Overview
Dr. Browndyke is an Associate Professor of Behavioral Health & Neurosciences in the Department of Psychiatry & Behavioral Sciences. He has a secondary appointment as Assistant Professor of Cardiovascular & Thoracic Surgery.
Dr. Browndyke's research interests involve the use of advanced neurocognitive and neuroimaging techniques for perioperative contributions to delirium and later dementia risk, monitoring of late-life neuropathological disease progression, and intervention/treatment outcomes. His research also involves novel telehealth methods for remote neurocognitive evaluation and implementation of non-invasive neuromodulatory techniques to assist in postoperative recovery and dementia risk reduction.
Dr. Browndyke's clinical expertise is focused upon geriatric neuropsychology with an emphasis in the assessment, diagnosis, and treatment of dementia and related disorders in adults and US veteran patient populations.
Dr. Browndyke's research interests involve the use of advanced neurocognitive and neuroimaging techniques for perioperative contributions to delirium and later dementia risk, monitoring of late-life neuropathological disease progression, and intervention/treatment outcomes. His research also involves novel telehealth methods for remote neurocognitive evaluation and implementation of non-invasive neuromodulatory techniques to assist in postoperative recovery and dementia risk reduction.
Dr. Browndyke's clinical expertise is focused upon geriatric neuropsychology with an emphasis in the assessment, diagnosis, and treatment of dementia and related disorders in adults and US veteran patient populations.
Current Duke Appointments & Affiliations
Associate Professor of Psychiatry and Behavioral Sciences
·
2026 - Present
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences,
Psychiatry & Behavioral Sciences
Assistant Professor in Surgery
·
2020 - Present
Surgery, Cardiovascular and Thoracic Surgery,
Surgery
Affiliate of the Center for Brain Imaging and Analysis
·
2007 - Present
Duke-UNC Brain Imaging and Analysis Center,
Institutes and Centers
Faculty Network Member of the Duke Institute for Brain Sciences
·
2008 - Present
Duke Institute for Brain Sciences,
University Institutes and Centers
Senior Fellow of the Center for the Study of Aging and Human Development
·
2020 - Present
Center for the Study of Aging and Human Development,
Institutes and Centers
Recent News Items
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Recent Scholarly Works
Differential Associations of Postoperative Plasma and Cerebrospinal Fluid Albumin Changes with Delirium Following Non-Cardiac Surgery.
Journal article medRxiv · September 21, 2026 BACKGROUND: Postoperative increases in cerebrospinal fluid (CSF) to plasma albumin ratio (CPAR), a blood-brain barrier dysfunction marker, have been associated with postoperative delirium (POD) and prolonged hospital stay. However, the contributions of pla ... Full text Link to item CitePreoperative Moderate-Severe Excessive Daytime Sleepiness Is Associated With Postoperative Cognitive Dysfunction in Older Surgical Patients.
Journal article J Am Geriatr Soc · August 30, 2026 BACKGROUND: Excessive daytime sleepiness may reflect increased vulnerability to postoperative neurocognitive disorders given its association with neurodegenerative disease, cognitive decline, and dementia. However, the role of excessive daytime sleepiness ... Full text Link to item CiteNeuroinflammation-associated thalamocortical functional connectivity and cognition in older adults.
Journal article J Neuroinflammation · August 1, 2026 Neuroinflammation has detrimental neurocognitive effects in patients with systemic and neuropsychiatric diseases. Yet, outside of these conditions, it is unclear to what extent neuroinflammation modulates brain network-level function in older adults in the ... Full text Link to item CiteRecent Grants
Neural Mechanisms Underlying Attentional Resilience in the Aging Brain
ResearchCo Investigator · Awarded by National Institute on Aging · 2024 - 2029Neurocognition & Greater Maintenance of Sinus Rhythm in AF (NOGGIN AF)
Clinical TrialCo Investigator · Awarded by National Institute on Aging · 2021 - 2027Low Neurophysiologic Resistance to Anesthetics as a Marker of Preclinical/Prodromal Alzheimer's Disease and Neurovascular Pathology, Delirium risk and Inattention
ResearchCo Investigator · Awarded by National Institute on Aging · 2022 - 2027View All Grants
Education
Louisiana State University, Baton Rouge ·
2001
Ph.D.