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Igor Klem

Associate Professor of Medicine
Medicine, Cardiology
Duke Box 3943, Durham, NC 27710
Trent Drive, Duke Clinic, Orange Zone, Rm 4229, Durham, NC 27710

Current Appointments & Affiliations


Associate Professor of Medicine · 2019 - Present Medicine, Cardiology, Medicine

Recent Publications


Accuracy of left ventricular mechanical dyssynchrony indices for mechanical characteristics of left bundle branch block using cardiovascular magnetic resonance feature tracking.

Journal Article Eur Heart J Cardiovasc Imaging · March 3, 2025 AIMS: More than 90% of patients with left bundle branch block (LBBB) and reduced left ventricular (LV) ejection fraction have LV dyssynchrony and a high probability of response to cardiac resynchronization therapy (CRT). A subgroup of patients with non-spe ... Full text Link to item Cite

Stress cardiovascular magnetic resonance imaging in intermediate-risk emergency department patients with abnormal high-sensitivity troponin.

Journal Article J Cardiovasc Magn Reson · January 28, 2025 BACKGROUND: Patients presenting to the emergency department (ED) with chest pain often have abnormal high-sensitivity troponin (hsTn). However, only about 5% have an acute coronary syndrome. We aimed to assess the safety, feasibility, and utility of a clin ... Full text Link to item Cite

Cardiovascular impact of near complete estrogen deprivation in premenopausal women with breast cancer: The CROWN study.

Journal Article Am Heart J · January 2024 Survival with operable breast cancer has improved markedly in recent decades, however, treatment-related cardiovascular toxicities threaten to offset these gains. Ovarian function suppression paired with aromatase inhibition, for premenopausal women with h ... Full text Link to item Cite
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Recent Grants


CMR evaluation of ED patients presenting with chest pain, abnormal troponin values and low HEART-Score

Clinical TrialPrincipal Investigator · Awarded by Bayer HealthCare, LLC · 2021 - 2024

Cardiovascular Impact of Near-complete Estrogen Deprivation for Breast Cancer

ResearchInvestigator · Awarded by Wake Forest University School Of Medicine · 2022 - 2023

Medical Images, HTML5, and Clinical Trial Remote Collaboration

ResearchPrincipal Investigator · Awarded by Heart Imaging Technologies, LLC · 2017 - 2019

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Education, Training & Certifications


University of Vienna (Austria) · 1997 M.D.