Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., University of Sao Paulo, Ribeirao Preto (Brazil) 1997
  • M.D., University of Sao Paulo, Ribeirao Preto (Brazil) 1986
• 

  Previous Appointments & Affiliations

  • Assistant Professor of Anesthesiology, Anesthesiology, Pediatrics, Anesthesiology 2009 - 2020
  • Visiting Associate in the Department of Anesthesiology, Anesthesiology, Pediatrics, Anesthesiology 2005 - 2009
  • Visiting Associate in the Department of Anesthesiology, Anesthesiology, Clinical Science Departments 2004 - 2005
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • King, Michael R., Steven J. Staffa, Paul A. Stricker, Carolina Pérez-Pradilla, Olivia Nelson, Hubert A. Benzon, Susan M. Goobie, and Susan M. Pediatric Craniofacial Collaborative Group. “Safety of antifibrinolytics in 6583 pediatric patients having craniosynostosis surgery: A decade of data reported from the multicenter Pediatric Craniofacial Collaborative Group.” Paediatr Anaesth 32, no. 12 (December 2022): 1339–46. https://doi.org/10.1111/pan.14540.
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    • Derderian, Courtney K., Christopher A. Derderian, Allison Fernandez, Chris D. Glover, Susan Goobie, Jennifer K. Hansen, Michael King, et al. “The Pediatric Craniofacial Collaborative Group (PCCG) Consensus Conference Methodology.” Paediatr Anaesth 31, no. 2 (February 2021): 145–49. https://doi.org/10.1111/pan.14066.
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    • Jalali, Ali, Hannah Lonsdale, Lillian V. Zamora, Luis Ahumada, Anh Thy H. Nguyen, Mohamed Rehman, James Fackler, Paul A. Stricker, Allison M. Fernandez, and Allison M. Pediatric Craniofacial Collaborative Group. “Machine Learning Applied to Registry Data: Development of a Patient-Specific Prediction Model for Blood Transfusion Requirements During Craniofacial Surgery Using the Pediatric Craniofacial Perioperative Registry Dataset.” Anesth Analg 132, no. 1 (January 2021): 160–71. https://doi.org/10.1213/ANE.0000000000004988.
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    • Barnett, Annika M., Kelly A. Machovec, Warwick A. Ames, Hercilia M. Homi, Jennifer L. Turi, Jeannie Koo, Matthew Fuller, and Edmund H. Jooste. “The effect of intraoperative methadone during pediatric cardiac surgery on postoperative opioid requirements.” Paediatr Anaesth 30, no. 7 (July 2020): 773–79. https://doi.org/10.1111/pan.13903.
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    • Fernandez, Patrick G., Brad M. Taicher, Susan M. Goobie, Meera Gangadharan, H Mayumi Homi, Jane A. Kugler, Rochelle Skitt, et al. “Predictors of transfusion outcomes in pediatric complex cranial vault reconstruction: a multicentre observational study from the Pediatric Craniofacial Collaborative Group.” Can J Anaesth 66, no. 5 (May 2019): 512–26. https://doi.org/10.1007/s12630-019-01307-w.
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    • Jooste, Edmund H., Rebecca Scholl, Yi-Hung Wu, Robert D. B. Jaquiss, Andrew J. Lodge, Warwick A. Ames, H Mayumi Homi, et al. “Double-Blind, Randomized, Placebo-Controlled Trial Comparing the Effects of Antithrombin Versus Placebo on the Coagulation System in Infants with Low Antithrombin Undergoing Congenital Cardiac Surgery.” J Cardiothorac Vasc Anesth 33, no. 2 (February 2019): 396–402. https://doi.org/10.1053/j.jvca.2018.05.052.
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    • Tew, Shannon, Manuel L. Fontes, Nathaniel H. Greene, Miklos D. Kertai, George Ofori-Amanfo, Robert D. B. Jaquiss, Andrew J. Lodge, et al. “Natural history of nonimmune-mediated thrombocytopenia and acute kidney injury in pediatric open-heart surgery.” Paediatr Anaesth 27, no. 3 (March 2017): 305–13. https://doi.org/10.1111/pan.13063.
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    • Jooste, Edmund H., Kelly A. Machovec, Lisa M. Einhorn, Warwick A. Ames, Hercilia M. Homi, Robert D. B. Jaquiss, Andrew J. Lodge, Jerrold H. Levy, and Ian J. Welsby. “3-Factor Prothrombin Complex Concentrates in Infants With Refractory Bleeding After Cardiac Surgery.” J Cardiothorac Vasc Anesth 30, no. 6 (December 2016): 1627–31. https://doi.org/10.1053/j.jvca.2016.01.029.
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    • Machovec, Kelly A., Gregory Smigla, Warwick A. Ames, Courtney Schwimer, H Mayumi Homi, Ishwori B. Dhakal, Robert D. B. Jaquiss, Andrew J. Lodge, and Edmund H. Jooste. “Reduction in blood transfusion in a cohort of infants having cardiac surgery with cardiopulmonary bypass after instituting a goal-directed transfusion policy.” Perfusion 31, no. 7 (October 2016): 598–603. https://doi.org/10.1177/0267659116640866.
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    • Machovec, Kelly A., Robert D. B. Jaquiss, David D. Kaemmer, Warwick A. Ames, Hercilia M. Homi, Richard J. Walczak, Andrew J. Lodge, and Edmund H. Jooste. “Cardiopulmonary Bypass Strategy for a Cyanotic Child With Hemoglobin SC Disease.” Ann Thorac Surg 101, no. 6 (June 2016): 2373–75. https://doi.org/10.1016/j.athoracsur.2015.09.046.
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    • Machovec, Kelly A., Edmund H. Jooste, Richard J. Walczak, Hercilia Mayumi Homi, Robert D. B. Jaquiss, Andrew J. Lodge, and Warwick A. Ames. “A change in anticoagulation monitoring improves safety, reduces transfusion, and reduces costs in infants on cardiopulmonary bypass.” Paediatr Anaesth 25, no. 6 (June 2015): 580–86. https://doi.org/10.1111/pan.12591.
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    • Homi, H Mayumi, Wilbert L. Jones, Fellery de Lange, G Burkhard Mackensen, and Hilary P. Grocott. “Exacerbation of systemic inflammation and increased cerebral infarct volume with cardiopulmonary bypass after focal cerebral ischemia in the rat.” J Thorac Cardiovasc Surg 140, no. 3 (September 2010): 660-666.e1. https://doi.org/10.1016/j.jtcvs.2009.10.063.
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    • Homi, H Mayumi, Huaxin Sheng, Gowthami M. Arepally, G Burkhard Mackensen, and Hilary P. Grocott. “Aprotinin improves functional outcome but not cerebral infarct size in an experimental model of stroke during cardiopulmonary bypass.” Anesth Analg 111, no. 1 (July 2010): 38–45. https://doi.org/10.1213/ANE.0b013e3181e0549f.
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    • Homi, H Mayumi, Carla L. Calvi, J. Lynch, and Hilary P. Grocott. “Longitudinal assessment of neurocognitive function in rats after cardiopulmonary bypass: evidence for long-term deficits.” J Cardiothorac Vasc Anesth 24, no. 2 (April 2010): 293–99. https://doi.org/10.1053/j.jvca.2009.07.020.
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    • Yang, Wei, Huaxin Sheng, H Mayumi Homi, David S. Warner, and Wulf Paschen. “Cerebral ischemia/stroke and small ubiquitin-like modifier (SUMO) conjugation--a new target for therapeutic intervention?” J Neurochem 106, no. 3 (August 2008): 989–99. https://doi.org/10.1111/j.1471-4159.2008.05404.x.
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    • Homi, H Mayumi, Christopher Sulzer, George Lappas, Thomas D’Amico, and Mark Stafford-Smith. “Suitability of the lumbar test dose for the thoracic epidural space.” J Cardiothorac Vasc Anesth 20, no. 5 (October 2006): 700–703. https://doi.org/10.1053/j.jvca.2006.01.027.
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    • Clark, Jeffrey A., Daqing Ma, H Mayumi Homi, Mervyn Maze, and Hilary P. Grocott. “Xenon and the inflammatory response to cardiopulmonary bypass in the rat.” J Cardiothorac Vasc Anesth 19, no. 4 (August 2005): 488–93. https://doi.org/10.1053/j.jvca.2005.05.007.
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    • Grocott, Hilary P., H Mayumi Homi, and Ferenc Puskas. “Cognitive dysfunction after cardiac surgery: revisiting etiology.” Semin Cardiothorac Vasc Anesth 9, no. 2 (June 2005): 123–29. https://doi.org/10.1177/108925320500900204.
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    • Grocott, H. P., Y. Sato, H. M. Homi, and B. E. Smith. “The influence of xenon, nitrous oxide and nitrogen on gas bubble expansion during cardiopulmonary bypass.” Eur J Anaesthesiol 22, no. 5 (May 2005): 353–58. https://doi.org/10.1017/s0265021505000608.
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    • Homi, H Mayumi, Hong Yang, Robert D. Pearlstein, and Hilary P. Grocott. “Hemodilution during cardiopulmonary bypass increases cerebral infarct volume after middle cerebral artery occlusion in rats.” Anesth Analg 99, no. 4 (October 2004): 974–81. https://doi.org/10.1213/01.ANE.0000131504.90754.D0.
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    • Yang, Hong, H Mayumi Homi, Betty E. Smith, and Hilary P. Grocott. “Cardiopulmonary bypass reduces the minimum alveolar concentration for isoflurane.” J Cardiothorac Vasc Anesth 18, no. 5 (October 2004): 620–23. https://doi.org/10.1053/j.jvca.2004.07.001.
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    • Grocott, Hilary P., Jeffrey A. Clark, H Mayumi Homi, and Ajeet Sharma. “"Other" neurologic complications after cardiac surgery.” Semin Cardiothorac Vasc Anesth 8, no. 3 (September 2004): 213–26. https://doi.org/10.1177/108925320400800304.
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    • Yokoo, Noriko, Huaxin Sheng, Javier Mixco, H Mayumi Homi, Robert D. Pearlstein, and David S. Warner. “Intraischemic nitrous oxide alters neither neurologic nor histologic outcome: a comparison with dizocilpine.” Anesth Analg 99, no. 3 (September 2004): 896–903. https://doi.org/10.1213/01.ANE.0000132973.32387.8B.
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    • Abraini, Jacques H., Hélène N. David, Olivier Nicole, Eric T. MacKenzie, Alain Buisson, and Marc Lemaire. “Neuroprotection by nitrous oxide and xenon and its relation to minimum alveolar concentration.” Anesthesiology 101, no. 1 (July 2004): 260–61. https://doi.org/10.1097/00000542-200407000-00049.
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    • Sheng, Huaxin, Haichen Wang, Hercilia M. Homi, Ivan Spasojevic, Ines Batinic-Haberle, Robert D. Pearlstein, and David S. Warner. “A no-laminectomy spinal cord compression injury model in mice.” J Neurotrauma 21, no. 5 (May 2004): 595–603. https://doi.org/10.1089/089771504774129928.
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    • Homi, H Mayumi, Javier M. Mixco, Huaxin Sheng, Hilary P. Grocott, Robert D. Pearlstein, and David S. Warner. “Severe hypotension is not essential for isoflurane neuroprotection against forebrain ischemia in mice.” Anesthesiology 99, no. 5 (November 2003): 1145–51. https://doi.org/10.1097/00000542-200311000-00022.
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    • Homi, H Mayumi, Noriko Yokoo, Daqing Ma, David S. Warner, Nicholas P. Franks, Mervyn Maze, and Hilary P. Grocott. “The neuroprotective effect of xenon administration during transient middle cerebral artery occlusion in mice.” Anesthesiology 99, no. 4 (October 2003): 876–81. https://doi.org/10.1097/00000542-200310000-00020.
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    • Homi, Hercília M., Jofre J. S. Freitas, Rui Curi, Irineu T. Velasco, and Bonfim A. S. Junior. “Changes in superoxide dismutase and catalase activities of rat brain regions during early global transient ischemia/reperfusion.” Neurosci Lett 333, no. 1 (November 15, 2002): 37–40. https://doi.org/10.1016/s0304-3940(02)00983-7.
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