Skip to main content

James R. Bain

Professor in Medicine
Medicine, Endocrinology, Metabolism, and Nutrition
Duke Box 104775, Durham, NC 27710
300 North Duke Street, Room 48-201, Duke Molecular Physiology Institute, Durham, NC 27701-2047

Current Appointments & Affiliations


Professor in Medicine · 2021 - Present Medicine, Endocrinology, Metabolism, and Nutrition, Medicine
Member of Sarah W. Stedman Nutrition and Metabolism Center · 2002 - Present Sarah Stedman Nutrition & Metabolism Center, Duke Molecular Physiology Institute
Senior Fellow in the Center for the Study of Aging · 2013 - Present Center for the Study of Aging and Human Development, Institutes and Centers

Recent Publications


Early Markers of Cardiac and Skeletal Muscle Metabolic Derangement in the Apc(min/+) Male Mouse.

Journal Article Cancer Rep (Hoboken) · September 2025 BACKGROUND AND AIMS: Cancer cachexia is a metabolic and wasting disease that occurs in up to 80% of cancer patients. Currently, there are no clear diagnostic criteria, its effects are irreversible, and it cannot be treated. Most patients progress undetecte ... Full text Link to item Cite

Soil and pasture health underlie improved beef nutrient density determined by untargeted metabolomics in Southern US grass finished beef systems.

Journal Article NPJ Sci Food · July 24, 2025 As concerns regarding beef production on human and environmental health increase, interest in sustainable practices has grown. This study compared soil, plant, and meat samples from three Southern US grass-fed beef systems to a paired grain-fed beef system ... Full text Link to item Cite
View All Publications

Recent Grants


Fibro/Adipogenic Progenitor Metabolic Reprogramming for Age-Related Muscle Fibrosis

ResearchCo-Mentor · Awarded by National Institute on Aging · 2024 - 2029

Elucidating racial and ethnic differences in functional effects of the vaginal microbiome in ovarian cancer

ResearchAdvisor · Awarded by National Cancer Institute · 2024 - 2027

Biomarkers of Dietary Intake and Exposure Data Coordinating Center

ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 2026

View All Grants

Education, Training & Certifications


University of Washington · 2001 Ph.D.