April 6, 2021). https://doi.org/10.1128/mBio.00474-21.Full Text Link to Item
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Nielsen, Carolyn M., Ane Ogbe, Isabela Pedroza-Pacheco, Susanne E. Doeleman, Yue Chen, Sarah E. Silk, Jordan R. Barrett, et al. “Protein/AS01B vaccination elicits stronger, more Th2-skewed antigen-specific human T follicular helper cell responses than heterologous viral vectors.” Cell Rep Med 2, no. 3 (March 16, 2021): 100207. https://doi.org/10.1016/j.xcrm.2021.100207.Full Text Link to Item
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Chen, W., X. Xiao, E. Streaker, Y. Wang, M. Markowitz, and B. Haynes. “P04-08. Monoclonal antibodies from patient with acute HIV-1 infection.” Retrovirology 6, no. SUPPL. 3 (October 22, 2009). https://doi.org/10.1186/1742-4690-6-S3-P36.Full Text
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Frleta, D., M. O’Brien, B. Haynes, B. Kessler, and N. Bhardwaj. “P10-05. Suppression of human dendritic cell function during acute HIV infection.” Retrovirology 6, no. SUPPL. 3 (October 22, 2009). https://doi.org/10.1186/1742-4690-6-S3-P136.Full Text
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Kirchherr, J. L., J. Hopper, S. Chen, J. Pavlicek, B. Keele, N. Goonetilleke, A. McMichael, B. F. Haynes, and F. Gao. “P20-17. Evolution of multiple transmitted viruses during the early stage of HIV-1 infection.” Retrovirology 6, no. SUPPL. 3 (October 22, 2009). https://doi.org/10.1186/1742-4690-6-S3-P387.Full Text
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Verkoczy, L., M. Diaz, T. M. Holl, Y. Ouyang, H. Bouton-Verville, S. M. Alam, H. Liao, G. Kelsoe, and B. F. Haynes. “P04-26. Immunological tolerance prevents the expression of a broadly reactive neutralizing HIV-1 antibody.” Retrovirology 6, no. SUPPL. 3 (October 22, 2009). https://doi.org/10.1186/1742-4690-6-S3-P54.Full Text
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Holl, T. M., M. Kuraoka, D. Liao, L. Verkoczy, M. A. Moody, M. Alam, H. Liao, B. F. Haynes, and G. H. Kelsoe. “P04-44. Generation of antibody responses to HIV-1 membrane proximal external region (MPER) antigen.” Retrovirology 6, no. SUPPL. 3 (October 22, 2009). https://doi.org/10.1186/1742-4690-6-S3-P72.Full Text
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Dennison, S Moses, Shelley M. Stewart, Kathryn C. Stempel, Hua-Xin Liao, Barton F. Haynes, and S Munir Alam. “Stable docking of neutralizing human immunodeficiency virus type 1 gp41 membrane-proximal external region monoclonal antibodies 2F5 and 4E10 is dependent on the membrane immersion depth of their epitope regions.” J Virol 83, no. 19 (October 2009): 10211–23. https://doi.org/10.1128/JVI.00571-09.Full Text Link to Item
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Go, Eden P., Qing Chang, Hua-Xin Liao, Laura L. Sutherland, S Munir Alam, Barton F. Haynes, and Heather Desaire. “Glycosylation site-specific analysis of clade C HIV-1 envelope proteins.” J Proteome Res 8, no. 9 (September 2009): 4231–42. https://doi.org/10.1021/pr9002728.Full Text Link to Item
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Korber, Bette T., Norman L. Letvin, and Barton F. Haynes. “T-cell vaccine strategies for human immunodeficiency virus, the virus with a thousand faces.” J Virol 83, no. 17 (September 2009): 8300–8314. https://doi.org/10.1128/JVI.00114-09.Full Text Link to Item
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Tomaras, Georgia D., and Barton F. Haynes. “HIV-1-specific antibody responses during acute and chronic HIV-1 infection.” Curr Opin Hiv Aids 4, no. 5 (September 2009): 373–79. https://doi.org/10.1097/COH.0b013e32832f00c0.Full Text Link to Item
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Bonsignori, Mattia, M Anthony Moody, Robert J. Parks, T Matt Holl, Garnett Kelsoe, Charles B. Hicks, Nathan Vandergrift, Georgia D. Tomaras, and Barton F. Haynes. “HIV-1 envelope induces memory B cell responses that correlate with plasma antibody levels after envelope gp120 protein vaccination or HIV-1 infection.” J Immunol 183, no. 4 (August 15, 2009): 2708–17. https://doi.org/10.4049/jimmunol.0901068.Full Text Link to Item
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Perez, Lautaro G., Matthew R. Costa, Christopher A. Todd, Barton F. Haynes, and David C. Montefiori. “Utilization of immunoglobulin G Fc receptors by human immunodeficiency virus type 1: a specific role for antibodies against the membrane-proximal external region of gp41.” J Virol 83, no. 15 (August 2009): 7397–7410. https://doi.org/10.1128/JVI.00656-09.Full Text Link to Item
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Spearman, Paul, Spyros Kalams, Marnie Elizaga, Barbara Metch, Ya-Lin Chiu, Mary Allen, Kent J. Weinhold, et al. “Safety and immunogenicity of a CTL multiepitope peptide vaccine for HIV with or without GM-CSF in a phase I trial.” Vaccine 27, no. 2 (January 7, 2009): 243–49. https://doi.org/10.1016/j.vaccine.2008.10.051.Full Text Link to Item
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Bonsignori, M., K. Hwang, N. Vandergrift, M. A. Moody, and B. F. Haynes. “P04-01. Simultaneous enumeration of HIV-1 gp41 Env-specific IgG and IgM antibody-secreting cells with a multiplex B-cell fluorospot assay.” Retrovirology 6, no. Suppl 3 (January 2009): P29–P29. https://doi.org/10.1186/1742-4690-6-s3-p29.Full Text
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Qiu, Liyou, Dan Huang, Cystal Y. Chen, Richard Wang, Ling Shen, Yun Shen, Robert Hunt, et al. “Severe tuberculosis induces unbalanced up-regulation of gene networks and overexpression of IL-22, MIP-1alpha, CCL27, IP-10, CCR4, CCR5, CXCR3, PD1, PDL2, IL-3, IFN-beta, TIM1, and TLR2 but low antigen-specific cellular responses.” J Infect Dis 198, no. 10 (November 15, 2008): 1514–19. https://doi.org/10.1086/592448.Full Text Link to Item
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Barefoot, Brice, Natalie J. Thornburg, Daniel H. Barouch, Jae-Sung Yu, Christopher Sample, Robert E. Johnston, Hua Xin Liao, Thomas B. Kepler, Barton F. Haynes, and Elizabeth Ramsburg. “Comparison of multiple vaccine vectors in a single heterologous prime-boost trial.” Vaccine 26, no. 48 (November 11, 2008): 6108–18. https://doi.org/10.1016/j.vaccine.2008.09.007.Full Text Link to Item
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Moody, M Anthony, and Barton F. Haynes. “Antigen-specific B cell detection reagents: use and quality control.” Cytometry A 73, no. 11 (November 2008): 1086–92. https://doi.org/10.1002/cyto.a.20599.Full Text Link to Item
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Gasper-Smith, Nancy, Deanna M. Crossman, John F. Whitesides, Nadia Mensali, Janet S. Ottinger, Steven G. Plonk, M Anthony Moody, et al. “Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design.” J Virol 82, no. 15 (August 2008): 7700–7710. https://doi.org/10.1128/JVI.00605-08.Full Text Link to Item
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Irungu, Janet, Eden P. Go, Ying Zhang, Dilusha S. Dalpathado, Hua-Xin Liao, Barton F. Haynes, and Heather Desaire. “Comparison of HPLC/ESI-FTICR MS versus MALDI-TOF/TOF MS for glycopeptide analysis of a highly glycosylated HIV envelope glycoprotein.” J Am Soc Mass Spectrom 19, no. 8 (August 2008): 1209–20. https://doi.org/10.1016/j.jasms.2008.05.010.Full Text Link to Item
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Santra, Sampa, Bette T. Korber, Mark Muldoon, Dan H. Barouch, Gary J. Nabel, Feng Gao, Beatrice H. Hahn, Barton F. Haynes, and Norman L. Letvin. “A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys.” Proc Natl Acad Sci U S A 105, no. 30 (July 29, 2008): 10489–94. https://doi.org/10.1073/pnas.0803352105.Full Text Link to Item
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Haynes, Barton F., and Robin J. Shattock. “Critical issues in mucosal immunity for HIV-1 vaccine development.” J Allergy Clin Immunol 122, no. 1 (July 2008): 3–9. https://doi.org/10.1016/j.jaci.2008.03.036.Full Text Link to Item
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Zhang, Mei-Yun, Bang K. Vu, Anil Choudhary, Hong Lu, Michael Humbert, Helena Ong, Munir Alam, et al. “Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens.” J Virol 82, no. 14 (July 2008): 6869–79. https://doi.org/10.1128/JVI.00033-08.Full Text Link to Item
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Keele, Brandon F., Elena E. Giorgi, Jesus F. Salazar-Gonzalez, Julie M. Decker, Kimmy T. Pham, Maria G. Salazar, Chuanxi Sun, et al. “Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection.” Proc Natl Acad Sci U S A 105, no. 21 (May 27, 2008): 7552–57. https://doi.org/10.1073/pnas.0802203105.Full Text Link to Item
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Go, Eden P., Janet Irungu, Ying Zhang, Dilusha S. Dalpathado, Hua-Xin Liao, Laura L. Sutherland, S Munir Alam, Barton F. Haynes, and Heather Desaire. “Glycosylation site-specific analysis of HIV envelope proteins (JR-FL and CON-S) reveals major differences in glycosylation site occupancy, glycoform profiles, and antigenic epitopes' accessibility.” J Proteome Res 7, no. 4 (April 2008): 1660–74. https://doi.org/10.1021/pr7006957.Full Text Link to Item
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Howard, Brandon A., Gregory D. Sempowski, Richard M. Scearce, Hua-Xin Liao, David M. Lee, Gordon K. Lam, Haiyen Chen, Patrick Fadden, Timothy Haystead, and Barton F. Haynes. “Murine CD7 shares antigenic cross-reactivity with HSP-60.” Hybridoma (Larchmt) 27, no. 2 (April 2008): 81–89. https://doi.org/10.1089/hyb.2007.0553.Full Text Link to Item
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Shattock, Robin J., Barton F. Haynes, Bali Pulendran, Jorge Flores, José Esparza, and José Working Group convened by the Global HIV Vaccine Enterprise. “Improving defences at the portal of HIV entry: mucosal and innate immunity.” Plos Med 5, no. 4 (April 1, 2008): e81. https://doi.org/10.1371/journal.pmed.0050081.Full Text Link to Item
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Fischer, Will, H. X. Liao, Barton F. Haynes, Norman L. Letvin, and Bette Korber. “Coping with viral diversity in HIV vaccine design: a response to Nickle et al.” Plos Comput Biol 4, no. 1 (January 2008): e15. https://doi.org/10.1371/journal.pcbi.0040015.Full Text Link to Item
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Gao, Feng, Hua-Xin Liao, Beatrice H. Hahn, Norman L. Letvin, Bette T. Korber, and Barton F. Haynes. “Centralized HIV-1 envelope immunogens and neutralizing antibodies.” Curr Hiv Res 5, no. 6 (November 2007): 572–77. https://doi.org/10.2174/157016207782418498.Full Text Link to Item
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Staats, Herman F., S Munir Alam, Richard M. Scearce, Shaun M. Kirwan, Julia Xianzhi Zhang, William M. Gwinn, and Barton F. Haynes. “In vitro and in vivo characterization of anthrax anti-protective antigen and anti-lethal factor monoclonal antibodies after passive transfer in a mouse lethal toxin challenge model to define correlates of immunity.” Infect Immun 75, no. 11 (November 2007): 5443–52. https://doi.org/10.1128/IAI.00529-07.Full Text Link to Item
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Wang, Bao-Zhong, Weimin Liu, Sang-Moo Kang, Munir Alam, Chunzi Huang, Ling Ye, Yuliang Sun, et al. “Incorporation of high levels of chimeric human immunodeficiency virus envelope glycoproteins into virus-like particles.” J Virol 81, no. 20 (October 2007): 10869–78. https://doi.org/10.1128/JVI.00542-07.Full Text Link to Item
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Hudson, Lori L., M. Louise Markert, Blythe H. Devlin, Barton F. Haynes, and Gregory D. Sempowski. “Human T cell reconstitution in DiGeorge syndrome and HIV-1 infection.” Semin Immunol 19, no. 5 (October 2007): 297–309. https://doi.org/10.1016/j.smim.2007.10.002.Full Text Link to Item
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Fellay, Jacques, Kevin V. Shianna, Dongliang Ge, Sara Colombo, Bruno Ledergerber, Mike Weale, Kunlin Zhang, et al. “A whole-genome association study of major determinants for host control of HIV-1.” Science 317, no. 5840 (August 17, 2007): 944–47. https://doi.org/10.1126/science.1143767.Full Text Link to Item
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Kirchherr, Jennifer L., Xiaozhi Lu, Webster Kasongo, Victor Chalwe, Lawrence Mwananyanda, Rosemary M. Musonda, Shi-Mao Xia, et al. “High throughput functional analysis of HIV-1 env genes without cloning.” J Virol Methods 143, no. 1 (July 2007): 104–11. https://doi.org/10.1016/j.jviromet.2007.02.015.Full Text Link to Item
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Yu, Jae-Sung, James W. Peacock, William R. Jacobs, Richard Frothingham, Norman L. Letvin, Hua-Xin Liao, and Barton F. Haynes. “Recombinant Mycobacterium bovis bacillus Calmette-Guerin elicits human immunodeficiency virus type 1 envelope-specific T lymphocytes at mucosal sites.” Clin Vaccine Immunol 14, no. 7 (July 2007): 886–93. https://doi.org/10.1128/CVI.00407-06.Full Text Link to Item
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Alam, S Munir, Mildred McAdams, David Boren, Michael Rak, Richard M. Scearce, Feng Gao, Zenaido T. Camacho, et al. “The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes.” J Immunol 178, no. 7 (April 1, 2007): 4424–35. https://doi.org/10.4049/jimmunol.178.7.4424.Full Text Link to Item
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Verkoczy, Laurent, Anthony Moody, Richard Scearce, Laura Sutherland, Stacie VanLeeuwen, Kelly Plonk, Derek Cain, Garnett Kelsoe, and Barton Haynes. “Identification of HIV gp41 membrane proximal epitope tetramer reactive populations of B220(+) B cells and B220(lo/neg) basophils in gp41 peptide-immunized mice.” Journal of Immunology 178 (April 1, 2007).Link to Item
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Kothe, Denise L., Julie M. Decker, Yingying Li, Zhiping Weng, Frederic Bibollet-Ruche, Kenneth P. Zammit, Maria G. Salazar, et al. “Antigenicity and immunogenicity of HIV-1 consensus subtype B envelope glycoproteins.” Virology 360, no. 1 (March 30, 2007): 218–34. https://doi.org/10.1016/j.virol.2006.10.017.Full Text Link to Item
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Fischer, Will, Simon Perkins, James Theiler, Tanmoy Bhattacharya, Karina Yusim, Robert Funkhouser, Carla Kuiken, et al. “Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants.” Nat Med 13, no. 1 (January 2007): 100–106. https://doi.org/10.1038/nm1461.Full Text Link to Item
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Hovav, Avi-Hai, Mark J. Cayabyab, Michael W. Panas, Sampa Santra, John Greenland, Ralf Geiben, Barton F. Haynes, William R. Jacobs, and Norman L. Letvin. “Rapid memory CD8+ T-lymphocyte induction through priming with recombinant Mycobacterium smegmatis.” J Virol 81, no. 1 (January 2007): 74–83. https://doi.org/10.1128/JVI.01269-06.Full Text Link to Item
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Haynes, Barton F. “Gut microbes out of control in HIV infection.” Nat Med 12, no. 12 (December 2006): 1351–52. https://doi.org/10.1038/nm1206-1351.Full Text Link to Item
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Yu, Jae-Sung, Hua-Xin Liao, Aren E. Gerdon, Brian Huffman, Richard M. Scearce, Mille McAdams, S Munir Alam, et al. “Detection of Ebola virus envelope using monoclonal and polyclonal antibodies in ELISA, surface plasmon resonance and a quartz crystal microbalance immunosensor.” J Virol Methods 137, no. 2 (November 2006): 219–28. https://doi.org/10.1016/j.jviromet.2006.06.014.Full Text Link to Item
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Yu, Jae-Sung, James W. Peacock, Stacie Vanleeuwen, Tsungda Hsu, William R. Jacobs, Mark J. Cayabyab, Norman L. Letvin, et al. “Generation of mucosal anti-human immunodeficiency virus type 1 T-cell responses by recombinant Mycobacterium smegmatis.” Clin Vaccine Immunol 13, no. 11 (November 2006): 1204–11. https://doi.org/10.1128/CVI.00195-06.Full Text Link to Item
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Liao, Hua-Xin, Laura L. Sutherland, Shi-Mao Xia, Mary E. Brock, Richard M. Scearce, Stacie Vanleeuwen, S Munir Alam, et al. “A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses.” Virology 353, no. 2 (September 30, 2006): 268–82. https://doi.org/10.1016/j.virol.2006.04.043.Full Text Link to Item
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Kothe, Denise L., Yingying Li, Julie M. Decker, Frederic Bibollet-Ruche, Kenneth P. Zammit, Maria G. Salazar, Yalu Chen, et al. “Ancestral and consensus envelope immunogens for HIV-1 subtype C.” Virology 352, no. 2 (September 1, 2006): 438–49. https://doi.org/10.1016/j.virol.2006.05.011.Full Text Link to Item
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Haynes, B. F., and D. C. Monterfori. “Erratum: Aiming to induce broadly reactive neutralizing antibody responses with HIV-1 vaccine candidates (Expert Review of Vaccines (2006) 5, 3, (347-363)).” Expert Review of Vaccines 5, no. 4 (August 1, 2006): 578. https://doi.org/10.1586/14760584.5.4.578.Full Text
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Haynes, Barton F., and David C. Montefiori. “Aiming to induce broadly reactive neutralizing antibody responses with HIV-1 vaccine candidates.” Expert Rev Vaccines 5, no. 4 (August 2006): 579–95. https://doi.org/10.1586/14760584.5.4.579.Full Text Link to Item
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Haynes, Barton F., and David C. Monterfori. “Aiming to induce broadly reactive neutralizing antibody responses with HIV-1 vaccine candidates (vol 5, pg 347, 2006).” Expert Review of Vaccines 5, no. 4 (August 1, 2006): 578–95.Link to Item
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Weaver, Eric A., Zhongjing Lu, Zenaido T. Camacho, Fatiha Moukdar, Hua-Xin Liao, Ben-Jiang Ma, Mark Muldoon, et al. “Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group m consensus env immunogen.” J Virol 80, no. 14 (July 2006): 6745–56. https://doi.org/10.1128/JVI.02484-05.Full Text Link to Item
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Hick, Ryan W., Amanda L. Gruver, Melissa S. Ventevogel, Barton F. Haynes, and Gregory D. Sempowski. “Leptin selectively augments thymopoiesis in leptin deficiency and lipopolysaccharide-induced thymic atrophy.” J Immunol 177, no. 1 (July 1, 2006): 169–76. https://doi.org/10.4049/jimmunol.177.1.169.Full Text Link to Item
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Haynes, Barton F., and David C. Montefiori. “Aiming to induce broadly reactive neutralizing antibody responses with HIV-1 vaccine candidates.” Expert Rev Vaccines 5, no. 3 (June 2006): 347–63. https://doi.org/10.1586/14760584.5.3.347.Full Text Link to Item
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Haynes, Barton F., Benjiang Ma, David C. Montefiori, Terri Wrin, Christos J. Petropoulos, Laura L. Sutherland, Richard M. Scearce, et al. “Analysis of HIV-1 subtype B third variable region peptide motifs for induction of neutralizing antibodies against HIV-1 primary isolates.” Virology 345, no. 1 (February 5, 2006): 44–55. https://doi.org/10.1016/j.virol.2005.08.042.Full Text Link to Item
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Cayabyab, Mark J., Avi-Hai Hovav, Tsungda Hsu, Georgia R. Krivulka, Michelle A. Lifton, Darci A. Gorgone, Glenn J. Fennelly, Barton F. Haynes, William R. Jacobs, and Norman L. Letvin. “Generation of CD8+ T-cell responses by a recombinant nonpathogenic Mycobacterium smegmatis vaccine vector expressing human immunodeficiency virus type 1 Env.” J Virol 80, no. 4 (February 2006): 1645–52. https://doi.org/10.1128/JVI.80.4.1645-1652.2006.Full Text Link to Item
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Sempowski, Gregory D., Charles B. Hicks, Joseph J. Eron, John A. Bartlett, Laura P. Hale, Guido Ferrari, Lloyd J. Edwards, Susan Fiscus, and Barton F. Haynes. “Naïve T cells are maintained in the periphery during the first 3 months of acute HIV-1 infection: implications for analysis of thymus function.” J Clin Immunol 25, no. 5 (September 2005): 462–72. https://doi.org/10.1007/s10875-005-5635-4.Full Text Link to Item
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Haynes, Barton F., Judith Fleming, E William St Clair, Herman Katinger, Gabriela Stiegler, Renate Kunert, James Robinson, et al. “Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.” Science 308, no. 5730 (June 24, 2005): 1906–8. https://doi.org/10.1126/science.1111781.Full Text Link to Item
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Gao, Feng, Eric A. Weaver, Zhongjing Lu, Yingying Li, Hua-Xin Liao, Benjiang Ma, S Munir Alam, et al. “Antigenicity and immunogenicity of a synthetic human immunodeficiency virus type 1 group m consensus envelope glycoprotein.” J Virol 79, no. 2 (January 2005): 1154–63. https://doi.org/10.1128/JVI.79.2.1154-1163.2005.Full Text Link to Item
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Kim, Mikyung, Zhi-Song Qiao, David C. Montefiori, Barton F. Haynes, Ellis L. Reinherz, and Hua-Xin Liao. “Comparison of HIV Type 1 ADA gp120 monomers versus gp140 trimers as immunogens for the induction of neutralizing antibodies.” Aids Res Hum Retroviruses 21, no. 1 (January 2005): 58–67. https://doi.org/10.1089/aid.2005.21.58.Full Text Link to Item
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Haynes, Barton F., M Anthony Moody, Laurent Verkoczy, Garnett Kelsoe, and S Munir Alam. “Antibody polyspecificity and neutralization of HIV-1: a hypothesis.” Hum Antibodies 14, no. 3–4 (2005): 59–67.Link to Item
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Haynes, Barton. “An interview with Barton Haynes. A new virtual center. Interview by Simon Noble.” Iavi Rep 9, no. 4 (2005): 14–17.Link to Item
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Lam, Gordon K., Hua-Xin Liao, Yan Xue, S Munir Alam, Richard M. Scearce, Russel E. Kaufman, Gregory D. Sempowski, and Barton F. Haynes. “Expression of the CD7 ligand K-12 in human thymic epithelial cells: regulation by IFN-gamma.” J Clin Immunol 25, no. 1 (January 2005): 41–49. https://doi.org/10.1007/s10875-005-0356-5.Full Text Link to Item
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Peacock, James W., Sushila K. Nordone, Shawn S. Jackson, Hua-Xin Liao, Norman L. Letvin, Alicia Gomez Yafal, Linda Gritz, Gail P. Mazzara, Barton F. Haynes, and Herman F. Staats. “Gender differences in human immunodeficiency virus type 1-specific CD8 responses in the reproductive tract and colon following nasal peptide priming and modified vaccinia virus Ankara boosting.” J Virol 78, no. 23 (December 2004): 13163–72. https://doi.org/10.1128/JVI.78.23.13163-13172.2004.Full Text Link to Item
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Egan, Michael A., Siew Yen Chong, Michael Hagen, Shakuntala Megati, Eva B. Schadeck, Priscilla Piacente, Ben-Jiang Ma, et al. “A comparative evaluation of nasal and parenteral vaccine adjuvants to elicit systemic and mucosal HIV-1 peptide-specific humoral immune responses in cynomolgus macaques.” Vaccine 22, no. 27–28 (September 9, 2004): 3774–88. https://doi.org/10.1016/j.vaccine.2004.03.011.Full Text Link to Item
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Alam, S Munir, Casey A. Paleos, Hua-Xin Liao, Richard Scearce, James Robinson, and Barton F. Haynes. “An inducible HIV type 1 gp41 HR-2 peptide-binding site on HIV type 1 envelope gp120.” Aids Res Hum Retroviruses 20, no. 8 (August 2004): 836–45. https://doi.org/10.1089/0889222041725181.Full Text Link to Item
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Gao, Feng, Bette T. Korber, Eric Weaver, Hua-Xin Liao, Beatrice H. Hahn, and Barton F. Haynes. “Centralized immunogens as a vaccine strategy to overcome HIV-1 diversity.” Expert Rev Vaccines 3, no. 4 Suppl (August 2004): S161–68. https://doi.org/10.1586/14760584.3.4.s161.Full Text Link to Item
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Liao, Hua-Xin, S Munir Alam, John R. Mascola, James Robinson, Benjiang Ma, David C. Montefiori, Maria Rhein, Laura L. Sutherland, Richard Scearce, and Barton F. Haynes. “Immunogenicity of constrained monoclonal antibody A32-human immunodeficiency virus (HIV) Env gp120 complexes compared to that of recombinant HIV type 1 gp120 envelope glycoproteins.” J Virol 78, no. 10 (May 2004): 5270–78. https://doi.org/10.1128/jvi.78.10.5270-5278.2004.Full Text Link to Item
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Klausner, R. D., A. S. Fauci, L. Corey, G. J. Nabel, H. Gayle, S. Berkley, B. F. Haynes, et al. “The challenges of an HIV vaccine enterprise - Response.” Science 303, no. 5662 (February 27, 2004): 1296–97.Link to Item
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Zinkernagel, Rolf M. “The challenges of an HIV vaccine enterprise.” Science 303, no. 5662 (February 27, 2004): 1294–97. https://doi.org/10.1126/science.303.5662.1294.Full Text Link to Item
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Sempowski, Gregory D., Scott J. Cross, Craig S. Heinly, Richard M. Scearce, and Barton F. Haynes. “CD7 and CD28 are required for murine CD4+CD25+ regulatory T cell homeostasis and prevention of thyroiditis.” J Immunol 172, no. 2 (January 15, 2004): 787–94. https://doi.org/10.4049/jimmunol.172.2.787.Full Text Link to Item
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Markert, M Louise, Marcella Sarzotti, Daniel A. Ozaki, Gregory D. Sempowski, Maria E. Rhein, Laura P. Hale, Francoise Le Deist, et al. “Thymus transplantation in complete DiGeorge syndrome: immunologic and safety evaluations in 12 patients.” Blood 102, no. 3 (August 1, 2003): 1121–30. https://doi.org/10.1182/blood-2002-08-2545.Full Text Link to Item
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Klausner, Richard D., Anthony S. Fauci, Lawrence Corey, Gary J. Nabel, Helene Gayle, Seth Berkley, Barton F. Haynes, et al. “Medicine. The need for a global HIV vaccine enterprise.” Science 300, no. 5628 (June 27, 2003): 2036–39. https://doi.org/10.1126/science.1086916.Full Text Link to Item
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Gao, F., T. Bhattacharya, B. Gaschen, J. Taylor, J. P. Moore, V. Novitsky, K. Yusim, et al. “Consensus and ancestral state HIV vaccines - Response.” Science 299, no. 5612 (March 7, 2003): 1517–18.Link to Item
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Nickle, David C., Mark A. Jensen, Geoffrey S. Gottlieb, Daniel Shriner, Gerald H. Learn, Allen G. Rodrigo, and James I. Mullins. “Consensus and ancestral state HIV vaccines.” Science 299, no. 5612 (March 7, 2003): 1515–18. https://doi.org/10.1126/science.299.5612.1515c.Full Text Link to Item
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Sempowski, Gregory D., Maria E. Rhein, Richard M. Scearce, and Barton F. Haynes. “Leukemia inhibitory factor is a mediator of Escherichia coli lipopolysaccharide-induced acute thymic atrophy.” Eur J Immunol 32, no. 11 (November 2002): 3066–70. https://doi.org/10.1002/1521-4141(200211)32:11<3066::AID-IMMU3066>3.0.CO;2-J.Full Text Link to Item
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Gaschen, Brian, Jesse Taylor, Karina Yusim, Brian Foley, Feng Gao, Dorothy Lang, Vladimir Novitsky, et al. “Diversity considerations in HIV-1 vaccine selection.” Science 296, no. 5577 (June 28, 2002): 2354–60. https://doi.org/10.1126/science.1070441.Full Text Link to Item
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Liao, Hua Xin, George J. Cianciolo, Herman F. Staats, Richard M. Scearce, Dana M. Lapple, Stephen H. Stauffer, James R. Thomasch, et al. “Increased immunogenicity of HIV envelope subunit complexed with alpha2-macroglobulin when combined with monophosphoryl lipid A and GM-CSF.” Vaccine 20, no. 17–18 (May 22, 2002): 2396–2403. https://doi.org/10.1016/s0264-410x(02)00090-7.Full Text Link to Item
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Haynes, Barton F., and Gregory D. Sempowski. “Protection from death in endotoxin shock: does fish oil need a LIF?” Crit Care Med 30, no. 5 (May 2002): 1174–75. https://doi.org/10.1097/00003246-200205000-00045.Full Text Link to Item
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Gooding, M. E., G. D. Sempowski, and B. F. Haynes. “The thymus is the predominant site of T cell rearrangement in early human T cell development.” Faseb Journal 16, no. 4 (March 20, 2002): A346–A346.Link to Item
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Sempowski, G. D., C. S. Heinly, D. M. Lee, R. M. Scearce, and B. F. Haynes. “CD7 and CD28 play a critical role in the development of CD4 T regulatory cells.” Faseb Journal 16, no. 4 (March 20, 2002): A342–A342.Link to Item
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Sempowski, Gregory D., Maria E. Gooding, H. X. Liao, Phong T. Le, and Barton F. Haynes. “T cell receptor excision circle assessment of thymopoiesis in aging mice.” Mol Immunol 38, no. 11 (March 2002): 841–48. https://doi.org/10.1016/s0161-5890(01)00122-5.Full Text Link to Item
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Bradney, Curtis P., Gregory D. Sempowski, Hua-Xin Liao, Barton F. Haynes, and Herman F. Staats. “Cytokines as adjuvants for the induction of anti-human immunodeficiency virus peptide immunoglobulin G (IgG) and IgA antibodies in serum and mucosal secretions after nasal immunization.” J Virol 76, no. 2 (January 2002): 517–24. https://doi.org/10.1128/jvi.76.2.517-524.2002.Full Text Link to Item
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Chen, Benny J., Xiuyu Cui, Gregory D. Sempowski, Maria E. Gooding, Congxiao Liu, Barton F. Haynes, and Nelson J. Chao. “A comparison of murine T-cell-depleted adult bone marrow and full-term fetal blood cells in hematopoietic engraftment and immune reconstitution.” Blood 99, no. 1 (January 1, 2002): 364–71. https://doi.org/10.1182/blood.v99.1.364.Full Text Link to Item
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Sempowski, G. D., M. E. Gooding, P. T. Le, and B. F. Haynes. “Erratum: Corrigendum to "T Cell receptor excision circle assessment of thymopoieses in aging mice" (MIMM (2001) 38: 11 (841-848) PII S0161589001001225).” Molecular Immunology 39, no. 5–6 (January 1, 2002): 379–80. https://doi.org/10.1016/S0161-5890(02)00112-8.Full Text
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Sempowski, Gregory D., and Barton F. Haynes. “Immune reconstitution in patients with HIV infection.” Annu Rev Med 53 (2002): 269–84. https://doi.org/10.1146/annurev.med.53.082901.104032.Full Text Link to Item
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Markert, M. L., A. P. Alvarez-McLeod, G. D. Sempowski, L. P. Hale, J. M. Horvatinovich, K. J. Weinhold, J. A. Bartlett, T. A. D’Amico, and B. F. Haynes. “Thymopoiesis in HIV-infected adults after highly active antiretroviral therapy.” Aids Res Hum Retroviruses 17, no. 17 (November 20, 2001): 1635–43. https://doi.org/10.1089/088922201753342040.Full Text Link to Item
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Staats, H. F., C. P. Bradney, W. M. Gwinn, S. S. Jackson, G. D. Sempowski, H. X. Liao, N. L. Letvin, and B. F. Haynes. “Cytokine requirements for induction of systemic and mucosal CTL after nasal immunization.” J Immunol 167, no. 9 (November 1, 2001): 5386–94. https://doi.org/10.4049/jimmunol.167.9.5386.Full Text Link to Item
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Haynes, B. F., and G. D. Sempowski. “Can the thymus win the battle against drug-resistant HIV?” Nat Med 7, no. 6 (June 2001): 661–62. https://doi.org/10.1038/89028.Full Text Link to Item
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Tchilian, E. Z., D. L. Wallace, N. Imami, H. X. Liao, C. Burton, F. Gotch, J. Martinson, B. F. Haynes, and P. C. Beverley. “The exon A (C77G) mutation is a common cause of abnormal CD45 splicing in humans.” J Immunol 166, no. 10 (May 15, 2001): 6144–48. https://doi.org/10.4049/jimmunol.166.10.6144.Full Text Link to Item
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Letvin, N. L., S. Robinson, D. Rohne, M. K. Axthelm, J. W. Fanton, M. Bilska, T. J. Palker, H. X. Liao, B. F. Haynes, and D. C. Montefiori. “Vaccine-elicited V3 loop-specific antibodies in rhesus monkeys and control of a simian-human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate envelope.” J Virol 75, no. 9 (May 2001): 4165–75. https://doi.org/10.1128/JVI.75.9.4165-4175.2001.Full Text Link to Item
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Wells, A. F., G. Sempowski, R. Scearce, M. Gooding, and B. F. Haynes. “The role of ciliary neurotropic factor in regulation of thymopoeisis.” Faseb Journal 15, no. 5 (March 8, 2001): A1057–A1057.Link to Item
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Lam, G. K., H. X. Liao, Y. Xue, S. M. Alam, J. R. Thomasch, G. D. Sempowski, S. H. Stauffer, R. Kaufman, and B. F. Haynes. “Characterisation and expression of CD7 ligand, K-12, in human thymic epithelial cells.” Faseb Journal 15, no. 5 (March 8, 2001): A1033–A1033.Link to Item
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Sempowski, G. D., M. E. Gooding, R. M. Scearce, and B. F. Haynes. “Role of leukemia inhibitory factor and corticosteroids in the pathogenesis of lipopolysaccharride-induced acute thymic atrophy.” Faseb Journal 15, no. 5 (March 8, 2001): A1057–A1057.Link to Item
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Sempowski, G. D., M. E. Gooding, P. T. Le, H. X. Liao, and B. F. Haynes. “Molecular characterization of thymic output in aging mice using signal joint T cell receptor delta excision circles.” Faseb Journal 15, no. 4 (March 7, 2001): A667–A667.Link to Item
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Sempowski, G., J. Thomasch, M. Gooding, L. Hale, L. Edwards, E. Ciafaloni, D. Sanders, et al. “Effect of thymectomy on human peripheral blood T cell pools in myasthenia gravis.” J Immunol 166, no. 4 (February 15, 2001): 2808–17. https://doi.org/10.4049/jimmunol.166.4.2808.Full Text Link to Item
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Heinly, C. S., G. D. Sempowski, D. M. Lee, D. D. Patel, P. M. McDermott, R. M. Scearce, C. B. Thompson, and B. F. Haynes. “Comparison of thymocyte development and cytokine production in CD7-deficient, CD28-deficient and CD7/CD28 double-deficient mice.” Int Immunol 13, no. 2 (February 2001): 157–66. https://doi.org/10.1093/intimm/13.2.157.Full Text Link to Item
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Brugarolas, J., B. F. Haynes, and J. R. Nevins. “Towards a genomic-based diagnosis.” Lancet 357, no. 9252 (January 27, 2001): 249–50. https://doi.org/10.1016/S0140-6736(00)03608-4.Full Text Link to Item
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Levesque, M. C., and B. F. Haynes. “Activated T lymphocytes regulate hyaluronan binding to monocyte CD44 via production of IL-2 and IFN-gamma.” J Immunol 166, no. 1 (January 1, 2001): 188–96. https://doi.org/10.4049/jimmunol.166.1.188.Full Text Link to Item
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Klein, A. K., D. D. Patel, M. E. Gooding, G. D. Sempowski, B. J. Chen, C. Liu, J. Kurtzberg, B. F. Haynes, and N. J. Chao. “T-Cell recovery in adults and children following umbilical cord blood transplantation.” Biol Blood Marrow Transplant 7, no. 8 (2001): 454–66. https://doi.org/10.1016/s1083-8791(01)80013-6.Full Text Link to Item
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Patel, D. D., and B. F. Haynes. “Leukocyte homing to synovium.” Curr Dir Autoimmun 3 (2001): 133–67. https://doi.org/10.1159/000060517.Full Text Link to Item
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Sundy, J. S., and B. F. Haynes. “Cytokines and adhesion molecules in the pathogenesis of vasculitis.” Curr Rheumatol Rep 2, no. 5 (October 2000): 402–10. https://doi.org/10.1007/s11926-000-0040-8.Full Text Link to Item
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Liao, H. X., D. C. Montefiori, D. D. Patel, D. M. Lee, W. K. Scott, M. Pericak-Vance, and B. F. Haynes. “Linkage of the CCR5 Delta 32 mutation with a functional polymorphism of CD45RA.” J Immunol 165, no. 1 (July 1, 2000): 148–57. https://doi.org/10.4049/jimmunol.165.1.148.Full Text Link to Item
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Patel, D. D., M. E. Gooding, R. E. Parrott, K. M. Curtis, B. F. Haynes, and R. H. Buckley. “Thymic function after hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency.” N Engl J Med 342, no. 18 (May 4, 2000): 1325–32. https://doi.org/10.1056/NEJM200005043421804.Full Text Link to Item
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Sempowski, G., J. Thomasch, M. Gooding, L. Hale, L. Edwards, E. Ciafaloni, D. Sanders, et al. “Effect of thymectomy on human peripheral T cell pools.” Faseb Journal 14, no. 6 (April 20, 2000): A1223–A1223.Link to Item
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Sempowski, G., M. Gooding, R. Scearce, and B. Haynes. “Role of leukemia inhibitory factor-induced corticosteroids in the pathogenesis of acute thymic atrophy.” Faseb Journal 14, no. 6 (April 20, 2000): A921–A921.Link to Item
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Markert, M. L., C. B. Hicks, J. A. Bartlett, J. L. Harmon, L. P. Hale, M. L. Greenberg, G. Ferrari, et al. “Effect of highly active antiretroviral therapy and thymic transplantation on immunoreconstitution in HIV infection.” Aids Res Hum Retroviruses 16, no. 5 (March 20, 2000): 403–13. https://doi.org/10.1089/088922200309061.Full Text Link to Item
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Sempowski, G. D., L. P. Hale, J. S. Sundy, J. M. Massey, R. A. Koup, D. C. Douek, D. D. Patel, and B. F. Haynes. “Leukemia inhibitory factor, oncostatin M, IL-6, and stem cell factor mRNA expression in human thymus increases with age and is associated with thymic atrophy.” J Immunol 164, no. 4 (February 15, 2000): 2180–87. https://doi.org/10.4049/jimmunol.164.4.2180.Full Text Link to Item
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Haynes, B. F., H. X. Liao, H. F. Staats, M. S. Alam, K. J. Weinhold, and D. C. Montefiori. “HIV vaccine development at Duke University Medical Center.” Immunol Res 22, no. 2–3 (2000): 263–69. https://doi.org/10.1385/ir:22:2-3:263.Full Text Link to Item
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Liao, H. X., B. Etemad-Moghadam, D. C. Montefiori, Y. Sun, J. Sodroski, R. M. Scearce, R. W. Doms, et al. “Induction of antibodies in guinea pigs and rhesus monkeys against the human immunodeficiency virus type 1 envelope: neutralization of nonpathogenic and pathogenic primary isolate simian/human immunodeficiency virus strains.” J Virol 74, no. 1 (January 2000): 254–63. https://doi.org/10.1128/jvi.74.1.254-263.2000.Full Text Link to Item
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Haynes, B. F., G. D. Sempowski, A. F. Wells, and L. P. Hale. “The human thymus during aging.” Immunol Res 22, no. 2–3 (2000): 253–61. https://doi.org/10.1385/IR:22:2-3:253.Full Text Link to Item
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Haynes, B. F., M. L. Markert, G. D. Sempowski, D. D. Patel, and L. P. Hale. “The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infection.” Annu Rev Immunol 18 (2000): 529–60. https://doi.org/10.1146/annurev.immunol.18.1.529.Full Text Link to Item
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PATEL, D. “784 Thymic output after non-ablative allogeneic hematopoietic stem cell transplantation in infants with severe combined immunodeficiency (SCID).” Journal of Allergy and Clinical Immunology 105, no. 1 (January 2000): S264–65. https://doi.org/10.1016/s0091-6749(00)91212-0.Full Text
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Markert, M. L., A. Boeck, L. P. Hale, A. L. Kloster, T. M. McLaughlin, M. N. Batchvarova, D. C. Douek, et al. “Transplantation of thymus tissue in complete DiGeorge syndrome.” N Engl J Med 341, no. 16 (October 14, 1999): 1180–89. https://doi.org/10.1056/NEJM199910143411603.Full Text Link to Item
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Flores, K. G., J. Li, G. D. Sempowski, B. F. Haynes, and L. P. Hale. “Analysis of the human thymic perivascular space during aging.” J Clin Invest 104, no. 8 (October 1999): 1031–39. https://doi.org/10.1172/JCI7558.Full Text Link to Item
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Haynes, B. F. “HIV infection and the dynamic interplay between the thymus and the peripheral T cell pool.” Clin Immunol 92, no. 1 (July 1999): 3–5. https://doi.org/10.1006/clim.1999.4738.Full Text Link to Item
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Levesque, M. C., and B. F. Haynes. “TNFalpha and IL-4 regulation of hyaluronan binding to monocyte CD44 involves posttranslational modification of CD44.” Cell Immunol 193, no. 2 (May 1, 1999): 209–18. https://doi.org/10.1006/cimm.1999.1456.Full Text Link to Item
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Fong, A. M., B. F. Haynes, and D. D. Patel. “Molecular analysis of ALCAM (CD166) mediated homophilic cell adhesion.” Journal of Investigative Medicine 47, no. 4 (April 1, 1999): 189A-189A.Link to Item
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Haynes, B. F., and L. P. Hale. “Thymic function, aging, and AIDS.” Hosp Pract (1995) 34, no. 3 (March 15, 1999): 59-passim. https://doi.org/10.3810/hp.1999.03.134.Full Text Link to Item
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Sempowski, G., D. Lee, R. Scearce, D. Patel, and B. Haynes. “CD7 deficient mice are resistant to LPS-induced death and have diminished in vivo LPS-induced IFN-gamma and TNF-alpha production.” Faseb Journal 13, no. 5 (March 15, 1999): A1147–A1147.Link to Item
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Sempowski, G. D., D. M. Lee, R. M. Scearce, D. D. Patel, and B. F. Haynes. “Resistance of CD7-deficient mice to lipopolysaccharide-induced shock syndromes.” J Exp Med 189, no. 6 (March 15, 1999): 1011–16. https://doi.org/10.1084/jem.189.6.1011.Full Text Link to Item
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Fong, A. M., B. F. Haynes, and D. D. Patel. “Molecular analysis of ALCAM (CD166) mediated homophilic cell adhesion.” Faseb Journal 13, no. 4 (March 12, 1999): A626–A626.Link to Item
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Haynes, B. F., L. P. Hale, K. J. Weinhold, D. D. Patel, H. X. Liao, P. B. Bressler, D. M. Jones, et al. “Analysis of the adult thymus in reconstitution of T lymphocytes in HIV-1 infection.” J Clin Invest 103, no. 4 (February 1999): 453–60. https://doi.org/10.1172/JCI5201.Full Text Link to Item
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Haynes, B. F. “Milestones for training safe doctors who are good doctors.” Pharos Alpha Omega Alpha Honor Med Soc 62, no. 3 (1999): 30–33.Link to Item
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Haynes, B. F. “14G8 anti-LSP-1.” Hybridoma 18, no. 2 (January 1, 1999): 214. https://doi.org/10.1089/hyb.1999.18.214.Full Text
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Haynes, B. F. “5E3 anti-LSP-1.” Hybridoma 18, no. 2 (January 1, 1999): 213. https://doi.org/10.1089/hyb.1999.18.213.Full Text
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Sempowski, G. D., D. M. Lee, R. E. Kaufman, and B. F. Haynes. “Structure and function of the CD7 molecule.” Crit Rev Immunol 19, no. 4 (1999): 331–48.Link to Item
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Vu, H. M., D. Myers, R. de Lorimier, T. J. Matthews, M. A. Moody, C. Heinly, J. V. Torres, B. F. Haynes, and L. Spicer. “Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120: relation to specificity of peptide-induced anti-HIV neutralizing antibodies.” J Virol 73, no. 1 (January 1999): 746–50. https://doi.org/10.1128/JVI.73.1.746-750.1999.Full Text Link to Item
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Douek, D. C., R. D. McFarland, P. H. Keiser, E. A. Gage, J. M. Massey, B. F. Haynes, M. A. Polis, et al. “Changes in thymic function with age and during the treatment of HIV infection.” Nature 396, no. 6712 (December 17, 1998): 690–95. https://doi.org/10.1038/25374.Full Text Link to Item
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Palker, T. J., A. M. Fong, R. M. Scearce, D. D. Patel, and B. F. Haynes. “Developmental regulation of lymphocyte-specific protein 1 (LSP1) expression in thymus during human T-cell maturation.” Hybridoma 17, no. 6 (December 1998): 497–507. https://doi.org/10.1089/hyb.1998.17.497.Full Text Link to Item
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Patel, D. D., and B. F. Haynes. “New surrogate markers for autoimmune disease activity.” J Clin Invest 102, no. 6 (September 15, 1998): 1075–76. https://doi.org/10.1172/JCI4907.Full Text Link to Item
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Levesque, M. C., and B. F. Haynes. “T lymphocytes regulate hyaluronan binding to monocyte CD44 via a T lymphocyte-derived soluble factor and via monocyte-derived TNF alpha.” Arthritis and Rheumatism 41, no. 9 (September 1, 1998): S189–S189.Link to Item
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Levesque, M. C., and B. F. Haynes. “TNF alpha and IL-4 regulation of hyaluronan binding to monocyte CD44 involves post-translational modification of CD44.” Arthritis and Rheumatism 41, no. 9 (September 1, 1998): S189–S189.Link to Item
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Liao, H. X., J. R. Thomasch, and B. F. Haynes. “Induction of hyaluronan binding to immune cells in CD44 deficient mice that selectively express CD44S or CD44V isoforms.” Arthritis and Rheumatism 41, no. 9 (September 1, 1998): S190–S190.Link to Item
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Bartlett, J. A., S. S. Wasserman, C. B. Hicks, R. T. Dodge, K. J. Weinhold, C. O. Tacket, N. Ketter, A. E. Wittek, T. J. Palker, and B. F. Haynes. “Safety and immunogenicity of an HLA-based HIV envelope polyvalent synthetic peptide immunogen. DATRI 010 Study Group. Division of AIDS Treatment Research Initiative.” Aids 12, no. 11 (July 30, 1998): 1291–1300. https://doi.org/10.1097/00002030-199811000-00010.Full Text Link to Item
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Lee, D. M., H. F. Staats, J. S. Sundy, D. D. Patel, G. D. Sempowski, R. M. Scearce, D. M. Jones, and B. F. Haynes. “Immunologic characterization of CD7-deficient mice.” J Immunol 160, no. 12 (June 15, 1998): 5749–56.Link to Item
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Miralles, G. D., C. A. Smith, L. P. Whichard, M. A. Morse, B. F. Haynes, and D. D. Patel. “CD34+CD38-lin- cord blood cells develop into dendritic cells in human thymic stromal monolayers and thymic nodules.” J Immunol 160, no. 7 (April 1, 1998): 3290–98.Link to Item
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Haynes, B. F., and L. P. Hale. “The human thymus. A chimeric organ comprised of central and peripheral lymphoid components.” Immunol Res 18, no. 2 (1998): 61–78. https://doi.org/10.1007/BF02788750.Full Text Link to Item
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Haynes, B. F., and L. P. Hale. “The human thymus. A chimeric organ comprised of central and peripheral lymphoid components.” Immunol Res 18, no. 3 (1998): 175–92. https://doi.org/10.1007/BF02788778.Full Text Link to Item
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Levesque, M. C., and B. F. Haynes. “Cytokine induction of the ability of human monocyte CD44 to bind hyaluronan is mediated primarily by TNF-alpha and is inhibited by IL-4 and IL-13.” J Immunol 159, no. 12 (December 15, 1997): 6184–94.Link to Item
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Aruffo, A., M. A. Bowen, D. D. Patel, B. F. Haynes, G. C. Starling, J. A. Gebe, and J. Bajorath. “CD6-ligand interactions: a paradigm for SRCR domain function?” Immunol Today 18, no. 10 (October 1997): 498–504. https://doi.org/10.1016/s0167-5699(97)01130-4.Full Text Link to Item
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Weinberg, J., H. X. Liao, J. V. Torres, T. J. Matthews, J. Robinson, and B. F. Haynes. “Identification of a synthetic peptide that mimics an HIV glycoprotein 120 envelope conformational determinant exposed following ligation of glycoprotein 120 by CD4.” Aids Res Hum Retroviruses 13, no. 8 (May 20, 1997): 657–64. https://doi.org/10.1089/aid.1997.13.657.Full Text Link to Item
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Davis, C. M., T. M. McLaughlin, T. J. Watson, R. H. Buckley, S. E. Schiff, L. P. Hale, B. F. Haynes, and M. L. Markert. “Normalization of the peripheral blood T cell receptor V beta repertoire after cultured postnatal human thymic transplantation in DiGeorge syndrome.” J Clin Immunol 17, no. 2 (March 1997): 167–75. https://doi.org/10.1023/a:1027382600143.Full Text Link to Item
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Krowka, J. F., H. W. Sheppard, and M. S. Ascher. “Immunotherapy for HIV.” Lancet 349, no. 9049 (February 8, 1997): 434. https://doi.org/10.1016/S0140-6736(97)80060-8.Full Text Link to Item
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Haynes, Barton F. “Immunotherapy for HIV.” The Lancet 349, no. 9049 (February 1997): 434–434. https://doi.org/10.1016/s0140-6736(05)65060-x.Full Text
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Markert, M. L., D. D. Kostyu, F. E. Ward, T. M. McLaughlin, T. J. Watson, R. H. Buckley, S. E. Schiff, et al. “Successful formation of a chimeric human thymus allograft following transplantation of cultured postnatal human thymus.” J Immunol 158, no. 2 (January 15, 1997): 998–1005.Link to Item
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Haynes, B. F. “Mentoring physician-scientists: fear of the unknown and scientific opportunity.” Pharos Alpha Omega Alpha Honor Med Soc 60, no. 3 (1997): 10–12.Link to Item
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Haynes, B. F. “Department of error: (New frontiers of immunotherapy for HIV, December 7 (1531)).” Lancet 349, no. 9050 (January 1, 1997): 510. https://doi.org/10.1016/s0140-6736(05)61233-0.Full Text
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Patel, D. D., L. P. Whichard, G. D. Miralles, J. S. Sundy, and B. F. Haynes. “In vitro formation of the human thymic microenvironment: Similarity to SCID thymus.” Journal of Allergy and Clinical Immunology 99, no. 1 (January 1, 1997): 1602–1602.Link to Item
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Snyderman, R., and B. F. Haynes. “Advances in rheumatology - Preface.” Medical Clinics of North America 81, no. 1 (January 1, 1997): U3–U3.Link to Item
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Markert, M. L., T. J. Watson, I. Kaplan, L. P. Hale, and B. F. Haynes. “The human thymic microenvironment during organ culture.” Clin Immunol Immunopathol 82, no. 1 (January 1997): 26–36. https://doi.org/10.1006/clin.1996.4266.Full Text Link to Item
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McCallum, R. M., D. D. Patel, J. O. Moore, and B. F. Haynes. “Arthritis syndromes associated with human T cell lymphotropic virus type I infection.” Med Clin North Am 81, no. 1 (January 1997): 261–76. https://doi.org/10.1016/s0025-7125(05)70514-9.Full Text Link to Item
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Haynes, B. F. “New frontiers of immunotherapy for HIV.” Lancet 348, no. 9041 (December 7, 1996): 1531–32. https://doi.org/10.1016/S0140-6736(05)66165-X.Full Text Link to Item
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Haynes, B. F. “HIV vaccines: where we are and where we are going.” Lancet 348, no. 9032 (October 5, 1996): 933–37. https://doi.org/10.1016/S0140-6736(96)09339-7.Full Text Link to Item
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Lee, D. M., D. D. Patel, and B. F. Haynes. “Study of the effects of CD7 monoclonal antibodies on proliferative responses and cytokine production of human PBMC.” Tissue Antigens 48, no. 4–II (October 1, 1996): TC108–TC108.Link to Item
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Liao, H. X., and B. F. Haynes. “Ability of CD44 Mabs to modulate hyaluronan binding to CD44-transfected Jurkat T cells.” Tissue Antigens 48, no. 4–II (October 1, 1996): AS206–AS206.Link to Item
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Patel, D. D., L. P. Whichard, A. M. Fong, and B. F. Haynes. “Tissue distribution and functional evaluation of antibodies A029, A030 and A109, reactive with ALCAM, a ligand for CD6.” Tissue Antigens 48, no. 4–II (October 1, 1996): AS402–AS402.Link to Item
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Levesque, M. C., and B. F. Haynes. “Regulation of hyaluronan binding to monocyte CD44 by cytokines and lipopolysaccharide.” Arthritis and Rheumatism 39, no. 9 (September 1, 1996): 53–53.Link to Item
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Lee, D. M., D. D. Patel, A. M. Pendergast, and B. F. Haynes. “Functional association of CD7 with phosphatidylinositol 3-kinase: interaction via a YEDM motif.” Int Immunol 8, no. 8 (August 1996): 1195–1203. https://doi.org/10.1093/intimm/8.8.1195.Full Text Link to Item
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Haynes, B. F., G. Pantaleo, and A. S. Fauci. “Response: HIV Quasispecies and Resampling.” Science 273, no. 5274 (July 26, 1996): 416a. https://doi.org/10.1126/science.273.5274.416a.Full Text Link to Item
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Haynes, B. F., G. Pantaleo, and A. S. Fauci. “HIV quasispecies and resampling - Response.” Science 273, no. 5274 (July 26, 1996): 416–416.Link to Item
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Liu, S. L., A. G. Rodrigo, R. Shankarappa, G. H. Learn, L. Hsu, O. Davidov, L. P. Zhao, and J. I. Mullins. “HIV quasispecies and resampling.” Science 273, no. 5274 (July 26, 1996): 415–16. https://doi.org/10.1126/science.273.5274.415.Full Text Link to Item
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Haynes, B. F., G. Pantaleo, and A. S. Fauci. “Response: Correlates of Protective Viruses Damaging to HIV Infection.” Science 272, no. 5266 (May 31, 1996): 1362b. https://doi.org/10.1126/science.272.5266.1362b.Full Text Link to Item
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Zinkernagel, R. M., and H. Hengartner. “Correlates of protective viruses damaging to HIV infection.” Science 272, no. 5266 (May 31, 1996): 1362.Link to Item
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Taylor, G. A., E. Carballo, D. M. Lee, W. S. Lai, M. J. Thompson, D. D. Patel, D. I. Schenkman, et al. “A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency.” Immunity 4, no. 5 (May 1996): 445–54. https://doi.org/10.1016/s1074-7613(00)80411-2.Full Text Link to Item
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Markert, M. L., C. M. Davis, F. E. Ward, D. D. Kostyu, R. H. Buckley, S. E. Schiff, T. J. Watson, et al. “Thymic transplantation for digeorge syndrome.” Faseb Journal 10, no. 6 (April 30, 1996): 373–373.Link to Item
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Vu, H. M., R. de Lorimier, M. A. Moody, B. F. Haynes, and L. D. Spicer. “Conformational preferences of a chimeric peptide HIV-1 immunogen from the C4-V3 domains of gp120 envelope protein of HIV-1 CAN0A based on solution NMR: comparison to a related immunogenic peptide from HIV-1 RF.” Biochemistry 35, no. 16 (April 23, 1996): 5158–65. https://doi.org/10.1021/bi952665x.Full Text Link to Item
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Fox, C. H. “HIV viral load assay.” Science 271, no. 5252 (February 23, 1996): 1043.Link to Item
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Haynes, B. F. “Response: HIV Viral Load Assay.” Science 271, no. 5252 (February 23, 1996): 1043b. https://doi.org/10.1126/science.271.5252.1043b.Full Text Link to Item
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Haynes, B. F. “HIV viral load assay - Reply.” Science 271, no. 5252 (February 23, 1996): 1043–1043.Link to Item
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Levesque, M. C., and B. F. Haynes. “In vitro culture of human peripheral blood monocytes induces hyaluronan binding and up-regulates monocyte variant CD44 isoform expression.” J Immunol 156, no. 4 (February 15, 1996): 1557–65.Link to Item
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Haynes, B. F., S. B. Putman, and J. B. Weinberg. “Update on the issues of HIV vaccine development.” Ann Med 28, no. 1 (February 1996): 39–41. https://doi.org/10.3109/07853899608999072.Full Text Link to Item
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Haynes, B. F., G. Pantaleo, and A. S. Fauci. “Toward an understanding of the correlates of protective immunity to HIV infection.” Science 271, no. 5247 (January 19, 1996): 324–28. https://doi.org/10.1126/science.271.5247.324.Full Text Link to Item
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Lee, D. M., J. S. Sundy, H. F. Staats, D. D. Patel, and B. F. Haynes. “Initial characterization of cd7 deficient mice: evidence of a role for CD7 in regulation of thymocyte development.” Journal of Investigative Medicine 44, no. 3 (January 1, 1996).
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Patel, D. D., C. S. Heinly, L. P. Whichard, and B. F. Haynes. “Regulated expression of activated leukocyte cell adhesion molecule, a ligand for cd6, in rheumatoid arthritis synovium.” Journal of Investigative Medicine 44, no. 3 (January 1, 1996).
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Sundv, J. S., T. S. Barry, D. D. Patel, N. B. Allen, B. Devlin, S. Bigner, R. E. Kaufman, and B. F. Haynes. “Myotropic Th1 T helper cell lymphoma presenting as granulomatous inflammatory masses in synovium and muscle.” Journal of Investigative Medicine 44, no. 3 (January 1, 1996).
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Sundy, J. S., D. D. Patel, L. P. Whichard, P. J. Lager, and B. F. Haynes. “Constitutive cytokine mRNA production in human post-natal thymus: RT-PCR analysis of cellular subsets.” Journal of Allergy and Clinical Immunology 97, no. 1 (January 1, 1996): 975–975.Link to Item
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Lee, D. M., L. E. Schanberg, D. E. Fleenor, M. F. Seldin, B. F. Haynes, and R. E. Kaufman. “The mouse CD7 gene: identification of a new element common to the human CD7 and mouse Thy-1 promoters.” Immunogenetics 44, no. 2 (1996): 108–14.Link to Item
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Hale, L. P., D. D. Patel, R. E. Clark, and B. F. Haynes. “Distribution of CD44 variant isoforms in human skin: differential expression in components of benign and malignant epithelia.” J Cutan Pathol 22, no. 6 (December 1995): 536–45. https://doi.org/10.1111/j.1600-0560.1995.tb01148.x.Full Text Link to Item
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Hale, L. P., B. F. Haynes, and S. S. McCachren. “Expression of CD44 variants in human inflammatory synovitis.” J Clin Immunol 15, no. 6 (November 1995): 300–311. https://doi.org/10.1007/BF01541320.Full Text Link to Item
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Sundy, J. S., and B. F. Haynes. “Pathogenic mechanisms of vessel damage in vasculitis syndromes.” Rheum Dis Clin North Am 21, no. 4 (November 1995): 861–81.Link to Item
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Liao, H. X., D. M. Lee, M. C. Levesque, and B. F. Haynes. “N-terminal and central regions of the human CD44 extracellular domain participate in cell surface hyaluronan binding.” J Immunol 155, no. 8 (October 15, 1995): 3938–45.Link to Item
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MARKERT, M. L., T. J. WATSON, T. M. MCLAUGHLIN, C. A. MCGUIRE, F. E. WARD, D. KOSTYU, L. P. HALE, et al. “DEVELOPMENT OF T-CELL FUNCTION AFTER POSTNATAL THYMIC TRANSPLANTATION FOR DIGEORGE-SYNDROME.” American Journal of Human Genetics 57, no. 4 (October 1, 1995): 64–64.Link to Item
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Schanberg, L. E., D. M. Lee, D. E. Fleenor, R. E. Ware, D. D. Patel, B. F. Haynes, and R. E. Kaufman. “Characterization of human CD7 transgenic mice.” J Immunol 155, no. 5 (September 1, 1995): 2407–18.Link to Item
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Liao, H. X., and B. F. Haynes. “Role of adhesion molecules in the pathogenesis of rheumatoid arthritis.” Rheum Dis Clin North Am 21, no. 3 (August 1995): 715–40.Link to Item
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Dukes, C. S., Y. Yu, E. D. Rivadeneira, D. L. Sauls, H. X. Liao, B. F. Haynes, and J. B. Weinberg. “Cellular CD44S as a determinant of human immunodeficiency virus type 1 infection and cellular tropism.” J Virol 69, no. 7 (July 1995): 4000–4005. https://doi.org/10.1128/JVI.69.7.4000-4005.1995.Full Text Link to Item
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Bowen, M. A., D. D. Patel, X. Li, B. Modrell, A. R. Malacko, W. C. Wang, H. Marquardt, M. Neubauer, J. M. Pesando, and U. Francke. “Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand.” J Exp Med 181, no. 6 (June 1, 1995): 2213–20. https://doi.org/10.1084/jem.181.6.2213.Full Text Link to Item
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Rivadeneira, E. D., D. L. Sauls, Y. Yu, B. F. Haynes, and J. B. Weinberg. “Inhibition of HIV type 1 infection of mononuclear phagocytes by anti-CD44 antibodies.” Aids Res Hum Retroviruses 11, no. 5 (May 1995): 541–46. https://doi.org/10.1089/aid.1995.11.541.Full Text Link to Item
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SPICER, L. D., H. VU, R. DELORIMIER, M. A. MOODY, and B. F. HAYNES. “NMR CONFORMATIONAL STUDIES BY IMMUNOGENIC PEPTIDE-FRAGMENTS DERIVED FROM HIV COAT PROTEIN-GP120.” Journal of Cellular Biochemistry, April 2, 1995, 50–50.Link to Item
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Haynes, B. F., and C. S. Heinly. “Early human T cell development: analysis of the human thymus at the time of initial entry of hematopoietic stem cells into the fetal thymic microenvironment.” J Exp Med 181, no. 4 (April 1, 1995): 1445–58. https://doi.org/10.1084/jem.181.4.1445.Full Text Link to Item
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Patel, D. D., S. F. Wee, L. P. Whichard, M. A. Bowen, J. M. Pesando, A. Aruffo, and B. F. Haynes. “Identification and characterization of a 100-kD ligand for CD6 on human thymic epithelial cells.” J Exp Med 181, no. 4 (April 1, 1995): 1563–68. https://doi.org/10.1084/jem.181.4.1563.Full Text Link to Item
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MARKERT, M. L., F. E. WARD, D. KOSTYU, R. H. BUCKLEY, S. E. SCHIFF, J. J. H. BLEESING, C. B. BROOME, et al. “DEVELOPMENT OF T-CELL FUNCTION AFTER POSTNATAL THYMIC TRANSPLANTATION FOR DIGEORGE-SYNDROME.” Faseb Journal 9, no. 4 (March 10, 1995): A780–A780.Link to Item
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WEE, S. F., L. P. WHICHARD, M. A. BOWEN, J. M. PESANDO, A. ARUFFO, and B. F. HAYNES. “IDENTIFICATION AND CHARACTERIZATION OF A LIGAND FOR CD6 ON HUMAN THYMIC EPITHELIAL-CELLS THAT MEDIATES THYMOCYTE-THYMIC EPITHELIAL-CELL INTERACTIONS.” Faseb Journal 9, no. 4 (March 10, 1995): A778–A778.Link to Item
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LEE, D. M., M. F. SELDIN, R. E. KAUFMAN, and B. F. HAYNES. “GENETIC AND BIOCHEMICAL-CHARACTERIZATION OF MOUSE CD7 - IDENTIFICATION OF A NOVEL PROMOTER SEQUENCE.” Faseb Journal 9, no. 3 (March 9, 1995): A233–A233.Link to Item
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Bruggers, C. S., D. D. Patel, R. M. Scearce, L. P. Whichard, B. F. Haynes, and K. H. Singer. “AD2, a human molecule involved in the interaction of T cells with epidermal keratinocytes and thymic epithelial cells.” J Immunol 154, no. 5 (March 1, 1995): 2012–22.Link to Item
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Patel, D. D., L. P. Whichard, G. Radcliff, S. M. Denning, and B. F. Haynes. “Characterization of human thymic epithelial cell surface antigens: phenotypic similarity of thymic epithelial cells to epidermal keratinocytes.” J Clin Immunol 15, no. 2 (March 1995): 80–92. https://doi.org/10.1007/BF01541736.Full Text Link to Item
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Haynes, B. F., M. A. Moody, C. S. Heinley, B. Korber, W. A. Millard, and R. M. Scearce. “HIV type 1 V3 region primer-induced antibody suppression is overcome by administration of C4-V3 peptides as a polyvalent immunogen.” Aids Res Hum Retroviruses 11, no. 2 (February 1995): 211–21. https://doi.org/10.1089/aid.1995.11.211.Full Text Link to Item
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Patel, D. D., L. P. Hale, L. P. Whichard, G. Radcliff, C. R. Mackay, and B. F. Haynes. “Expression of CD44 molecules and CD44 ligands during human thymic fetal development: expression of CD44 isoforms is developmentally regulated.” Int Immunol 7, no. 2 (February 1995): 277–86. https://doi.org/10.1093/intimm/7.2.277.Full Text Link to Item
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Hart, M. K., T. J. Palker, and B. F. Haynes. “Design of experimental synthetic peptide immunogens for prevention of HIV-1 and HTLV-I retroviral infections.” Pharm Biotechnol 6 (1995): 821–45. https://doi.org/10.1007/978-1-4615-1823-5_37.Full Text Link to Item
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Klinman, D. M., B. F. Haynes, and J. Conover. “Activation of interleukin 4- and interleukin 6-secreting cells by HIV-specific synthetic peptides.” Aids Res Hum Retroviruses 11, no. 1 (January 1995): 97–105. https://doi.org/10.1089/aid.1995.11.97.Full Text Link to Item
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Wee, S., W. C. Wang, A. G. Farr, A. J. Nelson, D. D. Patel, B. F. Haynes, P. S. Linsley, and A. Aruffo. “Characterization of a CD6 ligand(s) expressed on human- and murine-derived cell lines and murine lymphoid tissues.” Cell Immunol 158, no. 2 (October 15, 1994): 353–64. https://doi.org/10.1006/cimm.1994.1282.Full Text Link to Item
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deCastro, C. M., S. M. Denning, S. Langdon, G. R. Vandenbark, J. Kurtzberg, R. Scearce, B. F. Haynes, and R. E. Kaufman. “The c-kit proto-oncogene receptor is expressed on a subset of human CD3-CD4-CD8- (triple-negative) thymocytes.” Exp Hematol 22, no. 10 (September 1994): 1025–33.Link to Item
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Hardy, L. M., B. F. Haynes, and P. A. Volberding. “From the Institute of Medicine.” Jama 272, no. 6 (August 10, 1994): 423. https://doi.org/10.1001/jama.272.6.423.Full Text Link to Item
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WINCHELL, J. M., L. K. SILBART, T. J. PALKER, J. D. CLEMENTS, P. W. BETTS, and B. F. HAYNES. “PRODUCTION OF IMMUNOGENS TO ELICIT AN ANTI-HIV MUCOSAL IMMUNE-RESPONSE.” Faseb Journal 8, no. 5 (March 18, 1994): A961–A961.Link to Item
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Lorimier, R. de, M. A. Moody, B. F. Haynes, and L. D. Spicer. “NMR-derived solution conformations of a hybrid synthetic peptide containing multiple epitopes of envelope protein gp120 from the RF strain of human immunodeficiency virus.” Biochemistry 33, no. 8 (March 1, 1994): 2055–62. https://doi.org/10.1021/bi00174a011.Full Text Link to Item
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MYERS, D., M. A. MOODY, B. F. HAYNES, and L. D. SPICER. “THE 2-D NMR CHARACTERIZATION OF A 39 RESIDUE IMMUNOGENIC CHIMERIC PEPTIDE DERIVED FROM HIVMN.” Biophysical Journal 66, no. 2 (February 1, 1994): A29–A29.Link to Item
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Patel, D. D., and B. F. Haynes. “Stage-specific adhesion molecules in human intrathymic T-cell development.” Res Immunol 145, no. 2 (February 1994): 144–46. https://doi.org/10.1016/s0923-2494(94)80028-6.Full Text Link to Item
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Breit, T. M., J. J. M. Van Dongen, A. Barcena, M. D. Mossalayi, and B. F. Haynes. “Human early T-cell differentiation: Discussion.” Research in Immunology 145, no. 2 (January 1, 1994): 155–58.
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Rendt, K. E., T. S. Barry, D. M. Jones, C. B. Richter, S. S. McCachren, and B. F. Haynes. “Engraftment of human synovium into severe combined immune deficient mice. Migration of human peripheral blood T cells to engrafted human synovium and to mouse lymph nodes.” J Immunol 151, no. 12 (December 15, 1993): 7324–36.Link to Item
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Liao, H. X., M. C. Levesque, K. Patton, B. Bergamo, D. Jones, M. A. Moody, M. J. Telen, and B. F. Haynes. “Regulation of human CD44H and CD44E isoform binding to hyaluronan by phorbol myristate acetate and anti-CD44 monoclonal and polyclonal antibodies.” J Immunol 151, no. 11 (December 1, 1993): 6490–99.Link to Item
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DECASTRO, C. M., S. M. DENNING, S. LANGDON, J. KURTZBERG, R. SCEARCE, B. F. HAYNES, and R. E. KAUFMAN. “EXPRESSION OF C-KIT RECEPTORS AND KIT-LIGAND IN HUMAN THYMOCYTES AND THYMUS TISSUE.” Blood 82, no. 10 (November 15, 1993): A244–A244.Link to Item
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HALE, L. P., C. R. MCKAY, B. F. HAYNES, and S. S. MCCACHREN. “SYNOVIAL LINING MACROPHAGES IN RHEUMATOID-ARTHRITIS PREFERENTIALLY EXPRESS SPECIFIC CD44-VARIANT ISOFORMS COMPARED TO OTHER TISSUE MACROPHAGES.” Blood 82, no. 10 (November 15, 1993): A32–A32.Link to Item
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Yasutomi, Y., T. J. Palker, M. B. Gardner, B. F. Haynes, and N. L. Letvin. “Synthetic peptide in mineral oil adjuvant elicits simian immunodeficiency virus-specific CD8+ cytotoxic T lymphocytes in rhesus monkeys.” J Immunol 151, no. 9 (November 1, 1993): 5096–5105.Link to Item
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HAYNES, B. F., J. V. TORRES, A. J. LANGLOIS, D. P. BOLOGNESI, M. B. GARDNER, T. J. PALKER, R. M. SCEARCE, et al. “INDUCTION OF BROADLY CROSS-REACTIVE HIV NEUTRALIZING ANTIBODIES IN PRIMATES USING A PRIME-BOOST REGIMEN OF HYBRID SYNTHETIC GP120 ENVELOPE PEPTIDES.” Aids Research and Human Retroviruses 9 (October 1, 1993): S29–S29.Link to Item
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TELEN, M. J., N. RAO, M. UDANI, H. X. LIAO, and B. F. HAYNES. “RELATIONSHIP OF THE ANWJ BLOOD-GROUP ANTIGEN TO EXPRESSION OF CD-44.” Transfusion 33, no. 9 (September 1, 1993): S48–S48.Link to Item
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Haynes, B. F., J. V. Torres, A. J. Langlois, D. P. Bolognesi, M. B. Gardner, T. J. Palker, R. M. Scearce, D. M. Jones, M. A. Moody, and C. McDanal. “Induction of HIVMN neutralizing antibodies in primates using a prime-boost regimen of hybrid synthetic gp120 envelope peptides.” J Immunol 151, no. 3 (August 1, 1993): 1646–53.Link to Item
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Patel, D. D., and B. F. Haynes. “Cell adhesion molecules involved in intrathymic T cell development.” Semin Immunol 5, no. 4 (August 1993): 282–92. https://doi.org/10.1006/smim.1993.1032.Full Text Link to Item
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Haynes, B. F. “Scientific and social issues of human immunodeficiency virus vaccine development.” Science 260, no. 5112 (May 28, 1993): 1279–86. https://doi.org/10.1126/science.8493572.Full Text Link to Item
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HAYNES, B. F., Y. YASUTOMI, J. V. TORRES, M. B. GARDNER, A. J. LANGLOIS, D. P. BOLOGNESI, T. J. MATTHEWS, et al. “USE OF SYNTHETIC PEPTIDES IN PRIMATES TO INDUCE HIGH-TITERED NEUTRALIZING ANTIBODIES AND MHC CLASS I-RESTRICTED CYTOTOXIC T-CELLS AGAINST AIDS RETROVIRUSES - AN HLA-BASED VACCINE STRATEGY.” Clinical Research 41, no. 2 (April 1, 1993): A261–A261.Link to Item
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LIAO, H. X., M. C. LEVESQUE, K. PATTON, B. BERGAMO, D. JONES, M. A. MOODY, and B. F. HAYNES. “REGULATION OF HUMAN CD44H AND CD44E ISOFORM BINDING TO HYALLURONAN BY PHORBOL-MYRISTATE ACETATE AND ANTI-CD44 MONOCLONAL AND POLYCLONAL ANTIBODIES.” Clinical Research 41, no. 2 (April 1, 1993): A169–A169.Link to Item
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PATEL, D. D., S. F. WEE, K. H. SINGER, L. W. VOLLGER, B. F. HAYNES, and A. ARUFFO. “HUMAN THYMIC EPITHELIAL-CELLS EXPRESS A LIGAND FOR CD6 WHICH MEDIATES BINDING TO MATURE THYMOCYTES.” Clinical Research 41, no. 2 (April 1, 1993): A220–A220.Link to Item
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RIVADENEIRA, E. D., H. X. LIAO, D. L. SAULS, B. F. HAYNES, and J. B. WEINBERG. “DIFFERENTIAL MODULATION OF HIV-1 INFECTION OF A T-CELL LINE BY EXPRESSION OF TRANSFECTED CD44E AND CD44H ISOFORMS.” Clinical Research 41, no. 2 (April 1, 1993): A322–A322.Link to Item
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St Clair, E. W., and B. F. Haynes. “The future of rheumatoid arthritis treatment.” Bull Rheum Dis 42, no. 2 (April 1993): 1–4.Link to Item
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McCallum, R. M., L. M. Cobo, and B. F. Haynes. “Analysis of corneal and conjunctival microenvironments using monoclonal antibodies.” Invest Ophthalmol Vis Sci 34, no. 5 (April 1993): 1793–1803.Link to Item
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TELEN, M. J., N. RAO, M. UDANI, H. X. LIAO, and B. F. HAYNES. “THE ANWJ BLOOD-GROUP ANTIGEN HAEMOPHILUS-INFLUENZAE RECEPTOR RESIDES ON A HIGH-MOLECULAR-WEIGHT PROTEIN EXPRESSED BY CD44 TRANSFECTANTS.” Clinical Research 41, no. 2 (April 1, 1993): A161–A161.Link to Item
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Haynes, B. F., L. O. Arthur, P. Frost, T. J. Matthews, A. J. Langlois, T. J. Palker, M. K. Hart, R. M. Scearce, D. M. Jones, and C. McDanal. “Conversion of an immunogenic human immunodeficiency virus (HIV) envelope synthetic peptide to a tolerogen in chimpanzees by the fusogenic domain of HIV gp41 envelope protein.” J Exp Med 177, no. 3 (March 1, 1993): 717–27. https://doi.org/10.1084/jem.177.3.717.Full Text Link to Item
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Ware, R. E., and B. F. Haynes. “T cell CD7 mRNA expression is regulated by both transcriptional and post-transcriptional mechanisms.” Int Immunol 5, no. 2 (February 1993): 179–87. https://doi.org/10.1093/intimm/5.2.179.Full Text Link to Item
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BARRY, T. S., K. E. RENDT, R. E. WARE, D. M. JONES, C. B. RICHER, and B. F. HAYNES. “T-CELL RECEPTOR-BETA CHAIN VARIABLE REGION REPERTOIRES OF HUMAN T-CELLS THAT MIGRATED TO HUMAN SYNOVIAL XENOGRAFTS IMPLANTED IN SEVERE COMBINED IMMUNE DEFICIENT (SCID) MICE.” Journal of Cellular Biochemistry, January 26, 1993, 136–136.Link to Item
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HAYNES, B. F., K. RENDT, D. JONES, C. RICHTER, S. MCCACHREN, and T. BARRY. “AN INVIVO MODEL OF HUMAN INFLAMMATORY SYNOVITIS - ENGRAFTMENT OF HUMAN SYNOVIUM INTO INTO SEVERE COMBINED IMMUNE DEFICIENT (SCID) MICE AND MIGRATION OF PERIPHERAL-BLOOD (PB) T-CELLS TO ENGRAFTED HUMAN SYNOVIUM.” Journal of Cellular Biochemistry, January 26, 1993, 126–126.Link to Item
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Haynes, B. F., Y. Yasutomi, J. V. Torres, M. B. Gardner, A. J. Langlios, D. P. Bolognesi, T. J. Matthews, R. M. Scearce, D. M. Jones, and M. A. Moody. “Use of synthetic peptides in primates to induce high-titered neutralizing antibodies and MHC class I-restricted cytotoxic T cells against acquired immunodeficiency syndrome retroviruses: an HLA-based vaccine strategy.” Trans Assoc Am Physicians 106 (1993): 33–41.Link to Item
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Hale, L. P., and B. F. Haynes. “Bromelain treatment of human T cells removes CD44, CD45RA, E2/MIC2, CD6, CD7, CD8, and Leu 8/LAM1 surface molecules and markedly enhances CD2-mediated T cell activation.” J Immunol 149, no. 12 (December 15, 1992): 3809–16.Link to Item
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Palker, T. J., E. R. Riggs, D. E. Spragion, A. J. Muir, R. M. Scearce, R. R. Randall, M. W. McAdams, A. McKnight, P. R. Clapham, and R. A. Weiss. “Mapping of homologous, amino-terminal neutralizing regions of human T-cell lymphotropic virus type I and II gp46 envelope glycoproteins.” J Virol 66, no. 10 (October 1992): 5879–89. https://doi.org/10.1128/JVI.66.10.5879-5889.1992.Full Text Link to Item
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BARRY, T. S., K. E. RENDT, D. M. JONES, R. E. WARE, C. B. RICHTER, S. S. MCCACHREN, B. DEVLIN, R. E. KAUFMAN, and B. F. HAYNES. “ENGRAFTMENT OF HUMAN SYNOVIUM INTO SEVERE COMBINED IMMUNE DEFICIENT (SCID) MICE - MIGRATION OF HUMAN PERIPHERAL-BLOOD T-CELLS TO ENGRAFTED HUMAN SYNOVIUM.” Arthritis and Rheumatism 35, no. 9 (September 1, 1992): S45–S45.Link to Item
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MCCALLUM, R. M., N. B. ALLEN, L. M. COBO, B. A. WEBER, and B. F. HAYNES. “COGAN SYNDROME - CLINICAL-FEATURES AND OUTCOMES.” Arthritis and Rheumatism 35, no. 9 (September 1, 1992): S51–S51.Link to Item
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Barry, T. S., and B. F. Haynes. “In vivo models of human lymphopoiesis and autoimmunity in severe combined immune deficient mice.” J Clin Immunol 12, no. 5 (September 1992): 311–24. https://doi.org/10.1007/BF00920788.Full Text Link to Item
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Korber, B., S. Wolinsky, B. Haynes, K. Kunstman, R. Levy, M. Furtado, P. Otto, and G. Myers. “HIV-1 intrapatient sequence diversity in the immunogenic V3 region.” Aids Res Hum Retroviruses 8, no. 8 (August 1992): 1461–65. https://doi.org/10.1089/aid.1992.8.1461.Full Text Link to Item
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Jacobs, M. R., and B. F. Haynes. “Increase in TCR gamma delta T lymphocytes in synovia from rheumatoid arthritis patients with active synovitis.” J Clin Immunol 12, no. 2 (March 1992): 130–38. https://doi.org/10.1007/BF00918143.Full Text Link to Item
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Schnittman, S. M., K. H. Singer, J. J. Greenhouse, S. K. Stanley, L. P. Whichard, P. T. Le, B. F. Haynes, and A. S. Fauci. “Erratum: Thymic microenvironment induces HIV expression: Physiologic secretion of IL-6 by thymic epithelial cells up-regulates virus expression in chronically infected cells (Journal of Immunology (October 15, 1991) 147 (2553-2558)).” Journal of Immunology 148, no. 3 (January 1, 1992): 981.
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Hart, M. K., K. J. Weinhold, R. M. Scearce, E. M. Washburn, C. A. Clark, T. J. Palker, and B. F. Haynes. “Priming of anti-human immunodeficiency virus (HIV) CD8+ cytotoxic T cells in vivo by carrier-free HIV synthetic peptides.” Proc Natl Acad Sci U S A 88, no. 21 (November 1, 1991): 9448–52. https://doi.org/10.1073/pnas.88.21.9448.Full Text Link to Item
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Le, P. T., S. Lazorick, L. P. Whichard, B. F. Haynes, and K. H. Singer. “Regulation of cytokine production in the human thymus: epidermal growth factor and transforming growth factor alpha regulate mRNA levels of interleukin 1 alpha (IL-1 alpha), IL-1 beta, and IL-6 in human thymic epithelial cells at a post-transcriptional level.” J Exp Med 174, no. 5 (November 1, 1991): 1147–57. https://doi.org/10.1084/jem.174.5.1147.Full Text Link to Item
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Haynes, B. F., L. P. Hale, K. L. Patton, M. E. Martin, and R. M. McCallum. “Measurement of an adhesion molecule as an indicator of inflammatory disease activity. Up-regulation of the receptor for hyaluronate (CD44) in rheumatoid arthritis.” Arthritis Rheum 34, no. 11 (November 1991): 1434–43. https://doi.org/10.1002/art.1780341115.Full Text Link to Item
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Schnittman, S. M., K. H. Singer, J. J. Greenhouse, S. K. Stanley, L. P. Whichard, P. T. Le, B. F. Haynes, and A. S. Fauci. “Thymic microenvironment induces HIV expression. Physiologic secretion of IL-6 by thymic epithelial cells up-regulates virus expression in chronically infected cells.” J Immunol 147, no. 8 (October 15, 1991): 2553–58.Link to Item
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Ware, R. E., M. K. Hart, and B. F. Haynes. “Induction of T cell CD7 gene transcription by nonmitogenic ionomycin-induced transmembrane calcium flux.” J Immunol 147, no. 8 (October 15, 1991): 2787–94.Link to Item
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Denning, S. M., D. M. Jones, R. E. Ware, K. J. Weinhold, M. B. Brenner, and B. F. Haynes. “Analysis of clones derived from human CD7+CD4-CD8-CD3- thymocytes.” Int Immunol 3, no. 10 (October 1991): 1015–24. https://doi.org/10.1093/intimm/3.10.1015.Full Text Link to Item
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Haynes, B. F., H. X. Liao, and K. L. Patton. “The transmembrane hyaluronate receptor (CD44): multiple functions, multiple forms.” Cancer Cells 3, no. 9 (September 1991): 347–50.Link to Item
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Fung, M. R., R. M. Scearce, J. A. Hoffman, N. J. Peffer, S. R. Hammes, J. B. Hosking, R. Schmandt, W. A. Kuziel, B. F. Haynes, and G. B. Mills. “A tyrosine kinase physically associates with the beta-subunit of the human IL-2 receptor.” J Immunol 147, no. 4 (August 15, 1991): 1253–60.Link to Item
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Pisetsky, D. S., B. F. Haynes, P. E. Lipsky, A. H. Kang, and A. E. Postlethwaite. “The specialized centers of research in rheumatoid arthritis. Recent progress and prospects for future advances.” Hum Immunol 31, no. 2 (June 1991): 148–51. https://doi.org/10.1016/0198-8859(91)90019-6.Full Text Link to Item
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Haynes, B. F. “The Duke University Arthritis Center.” N C Med J 52, no. 5 (May 1991): 191–95.Link to Item
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RIVADENEIRA, E. D., T. J. MATTHEWS, B. F. HAYNES, and J. B. WEINBERG. “POSSIBLE ROLE OF THE HYALURONATE RECEPTOR (CD44) IN THE INVITRO INFECTION OF HUMAN MONOCYTES WITH HIV-1.” Clinical Research 39, no. 2 (April 1, 1991): A382–A382.Link to Item
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SCHNITTMAN, S. M., K. H. SINGER, J. J. GREENHOUSE, S. K. STANLEY, L. P. WHICHARD, B. F. HAYNES, and A. S. FAUCI. “THE ROLE OF THE THYMIC MICROENVIRONMENT IN THE PATHOGENESIS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV 1).” Clinical Research 39, no. 2 (April 1, 1991): A220–A220.Link to Item
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DENNING, S. M., R. E. WARE, M. B. BRENNER, and B. F. HAYNES. “ANALYSIS OF CLONAL PROGENY OF HUMAN T-CELL PRECURSORS.” Faseb Journal 5, no. 6 (March 19, 1991): A1674–A1674.Link to Item
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BRUGGERS, C., R. M. SCEARCE, B. F. HAYNES, and K. H. SINGER. “A NOVEL ADHESION MOLECULE EXPRESSED ON HSB T-CELL ACUTE LYMPHOBLASTIC-LEUKEMIA CELLS MEDIATES HSB ADHESION TO EPIDERMAL-KERATINOCYTES (EK).” Faseb Journal 5, no. 5 (March 15, 1991): A962–A962.Link to Item
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LE, P. T., S. LAZORICK, L. P. WHICHARD, B. F. HAYNES, and K. H. SINGER. “EGF, TGFA AND EGF-R REGULATE TRANSCRIPT LEVELS OF IL1-ALPHA, IL1-BETA AND IL6 IN HUMAN THYMIC EPITHELIAL (TE) CELLS AT A POSTTRANSCRIPTIONAL LEVEL.” Faseb Journal 5, no. 5 (March 15, 1991): A976–A976.Link to Item
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WARE, R. E., and B. F. HAYNES. “CD7 IS A CALCIUM-INDUCIBLE GENE TRANSCRIBED IN THE IMMEDIATE STAGES OF T-CELL ACTIVATION.” Faseb Journal 5, no. 5 (March 15, 1991): A991–A991.Link to Item
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RENDT, K. E., T. S. BARRY, D. M. JONES, C. E. RICHTER, S. S. MCCACHREN, and B. F. HAYNES. “AN INVIVO MODEL OF HUMAN RHEUMATOID-ARTHRITIS (RA) USING RA SYNOVIUM ENGRAFTED INTO SEVERE COMBINED IMMUNE-DEFICIENT (SCID) MICE.” Faseb Journal 5, no. 4 (March 11, 1991): A607–A607.Link to Item
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Schanberg, L. E., D. E. Fleenor, J. Kurtzberg, B. F. Haynes, and R. E. Kaufman. “Isolation and characterization of the genomic human CD7 gene: structural similarity with the murine Thy-1 gene.” Proc Natl Acad Sci U S A 88, no. 2 (January 15, 1991): 603–7. https://doi.org/10.1073/pnas.88.2.603.Full Text Link to Item
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Denning, S. M., D. M. Jones, R. E. Ware, K. J. Weinhold, M. B. Brenner, and B. F. Haynes. “Analysis of clones derived from human CD7+CD4-CD8-CD3- thymocytes.” International Immunology 3, no. 10 (1991): 1015–24.
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Gardner, M. B., J. R. Carlson, M. Jennings, A. Rosenthal, A. Langlois, B. Haynes, D. Bolognesi, and T. J. Palker. “SIV vaccine protection of rhesus monkeys.” Biotechnol Ther 2, no. 1–2 (1991): 9–19.Link to Item
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Barry, T. S., D. M. Jones, C. B. Richter, and B. F. Haynes. “Successful engraftment of human postnatal thymus in severe combined immune deficient (SCID) mice: differential engraftment of thymic components with irradiation versus anti-asialo GM-1 immunosuppressive regimens.” J Exp Med 173, no. 1 (January 1, 1991): 167–80. https://doi.org/10.1084/jem.173.1.167.Full Text Link to Item
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Jarjour, W., L. A. Mizzen, W. J. Welch, S. Denning, M. Shaw, T. Mimura, B. F. Haynes, and J. B. Winfield. “Constitutive expression of a groEL-related protein on the surface of human gamma/delta cells.” J Exp Med 172, no. 6 (December 1, 1990): 1857–60. https://doi.org/10.1084/jem.172.6.1857.Full Text Link to Item
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Le, P. T., S. Lazorick, L. P. Whichard, Y. C. Yang, S. C. Clark, B. F. Haynes, and K. H. Singer. “Human thymic epithelial cells produce IL-6, granulocyte-monocyte-CSF, and leukemia inhibitory factor.” J Immunol 145, no. 10 (November 15, 1990): 3310–15.Link to Item
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Hart, M. K., T. J. Palker, T. J. Matthews, A. J. Langlois, N. W. Lerche, M. E. Martin, R. M. Scearce, C. McDanal, D. P. Bolognesi, and B. F. Haynes. “Synthetic peptides containing T and B cell epitopes from human immunodeficiency virus envelope gp120 induce anti-HIV proliferative responses and high titers of neutralizing antibodies in rhesus monkeys.” J Immunol 145, no. 8 (October 15, 1990): 2677–85.Link to Item
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Schnittman, S. M., S. M. Denning, J. J. Greenhouse, J. S. Justement, M. Baseler, J. Kurtzberg, B. F. Haynes, and A. S. Fauci. “Evidence for susceptibility of intrathymic T-cell precursors and their progeny carrying T-cell antigen receptor phenotypes TCR alpha beta + and TCR gamma delta + to human immunodeficiency virus infection: a mechanism for CD4+ (T4) lymphocyte depletion.” Proc Natl Acad Sci U S A 87, no. 19 (October 1990): 7727–31. https://doi.org/10.1073/pnas.87.19.7727.Full Text Link to Item
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Jung, L. K., B. F. Haynes, S. Nakamura, S. Pahwa, and S. M. Fu. “Expression of early activation antigen (CD69) during human thymic development.” Clin Exp Immunol 81, no. 3 (September 1990): 466–74. https://doi.org/10.1111/j.1365-2249.1990.tb05357.x.Full Text Link to Item
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Le, P. T., L. W. Vollger, B. F. Haynes, and K. H. Singer. “Ligand binding to the LFA-3 cell adhesion molecule induces IL-1 production by human thymic epithelial cells.” J Immunol 144, no. 12 (June 15, 1990): 4541–47.Link to Item
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Montgomery, R. B., J. Kurtzberg, A. Rhinehardt-Clark, A. Haleen, S. Ramakrishnan, G. A. Olsen, W. P. Peters, C. A. Smith, B. F. Haynes, and L. L. Houston. “Elimination of malignant clonogenic T cells from human bone marrow using chemoimmunoseparation with 2'-deoxycoformycin, deoxyadenosine and an immunotoxin.” Bone Marrow Transplant 5, no. 6 (June 1990): 395–402.Link to Item
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Singer, K. H., P. T. Le, S. M. Denning, L. P. Whichard, and B. F. Haynes. “The role of adhesion molecules in epithelial-T-cell interactions in thymus and skin.” J Invest Dermatol 94, no. 6 Suppl (June 1990): 85S-90S. https://doi.org/10.1111/1523-1747.ep12876038.Full Text Link to Item
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Singer, K. H., S. M. Denning, L. P. Whichard, and B. F. Haynes. “Thymocyte LFA-1 and thymic epithelial cell ICAM-1 molecules mediate binding of activated human thymocytes to thymic epithelial cells.” J Immunol 144, no. 8 (April 15, 1990): 2931–39.Link to Item
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BARRY, T. S., D. M. JONES, M. E. MARTIN, C. B. RICHTER, and B. F. HAYNES. “ESTABLISHMENT OF A MODEL OF HUMAN THYMIC FUNCTION INVIVO - ENGRAFTMENT OF POSTNATAL HUMAN THYMUS IN IMMUNE DEFICIENT SCID MICE.” Clinical Research 38, no. 2 (April 1, 1990): A278–A278.Link to Item
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DENNING, S. M., D. M. JONES, R. E. WARE, and B. F. HAYNES. “DEFINITION OF NEW STAGES OF HUMAN INTRATHYMIC T-CELL DEVELOPMENT BY ANALYSIS OF CLONAL PROGENY OF CD3-,CD4-,CD8-THYMOCYTES.” Clinical Research 38, no. 2 (April 1, 1990): A390–A390.Link to Item
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HART, M. K., T. J. PALKER, T. J. MATTHEWS, A. J. LANGLOIS, N. LERCHE, M. E. MARTIN, R. M. SCEARCE, C. MCDANAL, D. P. BOLOGNESI, and B. F. HAYNES. “SYNTHETIC PEPTIDES CONTAINING T-BELL AND B-CELL EPITOPES FROM HIV ENVELOPE GP120 INDUCE ANTI-HIV PROLIFERATIVE RESPONSES AND HIGH TITERS OF NEUTRALIZING ANTIBODIES IN RHESUS-MONKEYS.” Clinical Research 38, no. 2 (April 1, 1990): A279–A279.Link to Item
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LE, P. T., S. LAZORICK, L. P. WHICHARD, B. F. HAYNES, and K. H. SINGER. “REGULATION OF HUMAN THYMIC EPITHELIAL-CELL (TE) CYTOKINE PRODUCTION - EGF AND TGF-ALPHA INCREASE IL1-ALPHA, IL1-BETA, AND IL6 MESSENGER-RNA LEVELS IN CULTURED HUMAN TE CELLS.” Clinical Research 38, no. 2 (April 1, 1990): A479–A479.Link to Item
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PALKER, T. J., R. D. STREILEIN, R. M. SCEARCE, A. MCKNIGHT, P. CLAPHAM, R. A. WEISS, and B. F. HAYNES. “NEUTRALIZATION OF HUMAN T-CELL LEUKEMIA-VIRUS TYPE-I (HTLV-I) WITH ANTIPEPTIDE ANTISERA.” Clinical Research 38, no. 2 (April 1, 1990): A361–A361.Link to Item
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SCHNITTMAN, S. M., S. M. DENNING, J. J. GREENHOUSE, J. S. JUSTEMENT, M. BASELER, B. F. HAYNES, and A. S. FAUCI. “EVIDENCE FOR SUSCEPTIBILITY OF INTRATHYMIC T-CELL PRECURSORS TO HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION - A MECHANISM FOR LYMPHOCYTE-T4 DEPLETION.” Clinical Research 38, no. 2 (April 1, 1990): A359–A359.Link to Item
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Allen, N. B., C. C. Cox, M. Cobo, J. Kisslo, M. R. Jacobs, R. M. McCallum, and B. F. Haynes. “Use of immunosuppressive agents in the treatment of severe ocular and vascular manifestations of Cogan's syndrome.” Am J Med 88, no. 3 (March 1990): 296–301. https://doi.org/10.1016/0002-9343(90)90157-9.Full Text Link to Item
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Denning, S. M., P. T. Le, K. H. Singer, and B. F. Haynes. “Antibodies against the CD44 p80, lymphocyte homing receptor molecule augment human peripheral blood T cell activation.” J Immunol 144, no. 1 (January 1, 1990): 7–15.Link to Item
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HAYNES, B. F., M. K. HART, T. J. MATTHEWS, A. LANGLOIS, R. M. SCEARCE, M. E. MARTIN, N. LERCHE, J. A. BERZOFSKY, D. P. BOLOGNESI, and T. J. PALKER. “INDUCTION OF NEUTRALIZING ANTI-HIV ANTIBODIES IN GOATS AND RHESUS-MONKEYS WITH HYBRID SYNTHETIC PEPTIDES (T1-SP10) FROM HIV GP120 THAT CONTAIN EPITOPES RECOGNIZED BY BOTH T-CELLS AND B-CELLS.” Aids Research and Human Retroviruses 6, no. 1 (January 1, 1990): 38–39.Link to Item
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Haynes, B. F., S. M. Denning, P. T. Le, and K. H. Singer. “Human intrathymic T cell differentiation.” Semin Immunol 2, no. 1 (January 1990): 67–77.Link to Item
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Le, P. T., S. M. Denning, B. F. Haynes, and K. H. Singer. “Thymic epithelial-cell-derived cytokines and their roles in thymic precursor cell differentiation.” Research in Immunology 141, no. 3 (January 1, 1990): 271–75. https://doi.org/10.1016/0923-2494(90)90122-F.Full Text
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Schnittman, S. M., S. M. Denning, J. J. Greenhouse, J. S. Justement, M. Baseler, B. F. Haynes, and A. S. Fauci. “Evidence for susceptibility of intrathymic T cell precursors to human immunodeficiency virus infection: a mechanism for T4 (CD4) lymphocyte depletion.” Trans Assoc Am Physicians 103 (1990): 96–101.Link to Item
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Haynes, B. F. “Human thymic epithelium and T cell development: current issues and future directions.” Thymus 16, no. 3–4 (1990): 143–57.Link to Item
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McCachren, S. S., B. F. Haynes, and J. E. Niedel. “Localization of collagenase mRNA in rheumatoid arthritis synovium by in situ hybridization histochemistry.” J Clin Immunol 10, no. 1 (January 1990): 19–27. https://doi.org/10.1007/BF00917494.Full Text Link to Item
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Hale, L. P., K. H. Singer, and B. F. Haynes. “CD44 antibody against In(Lu)-related p80, lymphocyte-homing receptor molecule inhibits the binding of human erythrocytes to T cells.” J Immunol 143, no. 12 (December 15, 1989): 3944–48.Link to Item
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Begley, C. G., P. D. Aplan, S. M. Denning, B. F. Haynes, T. A. Waldmann, and I. R. Kirsch. “The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif.” Proc Natl Acad Sci U S A 86, no. 24 (December 1989): 10128–32. https://doi.org/10.1073/pnas.86.24.10128.Full Text Link to Item
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Ware, R. E., R. M. Scearce, M. A. Dietz, C. F. Starmer, T. J. Palker, and B. F. Haynes. “Characterization of the surface topography and putative tertiary structure of the human CD7 molecule.” J Immunol 143, no. 11 (December 1, 1989): 3632–40.Link to Item
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Haynes, B. F., M. J. Telen, L. P. Hale, and S. M. Denning. “CD44--a molecule involved in leukocyte adherence and T-cell activation.” Immunol Today 10, no. 12 (December 1989): 423–28. https://doi.org/10.1016/0167-5699(89)90040-6.Full Text Link to Item
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Kurtzberg, J., S. M. Denning, L. M. Nycum, K. H. Singer, and B. F. Haynes. “Immature human thymocytes can be driven to differentiate into nonlymphoid lineages by cytokines from thymic epithelial cells.” Proc Natl Acad Sci U S A 86, no. 19 (October 1989): 7575–79. https://doi.org/10.1073/pnas.86.19.7575.Full Text Link to Item
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Kurata, A., T. J. Palker, R. D. Streilein, R. M. Scearce, B. F. Haynes, and J. A. Berzofsky. “Immunodominant sites of human T cell lymphotropic virus type 1 envelope protein for murine helper T cells.” J Immunol 143, no. 6 (September 15, 1989): 2024–30.Link to Item
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Palker, T. J., T. J. Matthews, A. Langlois, M. E. Tanner, M. E. Martin, R. M. Scearce, J. E. Kim, J. A. Berzofsky, D. P. Bolognesi, and B. F. Haynes. “Polyvalent human immunodeficiency virus synthetic immunogen comprised of envelope gp120 T helper cell sites and B cell neutralization epitopes.” J Immunol 142, no. 10 (May 15, 1989): 3612–19.Link to Item
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Denning, S. M., J. Kurtzberg, D. S. Leslie, and B. F. Haynes. “Human postnatal CD4- CD8- CD3- thymic T cell precursors differentiate in vitro into T cell receptor delta-bearing cells.” J Immunol 142, no. 9 (May 1, 1989): 2988–97.Link to Item
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FUNG, M. R., R. M. SCEARCE, J. B. HOSKING, D. W. BALLARD, B. F. HAYNES, and W. C. GREENE. “ISOLATION OF MONOCLONAL-ANTIBODIES REACTIVE WITH THE 70-75 KD-BETA SUBUNIT OF THE HIGH-AFFINITY HUMAN INTERLEUKIN-2 RECEPTOR.” Clinical Research 37, no. 2 (April 1, 1989): A409–A409.Link to Item
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JUNG, L. K. L., B. F. HAYNES, S. PAHWA, and S. M. FU. “EXPRESSION OF EARLY ACTIVATION ANTIGEN, EA-1, ON HUMAN-FETAL AND POST-NATAL THYMUS.” Pediatric Research 25, no. 4 (April 1, 1989): A164–A164.Link to Item
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Picker, L. J., J. De los Toyos, M. J. Telen, B. F. Haynes, and E. C. Butcher. “Monoclonal antibodies against the CD44 [In(Lu)-related p80], and Pgp-1 antigens in man recognize the Hermes class of lymphocyte homing receptors.” J Immunol 142, no. 6 (March 15, 1989): 2046–51.Link to Item
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Begley, C. G., P. D. Aplan, M. P. Davey, K. Nakahara, K. Tchorz, J. Kurtzberg, M. S. Hershfield, B. F. Haynes, D. I. Cohen, and T. A. Waldmann. “Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript.” Proc Natl Acad Sci U S A 86, no. 6 (March 1989): 2031–35. https://doi.org/10.1073/pnas.86.6.2031.Full Text Link to Item
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Haynes, B. F., S. M. Denning, K. H. Singer, and J. Kurtzberg. “Ontogeny of T-cell precursors: a model for the initial stages of human T-cell development.” Immunol Today 10, no. 3 (March 1989): 87–91. https://doi.org/10.1016/0167-5699(89)90232-6.Full Text Link to Item
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Kurtzberg, J., T. A. Waldmann, M. P. Davey, S. H. Bigner, J. O. Moore, M. S. Hershfield, and B. F. Haynes. “CD7+, CD4-, CD8- acute leukemia: a syndrome of malignant pluripotent lymphohematopoietic cells.” Blood 73, no. 2 (February 1989): 381–90.Link to Item
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Palker, T. J., M. E. Tanner, R. M. Scearce, R. D. Streilein, M. E. Clark, and B. F. Haynes. “Mapping of immunogenic regions of human T cell leukemia virus type I (HTLV-I) gp46 and gp21 envelope glycoproteins with env-encoded synthetic peptides and a monoclonal antibody to gp46.” J Immunol 142, no. 3 (February 1, 1989): 971–78.Link to Item
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Singer, K. H., R. M. Scearce, D. T. Tuck, L. P. Whichard, S. M. Denning, and B. F. Haynes. “Removal of fibroblasts from human epithelial cell cultures with use of a complement fixing monoclonal antibody reactive with human fibroblasts and monocytes/macrophages.” J Invest Dermatol 92, no. 2 (February 1989): 166–70. https://doi.org/10.1111/1523-1747.ep12276685.Full Text Link to Item
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Denning, S. M., J. Kurtzberg, D. S. Leslie, and B. F. Haynes. “Human postnatal CD4- CD8- CD3- thymic T cell precursors differentiate in vitro into T cell receptor δ-bearing cells.” Journal of Immunology 142, no. 9 (1989): 2988–97.
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Hale, L. P., M. E. Martin, D. E. McCollum, J. A. Nunley, T. A. Springer, K. H. Singer, and B. F. Haynes. “Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment.” Arthritis Rheum 32, no. 1 (January 1989): 22–30. https://doi.org/10.1002/anr.1780320105.Full Text Link to Item
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Haynes, B. F., L. P. Hale, S. M. Denning, P. T. Le, and K. H. Singer. “The role of leukocyte adhesion molecules in cellular interactions: implications for the pathogenesis of inflammatory synovitis.” Springer Semin Immunopathol 11, no. 2 (1989): 163–85. https://doi.org/10.1007/BF00197187.Full Text Link to Item
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Haynes, B. F., K. H. Singer, S. M. Denning, and M. E. Martin. “Analysis of expression of CD2, CD3, and T cell antigen receptor molecules during early human fetal thymic development.” J Immunol 141, no. 11 (December 1, 1988): 3776–84.Link to Item
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Denning, S. M., M. L. Dustin, T. A. Springer, K. H. Singer, and B. F. Haynes. “Purified lymphocyte function-associated antigen-3 (LFA-3) activates human thymocytes via the CD2 pathway.” J Immunol 141, no. 9 (November 1, 1988): 2980–85.Link to Item
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Yang, S. Y., S. M. Denning, S. Mizuno, B. Dupont, and B. F. Haynes. “A novel activation pathway for mature thymocytes. Costimulation of CD2 (T,p50) and CD28 (T,p44) induces autocrine interleukin 2/interleukin 2 receptor-mediated cell proliferation.” J Exp Med 168, no. 4 (October 1, 1988): 1457–68. https://doi.org/10.1084/jem.168.4.1457.Full Text Link to Item
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Kraus, V. B., E. A. Harden, B. Wittels, J. O. Moore, and B. F. Haynes. “Demonstration of phenotypic abnormalities of thymic epithelium in thymoma including two cases with abundant Langerhans cells.” Am J Pathol 132, no. 3 (September 1988): 552–62.Link to Item
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Haynes, B. F., M. E. Martin, H. H. Kay, and J. Kurtzberg. “Early events in human T cell ontogeny. Phenotypic characterization and immunohistologic localization of T cell precursors in early human fetal tissues.” J Exp Med 168, no. 3 (September 1, 1988): 1061–80. https://doi.org/10.1084/jem.168.3.1061.Full Text Link to Item
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Le, P. T., J. Kurtzberg, S. J. Brandt, J. E. Niedel, B. F. Haynes, and K. H. Singer. “Human thymic epithelial cells produce granulocyte and macrophage colony-stimulating factors.” J Immunol 141, no. 4 (August 15, 1988): 1211–17.Link to Item
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Haynes, B. F., B. J. Grover, L. P. Whichard, L. P. Hale, J. A. Nunley, D. E. McCollum, and K. H. Singer. “Synovial microenvironment-T cell interactions. Human T cells bind to fibroblast-like synovial cells in vitro.” Arthritis Rheum 31, no. 8 (August 1988): 947–55. https://doi.org/10.1002/art.1780310802.Full Text Link to Item
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Weinberg, J. B., R. A. Spiegel, D. L. Blazey, R. S. Janssen, J. E. Kaplan, M. Robert-Guroff, M. Popovic, T. J. Matthews, B. F. Haynes, and T. J. Palker. “Human T-cell lymphotropic virus I and adult T-cell leukemia: report of a cluster in North Carolina.” Am J Med 85, no. 1 (July 1988): 51–58. https://doi.org/10.1016/0002-9343(88)90502-5.Full Text Link to Item
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Denning, S. M., J. Kurtzberg, P. T. Le, D. T. Tuck, K. H. Singer, and B. F. Haynes. “Human thymic epithelial cells directly induce activation of autologous immature thymocytes.” Proc Natl Acad Sci U S A 85, no. 9 (May 1988): 3125–29. https://doi.org/10.1073/pnas.85.9.3125.Full Text Link to Item
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DENNING, S. M., K. H. SINGER, P. T. LE, and B. F. HAYNES. “CD2 PATHWAY ACTIVATION OF HUMAN CD4-THYMOCYTES, CD8-THYMOCYTES.” Clinical Research 36, no. 3 (April 1, 1988): A573–A573.Link to Item
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DENNING, S. M., M. L. DUSTIN, T. A. SPRINGER, K. H. SINGER, and B. F. HAYNES. “PURIFIED LFA-3 ANTIGEN ACTIVATES HUMAN THYMOCYTES VIA THE CD2 PATHWAY.” Clinical Research 36, no. 3 (April 1, 1988): A573–A573.Link to Item
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HALE, L. P., B. J. GROVER, M. E. MARTIN, L. P. WHICHARD, K. H. SINGER, and B. F. HAYNES. “SYNOVIAL CELL-T CELL-INTERACTIONS IN INFLAMMATORY SYNOVITIS - STUDY OF THE ROLE OF THE CD2-LFA-3 ADHESION PATHWAY.” Clinical Research 36, no. 3 (April 1, 1988): A532–A532.Link to Item
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LE, P. T., J. KURTZBERG, S. J. BRANDT, J. E. NIEDEL, B. F. HAYNES, and K. H. SINGER. “HUMAN THYMIC EPITHELIAL-CELLS PRODUCE GRANULOCYTE AND MACROPHAGE COLONY-STIMULATING FACTORS.” Clinical Research 36, no. 3 (April 1, 1988): A666–A666.Link to Item
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LE, P. T., J. KURTZBERG, S. J. BRANDT, J. E. NIEDEL, B. F. HAYNES, and K. H. SINGER. “HUMAN THYMIC EPITHELIAL-CELLS PRODUCE GRANULOCYTE AND MACROPHAGE COLONY-STIMULATING FACTORS.” Journal of Investigative Dermatology 90, no. 4 (April 1, 1988): 580–580.Link to Item
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PALKER, T. J., M. E. TANNER, R. M. SCEARCE, A. LANGLOIS, T. J. MATTHEWS, D. P. BOLOGNESI, and B. F. HAYNES. “NEUTRALIZATION OF 2 HUMAN IMMUNODEFICIENCY VIRUS (HIV) ISOLATES WITH A BIVALENT ANTI-SYNTHETIC PEPTIDE ANTISERUM TO NEUTRALIZING DETERMINANTS OF GP120.” Clinical Research 36, no. 3 (April 1, 1988): A465–A465.Link to Item
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PALKER, T. J., M. E. TANNER, R. M. SCEARCE, M. E. CLARK, and B. F. HAYNES. “MAPPING OF IMMUNOGENIC REGIONS OF HUMAN T-CELL LYMPHOTROPIC VIRUS TYPE-I (HTLV-I) GP46 ENVELOPE GLYCOPROTEIN WITH A MURINE MONOCLONAL-ANTIBODY TO GP46 AND ENV-ENCODED SYNTHETIC PEPTIDES.” Clinical Research 36, no. 3 (April 1, 1988): A465–A465.Link to Item
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YANG, S. Y., S. DENNING, B. DUPONT, and B. HAYNES. “A NOVEL ACTIVATION PATHWAY FOR MATURE THYMOCYTES.” Faseb Journal 2, no. 5 (March 20, 1988): A1457–A1457.Link to Item
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Palker, T. J., M. E. Clark, A. J. Langlois, T. J. Matthews, K. J. Weinhold, R. R. Randall, D. P. Bolognesi, and B. F. Haynes. “Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides.” Proc Natl Acad Sci U S A 85, no. 6 (March 1988): 1932–36. https://doi.org/10.1073/pnas.85.6.1932.Full Text Link to Item
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Denning, S. M., and B. F. Haynes. “Differentiation of human T cells.” Clin Lab Med 8, no. 1 (March 1988): 1–14.Link to Item
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Denning, S. M., D. T. Tuck, L. W. Vollger, T. A. Springer, K. H. Singer, and B. F. Haynes. “Monoclonal antibodies to CD2 and lymphocyte function-associated antigen 3 inhibit human thymic epithelial cell-dependent mature thymocyte activation.” J Immunol 139, no. 8 (October 15, 1987): 2573–78.Link to Item
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Singer, K. H., and B. F. Haynes. “Epithelial-thymocyte interactions in human thymus.” Hum Immunol 20, no. 2 (October 1987): 127–44. https://doi.org/10.1016/0198-8859(87)90027-9.Full Text Link to Item
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Haleem, A., J. Kurtzberg, G. A. Olsen, A. Rhinehardt-Clark, D. S. Leslie, L. Ray, C. A. Smith, W. P. Peters, B. F. Haynes, and R. C. Bast. “Combined chemoseparation and immunoseparation of clonogenic T lymphoma cells from human bone marrow using 2'-deoxycoformycin, deoxyadenosine, 3A1 monoclonal antibody, and complement.” Cancer Res 47, no. 17 (September 1, 1987): 4608–12.Link to Item
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Laster, A. J., D. S. Pisetsky, and B. F. Haynes. “Polyspecific reactivity of a murine monoclonal antibody that binds to nuclear matrix-associated, chromatin-bound autoantigens.” Clin Immunol Immunopathol 44, no. 2 (August 1987): 187–205. https://doi.org/10.1016/0090-1229(87)90065-1.Full Text Link to Item
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Srikanta, S., M. Telen, J. T. Posillico, R. Dolinar, K. Krisch, B. F. Haynes, and G. S. Eisenbarth. “Monoclonal antibodies to a human islet cell surface glycoprotein: 4F2 and LC7-2.” Endocrinology 120, no. 6 (June 1987): 2240–44. https://doi.org/10.1210/endo-120-6-2240.Full Text Link to Item
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Le, P. T., D. T. Tuck, C. A. Dinarello, B. F. Haynes, and K. H. Singer. “Human thymic epithelial cells produce interleukin 1.” J Immunol 138, no. 8 (April 15, 1987): 2520–26.Link to Item
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Palker, T. J., T. J. Matthews, M. E. Clark, G. J. Cianciolo, R. R. Randall, A. J. Langlois, G. C. White, B. Safai, R. Snyderman, and D. P. Bolognesi. “A conserved region at the COOH terminus of human immunodeficiency virus gp120 envelope protein contains an immunodominant epitope.” Proc Natl Acad Sci U S A 84, no. 8 (April 1987): 2479–83. https://doi.org/10.1073/pnas.84.8.2479.Full Text Link to Item
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DENNING, S., P. LE, T. SPRINGER, K. SINGER, and B. HAYNES. “HUMAN THYMIC EPITHELIAL-CELLS DIRECTLY ACTIVATE AUTOLOGOUS IMMATURE THYMOCYTES.” Federation Proceedings 46, no. 3 (March 1, 1987): 918–918.Link to Item
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HAYNES, B., J. KURTZBERG, D. LOBACH, S. DENNING, and K. SINGER. “PHENOTYPIC CHARACTERIZATION OF T-CELL PRECURSORS DURING HUMAN-DEVELOPMENT.” Federation Proceedings 46, no. 3 (March 1, 1987): 449–449.Link to Item
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LE, P., S. DENNING, T. SPRINGER, B. HAYNES, and K. SINGER. “ANTI-LFA-3 MONOCLONAL-ANTIBODY INDUCES INTERLEUKIN-1 (IL-1) RELEASE BY THYMIC EPITHELIAL (TE) CELLS AND MONOCYTES.” Federation Proceedings 46, no. 3 (March 1, 1987): 447–447.Link to Item
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PALKER, T., T. MATTHEWS, M. CLARK, A. LANGLOIS, G. CIANCIOLO, G. WHITE, B. SAFAI, R. SNYDERMAN, D. BOLOGNESI, and B. HAYNES. “A CONSERVED REGION AT THE C-TERMINUS OF HUMAN-IMMUNODEFICIENCY-VIRUS GP120 ENVELOPE PROTEIN CONTAINS AN IMMUNODOMINANT EPITOPE.” Federation Proceedings 46, no. 3 (March 1, 1987): 624–624.Link to Item
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VOLLGER, L., S. DENNING, D. TUCK, T. SPRINGER, B. HAYNES, and K. SINGER. “CD-2 (T11) AND LFA-3 MOLECULES MEDIATE THYMOCYTE INTERACTIONS WITH THYMIC EPITHELIUM.” Federation Proceedings 46, no. 3 (March 1, 1987): 763–763.Link to Item
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Lobach, D. F., and B. F. Haynes. “Ontogeny of the human thymus during fetal development.” J Clin Immunol 7, no. 2 (March 1987): 81–97. https://doi.org/10.1007/BF00916002.Full Text Link to Item
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Denning, S. M., D. T. Tuck, K. H. Singer, and B. F. Haynes. “Human thymic epithelial cells function as accessory cells for autologous mature thymocyte activation.” J Immunol 138, no. 3 (February 1, 1987): 680–86.Link to Item
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Vollger, L. W., D. T. Tuck, T. A. Springer, B. F. Haynes, and K. H. Singer. “Thymocyte binding to human thymic epithelial cells is inhibited by monoclonal antibodies to CD-2 and LFA-3 antigens.” J Immunol 138, no. 2 (January 15, 1987): 358–63.Link to Item
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KURTZBERG, J., S. DENNING, P. LE, K. SINGER, M. HERSHFIELD, and B. HAYNES. “BIOLOGY OF THE NORMAL AND LEUKEMIC CD-7+ STEM-CELL.” Journal of Cellular Biochemistry, January 1, 1987, 235–235.Link to Item
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Lobach, D. F., T. Itoh, K. H. Singer, and B. F. Haynes. “The thymic microenvironment. Characterization of in vitro differentiation of the IT26R21 rat thymic epithelial cell line.” Differentiation 34, no. 1 (1987): 50–59. https://doi.org/10.1111/j.1432-0436.1987.tb00050.x.Full Text Link to Item
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PALKER, T. J., T. J. MATTHEWS, M. E. CLARK, A. LANGLOIS, G. J. CIANCIOLO, R. RANDALL, G. WHITE, et al. “MAPPING OF IMMUNOGENIC AND IMMUNODOMINANT EPITOPES ON HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) GP120 USING ENV-ENCODED SYNTHETIC PEPTIDES.” Journal of Cellular Biochemistry, January 1, 1987, 46–46.Link to Item
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Telen, M. J., R. M. Scearce, and B. F. Haynes. “Human erythrocyte antigens. III. Characterization of a panel of murine monoclonal antibodies that react with human erythrocyte and erythroid precursor membranes.” Vox Sang 52, no. 3 (1987): 236–43. https://doi.org/10.1111/j.1423-0410.1987.tb03035.x.Full Text Link to Item
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Davey, M. P., K. F. Bongiovanni, W. Kaulfersch, T. Quertermous, J. G. Seidman, M. S. Hershfield, J. Kurtzberg, B. F. Haynes, M. M. Davis, and T. A. Waldmann. “Immunoglobulin and T-cell receptor gene rearrangement and expression in human lymphoid leukemia cells at different stages of maturation.” Proc Natl Acad Sci U S A 83, no. 22 (November 1986): 8759–63. https://doi.org/10.1073/pnas.83.22.8759.Full Text Link to Item
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Telen, M. J., H. Shehata, and B. F. Haynes. “Human medullary thymocyte p80 antigen and In(Lu)-related p80 antigen reside on the same protein.” Hum Immunol 17, no. 3 (November 1986): 311–24. https://doi.org/10.1016/0198-8859(86)90283-1.Full Text Link to Item
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Laster, A. J., and B. F. Haynes. “Characterization of a monoclonal antibody, RTE-21, that binds to keratohyalin granule-associated proteins in epithelial cells of human skin and thymus.” Clin Immunol Immunopathol 41, no. 1 (October 1986): 130–44. https://doi.org/10.1016/0090-1229(86)90057-7.Full Text Link to Item
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Haynes, B. F. “The role of the thymic microenvironment in promotion of early stages of human T cell maturation.” Clin Res 34, no. 3 (September 1986): 422–31.Link to Item
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Singer, K. H., L. S. Wolf, D. F. Lobach, S. M. Denning, D. T. Tuck, A. L. Robertson, and B. F. Haynes. “Human thymocytes bind to autologous and allogeneic thymic epithelial cells in vitro.” Proc Natl Acad Sci U S A 83, no. 17 (September 1986): 6588–92. https://doi.org/10.1073/pnas.83.17.6588.Full Text Link to Item
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DENNING, S. M., D. T. TUCK, K. H. SINGER, and B. F. HAYNES. “HUMAN THYMIC EPITHELIAL-CELLS FUNCTION AS ACCESSORY CELLS FOR AUTOLOGOUS THYMOCYTE ACTIVATION.” Clinical Research 34, no. 2 (April 1, 1986): A669–A669.Link to Item
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LASTER, A. J., D. S. PISETSKY, and B. F. HAYNES. “PRODUCTION OF A MONOCLONAL-ANTIBODY THAT DEFINES A NUCLEAR MATRIX ASSOCIATED, CHROMATIN BOUND, AUTOANTIGEN.” Clinical Research 34, no. 2 (April 1, 1986): A704–A704.Link to Item
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LASTER, A. J., and B. F. HAYNES. “USE OF A MONOCLONAL-ANTIBODY SPECIFIC FOR KERATOHYALINE GRANULES (KHG) TO CHARACTERIZE ABNORMAL EPITHELIAL MATURATION IN SKIN AND THYMUS.” Clinical Research 34, no. 2 (April 1, 1986): A761–A761.Link to Item
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LASTER, A. J., and B. F. HAYNES. “USE OF A MONOCLONAL-ANTIBODY SPECIFIC FOR KERATOHYALINE GRANULES (KHG) TO CHARACTERIZE ABNORMAL EPITHELIAL MATURATION IN SKIN AND THYMUS.” Journal of Investigative Dermatology 86, no. 4 (April 1, 1986): 487–487.Link to Item
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LE, P. T., D. T. TUCK, C. A. DINARELLO, B. F. HAYNES, and K. H. SINGER. “INTERLEUKIN-1 (IL-1) IS PRODUCED BY HUMAN THYMIC EPITHELIAL-CELLS.” Clinical Research 34, no. 2 (April 1, 1986): A499–A499.Link to Item
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LOBACH, D. F., K. H. SINGER, and B. F. HAYNES. “DEMONSTRATION OF THYMIC EPITHELIAL-CELL DIFFERENTIATION INVITRO.” Clinical Research 34, no. 2 (April 1, 1986): A500–A500.Link to Item
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MCCALLUM, R. M., L. M. COBO, G. N. FOULKS, K. H. SINGER, and B. F. HAYNES. “IMMUNOPATHOGENESIS OF RHEUMATIC INFLAMMATORY OCULAR DISEASE - GAMMA-INTERFERON (GAMMA-IF) INDUCES MHC CLASS-II (IA) EXPRESSION BY CORNEAL EPITHELIAL-CELLS.” Clinical Research 34, no. 2 (April 1, 1986): A619–A619.Link to Item
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Palker, T. J., R. M. Scearce, T. D. Copeland, S. Oroszlan, and B. F. Haynes. “C-terminal region of human T cell lymphotropic virus type I (HTLVI) p19 core protein is immunogenic in humans and contains an HTLVI-specific epitope.” J Immunol 136, no. 7 (April 1, 1986): 2393–97.Link to Item
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WOLF, L. S., D. T. TUCK, T. A. SPRINGER, B. F. HAYNES, and K. H. SINGER. “MONOCLONAL-ANTIBODIES TO T11, LFA-2, AND LFA-3 ANTIGENS INHIBIT BINDING OF HUMAN THYMOCYTES TO AUTOLOGOUS THYMIC EPITHELIAL-CELLS.” Pediatric Research 20, no. 4 (April 1, 1986): A303–A303.Link to Item
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WOLF, L. S., D. T. TUCK, T. A. SPRINGER, B. F. HAYNES, and K. H. SINGER. “MONOCLONAL-ANTIBODIES TO T11, LFA-2, AND LFA-3 ANTIGENS INHIBIT BINDING OF HUMAN THYMOCYTES TO AUTOLOGOUS THYMIC EPITHELIAL-CELLS.” Clinical Research 34, no. 2 (April 1, 1986): A674–A674.Link to Item
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White, G. C., T. J. Matthews, K. J. Weinhold, B. F. Haynes, H. L. Cromartie, C. W. McMillan, and D. P. Bolognesi. “HTLV-III seroconversion associated with heat-treated factor VIII concentrate.” Lancet 1, no. 8481 (March 15, 1986): 611–12. https://doi.org/10.1016/s0140-6736(86)92828-x.Full Text Link to Item
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LE, P. T., D. T. TUCK, C. A. DINARELLO, B. F. HAYNES, and K. H. SINGER. “HUMAN THYMIC EPITHELIAL-CELLS PRODUCE INTERLEUKIN-1 (IL-1).” Federation Proceedings 45, no. 4 (March 5, 1986): 1112–1112.Link to Item
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Haynes, B. F., N. B. Allen, and A. S. Fauci. “Diagnostic and therapeutic approach to the patient with vasculitis.” Med Clin North Am 70, no. 2 (March 1986): 355–68. https://doi.org/10.1016/s0025-7125(16)30958-0.Full Text Link to Item
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MONTGOMERY, R. B., A. HALEEM, S. RAMAKRISHNAN, G. A. OLSEN, W. P. PETERS, C. A. SMITH, J. KURTZBERG, B. F. HAYNES, L. L. HOUSTON, and R. C. BAST. “ELIMINATION OF MALIGNANT CLONOGENIC T-CELLS FROM BONE-MARROW USING CHEMOIMMUNOSEPARATION WITH AN IMMUNOTOXIN AND 2'-DEOXYCOFORMYCIN-DEOXYADENOSINE (DCF/DADO).” Proceedings of the American Association for Cancer Research 27 (March 1, 1986): 380–380.Link to Item
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Laster, A. J., T. Itoh, T. J. Palker, and B. F. Haynes. “The human thymic microenvironment: thymic epithelium contains specific keratins associated with early and late stages of epidermal keratinocyte maturation.” Differentiation 31, no. 1 (1986): 67–77. https://doi.org/10.1111/j.1432-0436.1986.tb00385.x.Full Text Link to Item
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Laster, A. J., T. J. Palker, E. A. Harden, W. Ho, K. Naito, B. DuPont, and B. F. Haynes. “Antibody against T lymphoblastic leukemia-associated antigen (3-40) identifies vimentin and keratin intermediate filaments in normal cells.” Blood 66, no. 3 (September 1985): 642–48.Link to Item
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Lobach, D. F., L. L. Hensley, W. Ho, and B. F. Haynes. “Human T cell antigen expression during the early stages of fetal thymic maturation.” J Immunol 135, no. 3 (September 1985): 1752–59.Link to Item
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Palker, T. J., R. M. Scearce, W. Ho, T. D. Copeland, S. Oroszlan, M. Popovic, and B. F. Haynes. “Monoclonal antibodies reactive with human T cell lymphotropic virusI (HTLVI) p19 internal core protein: cross-reactivity with normal tissues and differential reactivity with HTLV types I and II.” J Immunol 135, no. 1 (July 1985): 247–54.Link to Item
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Singer, K. H., E. A. Harden, A. L. Robertson, D. F. Lobach, and B. F. Haynes. “In vitro growth and phenotypic characterization of mesodermal-derived and epithelial components of normal and abnormal human thymus.” Hum Immunol 13, no. 3 (July 1985): 161–76. https://doi.org/10.1016/0198-8859(85)90009-6.Full Text Link to Item
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Singer, K. H., E. A. Harden, A. L. Robertson, D. F. Lobach, and B. F. Haynes. “Expression of antigens by cultured epithelial cells: comparison of epidermis and thymic epithelium.” J Invest Dermatol 85, no. 1 Suppl (July 1985): 67s-71s. https://doi.org/10.1111/1523-1747.ep12275490.Full Text Link to Item
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BAST, R. C., L. RAY, A. HALEEM, T. LEBIEN, L. NADLER, J. RITZ, G. OLSEN, W. PETERS, J. KURTZBERG, and B. HAYNES. “SELECTIVE REMOVAL OF MALIGNANT B-CELL AND T-CELL NEOPLASMS FROM HUMAN-BONE MARROW.” International Journal of Cell Cloning 3, no. 4 (January 1, 1985): 227–227.Link to Item
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HAYNES, B., G. WHITE, T. PALKER, R. SCEARCE, W. HO, J. HAMILTON, P. FOSTER, et al. “CLINICAL AND VIROLOGIC CORRELATES OF SERUM ANTIBODIES TO HUMAN T-CELL LYMPHOTROPIC VIRUS (HTLV) TYPE-I, TYPE-II, AND TYPE-III IN HEMOPHILIA.” Clinical Research 33, no. 2 (January 1, 1985): A342–A342.Link to Item
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Harden, E. A., and B. F. Haynes. “Phenotypic and functional characterization of human malignant T cells.” Semin Hematol 22, no. 1 (January 1985): 13–26.Link to Item
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LASTER, A. J., B. DUPONT, K. NAITO, W. HO, and B. F. HAYNES. “ANTIBODY AGAINST T-LYMPHOBLASTIC LEUKEMIA ASSOCIATED ANTIGEN (3-40) IDENTIFIES VIMENTIN AND KERATIN INTERMEDIATE FILAMENTS IN NORMAL-CELLS.” Clinical Research 33, no. 2 (January 1, 1985): A346–A346.Link to Item
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LASTER, A. J., and B. F. HAYNES. “HUMAN THYMIC EPITHELIAL-CELLS CONTAIN KERATINS OF DIFFERENTIATED CORNIFIED EPITHELIUM.” Clinical Research 33, no. 2 (January 1, 1985): A381–A381.Link to Item
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LOBACH, D. F., L. L. HENSLEY, W. HO, and B. F. HAYNES. “ONTOGENY OF HUMAN T-CELL ANTIGENS.” Clinical Research 33, no. 2 (January 1, 1985): A559–A559.Link to Item
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Lobach, D. F., R. M. Scearce, and B. F. Haynes. “The human thymic microenvironment. Phenotypic characterization of Hassall's bodies with the use of monoclonal antibodies.” J Immunol 134, no. 1 (January 1985): 250–57.Link to Item
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MCCALLUM, R. M., T. J. PALKER, L. M. COBO, and B. F. HAYNES. “PHENOTYPIC DIFFERENCES BETWEEN EPITHELIAL KERATINOCYTES OF HUMAN CONJUNCTIVA AND CORNEA.” Clinical Research 33, no. 2 (January 1, 1985): A301–A301.Link to Item
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PALKER, T. J., L. L. HENSLEY, S. OROSZLAN, and B. F. HAYNES. “MONOCLONAL-ANTIBODY TO HTLV P19 CORE PROTEIN REACTS WITH A SUBSET OF KERATIN INTERMEDIATE FILAMENTS IN HUMAN THYMIC EPITHELIUM.” Clinical Research 33, no. 2 (January 1, 1985): A560–A560.Link to Item
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PALKER, T. J., R. M. SCEARCE, T. D. COPELAND, S. OROSZLAN, and B. F. HAYNES. “IDENTIFICATION OF AN IMMUNOGENIC EPITOPE SPECIFIC FOR HTLV-I AT THE C-TERMINUS OF HTLV-I P19 CORE PROTEIN.” Clinical Research 33, no. 2 (January 1, 1985): A549–A549.Link to Item
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Palker, T. J., D. P. Bolognesi, and B. F. Haynes. “Human T-cell leukemia/lymphoma virus: studies of host-virus interaction.” Curr Top Microbiol Immunol 115 (1985): 247–66. https://doi.org/10.1007/978-3-642-70113-9_16.Full Text Link to Item
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SINGER, K., A. ROBERTSON, R. SCEARCE, L. HENSLEY, and B. HAYNES. “MONOCLONAL AUTOANTIBODIES TO KERATINS DISTINGUISH SUBSETS OF HUMAN-SKIN AND THYMIC EPITHELIUM.” Clinical Research 33, no. 2 (January 1, 1985): A682–A682.Link to Item
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SINGER, K., A. ROBERTSON, R. SCEARCE, L. HENSLEY, and B. HAYNES. “MONOCLONAL AUTOANTIBODIES TO KERATINS DISTINGUISH SUBSETS OF HUMAN-SKIN AND THYMIC EPITHELIUM.” Journal of Investigative Dermatology 84, no. 4 (January 1, 1985): 325–26.Link to Item
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Haynes, B. F. “Phenotypic characterization and ontogeny of components of the human thymic microenvironment.” Clin Res 32, no. 5 (December 1984): 500–507.Link to Item
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Harden, E. A., J. O. Moore, and B. F. Haynes. “Leukemia-associated arthritis: identification of leukemic cells in synovial fluid using monoclonal and polyclonal antibodies.” Arthritis Rheum 27, no. 11 (November 1984): 1306–8. https://doi.org/10.1002/art.1780271114.Full Text Link to Item
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Golightly, M. G., H. S. Koren, W. W. Travis, C. P. Brandt, B. F. Haynes, D. Kraft, and H. Rumpold. “Selective inhibition of natural killer activity by the monoclonal antibodies OKT10 and VEP10 at the single cell level.” Cell Immunol 88, no. 2 (October 15, 1984): 382–92. https://doi.org/10.1016/0008-8749(84)90171-0.Full Text Link to Item
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McFarland, E. J., R. M. Scearce, and B. F. Haynes. “The human thymic microenvironment: cortical thymic epithelium is an antigenically distinct region of the thymic microenvironment.” J Immunol 133, no. 3 (September 1984): 1241–49.Link to Item
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Patterson, J. A., M. Eisinger, B. F. Haynes, C. L. Berger, and R. L. Edelson. “Monoclonal antibody 4F2 reactive with basal layer keratinocytes: studies in the normal and a hyperproliferative state.” J Invest Dermatol 83, no. 3 (September 1984): 210–13. https://doi.org/10.1111/1523-1747.ep12263581.Full Text Link to Item
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Telen, M. J., T. J. Palker, and B. F. Haynes. “Human erythrocyte antigens: II. The In(Lu) gene regulates expression of an antigen on an 80-kilodalton protein of human erythrocytes.” Blood 64, no. 3 (September 1984): 599–606.Link to Item
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Cobo, L. M., and B. F. Haynes. “Early corneal findings in Cogan's syndrome.” Ophthalmology 91, no. 8 (August 1984): 903–7. https://doi.org/10.1016/s0161-6420(84)34215-4.Full Text Link to Item
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Jackson, R. A., B. F. Haynes, W. M. Burch, K. Shimizu, M. A. Bowring, and G. S. Eisenbarth. “Ia+ T cells in new onset Graves' disease.” J Clin Endocrinol Metab 59, no. 2 (August 1984): 187–90. https://doi.org/10.1210/jcem-59-2-187.Full Text Link to Item
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GRUFFERMAN, S. E. Y. M. O. U. R., SUE Y. S. KIMM, and MARLA C. MAILE. “TEACHING EPIDEMIOLOGY IN MEDICAL SCHOOLS: A WORKABLE MODEL.” American Journal of Epidemiology 120, no. 2 (August 1984): 203–9. https://doi.org/10.1093/oxfordjournals.aje.a113882.Full Text
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Michels, M. L., L. M. Cobo, D. S. Caldwell, J. R. Rice, and B. F. Haynes. “Rheumatoid arthritis and sterile corneal ulceration. Analysis of tissue immune effector cells and ocular epithelial antigens using monoclonal antibodies.” Arthritis Rheum 27, no. 6 (June 1984): 606–14. https://doi.org/10.1002/art.1780270602.Full Text Link to Item
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Gallo, R. C., S. Z. Salahuddin, M. Popovic, G. M. Shearer, M. Kaplan, B. F. Haynes, T. J. Palker, R. Redfield, J. Oleske, and B. Safai. “Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS.” Science 224, no. 4648 (May 4, 1984): 500–503. https://doi.org/10.1126/science.6200936.Full Text Link to Item
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Haynes, B. F., M. J. Telen, M. J. PalkerTJ, E. Harden, and R. M. Scearce. “Monoclonal antibody defines human cell surface protein p80 on intrathymic T cells.” J Immunol 132, no. 5 (May 1984): 2678.Link to Item
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Haynes, B. F., R. M. Scearce, D. F. Lobach, and L. L. Hensley. “Phenotypic characterization and ontogeny of mesodermal-derived and endocrine epithelial components of the human thymic microenvironment.” J Exp Med 159, no. 4 (April 1, 1984): 1149–68. https://doi.org/10.1084/jem.159.4.1149.Full Text Link to Item
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Mokhtar, N., S. M. Hsu, R. P. Lad, B. F. Haynes, and E. S. Jaffe. “Thymoma: lymphoid and epithelial components mirror the phenotype of normal thymus.” Hum Pathol 15, no. 4 (April 1984): 378–84. https://doi.org/10.1016/s0046-8177(84)80037-4.Full Text Link to Item
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Palker, T. J., R. M. Scearce, S. E. Miller, M. Popovic, D. P. Bolognesi, R. C. Gallo, and B. F. Haynes. “Monoclonal antibodies against human T cell leukemia-lymphoma virus (HTLV) p24 internal core protein. Use as diagnostic probes and cellular localization of HTLV.” J Exp Med 159, no. 4 (April 1, 1984): 1117–31. https://doi.org/10.1084/jem.159.4.1117.Full Text Link to Item
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CIANCIOLO, G., T. PALKER, R. KIPNIS, B. HAYNES, and R. SNYDERMAN. “ANTIGENIC AND AMINO-ACID-SEQUENCE HOMOLOGY BETWEEN HTLV AND THE RETROVIRUS ENVELOPE PROTEIN-P15E.” Journal of Leukocyte Biology 36, no. 2 (January 1, 1984): 213–14.Link to Item
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HAYNES, B. F., D. F. LOBACH, E. A. HARDEN, K. H. SINGER, L. L. HENSLEY, and R. M. SCEARCE. “ONTOGENY OF THE HUMAN THYMIC MICROENVIRONMENT - DEMONSTRATION OF ARREST OF THYMIC EPITHELIAL MATURATION IN CONGENITAL THYMIC DYSPLASIA AND THYMOMA.” Clinical Research 32, no. 2 (January 1, 1984): A504–A504.Link to Item
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Hershfield, M. S., J. Kurtzberg, E. Harden, J. O. Moore, J. Whang-Peng, and B. F. Haynes. “Conversion of a stem cell leukemia from a T-lymphoid to a myeloid phenotype induced by the adenosine deaminase inhibitor 2'-deoxycoformycin.” Proc Natl Acad Sci U S A 81, no. 1 (January 1984): 253–57. https://doi.org/10.1073/pnas.81.1.253.Full Text Link to Item
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Jackson, R. A., B. F. Haynes, W. M. Burch, K. Shimizu, M. A. Bowring, and G. S. Eisenbarth. “Ia+ T cells in new onset Graves' disease.” Journal of Clinical Endocrinology and Metabolism 59, no. 2 (1984): 187–90.
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MCFARLAND, E. J., R. M. SCEARCE, and B. F. HAYNES. “HUMAN CORTICAL THYMIC EPITHELIUM IS AN ANTIGENICALLY DISTINCT REGION OF THE THYMIC MICROENVIRONMENT.” Clinical Research 32, no. 2 (January 1, 1984): A353–A353.Link to Item
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PALKER, T. J., R. M. SCEARCE, M. POPOVIC, R. C. GALLO, D. P. BOLOGNESI, and B. F. HAYNES. “MONOCLONAL-ANTIBODIES AGAINST HUMAN T-CELL LEUKEMIA-LYMPHOMA VIRUS (HTLV) P24 INTERNAL CORE PROTEIN - RECOGNITION OF HTLVI AND HTLVII INFECTED T-CELLS AND CELLULAR-LOCALIZATION OF HTLV.” Clinical Research 32, no. 2 (January 1, 1984): A421–A421.Link to Item
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PALKER, T. J., R. M. SCEARCE, W. HO, D. P. BOLOGNESI, and B. F. HAYNES. “CROSS-REACTIVITY OF HUMAN T-CELL LEUKEMIA-VIRUS (HTLV) STRUCTURAL PROTEINS AND HOST TISSUE - DEMONSTRATION OF 4 DISTINCT ANTIGENIC SITES ON HTLV P19 INTERNAL CORE PROTEIN.” Clinical Research 32, no. 2 (January 1, 1984): A318–A318.Link to Item
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PERRY, M. D., M. J. BOROWITZ, H. KOREN, and B. HAYNES. “NK CELL LEUKEMIA - A HISTOLOGIC MIMIC OF MALIGNANT HISTIOCYTOSIS.” Laboratory Investigation 50, no. 1 (January 1, 1984): A45–A45.Link to Item
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SINGER, K. H., E. A. HARDEN, A. L. ROBERTSON, D. F. LOBACH, and B. F. HAYNES. “INVITRO CULTURE AND PHENOTYPIC CHARACTERIZATION OF HUMAN KERATINIZING EPITHELIUM - COMPARISON OF SKIN AND THYMUS.” Journal of Investigative Dermatology 82, no. 4 (January 1, 1984): 438–39.Link to Item
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SINGER, K. H., E. A. HARDEN, A. L. ROBERTSON, D. F. LOBACH, and B. F. HAYNES. “INVITRO CULTURE AND PHENOTYPIC CHARACTERIZATION OF HUMAN KERATINIZING EPITHELIUM - COMPARISON OF SKIN AND THYMUS.” Clinical Research 32, no. 2 (January 1, 1984): A615–A615.Link to Item
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Tuttle, J., B. Haynes, and D. W. Scott. “Selection of anti-μ-resistant variants of WEHI-231, a B lymphoma model of an immature B cell.” Federation Proceedings 43, no. 6 (January 1, 1984).
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Haynes, B. F. “The human thymic microenvironment.” Adv Immunol 36 (1984): 87–142. https://doi.org/10.1016/s0065-2776(08)60900-1.Full Text Link to Item
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Mann, D. L., M. Popovic, P. Sarin, C. Murray, M. S. Reitz, D. M. Strong, B. F. Haynes, R. C. Gallo, and W. A. Blattner. “Cell lines producing human T-cell lymphoma virus show altered HLA expression.” Nature 305, no. 5929 (September 1, 1983): 58–60. https://doi.org/10.1038/305058a0.Full Text Link to Item
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Haynes, B. F., E. A. Harden, M. J. Telen, M. E. Hemler, J. L. Strominger, T. J. Palker, R. M. Scearce, and G. S. Eisenbarth. “Differentiation of human T lymphocytes. I. Acquisition of a novel human cell surface protein (p80) during normal intrathymic T cell maturation.” J Immunol 131, no. 3 (September 1983): 1195–1200.Link to Item
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Haynes, B. F., E. A. Harden, C. W. Olanow, G. S. Eisenbarth, A. S. Wechsler, L. L. Hensley, and A. D. Roses. “Effect of thymectomy on peripheral lymphocyte subsets in myasthenia gravis: selective effect on T-cells in patients with thymic atrophy.” J Immunol 131, no. 2 (August 1983): 773–77.Link to Item
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Gallo, R. C., V. S. Kalyanaraman, M. G. Sarngadharan, A. Sliski, E. C. Vonderheid, M. Maeda, Y. Nakao, et al. “Association of the human type C retrovirus with a subset of adult T-cell cancers.” Cancer Res 43, no. 8 (August 1983): 3892–99.Link to Item
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Stevenson, H. C., P. J. Miller, M. J. Waxdal, B. F. Haynes, C. A. Thomas, and A. S. Fauci. “Interaction of pokeweed mitogen with monocytes in the activation of human lymphocytes.” Immunology 49, no. 4 (August 1983): 633–40.Link to Item
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Mann, D. L., B. F. Haynes, C. Thomas, D. Cole, A. S. Fauci, and D. G. Poplack. “Heterogeneity of acute lymphocytic leukemia cell surface markers as detected by monoclonal antibodies.” J Natl Cancer Inst 71, no. 1 (July 1983): 11–17.Link to Item
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Dowell, B. L., I. Gore, G. M. McCormick, B. F. Haynes, and R. S. Metzgar. “A monoclonal antibody reactive with a second epitope of the 67,000-dalton human T cell antigen.” Hum Immunol 7, no. 2 (June 1983): 95–104. https://doi.org/10.1016/s0198-8859(83)80010-x.Full Text Link to Item
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Telen, M. J., G. S. Eisenbarth, and B. F. Haynes. “Human erythrocyte antigens. Regulation of expression of a novel erythrocyte surface antigen by the inhibitor Lutheran In(Lu) gene.” J Clin Invest 71, no. 6 (June 1983): 1878–86. https://doi.org/10.1172/jci110943.Full Text Link to Item
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Francke, U., B. E. Foellmer, and B. F. Haynes. “Chromosome mapping of human cell surface molecules: monoclonal anti-human lymphocyte antibodies 4F2, A3D8, and A1G3 define antigens controlled by different regions of chromosome 11.” Somatic Cell Genet 9, no. 3 (May 1983): 333–44. https://doi.org/10.1007/BF01539142.Full Text Link to Item
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Reitz, M. S., M. Popovic, B. F. Haynes, S. C. Clark, and R. C. Gallo. “Relatedness by nucleic acid hybridization of new isolates of human T-cell leukemia-lymphoma virus (HTLV) and demonstration of provirus in uncultured leukemic blood cells.” Virology 126, no. 2 (April 30, 1983): 688–672. https://doi.org/10.1016/s0042-6822(83)80024-5.Full Text Link to Item
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Haynes, B. F., S. E. Miller, T. J. Palker, J. O. Moore, P. H. Dunn, D. P. Bolognesi, and R. S. Metzgar. “Identification of human T cell leukemia virus in a Japanese patient with adult T cell leukemia and cutaneous lymphomatous vasculitis.” Proc Natl Acad Sci U S A 80, no. 7 (April 1983): 2054–58. https://doi.org/10.1073/pnas.80.7.2054.Full Text Link to Item
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Haynes, B. F., M. Robert-Guroff, R. S. Metzgar, G. Franchini, V. S. Kalyanaraman, T. J. Palker, and R. C. Gallo. “Monoclonal antibody against human T cell leukemia virus p19 defines a human thymic epithelial antigen acquired during ontogeny.” J Exp Med 157, no. 3 (March 1, 1983): 907–20. https://doi.org/10.1084/jem.157.3.907.Full Text Link to Item
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Haynes, B. F., R. W. Warren, R. H. Buckley, J. E. McClure, A. L. Goldstein, F. W. Henderson, L. L. Hensley, and G. S. Eisenbarth. “Demonstration of abnormalities in expression of thymic epithelial surface antigens in severe cellular immunodeficiency diseases.” J Immunol 130, no. 3 (March 1983): 1182–88.Link to Item
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BUSE, J. B., S. SRIKANTA, B. HAYNES, and G. S. EISENBARTH. “TYPE-I DIABETES-MELLITUS - MONOCLONAL HUMAN AND RAT AUTOANTIBODIES REACTING WITH SUBSETS OF THYMIC ENDOCRINE EPITHELIUM.” Clinical Research 31, no. 2 (January 1, 1983): A339–A339.Link to Item
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Buckley, R. H., S. Gard, B. F. Haynes, L. J. Sindel, K. Davis, H. A. Sampson, M. E. Ruff, and H. S. Koren. “Severe combined immunodeficiency (SCID) with natural killer (NK) cell predominance.” Birth Defects Orig Artic Ser 19, no. 3 (1983): 101–4.Link to Item
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FAUCI, A. S., B. F. HAYNES, P. KATZ, and S. M. WOLFF. “ASSESSING TREATMENTS WITH CYCLOPHOSPHAMIDE - COMMENT.” Annals of Internal Medicine 98, no. 6 (January 1, 1983): 1027–1027.Link to Item
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Fauci, A. S., B. F. Haynes, P. Katz, and S. M. Wolff. “Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.” Ann Intern Med 98, no. 1 (January 1983): 76–85. https://doi.org/10.7326/0003-4819-98-1-76.Full Text Link to Item
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HARDEN, E. A., A. D. ROSES, C. W. OLANOW, and B. F. HAYNES. “DEMONSTRATION OF ABERRANT INTRATHYMIC T-CELL MATURATION IN MYASTHENIA-GRAVIS.” Clinical Research 31, no. 2 (January 1, 1983): A344–A344.Link to Item
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HAYNES, B. F., R. M. SCEARCE, and L. L. HENSLEY. “PRODUCTION OF MONOCLONAL-ANTIBODIES THAT SELECTIVELY DEFINE NEUROENDOCRINE, NON-NEUROENDOCRINE, AND HASSALL BODY COMPONENTS OF HUMAN THYMIC EPITHELIUM.” Clinical Research 31, no. 2 (January 1, 1983): A345–A345.Link to Item
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HERSHFIELD, M., J. MOORE, J. KURTZBERG, E. HARDEN, and B. HAYNES. “CONVERSION OF T-CELL TO MYELOID-LEUKEMIA BY DEOXYCOFORMYCIN (DCF), A POTENT ADENOSINE-DEAMINASE (ADA) INHIBITOR.” Proceedings of the American Association for Cancer Research 24, no. MAR (January 1, 1983): 19–19.Link to Item
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HERSHFIELD, M., J. MOORE, J. KURTZBERG, E. HARDEN, and B. HAYNES. “CONVERSION OF T-CELL TO MYELOID-LEUKEMIA BY DEOXYCOFORMYCIN (DCF), A POTENT ADENOSINE-DEAMINASE (ADA) INHIBITOR.” Clinical Research 31, no. 2 (January 1, 1983): A508–A508.Link to Item
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Haynes, B. F., K. Shimizu, and G. S. Eisenbarth. “Identification of human and rodent thymic epithelium using tetanus toxin and monoclonal antibody A2B5.” J Clin Invest 71, no. 1 (January 1983): 9–14. https://doi.org/10.1172/jci110755.Full Text Link to Item
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Haynes, B. F., R. W. Warren, R. H. Buckley, J. E. McClure, A. L. Goldstein, F. W. Henderson, L. L. Hensley, and G. S. Eisenbarth. “Demonstration of abnormalities in expression of thymic epithelial surface antigens in severe cellular immunodeficiency diseases.” Birth Defects Orig Artic Ser 19, no. 3 (1983): 255–58.Link to Item
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MATUTES, E., D. ROBINSON, M. OBRIEN, B. F. HAYNES, and D. CATOVSKY. “CANDIDATES FOR NORMAL COUNTERPARTS OF SEZARY CELLS AND ATLL CELLS IN THE PERIPHERAL-BLOOD.” British Journal of Haematology 55, no. 1 (January 1, 1983): 191–92.Link to Item
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Matutes, E., D. Robinson, M. O’Brien, B. F. Haynes, H. Zola, and D. Catovsky. “Candidate counterparts of Sézary cells and adult T-cell lymphoma-leukaemia cells in normal peripheral blood: an ultrastructural study with the immunogold method and monoclonal antibodies.” Leuk Res 7, no. 6 (1983): 787–801. https://doi.org/10.1016/0145-2126(83)90073-5.Full Text Link to Item
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Steinberg, A. D., A. Fauci, and B. F. Haynes. “Assessing treatments with cyclophosphamide.” Annals of Internal Medicine 98, no. 6 (1983): 1026–27.
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Goodwin, J. S. “Increased Ia-antigen-bearing T cells in type I diabetes mellitus.” N Engl J Med 307, no. 9 (August 26, 1982): 557. https://doi.org/10.1056/nejm198208263070914.Full Text Link to Item
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Haynes, B. F., L. L. Hensley, and B. V. Jegasothy. “Phenotypic characterization of skin-infiltrating T cells in cutaneous T-cell lymphoma: comparison with benign cutaneous T-cell infiltrates.” Blood 60, no. 2 (August 1982): 463–73.Link to Item
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Haynes, B. F., E. G. Reisner, M. E. Hemler, J. L. Strominger, and G. S. Eisenbarth. “Description of monoclonal antibody defining an HLA allotypic determinant that includes specificities within the B5 cross-reacting group.” Hum Immunol 4, no. 4 (July 1982): 273–85. https://doi.org/10.1016/0198-8859(82)90001-5.Full Text Link to Item
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Titus, J. A., B. F. Haynes, C. A. Thomas, A. S. Fauci, and D. M. Segal. “Analysis of Fc gamma receptors on human peripheral blood leukocytes by flow microfluorometry. I. Receptor distributions on monocytes, T gamma cells and cells labeled with the 3Al anti-T cell monoclonal antibody.” Eur J Immunol 12, no. 6 (June 1982): 474–79. https://doi.org/10.1002/eji.1830120605.Full Text Link to Item
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“Lymphomatoid granulomatosis.” N Engl J Med 306, no. 21 (May 27, 1982): 1294–95.Link to Item
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Haynes, B. F., L. L. Hensley, and B. V. Jegasothy. “Differentiation of human T lymphocytes: II. Phenotypic difference in skin and blood malignant T-cells in cutaneous T-cell lymphoma.” J Invest Dermatol 78, no. 4 (April 1982): 323–26. https://doi.org/10.1111/1523-1747.ep12507406.Full Text Link to Item
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Jackson, R. A., M. A. Morris, B. F. Haynes, and G. S. Eisenbarth. “Increased circulating Ia-antigen-bearing T cells in type I diabetes mellitus.” N Engl J Med 306, no. 13 (April 1, 1982): 785–88. https://doi.org/10.1056/NEJM198204013061305.Full Text Link to Item
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Haynes, B. F., D. L. Dowell, L. L. Hensley, I. Gore, and R. S. Metzgar. “Human T cell antigen expression by primate T cells.” Science 215, no. 4530 (January 15, 1982): 298–300. https://doi.org/10.1126/science.6171885.Full Text Link to Item
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Fauci, A. S., B. F. Haynes, J. Costa, P. Katz, and S. M. Wolff. “Lymphomatoid Granulomatosis. Prospective clinical and therapeutic experience over 10 years.” N Engl J Med 306, no. 2 (January 14, 1982): 68–74. https://doi.org/10.1056/NEJM198201143060203.Full Text Link to Item
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FAUCI, A. S., J. COSTA, B. F. HAYNES, P. KATZ, and S. M. WOLFF. “LYMPHOMATOID GRANULOMATOSIS - REPLY.” New England Journal of Medicine 306, no. 21 (January 1, 1982): 1295–1295.Link to Item
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GOLIGHTLY, M. G., B. F. HAYNES, C. P. BRANDT, and H. S. KOREN. “PHENOTYPIC AND FUNCTIONAL-CHARACTERIZATION OF NATURAL-KILLER CELLS BY MONOCLONAL-ANTIBODIES.” Federation Proceedings 41, no. 3 (January 1, 1982): 804–804.Link to Item
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HAYNES, B. F., G. S. EISENBARTH, and R. S. METZGAR. “PHYLOGENY AND ONTOGENY OF HUMAN THYMUS ANTIGENS DEFINED BY MONOCLONAL-ANTIBODIES.” Hybridoma 1, no. 2 (January 1, 1982): 185–185.Link to Item
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HAYNES, B. F., R. W. WARREN, R. H. BUCKLEY, J. E. MCCLURE, A. L. GOLDSTEIN, and G. S. EISENBARTH. “COMPLEX GANGLIOSIDES AS MARKERS OF THYMIC EPITHELIUM - DEMONSTRATION OF DEFECTS IN THYMIC EPITHELIUM STRUCTURE AND GANGLIOSIDE EXPRESSION IN SEVERE COMBINED IMMUNODEFICIENCY DISEASE.” Clinical Research 30, no. 2 (January 1, 1982): A350–A350.Link to Item
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Hooks, J. J., B. F. Haynes, B. Detrick-Hooks, L. F. Diehl, T. L. Gerrard, and A. S. Fauci. “Gamma (immune) interferon production by leukocytes from a patient with a TG cell proliferative disease.” Blood 59, no. 1 (January 1982): 198–201.Link to Item
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JACKSON, R., M. A. MORRIS, B. HAYNES, and G. S. EISENBARTH. “TYPE-I DIABETES-MELLITUS - IA POSITIVE T-CELLS, A REFLECTION OF DISEASE-ACTIVITY.” Clinical Research 30, no. 2 (January 1, 1982): A395–A395.Link to Item
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KADISON, P., R. JACKSON, N. RASSI, B. HAYNES, B. JEGASOTHY, and G. S. EISENBARTH. “THE BB RAT - SELECTIVE W3/25 T-CELL LYMPHOCYTOPENIA AND PROFOUND DEPRESSION OF MITOGEN RESPONSIVENESS.” Clinical Research 30, no. 2 (January 1, 1982): A396–A396.Link to Item
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OLSEN, E. A., B. V. JEGASOTHY, and B. F. HAYNES. “PARA-PSORIASIS EN PLAQUES - PHENOTYPIC ANALYSIS OF CUTANEOUS T-CELL INFILTRATES.” Journal of Investigative Dermatology 78, no. 4 (January 1, 1982): 337–337.Link to Item
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OLSEN, E. A., B. V. JEGASOTHY, and B. F. HAYNES. “PARA-PSORIASIS EN PLAQUES - PHENOTYPIC ANALYSIS OF CUTANEOUS T-CELL INFILTRATES.” Clinical Research 30, no. 2 (January 1, 1982): A600–A600.Link to Item
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EISENBARTH, G. S., M. J. TELEN, C. PETERSON, T. REIMAN, and B. F. HAYNES. “CHARACTERIZATION OF A NOVEL CELL-SURFACE GLYCOPROTEIN COEXPRESSED ON CELLS BEARING THE INSULIN-RECEPTOR AND SELECTIVELY EXPRESSED ON PANCREATIC-ISLET CELLS.” Clinical Research 30, no. 2 (January 1, 1982): A391–A391.Link to Item
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TELEN, M. J., G. S. EISENBARTH, and B. F. HAYNES. “CHARACTERIZATION AND DISTRIBUTION OF A LUTHERAN ERYTHROCYTE ANTIGEN AS DEFINED BY A MONOCLONAL-ANTIBODY.” Clinical Research 30, no. 2 (January 1, 1982): A331–A331.Link to Item
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Levine, M. N., J. W. Fay, N. H. Jones, R. S. Metzgar, and B. F. Haynes. “Phenotypic characterization of human bone marrow granulocyte-macrophage forming progenitor cells.” Blood 58, no. 5 (November 1981): 1047–49.Link to Item
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Jackson, R., N. Rassi, T. Crump, B. Haynes, and G. S. Eisenbarth. “The BB diabetic rat. Profound T-cell lymphocytopenia.” Diabetes 30, no. 10 (October 1981): 887–89. https://doi.org/10.2337/diab.30.10.887.Full Text Link to Item
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De Waele, M., S. Van Belle, W. Gepts, C. Thielemans, D. Schallier, and B. Van Camp. “A Lennert lymphoma with a helper-T-cell phenotype.” N Engl J Med 305, no. 14 (October 1, 1981): 831–32. https://doi.org/10.1056/NEJM198110013051413.Full Text Link to Item
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Haynes, B. F., M. Hemler, T. Cotner, D. L. Mann, G. S. Eisenbarth, J. L. Strominger, and A. S. Fauci. “Characterization of a monoclonal antibody (5E9) that defines a human cell surface antigen of cell activation.” J Immunol 127, no. 1 (July 1981): 347–51.Link to Item
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Haynes, B. F., R. S. Metzgar, J. D. Minna, and P. A. Bunn. “Phenotypic characterization of cutaneous T-cell lymphoma. Use of monoclonal antibodies to compare with other malignant T cells.” N Engl J Med 304, no. 22 (May 28, 1981): 1319–23. https://doi.org/10.1056/NEJM198105283042202.Full Text Link to Item
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Haynes, B. F., M. E. Hemler, D. L. Mann, G. S. Eisenbarth, J. Shelhamer, H. S. Mostowski, C. A. Thomas, J. L. Strominger, and A. S. Fauci. “Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes.” J Immunol 126, no. 4 (April 1981): 1409–14.Link to Item
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Schooley, R. T., B. F. Haynes, J. Grouse, C. Payling-Wright, A. S. Fauci, and R. Dolin. “Development of suppressor T lymphocytes for Epstein-Barr virus-induced B-lymphocyte outgrowth during acute infectious mononucleosis: assessment by two quantitative systems.” Blood 57, no. 3 (March 1981): 510–17.Link to Item
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Haynes, B. F., A. Pikus, M. Kaiser-Kupfer, and A. S. Fauci. “Successful treatment of sudden hearing loss in Cogan's syndrome with corticosteroids.” Arthritis Rheum 24, no. 3 (March 1981): 501–3. https://doi.org/10.1002/art.1780240308.Full Text Link to Item
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Haynes, B. F., P. Bunn, D. Mann, C. Thomas, G. S. Eisenbarth, J. Minna, and A. S. Fauci. “Cell surface differentiation antigens of the malignant T cell in Sezary syndrome and mycosis fungoides.” J Clin Invest 67, no. 2 (February 1981): 523–30. https://doi.org/10.1172/JCI110062.Full Text Link to Item
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HAYNES, B. F. “DIFFERENTIATION PATHWAYS OF HUMAN-LYMPHOCYTES - USE OF MONOCLONAL-ANTIBODIES AND MALIGNANT T-CELLS AS INVESTIGATIVE PROBES.” Immunobiology 159, no. 1–2 (January 1, 1981): 14–14.Link to Item
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HAYNES, B. F., C. W. OLANOW, G. S. EISENBARTH, and A. D. ROSES. “CORRECTION OF IMMUNOREGULATORY T-CELL IMBALANCE IN MYASTHENIA-GRAVIS FOLLOWING THYMECTOMY.” Clinical Research 29, no. 2 (January 1, 1981): A430–A430.Link to Item
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HAYNES, B. F., M. HEMLER, D. L. MANN, G. S. EISENBARTH, J. L. STROMINGER, and A. S. FAUCI. “CHARACTERIZATION OF A MONOCLONAL ANTIBODY(5E9) WHICH DEFINES A NOVEL HUMAN CELL-SURFACE ANTIGEN OF CELL ACTIVATION.” Clinical Research 29, no. 2 (January 1, 1981): A368–A368.Link to Item
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HAYNES, B. F., and R. S. METZGAR. “A LENNERT LYMPHOMA WITH A HELPER-T-CELL PHENOTYPE - REPLY.” New England Journal of Medicine 305, no. 14 (January 1, 1981): 832–832.Link to Item
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Haynes, B. F. “Human T lymphocyte antigens as defined by monoclonal antibodies.” Immunol Rev 57 (1981): 127–61. https://doi.org/10.1111/j.1600-065x.1981.tb00445.x.Full Text Link to Item
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Haynes, B. F., and A. S. Fauci. “Acknowledgment to Dartmouth Medical Center.” Arthritis &Amp; Rheumatism 24, no. 12 (January 1, 1981): 1587–1587. https://doi.org/10.1002/art.1780241223.Full Text
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Hooks, J. J., B. F. Haynes, B. Detrick-Hooks, L. F. Diehl, T. L. Gerrard, and A. S. Fauci. “Gamma (immune) interferon produced by leukocytes from a patients with a T cell proliferation disease.” Trans Assoc Am Physicians 94 (1981): 198–203.Link to Item
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Moretta, A., M. C. Mingari, B. F. Haynes, R. P. Sekaly, L. Moretta, and A. S. Fauci. “Phenotypic characterization of human cytolytic T lymphocytes in mixed lymphocyte culture.” J Exp Med 153, no. 1 (January 1, 1981): 213–18. https://doi.org/10.1084/jem.153.1.213.Full Text Link to Item
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Schooley, R. T., B. F. Haynes, C. R. Payling-Wright, J. E. Grouse, R. Dolin, and A. S. Fauci. “Mechanism of Epstein-Barr virus-induced human B-lymphocyte activation.” Cell Immunol 56, no. 2 (December 1980): 518–25. https://doi.org/10.1016/0008-8749(80)90126-4.Full Text Link to Item
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Haynes, B. F., M. I. Kaiser-Kupfer, P. Mason, and A. S. Fauci. “Cogan syndrome: studies in thirteen patients, long-term follow-up, and a review of the literature.” Medicine (Baltimore) 59, no. 6 (November 1980): 426–41.Link to Item
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Haynes, B. F., D. L. Mann, M. E. Hemler, J. A. Schroer, J. H. Shelhamer, G. S. Eisenbarth, J. L. Strominger, C. A. Thomas, H. S. Mostowski, and A. S. Fauci. “Characterization of a monoclonal antibody that defines an immunoregulatory T cell subset for immunoglobulin synthesis in humans.” Proc Natl Acad Sci U S A 77, no. 5 (May 1980): 2914–18. https://doi.org/10.1073/pnas.77.5.2914.Full Text Link to Item
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Eisenbarth, G. S., B. F. Haynes, J. A. Schroer, and A. S. Fauci. “Production of monoclonal antibodies reacting with peripheral blood mononuclear cell surface differentiation antigens.” J Immunol 124, no. 3 (March 1980): 1237–44.Link to Item
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EISENBARTH, G. S., B. F. HAYNES, B. RANKIN, and A. FAUCI. “RAPID ASSAY AND PURIFICATION OF HUMAN CELL-SURFACE DIFFERENTIATION ANTIGENS REACTING WITH MONOCLONAL-ANTIBODIES.” Clinical Research 28, no. 2 (January 1, 1980): A345–A345.Link to Item
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HAYNES, B. F., D. L. MANN, P. KATZ, G. S. EISENBARTH, M. HIMMLER, J. L. STROMINGER, and A. S. FAUCI. “USE OF MONOCLONAL-ANTIBODY (3A1) TO CHARACTERIZE FUNCTIONAL HUMAN T-CELL SUBSETS.” Clinical Research 28, no. 2 (January 1, 1980): A348–A348.Link to Item
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HAYNES, B. F., G. E. EISENBARTH, D. MANN, C. THOMAS, J. SHELHAMER, J. A. SCHROER, and A. S. FAUCI. “CHARACTERIZATION OF A MONOCLONAL-ANTIBODY (3A1) WHICH DEFINES THE HUMAN HELPER T-CELL.” Federation Proceedings 39, no. 3 (January 1, 1980): 1163–1163.Link to Item
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Haynes, B. F., P. Katz, and A. S. Fauci. “Immune responses of human lymphocytes in vitro.” Prog Clin Immunol 4 (1980): 23–62.Link to Item
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Eisenbarth, G. S., R. B. Rankin, B. F. Haynes, and A. S. Fauci. “A visual assay to monitor purification of cell surface antigens reacting with monoclonal antibodies.” J Immunol Methods 39, no. 4 (1980): 387–92. https://doi.org/10.1016/0022-1759(80)90239-2.Full Text Link to Item
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Conn, D. L., and J. V. Donadio. “Treatment of vasculitis with cyclophosphamide.” N Engl J Med 301, no. 20 (November 15, 1979): 1122. https://doi.org/10.1056/NEJM197911153012015.Full Text Link to Item
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Haynes, B. F., G. S. Eisenbarth, and A. S. Fauci. “Human lymphocyte antigens: production of a monoclonal antibody that defines functional thymus-derived lymphocyte subsets.” Proc Natl Acad Sci U S A 76, no. 11 (November 1979): 5829–33. https://doi.org/10.1073/pnas.76.11.5829.Full Text Link to Item
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Haynes, B. F., R. T. Schooley, C. R. Payling-Wright, J. E. Grouse, R. Dolin, and A. S. Fauci. “Emergence of suppressor cells of immunoglobulin synthesis during acute Epstein-Barr virus-induced infectious mononucleosis.” J Immunol 123, no. 5 (November 1979): 2095–2101.Link to Item
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Katz, P., D. W. Alling, B. F. Haynes, and A. S. Fauci. “Association of Wegener's granulomatosis with HLA-B8.” Clin Immunol Immunopathol 14, no. 2 (October 1979): 268–70. https://doi.org/10.1016/0090-1229(79)90150-8.Full Text Link to Item
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Haynes, B. F., and A. S. Fauci. “Activation of human B lymphocytes. XIII. Characterization of multiple populations of naturally occurring immunoregulatory cells of polyclonally induced in vitro human B cell function.” J Immunol 123, no. 3 (September 1979): 1289–98.Link to Item
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Fauci, A. S., P. Katz, B. F. Haynes, and S. M. Wolff. “Cyclophosphamide therapy of severe systemic necrotizing vasculitis.” N Engl J Med 301, no. 5 (August 2, 1979): 235–38. https://doi.org/10.1056/NEJM197908023010503.Full Text Link to Item
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Dimitriu, A., B. F. Haynes, and A. S. Fauci. “Activation of human B lymphocytes. XIV. Characterization of the precursor of the pokeweed mitogen-induced anti-sheep red blood cell plaque-forming cell.” J Immunol 123, no. 2 (August 1979): 890–95.Link to Item
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Haynes, B. F., P. Katz, and A. S. Fauci. “Mechanisms of corticosteroid action on lymphocyte subpopulations. V. Effects of in vivo hydrocortisone on the circulatory kinetics and function of naturally occuring and mitogen-induced suppressor cells in man.” Cell Immunol 44, no. 1 (April 1979): 169–78. https://doi.org/10.1016/0008-8749(79)90037-6.Full Text Link to Item
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Haynes, B. F., and A. S. Fauci. “Mechanisms of corticosteroid action on lymphocyte subpopulations. IV. Effects of in vitro hydrocortisone on naturally occuring and mitogen-induced suppressor cells in man.” Cell Immunol 44, no. 1 (April 1979): 157–68. https://doi.org/10.1016/0008-8749(79)90036-4.Full Text Link to Item
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Haynes, B. F., R. T. Schooley, J. E. Grouse, C. R. Payling-Wright, R. Dolin, and A. S. Fauci. “Characterization of thymus-derived lymphocyte subsets in acute Epstein-Barr virus-induced infectious mononucleosis.” J Immunol 122, no. 2 (February 1979): 699–702.Link to Item
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Pont, A., L. Y. Yamaguchi, and M. G. DeLada. “Cyclophosphamide treatment of diabetes insipidus in Wegener's granulomatosis.” N Engl J Med 300, no. 5 (February 1, 1979): 259–60. https://doi.org/10.1056/NEJM197902013000515.Full Text Link to Item
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Fauci, A. S., P. Katz, B. F. Haynes, and S. M. Wolff. “Dramatic remissions in severe systemic necrotizing vasculitis (SNV) with cyclophosphamide (CY) therapy.” Clinical Research 27, no. 2 (January 1, 1979).
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Katz, P., B. F. Haynes, and A. S. Fauci. “Lack of generation of killer cells in the mixed lymphocyte reaction between mitogen-stimulated and unstimulated autologous lymphocytes.” J Immunol 121, no. 5 (November 1978): 1998–2001.Link to Item
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Fauci, A. S., B. Haynes, and P. Katz. “The spectrum of vasculitis: clinical, pathologic, immunologic and therapeutic considerations.” Ann Intern Med 89, no. 5 Pt 1 (November 1978): 660–76. https://doi.org/10.7326/0003-4819-89-5-660.Full Text Link to Item
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Haynes, B. F., and A. S. Fauci. “Diabetes insipidus associated with Wegener's granulomatosis successfully treated with cyclophosphamide.” N Engl J Med 299, no. 14 (October 5, 1978): 764. https://doi.org/10.1056/NEJM197810052991406.Full Text Link to Item
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Fauci, A. S., A. D. Steinberg, B. F. Haynes, and G. Whalen. “Immunoregulatory aberrations in systemic lupus erythematosus.” J Immunol 121, no. 4 (October 1978): 1473–79.Link to Item
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Kaiser-Kupfer, M. I., K. K. Mittal, L. A. Del Valle, and B. F. Haynes. “The HLA antigens in Cogan's syndrome.” Am J Ophthalmol 86, no. 3 (September 1978): 314–16. https://doi.org/10.1016/0002-9394(78)90231-3.Full Text Link to Item
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Haynes, B. F., and A. S. Fauci. “Activation of human B lymphocytes. X. Heterogeneity of concanavalin A-generated suppressor cells of the pokeweed mitogen-induced plaque-forming cell response of human peripheral blood lymphocytes.” J Immunol 121, no. 2 (August 1978): 559–65.Link to Item
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Katz, P., B. F. Haynes, and A. S. Fauci. “Alteration of T-lymphocyte subpopulations in sarcoidosis.” Clin Immunol Immunopathol 10, no. 3 (July 1978): 350–54. https://doi.org/10.1016/0090-1229(78)90192-7.Full Text Link to Item
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Kaiser-Kupfer, M. I., L. A. Del Valle, K. K. Mittal, and B. F. Haynes. “HLA and Cogan's syndrome.” N Engl J Med 298, no. 19 (May 11, 1978): 1094–95. https://doi.org/10.1056/nejm197805112981926.Full Text Link to Item
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Hunninghake, G. W., B. F. Haynes, J. E. Parrillo, and A. S. Fauci. “Comparison of the relative cytotoxic effector cell capabilities and the proportions of cells bearing various surface markers in human tonsil and peripheral blood mononuclear cells.” Clin Exp Immunol 32, no. 1 (April 1978): 186–91.Link to Item
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Haynes, B. F., and A. S. Fauci. “Activation of human B lymphocytes. VI. Immunoregulation of antibody production by mitogen-induced and naturally occurring cells in normal individuals.” Cell Immunol 36, no. 2 (March 15, 1978): 294–302. https://doi.org/10.1016/0008-8749(78)90273-3.Full Text Link to Item
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Haynes, B. F., and A. S. Fauci. “The differential effect of in vivo hydrocortisone on the kinetics of subpopulations of human peripheral blood thymus-derived lymphocytes.” J Clin Invest 61, no. 3 (March 1978): 703–7. https://doi.org/10.1172/JCI108982.Full Text Link to Item
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Haynes, B. F., and A. S. Fauci. “Activation of human B lymphocytes. V. Kinetics and mechanisms of suppression of plaque-forming cell responses by concanavalin A-generated suppressor cells.” J Immunol 120, no. 3 (March 1978): 700–708.Link to Item
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Haynes, B. F., and A. S. Fauci. “The effect of in vivo and in vitro hydrocortisone (HC) on human suppressor cells (SC).” Clinical Research 26, no. 3 (January 1, 1978).
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Haynes, B. F., and A. S. Fauci. “Differential effects of in vivo hydrocortisone on human T cell subpopulations.” Journal of Allergy and Clinical Immunology 61, no. 3 (January 1, 1978).
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Vermess, M., B. F. Haynes, A. S. Fauci, and S. M. Wolff. “Computer assisted tomography of orbital lesions in Wegener's granulomatosis.” J Comput Assist Tomogr 2, no. 1 (January 1978): 45–48. https://doi.org/10.1097/00004728-197801000-00006.Full Text Link to Item
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Haynes, B. F., M. L. Fishman, A. S. Fauci, and S. M. Wolff. “The ocular manifestations of Wegener's granulomatosis. Fifteen years experience and review of the literature.” Am J Med 63, no. 1 (July 1977): 131–41. https://doi.org/10.1016/0002-9343(77)90125-5.Full Text Link to Item
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Haynes, B. F., and A. S. Fauci. “Activation of human B lymphocytes. III. Concanavalin A-induced generation of suppressor cells of the plaque-forming cell response of normal human B lymphocytes.” J Immunol 118, no. 6 (June 1977): 2281–87.Link to Item
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Haynes, B. F., and A. S. Fauci. “Concanavalin A induced generation of suppressor cells of the plaque forming cell response of normal human B lymphocytes.” Federation Proceedings 36, no. 3 (January 1, 1977).
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Haynes, B. F., R. Wright, and J. P. McCracken. “Mollaret meningitis. A report of three cases.” Jama 236, no. 17 (October 25, 1976): 1967–69. https://doi.org/10.1001/jama.236.17.1967.Full Text Link to Item
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Sherwood, G. K., B. F. Haynes, and W. F. Rosse. “Hemolytic transfusion reactions caused by failure of commercial antiglobulin reagents to detect complement.” Transfusion 16, no. 5 (1976): 417–20. https://doi.org/10.1046/j.1537-2995.1976.16577039295.x.Full Text Link to Item
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Sexton, D. J., and B. Haynes. “Bird-mite infestation in a university hospital.” Lancet 1, no. 7904 (February 22, 1975): 445. https://doi.org/10.1016/s0140-6736(75)91506-8.Full Text Link to Item
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Haynes, B. F., W. R. Cheek, and A. A. Mintz. “Treatment of meningomyelocele in indigent and nonindigent patients.” Am J Dis Child 127, no. 2 (February 1974): 182–86. https://doi.org/10.1001/archpedi.1974.02110210032004.Full Text Link to Item
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Haynes, B. F. “A brief review. Poststreptococcal glomerulonephritis.” Tex Med 69, no. 2 (February 1973): 60–68.Link to Item
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Book Sections
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McCallum, R. M., E. W. St.Clair, and B. F. Haynes. “Cogan's syndrome.” In Inflammatory Diseases of Blood Vessels, 491–509, 2016.
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Haynes, B. F., K. O. Saunders, G. Kelsoe, J. R. Mascola, and G. J. Nabel. “The Cellular and Molecular Biology of HIV-1 Broadly Neutralizing Antibodies.” In Molecular Biology of B Cells: Second Edition, 441–61, 2015. https://doi.org/10.1016/B978-0-12-397933-9.00024-2.Full Text
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Haynes, B. F. “Serendipity and Stamina: Staying the course.” In Medicine Science and Dreams: The Making of Physician-Scientists, 143–58, 2011. https://doi.org/10.1007/978-90-481-9538-1_10.Full Text
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McCallum, R. M., E. W. St Clair, and B. F. Haynes. “Cogan’s syndrome.” In Inflammatory Diseases of Blood Vessels, 491–509, 2000. https://doi.org/10.1201/b14012.Full Text
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Other Articles
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Zhu, Z., H. R. Qin, W. Chen, Q. Zhao, X. Shen, R. Schutte, Y. Wang, et al. “Erratum to Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies [Journal of Virology, 85, 21, (2011) 11401-11408] DOI: 10.1128/JVI.05312-11.” Journal of Virology, December 1, 2013. https://doi.org/10.1128/JVI.02726-13.Full Text
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Haynes, B. F., L. P. Hale, K. J. Weinhold, D. D. Patel, H. X. Liao, P. B. Bressler, D. M. Jones, et al. “Analysis of the adult thymus in reconstitution of T lymphocytes in HIV-1 infection.” J Clin Invest, March 15, 1999. https://doi.org/10.1172/jci5201e1.Full Text Link to Item
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Conference Papers
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Eslamizar, L., C. Petrovas, D. J. Leggat, K. Furr, M. L. Lifton, G. Levine, S. Ma, et al. “Recombinant MVA-prime elicits neutralizing antibody responses by inducing antigen-specific B cells in the germinal center.” In Npj Vaccines, Vol. 6, 2021. https://doi.org/10.1038/s41541-020-00277-1.Full Text
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LaBranche, Celia, Rahul Basu, Barton Haynes, David Montefiori, and Harriet Robinson. “Characterization of the CD4BS-specific neutralizing antibody response in a macaque with autologous tier 2 neutralizing antibodies.” In Journal of Medical Primatology, 48:296–296. WILEY, 2019.Link to Item
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Robinson, H. L., R. Basu, J. A. Schwartz, M. J. Hauser, C. T. Demarco, A. L. DeVico, B. F. Haynes, and H. Andersen. “Protein-supplemented DNA/MVA vaccines: Preclinical immunogenicity and protection for transmitted/founder (B.63521 Delta 11mutC) and CD4-induced gp120 (rhFLSC) proteins.” In Journal of the International Aids Society, 22:19–20. JOHN WILEY & SONS LTD, 2019.Link to Item
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Andrabi, Raiees, Chuancang Jiang, Jinsong Zhang, Amanda Newman, Ge Song, Jesper Pallesen, Gavin Gegg, et al. “Vaccine Induction of V2 Apex-directed, Cross-reactive Neutralizing Antibodies in CH01 UCA "HC Only" Knock-in Mice.” In Aids Research and Human Retroviruses, 34:121–121. MARY ANN LIEBERT, INC, 2018.Link to Item
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Andrabi, Raiees, Jesper Pallesen, Joel Allen, Ge Song, Jinsong Zhang, Natalia de Val, Gavin Gegg, et al. “Chimpanzee SIV Envelope-derived Trimer Guides an Immunofocused HIV Cross-neutralizing Ab Response in V2-apex bnAb UCA Expressing Knock-in Mice.” In Aids Research and Human Retroviruses, 34:60–60. MARY ANN LIEBERT, INC, 2018.Link to Item
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Astronomo, Rena, Katharine Westerberg, Lamar Fleming, Greg Mize, Tiffany Hensley-McBain, Stephen DeRosa, Christina Ochsenbauer, et al. “Neutralization Potency Can Account for the Majority of Antibody-mediated Protection Observed in ex vivo Vaginal Explant Models of Early HIV Infection.” In Aids Research and Human Retroviruses, 34:302–302. MARY ANN LIEBERT, INC, 2018.Link to Item
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Behrens, Shay, Celia C. LaBranche, Tongqing Zhou, Kevin Wiehe, Mattia Bonsignori, Quentin J. Sattentau, Amanda Eaton, et al. “Germline-targeting and Reverse Engineering to Elicit CH235.12 Lineage bNAbs.” In Aids Research and Human Retroviruses, 34:116–116. MARY ANN LIEBERT, INC, 2018.Link to Item
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Blasi, Maria, Erich Baker, Elizabeth Brunner, Celia Labranche, David Montefiori, Kevin Saunders, Anthony Moody, et al. “Therapeutic Vaccination With a Combination of IDLV-SIV-Gag and IDLV-PGT121 Results in Prolonged Virus Control in Chronically SHIV-infected Macaques.” In Aids Research and Human Retroviruses, 34:50–50. MARY ANN LIEBERT, INC, 2018.Link to Item
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Bonsignori, Mattia, Eric Scott, Kevin Wiehe, David Easterhoff, S Munir Alam, Kwan-Ki Hwang, David C. Montefiori, et al. “Dual Maturation Pathways from the Unmutated Common Ancestor of HIV-1 Envelope Broadly Neutralizing Antibodies Overcome Glycan Barriers.” In Aids Research and Human Retroviruses, 34:111–111. MARY ANN LIEBERT, INC, 2018.Link to Item
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Crooks, Ema, Samantha Grimley, Michelle Cully, Keiko Osawa, Gillian Dekkers, Kevin Saunders, Sebastian Ramisch, et al. “Glycoengineering HIV-1 Env Creates "Supercharged" and "Hybrid" Glycans to Increase Neutralizing Antibody Potency, Breadth and Saturation.” In Aids Research and Human Retroviruses, 34:113–113. MARY ANN LIEBERT, INC, 2018.Link to Item
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Frahm, Nicole, Andrew Fiore-Gartland, Harman Malhi, Lindsey R. Baden, Stephen R. Walsh, Kristen W. Cohen, Marnie Elizaga, et al. “Increased Breadth of T-cell Responses After Mosaic HIV Vaccination in Humans (HVTN 106).” In Aids Research and Human Retroviruses, 34:31–31. MARY ANN LIEBERT, INC, 2018.Link to Item
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Kimpel, Janine, C Anika Bresk, Tamara Hofer, Sarah Wilmschen, Marina Krismer, Anja Beierfuss, Gregory Effantin, et al. “HIV Neutralizing Antibodies Induced by Native-like Envelope Trimers Incorporated Into a Rhabdoviral Vector Vaccine.” In Aids Research and Human Retroviruses, 34:324–324. MARY ANN LIEBERT, INC, 2018.Link to Item
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Li, Hui, Ryan Roark, Shuyi Wang, Fang-Hua Lee, Wenge Ding, Alex Murphy, Juliette Rando, et al. “New SHIV Models of bNAb Elicitation and Env-Ab Coevolution.” In Aids Research and Human Retroviruses, 34:21–21. MARY ANN LIEBERT, INC, 2018.Link to Item
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Peachman, Kristina, David Easterhoff, Siriwat Akapirat, Supachai Rerks-Ngarm, Punnee Pittisuttithum, Sorachai Nitayaphan, Sanjay Phogat, et al. “Prolonged Intervals Between Boosts Induces High Magnitude Transient V2-specific Functional Antibodies That Inhibit the Binding of V2 to alpha 4 beta 7 Integrin.” In Aids Research and Human Retroviruses, 34:127–127. MARY ANN LIEBERT, INC, 2018.Link to Item
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Tuyishime, Marina, Carolina Garrido, Shalini Jha, Anthony DeVico, Barton Haynes, David Margolis, and Guido Ferrari. “Recognition and Elimination of HIV-1-infected Cells by ADCC-mediating mAbs for Prevention and Treatment of HIV-1 Infection.” In Aids Research and Human Retroviruses, 34:126–126. MARY ANN LIEBERT, INC, 2018.Link to Item
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Verkoczy, Laurent, Chuancang Jiang, Raiees Andrabi, Jinsong Zhang, Amanda Newman, Devin Sok, Ge Song, et al. “Mechanistic Insights Into Vaccine Induction of V2 Apex-directed, Heterologous Tier 2 Neutralizing Responses in CH103 UCA Knock-in Mice.” In Aids Research and Human Retroviruses, 34:110–110. MARY ANN LIEBERT, INC, 2018.Link to Item
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Wiehe, Kevin, Kevin O. Saunders, Todd Bradley, Willam J. Faison, Connor Hart, Cindy Bowman, Ashley Trama, et al. “Targeted Selection of an Improbable HIV-1 Antibody Mutation Critical for Broadly Neutralizing Reactivity With a Designed Immunogen.” In Aids Research and Human Retroviruses, 34:58–58. MARY ANN LIEBERT, INC, 2018.Link to Item
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Williams, LaTonya, Matthew Zirui Tay, Xiaoying Shen, Sheetal Sawant, Lindsay Dahora, Nicole Yates, David Easterhoff, et al. “Delayed and Repetitive Boosting of RV144 Vaccinees Improves Antiviral Immunity Associated With Correlates of HIV-1 Infection Risk.” In Aids Research and Human Retroviruses, 34:88–88. MARY ANN LIEBERT, INC, 2018.Link to Item
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Williams, Wilton Bryan, R Ryan Meyerhoff, Hui Li, Priyamvada Acharya, Guillaume B. E. Stewart-Jones, Kevin Wiehe, Thomas B. Kepler, et al. “Macaque SHIV Induction of 2G12-like Broadly Neutralizing Antibodies.” In Aids Research and Human Retroviruses, 34:38–38. MARY ANN LIEBERT, INC, 2018.Link to Item
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Madani, N., A. Princiotto, L. Mach, J. Richard, B. Hora, C. Zhao, T. Bradley, et al. “A CD4-mimetic compound enhances vaccine efficacy against stringent immunodeficiency virus challenge.” In Journal of the International Aids Society, 21:1–1. JOHN WILEY & SONS LTD, 2018.Link to Item
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Ferrari, Guido, Jeffrey Nordstrom, Scott Koenig, Julia Sung, David Margolis, and Barton Haynes. “A-102 Antibody binding to HIV-1 infected cells as mechanism for treatment of HIV infection.” In Jaids Journal of Acquired Immune Deficiency Syndromes, 77:33–33. Ovid Technologies (Wolters Kluwer Health), 2018. https://doi.org/10.1097/01.qai.0000532483.69631.d6.Full Text
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Li, Hui, Wilton Williams, Mattia Bonsignori, Shuyi Wang, Wenge Ding, Fang-Hau Lee, Maho Okumura, et al. “Molecular patterns of SHIV Env-Ab coevolution in rhesus macaques recapitulate HIV-1 Env-Ab co-evolution in humans infected by HIV-1 strains bearing homologous Envs.” In Journal of Medical Primatology, 46:174–75. WILEY, 2017.Link to Item
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Li, Hui, Wilton Williams, Mattia Bonsignori, Shuyi Wang, Wenge Ding, Fang-Hau Lee, Maho Okumura, et al. “Molecular patterns of SHIV Env-Ab coevolution in rhesus macaques recapitulate HIV-1 Env-Ab co-evolution in humans infected by HIV-1 strains bearing homologous envs.” In Journal of Medical Primatology, 46:206–7. WILEY, 2017.Link to Item
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Doria-Rose, Nicole A., Shelly Krebs, Wiliam Law, Syna Gift, Agnes Chenine, Morgane Rolland, M Anthony Moody, et al. “HIV-1 MPER-directed Broadly Neutralizing Antibodies from an Acute-infection Cohort RV217 Subject.” In Aids Research and Human Retroviruses, 32:36–36. MARY ANN LIEBERT, INC, 2016.Link to Item
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Duan, Hongying, Ming Tian, Cheng Cheng, Xuejun Chen, Hwei-Ling Cheng, Brandon J. Dekosky, M Gordon Joyce, et al. “Selective Activation of VRC01-class Germline Antibodies in Knock-in Mice with Diverse Precursor Repertoires.” In Aids Research and Human Retroviruses, 32:124–124. MARY ANN LIEBERT, INC, 2016.Link to Item
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Francica, Joseph, Geoffrey Lynn, Richard Laga, Baptiste Aussedat, Ryan Meyerhoff, Munir Alam, Samuel Danishefsky, Barton Haynes, and Robert Seder. “Synthetic Biocompatible Polymers Are an Effective Delivery Platform That Elicits Potent Antibody Responses Against HIV-1 Glycopeptide Immunogens.” In Aids Research and Human Retroviruses, 32:221–221. MARY ANN LIEBERT, INC, 2016.Link to Item
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Haynes, Barton. “Initiation of Neutralizing Antibody B Cell Lineages by HIV Vaccine Candidates.” In Aids Research and Human Retroviruses, 32:18–18. MARY ANN LIEBERT, INC, 2016.Link to Item
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Kasturi, Sudhir, Ata Ur Rasheed, Colin Havenar-Daughton, Matthew Pham, Yevgeniy Kovalenkov, Sanjeev Gumber, Matthew Johnson, et al. “Role of Adjuvants in Enhancing Durability of HIV Vaccine Responses by Inducing Potent Germinal Centers and Plasma Cell Responses.” In Aids Research and Human Retroviruses, 32:30–30. MARY ANN LIEBERT, INC, 2016.Link to Item
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Madani, Navid, Amy Princiotto, David Easterhoff, Todd Bradley, Kan Luo, M Anthony Moody, Ganesh Phad, et al. “Prevention of Vaginal Transmission of Simian-Human Immunodeficiency Virus (SHIV) in Rhesus Monkeys by Small-molecule CD4-mimetic Compounds.” In Aids Research and Human Retroviruses, 32:129–129. MARY ANN LIEBERT, INC, 2016.Link to Item
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Reddy, Pradeep B. J., Sailaja Gangadhara, Traci Legere, Brenda Wehrle, Yevgeniy Kovalenkov, Lori M. Spicer, Madhavi Kaja, et al. “Effects of gp140 Protein Booster Immunizations to DNA/MVA SHIV Vaccine on Immunogenicity and Protection against Intravaginal Tier-2 SHIV Challenges.” In Aids Research and Human Retroviruses, 32:347–347. MARY ANN LIEBERT, INC, 2016.Link to Item
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Hora, B., N. Gulzar, Y. Chen, F. Cai, C. Su, K. Karagiannis, K. Smith, et al. “Streamlined quasispecies and subtype analysis of HIV-1 sequences generated by high-throughput sequencing using the high-performance integrated virtual environment (HIVE).” In Journal of the International Aids Society, Vol. 19. JOHN WILEY & SONS LTD, 2016.Open Access Copy Link to Item
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Finney, Joel T., Guang Yang, Masayuki Kuraoka, Takuya Nojima, Laurent Verkoczy, Daisuke Kitamura, Barton F. Haynes, and Garnett H. Kelsoe. “How Tolerance Shapes the Development of the HIV-1 Broadly Neutralizing Antibody 2F5.” In Journal of Immunology, Vol. 196. AMER ASSOC IMMUNOLOGISTS, 2016.Link to Item
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Haynes, Barton. “E-103 The pathway to HIV vaccine development.” In Jaids Journal of Acquired Immune Deficiency Syndromes, 71:57–57. Ovid Technologies (Wolters Kluwer Health), 2016. https://doi.org/10.1097/01.qai.0000479619.01903.4f.Full Text
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Michael, Nelson, Jerome Kim, Merlin Robb, Rasmi Thomas, and Barton Haynes. “E-102 Advances in Prophylactic HIV Vaccine Development.” In Jaids Journal of Acquired Immune Deficiency Syndromes, 67:59–59. Ovid Technologies (Wolters Kluwer Health), 2014. https://doi.org/10.1097/01.qai.0000456118.05548.46.Full Text
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Liao, L. H., A. M. Trama, W. B. Williams, M. A. Moody, N. Vandergrift, G. D. Tomaras, D. J. Marshall, et al. “Role of Intestinal Microbiota in Shaping the B Cell Repertoire in HIV Infection and Env Vaccination.” In Aids Res Hum Retroviruses, 30 Suppl 1:A19, 2014. https://doi.org/10.1089/aid.2014.5023a.abstract.Full Text Link to Item
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Moody, M. A., D. Easterhoff, T. C. Gurley, J. F. Whitesides, D. J. Marshall, A. Foulger, K. E. Lloyd, et al. “Induction of Antibodies with Long Variable Heavy Third Complementarity Determining Regions by Repetitive Boosting with AIDSVAX® B/E in RV144 Vaccinees.” In Aids Res Hum Retroviruses, 30 Suppl 1:A36, 2014. https://doi.org/10.1089/aid.2014.5057a.abstract.Full Text Link to Item
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Adamson, B., J. Fuchs, P. Johnson, B. Haynes, C. Sopher, D. Flood, and J. Kublin. “Development of an Early Stage Investigator Scholar Program for Preclinical Researchers.” In Aids Research and Human Retroviruses, 29:A33–A33. MARY ANN LIEBERT, INC, 2013.Link to Item
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Alam, M., M. S. Dennison, B. Aussedat, Y. Vohra, P. K. Park, A. Fernandez-Tejada, S. Stewart, et al. “High Affinity Recognition of Synthetic Glycopeptides by HIV-1 gp120 V1V2 Loop Broadly Neutralizing Antibodies and Their Unmutated Common Ancestors.” In Aids Research and Human Retroviruses, 29:A185–A185. MARY ANN LIEBERT, INC, 2013.Link to Item
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Bonsignori, M., K. Wiehe, R. M. Lynch, S. K. Grimm, D. M. Kozink, K. Hwang, J. A. Eudailey, et al. “Isolation and Characterization of an Autoreactive CD4bs Broad Neutralizing Antibody from a Chronic HIV-1 Controller with Systemic Lupus Erythematosus.” In Aids Research and Human Retroviruses, 29:A45–46. MARY ANN LIEBERT, INC, 2013.Link to Item
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Chen, Y., J. Zhang, H. Bouton-Verville, A. Newman, S. Xia, H. Liao, D. C. Montefiori, et al. “Lipid Components in MPER-Based Immunization Regimens Are Critical for Inducing Broadly Neutralizing Antibody Responses in 2F5 and 4E10 Knockin Mice.” In Aids Research and Human Retroviruses, 29:A20–A20. MARY ANN LIEBERT, INC, 2013.Link to Item
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Chuang, G., B. Zhang, K. Lloyd, J. Eudailey, J. Blinn, K. McKee, Y. Kwon, et al. “Eliminating Autoreactivity of Variants of Antibody VRC07 by Glycan Masking.” In Aids Research and Human Retroviruses, 29:A55–A55. MARY ANN LIEBERT, INC, 2013.Link to Item
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Gao, F., M. Bonsignori, H. Liao, A. Kumar, S. Xia, F. Cai, X. Lu, et al. “Multiple Pathways of HIV-1 Autologous Neutralizing Antibodies Cooperate to Drive CD4 Binding Site Broadly Neutralizing Antibody Responses.” In Aids Research and Human Retroviruses, 29:A186–A186. MARY ANN LIEBERT, INC, 2013.Link to Item
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Kunz, E., G. Fouda, C. Ho, J. Amos, L. Colvin, D. Montefiori, A. Martelli, et al. “Combined Mucosal and Systemic C.1086 Envelope Immunization of Lactating Monkeys Induces Potent IgA and Functional IgG Antibody Responses in Milk.” In Aids Research and Human Retroviruses, 29:A180–A180. MARY ANN LIEBERT, INC, 2013.Link to Item
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Mulky, A., H. Ding, Y. Mao, J. K. Wakefield, C. Ochsenbauer, M. Ray, A. Herschhorn, et al. “Exogenous Expression of HIV-1 Envelope Glycoprotein Trimer in Suspension Culture-Adapted HEK293 and CHO-K1 Cells.” In Aids Research and Human Retroviruses, 29:A190–91. MARY ANN LIEBERT, INC, 2013.Link to Item
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Nicely, N. I., K. Wiehe, T. B. Kepler, F. H. Jaeger, S. M. Dennison, H. Liao, S. M. Alam, et al. “Structural Analysis of the Unmutated Common Ancestor Antibodies of the HIV Envelope V2 Antibodies CH58 and CH59 Derived from RV144 Vaccinees.” In Aids Research and Human Retroviruses, 29:A167–68. MARY ANN LIEBERT, INC, 2013.Link to Item
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Pollara, J., M. Bonsignori, M. Moody, S. Alam, K. Hwang, T. C. Gurley, D. M. Kozink, et al. “Heterogeneity of Anti-V2 ADCC Ab Responses and Implications for Vaccine Development.” In Aids Research and Human Retroviruses, 29:A41–A41. MARY ANN LIEBERT, INC, 2013.Link to Item
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Prentice, H., D. E. Geraghty, G. D. Tomaras, Y. Fong, W. Nelson, G. H. Kijak, S. Zolla-Pazner, et al. “HLA Class II Genes Interact with the Immune Correlates from the RV144 Vaccine Efficacy Trial and Impact HIV-1 Acquisition.” In Aids Research and Human Retroviruses, 29:A178–A178. MARY ANN LIEBERT, INC, 2013.Link to Item
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Rolland, M., P. T. Edlefsen, R. Gottardo, D. C. Montefiori, S. Zolla-Pazner, A. Moody, L. H. Liao, et al. “Genetic and Immunological Evidence for a Role of Env-V3 Antibodies in the RV144 Trial.” In Aids Research and Human Retroviruses, 29:A168–A168. MARY ANN LIEBERT, INC, 2013.Link to Item
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Rudicell, R. S., A. Pegu, S. Ko, Y. Kwon, I. Georgiev, X. Wu, J. Zhu, et al. “Engineering a Next Generation VRC01-Like Antibody with Improved In Vitro and In Vivo Function.” In Aids Research and Human Retroviruses, 29:A48–49. MARY ANN LIEBERT, INC, 2013.Link to Item
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Sacha, C. R., N. Vandergrift, D. J. Marshall, T. C. Gurley, L. Stiegel, J. F. Whitesides, J. Friedman, et al. “Distinct VH Gene Usage and HIV Envelope Specificity of Colostrum and Peripheral B Cell Monoclonal Antibodies of HIV-Infected, Lactating African Women.” In Aids Research and Human Retroviruses, 29:A169–70. MARY ANN LIEBERT, INC, 2013.Link to Item
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Seaton, K., N. Yates, W. Williams, L. Liao, A. deCamp, Y. Fong, D. Montefiori, et al. “Human HIV-1 Vaccine Induced Antibody Durability and Env IgG3 Responses.” In Aids Research and Human Retroviruses, 29:A187–A187. MARY ANN LIEBERT, INC, 2013.Link to Item
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Trama, A. M., H. Liao, F. H. Jaeger, S. M. Alam, K. Wiehe, T. L. Jeffries, A. Foulger, et al. “Intestinal Commensal Bacteria Shape the Pre-transmission Antibody Repertoire to HIV-1 Infection.” In Aids Research and Human Retroviruses, 29:A105–A105. MARY ANN LIEBERT, INC, 2013.Link to Item
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Wieczorek, L., S. Krebs, V. Kalyanaraman, S. Whitney, G. R. Matyas, M. Rao, C. R. Alving, et al. “Comparable Antigenicity and Immunogenicity of Multimeric Forms of a Novel, Acute HIV-1 Subtype C Gp145 Envelope for Clinical Development.” In Aids Research and Human Retroviruses, 29:A30–A30. MARY ANN LIEBERT, INC, 2013.Link to Item
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Wiehe, K., D. Easterhoff, K. Luo, W. Williams, N. Vandergrift, E. Lloyd, C. Stolarchuk, et al. “Phylogenetic Conservation of a Dominant Antibody Light Chain HIV Env V2 Binding Motif in Human and rhesus Macaque Antibodies.” In Aids Research and Human Retroviruses, 29:A168–A168. MARY ANN LIEBERT, INC, 2013.Link to Item
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Williams, W. B., K. Jones, P. Liu, A. M. Trama, K. Seaton, M. A. Moody, N. Vandergrift, et al. “Antibody Repertoire Induced by the Multiclade (Env A, B, C) HIV-1 DNA Prime, rAd5 Boost VRC Vaccine.” In Aids Research and Human Retroviruses, 29:A9–A9. MARY ANN LIEBERT, INC, 2013.Link to Item
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Zhang, R., M. Moody, M. Alam, J. Yu, S. Santra, G. Kelsoe, S. Sekaran, et al. “Isolation of mAbs from Sorted Single B Cells by RT/PCR for Analysis of B Cell Responses to HIV-1 MPER Epitope in Vaccinated Rhesus Macaques.” In Aids Research and Human Retroviruses, 29:A30–A30. MARY ANN LIEBERT, INC, 2013.Link to Item
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Blasi, M., D. Negri, S. Santra, R. Parks, X. Shen, G. Tomaras, S. Permar, et al. “A Single Immunization with Integrase Defective Lentiviral Vector Expressing gp140 Induces Persistent and Functional Immune Response in Rhesus Monkeys.” In Aids Research and Human Retroviruses, 29:A161–A161. MARY ANN LIEBERT, INC, 2013.Link to Item
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Yang, Guang, T. Holl, Takuya Nojima, Laurent Verkoczy, M. Moody, Barton Haynes, Daisuke Kitamura, and Garnett Kelsoe. “The role of immunological tolerance in humoral responses to the 2F5 epitope of HIV-1.” In Journal of Immunology, Vol. 190. AMER ASSOC IMMUNOLOGISTS, 2013.Link to Item
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Haynes, Barton F., Thomas B. Kepler, Munir Alam, Stephen Harrison, Mattia Bonsignori, M Anthony Moody, Garnett Kelsoe, Laurent Verkoczy, and Hua-Xin Liao. “Analysis of Broad Neutralizing B Cell Lineages to Guide HIV-1 Immunogen Design.” In Jaids Journal of Acquired Immune Deficiency Syndromes, 62:54–54. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Zolla-Pazner, Susan, Hua-Xin Liao, Barton Haynes, Miroslaw K. Gorny, and Xiang-Peng Kong. “Identification of Three Distinct Epitope Regions in the V2 Portion of gp120.” In Jaids Journal of Acquired Immune Deficiency Syndromes, 62:52–52. LIPPINCOTT WILLIAMS & WILKINS, 2013.Link to Item
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Fouda, G. G., C. K. Cunningham, E. J. McFarland, W. Borkowsky, P. Muresan, B. E. Liebl, H. Liao, et al. “HIV-1 gp120 Vaccination Elicits a Robust and Durable Anti-V1/V2 IgG Response and Yet No HIV-1 Env-Specific IgA Response in HIV-Exposed Infants.” In Aids Research and Human Retroviruses, 29:A13–14, 2013.Link to Item
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Alexander, J., M. Gurwith, J. Mendy, L. Vang, D. Manayani, J. Avanzini, B. Guenther, et al. “Development of a HIV-1 vaccine using an orally-administered, replication-competent adenovirus serotype 4 vector expressing Env clade C glycoprotein.” In Retrovirology, Vol. 9. BIOMED CENTRAL LTD, 2012.Link to Item
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Bonsignori, M., J. Pollara, M. A. Moody, T. B. Kepler, X. Chen, T. C. Gurley, D. M. Kozink, et al. “Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial preferentially use the VH1 gene family.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p78.Full Text
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Fuchs, J. D., C. Morgan, P. Bart, N. Kochar, N. Frahm, E. Swann, P. Gilbert, et al. “DNA and recombinant adenovirus serotype 35 and 5 preventive HIV-1 vaccines with Env A inserts elicit cross-clade binding and V1V2 antibodies.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p136.Full Text
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Hertz, T., A. Gartland, H. Janes, S. Li, Y. Fong, G. D. Tomaras, D. Morris, et al. “T-cell based sieve analysis ties HLA A*02 to vaccine efficacy and IgA-C1 immune correlate in RV144 Thai trial.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o61.Full Text
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Liao, L., M. Bonsignori, K. Hwang, A. M. Moody, R. Park, S. Crawford, H. Chen, et al. “Design of an HIV Env antigen that binds with high affinity to antibodies against linear, conformational and broadly neutralizing epitopes within V1/V2.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o31.Full Text
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