Hussein Rashid Al-Khalidi

Hussein Rashid Al-Khalidi
Associate Professor of Biostatistics and Bioinformatics

My research interest includes design and analysis of cardiovascular clinical trials, medical devices, survival analysis, group-sequential analysis, time-to-recurrent or multiple events, continuous-time Markov models, stochastic process, linear model, dose-response modeling, design of experiments and adaptive designs.

Current Appointments & Affiliations

Associate Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2010
Membership in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2010

Contact Information

200 Morris Street (Office #6830), Durham, NC 27701
Duke Box 3850, Durham, NC 27710
hussein.al-khalidi@duke.edu (919) 668-2923

Background
Education, Training, & Certifications
- Ph.D., Texas A&M University 1988
Research
Selected Grants
- Postdoctoral Training in Cardiovascular Clinical Research awarded by National Institutes of Health 2003 - 2024
- Urinary Stone Disease Research Network: Scientific Data Research Center awarded by National Institutes of Health 2016 - 2021
- STICHES awarded by National Institutes of Health 2011 - 2019
- PROMISE Substudy to Assess For Effective dose of Radiation (PROMISE-SAFER) awarded by Columbia University 2011 - 2018
- Heart Rescue Flagship Premier Partner Program "RACE CARs" awarded by Medtronic Foundation 2013 - 2017
- Claret Sentinel System Statistical Analysis awarded by Claret Medical, Inc. 2016 - 2017
- HeartRescue awarded by University of Washington 2016 - 2017
- CABANA-AF Trial awarded by National Institutes of Health 2009 - 2017
- PROMISE Trial: SDCC awarded by National Institutes of Health 2009 - 2015
- ICD Therapy in Patients with Congestive Heart Failure awarded by National Institutes of Health 2009 - 2014
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Nicolau, JC, Stevens, SR, Al-Khalidi, HR, Jatene, FB, Furtado, RHM, Dallan, LAO, Lisboa, LAF, Desvigne-Nickens, P, Haddad, H, Jolicoeur, EM, Petrie, MC, Doenst, T, Michler, RE, Ohman, EM, Maddury, J, Ali, I, Deja, MA, Rouleau, JL, Velazquez, EJ, and Hill, JA. "Does prior coronary angioplasty affect outcomes of surgical coronary revascularization? Insights from the STICH trial." International Journal of Cardiology (March 15, 2019). Full Text
  - Packer, DL, Mark, DB, Robb, RA, Monahan, KH, Bahnson, TD, Poole, JE, Noseworthy, PA, Rosenberg, YD, Jeffries, N, Mitchell, LB, Flaker, GC, Pokushalov, E, Romanov, A, Bunch, TJ, Noelker, G, Ardashev, A, Revishvili, A, Wilber, DJ, Cappato, R, Kuck, K-H, Hindricks, G, Davies, DW, Kowey, PR, Naccarelli, GV, Reiffel, JA, Piccini, JP, Silverstein, AP, Al-Khalidi, HR, Lee, KL, and CABANA Investigators, . "Effect of Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial." Jama (March 15, 2019). Full Text
  - Ambrosy, AP, Stevens, SR, Al-Khalidi, HR, Rouleau, JL, Bouabdallaoui, N, Carson, PE, Adlbrecht, C, Cleland, JGF, Dabrowski, R, Golba, KS, Pina, IL, Sueta, CA, Roy, A, Sopko, G, Bonow, RO, Velazquez, EJ, and STICH Trial Investigators, . "Burden of medical co-morbidities and benefit from surgical revascularization in patients with ischaemic cardiomyopathy." European Journal of Heart Failure 21, no. 3 (March 2019): 373-381. Full Text
  - Sharma, A, Coles, A, Sekaran, NK, Pagidipati, NJ, Lu, MT, Mark, DB, Lee, KL, Al-Khalidi, HR, Hoffmann, U, and Douglas, PS. "Stress Testing Versus CT Angiography in Patients With Diabetes and Suspected Coronary Artery Disease." Journal of the American College of Cardiology 73, no. 8 (March 2019): 893-902. Full Text
  - Cocoros, NM, Pokorney, SD, Haynes, K, Garcia, C, Al-Khalidi, HR, Al-Khatib, SM, Archdeacon, P, Goldsack, JC, Harkins, T, Lin, ND, Martin, D, McCall, D, Nair, V, Parlett, L, Temple, R, McMahill-Walraven, C, Granger, CB, and Platt, R. "FDA-Catalyst-Using FDA's Sentinel Initiative for large-scale pragmatic randomized trials: Approach and lessons learned during the planning phase of the first trial." Clinical Trials (London, England) 16, no. 1 (February 2019): 90-97. Full Text
  - Kochar, A, Al-Khalidi, HR, Doerfler, S, and Granger, CB. "Reply: Delays From First Medical Contact to Revascularization in Patients With ST-Segment Elevation Myocardial Infarction Presenting With Cardiogenic Shock." Jacc. Cardiovascular Interventions 12, no. 1 (January 2019): 107-null. (Letter) Full Text
  - Bouabdallaoui, N, Stevens, SR, Doenst, T, Petrie, MC, Al-Attar, N, Ali, IS, Ambrosy, AP, Barton, AK, Cartier, R, Cherniavsky, A, Demondion, P, Desvigne-Nickens, P, Favaloro, RR, Gradinac, S, Heinisch, P, Jain, A, Jasinski, M, Jouan, J, Kalil, RAK, Menicanti, L, Michler, RE, Rao, V, Smith, PK, Zembala, M, Velazquez, EJ, Al-Khalidi, HR, Rouleau, JL, and STICH Trial Investigators, . "Society of Thoracic Surgeons Risk Score and EuroSCORE-2 Appropriately Assess 30-Day Postoperative Mortality in the STICH Trial and a Contemporary Cohort of Patients With Left Ventricular Dysfunction Undergoing Surgical Revascularization." Circulation. Heart Failure 11, no. 11 (November 2018): e005531-null. Full Text
  - Kochar, A, Al-Khalidi, HR, Hansen, SM, Shavadia, JS, Roettig, ML, Fordyce, CB, Doerfler, S, Gersh, BJ, Henry, TD, Berger, PB, Jollis, JG, and Granger, CB. "Delays in Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction Patients Presenting With Cardiogenic Shock." Jacc. Cardiovascular Interventions 11, no. 18 (September 2018): 1824-1833. Full Text
  - Pellikka, PA, She, L, Holly, TA, Lin, G, Varadarajan, P, Pai, RG, Bonow, RO, Pohost, GM, Panza, JA, Berman, DS, Prior, DL, Asch, FM, Borges-Neto, S, Grayburn, P, Al-Khalidi, HR, Miszalski-Jamka, K, Desvigne-Nickens, P, Lee, KL, Velazquez, EJ, and Oh, JK. "Variability in Ejection Fraction Measured By Echocardiography, Gated Single-Photon Emission Computed Tomography, and Cardiac Magnetic Resonance in Patients With Coronary Artery Disease and Left Ventricular Dysfunction." Jama Network Open 1, no. 4 (August 3, 2018): e181456-null. Full Text
  - Kirchhof, P, Haeusler, KG, Blank, B, De Bono, J, Callans, D, Elvan, A, Fetsch, T, Van Gelder, IC, Gentlesk, P, Grimaldi, M, Hansen, J, Hindricks, G, Al-Khalidi, HR, Massaro, T, Mont, L, Nielsen, JC, Nölker, G, Piccini, JP, De Potter, T, Scherr, D, Schotten, U, Themistoclakis, S, Todd, D, Vijgen, J, and Di Biase, L. "Apixaban in patients at risk of stroke undergoing atrial fibrillation ablation." European Heart Journal 39, no. 32 (August 2018): 2942-2955. Full Text
  - Saito, S, Krucoff, MW, Nakamura, S, Mehran, R, Maehara, A, Al-Khalidi, HR, Rowland, SM, Tasissa, G, Morrell, D, Joseph, D, Okaniwa, Y, Shibata, Y, Bertolet, BD, Rothenberg, MD, Généreux, P, Bezerra, H, and Kong, DF. "Japan-United States of America Harmonized Assessment by Randomized Multicentre Study of OrbusNEich's Combo StEnt (Japan-USA HARMONEE) study: primary results of the pivotal registration study of combined endothelial progenitor cell capture and drug-eluting stent in patients with ischaemic coronary disease and non-ST-elevation acute coronary syndrome." European Heart Journal 39, no. 26 (July 2018): 2460-2468. Full Text
  - Bouabdallaoui, N, Stevens, SR, Doenst, T, Wrobel, K, Bouchard, D, Deja, MA, Michler, RE, Chua, YL, Kalil, RAK, Selzman, CH, Daly, RC, Sun, B, Djokovic, LT, Sopko, G, Velazquez, EJ, Rouleau, JL, Lee, KL, Al-Khalidi, HR, and STICH Trial Investigators, . "Impact of Intubation Time on Survival following Coronary Artery Bypass Grafting: Insights from the Surgical Treatment for Ischemic Heart Failure (STICH) Trial." Journal of Cardiothoracic and Vascular Anesthesia 32, no. 3 (June 2018): 1256-1263. Full Text
  - Packer, DL, Mark, DB, Robb, RA, Monahan, KH, Bahnson, TD, Moretz, K, Poole, JE, Mascette, A, Rosenberg, Y, Jeffries, N, Al-Khalidi, HR, Lee, KL, and CABANA Investigators, . "Catheter Ablation versus Antiarrhythmic Drug Therapy for Atrial Fibrillation (CABANA) Trial: Study Rationale and Design." American Heart Journal 199 (May 2018): 192-199. (Review) Full Text
  - Piccini, JP, Connolly, SJ, Abraham, WT, Healey, JS, Steinberg, BA, Al-Khalidi, HR, Dignacco, P, van Veldhuisen, DJ, Sauer, WH, White, M, Wilton, SB, Anand, IS, Dufton, C, Marshall, DA, Aleong, RG, Davis, GW, Clark, RL, Emery, LL, and Bristow, MR. "A genotype-directed comparative effectiveness trial of Bucindolol and metoprolol succinate for prevention of symptomatic atrial fibrillation/atrial flutter in patients with heart failure: Rationale and design of the GENETIC-AF trial." American Heart Journal 199 (May 2018): 51-58. Full Text
  - Jollis, JG, Al-Khalidi, HR, Roettig, ML, Berger, PB, Corbett, CC, Doerfler, SM, Fordyce, CB, Henry, TD, Hollowell, L, Magdon-Ismail, Z, Kochar, A, McCarthy, JJ, Monk, L, O'Brien, P, Rea, TD, Shavadia, J, Tamis-Holland, J, Wilson, BH, Ziada, KM, and Granger, CB. "Impact of Regionalization of ST-Segment-Elevation Myocardial Infarction Care on Treatment Times and Outcomes for Emergency Medical Services-Transported Patients Presenting to Hospitals With Percutaneous Coronary Intervention: Mission: Lifeline Accelerator-2." Circulation 137, no. 4 (January 2018): 376-387. Full Text
  - Prior, DL, Stevens, SR, Al-Khalidi, HR, Holly, TA, Berman, DS, and STICH Investigators, . "The authors' reply to the letter from Kerkhof et al entitled 'The importance of (measuring) the end-systolic volume index in predicting survival'." Heart (British Cardiac Society) 104, no. 2 (January 2018): 1-null. (Letter) Full Text
  - Stewart, RAH, Szalewska, D, Stebbins, A, Al-Khalidi, HR, Cleland, JGH, Rynkiewicz, A, Drazner, MH, White, HD, Mark, DB, Roy, A, Kosevic, D, Rajda, M, Jasinski, M, Leng, CY, Tungsubutra, W, Desvigne-Nickens, P, Velazquez, EJ, and Petrie, MC. "Six-minute walk distance after coronary artery bypass grafting compared with medical therapy in ischaemic cardiomyopathy." Open Heart 5, no. 1 (January 2018): e000752-null. Full Text Open Access Copy
  - Trattner, S, Halliburton, S, Thompson, CM, Xu, Y, Chelliah, A, Jambawalikar, SR, Peng, B, Peters, MR, Jacobs, JE, Ghesani, M, Jang, JJ, Al-Khalidi, H, and Einstein, AJ. "Cardiac-Specific Conversion Factors to Estimate Radiation Effective Dose From Dose-Length Product in Computed Tomography." Jacc. Cardiovascular Imaging 11, no. 1 (January 2018): 64-74. Full Text
  - Sharma, A, Sekaran, NK, Coles, A, Pagidipati, NJ, Hoffmann, U, Mark, DB, Lee, KL, Al-Khalidi, HR, Lu, MT, Pellikka, PA, Truong, QA, and Douglas, PS. "Impact of Diabetes Mellitus on the Evaluation of Stable Chest Pain Patients: Insights From the PROMISE (Prospective Multicenter Imaging Study for Evaluation of Chest Pain) Trial." Journal of the American Heart Association 6, no. 11 (October 31, 2017). Full Text
  - Hinohara, TT, Al-Khalidi, HR, Fordyce, CB, Gu, X, Sherwood, MW, Roettig, ML, Corbett, CC, Monk, L, Tamis-Holland, JE, Berger, PB, Burchenal, JEB, Wilson, BH, Jollis, JG, and Granger, CB. "Impact of Regional Systems of Care on Disparities in Care Among Female and Black Patients Presenting With ST-Segment-Elevation Myocardial Infarction." Journal of the American Heart Association 6, no. 10 (October 24, 2017). Full Text
  - Kragholm, K, Lu, D, Chiswell, K, Al-Khalidi, HR, Roettig, ML, Roe, M, Jollis, J, and Granger, CB. "Improvement in Care and Outcomes for Emergency Medical Service-Transported Patients With ST-Elevation Myocardial Infarction (STEMI) With and Without Prehospital Cardiac Arrest: A Mission: Lifeline STEMI Accelerator Study." Journal of the American Heart Association 6, no. 10 (October 11, 2017). Full Text
  - Vinereanu, D, Al-Khalidi, HR, Rao, MP, He, W, Lopes, RD, Bahit, CM, Ciobanu, AO, Fox, KA, Pokorney, SD, Xian, Y, Jiang, J, Kamath, DY, Berwanger, O, Tajer, C, Huo, Y, Xavier, D, and Granger, CB. "Regional differences in presentation and antithrombotic treatment of patients with atrial fibrillation: Baseline characteristics from a clustered randomized trial to IMProve treatment with AntiCoagulanTs in patients with atrial fibrillation (IMPACT-AF)." American Heart Journal 192 (October 2017): 38-47. Full Text
  - Vinereanu, D, Lopes, RD, Bahit, MC, Xavier, D, Jiang, J, Al-Khalidi, HR, He, W, Xian, Y, Ciobanu, AO, Kamath, DY, Fox, KA, Rao, MP, Pokorney, SD, Berwanger, O, Tajer, C, de Barros E Silva, PGM, Roettig, ML, Huo, Y, Granger, CB, and IMPACT-AF investigators, . "A multifaceted intervention to improve treatment with oral anticoagulants in atrial fibrillation (IMPACT-AF): an international, cluster-randomised trial." Lancet (London, England) 390, no. 10104 (October 2017): 1737-1746. Full Text
  - Lu, MT, Douglas, PS, Udelson, JE, Adami, E, Ghoshhajra, BB, Picard, MH, Roberts, R, Lee, KL, Einstein, AJ, Mark, DB, Velazquez, EJ, Carter, W, Ridner, M, Al-Khalidi, HR, and Hoffmann, U. "Safety of coronary CT angiography and functional testing for stable chest pain in the PROMISE trial: A randomized comparison of test complications, incidental findings, and radiation dose." Journal of Cardiovascular Computed Tomography 11, no. 5 (September 2017): 373-382. Full Text Open Access Copy
  - Prior, DL, Stevens, SR, Holly, TA, Krejca, M, Paraforos, A, Pohost, GM, Byrd, K, Kukulski, T, Jones, RH, Desvigne-Nickens, P, Varadarajan, P, Amanullah, A, Lin, G, Al-Khalidi, HR, Aldea, G, Santambrogio, C, Bochenek, A, Berman, DS, and STICH Trial Investigators, . "Regional left ventricular function does not predict survival in ischaemic cardiomyopathy after cardiac surgery." Heart (British Cardiac Society) 103, no. 17 (September 2017): 1359-1367. Full Text
  - Hess, PL, Al-Khalidi, HR, Friedman, DJ, Mulder, H, Kucharska-Newton, A, Rosamond, WR, Lopes, RD, Gersh, BJ, Mark, DB, Curtis, LH, Post, WS, Prineas, RJ, Sotoodehnia, N, and Al-Khatib, SM. "The Metabolic Syndrome and Risk of Sudden Cardiac Death: The Atherosclerosis Risk in Communities Study." Journal of the American Heart Association 6, no. 8 (August 23, 2017). Full Text
  - Miszalski-Jamka, K, Jefferies, JL, Mazur, W, Głowacki, J, Hu, J, Lazar, M, Gibbs, RA, Liczko, J, Kłyś, J, Venner, E, Muzny, DM, Rycaj, J, Białkowski, J, Kluczewska, E, Kalarus, Z, Jhangiani, S, Al-Khalidi, H, Kukulski, T, Lupski, JR, Craigen, WJ, and Bainbridge, MN. "Novel Genetic Triggers and Genotype-Phenotype Correlations in Patients With Left Ventricular Noncompaction." Circulation. Cardiovascular Genetics 10, no. 4 (August 2017). Full Text
  - Kong, DF, Saito, S, Nakamura, S, Mehran, R, Rowland, SM, Handler, A, Al-Khalidi, HR, and Krucoff, MW. "Rationale and design of the Japan-USA harmonized assessment by randomized, multicenter study of OrbusNEich's combo StEnt (Japan-USA HARMONEE): Assessment of a novel DES platform for percutaneous coronary revascularization in patients with ischemic coronary disease and non-ST-elevation acute coronary syndrome." American Heart Journal 187 (May 2017): 112-121. Full Text
  - Pai, RG, Varadarajan, P, Rouleau, JL, Stebbins, AL, Velazquez, EJ, Al-Khalidi, HR, and Pohost, GM. "Value of Cardiovascular Magnetic Resonance Imaging-Derived Baseline Left Ventricular Ejection Fraction and Volumes for Precise Risk Stratification of Patients With Ischemic Cardiomyopathy: Insights From the Surgical Treatment for Ischemic Heart Failure (STICH) Trial." JAMA cardiology 2, no. 5 (May 2017): 577-579. Full Text
  - Fordyce, CB, Douglas, PS, Roberts, RS, Hoffmann, U, Al-Khalidi, HR, Patel, MR, Granger, CB, Kostis, J, Mark, DB, Lee, KL, Udelson, JE, and Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) Investigators, . "Identification of Patients With Stable Chest Pain Deriving Minimal Value From Noninvasive Testing: The PROMISE Minimal-Risk Tool, A Secondary Analysis of a Randomized Clinical Trial." Jama Cardiology 2, no. 4 (April 2017): 400-408. Full Text
  - Di Biase, L, Callans, D, Hæusler, KG, Hindricks, G, Al-Khalidi, H, Mont, L, Cosedis Nielsen, J, Piccini, JP, Schotten, U, and Kirchhof, P. "Rationale and design of AXAFA-AFNET 5: an investigator-initiated, randomized, open, blinded outcome assessment, multi-centre trial to comparing continuous apixaban to vitamin K antagonists in patients undergoing atrial fibrillation catheter ablation." Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology 19, no. 1 (January 2017): 132-138. Full Text
  - Fordyce, CB, Al-Khalidi, HR, Jollis, JG, Roettig, ML, Gu, J, Bagai, A, Berger, PB, Corbett, CC, Dauerman, HL, Fox, K, Garvey, JL, Henry, TD, Rokos, IC, Sherwood, MW, Wilson, BH, Granger, CB, and STEMI Systems Accelerator Project, . "Association of Rapid Care Process Implementation on Reperfusion Times Across Multiple ST-Segment-Elevation Myocardial Infarction Networks." Circulation. Cardiovascular Interventions 10, no. 1 (January 2017). Full Text
  - Bedair, K, Hong, Y, Li, J, and Al-Khalidi, HR. "Multivariate frailty models for multi-type recurrent event data and its application to cancer prevention trial." Computational Statistics and Data Analysis 101 (September 1, 2016): 161-173. Full Text
  - Jollis, JG, Al-Khalidi, HR, Roettig, ML, Berger, PB, Corbett, CC, Dauerman, HL, Fordyce, CB, Fox, K, Garvey, JL, Gregory, T, Henry, TD, Rokos, IC, Sherwood, MW, Suter, RE, Wilson, BH, Granger, CB, and Mission: Lifeline STEMI Systems Accelerator Project, . "Regional Systems of Care Demonstration Project: American Heart Association Mission: Lifeline STEMI Systems Accelerator." Circulation 134, no. 5 (August 2016): 365-374. Full Text
  - Povsic, TJ, Henry, TD, Traverse, JH, Fortuin, FD, Schaer, GL, Kereiakes, DJ, Schatz, RA, Zeiher, AM, White, CJ, Stewart, DJ, Jolicoeur, EM, Bass, T, Henderson, DA, Dignacco, P, Gu, Z, Al-Khalidi, HR, Junge, C, Nada, A, Hunt, AS, Losordo, DW, and RENEW Investigators, . "The RENEW Trial: Efficacy and Safety of Intramyocardial Autologous CD34(+) Cell Administration in Patients With Refractory Angina." Jacc. Cardiovascular Interventions 9, no. 15 (August 2016): 1576-1585. Full Text
  - Rao, SV, Zeymer, U, Douglas, PS, Al-Khalidi, H, White, JA, Liu, J, Levy, H, Guetta, V, Gibson, CM, Tanguay, J-F, Vermeersch, P, Roncalli, J, Kasprzak, JD, Henry, TD, Frey, N, Kracoff, O, Traverse, JH, Chew, DP, Lopez-Sendon, J, Heyrman, R, and Krucoff, MW. "Bioabsorbable Intracoronary Matrix for Prevention of Ventricular Remodeling After Myocardial Infarction." Journal of the American College of Cardiology 68, no. 7 (August 2016): 715-723. Full Text
  - Mark, DB, Federspiel, JJ, Cowper, PA, Anstrom, KJ, Hoffmann, U, Patel, MR, Davidson-Ray, L, Daniels, MR, Cooper, LS, Knight, JD, Lee, KL, Douglas, PS, and PROMISE Investigators, . "Economic Outcomes With Anatomical Versus Functional Diagnostic Testing for Coronary Artery Disease." Annals of Internal Medicine 165, no. 2 (July 2016): 94-102. Full Text
  - Mehmood, M, Ambach, SA, Taylor, MD, Jefferies, JL, Raman, SV, Taylor, RJ, Sawani, H, Mathew, J, Mazur, W, Hor, KN, and Al-Khalidi, HR. "Relationship of Right Ventricular Size and Function with Respiratory Status in Duchenne Muscular Dystrophy." Pediatric cardiology 37, no. 5 (June 2016): 878-883. Full Text
  - Mehmood, M, Ambach, SA, Taylor, MD, Jefferies, JL, Raman, SV, Taylor, RJ, Sawnani, H, Mathew, J, Mazur, W, Hor, KN, and Al-Khalidi, HR. "Erratum to: Relationship of Right Ventricular Size and Function with Respiratory Status in Duchenne Muscular Dystrophy." Pediatric cardiology 37, no. 5 (June 2016): 989-. Full Text
  - Rao, MP, Ciobanu, AO, Lopes, RD, Fox, KA, Xian, Y, Pokorney, SD, Al-Khalidi, HR, Jiang, J, Kamath, DY, Berwanger, O, Xavier, D, Bahit, CM, Tajer, C, Vinereanu, D, Huo, Y, and Granger, CB. "A clustered randomized trial to IMProve treatment with AntiCoagulanTs in patients with Atrial Fibrillation (IMPACT-AF): design and rationale." American heart journal 176 (June 2016): 107-113. Full Text
  - Velazquez, EJ, Lee, KL, Jones, RH, Al-Khalidi, HR, Hill, JA, Panza, JA, Michler, RE, Bonow, RO, Doenst, T, Petrie, MC, Oh, JK, She, L, Moore, VL, Desvigne-Nickens, P, Sopko, G, Rouleau, JL, and STICHES Investigators, . "Coronary-Artery Bypass Surgery in Patients with Ischemic Cardiomyopathy." The New England Journal of Medicine 374, no. 16 (April 3, 2016): 1511-1520. Full Text
  - Garber, AM, Mentz, RJ, Al-Khalidi, HR, Shaw, LK, Fiuzat, M, O'Connor, CM, and Velazquez, EJ. "Clinical predictors and outcomes of patients with left ventricular thrombus following ST-segment elevation myocardial infarction." Journal of thrombosis and thrombolysis 41, no. 3 (April 2016): 365-373. Full Text
  - Jolicœur, EM, Dunning, A, Castelvecchio, S, Dabrowski, R, Waclawiw, MA, Petrie, MC, Stewart, R, Jhund, PS, Desvigne-Nickens, P, Panza, JA, Bonow, RO, Sun, B, San, TR, Al-Khalidi, HR, Rouleau, JL, Velazquez, EJ, and Cleland, JGF. "Importance of angina in patients with coronary disease, heart failure, and left ventricular systolic dysfunction: insights from STICH." Journal of the American College of Cardiology 66, no. 19 (November 2015): 2092-2100. Full Text
  - Rao, SV, Zeymer, U, Douglas, PS, Al-Khalidi, H, Liu, J, Gibson, CM, Harrison, RW, Joseph, DS, Heyrman, R, and Krucoff, MW. "A randomized, double-blind, placebo-controlled trial to evaluate the safety and effectiveness of intracoronary application of a novel bioabsorbable cardiac matrix for the prevention of ventricular remodeling after large ST-segment elevation myocardial infarction: Rationale and design of the PRESERVATION I trial." American Heart Journal 170, no. 5 (November 2015): 929-937. Full Text
  - Velazquez, EJ, Samad, Z, Al-Khalidi, HR, Sangli, C, Grayburn, PA, Massaro, JM, Stevens, SR, Feldman, TE, and Krucoff, MW. "The MitraClip and survival in patients with mitral regurgitation at high risk for surgery: A propensity-matched comparison." American Heart Journal 170, no. 5 (November 2015): 1050-1059.e3. Full Text
  - Mehmood, M, Hor, KN, Al-Khalidi, HR, Benson, DW, Jefferies, JL, Taylor, MD, Egnaczyk, GF, Raman, SV, Basu, SK, Cripe, LH, Germann, J, and Mazur, W. "Comparison of right and left ventricular function and size in Duchenne muscular dystrophy." European journal of radiology 84, no. 10 (October 2015): 1938-1942. Full Text
  - Samad, Z, Shaw, LK, Phelan, M, Ersboll, M, Risum, N, Al-Khalidi, HR, Glower, DD, Milano, CA, Alexander, JH, O'Connor, CM, Wang, A, and Velazquez, EJ. "Management and outcomes in patients with moderate or severe functional mitral regurgitation and severe left ventricular dysfunction." European Heart Journal 36, no. 40 (October 2015): 2733-2741. Full Text
  - Wrobel, K, Stevens, SR, Jones, RH, Selzman, CH, Lamy, A, Beaver, TM, Djokovic, LT, Wang, N, Velazquez, EJ, Sopko, G, Kron, IL, DiMaio, JM, Michler, RE, Lee, KL, Yii, M, Leng, CY, Zembala, M, Rouleau, JL, Daly, RC, and Al-Khalidi, HR. "Influence of Baseline Characteristics, Operative Conduct, and Postoperative Course on 30-Day Outcomes of Coronary Artery Bypass Grafting Among Patients With Left Ventricular Dysfunction: Results From the Surgical Treatment for Ischemic Heart Failure (STICH) Trial." Circulation 132, no. 8 (August 2015): 720-730. Full Text
  - Held, C, Hylek, EM, Alexander, JH, Hanna, M, Lopes, RD, Wojdyla, DM, Thomas, L, Al-Khalidi, H, Alings, M, Xavier, D, Ansell, J, Goto, S, Ruzyllo, W, Rosenqvist, M, Verheugt, FWA, Zhu, J, Granger, CB, and Wallentin, L. "Clinical outcomes and management associated with major bleeding in patients with atrial fibrillation treated with apixaban or warfarin: insights from the ARISTOTLE trial." European Heart Journal 36, no. 20 (May 2015): 1264-1272. Full Text
  - Pun, PH, Hellkamp, AS, Sanders, GD, Middleton, JP, Hammill, SC, Al-Khalidi, HR, Curtis, LH, Fonarow, GC, and Al-Khatib, SM. "Primary prevention implantable cardioverter defibrillators in end-stage kidney disease patients on dialysis: a matched cohort study." Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 30, no. 5 (May 2015): 829-835. Full Text
  - Póvoa, P, Salluh, JIF, Martinez, ML, Guillamat-Prats, R, Gallup, D, Al-Khalidi, HR, Thompson, BT, Ranieri, VM, and Artigas, A. "Clinical impact of stress dose steroids in patients with septic shock: insights from the PROWESS-Shock trial." Critical Care (London, England) 19 (April 28, 2015): 193-null. Full Text
  - Douglas, PS, Hoffmann, U, Patel, MR, Mark, DB, Al-Khalidi, HR, Cavanaugh, B, Cole, J, Dolor, RJ, Fordyce, CB, Huang, M, Khan, MA, Kosinski, AS, Krucoff, MW, Malhotra, V, Picard, MH, Udelson, JE, Velazquez, EJ, Yow, E, Cooper, LS, Lee, KL, and PROMISE Investigators, . "Outcomes of anatomical versus functional testing for coronary artery disease." The New England Journal of Medicine 372, no. 14 (April 2015): 1291-1300. Full Text
  - Pokorney, SD, Hellkamp, AS, Yancy, CW, Curtis, LH, Hammill, SC, Peterson, ED, Masoudi, FA, Bhatt, DL, Al-Khalidi, HR, Heidenreich, PA, Anstrom, KJ, Fonarow, GC, and Al-Khatib, SM. "Primary prevention implantable cardioverter-defibrillators in older racial and ethnic minority patients." Circulation. Arrhythmia and Electrophysiology 8, no. 1 (February 2015): 145-151. Full Text
  - Zeitler, EP, Hellkamp, AS, Fonarow, GC, Hammill, SC, Curtis, LH, Hernandez, AF, Al-Khalidi, HR, Curtis, JP, Heidenreich, PA, Anstrom, KJ, Peterson, ED, Mark, DB, Hammill, BG, Sanders, GD, and Al-Khatib, SM. "Primary prevention implantable cardioverter-defibrillators and survival in older women." Jacc. Heart Failure 3, no. 2 (February 2015): 159-167. Full Text
  - Hor, KN, Kissoon, N, Mazur, W, Gupta, R, Ittenbach, RF, Al-Khalidi, HR, Cripe, LH, Raman, SV, Puchalski, MD, Gottliebson, WM, and Benson, DW. "Regional circumferential strain is a biomarker for disease severity in duchenne muscular dystrophy heart disease: a cross-sectional study." Pediatric cardiology 36, no. 1 (January 2015): 111-119. Full Text
  - Miszalski-Jamka, T, Szczeklik, W, Sokołowska, B, Karwat, K, Miszalski-Jamka, K, Jaźwiec, P, Małek, ŁA, Al-Khalidi, H, Schulz-Menger, J, Mavrogeni, S, Mahr, A, Mazur, W, Kereiakes, DJ, and Musiał, J. "Noncorticosteroid immunosuppression limits myocardial damage and contractile dysfunction in eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)." Journal of the American College of Cardiology 65, no. 1 (January 2015): 103-105. (Letter) Full Text
  - Póvoa, P, Salluh, JI, Martinez, ML, Guillamat-Prats, R, Gallup, D, Al-Khalidi, HR, Thompson, BT, Ranieri, VM, and Artigas, A. "Clinical impact of stress dose steroids in patients with septic shock: Insights from the PROWESS-Shock trial." Critical Care (2015). Full Text
  - Hess, PL, Hellkamp, AS, Peterson, ED, Sanders, GD, Al-Khalidi, HR, Curtis, LH, Hammill, BG, Pun, PH, Curtis, JP, Anstrom, KJ, Hammill, SC, and Al-Khatib, SM. "Survival after primary prevention implantable cardioverter-defibrillator placement among patients with chronic kidney disease." Circulation. Arrhythmia and Electrophysiology 7, no. 5 (October 2014): 793-799. Full Text
  - Newby, LK, Marber, MS, Melloni, C, Sarov-Blat, L, Aberle, LH, Aylward, PE, Cai, G, de Winter, RJ, Hamm, CW, Heitner, JF, Kim, R, Lerman, A, Patel, MR, Tanguay, J-F, Lepore, JJ, Al-Khalidi, HR, Sprecher, DL, Granger, CB, and SOLSTICE Investigators, . "Losmapimod, a novel p38 mitogen-activated protein kinase inhibitor, in non-ST-segment elevation myocardial infarction: a randomised phase 2 trial." Lancet (London, England) 384, no. 9949 (September 2014): 1187-1195. Full Text
  - Hor, KN, Kissoon, N, Mazur, W, Gupta, R, Ittenbach, RF, Al-Khalidi, HR, Cripe, LH, Raman, SV, Puchalski, MD, Gottliebson, WM, and Benson, DW. "Regional circumferential strain is a biomarker for disease severity in duchenne muscular dystrophy heart disease: A cross-sectional study." Pediatric Cardiology 36, no. 1 (August 2, 2014): 111-119. Full Text
  - Al-Khatib, SM, Hellkamp, AS, Fonarow, GC, Mark, DB, Curtis, LH, Hernandez, AF, Anstrom, KJ, Peterson, ED, Sanders, GD, Al-Khalidi, HR, Hammill, BG, Heidenreich, PA, and Hammill, SC. "Association between prophylactic implantable cardioverter-defibrillators and survival in patients with left ventricular ejection fraction between 30% and 35%." Jama 311, no. 21 (June 2014): 2209-2215. Full Text
  - Douglas, PS, Hoffmann, U, Lee, KL, Mark, DB, Al-Khalidi, HR, Anstrom, K, Dolor, RJ, Kosinski, A, Krucoff, MW, Mudrick, DW, Patel, MR, Picard, MH, Udelson, JE, Velazquez, EJ, Cooper, L, and PROMISE investigators, . "PROspective Multicenter Imaging Study for Evaluation of chest pain: rationale and design of the PROMISE trial." American Heart Journal 167, no. 6 (June 2014): 796-803.e1. Full Text
  - "Regional systems of care demonstration project: Mission: Lifeline STEMI Systems Accelerator: Design and methodology." American Heart Journal 167, no. 1 (January 1, 2014). Full Text
  - Bagai, A, Al-Khalidi, HR, Sherwood, MW, Muñoz, D, Roettig, ML, Jollis, JG, and Granger, CB. "Regional systems of care demonstration project: Mission: Lifeline STEMI Systems Accelerator: design and methodology." American Heart Journal 167, no. 1 (January 2014): 15-21.e3. Full Text
  - Douglas, PS, Hoffmann, U, Lee, KL, Mark, DB, Al-Khalidi, HR, Anstrom, K, Dolor, RJ, Kosinski, A, Krucoff, MW, Mudrick, DW, Patel, MR, Picard, MH, Udelson, JE, Velazquez, EJ, and Cooper, L. "PROspective Multicenter Imaging Study for Evaluation of chest pain: Rationale and design of the PROMISE trial." American Heart Journal 167, no. 6 (January 1, 2014). Full Text
  - Newby, LK, Marber, MS, Melloni, C, Sarov-Blat, L, Aberle, LH, Aylward, PE, Cai, G, De Winter, RJ, Hamm, CW, Heitner, JF, Kim, R, Lerman, A, Patel, MR, Tanguay, JF, Lepore, JJ, Al-Khalidi, HR, Sprecher, DL, and Granger, CBI. "Losmapimod, a novel p38 mitogen-activated protein kinase inhibitor, in non-ST-segment elevation myocardial infarction: A randomised phase 2 trial." The Lancet 384, no. 9949 (January 1, 2014): 1187-1195. Full Text
  - Hor, KN, Taylor, MD, Al-Khalidi, HR, Cripe, LH, Raman, SV, Jefferies, JL, O'Donnell, R, Benson, DW, and Mazur, W. "Prevalence and distribution of late gadolinium enhancement in a large population of patients with Duchenne muscular dystrophy: effect of age and left ventricular systolic function." Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance 15 (December 21, 2013): 107-null. Full Text
  - Michler, RE, Rouleau, JL, Al-Khalidi, HR, Bonow, RO, Pellikka, PA, Pohost, GM, Holly, TA, Oh, JK, Dagenais, F, Milano, C, Wrobel, K, Pirk, J, Ali, IS, Jones, RH, Velazquez, EJ, Lee, KL, Di Donato, M, and STICH Trial Investigators, . "Insights from the STICH trial: change in left ventricular size after coronary artery bypass grafting with and without surgical ventricular reconstruction." The Journal of Thoracic and Cardiovascular Surgery 146, no. 5 (November 2013): 1139-1145.e6. Full Text
  - Bagai, A, Al-Khalidi, HR, Muñoz, D, Monk, L, Roettig, ML, Corbett, CC, Garvey, JL, Wilson, BH, Granger, CB, and Jollis, JG. "Bypassing the emergency department and time to reperfusion in patients with prehospital ST-segment-elevation: findings from the reperfusion in acute myocardial infarction in Carolina Emergency Departments project." Circ Cardiovasc Interv 6, no. 4 (August 2013): 399-406. Full Text Link to Item
  - Al-Khatib, SM, Hellkamp, A, Bardy, GH, Hammill, S, Hall, WJ, Mark, DB, Anstrom, KJ, Curtis, J, Al-Khalidi, H, Curtis, LH, Heidenreich, P, Peterson, ED, Sanders, G, Clapp-Channing, N, Lee, KL, and Moss, AJ. "Survival of patients receiving a primary prevention implantable cardioverter-defibrillator in clinical practice vs clinical trials." Jama 309, no. 1 (January 2013): 55-62. Full Text
  - Michler, RE, Rouleau, JL, Al-Khalidi, HR, Bonow, RO, Pellikka, PA, Pohost, GM, Holly, TA, Oh, JK, Dagenais, F, Milano, C, and al, E. "Insights from the STICH trial: Change in left ventricular size after coronary artery bypass grafting with and without surgical ventricular reconstruction." Journal of Thoracic and Cardiovascular Surgery 146, no. 5 (2013): 1139-1145.e6. Full Text
  - Muñoz, D, Roettig, ML, Monk, L, Al-Khalidi, H, Jollis, JG, and Granger, CB. "Transport time and care processes for patients transferred with ST-segment-elevation myocardial infarction: the reperfusion in acute myocardial infarction in Carolina emergency rooms experience." Circulation. Cardiovascular Interventions 5, no. 4 (August 7, 2012): 555-562. Full Text
  - Jollis, JG, Al-Khalidi, HR, Monk, L, Roettig, ML, Garvey, JL, Aluko, AO, Wilson, BH, Applegate, RJ, Mears, G, Corbett, CC, Granger, CB, and Regional Approach to Cardiovascular Emergencies (RACE) Investigators, . "Expansion of a regional ST-segment-elevation myocardial infarction system to an entire state." Circulation 126, no. 2 (July 10, 2012): 189-195. Full Text Link to Item
  - Truffa, AAM, Granger, CB, White, KR, Newby, LK, Mehta, RH, Hochman, JS, Patel, MR, Pieper, KS, Al-Khalidi, HR, Armstrong, PW, and Lopes, RD. "Serious infection after acute myocardial infarction: incidence, clinical features, and outcomes." JACC Cardiovasc Interv 5, no. 7 (July 2012): 769-776. Full Text Link to Item
  - Ranieri, VM, Thompson, BT, Barie, PS, Dhainaut, J-F, Douglas, IS, Finfer, S, Gårdlund, B, Marshall, JC, Rhodes, A, Artigas, A, Payen, D, Tenhunen, J, Al-Khalidi, HR, Thompson, V, Janes, J, Macias, WL, Vangerow, B, Williams, MD, and PROWESS-SHOCK Study Group, . "Drotrecogin alfa (activated) in adults with septic shock." The New England Journal of Medicine 366, no. 22 (May 22, 2012): 2055-2064. Full Text
  - Al-Khatib, SM, Hellkamp, AS, Hernandez, AF, Fonarow, GC, Thomas, KL, Al-Khalidi, HR, Heidenreich, PA, Hammill, S, Yancy, C, Peterson, ED, and Get With the Guidelines Steering Committee and Hospitals, . "Trends in use of implantable cardioverter-defibrillator therapy among patients hospitalized for heart failure: have the previously observed sex and racial disparities changed over time?." Circulation 125, no. 9 (March 2012): 1094-1101. Full Text
  - Mazur, W, Hor, KN, Germann, JT, Fleck, RJ, Al-Khalidi, HR, Wansapura, JP, Chung, ES, Taylor, MD, Jefferies, JL, Benson, DW, and Gottliebson, WM. "Patterns of left ventricular remodeling in patients with Duchenne Muscular Dystrophy: a cardiac MRI study of ventricular geometry, global function, and strain." Int J Cardiovasc Imaging 28, no. 1 (January 2012): 99-107. Full Text Link to Item
  - Al-Khalidi, HR, Hong, Y, Fleming, TR, and Therneau, TM. "Insights on the robust variance estimator under recurrent-events model." Biometrics 67, no. 4 (December 2011): 1564-1572. Full Text Link to Item
  - Samad, Z, Yow, E, Shaw, LK, Al-Khalidi, HR, Arges, K, Toptine, JH, Krucoff, M, Wang, A, Jollis, JG, and Velazquez, EJ. "Prevalence and Natural History of Moderate or Severe Mitral Regurgitation: an Observational Study from a Single Center." CIRCULATION 124, no. 21 (November 22, 2011). Link to Item
  - Hor, KN, Mazur, W, Taylor, MD, Al-Khalidi, HR, Cripe, LH, Jefferies, JL, Raman, SV, Chung, ES, Kinnett, KJ, Williams, K, Gottliebson, WM, and Benson, DW. "Effects of steroids and angiotensin converting enzyme inhibition on circumferential strain in boys with Duchenne muscular dystrophy: a cross-sectional and longitudinal study utilizing cardiovascular magnetic resonance." Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance 13 (October 19, 2011): 60-null. Full Text
  - Granger, CB, Alexander, JH, McMurray, JJV, Lopes, RD, Hylek, EM, Hanna, M, Al-Khalidi, HR, Ansell, J, Atar, D, Avezum, A, Bahit, MC, Diaz, R, Easton, JD, Ezekowitz, JA, Flaker, G, Garcia, D, Geraldes, M, Gersh, BJ, Golitsyn, S, Goto, S, Hermosillo, AG, Hohnloser, SH, Horowitz, J, Mohan, P, Jansky, P, Lewis, BS, Lopez-Sendon, JL, Pais, P, Parkhomenko, A, Verheugt, FWA, Zhu, J, Wallentin, L, and ARISTOTLE Committees and Investigators, . "Apixaban versus warfarin in patients with atrial fibrillation." The New England Journal of Medicine 365, no. 11 (September 2011): 981-992. Full Text
  - Bhatti, S, Hakeem, A, Yousuf, MA, Al-Khalidi, HR, Mazur, W, and Shizukuda, Y. "Diagnostic performance of computed tomography angiography for differentiating ischemic vs nonischemic cardiomyopathy." J Nucl Cardiol 18, no. 3 (May 2011): 407-420. Full Text Link to Item
  - Hor, KN, Wansapura, JP, Al-Khalidi, HR, Gottliebson, WM, Taylor, MD, Czosek, RJ, Nagueh, SF, Akula, N, Chung, ES, Benson, WD, and Mazur, W. "Presence of mechanical dyssynchrony in Duchenne muscular dystrophy." Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance 13 (January 2011): 12-null. Full Text
  - Hor, KN, Gottliebson, WM, Carson, C, Wash, E, Cnota, J, Fleck, R, Wansapura, J, Klimeczek, P, Al-Khalidi, HR, Chung, ES, Benson, DW, and Mazur, W. "Comparison of magnetic resonance feature tracking for strain calculation with harmonic phase imaging analysis." Jacc. Cardiovascular Imaging 3, no. 2 (February 2010): 144-151. Full Text
  - Jolicoeur, EM, O'Neill, WW, Hellkamp, A, Hamm, CW, Holmes, DR, Al-Khalidi, HR, Patel, MR, Van de Werf, FJ, Pieper, K, Armstrong, PW, Granger, CB, and APEX-AMI Investigators, . "Transfusion and mortality in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention." Eur Heart J 30, no. 21 (November 2009): 2575-2583. Full Text Link to Item
  - Dorian, P, Al-Khalidi, HR, Hohnloser, SH, Brum, JM, Dunnmon, PM, Pratt, CM, Holroyde, MJ, Kowey, P, and Shock Inhibition Evaluation with Azimilide Investigators, . "Azimilide reduces emergency department visits and hospitalizations in patients with an implantable cardioverter-defibrillator in a placebo-controlled clinical trial." J Am Coll Cardiol 52, no. 13 (September 23, 2008): 1076-1083. Full Text Link to Item
  - "Zoledronate, fractures, and mortality after hip fracture [4]." New England Journal of Medicine 358, no. 9 (February 28, 2008): 968-969. (Letter)
  - Karam, R, Al-Khalidi, H, and Steinbuch, M. "Zoledronate, fractures, and mortality after hip fracture [3]." New England Journal of Medicine 358, no. 9 (February 28, 2008): 968-null. (Letter)
  - Karam, R, Al-Khalidi, H, and Steinbuch, M. "Zoledronate, fractures, and mortality after hip fracture." The New England Journal of Medicine 358, no. 9 (February 2008): 969-null. (Letter) Full Text
  - Tjandrawidjaja, MC, Fu, Y, Al-Khalidi, H, Todaro, TG, Adams, P, Werf, FVD, Granger, CB, and Armstrong, PW. "Failure of investigator adherence to electrocardiographic entry criteria is frequent and influences clinical outcomes: Lessons from APEX-AMI." European Heart Journal 28, no. 23 (2007): 2850-2857. Full Text
  - Hohnloser, SH, Al-Khalidi, HR, Pratt, CM, Brum, JM, Tatla, DS, Tchou, P, Dorian, P, and SHock Inhibition Evaluation with AzimiLiDe (SHIELD) Investigators, . "Electrical storm in patients with an implantable defibrillator: incidence, features, and preventive therapy: insights from a randomized trial." European Heart Journal 27, no. 24 (December 2006): 3027-3032. Full Text
  - Pratt, CM, Al-Khalidi, HR, Brum, JM, Holroyde, MJ, Schwartz, PJ, Marcello, SR, Borggrefe, M, Dorian, P, Camm, AJ, and Azimilide Trials Investigators, . "Cumulative experience of azimilide-associated torsades de pointes ventricular tachycardia in the 19 clinical studies comprising the azimilide database." Journal of the American College of Cardiology 48, no. 3 (August 2006): 471-477. Full Text
  - Armstrong, PW, Adams, PX, Al-Khalidi, HR, Hamm, C, Holmes, D, O'Neill, W, Todaro, TG, Vahanian, A, Van de Werf, F, Granger, CB, and APEX-AMI Steering Committee, . "Assessment of Pexelizumab in Acute Myocardial Infarction (APEX AMI): a multicenter, randomized, double-blind, parallel-group, placebo-controlled study of pexelizumab in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention." Am Heart J 149, no. 3 (March 2005): 402-407. Full Text Link to Item
  - Pratt, CM, Dorian, P, Al-Khalidi, HR, Brum, JM, Borggrefe, M, Tatla, DS, Brachmann, J, Myerburg, RJ, Cannom, DS, Holroyde, MJ, van der Laan, M, Hohnloser, SH, and SHIELD Investigators, . "Design of the SHock Inhibition Evaluation with Azimilide (SHIELD) study: a novel method to assess antiarrhythmic drug effect in patients with an implantable cardioverter-defibrillator." Am J Cardiol 95, no. 2 (January 15, 2005): 274-276. Full Text Link to Item
  - Dorian, P, Borggrefe, M, Al-Khalidi, HR, Hohnloser, SH, Brum, JM, Tatla, DS, Brachmann, J, Myerburg, RJ, Cannom, DS, van der Laan, M, Holroyde, MJ, Singer, I, Pratt, CM, and SHock Inhibition Evaluation with azimiLiDe (SHIELD) Investigators, . "Placebo-controlled, randomized clinical trial of azimilide for prevention of ventricular tachyarrhythmias in patients with an implantable cardioverter defibrillator." Circulation 110, no. 24 (December 2004): 3646-3654. Full Text
  - Pratt, CM, Singh, SN, Al-Khalidi, HR, Brum, JM, Holroyde, MJ, Marcello, SR, Schwartz, PJ, Camm, AJ, and ALIVE Investigators, . "The efficacy of azimilide in the treatment of atrial fibrillation in the presence of left ventricular systolic dysfunction: results from the Azimilide Postinfarct Survival Evaluation (ALIVE) trial." J Am Coll Cardiol 43, no. 7 (April 7, 2004): 1211-1216. Full Text Link to Item
  - Camm, AJ, Pratt, CM, Schwartz, PJ, Al-Khalidi, HR, Spyt, MJ, Holroyde, MJ, Karam, R, Sonnenblick, EH, Brum, JMG, and AzimiLide post Infarct surVival Evaluation (ALIVE) Investigators, . "Mortality in patients after a recent myocardial infarction: a randomized, placebo-controlled trial of azimilide using heart rate variability for risk stratification." Circulation 109, no. 8 (March 2, 2004): 990-996. Full Text Link to Item
  - Singer, I, Al-Khalidi, H, Niazi, I, Tchou, P, Simmons, T, Henthorn, R, Holroyde, M, and Brum, J. "Azimilide Decreases Recurrent Ventricular Tachyarrhythmias in Patients with Implantable Cardioverter Defibrillators." Journal of the American College of Cardiology 43, no. 1 (2004): 39-43. Full Text
  - Al-Khalidi, HR, Brum, JM, Karam, R, Camm, AJ, Sonnenblick, E, Schwartz, PJ, Ruzyllo, W, Holroyde, MJ, and Pratt, CM. "The ALIVE study: heart rate variability prospectively identifies patients at high risk of death after myocardial infarction." EUROPEAN HEART JOURNAL 22 (September 2001): 696-+. Link to Item
  - Al-Khalidi, HR, Camm, AJ, Brum, JM, Ruda, M, Schwartz, PJ, Spyt, MJ, Pratt, CM, and Holroyde, MJ. "Low heart rate variability (triangular index method) predicts mortality independent of beta-blocker usage, LVEF, and other factors: ALIVE trial early findings." EUROPEAN HEART JOURNAL 22 (September 2001): 701-701. Link to Item
  - Al-Khalidi, HR, Pratt, CM, Brum, JM, Camm, AJ, Schwartz, PJ, Holroyde, MJ, Hislop, CM, and Elkayam, U. "Baseline characteristics that identify patients at high risk of death following myocardial infarction. Preliminary findings from the ALIVE trial." EUROPEAN HEART JOURNAL 22 (September 2001): 700-700. Link to Item
  - Brooks, RR, Drexler, AP, Maynard, AE, Al-Khalidi, H, and Kostreva, DR. "Proarrhythmia of azimilide and other class III antiarrhythmic agents in the adrenergically stimulated rabbit." Proceedings of the Society for Experimental Biology and Medicine 223, no. 2 (2000): 183-189.
  - Corey, A, Al-Khalidi, H, Brezovic, C, Marcello, S, Parekh, N, Taylor, K, and Karam, R. "Azimilide pharmacokinetics and pharmacodynamics upon multiple oral dosing." Biopharmaceutics & drug disposition 20, no. 2 (March 1999): 59-68. Full Text
  - Corey, A, Al-Khalidi, H, Brezovic, C, Marcello, S, Parekh, N, Taylor, K, and Karam, R. "Azimilide pharmacokinetics and pharmacodynamics upon multiple oral dosing." Biopharmaceutics & Drug Disposition 20, no. 2 (March 1999): 59-68. Full Text
  - Corey, A, Al-Khalidi, H, Brezovic, C, Marcello, S, Parekh, N, Taylor, K, and Karam, R. "Azimilide pharmacokinetics and pharmacodynamics upon multiple oral dosing." Clinical Pharmacology and Therapeutics 61, no. 2 (December 1, 1997): 205-null.
  - Al-Khalidi, HR, and Schnell, DJ. "Application of a continuous-time Markov chain to a preclinical study." Drug Information Journal 31, no. 2 (1997): 607-613.
  - Shen, LZ, and Al-Khalidi, HR. "Application of boundary calculation methodologies to group sequential testing in general parametric models." Communications in Statistics Theory and Methods 26, no. 9 (January 1, 1997): 2173-2190. Full Text
  - al-Khalidi, HR, and Schnell, DJ. "Application of a continuous-time markov chain to a preclinical study." Therapeutic Innovation &Amp; Regulatory Science 31, no. 2 (January 1, 1997): 607-613. Full Text
  - Drexler, AP, Ai-Khalidi, H, Maynard, AE, Johnson, NC, Joroensen, RL, Brooks, RR, and Kostreva, PR. "Comparison of azimilide dihydrochloride (NE-10064) and selected class III antiarrhythmic agents in a rabbit model of proarrhythmia." Faseb Journal 10, no. 3 (December 1, 1996).
  - Brint, SU, Al-Khalidi, HR, Vatel, B, and Hier, DB. "MCA flow asymmetry is a marker for cerebrovascular disease." Neurol Res 18, no. 2 (April 1996): 163-167. Link to Item
  - Al-Khalidi, HR. "On the misspecification of a lognormal distribution." Communications in Statistics Theory and Methods 23, no. 8 (January 1, 1994): 2351-2365. Full Text
  - Al-Khalidi, HR, and Parsa, AR. "Some Aspects of Maximum Likelihood Estimation of Multistage Cancer Dose-Response Models with Application." Communications in Statistics Theory and Methods 22, no. 12 (January 1, 1993): 3377-3392. Full Text
  - Holiday, DB, and McLarty, JW. "Comparing time trends in a two-arm longitudinal study with an ordinal categorical response." Communications in Statistics Theory and Methods 22, no. 12 (January 1, 1993): 3569-3590. Full Text
  - Al-Khalidi, HR, and Hwang, LJ. "Some pitfalls of tests of separate families of hypotheses: Normality vs. lognormality." Communications in Statistics Theory and Methods 20, no. 8 (January 1, 1991): 2505-2528. Full Text
- Conference Papers
  - Jollis, JG, Al-Khalidi, HR, Roettig, ML, Monk, L, Berger, PB, Corbett, C, Doerfler, S, Fordyce, C, Henry, TD, Kochar, A, O'Brien, P, Shavadia, J, Wilson, BH, and Granger, CB. "Regional STEMI Systems of Care: Results of the Mission: Lifeline STEMI ACCELERATOR-2 Study." December 12, 2017. Link to Item
  - Vinereanu, D, Al-Khalidi, HR, Rao, MP, Lopes, RL, Bahit, CM, Ciobanu, AO, Pokorney, SD, Xian, Y, Jiang, J, Kamath, DY, Berwanger, O, Tajer, C, Huo, Y, Xavier, D, and Granger, CB. "Determinants of antithrombotic treatment of patients with AF: baseline characteristics from a clustered randomized trial to IMProve treatment with AntiCoagulanTs in patients with AF (IMPACT-AF)." : OXFORD UNIV PRESS, August 1, 2017. Link to Item
  - Lee, KL, Roberts, RS, Mark, DB, Al-Khalidi, HR, Boineau, R, Rosenberg, Y, Stylianou, M, and Lamas, GA. "Behind the Looking Glass: Comparing Time to First Event versus Multiple Events Analyses in a Post-myocardial Infarction Clinical Trial." November 10, 2015. Link to Item
  - Lu, MT, Douglas, PS, Udelson, JE, Adami, EC, Ghoshhajra, BB, Picard, MH, Roberts, R, Lee, KL, Einstein, AJ, Mark, DB, Velazquez, EJ, Carter, W, Ridner, M, Al-Khalidi, HR, and Hoffmann, U. "Safety of Anatomic versus Functional Diagnostic Testing: Insights From the PROMISE Trial (PROspective Multicenter Imaging Study for Evaluation of Chest Pain)." November 10, 2015. Link to Item
  - Sherwood, MW, Al-Khalidi, HR, Jollis, JG, Roettig, ML, Berger, PB, Corbett, CC, Dauerman, HL, Fox, K, Garvey, JL, Henry, TD, Rokos, IC, Wilson, BH, and Granger, CB. "Developing Regional STEMI Systems of Care: Final Results of the Mission: Lifeline STEMI ACCELERATOR Study." Scientific Sessions of the American-Heart-Association and American-Stroke-Association / Resuscitation Science Symposium. Chicago, IL. November 15, 2014 - November 19, 2014. LIPPINCOTT WILLIAMS & WILKINS, December 2, 2014. Link to Item
  - Garber, AM, Mentz, RJ, Shaw, LK, Al-Khalidi, HR, Fiuzat, M, O'Connors, C, and Velazquez, EJ. "Predictors of Left Ventricular Thrombus Following ST-Segment Elevation Myocardial Infarction: Findings From the Duke Databank of Cardiovascular Disease and the Duke Echocardiography Databank." November 26, 2013. Link to Item
  - Granger, CB, Monk, LM, Roettig, ML, Al-Khalidi, HR, Applegate, RJ, Corbett, CC, Garvey, JL, Hathawy, WR, Wilson, BH, and Jollis, JG. "State-Wide Care is Improved in the Reperfusion of Acute MI in Carolina Emergency Department Emergency Response (RACE-ER) Systems Improvement Program." November 23, 2010. Link to Item
  - Dorian, P, Al-khalidi, HR, Hohnloser, SH, Brum, JM, Tatla, DS, van der Laan, M, and Pratt, CM. "Analysis of all recurrent events is superior to the time-to-first event in assessment of drug therapy to prevent ICD therapies." September 2005. Link to Item
  - Dorian, P, Hohnloser, S, Al-Khalidi, HR, Brum, JM, Borggrefe, M, Tatla, DS, Brachmann, J, Myerburg, R, Cannom, D, Vanderlaan, M, Holroyde, MJ, Pratt, CM, and Investigators, SHIELD. "SHock Inhibition Evaluation with AzimiLiDe (SHIELD): A randomized placebo controlled trial of azimilide in reducing ICD therapies." April 5, 2005. Link to Item
Teaching & Mentoring
Recent Courses
- BIOSTAT 705: Applied Biostatistical Methods II 2019

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Recent Courses