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Isaretta Lee Riley

Assistant Professor of Medicine
Medicine, Pulmonary, Allergy, and Critical Care Medicine
1821 Hillandale Rd, #25-A, Box 31394, Durham, NC 27710

Selected Publications


Improving racial disparities in unmet palliative care needs among intensive care unit family members with a needs-targeted app intervention: The ICUconnect randomized clinical trial.

Journal Article Contemp Clin Trials · April 2021 INTRODUCTION: The technologies used to treat the millions who receive care in intensive care unit (ICUs) each year have steadily advanced. However, the quality of ICU-based communication has remained suboptimal, particularly concerning for Black patients a ... Full text Link to item Cite

A randomized, open-label, pragmatic study to assess reliever-triggered inhaled corticosteroid in African American/Black and Hispanic/Latinx adults with asthma: Design and methods of the PREPARE trial.

Journal Article Contemporary clinical trials · February 2021 BackgroundAsthma prevalence, morbidity, and mortality disproportionately impact African American/Black (AA/B) and Hispanic/Latinx (H/L) communities. Adherence to daily inhaled corticosteroid (ICS), recommended by asthma guidelines in all but the m ... Full text Cite

A Scoping Review of International Barriers to Asthma Medication Adherence Mapped to the Theoretical Domains Framework.

Journal Article J Allergy Clin Immunol Pract · January 2021 BACKGROUND: Internationally, adult asthma medication adherence rates are low. Studies characterizing variations in barriers by country are lacking. OBJECTIVE: To conduct a scoping review to characterize international variations in barriers to asthma medica ... Full text Link to item Cite

A Seat at the Table: Strategic Engagement in Service Activities for Early-Career Faculty From Underrepresented Groups in the Academy.

Journal Article Acad Med · August 2019 Many academic institutions strive to promote more diverse and inclusive campuses for faculty, staff, and students. As part of this effort, these institutions seek to include individuals from historically underrepresented groups (URGs)-such as women, people ... Full text Link to item Cite

A Systematic Review of Patient- and Family-Level Inhaled Corticosteroid Adherence Interventions in Black/African Americans.

Journal Article J Allergy Clin Immunol Pract · April 2019 BACKGROUND: Inhaled corticosteroid (ICS) adherence rates are suboptimal among adult black/African Americans. Comprehensive studies characterizing the effectiveness and the methodological approaches to the development of interventions to improve ICS adheren ... Full text Link to item Cite

AdheRence to Inhaled Corticosteroids in Asthma (ARICA): Intervention Development

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2019 Link to item Cite

Assessing heterogeneity of treatment effect analyses in health-related cluster randomized trials: A systematic review.

Journal Article PLoS One · 2019 BACKGROUND: Cluster-randomized trials (CRTs) are being increasingly used to test a range of interventions, including medical interventions commonly used in clinical practice. Policies created by the NIH and the Food and Drug Administration (FDA) require th ... Full text Link to item Cite

Factors associated with reporting results for pulmonary clinical trials in ClinicalTrials.gov.

Journal Article Clin Trials · February 2018 Background/aims The Food and Drug Administration Amendments Act mandates that applicable clinical trials report basic summary results to the ClinicalTrials.gov database within 1 year of trial completion or termination. We aimed to determine the proportion ... Full text Link to item Cite

Development and validation of an electronic medical record (EMR)-based computed phenotype of HIV-1 infection.

Journal Article J Am Med Inform Assoc · February 1, 2018 BACKGROUND: Electronic medical record (EMR) computed algorithms allow investigators to screen thousands of patient records to identify specific disease cases. No computed algorithms have been developed to detect all cases of human immunodeficiency virus (H ... Full text Link to item Cite

Assessing electronic health record phenotypes against gold-standard diagnostic criteria for diabetes mellitus.

Journal Article J Am Med Inform Assoc · April 1, 2017 OBJECTIVE: We assessed the sensitivity and specificity of 8 electronic health record (EHR)-based phenotypes for diabetes mellitus against gold-standard American Diabetes Association (ADA) diagnostic criteria via chart review by clinical experts. MATERIALS ... Full text Link to item Cite

Defining and targeting health disparities in chronic obstructive pulmonary disease.

Journal Article Int J Chron Obstruct Pulmon Dis · 2016 The global burden of chronic obstructive pulmonary disease (COPD) continues to grow in part due to better outcomes in other major diseases and in part because a substantial portion of the worldwide population continues to be exposed to inhalant toxins. How ... Full text Link to item Cite

Clinical Significance Of Isolated Increase In Residual Volume In Pulmonary Function Tests

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2013 Link to item Cite