Hussein Rashid Al-Khalidi

Hussein Rashid Al-Khalidi
Associate Professor of Biostatistics and Bioinformatics

My research interest includes design and analysis of cardiovascular clinical trials, medical devices, survival analysis, group-sequential analysis, time-to-recurrent or multiple events, continuous-time Markov models, stochastic process, linear model, dose-response modeling, design of experiments and adaptive designs.

Current Appointments & Affiliations

Associate Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2010
Membership in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2010

Contact Information

7001 North Pavilion, 2400 Pratt Street, Durham, NC 27705
Duke Box 3850, Durham, NC 27710
hussein.al-khalidi@duke.edu (919) 668-2923

Background
Education, Training, & Certifications
- Ph.D., Texas A&M University 1988
Research
Selected Grants
- Postdoctoral Training in Cardiovascular Clinical Research awarded by National Institutes of Health 2003 - 2024
- Urinary Stone Disease Research Network: Scientific Data Research Center awarded by National Institutes of Health 2016 - 2021
- STICHES awarded by National Institutes of Health 2011 - 2019
- PROMISE Substudy to Assess For Effective dose of Radiation (PROMISE-SAFER) awarded by Columbia University 2011 - 2018
- Heart Rescue Flagship Premier Partner Program "RACE CARs" awarded by Medtronic Foundation 2013 - 2017
- Claret Sentinel System Statistical Analysis awarded by Claret Medical, Inc. 2016 - 2017
- HeartRescue awarded by University of Washington 2016 - 2017
- CABANA-AF Trial awarded by National Institutes of Health 2009 - 2017
- PROMISE Trial: SDCC awarded by National Institutes of Health 2009 - 2015
- ICD Therapy in Patients with Congestive Heart Failure awarded by National Institutes of Health 2009 - 2014
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Cocoros, NM, Pokorney, SD, Haynes, K, Garcia, C, Al-Khalidi, HR, Al-Khatib, SM, Archdeacon, P, Goldsack, JC, Harkins, T, Lin, ND, Martin, D, McCall, D, Nair, V, Parlett, L, Temple, R, McMahill-Walraven, C, Granger, CB, and Platt, R. "FDA-Catalyst-Using FDA's Sentinel Initiative for large-scale pragmatic randomized trials: Approach and lessons learned during the planning phase of the first trial." Clinical Trials (London, England) 16, no. 1 (February 2019): 90-97. Full Text
  - Ambrosy, AP, Stevens, SR, Al-Khalidi, HR, Rouleau, JL, Bouabdallaoui, N, Carson, PE, Adlbrecht, C, Cleland, JGF, Dabrowski, R, Golba, KS, Pina, IL, Sueta, CA, Roy, A, Sopko, G, Bonow, RO, Velazquez, EJ, and STICH Trial Investigators, . "Burden of medical co-morbidities and benefit from surgical revascularization in patients with ischaemic cardiomyopathy." European Journal of Heart Failure (January 30, 2019). Full Text
  - Kochar, A, Al-Khalidi, HR, Doerfler, S, and Granger, CB. "Reply: Delays From First Medical Contact to Revascularization in Patients With ST-Segment Elevation Myocardial Infarction Presenting With Cardiogenic Shock." Jacc. Cardiovascular Interventions 12, no. 1 (January 2019): 107-null. (Letter) Full Text
  - Bouabdallaoui, N, Stevens, SR, Doenst, T, Petrie, MC, Al-Attar, N, Ali, IS, Ambrosy, AP, Barton, AK, Cartier, R, Cherniavsky, A, Demondion, P, Desvigne-Nickens, P, Favaloro, RR, Gradinac, S, Heinisch, P, Jain, A, Jasinski, M, Jouan, J, Kalil, RAK, Menicanti, L, Michler, RE, Rao, V, Smith, PK, Zembala, M, Velazquez, EJ, Al-Khalidi, HR, Rouleau, JL, and STICH Trial Investigators, . "Society of Thoracic Surgeons Risk Score and EuroSCORE-2 Appropriately Assess 30-Day Postoperative Mortality in the STICH Trial and a Contemporary Cohort of Patients With Left Ventricular Dysfunction Undergoing Surgical Revascularization." Circulation. Heart Failure 11, no. 11 (November 2018): e005531-null. Full Text
  - Kochar, A, Al-Khalidi, HR, Hansen, SM, Shavadia, JS, Roettig, ML, Fordyce, CB, Doerfler, S, Gersh, BJ, Henry, TD, Berger, PB, Jollis, JG, and Granger, CB. "Delays in Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction Patients Presenting With Cardiogenic Shock." Jacc. Cardiovascular Interventions 11, no. 18 (September 2018): 1824-1833. Full Text
  - Pellikka, PA, She, L, Holly, TA, Lin, G, Varadarajan, P, Pai, RG, Bonow, RO, Pohost, GM, Panza, JA, Berman, DS, Prior, DL, Asch, FM, Borges-Neto, S, Grayburn, P, Al-Khalidi, HR, Miszalski-Jamka, K, Desvigne-Nickens, P, Lee, KL, Velazquez, EJ, and Oh, JK. "Variability in Ejection Fraction Measured By Echocardiography, Gated Single-Photon Emission Computed Tomography, and Cardiac Magnetic Resonance in Patients With Coronary Artery Disease and Left Ventricular Dysfunction." Jama Network Open 1, no. 4 (August 3, 2018): e181456-null. Full Text
  - Kirchhof, P, Haeusler, KG, Blank, B, De Bono, J, Callans, D, Elvan, A, Fetsch, T, Van Gelder, IC, Gentlesk, P, Grimaldi, M, Hansen, J, Hindricks, G, Al-Khalidi, HR, Massaro, T, Mont, L, Nielsen, JC, Nölker, G, Piccini, JP, De Potter, T, Scherr, D, Schotten, U, Themistoclakis, S, Todd, D, Vijgen, J, and Di Biase, L. "Apixaban in patients at risk of stroke undergoing atrial fibrillation ablation." European Heart Journal 39, no. 32 (August 2018): 2942-2955. Full Text
  - Saito, S, Krucoff, MW, Nakamura, S, Mehran, R, Maehara, A, Al-Khalidi, HR, Rowland, SM, Tasissa, G, Morrell, D, Joseph, D, Okaniwa, Y, Shibata, Y, Bertolet, BD, Rothenberg, MD, Généreux, P, Bezerra, H, and Kong, DF. "Japan-United States of America Harmonized Assessment by Randomized Multicentre Study of OrbusNEich's Combo StEnt (Japan-USA HARMONEE) study: primary results of the pivotal registration study of combined endothelial progenitor cell capture and drug-eluting stent in patients with ischaemic coronary disease and non-ST-elevation acute coronary syndrome." European Heart Journal 39, no. 26 (July 2018): 2460-2468. Full Text
  - Bouabdallaoui, N, Stevens, SR, Doenst, T, Wrobel, K, Bouchard, D, Deja, MA, Michler, RE, Chua, YL, Kalil, RAK, Selzman, CH, Daly, RC, Sun, B, Djokovic, LT, Sopko, G, Velazquez, EJ, Rouleau, JL, Lee, KL, Al-Khalidi, HR, and STICH Trial Investigators, . "Impact of Intubation Time on Survival following Coronary Artery Bypass Grafting: Insights from the Surgical Treatment for Ischemic Heart Failure (STICH) Trial." Journal of Cardiothoracic and Vascular Anesthesia 32, no. 3 (June 2018): 1256-1263. Full Text
  - Packer, DL, Mark, DB, Robb, RA, Monahan, KH, Bahnson, TD, Moretz, K, Poole, JE, Mascette, A, Rosenberg, Y, Jeffries, N, Al-Khalidi, HR, Lee, KL, and CABANA Investigators, . "Catheter Ablation versus Antiarrhythmic Drug Therapy for Atrial Fibrillation (CABANA) Trial: Study Rationale and Design." American Heart Journal 199 (May 2018): 192-199. Full Text
  - Piccini, JP, Connolly, SJ, Abraham, WT, Healey, JS, Steinberg, BA, Al-Khalidi, HR, Dignacco, P, van Veldhuisen, DJ, Sauer, WH, White, M, Wilton, SB, Anand, IS, Dufton, C, Marshall, DA, Aleong, RG, Davis, GW, Clark, RL, Emery, LL, and Bristow, MR. "A genotype-directed comparative effectiveness trial of Bucindolol and metoprolol succinate for prevention of symptomatic atrial fibrillation/atrial flutter in patients with heart failure: Rationale and design of the GENETIC-AF trial." American Heart Journal 199 (May 2018): 51-58. Full Text
  - Jollis, JG, Al-Khalidi, HR, Roettig, ML, Berger, PB, Corbett, CC, Doerfler, SM, Fordyce, CB, Henry, TD, Hollowell, L, Magdon-Ismail, Z, Kochar, A, McCarthy, JJ, Monk, L, O'Brien, P, Rea, TD, Shavadia, J, Tamis-Holland, J, Wilson, BH, Ziada, KM, and Granger, CB. "Impact of Regionalization of ST-Segment-Elevation Myocardial Infarction Care on Treatment Times and Outcomes for Emergency Medical Services-Transported Patients Presenting to Hospitals With Percutaneous Coronary Intervention: Mission: Lifeline Accelerator-2." Circulation 137, no. 4 (January 2018): 376-387. Full Text
  - Prior, DL, Stevens, SR, Al-Khalidi, HR, Holly, TA, Berman, DS, and STICH Investigators, . "The authors' reply to the letter from Kerkhof et al entitled 'The importance of (measuring) the end-systolic volume index in predicting survival'." Heart (British Cardiac Society) 104, no. 2 (January 2018): 1-null. (Letter) Full Text
  - Stewart, RAH, Szalewska, D, Stebbins, A, Al-Khalidi, HR, Cleland, JGH, Rynkiewicz, A, Drazner, MH, White, HD, Mark, DB, Roy, A, Kosevic, D, Rajda, M, Jasinski, M, Leng, CY, Tungsubutra, W, Desvigne-Nickens, P, Velazquez, EJ, and Petrie, MC. "Six-minute walk distance after coronary artery bypass grafting compared with medical therapy in ischaemic cardiomyopathy." Open Heart 5, no. 1 (January 2018): e000752-null. Full Text Open Access Copy
  - Trattner, S, Halliburton, S, Thompson, CM, Xu, Y, Chelliah, A, Jambawalikar, SR, Peng, B, Peters, MR, Jacobs, JE, Ghesani, M, Jang, JJ, Al-Khalidi, H, and Einstein, AJ. "Cardiac-Specific Conversion Factors to Estimate Radiation Effective Dose From Dose-Length Product in Computed Tomography." Jacc. Cardiovascular Imaging 11, no. 1 (January 2018): 64-74. Full Text
  - Sharma, A, Sekaran, NK, Coles, A, Pagidipati, NJ, Hoffmann, U, Mark, DB, Lee, KL, Al-Khalidi, HR, Lu, MT, Pellikka, PA, Trong, QA, and Douglas, PS. "Impact of Diabetes Mellitus on the Evaluation of Stable Chest Pain Patients: Insights From the PROMISE (Prospective Multicenter Imaging Study for Evaluation of Chest Pain) Trial." Journal of the American Heart Association 6, no. 11 (October 31, 2017). Full Text
  - Hinohara, TT, Al-Khalidi, HR, Fordyce, CB, Gu, X, Sherwood, MW, Roettig, ML, Corbett, CC, Monk, L, Tamis-Holland, JE, Berger, PB, Burchenal, JEB, Wilson, BH, Jollis, JG, and Granger, CB. "Impact of Regional Systems of Care on Disparities in Care Among Female and Black Patients Presenting With ST-Segment-Elevation Myocardial Infarction." Journal of the American Heart Association 6, no. 10 (October 24, 2017). Full Text
  - Kragholm, K, Lu, D, Chiswell, K, Al-Khalidi, HR, Roettig, ML, Roe, M, Jollis, J, and Granger, CB. "Improvement in Care and Outcomes for Emergency Medical Service-Transported Patients With ST-Elevation Myocardial Infarction (STEMI) With and Without Prehospital Cardiac Arrest: A Mission: Lifeline STEMI Accelerator Study." Journal of the American Heart Association 6, no. 10 (October 11, 2017). Full Text
  - Vinereanu, D, Al-Khalidi, HR, Rao, MP, He, W, Lopes, RD, Bahit, CM, Ciobanu, AO, Fox, KA, Pokorney, SD, Xian, Y, Jiang, J, Kamath, DY, Berwanger, O, Tajer, C, Huo, Y, Xavier, D, and Granger, CB. "Regional differences in presentation and antithrombotic treatment of patients with atrial fibrillation: Baseline characteristics from a clustered randomized trial to IMProve treatment with AntiCoagulanTs in patients with atrial fibrillation (IMPACT-AF)." American Heart Journal 192 (October 2017): 38-47. Full Text
  - Vinereanu, D, Lopes, RD, Bahit, MC, Xavier, D, Jiang, J, Al-Khalidi, HR, He, W, Xian, Y, Ciobanu, AO, Kamath, DY, Fox, KA, Rao, MP, Pokorney, SD, Berwanger, O, Tajer, C, de Barros E Silva, PGM, Roettig, ML, Huo, Y, Granger, CB, and IMPACT-AF investigators, . "A multifaceted intervention to improve treatment with oral anticoagulants in atrial fibrillation (IMPACT-AF): an international, cluster-randomised trial." Lancet (London, England) 390, no. 10104 (October 2017): 1737-1746. Full Text
  - Lu, MT, Douglas, PS, Udelson, JE, Adami, E, Ghoshhajra, BB, Picard, MH, Roberts, R, Lee, KL, Einstein, AJ, Mark, DB, Velazquez, EJ, Carter, W, Ridner, M, Al-Khalidi, HR, and Hoffmann, U. "Safety of coronary CT angiography and functional testing for stable chest pain in the PROMISE trial: A randomized comparison of test complications, incidental findings, and radiation dose." Journal of Cardiovascular Computed Tomography 11, no. 5 (September 2017): 373-382. Full Text Open Access Copy
  - Prior, DL, Stevens, SR, Holly, TA, Krejca, M, Paraforos, A, Pohost, GM, Byrd, K, Kukulski, T, Jones, RH, Desvigne-Nickens, P, Varadarajan, P, Amanullah, A, Lin, G, Al-Khalidi, HR, Aldea, G, Santambrogio, C, Bochenek, A, Berman, DS, and STICH Trial Investigators, . "Regional left ventricular function does not predict survival in ischaemic cardiomyopathy after cardiac surgery." Heart (British Cardiac Society) 103, no. 17 (September 2017): 1359-1367. Full Text
  - Hess, PL, Al-Khalidi, HR, Friedman, DJ, Mulder, H, Kucharska-Newton, A, Rosamond, WR, Lopes, RD, Gersh, BJ, Mark, DB, Curtis, LH, Post, WS, Prineas, RJ, Sotoodehnia, N, and Al-Khatib, SM. "The Metabolic Syndrome and Risk of Sudden Cardiac Death: The Atherosclerosis Risk in Communities Study." Journal of the American Heart Association 6, no. 8 (August 23, 2017). Full Text
  - Miszalski-Jamka, K, Jefferies, JL, Mazur, W, Głowacki, J, Hu, J, Lazar, M, Gibbs, RA, Liczko, J, Kłyś, J, Venner, E, Muzny, DM, Rycaj, J, Białkowski, J, Kluczewska, E, Kalarus, Z, Jhangiani, S, Al-Khalidi, H, Kukulski, T, Lupski, JR, Craigen, WJ, and Bainbridge, MN. "Novel Genetic Triggers and Genotype-Phenotype Correlations in Patients With Left Ventricular Noncompaction." Circulation. Cardiovascular Genetics 10, no. 4 (August 2017). Full Text
  - Kong, DF, Saito, S, Nakamura, S, Mehran, R, Rowland, SM, Handler, A, Al-Khalidi, HR, and Krucoff, MW. "Rationale and design of the Japan-USA harmonized assessment by randomized, multicenter study of OrbusNEich's combo StEnt (Japan-USA HARMONEE): Assessment of a novel DES platform for percutaneous coronary revascularization in patients with ischemic coronary disease and non-ST-elevation acute coronary syndrome." American heart journal 187 (May 2017): 112-121. Full Text
  - Pai, RG, Varadarajan, P, Rouleau, JL, Stebbins, AL, Velazquez, EJ, Al-Khalidi, HR, and Pohost, GM. "Value of Cardiovascular Magnetic Resonance Imaging-Derived Baseline Left Ventricular Ejection Fraction and Volumes for Precise Risk Stratification of Patients With Ischemic Cardiomyopathy: Insights From the Surgical Treatment for Ischemic Heart Failure (STICH) Trial." JAMA cardiology 2, no. 5 (May 2017): 577-579. Full Text
  - Fordyce, CB, Douglas, PS, Roberts, RS, Hoffmann, U, Al-Khalidi, HR, Patel, MR, Granger, CB, Kostis, J, Mark, DB, Lee, KL, Udelson, JE, and Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) Investigators, . "Identification of Patients With Stable Chest Pain Deriving Minimal Value From Noninvasive Testing: The PROMISE Minimal-Risk Tool, A Secondary Analysis of a Randomized Clinical Trial." Jama Cardiology 2, no. 4 (April 2017): 400-408. Full Text
  - Di Biase, L, Callans, D, Hæusler, KG, Hindricks, G, Al-Khalidi, H, Mont, L, Cosedis Nielsen, J, Piccini, JP, Schotten, U, and Kirchhof, P. "Rationale and design of AXAFA-AFNET 5: an investigator-initiated, randomized, open, blinded outcome assessment, multi-centre trial to comparing continuous apixaban to vitamin K antagonists in patients undergoing atrial fibrillation catheter ablation." Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology 19, no. 1 (January 2017): 132-138. Full Text
  - Fordyce, CB, Al-Khalidi, HR, Jollis, JG, Roettig, ML, Gu, J, Bagai, A, Berger, PB, Corbett, CC, Dauerman, HL, Fox, K, Garvey, JL, Henry, TD, Rokos, IC, Sherwood, MW, Wilson, BH, Granger, CB, and STEMI Systems Accelerator Project, . "Association of Rapid Care Process Implementation on Reperfusion Times Across Multiple ST-Segment-Elevation Myocardial Infarction Networks." Circulation. Cardiovascular Interventions 10, no. 1 (January 2017). Full Text
  - Bedair, K, Hong, Y, Li, J, and Al-Khalidi, HR. "Multivariate frailty models for multi-type recurrent event data and its application to cancer prevention trial." Computational Statistics and Data Analysis 101 (September 1, 2016): 161-173. Full Text
  - Jollis, JG, Al-Khalidi, HR, Roettig, ML, Berger, PB, Corbett, CC, Dauerman, HL, Fordyce, CB, Fox, K, Garvey, JL, Gregory, T, Henry, TD, Rokos, IC, Sherwood, MW, Suter, RE, Wilson, BH, Granger, CB, and Mission: Lifeline STEMI Systems Accelerator Project, . "Regional Systems of Care Demonstration Project: American Heart Association Mission: Lifeline STEMI Systems Accelerator." Circulation 134, no. 5 (August 2016): 365-374. Full Text
  - Povsic, TJ, Henry, TD, Traverse, JH, Fortuin, FD, Schaer, GL, Kereiakes, DJ, Schatz, RA, Zeiher, AM, White, CJ, Stewart, DJ, Jolicoeur, EM, Bass, T, Henderson, DA, Dignacco, P, Gu, Z, Al-Khalidi, HR, Junge, C, Nada, A, Hunt, AS, Losordo, DW, and RENEW Investigators, . "The RENEW Trial: Efficacy and Safety of Intramyocardial Autologous CD34(+) Cell Administration in Patients With Refractory Angina." Jacc. Cardiovascular Interventions 9, no. 15 (August 2016): 1576-1585. Full Text
  - Rao, SV, Zeymer, U, Douglas, PS, Al-Khalidi, H, White, JA, Liu, J, Levy, H, Guetta, V, Gibson, CM, Tanguay, J-F, Vermeersch, P, Roncalli, J, Kasprzak, JD, Henry, TD, Frey, N, Kracoff, O, Traverse, JH, Chew, DP, Lopez-Sendon, J, Heyrman, R, and Krucoff, MW. "Bioabsorbable Intracoronary Matrix for Prevention of Ventricular Remodeling After Myocardial Infarction." Journal of the American College of Cardiology 68, no. 7 (August 2016): 715-723. Full Text
  - Mark, DB, Federspiel, JJ, Cowper, PA, Anstrom, KJ, Hoffmann, U, Patel, MR, Davidson-Ray, L, Daniels, MR, Cooper, LS, Knight, JD, Lee, KL, Douglas, PS, and PROMISE Investigators, . "Economic Outcomes With Anatomical Versus Functional Diagnostic Testing for Coronary Artery Disease." Annals of Internal Medicine 165, no. 2 (July 2016): 94-102. Full Text
  - Mehmood, M, Ambach, SA, Taylor, MD, Jefferies, JL, Raman, SV, Taylor, RJ, Sawani, H, Mathew, J, Mazur, W, Hor, KN, and Al-Khalidi, HR. "Relationship of Right Ventricular Size and Function with Respiratory Status in Duchenne Muscular Dystrophy." Pediatric cardiology 37, no. 5 (June 2016): 878-883. Full Text
  - Mehmood, M, Ambach, SA, Taylor, MD, Jefferies, JL, Raman, SV, Taylor, RJ, Sawnani, H, Mathew, J, Mazur, W, Hor, KN, and Al-Khalidi, HR. "Erratum to: Relationship of Right Ventricular Size and Function with Respiratory Status in Duchenne Muscular Dystrophy." Pediatric cardiology 37, no. 5 (June 2016): 989-. Full Text
  - Rao, MP, Ciobanu, AO, Lopes, RD, Fox, KA, Xian, Y, Pokorney, SD, Al-Khalidi, HR, Jiang, J, Kamath, DY, Berwanger, O, Xavier, D, Bahit, CM, Tajer, C, Vinereanu, D, Huo, Y, and Granger, CB. "A clustered randomized trial to IMProve treatment with AntiCoagulanTs in patients with Atrial Fibrillation (IMPACT-AF): design and rationale." American heart journal 176 (June 2016): 107-113. Full Text
  - Velazquez, EJ, Lee, KL, Jones, RH, Al-Khalidi, HR, Hill, JA, Panza, JA, Michler, RE, Bonow, RO, Doenst, T, Petrie, MC, Oh, JK, She, L, Moore, VL, Desvigne-Nickens, P, Sopko, G, Rouleau, JL, and STICHES Investigators, . "Coronary-Artery Bypass Surgery in Patients with Ischemic Cardiomyopathy." The New England Journal of Medicine 374, no. 16 (April 3, 2016): 1511-1520. Full Text
  - Garber, AM, Mentz, RJ, Al-Khalidi, HR, Shaw, LK, Fiuzat, M, O'Connor, CM, and Velazquez, EJ. "Clinical predictors and outcomes of patients with left ventricular thrombus following ST-segment elevation myocardial infarction." Journal of thrombosis and thrombolysis 41, no. 3 (April 2016): 365-373. Full Text
  - Jolicœur, EM, Dunning, A, Castelvecchio, S, Dabrowski, R, Waclawiw, MA, Petrie, MC, Stewart, R, Jhund, PS, Desvigne-Nickens, P, Panza, JA, Bonow, RO, Sun, B, San, TR, Al-Khalidi, HR, Rouleau, JL, Velazquez, EJ, and Cleland, JGF. "Importance of angina in patients with coronary disease, heart failure, and left ventricular systolic dysfunction: insights from STICH." Journal of the American College of Cardiology 66, no. 19 (November 2015): 2092-2100. Full Text
  - Rao, SV, Zeymer, U, Douglas, PS, Al-Khalidi, H, Liu, J, Gibson, CM, Harrison, RW, Joseph, DS, Heyrman, R, and Krucoff, MW. "A randomized, double-blind, placebo-controlled trial to evaluate the safety and effectiveness of intracoronary application of a novel bioabsorbable cardiac matrix for the prevention of ventricular remodeling after large ST-segment elevation myocardial infarction: Rationale and design of the PRESERVATION I trial." American heart journal 170, no. 5 (November 2015): 929-937. Full Text
  - Velazquez, EJ, Samad, Z, Al-Khalidi, HR, Sangli, C, Grayburn, PA, Massaro, JM, Stevens, SR, Feldman, TE, and Krucoff, MW. "The MitraClip and survival in patients with mitral regurgitation at high risk for surgery: A propensity-matched comparison." American heart journal 170, no. 5 (November 2015): 1050-1059.e3. Full Text
  - Mehmood, M, Hor, KN, Al-Khalidi, HR, Benson, DW, Jefferies, JL, Taylor, MD, Egnaczyk, GF, Raman, SV, Basu, SK, Cripe, LH, Germann, J, and Mazur, W. "Comparison of right and left ventricular function and size in Duchenne muscular dystrophy." European journal of radiology 84, no. 10 (October 2015): 1938-1942. Full Text
  - Samad, Z, Shaw, LK, Phelan, M, Ersboll, M, Risum, N, Al-Khalidi, HR, Glower, DD, Milano, CA, Alexander, JH, O'Connor, CM, Wang, A, and Velazquez, EJ. "Management and outcomes in patients with moderate or severe functional mitral regurgitation and severe left ventricular dysfunction." European Heart Journal 36, no. 40 (October 2015): 2733-2741. Full Text
  - Wrobel, K, Stevens, SR, Jones, RH, Selzman, CH, Lamy, A, Beaver, TM, Djokovic, LT, Wang, N, Velazquez, EJ, Sopko, G, Kron, IL, DiMaio, JM, Michler, RE, Lee, KL, Yii, M, Leng, CY, Zembala, M, Rouleau, JL, Daly, RC, and Al-Khalidi, HR. "Influence of Baseline Characteristics, Operative Conduct, and Postoperative Course on 30-Day Outcomes of Coronary Artery Bypass Grafting Among Patients With Left Ventricular Dysfunction: Results From the Surgical Treatment for Ischemic Heart Failure (STICH) Trial." Circulation 132, no. 8 (August 2015): 720-730. Full Text
  - Held, C, Hylek, EM, Alexander, JH, Hanna, M, Lopes, RD, Wojdyla, DM, Thomas, L, Al-Khalidi, H, Alings, M, Xavier, D, Ansell, J, Goto, S, Ruzyllo, W, Rosenqvist, M, Verheugt, FWA, Zhu, J, Granger, CB, and Wallentin, L. "Clinical outcomes and management associated with major bleeding in patients with atrial fibrillation treated with apixaban or warfarin: insights from the ARISTOTLE trial." European Heart Journal 36, no. 20 (May 2015): 1264-1272. Full Text
  - Pun, PH, Hellkamp, AS, Sanders, GD, Middleton, JP, Hammill, SC, Al-Khalidi, HR, Curtis, LH, Fonarow, GC, and Al-Khatib, SM. "Primary prevention implantable cardioverter defibrillators in end-stage kidney disease patients on dialysis: a matched cohort study." Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 30, no. 5 (May 2015): 829-835. Full Text
  - Póvoa, P, Salluh, JIF, Martinez, ML, Guillamat-Prats, R, Gallup, D, Al-Khalidi, HR, Thompson, BT, Ranieri, VM, and Artigas, A. "Clinical impact of stress dose steroids in patients with septic shock: insights from the PROWESS-Shock trial." Critical Care 19 (April 28, 2015): 193-null. Full Text
  - Douglas, PS, Hoffmann, U, Patel, MR, Mark, DB, Al-Khalidi, HR, Cavanaugh, B, Cole, J, Dolor, RJ, Fordyce, CB, Huang, M, Khan, MA, Kosinski, AS, Krucoff, MW, Malhotra, V, Picard, MH, Udelson, JE, Velazquez, EJ, Yow, E, Cooper, LS, Lee, KL, and PROMISE Investigators, . "Outcomes of anatomical versus functional testing for coronary artery disease." The New England Journal of Medicine 372, no. 14 (April 2015): 1291-1300. Full Text
  - Pokorney, SD, Hellkamp, AS, Yancy, CW, Curtis, LH, Hammill, SC, Peterson, ED, Masoudi, FA, Bhatt, DL, Al-Khalidi, HR, Heidenreich, PA, Anstrom, KJ, Fonarow, GC, and Al-Khatib, SM. "Primary prevention implantable cardioverter-defibrillators in older racial and ethnic minority patients." Circulation. Arrhythmia and Electrophysiology 8, no. 1 (February 2015): 145-151. Full Text
  - Zeitler, EP, Hellkamp, AS, Fonarow, GC, Hammill, SC, Curtis, LH, Hernandez, AF, Al-Khalidi, HR, Curtis, JP, Heidenreich, PA, Anstrom, KJ, Peterson, ED, Mark, DB, Hammill, BG, Sanders, GD, and Al-Khatib, SM. "Primary prevention implantable cardioverter-defibrillators and survival in older women." Jacc. Heart Failure 3, no. 2 (February 2015): 159-167. Full Text
  - Hor, KN, Kissoon, N, Mazur, W, Gupta, R, Ittenbach, RF, Al-Khalidi, HR, Cripe, LH, Raman, SV, Puchalski, MD, Gottliebson, WM, and Benson, DW. "Regional circumferential strain is a biomarker for disease severity in duchenne muscular dystrophy heart disease: a cross-sectional study." Pediatric cardiology 36, no. 1 (January 2015): 111-119. Full Text
  - Miszalski-Jamka, T, Szczeklik, W, Sokołowska, B, Karwat, K, Miszalski-Jamka, K, Jaźwiec, P, Małek, ŁA, Al-Khalidi, H, Schulz-Menger, J, Mavrogeni, S, Mahr, A, Mazur, W, Kereiakes, DJ, and Musiał, J. "Noncorticosteroid immunosuppression limits myocardial damage and contractile dysfunction in eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)." Journal of the American College of Cardiology 65, no. 1 (January 2015): 103-105. (Letter) Full Text
  - Póvoa, P, Salluh, JI, Martinez, ML, Guillamat-Prats, R, Gallup, D, Al-Khalidi, HR, Thompson, BT, Ranieri, VM, and Artigas, A. "Clinical impact of stress dose steroids in patients with septic shock: Insights from the PROWESS-Shock trial." Critical Care (2015). Full Text
  - Hess, PL, Hellkamp, AS, Peterson, ED, Sanders, GD, Al-Khalidi, HR, Curtis, LH, Hammill, BG, Pun, PH, Curtis, JP, Anstrom, KJ, Hammill, SC, and Al-Khatib, SM. "Survival after primary prevention implantable cardioverter-defibrillator placement among patients with chronic kidney disease." Circulation. Arrhythmia and Electrophysiology 7, no. 5 (October 2014): 793-799. Full Text
  - Newby, LK, Marber, MS, Melloni, C, Sarov-Blat, L, Aberle, LH, Aylward, PE, Cai, G, de Winter, RJ, Hamm, CW, Heitner, JF, Kim, R, Lerman, A, Patel, MR, Tanguay, J-F, Lepore, JJ, Al-Khalidi, HR, Sprecher, DL, Granger, CB, and SOLSTICE Investigators, . "Losmapimod, a novel p38 mitogen-activated protein kinase inhibitor, in non-ST-segment elevation myocardial infarction: a randomised phase 2 trial." Lancet (London, England) 384, no. 9949 (September 2014): 1187-1195. Full Text
  - Hor, KN, Kissoon, N, Mazur, W, Gupta, R, Ittenbach, RF, Al-Khalidi, HR, Cripe, LH, Raman, SV, Puchalski, MD, Gottliebson, WM, and Benson, DW. "Regional circumferential strain is a biomarker for disease severity in duchenne muscular dystrophy heart disease: A cross-sectional study." Pediatric Cardiology 36, no. 1 (August 2, 2014): 111-119. Full Text
  - Al-Khatib, SM, Hellkamp, AS, Fonarow, GC, Mark, DB, Curtis, LH, Hernandez, AF, Anstrom, KJ, Peterson, ED, Sanders, GD, Al-Khalidi, HR, Hammill, BG, Heidenreich, PA, and Hammill, SC. "Association between prophylactic implantable cardioverter-defibrillators and survival in patients with left ventricular ejection fraction between 30% and 35%." Jama 311, no. 21 (June 2014): 2209-2215. Full Text
  - Douglas, PS, Hoffmann, U, Lee, KL, Mark, DB, Al-Khalidi, HR, Anstrom, K, Dolor, RJ, Kosinski, A, Krucoff, MW, Mudrick, DW, Patel, MR, Picard, MH, Udelson, JE, Velazquez, EJ, Cooper, L, and PROMISE investigators, . "PROspective Multicenter Imaging Study for Evaluation of chest pain: rationale and design of the PROMISE trial." American Heart Journal 167, no. 6 (June 2014): 796-803.e1. Full Text
  - "Regional systems of care demonstration project: Mission: Lifeline STEMI Systems Accelerator: Design and methodology." American Heart Journal 167, no. 1 (January 1, 2014). Full Text
  - Bagai, A, Al-Khalidi, HR, Sherwood, MW, Muñoz, D, Roettig, ML, Jollis, JG, and Granger, CB. "Regional systems of care demonstration project: Mission: Lifeline STEMI Systems Accelerator: design and methodology." American Heart Journal 167, no. 1 (January 2014): 15-21.e3. Full Text
  - Douglas, PS, Hoffmann, U, Lee, KL, Mark, DB, Al-Khalidi, HR, Anstrom, K, Dolor, RJ, Kosinski, A, Krucoff, MW, Mudrick, DW, Patel, MR, Picard, MH, Udelson, JE, Velazquez, EJ, and Cooper, L. "PROspective Multicenter Imaging Study for Evaluation of chest pain: Rationale and design of the PROMISE trial." American Heart Journal 167, no. 6 (January 1, 2014). Full Text
  - Newby, LK, Marber, MS, Melloni, C, Sarov-Blat, L, Aberle, LH, Aylward, PE, Cai, G, De Winter, RJ, Hamm, CW, Heitner, JF, Kim, R, Lerman, A, Patel, MR, Tanguay, JF, Lepore, JJ, Al-Khalidi, HR, Sprecher, DL, and Granger, CBI. "Losmapimod, a novel p38 mitogen-activated protein kinase inhibitor, in non-ST-segment elevation myocardial infarction: A randomised phase 2 trial." The Lancet 384, no. 9949 (January 1, 2014): 1187-1195. Full Text
  - Hor, KN, Taylor, MD, Al-Khalidi, HR, Cripe, LH, Raman, SV, Jefferies, JL, O'Donnell, R, Benson, DW, and Mazur, W. "Prevalence and distribution of late gadolinium enhancement in a large population of patients with Duchenne muscular dystrophy: effect of age and left ventricular systolic function." Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance 15 (December 21, 2013): 107-null. Full Text
  - Michler, RE, Rouleau, JL, Al-Khalidi, HR, Bonow, RO, Pellikka, PA, Pohost, GM, Holly, TA, Oh, JK, Dagenais, F, Milano, C, Wrobel, K, Pirk, J, Ali, IS, Jones, RH, Velazquez, EJ, Lee, KL, Di Donato, M, and STICH Trial Investigators, . "Insights from the STICH trial: change in left ventricular size after coronary artery bypass grafting with and without surgical ventricular reconstruction." The Journal of Thoracic and Cardiovascular Surgery 146, no. 5 (November 2013): 1139-1145.e6. Full Text
  - Bagai, A, Al-Khalidi, HR, Muñoz, D, Monk, L, Roettig, ML, Corbett, CC, Garvey, JL, Wilson, BH, Granger, CB, and Jollis, JG. "Bypassing the emergency department and time to reperfusion in patients with prehospital ST-segment-elevation: findings from the reperfusion in acute myocardial infarction in Carolina Emergency Departments project." Circ Cardiovasc Interv 6, no. 4 (August 2013): 399-406. Full Text Link to Item
  - Al-Khatib, SM, Hellkamp, A, Bardy, GH, Hammill, S, Hall, WJ, Mark, DB, Anstrom, KJ, Curtis, J, Al-Khalidi, H, Curtis, LH, Heidenreich, P, Peterson, ED, Sanders, G, Clapp-Channing, N, Lee, KL, and Moss, AJ. "Survival of patients receiving a primary prevention implantable cardioverter-defibrillator in clinical practice vs clinical trials." Jama 309, no. 1 (January 2013): 55-62. Full Text
  - Michler, RE, Rouleau, JL, Al-Khalidi, HR, Bonow, RO, Pellikka, PA, Pohost, GM, Holly, TA, Oh, JK, Dagenais, F, Milano, C, and al, E. "Insights from the STICH trial: Change in left ventricular size after coronary artery bypass grafting with and without surgical ventricular reconstruction." Journal of Thoracic and Cardiovascular Surgery 146, no. 5 (2013): 1139-1145.e6. Full Text
  - Muñoz, D, Roettig, ML, Monk, L, Al-Khalidi, H, Jollis, JG, and Granger, CB. "Transport time and care processes for patients transferred with ST-segment-elevation myocardial infarction: the reperfusion in acute myocardial infarction in Carolina emergency rooms experience." Circulation. Cardiovascular Interventions 5, no. 4 (August 7, 2012): 555-562. Full Text
  - Jollis, JG, Al-Khalidi, HR, Monk, L, Roettig, ML, Garvey, JL, Aluko, AO, Wilson, BH, Applegate, RJ, Mears, G, Corbett, CC, Granger, CB, and Regional Approach to Cardiovascular Emergencies (RACE) Investigators, . "Expansion of a regional ST-segment-elevation myocardial infarction system to an entire state." Circulation 126, no. 2 (July 10, 2012): 189-195. Full Text Link to Item
  - Truffa, AAM, Granger, CB, White, KR, Newby, LK, Mehta, RH, Hochman, JS, Patel, MR, Pieper, KS, Al-Khalidi, HR, Armstrong, PW, and Lopes, RD. "Serious infection after acute myocardial infarction: incidence, clinical features, and outcomes." JACC Cardiovasc Interv 5, no. 7 (July 2012): 769-776. Full Text Link to Item
  - Ranieri, VM, Thompson, BT, Barie, PS, Dhainaut, J-F, Douglas, IS, Finfer, S, Gårdlund, B, Marshall, JC, Rhodes, A, Artigas, A, Payen, D, Tenhunen, J, Al-Khalidi, HR, Thompson, V, Janes, J, Macias, WL, Vangerow, B, Williams, MD, and PROWESS-SHOCK Study Group, . "Drotrecogin alfa (activated) in adults with septic shock." The New England Journal of Medicine 366, no. 22 (May 22, 2012): 2055-2064. Full Text
  - Al-Khatib, SM, Hellkamp, AS, Hernandez, AF, Fonarow, GC, Thomas, KL, Al-Khalidi, HR, Heidenreich, PA, Hammill, S, Yancy, C, Peterson, ED, and Get With the Guidelines Steering Committee and Hospitals, . "Trends in use of implantable cardioverter-defibrillator therapy among patients hospitalized for heart failure: have the previously observed sex and racial disparities changed over time?." Circulation 125, no. 9 (March 2012): 1094-1101. Full Text
  - Mazur, W, Hor, KN, Germann, JT, Fleck, RJ, Al-Khalidi, HR, Wansapura, JP, Chung, ES, Taylor, MD, Jefferies, JL, Benson, DW, and Gottliebson, WM. "Patterns of left ventricular remodeling in patients with Duchenne Muscular Dystrophy: a cardiac MRI study of ventricular geometry, global function, and strain." Int J Cardiovasc Imaging 28, no. 1 (January 2012): 99-107. Full Text Link to Item
  - Al-Khalidi, HR, Hong, Y, Fleming, TR, and Therneau, TM. "Insights on the robust variance estimator under recurrent-events model." Biometrics 67, no. 4 (December 2011): 1564-1572. Full Text Link to Item
  - Samad, Z, Yow, E, Shaw, LK, Al-Khalidi, HR, Arges, K, Toptine, JH, Krucoff, M, Wang, A, Jollis, JG, and Velazquez, EJ. "Prevalence and Natural History of Moderate or Severe Mitral Regurgitation: an Observational Study from a Single Center." CIRCULATION 124, no. 21 (November 22, 2011). Link to Item
  - Hor, KN, Mazur, W, Taylor, MD, Al-Khalidi, HR, Cripe, LH, Jefferies, JL, Raman, SV, Chung, ES, Kinnett, KJ, Williams, K, Gottliebson, WM, and Benson, DW. "Effects of steroids and angiotensin converting enzyme inhibition on circumferential strain in boys with Duchenne muscular dystrophy: a cross-sectional and longitudinal study utilizing cardiovascular magnetic resonance." Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance 13 (October 19, 2011): 60-null. Full Text
  - Granger, CB, Alexander, JH, McMurray, JJV, Lopes, RD, Hylek, EM, Hanna, M, Al-Khalidi, HR, Ansell, J, Atar, D, Avezum, A, Bahit, MC, Diaz, R, Easton, JD, Ezekowitz, JA, Flaker, G, Garcia, D, Geraldes, M, Gersh, BJ, Golitsyn, S, Goto, S, Hermosillo, AG, Hohnloser, SH, Horowitz, J, Mohan, P, Jansky, P, Lewis, BS, Lopez-Sendon, JL, Pais, P, Parkhomenko, A, Verheugt, FWA, Zhu, J, Wallentin, L, and ARISTOTLE Committees and Investigators, . "Apixaban versus warfarin in patients with atrial fibrillation." The New England Journal of Medicine 365, no. 11 (September 2011): 981-992. Full Text
  - Bhatti, S, Hakeem, A, Yousuf, MA, Al-Khalidi, HR, Mazur, W, and Shizukuda, Y. "Diagnostic performance of computed tomography angiography for differentiating ischemic vs nonischemic cardiomyopathy." J Nucl Cardiol 18, no. 3 (May 2011): 407-420. Full Text Link to Item
  - Hor, KN, Wansapura, JP, Al-Khalidi, HR, Gottliebson, WM, Taylor, MD, Czosek, RJ, Nagueh, SF, Akula, N, Chung, ES, Benson, WD, and Mazur, W. "Presence of mechanical dyssynchrony in Duchenne muscular dystrophy." Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance 13 (January 2011): 12-null. Full Text
  - Hor, KN, Gottliebson, WM, Carson, C, Wash, E, Cnota, J, Fleck, R, Wansapura, J, Klimeczek, P, Al-Khalidi, HR, Chung, ES, Benson, DW, and Mazur, W. "Comparison of magnetic resonance feature tracking for strain calculation with harmonic phase imaging analysis." Jacc. Cardiovascular Imaging 3, no. 2 (February 2010): 144-151. Full Text
  - Jolicoeur, EM, O'Neill, WW, Hellkamp, A, Hamm, CW, Holmes, DR, Al-Khalidi, HR, Patel, MR, Van de Werf, FJ, Pieper, K, Armstrong, PW, Granger, CB, and APEX-AMI Investigators, . "Transfusion and mortality in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention." Eur Heart J 30, no. 21 (November 2009): 2575-2583. Full Text Link to Item
  - Dorian, P, Al-Khalidi, HR, Hohnloser, SH, Brum, JM, Dunnmon, PM, Pratt, CM, Holroyde, MJ, Kowey, P, and Shock Inhibition Evaluation with Azimilide Investigators, . "Azimilide reduces emergency department visits and hospitalizations in patients with an implantable cardioverter-defibrillator in a placebo-controlled clinical trial." J Am Coll Cardiol 52, no. 13 (September 23, 2008): 1076-1083. Full Text Link to Item
  - "Zoledronate, fractures, and mortality after hip fracture [4]." New England Journal of Medicine 358, no. 9 (February 28, 2008): 968-969. (Letter)
  - Karam, R, Al-Khalidi, H, and Steinbuch, M. "Zoledronate, fractures, and mortality after hip fracture [3]." New England Journal of Medicine 358, no. 9 (February 28, 2008): 968-null. (Letter)
  - Karam, R, Al-Khalidi, H, and Steinbuch, M. "Zoledronate, fractures, and mortality after hip fracture." The New England Journal of Medicine 358, no. 9 (February 2008): 969-null. (Letter) Full Text
  - Tjandrawidjaja, MC, Fu, Y, Al-Khalidi, H, Todaro, TG, Adams, P, Werf, FVD, Granger, CB, and Armstrong, PW. "Failure of investigator adherence to electrocardiographic entry criteria is frequent and influences clinical outcomes: Lessons from APEX-AMI." European Heart Journal 28, no. 23 (2007): 2850-2857. Full Text
  - Hohnloser, SH, Al-Khalidi, HR, Pratt, CM, Brum, JM, Tatla, DS, Tchou, P, Dorian, P, and SHock Inhibition Evaluation with AzimiLiDe (SHIELD) Investigators, . "Electrical storm in patients with an implantable defibrillator: incidence, features, and preventive therapy: insights from a randomized trial." European Heart Journal 27, no. 24 (December 2006): 3027-3032. Full Text
  - Pratt, CM, Al-Khalidi, HR, Brum, JM, Holroyde, MJ, Schwartz, PJ, Marcello, SR, Borggrefe, M, Dorian, P, Camm, AJ, and Azimilide Trials Investigators, . "Cumulative experience of azimilide-associated torsades de pointes ventricular tachycardia in the 19 clinical studies comprising the azimilide database." Journal of the American College of Cardiology 48, no. 3 (August 2006): 471-477. Full Text
  - Armstrong, PW, Adams, PX, Al-Khalidi, HR, Hamm, C, Holmes, D, O'Neill, W, Todaro, TG, Vahanian, A, Van de Werf, F, Granger, CB, and APEX-AMI Steering Committee, . "Assessment of Pexelizumab in Acute Myocardial Infarction (APEX AMI): a multicenter, randomized, double-blind, parallel-group, placebo-controlled study of pexelizumab in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention." Am Heart J 149, no. 3 (March 2005): 402-407. Full Text Link to Item
  - Pratt, CM, Dorian, P, Al-Khalidi, HR, Brum, JM, Borggrefe, M, Tatla, DS, Brachmann, J, Myerburg, RJ, Cannom, DS, Holroyde, MJ, van der Laan, M, Hohnloser, SH, and SHIELD Investigators, . "Design of the SHock Inhibition Evaluation with Azimilide (SHIELD) study: a novel method to assess antiarrhythmic drug effect in patients with an implantable cardioverter-defibrillator." Am J Cardiol 95, no. 2 (January 15, 2005): 274-276. Full Text Link to Item
  - Dorian, P, Borggrefe, M, Al-Khalidi, HR, Hohnloser, SH, Brum, JM, Tatla, DS, Brachmann, J, Myerburg, RJ, Cannom, DS, van der Laan, M, Holroyde, MJ, Singer, I, Pratt, CM, and SHock Inhibition Evaluation with azimiLiDe (SHIELD) Investigators, . "Placebo-controlled, randomized clinical trial of azimilide for prevention of ventricular tachyarrhythmias in patients with an implantable cardioverter defibrillator." Circulation 110, no. 24 (December 2004): 3646-3654. Full Text
  - Pratt, CM, Singh, SN, Al-Khalidi, HR, Brum, JM, Holroyde, MJ, Marcello, SR, Schwartz, PJ, Camm, AJ, and ALIVE Investigators, . "The efficacy of azimilide in the treatment of atrial fibrillation in the presence of left ventricular systolic dysfunction: results from the Azimilide Postinfarct Survival Evaluation (ALIVE) trial." J Am Coll Cardiol 43, no. 7 (April 7, 2004): 1211-1216. Full Text Link to Item
  - Camm, AJ, Pratt, CM, Schwartz, PJ, Al-Khalidi, HR, Spyt, MJ, Holroyde, MJ, Karam, R, Sonnenblick, EH, Brum, JMG, and AzimiLide post Infarct surVival Evaluation (ALIVE) Investigators, . "Mortality in patients after a recent myocardial infarction: a randomized, placebo-controlled trial of azimilide using heart rate variability for risk stratification." Circulation 109, no. 8 (March 2, 2004): 990-996. Full Text Link to Item
  - Singer, I, Al-Khalidi, H, Niazi, I, Tchou, P, Simmons, T, Henthorn, R, Holroyde, M, and Brum, J. "Azimilide Decreases Recurrent Ventricular Tachyarrhythmias in Patients with Implantable Cardioverter Defibrillators." Journal of the American College of Cardiology 43, no. 1 (2004): 39-43. Full Text
  - Al-Khalidi, HR, Brum, JM, Karam, R, Camm, AJ, Sonnenblick, E, Schwartz, PJ, Ruzyllo, W, Holroyde, MJ, and Pratt, CM. "The ALIVE study: heart rate variability prospectively identifies patients at high risk of death after myocardial infarction." EUROPEAN HEART JOURNAL 22 (September 2001): 696-+. Link to Item
  - Al-Khalidi, HR, Camm, AJ, Brum, JM, Ruda, M, Schwartz, PJ, Spyt, MJ, Pratt, CM, and Holroyde, MJ. "Low heart rate variability (triangular index method) predicts mortality independent of beta-blocker usage, LVEF, and other factors: ALIVE trial early findings." EUROPEAN HEART JOURNAL 22 (September 2001): 701-701. Link to Item
  - Al-Khalidi, HR, Pratt, CM, Brum, JM, Camm, AJ, Schwartz, PJ, Holroyde, MJ, Hislop, CM, and Elkayam, U. "Baseline characteristics that identify patients at high risk of death following myocardial infarction. Preliminary findings from the ALIVE trial." EUROPEAN HEART JOURNAL 22 (September 2001): 700-700. Link to Item
  - Brooks, RR, Drexler, AP, Maynard, AE, Al-Khalidi, H, and Kostreva, DR. "Proarrhythmia of azimilide and other class III antiarrhythmic agents in the adrenergically stimulated rabbit." Proceedings of the Society for Experimental Biology and Medicine 223, no. 2 (2000): 183-189.
  - Corey, A, Al-Khalidi, H, Brezovic, C, Marcello, S, Parekh, N, Taylor, K, and Karam, R. "Azimilide pharmacokinetics and pharmacodynamics upon multiple oral dosing." Biopharmaceutics & drug disposition 20, no. 2 (March 1999): 59-68. Full Text
  - Corey, A, Al-Khalidi, H, Brezovic, C, Marcello, S, Parekh, N, Taylor, K, and Karam, R. "Azimilide pharmacokinetics and pharmacodynamics upon multiple oral dosing." Biopharmaceutics & Drug Disposition 20, no. 2 (March 1999): 59-68. Full Text
  - Corey, A, Al-Khalidi, H, Brezovic, C, Marcello, S, Parekh, N, Taylor, K, and Karam, R. "Azimilide pharmacokinetics and pharmacodynamics upon multiple oral dosing." Clinical Pharmacology and Therapeutics 61, no. 2 (December 1, 1997): 205-null.
  - Al-Khalidi, HR, and Schnell, DJ. "Application of a continuous-time Markov chain to a preclinical study." Drug Information Journal 31, no. 2 (1997): 607-613.
  - Shen, LZ, and Al-Khalidi, HR. "Application of boundary calculation methodologies to group sequential testing in general parametric models." Communications in Statistics Theory and Methods 26, no. 9 (January 1, 1997): 2173-2190. Full Text
  - al-Khalidi, HR, and Schnell, DJ. "Application of a continuous-time markov chain to a preclinical study." Therapeutic Innovation &Amp; Regulatory Science 31, no. 2 (January 1, 1997): 607-613. Full Text
  - Drexler, AP, Ai-Khalidi, H, Maynard, AE, Johnson, NC, Joroensen, RL, Brooks, RR, and Kostreva, PR. "Comparison of azimilide dihydrochloride (NE-10064) and selected class III antiarrhythmic agents in a rabbit model of proarrhythmia." Faseb Journal 10, no. 3 (December 1, 1996).
  - Brint, SU, Al-Khalidi, HR, Vatel, B, and Hier, DB. "MCA flow asymmetry is a marker for cerebrovascular disease." Neurol Res 18, no. 2 (April 1996): 163-167. Link to Item
  - Al-Khalidi, HR. "On the misspecification of a lognormal distribution." Communications in Statistics Theory and Methods 23, no. 8 (January 1, 1994): 2351-2365. Full Text
  - Al-Khalidi, HR, and Parsa, AR. "Some aspects of maximum likelihood estimation of multistage cancer dose-response odels with application." Communications in Statistics Theory and Methods 22, no. 12 (January 1993): 3377-3392. Full Text
  - Holiday, DB, and McLarty, JW. "Comparing time trends in a two-arm longitudinal study with an ordinal categorical response." Communications in Statistics Theory and Methods 22, no. 12 (January 1, 1993): 3569-3590. Full Text
  - Al-Khalidi, HR, and Hwang, LJ. "Some pitfalls of tests of separate families of hypotheses: Normality vs. lognormality." Communications in Statistics Theory and Methods 20, no. 8 (January 1, 1991): 2505-2528. Full Text
- Conference Papers
  - Jollis, JG, Al-Khalidi, HR, Roettig, ML, Monk, L, Berger, PB, Corbett, C, Doerfler, S, Fordyce, C, Henry, TD, Kochar, A, O'Brien, P, Shavadia, J, Wilson, BH, and Granger, CB. "Regional STEMI Systems of Care: Results of the Mission: Lifeline STEMI ACCELERATOR-2 Study." December 12, 2017. Link to Item
  - Lee, KL, Roberts, RS, Mark, DB, Al-Khalidi, HR, Boineau, R, Rosenberg, Y, Stylianou, M, and Lamas, GA. "Behind the Looking Glass: Comparing Time to First Event versus Multiple Events Analyses in a Post-myocardial Infarction Clinical Trial." November 10, 2015. Link to Item
  - Lu, MT, Douglas, PS, Udelson, JE, Adami, EC, Ghoshhajra, BB, Picard, MH, Roberts, R, Lee, KL, Einstein, AJ, Mark, DB, Velazquez, EJ, Carter, W, Ridner, M, Al-Khalidi, HR, and Hoffmann, U. "Safety of Anatomic versus Functional Diagnostic Testing: Insights From the PROMISE Trial (PROspective Multicenter Imaging Study for Evaluation of Chest Pain)." November 10, 2015. Link to Item
  - Sherwood, MW, Al-Khalidi, HR, Jollis, JG, Roettig, ML, Berger, PB, Corbett, CC, Dauerman, HL, Fox, K, Garvey, JL, Henry, TD, Rokos, IC, Wilson, BH, and Granger, CB. "Developing Regional STEMI Systems of Care: Final Results of the Mission: Lifeline STEMI ACCELERATOR Study." Scientific Sessions of the American-Heart-Association and American-Stroke-Association / Resuscitation Science Symposium. Chicago, IL. November 15, 2014 - November 19, 2014. LIPPINCOTT WILLIAMS & WILKINS, December 2, 2014. Link to Item
  - Garber, AM, Mentz, RJ, Shaw, LK, Al-Khalidi, HR, Fiuzat, M, O'Connors, C, and Velazquez, EJ. "Predictors of Left Ventricular Thrombus Following ST-Segment Elevation Myocardial Infarction: Findings From the Duke Databank of Cardiovascular Disease and the Duke Echocardiography Databank." November 26, 2013. Link to Item
  - Granger, CB, Monk, LM, Roettig, ML, Al-Khalidi, HR, Applegate, RJ, Corbett, CC, Garvey, JL, Hathawy, WR, Wilson, BH, and Jollis, JG. "State-Wide Care is Improved in the Reperfusion of Acute MI in Carolina Emergency Department Emergency Response (RACE-ER) Systems Improvement Program." November 23, 2010. Link to Item
  - Dorian, P, Al-khalidi, HR, Hohnloser, SH, Brum, JM, Tatla, DS, van der Laan, M, and Pratt, CM. "Analysis of all recurrent events is superior to the time-to-first event in assessment of drug therapy to prevent ICD therapies." September 2005. Link to Item
  - Dorian, P, Hohnloser, S, Al-Khalidi, HR, Brum, JM, Borggrefe, M, Tatla, DS, Brachmann, J, Myerburg, R, Cannom, D, Vanderlaan, M, Holroyde, MJ, Pratt, CM, and Investigators, SHIELD. "SHock Inhibition Evaluation with AzimiLiDe (SHIELD): A randomized placebo controlled trial of azimilide in reducing ICD therapies." April 5, 2005. Link to Item
Teaching & Mentoring
Recent Courses
- BIOSTAT 705: Applied Biostatistical Methods II 2019

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