Overview
Dr. Tseng is a board-certified and fellowship-trained ophthalmologist in the diagnosis and treatment of glaucoma and cataracts. He is skilled in glaucoma laser and incisional surgical therapies. He also performs cataract surgery using the latest technology, such as femtosecond laser and multifocal intraocular lenses for multifocal vision correction.
Dr. Tseng is also a neuroscience, laboratory-trained clinician-scientist dedicated to both clinical and cutting-edge research into vision loss in glaucoma. The ultiĀmate research goal is to develop novel therapies and techniques for earlier detection of glaucoma and neurodegeneration. Dr. Tseng's research investigates molecular and cellular functions of optineurin, which is a gene associated with glaucoma, brain neurodegeneration, and Paget's disease of the bone. He is uncovering common disease mechanisms that leads to cell death in the eye, brain, and bone. Since the bone marrow is the primary source of stem cells, this work will reveal new insights into the development of regenerative and pharmacological therapies.Current Appointments & Affiliations
Associate Professor of Ophthalmology
·
2021 - Present
Ophthalmology, Glaucoma,
Ophthalmology
Recent Publications
Accelerated Epigenetic Aging Is Associated with Faster Glaucoma Progression: A DNA Methylation Study.
Journal Article Ophthalmology · December 21, 2024 PURPOSE: To investigate the association between epigenetic age acceleration and glaucoma progression. DESIGN: Retrospective cohort study. PARTICIPANTS: A total of 100 patients with primary open-angle glaucoma (POAG) with fast progression and 100 patients w ... Full text Link to item CiteAge-related effects of optineurin deficiency in the mouse eye.
Journal Article Vision Res · November 2024 Optineurin (OPTN) is a gene associated with familial normal tension glaucoma (NTG). While NTG involves intraocular pressure (IOP)-independent neurodegeneration of the visual pathway that progresses with age, how OPTN dysfunction leads to NTG remains unclea ... Full text Link to item CiteShort-term Detection of Fast Progressors in Glaucoma: The Fast Progression Assessment through Clustered Evaluation (Fast-PACE) Study.
Journal Article Ophthalmology · June 2024 PURPOSE: To evaluate the performance of an intensive, clustered testing approach in identifying eyes with rapid glaucoma progression over 6 months in the Fast Progression Assessment through Clustered Evaluation (Fast-PACE) Study. DESIGN: Prospective cohort ... Full text Link to item CiteRecent Grants
Respiratory Dysfunction in an Optineurin knock out ALS mouse model
ResearchCo Investigator · Awarded by National Institutes of Health · 2020 - 2022Comparison of Intraocular Pressure Measurements between Reichert Tono-Vera and Goldmann Tonometry
Clinical TrialPrincipal Investigator · Awarded by Reichert Technologies · 2020 - 2022Phase I Double Blind,Single & Multiple Ascending-Dose Study to Determine Effects of GDC-0134 in Patients w/ ALS
Clinical TrialPrincipal Investigator · Awarded by Wake Research Associates, LLC · 2017 - 2020View All Grants
Education, Training & Certifications
University of Pennsylvania ·
2002
M.D.
University of Pennsylvania ·
2001
Ph.D.