Overview
Dr. Browndyke is an Associate Professor of Behavioral Health & Neurosciences in the Department of Psychiatry & Behavioral Sciences. He has a secondary appointment as Assistant Professor of Cardiovascular & Thoracic Surgery.
Dr. Browndyke's research interests involve the use of advanced neurocognitive and neuroimaging techniques for perioperative contributions to delirium and later dementia risk, monitoring of late-life neuropathological disease progression, and intervention/treatment outcomes. His research also involves novel telehealth methods for remote neurocognitive evaluation and implementation of non-invasive neuromodulatory techniques to assist in postoperative recovery and dementia risk reduction.
Dr. Browndyke's clinical expertise is focused upon geriatric neuropsychology with an emphasis in the assessment, diagnosis, and treatment of dementia and related disorders in adults and US veteran patient populations.
Dr. Browndyke's research interests involve the use of advanced neurocognitive and neuroimaging techniques for perioperative contributions to delirium and later dementia risk, monitoring of late-life neuropathological disease progression, and intervention/treatment outcomes. His research also involves novel telehealth methods for remote neurocognitive evaluation and implementation of non-invasive neuromodulatory techniques to assist in postoperative recovery and dementia risk reduction.
Dr. Browndyke's clinical expertise is focused upon geriatric neuropsychology with an emphasis in the assessment, diagnosis, and treatment of dementia and related disorders in adults and US veteran patient populations.
Current Appointments & Affiliations
Associate Professor of Psychiatry and Behavioral Sciences
·
2021 - Present
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences,
Psychiatry & Behavioral Sciences
Assistant Professor in Surgery
·
2020 - Present
Surgery, Cardiovascular and Thoracic Surgery,
Surgery
Affiliate of the Center for Brain Imaging and Analysis
·
2007 - Present
Duke-UNC Brain Imaging and Analysis Center,
Institutes and Centers
Faculty Network Member of the Duke Institute for Brain Sciences
·
2008 - Present
Duke Institute for Brain Sciences,
University Institutes and Centers
Senior Fellow of the Center for the Study of Aging and Human Development
·
2020 - Present
Center for the Study of Aging and Human Development,
Institutes and Centers
Recent Publications
Associations between anaesthetic dose-adjusted intraoperative EEG alpha power, processing speed, and postoperative delirium: analysis of data from three prospective studies.
Journal Article Br J Anaesth · April 10, 2025 BACKGROUND: We previously have shown that low intraoperative EEG alpha power is associated with impaired preoperative cognition, a delirium risk factor, and that intraoperative anaesthetic-dose-adjusted EEG bispectral index values were associated with a fo ... Full text Link to item CiteMapping the impact of age and APOE risk factors for late onset Alzheimer's disease on long range brain connections through multiscale bundle analysis.
Journal Article Brain Struct Funct · March 19, 2025 Alzheimer's disease currently has no cure and is usually detected too late for interventions to be effective. In this study we have focused on cognitively normal subjects to study the impact of risk factors on their long-range brain connections. To detect ... Full text Link to item CiteNeurocognitive Dysfunction After Short (<20 Minutes) Duration Hypothermic Circulatory Arrest.
Journal Article Ann Thorac Surg · February 2025 BACKGROUND: It has long been held that the safe duration of hypothermic circulatory arrest (HCA) is at least 25 to 30 minutes. However, this belief is based primarily on clinical outcomes research and has not been systematically investigated using more sen ... Full text Link to item CiteRecent Grants
Neural Mechanisms Underlying Attentional Resilience in the Aging Brain
ResearchCo Investigator · Awarded by National Institute on Aging · 2024 - 2029Adaptive Neuromodulation of Working Memory Networks in Aging and Dementia
ResearchCo Investigator · Awarded by National Institute on Aging · 2022 - 2027Low Neurophysiologic Resistance to Anesthetics as a Marker of Preclinical/Prodromal Alzheimer's Disease and Neurovascular Pathology, Delirium risk and Inattention
ResearchCo Investigator · Awarded by National Institute on Aging · 2022 - 2027View All Grants
Education, Training & Certifications
Louisiana State University, Baton Rouge ·
2001
Ph.D.