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Hector Martinez-Wilson

Hector Martinez-Wilson

Assistant Professor of Anesthesiology
Anesthesiology, Regional

Selected Publications

The vibrio cholerae hybrid sensor kinase VieS contributes to motility and biofilm regulation by altering the cyclic diguanylate level.

Journal Article J Bacteriol · October 2008 Phosphorelay systems are important mediators of signal transduction during bacterial adaptation to new environments. Previously we described the vieSAB operon, encoding a putative three-protein component phosphorelay involved in regulating Vibrio cholerae ... Full text Link to item Cite

An in vivo expression technology screen for Vibrio cholerae genes expressed in human volunteers.

Journal Article Proc Natl Acad Sci U S A · November 13, 2007 In vivo expression technology (IVET) has been widely used to study gene expression of human bacterial pathogens in animal models, but has heretofore not been used in humans to our knowledge. As part of ongoing efforts to understand Vibrio cholerae pathogen ... Full text Link to item Cite

Second-generation recombination-based in vivo expression technology for large-scale screening for Vibrio cholerae genes induced during infection of the mouse small intestine.

Journal Article Infect Immun · February 2005 We have constructed an improved recombination-based in vivo expression technology (RIVET) and used it as a screening method to identify Vibrio cholerae genes that are transcriptionally induced during infection of infant mice. The improvements include the i ... Full text Link to item Cite

The ompU Paralogue vca1008 is required for virulence of Vibrio cholerae.

Journal Article J Bacteriol · August 2004 We made single and combined mutations in ompU, ompT, and the two putative porin genes vca1008 and vc0972. The fitness of the strains was tested in vitro and in the infant mouse model of intestinal infection. We also studied the transcriptional induction of ... Full text Link to item Cite

IL-2-induced CD4+ T-cell expansion in HIV-infected patients is associated with long-term decreases in T-cell proliferation.

Journal Article Blood · August 1, 2004 Administration of interleukin 2 (IL-2) leads to selective and sustained CD4+ T-cell expansions in patients infected with HIV. It has been hypothesized that persistent CD4+ T-cell proliferation is the primary mechanism maintaining these expansions. T-cell p ... Full text Link to item Cite

Long-term effects of intermittent interleukin 2 therapy in patients with HIV infection: characterization of a novel subset of CD4(+)/CD25(+) T cells.

Journal Article Blood · September 15, 2002 The long-term immunologic effects of intermittent interleukin 2 (IL-2) therapy were evaluated in a cross-sectional study by comparing 3 groups: HIV-seronegative volunteers, HIV-infected (HIV(+)) patients receiving highly active antiretroviral therapy (HAAR ... Link to item Cite