Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., University of Washington 2001
• 

  Previous Appointments & Affiliations

  • Professor in Medicine, Medicine, Endocrinology, Metabolism, and Nutrition, Medicine 2020
  • Associate Professor in Medicine, Medicine, Endocrinology, Metabolism, and Nutrition, Medicine 2015 - 2020
  • Assistant Professor in Medicine, Medicine, Endocrinology, Metabolism, and Nutrition, Medicine 2010 - 2015
• Research
• 

  Selected Grants

  • Biomarkers of Dietary Intake and Exposure Data Coordinating Center awarded by National Institutes of Health 2021 - 2026
  • Duke Women's Reproductive Health Research Scholars awarded by National Institutes of Health 2020 - 2025
  • Predicting Newborn and Childhood Adiposity: An Integrated Omics Approach awarded by Northwestern University 2018 - 2023
  • Serotonin as a Novel Biomarker for Progression to Type 2 Diabetes in Obese Adolescents awarded by National Institutes of Health 2018 - 2023
  • Metabolomic & Radiographic Markers of Fracture Risk Among Older Adults with Diabetes (K23) awarded by National Institutes of Health 2018 - 2023
  • Home Transplant to Preserve the Microbiota and Decrease GVHD awarded by  American Society of Hematology 2019 - 2022
  • Metagenomic Studies of the Gut Microbiomes of Obese and Lean Twins awarded by Washington University in St. Louis 2014 - 2021
  • AZD9668 and Neutrophil Elastase Inhibition to Prevent Graft-versus-Host Disease awarded by National Institutes of Health 2018 - 2019
  • Growth Failure in Extremely Preterm Infants: Microbiomic and Metabolomic Analysis awarded by Gerber Foundation 2014 - 2018
  • Maternal Obesity and Gestational Diabetes: Impact on the Metabolome awarded by Northwestern University 2014 - 2018
  • Metabolomics of low-trauma fracture among older women with diabetes awarded by National Institutes of Health 2014 - 2017
  • Metabolic Regulators of Insulin Secretion and Insulin Resistance awarded by National Institutes of Health 2013 - 2015
  • Integration of Oncogenic Networks in Cancer Phenotypes awarded by National Institutes of Health 2004 - 2011
  • missing activity
• 

  External Relationships

  • Agilent Technologies Inc.
  • National Medical Research Council, Singapore
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Lee, Richard H., James Bain, Michael Muehlbauer, Olga Ilkayeva, Carl Pieper, Doug Wixted, and Cathleen Colón-Emeric. “Metabolic factors associated with incident fracture among older adults with type 2 diabetes mellitus: a nested case-control study.” Osteoporos Int, April 26, 2023. https://doi.org/10.1007/s00198-023-06763-1.
       Full Text  Link to Item
    • Gleason, Brooke, Alan Kuang, James R. Bain, Michael J. Muehlbauer, Olga R. Ilkayeva, Denise M. Scholtens, and William L. Lowe. “Association of Maternal Metabolites and Metabolite Networks with Newborn Outcomes in a Multi-Ancestry Cohort.” Metabolites 13, no. 4 (March 31, 2023). https://doi.org/10.3390/metabo13040505.
       Full Text  Link to Item
    • Leibold, Noah, James R. Bain, and Florin Despa. “Type-2 Diabetes, Pancreatic Amylin, and Neuronal Metabolic Remodeling in Alzheimer's Disease.” Mol Nutr Food Res, January 28, 2023, e2200405. https://doi.org/10.1002/mnfr.202200405.
       Full Text  Open Access Copy  Link to Item
    • Gumus Balikcioglu, Pinar, Catherine Jachthuber Trub, Metin Balikcioglu, Olga Ilkayeva, Phillip J. White, Michael Muehlbauer, James R. Bain, Sarah Armstrong, and Michael Freemark. “Branched-chain α-keto acids and glutamate/glutamine: Biomarkers of insulin resistance in childhood obesity.” Endocrinology, Diabetes & Metabolism 6, no. 1 (January 2023): e388. https://doi.org/10.1002/edm2.388.
       Full Text
    • Parker, Daniel C., William E. Kraus, Heather E. Whitson, Virginia B. Kraus, Patrick J. Smith, Harvey Jay Cohen, Carl F. Pieper, et al. “Tryptophan Metabolism and Neurodegeneration: Longitudinal Associations of Kynurenine Pathway Metabolites with Cognitive Performance and Plasma Alzheimer's Disease and Related Dementias Biomarkers in the Duke Physical Performance Across the LifeSpan Study.” J Alzheimers Dis 91, no. 3 (2023): 1141–50. https://doi.org/10.3233/JAD-220906.
       Full Text  Open Access Copy  Link to Item
    • Giessner, Stephanie, Megan E. Ramaker, Kathryn Blew, Matthew L. Crawford, Russell P. Grant, James R. Bain, Michael Muehlbauer, et al. “Disrupted Circadian Rhythm of Epinephrine in Males With Youth-Onset Type 2 Diabetes.” J Endocr Soc 7, no. 2 (December 15, 2022): bvac190. https://doi.org/10.1210/jendso/bvac190.
       Full Text  Link to Item
    • Gill, Nathan P., Raji Balasubramanian, James R. Bain, Michael J. Muehlbauer, William L. Lowe, and Denise M. Scholtens. “Correction: Path-level interpretation of Gaussian graphical models using the pair-path subscore.” Bmc Bioinformatics 23, no. 1 (November 4, 2022): 462. https://doi.org/10.1186/s12859-022-04990-7.
       Full Text  Link to Item
    • Letourneau, Jeffrey, Zachary C. Holmes, Eric P. Dallow, Heather K. Durand, Sharon Jiang, Verónica M. Carrion, Savita K. Gupta, et al. “Ecological memory of prior nutrient exposure in the human gut microbiome.” Isme J 16, no. 11 (November 2022): 2479–90. https://doi.org/10.1038/s41396-022-01292-x.
       Full Text  Open Access Copy  Link to Item
    • Eckhoff, Austin M., Ashton A. Connor, Julie K. M. Thacker, Dan G. Blazer, Harvey G. Moore, Randall P. Scheri, Sandhya A. Lagoo-Deenadayalan, et al. “A Multidimensional Bioinformatic Platform for the Study of Human Response to Surgery.” Ann Surg 275, no. 6 (June 1, 2022): 1094–1102. https://doi.org/10.1097/SLA.0000000000005429.
       Full Text  Link to Item
    • Gill, Nathan P., Raji Balasubramanian, James R. Bain, Michael J. Muehlbauer, William L. Lowe, and Denise M. Scholtens. “Path-level interpretation of Gaussian graphical models using the pair-path subscore.” Bmc Bioinformatics 23, no. 1 (January 5, 2022): 12. https://doi.org/10.1186/s12859-021-04542-5.
       Full Text  Link to Item
    • Siamakpour-Reihani, Sharareh, Felicia Cao, Jing Lyu, Yi Ren, Andrew B. Nixon, Jichun Xie, Amy T. Bush, et al. “Evaluating immune response and metabolic related biomarkers pre-allogenic hematopoietic stem cell transplant in acute myeloid leukemia.” Plos One 17, no. 6 (2022): e0268963. https://doi.org/10.1371/journal.pone.0268963.
       Full Text  Link to Item
    • Vliet, S. van, J. Bain, D. Hill, M. Muehlbauer, C. Pieper, K. Huffman, F. D. Provenza, S. Kronberg, S. Baumann, and T. Anumol. “Comparing the Chemical Profiles of Plant-Based and Traditional Meats Using GC–MS-Based Metabolomics.” Lc Gc North America 40, no. 12 (January 1, 2022): 573–78. https://doi.org/10.56530/lcgc.na.qf2278a1.
       Full Text
    • Lunyera, Joseph, Clarissa J. Diamantidis, Hayden B. Bosworth, Uptal D. Patel, James Bain, Michael J. Muehlbauer, Olga Ilkayeva, et al. “Urine tricarboxylic acid cycle signatures of early-stage diabetic kidney disease.” Metabolomics 18, no. 1 (December 20, 2021): 5. https://doi.org/10.1007/s11306-021-01858-4.
       Full Text  Link to Item
    • Liu, Yu, Alan Kuang, James R. Bain, Michael J. Muehlbauer, Olga R. Ilkayeva, Lynn P. Lowe, Boyd E. Metzger, Christopher B. Newgard, Denise M. Scholtens, and William L. Lowe. “Maternal Metabolites Associated With Gestational Diabetes Mellitus and a Postpartum Disorder of Glucose Metabolism.” J Clin Endocrinol Metab 106, no. 11 (October 21, 2021): 3283–94. https://doi.org/10.1210/clinem/dgab513.
       Full Text  Link to Item
    • White, Phillip J., Robert W. McGarrah, Mark A. Herman, James R. Bain, Svati H. Shah, and Christopher B. Newgard. “Insulin action, type 2 diabetes, and branched-chain amino acids: A two-way street.” Molecular Metabolism 52 (October 2021): 101261. https://doi.org/10.1016/j.molmet.2021.101261.
       Full Text
    • Truby, Lauren K., Jessica A. Regan, Stephanie N. Giamberardino, Olga Ilkayeva, James Bain, Christopher B. Newgard, Christopher M. O’Connor, et al. “Circulating long chain acylcarnitines and outcomes in diabetic heart failure: an HF-ACTION clinical trial substudy.” Cardiovasc Diabetol 20, no. 1 (August 3, 2021): 161. https://doi.org/10.1186/s12933-021-01353-z.
       Full Text  Link to Item
    • Vliet, Stephan van, James R. Bain, Michael J. Muehlbauer, Frederick D. Provenza, Scott L. Kronberg, Carl F. Pieper, and Kim M. Huffman. “A metabolomics comparison of plant-based meat and grass-fed meat indicates large nutritional differences despite comparable Nutrition Facts panels.” Sci Rep 11, no. 1 (July 5, 2021): 13828. https://doi.org/10.1038/s41598-021-93100-3.
       Full Text  Open Access Copy  Link to Item
    • Jachthuber Trub, Catherine, Metin Balikcioglu, Michael Freemark, James Bain, Michael Muehlbauer, Olga Ilkayeva, Phillip J. White, et al. “Impact of lifestyle Intervention on branched-chain amino acid catabolism and insulin sensitivity in adolescents with obesity.” Endocrinol Diabetes Metab 4, no. 3 (July 2021): e00250. https://doi.org/10.1002/edm2.250.
       Full Text  Link to Item
    • Tyson, Crystal C., Alison Luciano, Jennifer L. Modliszewski, David L. Corcoran, James R. Bain, Michael Muehlbauer, Olga Ilkayeva, et al. “Effect of Bicarbonate on Net Acid Excretion, Blood Pressure, and Metabolism in Patients With and Without CKD: The Acid Base Compensation in CKD Study.” Am J Kidney Dis 78, no. 1 (July 2021): 38–47. https://doi.org/10.1053/j.ajkd.2020.10.015.
       Full Text  Link to Item
    • Pourafshar, Shirin, Mira Nicchitta, Crystal C. Tyson, Laura P. Svetkey, David L. Corcoran, James R. Bain, Michael J. Muehlbauer, et al. “Urine and Plasma Metabolome of Healthy Adults Consuming the DASH (Dietary Approaches to Stop Hypertension) Diet: A Randomized Pilot Feeding Study.” Nutrients 13, no. 6 (May 22, 2021). https://doi.org/10.3390/nu13061768.
       Full Text  Link to Item
    • Alcazar, Oscar, Luis F. Hernandez, Ernesto S. Nakayasu, Carrie D. Nicora, Charles Ansong, Michael J. Muehlbauer, James R. Bain, et al. “Parallel Multi-Omics in High-Risk Subjects for the Identification of Integrated Biomarker Signatures of Type 1 Diabetes.” Biomolecules 11, no. 3 (March 2021): 383. https://doi.org/10.3390/biom11030383.
       Full Text
    • Enriquez-Hesles, Elisa, Daniel L. Smith, Nazif Maqani, Margaret B. Wierman, Matthew D. Sutcliffe, Ryan D. Fine, Agata Kalita, et al. “A cell-nonautonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism.” J Biol Chem 296 (2021): 100125. https://doi.org/10.1074/jbc.RA120.015402.
       Full Text  Link to Item
    • Ramalingam, Sendhilnathan, Sharareh Siamakpour-Reihani, Lauren Bohannan, Yi Ren, Alexander Sibley, Jeff Sheng, Li Ma, et al. “A phase 2 trial of the somatostatin analog pasireotide to prevent GI toxicity and acute GVHD in allogeneic hematopoietic stem cell transplant.” Plos One 16, no. 6 (January 2021): e0252995. https://doi.org/10.1371/journal.pone.0252995.
       Full Text
    • Ellison, Stephen, Jawan W. Abdulrahim, Lydia Coulter Kwee, Nathan A. Bihlmeyer, Neha Pagidipati, Robert McGarrah, James R. Bain, William E. Kraus, and Svati H. Shah. “Novel plasma biomarkers improve discrimination of metabolic health independent of weight.” Sci Rep 10, no. 1 (December 7, 2020): 21365. https://doi.org/10.1038/s41598-020-78478-w.
       Full Text  Link to Item
    • Enriquez-Hesles, Elisa, Daniel L. Smith, Nazif Maqani, Margaret B. Wierman, Matthew D. Sutcliffe, Ryan D. Fine, Agata Kalita, et al. “A cell-nonautonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism.” J Biol Chem 296 (December 2, 2020): 100125. https://doi.org/10.1074/jbc.RA120.015402.
       Full Text  Link to Item
    • White, Phillip J., Amanda L. Lapworth, Robert W. McGarrah, Lydia Coulter Kwee, Scott B. Crown, Olga Ilkayeva, Jie An, et al. “Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine Depletion.” Cell Rep 33, no. 6 (November 10, 2020): 108375. https://doi.org/10.1016/j.celrep.2020.108375.
       Full Text  Link to Item
    • Parker, Daniel C., Cathleen Colόn-Emeric, Janet L. Huebner, Ching-Heng Chou, Virginia Byers Kraus, Carl F. Pieper, Richard Sloane, et al. “Biomarkers Associated with Physical Resilience After Hip Fracture.” J Gerontol a Biol Sci Med Sci 75, no. 10 (September 25, 2020): e166–72. https://doi.org/10.1093/gerona/glaa119.
       Full Text  Link to Item
    • Liu, Yu, Alan Kuang, Octavious Talbot, James R. Bain, Michael J. Muehlbauer, M Geoffrey Hayes, Olga R. Ilkayeva, et al. “Metabolomic and genetic associations with insulin resistance in pregnancy.” Diabetologia 63, no. 9 (September 2020): 1783–95. https://doi.org/10.1007/s00125-020-05198-1.
       Full Text  Link to Item
    • Clinton, Chelsea M., James R. Bain, Michael J. Muehlbauer, YuanYuan Li, Leping Li, Sara K. O’Neal, Brenna L. Hughes, David E. Cantonwine, Thomas F. Mcelrath, and Kelly K. Ferguson. “Non-targeted urinary metabolomics in pregnancy and associations with fetal growth restriction.” Sci Rep 10, no. 1 (March 24, 2020): 5307. https://doi.org/10.1038/s41598-020-62131-7.
       Full Text  Link to Item
    • Kadakia, Rachel, Octavious Talbot, Alan Kuang, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, Olga R. Ilkayeva, et al. “Cord Blood Metabolomics: Association With Newborn Anthropometrics and C-Peptide Across Ancestries.” J Clin Endocrinol Metab 104, no. 10 (October 1, 2019): 4459–72. https://doi.org/10.1210/jc.2019-00238.
       Full Text  Link to Item
    • Alcazar, Oscar, Luis F. Hernandez, Ashley Tschiggfrie, Michael J. Muehlbauer, James R. Bain, Peter Buchwald, and Midhat H. Abdulreda. “Feasibility of Localized Metabolomics in the Study of Pancreatic Islets and Diabetes.” Metabolites 9, no. 10 (September 29, 2019). https://doi.org/10.3390/metabo9100207.
       Full Text  Link to Item
    • Ilaiwy, Amro, Gabriella A. M. Ten Have, James R. Bain, Michael J. Muehlbauer, Sara K. O’Neal, Jessica M. Berthiaume, Traci L. Parry, Nicolaas E. Deutz, and Monte S. Willis. “Identification of Metabolic Changes in Ileum, Jejunum, Skeletal Muscle, Liver, and Lung in a Continuous I.V. Pseudomonas aeruginosa Model of Sepsis Using Nontargeted Metabolomics Analysis.” Am J Pathol 189, no. 9 (September 2019): 1797–1813. https://doi.org/10.1016/j.ajpath.2019.05.021.
       Full Text  Link to Item
    • Younge, Noelle E., Christopher B. Newgard, C Michael Cotten, Ronald N. Goldberg, Michael J. Muehlbauer, James R. Bain, Robert D. Stevens, et al. “Disrupted Maturation of the Microbiota and Metabolome among Extremely Preterm Infants with Postnatal Growth Failure.” Sci Rep 9, no. 1 (June 3, 2019): 8167. https://doi.org/10.1038/s41598-019-44547-y.
       Full Text  Link to Item
    • Kadakia, Rachel, Michael Nodzenski, Octavious Talbot, Alan Kuang, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, et al. “Maternal metabolites during pregnancy are associated with newborn outcomes and hyperinsulinaemia across ancestries.” Diabetologia 62, no. 3 (March 2019): 473–84. https://doi.org/10.1007/s00125-018-4781-1.
       Full Text  Link to Item
    • Parker, Daniel, Richard Sloane, Carl F. Pieper, Katherine S. Hall, Virginia B. Kraus, William E. Kraus, Janet L. Huebner, et al. “Age-Related Adverse Inflammatory and Metabolic Changes Begin Early in Adulthood.” J Gerontol a Biol Sci Med Sci 74, no. 3 (February 15, 2019): 283–89. https://doi.org/10.1093/gerona/gly121.
       Full Text  Open Access Copy  Link to Item
    • Ravi, Saranya, Traci L. Parry, Monte S. Willis, Pamela Lockyer, Cam Patterson, James R. Bain, Robert D. Stevens, Olga R. Ilkayeva, Christopher B. Newgard, and Jonathan C. Schisler. “Adverse Effects of Fenofibrate in Mice Deficient in the Protein Quality Control Regulator, CHIP.” J Cardiovasc Dev Dis 5, no. 3 (August 15, 2018). https://doi.org/10.3390/jcdd5030043.
       Full Text  Link to Item
    • Scialla, Julia J., Landon Brown, Susan Gurley, David L. Corcoran, James R. Bain, Michael J. Muehlbauer, Sara K. O’Neal, et al. “Metabolic Changes with Base-Loading in CKD.” Clin J Am Soc Nephrol 13, no. 8 (August 7, 2018): 1244–46. https://doi.org/10.2215/CJN.01830218.
       Full Text  Open Access Copy  Link to Item
    • Shantavasinkul, Prapimporn Chattranukulchai, Michael J. Muehlbauer, James R. Bain, Olga R. Ilkayeva, Damian M. Craig, Christopher B. Newgard, Laura P. Svetkey, Svati H. Shah, and Alfonso Torquati. “Improvement in insulin resistance after gastric bypass surgery is correlated with a decline in plasma 2-hydroxybutyric acid.” Surg Obes Relat Dis 14, no. 8 (August 2018): 1126–32. https://doi.org/10.1016/j.soard.2018.03.033.
       Full Text  Link to Item
    • Bhupathiraju, Shilpa N., Marta Guasch-Ferré, Meghana D. Gadgil, Christopher B. Newgard, James R. Bain, Michael J. Muehlbauer, Olga R. Ilkayeva, et al. “Dietary Patterns among Asian Indians Living in the United States Have Distinct Metabolomic Profiles That Are Associated with Cardiometabolic Risk.” J Nutr 148, no. 7 (July 1, 2018): 1150–59. https://doi.org/10.1093/jn/nxy074.
       Full Text  Open Access Copy  Link to Item
    • Zuo, Xintong, Alison Luciano, Carl F. Pieper, James R. Bain, Virginia B. Kraus, William E. Kraus, Miriam C. Morey, and Harvey J. Cohen. “Combined Inflammation and Metabolism Biomarker Indices of Robust and Impaired Physical Function in Older Adults.” J Am Geriatr Soc 66, no. 7 (July 2018): 1353–59. https://doi.org/10.1111/jgs.15393.
       Full Text  Open Access Copy  Link to Item
    • An, Jie, Liping Wang, Michael L. Patnode, Vanessa K. Ridaura, Jonathan M. Haldeman, Robert D. Stevens, Olga Ilkayeva, et al. “Physiological mechanisms of sustained fumagillin-induced weight loss.” Jci Insight 3, no. 5 (March 8, 2018). https://doi.org/10.1172/jci.insight.99453.
       Full Text  Link to Item
    • Abaffy, Tatjana, James R. Bain, Michael J. Muehlbauer, Ivan Spasojevic, Shweta Lodha, Elisa Bruguera, Sara K. O’Neal, So Young Kim, and Hiroaki Matsunami. “A Testosterone Metabolite 19-Hydroxyandrostenedione Induces Neuroendocrine Trans-Differentiation of Prostate Cancer Cells via an Ectopic Olfactory Receptor.” Front Oncol 8 (2018): 162. https://doi.org/10.3389/fonc.2018.00162.
       Full Text  Open Access Copy  Link to Item
    • Parry, Traci L., Joseph W. Starnes, Sara K. O’Neal, James R. Bain, Michael J. Muehlbauer, Aubree Honcoop, Amro Ilaiwy, Peter Christopher, Cam Patterson, and Monte S. Willis. “Untargeted metabolomics analysis of ischemia-reperfusion-injured hearts ex vivo from sedentary and exercise-trained rats.” Metabolomics 14, no. 1 (January 2018): 8. https://doi.org/10.1007/s11306-017-1303-y.
       Full Text  Link to Item
    • Jensen, Brian C., Traci L. Parry, Wei Huang, Ju Youn Beak, Amro Ilaiwy, James R. Bain, Christopher B. Newgard, et al. “Effects of the kinase inhibitor sorafenib on heart, muscle, liver and plasma metabolism in vivo using non-targeted metabolomics analysis.” Br J Pharmacol 174, no. 24 (December 2017): 4797–4811. https://doi.org/10.1111/bph.14062.
       Full Text  Link to Item
    • Wang, Hanghang, Michael J. Muehlbauer, Sara K. O’Neal, Christopher B. Newgard, Elizabeth R. Hauser, James R. Bain, and Svati H. Shah. “Recommendations for Improving Identification and Quantification in Non-Targeted, GC-MS-Based Metabolomic Profiling of Human Plasma.” Metabolites 7, no. 3 (August 25, 2017). https://doi.org/10.3390/metabo7030045.
       Full Text  Link to Item
    • Starnes, Joseph W., Traci L. Parry, Sara K. O’Neal, James R. Bain, Michael J. Muehlbauer, Aubree Honcoop, Amro Ilaiwy, Peter M. Christopher, Cam Patterson, and Monte S. Willis. “Exercise-Induced Alterations in Skeletal Muscle, Heart, Liver, and Serum Metabolome Identified by Non-Targeted Metabolomics Analysis.” Metabolites 7, no. 3 (August 8, 2017). https://doi.org/10.3390/metabo7030040.
       Full Text  Link to Item
    • Wang, Hanghang, Kevin Anstrom, Olga Ilkayeva, Michael J. Muehlbauer, James R. Bain, Steven McNulty, Christopher B. Newgard, et al. “Sildenafil Treatment in Heart Failure With Preserved Ejection Fraction: Targeted Metabolomic Profiling in the RELAX Trial.” Jama Cardiol 2, no. 8 (August 1, 2017): 896–901. https://doi.org/10.1001/jamacardio.2017.1239.
       Full Text  Link to Item
    • Abdullah, Muhammad, Joe N. Kornegay, Aubree Honcoop, Traci L. Parry, Cynthia J. Balog-Alvarez, Sara K. O’Neal, James R. Bain, et al. “Non-Targeted Metabolomics Analysis of Golden Retriever Muscular Dystrophy-Affected Muscles Reveals Alterations in Arginine and Proline Metabolism, and Elevations in Glutamic and Oleic Acid In Vivo.” Metabolites 7, no. 3 (July 29, 2017). https://doi.org/10.3390/metabo7030038.
       Full Text  Link to Item
    • Ilaiwy, Amro, Megan T. Quintana, James R. Bain, Michael J. Muehlbauer, David I. Brown, William E. Stansfield, and Monte S. Willis. “Erratum to 'Cessation of biomechanical stretch model of C2C12 cells modelsmyocyte atrophy and anaplerotic changes in metabolism usingnon-targeted metabolomics analysisAmro' [Int. J. Biochem. Cell Biol. (2016) 80-92].” Int J Biochem Cell Biol 88 (July 2017): 238–40. https://doi.org/10.1016/j.biocel.2017.02.010.
       Full Text  Link to Item
    • Jacob, Saya, Michael Nodzenski, Anna C. Reisetter, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, Olga R. Ilkayeva, et al. “Targeted Metabolomics Demonstrates Distinct and Overlapping Maternal Metabolites Associated With BMI, Glucose, and Insulin Sensitivity During Pregnancy Across Four Ancestry Groups.” Diabetes Care 40, no. 7 (July 2017): 911–19. https://doi.org/10.2337/dc16-2453.
       Full Text  Link to Item
    • Lowe, William L., James R. Bain, Michael Nodzenski, Anna C. Reisetter, Michael J. Muehlbauer, Robert D. Stevens, Olga R. Ilkayeva, et al. “Maternal BMI and Glycemia Impact the Fetal Metabolome.” Diabetes Care 40, no. 7 (July 2017): 902–10. https://doi.org/10.2337/dc16-2452.
       Full Text  Link to Item
    • Jensen, Brian C., Traci L. Parry, Wei Huang, Amro Ilaiwy, James R. Bain, Michael J. Muehlbauer, Sara K. O’Neal, Cam Patterson, Gary L. Johnson, and Monte S. Willis. “Non-Targeted Metabolomics Analysis of the Effects of Tyrosine Kinase Inhibitors Sunitinib and Erlotinib on Heart, Muscle, Liver and Serum Metabolism In Vivo.” Metabolites 7, no. 3 (June 22, 2017). https://doi.org/10.3390/metabo7030031.
       Full Text  Link to Item
    • Sandler, Victoria, Anna C. Reisetter, James R. Bain, Michael J. Muehlbauer, Michael Nodzenski, Robert D. Stevens, Olga Ilkayeva, et al. “Associations of maternal BMI and insulin resistance with the maternal metabolome and newborn outcomes.” Diabetologia 60, no. 3 (March 2017): 518–30. https://doi.org/10.1007/s00125-016-4182-2.
       Full Text  Link to Item
    • Reisetter, Anna C., Michael J. Muehlbauer, James R. Bain, Michael Nodzenski, Robert D. Stevens, Olga Ilkayeva, Boyd E. Metzger, Christopher B. Newgard, William L. Lowe, and Denise M. Scholtens. “Mixture model normalization for non-targeted gas chromatography/mass spectrometry metabolomics data.” Bmc Bioinformatics 18, no. 1 (February 2, 2017): 84. https://doi.org/10.1186/s12859-017-1501-7.
       Full Text  Link to Item
    • Kraus, William E., Carl F. Pieper, Kim M. Huffman, Dana K. Thompson, Virginia B. Kraus, Miriam C. Morey, Harvey J. Cohen, et al. “Association of Plasma Small-Molecule Intermediate Metabolites With Age and Body Mass Index Across Six Diverse Study Populations.” J Gerontol a Biol Sci Med Sci 71, no. 11 (November 2016): 1507–13. https://doi.org/10.1093/gerona/glw031.
       Full Text  Link to Item
    • Ilaiwy, Amro, Megan T. Quintana, James R. Bain, Michael J. Muehlbauer, David I. Brown, William E. Stansfield, and Monte S. Willis. “Cessation of biomechanical stretch model of C2C12 cells models myocyte atrophy and anaplerotic changes in metabolism using non-targeted metabolomics analysis.” Int J Biochem Cell Biol 79 (October 2016): 80–92. https://doi.org/10.1016/j.biocel.2016.08.012.
       Full Text  Link to Item
    • Files, D Clark, Amro Ilaiwy, Traci L. Parry, Kevin W. Gibbs, Chun Liu, James R. Bain, Osvaldo Delbono, Michael J. Muehlbauer, and Monte S. Willis. “Lung injury-induced skeletal muscle wasting in aged mice is linked to alterations in long chain fatty acid metabolism.” Metabolomics 12, no. 8 (August 2016). https://doi.org/10.1007/s11306-016-1079-5.
       Full Text  Link to Item
    • Quintana, Megan T., Traci L. Parry, Jun He, Cecelia C. Yates, Tatiana N. Sidorova, Katherine T. Murray, James R. Bain, et al. “Cardiomyocyte-Specific Human Bcl2-Associated Anthanogene 3 P209L Expression Induces Mitochondrial Fragmentation, Bcl2-Associated Anthanogene 3 Haploinsufficiency, and Activates p38 Signaling.” Am J Pathol 186, no. 8 (August 2016): 1989–2007. https://doi.org/10.1016/j.ajpath.2016.03.017.
       Full Text  Link to Item
    • Hunter, Wynn G., Jacob P. Kelly, Robert W. McGarrah, Michel G. Khouri, Damian Craig, Carol Haynes, Olga Ilkayeva, et al. “Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure.” J Am Heart Assoc 5, no. 8 (July 29, 2016). https://doi.org/10.1161/JAHA.115.003190.
       Full Text  Open Access Copy  Link to Item
    • Scholtens, Denise M., James R. Bain, Anna C. Reisetter, Michael J. Muehlbauer, Michael Nodzenski, Robert D. Stevens, Olga Ilkayeva, et al. “Metabolic Networks and Metabolites Underlie Associations Between Maternal Glucose During Pregnancy and Newborn Size at Birth.” Diabetes 65, no. 7 (July 2016): 2039–50. https://doi.org/10.2337/db15-1748.
       Full Text  Link to Item
    • White, Phillip J., Amanda L. Lapworth, Jie An, Liping Wang, Robert W. McGarrah, Robert D. Stevens, Olga Ilkayeva, et al. “Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export.” Mol Metab 5, no. 7 (July 2016): 538–51. https://doi.org/10.1016/j.molmet.2016.04.006.
       Full Text  Link to Item
    • Quinones, Quintin J., Zhiquan Zhang, Qing Ma, Michael P. Smith, Erik Soderblom, M Arthur Moseley, James Bain, et al. “Proteomic Profiling Reveals Adaptive Responses to Surgical Myocardial Ischemia-Reperfusion in Hibernating Arctic Ground Squirrels Compared to Rats.” Anesthesiology 124, no. 6 (June 2016): 1296–1310. https://doi.org/10.1097/ALN.0000000000001113.
       Full Text  Link to Item
    • Marcelo, Kathrina L., Thomas Ribar, Christopher R. Means, Anna Tsimelzon, Robert D. Stevens, Olga Ilkayeva, James R. Bain, et al. “Research Resource: Roles for Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) in Systems Metabolism.” Mol Endocrinol 30, no. 5 (May 2016): 557–72. https://doi.org/10.1210/me.2016-1021.
       Full Text  Link to Item
    • Ilaiwy, Amro, Miao Liu, Traci L. Parry, James R. Bain, Christopher B. Newgard, Jonathan C. Schisler, Michael J. Muehlbauer, Florin Despa, and Monte S. Willis. “Human amylin proteotoxicity impairs protein biosynthesis, and alters major cellular signaling pathways in the heart, brain and liver of humanized diabetic rat model in vivo.” Metabolomics 12, no. 5 (May 2016). https://doi.org/10.1007/s11306-016-1022-9.
       Full Text  Link to Item
    • Charbonneau, Mark R., David O’Donnell, Laura V. Blanton, Sarah M. Totten, Jasmine C. C. Davis, Michael J. Barratt, Jiye Cheng, et al. “Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition.” Cell 164, no. 5 (February 25, 2016): 859–71. https://doi.org/10.1016/j.cell.2016.01.024.
       Full Text  Link to Item
    • Irizarry, Krystal A., James Bain, Merlin G. Butler, Olga Ilkayeva, Michael Muehlbauer, Andrea M. Haqq, and Michael Freemark. “Metabolic profiling in Prader-Willi syndrome and nonsyndromic obesity: sex differences and the role of growth hormone.” Clin Endocrinol (Oxf) 83, no. 6 (December 2015): 797–805. https://doi.org/10.1111/cen.12766.
       Full Text  Open Access Copy  Link to Item
    • Kraus, William E., Deborah M. Muoio, Robert Stevens, Damian Craig, James R. Bain, Elizabeth Grass, Carol Haynes, et al. “Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis.” Plos Genet 11, no. 11 (November 2015): e1005553. https://doi.org/10.1371/journal.pgen.1005553.
       Full Text  Open Access Copy  Link to Item
    • Banerjee, Ranjan, Scott J. Bultman, Darcy Holley, Carolyn Hillhouse, James R. Bain, Christopher B. Newgard, Michael J. Muehlbauer, and Monte S. Willis. “Non-targeted metabolomics of Brg1/Brm double-mutant cardiomyocytes reveals a novel role for SWI/SNF complexes in metabolic homeostasis.” Metabolomics 11, no. 5 (October 1, 2015): 1287–1301. https://doi.org/10.1007/s11306-015-0786-7.
       Full Text  Link to Item
    • Glynn, Erin L., Lucy W. Piner, Kim M. Huffman, Cris A. Slentz, Lorraine Elliot-Penry, Hiba AbouAssi, Phillip J. White, et al. “Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans.” Diabetologia 58, no. 10 (October 2015): 2324–35. https://doi.org/10.1007/s00125-015-3705-6.
       Full Text  Link to Item
    • He, Jun, Megan T. Quintana, Jenyth Sullivan, Traci L Parry, Trisha J Grevengoed, Jonathan C. Schisler, Joseph A. Hill, et al. “MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet.” Cardiovasc Diabetol 14 (August 5, 2015): 97. https://doi.org/10.1186/s12933-015-0252-x.
       Full Text  Link to Item
    • Quintana, Megan T., Jun He, Jenyth Sullivan, Trisha Grevengoed, Jonathan Schisler, Yipin Han, Joseph A. Hill, et al. “Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet.” Bmc Endocr Disord 15 (July 28, 2015): 36. https://doi.org/10.1186/s12902-015-0028-z.
       Full Text  Link to Item
    • Banerjee, Ranjan, Jun He, Carolyn Spaniel, Megan T. Quintana, Zhongjing Wang, James Bain, Christopher B. Newgard, Michael J. Muehlbauer, and Monte S. Willis. “Non-targeted metabolomics analysis of cardiac Muscle Ring Finger-1 (MuRF1), MuRF2, and MuRF3 in vivo reveals novel and redundant metabolic changes.” Metabolomics 11, no. 2 (April 2015): 312–22. https://doi.org/10.1007/s11306-014-0695-1.
       Full Text  Link to Item
    • Newbern, D., P. Gumus Balikcioglu, M. Balikcioglu, J. Bain, M. Muehlbauer, R. Stevens, O. Ilkayeva, et al. “Erratum: Sex differences in biomarkers associated with insulin resistance in obese adolescents: Metabolomic profiling and principal components analysis (Journal of Clinical Endocrinology and Metabolism (2014) 99 (4730-4739) DOI: 10.1210/jc.2014-2080).” Journal of Clinical Endocrinology and Metabolism 100, no. 4 (April 1, 2015): 1709. https://doi.org/10.1210/jc.2015-1354.
       Full Text
    • Glass, O. K., B. A. Inman, G. Broadwater, K. S. Courneya, J. R. Mackey, S. Goruk, E. R. Nelson, et al. “Effect of aerobic training on the host systemic milieu in patients with solid tumours: an exploratory correlative study.” Br J Cancer 112, no. 5 (March 3, 2015): 825–31. https://doi.org/10.1038/bjc.2014.662.
       Full Text  Link to Item
    • Glass, O. K., B. A. Inman, G. Broadwater, K. S. Courneya, J. R. Mackey, S. Goruk, E. R. Nelson, et al. “Effect of aerobic training on the host systemic milieu in patients with solid tumours: An exploratory correlative study.” British Journal of Cancer 112, no. 5 (March 3, 2015): 825–31. https://doi.org/10.1038/bjc.2014.662.
       Full Text
    • Newbern, Dorothee, Pinar Gumus Balikcioglu, Metin Balikcioglu, James Bain, Michael Muehlbauer, Robert Stevens, Olga Ilkayeva, et al. “Sex differences in biomarkers associated with insulin resistance in obese adolescents: metabolomic profiling and principal components analysis.” J Clin Endocrinol Metab 99, no. 12 (December 2014): 4730–39. https://doi.org/10.1210/jc.2014-2080.
       Full Text  Link to Item
    • Nodzenski, Michael, Michael J. Muehlbauer, James R. Bain, Anna C. Reisetter, William L. Lowe, and Denise M. Scholtens. “Metabomxtr: an R package for mixture-model analysis of non-targeted metabolomics data.” Bioinformatics 30, no. 22 (November 15, 2014): 3287–88. https://doi.org/10.1093/bioinformatics/btu509.
       Full Text  Link to Item
    • Todor, Horia, Keely Dulmage, Nicholas Gillum, James R. Bain, Michael J. Muehlbauer, and Amy K. Schmid. “A transcription factor links growth rate and metabolism in the hypersaline adapted archaeon Halobacterium salinarum.” Mol Microbiol 93, no. 6 (September 2014): 1172–82. https://doi.org/10.1111/mmi.12726.
       Full Text  Link to Item
    • Tripathy, Sasmita, Kelli A. Lytle, Robert D. Stevens, James R. Bain, Christopher B. Newgard, Andrew S. Greenberg, Li-Shin Huang, and Donald B. Jump. “Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice.” J Lipid Res 55, no. 7 (July 2014): 1448–64. https://doi.org/10.1194/jlr.M050062.
       Full Text  Link to Item
    • Bartz, Sarah, Aaloke Mody, Christoph Hornik, James Bain, Michael Muehlbauer, Tonny Kiyimba, Elizabeth Kiboneka, et al. “Severe acute malnutrition in childhood: hormonal and metabolic status at presentation, response to treatment, and predictors of mortality.” J Clin Endocrinol Metab 99, no. 6 (June 2014): 2128–37. https://doi.org/10.1210/jc.2013-4018.
       Full Text  Link to Item
    • Kien, C Lawrence, Janice Y. Bunn, Robert Stevens, James Bain, Olga Ikayeva, Karen Crain, Timothy R. Koves, and Deborah M. Muoio. “Dietary intake of palmitate and oleate has broad impact on systemic and tissue lipid profiles in humans.” Am J Clin Nutr 99, no. 3 (March 2014): 436–45. https://doi.org/10.3945/ajcn.113.070557.
       Full Text  Link to Item
    • Mody, Aaloke, Sarah Bartz, Christoph P. Hornik, Tonny Kiyimba, James Bain, Michael Muehlbauer, Elizabeth Kiboneka, et al. “Effects of HIV infection on the metabolic and hormonal status of children with severe acute malnutrition.” Plos One 9, no. 7 (2014): e102233. https://doi.org/10.1371/journal.pone.0102233.
       Full Text  Link to Item
    • Bhattacharya, Sayanti, Christopher B. Granger, Damian Craig, Carol Haynes, James Bain, Robert D. Stevens, Elizabeth R. Hauser, et al. “Validation of the association between a branched chain amino acid metabolite profile and extremes of coronary artery disease in patients referred for cardiac catheterization.” Atherosclerosis 232, no. 1 (January 2014): 191–96. https://doi.org/10.1016/j.atherosclerosis.2013.10.036.
       Full Text  Link to Item
    • McDonnell, Eoin, Olga R. Ilkayeva, Robert D. Stevens, Michael J. Muehlbauer, James R. Bain, Tomas C. Becker, and Matthew D. Hirschey. “Loss of SIRT3 leads to a compensatory shift in cellular metabolism promoting cancer cell growth.” Cancer & Metabolism 2, no. Suppl 1 (January 2014): O18–O18. https://doi.org/10.1186/2049-3002-2-s1-o18.
       Full Text
    • Scholtens, Denise M., Michael J. Muehlbauer, Natalie R. Daya, Robert D. Stevens, Alan R. Dyer, Lynn P. Lowe, Boyd E. Metzger, et al. “Metabolomics reveals broad-scale metabolic perturbations in hyperglycemic mothers during pregnancy.” Diabetes Care 37, no. 1 (2014): 158–66. https://doi.org/10.2337/dc13-0989.
       Full Text  Link to Item
    • Patel, Mahesh J., Bryan C. Batch, Laura P. Svetkey, James R. Bain, Christy Boling Turer, Carol Haynes, Michael J. Muehlbauer, Robert D. Stevens, Christopher B. Newgard, and Svati H. Shah. “Race and sex differences in small-molecule metabolites and metabolic hormones in overweight and obese adults.” Omics 17, no. 12 (December 2013): 627–35. https://doi.org/10.1089/omi.2013.0031.
       Full Text  Link to Item
    • Jing, Enxuan, Brian T. O’Neill, Matthew J. Rardin, André Kleinridders, Olga R. Ilkeyeva, Siegfried Ussar, James R. Bain, et al. “Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation.” Diabetes 62, no. 10 (October 2013): 3404–17. https://doi.org/10.2337/db12-1650.
       Full Text  Link to Item
    • Ridaura, Vanessa K., Jeremiah J. Faith, Federico E. Rey, Jiye Cheng, Alexis E. Duncan, Andrew L. Kau, Nicholas W. Griffin, et al. “Gut microbiota from twins discordant for obesity modulate metabolism in mice.” Science 341, no. 6150 (September 6, 2013): 1241214. https://doi.org/10.1126/science.1241214.
       Full Text  Link to Item
    • Bain, James R., and Michael J. Muehlbauer. “Metabolomics reveals unexpected responses to oral glucose.” Diabetes 62, no. 8 (August 2013): 2651–53. https://doi.org/10.2337/db13-0605.
       Full Text  Link to Item
    • Batch, Bryan C., Svati H. Shah, Christopher B. Newgard, Christy B. Turer, Carol Haynes, James R. Bain, Michael Muehlbauer, et al. “Branched chain amino acids are novel biomarkers for discrimination of metabolic wellness.” Metabolism 62, no. 7 (July 2013): 961–69. https://doi.org/10.1016/j.metabol.2013.01.007.
       Full Text  Link to Item
    • Lowe, William L., and James R. Bain. “"Prediction is very hard, especially about the future": new biomarkers for type 2 diabetes?” Diabetes 62, no. 5 (May 2013): 1384–85. https://doi.org/10.2337/db13-0057.
       Full Text  Link to Item
    • Kien, C Lawrence, Janice Y. Bunn, Matthew E. Poynter, Robert Stevens, James Bain, Olga Ikayeva, Naomi K. Fukagawa, et al. “A lipidomics analysis of the relationship between dietary fatty acid composition and insulin sensitivity in young adults.” Diabetes 62, no. 4 (April 2013): 1054–63. https://doi.org/10.2337/db12-0363.
       Full Text  Link to Item
    • Patel, Sanjeet G., Jean W. Hsu, Farook Jahoor, Ivonne Coraza, James R. Bain, Robert D. Stevens, Dinakar Iyer, et al. “Pathogenesis of A⁻β⁺ ketosis-prone diabetes.” Diabetes 62, no. 3 (March 2013): 912–22. https://doi.org/10.2337/db12-0624.
       Full Text  Link to Item
    • York, Brian, Jørn V. Sagen, Anna Tsimelzon, Jean-Francios Louet, Atul R. Chopra, Erin L. Reineke, Suoling Zhou, et al. “Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family.” Mol Endocrinol 27, no. 2 (February 2013): 366–80. https://doi.org/10.1210/me.2012-1324.
       Full Text  Link to Item
    • Bain, James R. “Targeted metabolomics finds its mark in diabetes research.” Diabetes 62, no. 2 (February 2013): 349–51. https://doi.org/10.2337/db12-1189.
       Full Text  Link to Item
    • Chao, Lily C., Kevin Wroblewski, Olga R. Ilkayeva, Robert D. Stevens, James Bain, Gretchen A. Meyer, Simon Schenk, et al. “Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization.” J Lipid Res 53, no. 12 (December 2012): 2610–19. https://doi.org/10.1194/jlr.M029355.
       Full Text  Link to Item
    • Zhao, Mei, Yvonne Lamers, Maria A. Ralat, Bonnie S. Coats, Yueh-Yun Chi, Keith E. Muller, James R. Bain, et al. “Marginal vitamin B-6 deficiency decreases plasma (n-3) and (n-6) PUFA concentrations in healthy men and women.” J Nutr 142, no. 10 (October 2012): 1791–97. https://doi.org/10.3945/jn.112.163246.
       Full Text  Link to Item
    • Gaudet, Mia M., Roni T. Falk, Robert D. Stevens, Marc J. Gunter, James R. Bain, Ruth M. Pfeiffer, Nancy Potischman, et al. “Analysis of serum metabolic profiles in women with endometrial cancer and controls in a population-based case-control study.” J Clin Endocrinol Metab 97, no. 9 (September 2012): 3216–23. https://doi.org/10.1210/jc.2012-1490.
       Full Text  Link to Item
    • Kim, Dong-Hoon, Maureen A. Sartor, James R. Bain, Darleen Sandoval, Robert D. Stevens, Mario Medvedovic, Christopher B. Newgard, Stephen C. Woods, and Randy J. Seeley. “Rapid and weight-independent improvement of glucose tolerance induced by a peptide designed to elicit apoptosis in adipose tissue endothelium.” Diabetes 61, no. 9 (September 2012): 2299–2310. https://doi.org/10.2337/db11-1579.
       Full Text  Link to Item
    • Thompson, Dana K., Richard Sloane, James R. Bain, Robert D. Stevens, Christopher B. Newgard, Carl F. Pieper, and Virginia B. Kraus. “Daily Variation of Serum Acylcarnitines and Amino Acids.” Metabolomics 8, no. 4 (August 2012): 556–65. https://doi.org/10.1007/s11306-011-0345-9.
       Full Text  Link to Item
    • Shah, Svati H., Jie-Lena Sun, Robert D. Stevens, James R. Bain, Michael J. Muehlbauer, Karen S. Pieper, Carol Haynes, et al. “Baseline metabolomic profiles predict cardiovascular events in patients at risk for coronary artery disease.” Am Heart J 163, no. 5 (May 2012): 844-850.e1. https://doi.org/10.1016/j.ahj.2012.02.005.
       Full Text  Link to Item
    • Glynn, Erin L., Jie An, Li-Ping Wang, Olga R. Ilkayeva, Robert D. Stevens, James R. Bain, Michael J. Muehlbauer, et al. “Caloric restriction, aerobic exercise or a combination improves metabolic profiles following diet-induced obesity.” Faseb Journal 26 (April 1, 2012).
       Link to Item
    • Shah, S. H., D. R. Crosslin, C. S. Haynes, S. Nelson, C. B. Turer, R. D. Stevens, M. J. Muehlbauer, et al. “Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss.” Diabetologia 55, no. 2 (February 2012): 321–30. https://doi.org/10.1007/s00125-011-2356-5.
       Full Text  Link to Item
    • Ku, Bon Jeong, Tae Hoon Kim, Jae Hee Lee, Eric D. Buras, Lisa D. White, Robert D. Stevens, Olga R. Ilkayeva, et al. “Mig-6 plays a critical role in the regulation of cholesterol homeostasis and bile acid synthesis.” Plos One 7, no. 8 (2012): e42915. https://doi.org/10.1371/journal.pone.0042915.
       Full Text  Link to Item
    • Huffman, Kim M., Leanne M. Redman, Lawrence R. Landerman, Carl F. Pieper, Robert D. Stevens, Michael J. Muehlbauer, Brett R. Wenner, et al. “Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial.” Plos One 7, no. 4 (2012): e28190. https://doi.org/10.1371/journal.pone.0028190.
       Full Text  Open Access Copy  Link to Item
    • Brunner, Michael P., Svati H. Shah, Damian M. Craig, Robert D. Stevens, Michael J. Muehlbauer, James R. Bain, Christopher B. Newgard, et al. “Effect of heparin administration on metabolomic profiles in samples obtained during cardiac catheterization.” Circ Cardiovasc Genet 4, no. 6 (December 2011): 695–700. https://doi.org/10.1161/CIRCGENETICS.111.960575.
       Full Text  Link to Item
    • McNulty, Nathan P., Tanya Yatsunenko, Ansel Hsiao, Jeremiah J. Faith, Brian D. Muegge, Andrew L. Goodman, Bernard Henrissat, et al. “The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins.” Sci Transl Med 3, no. 106 (October 26, 2011): 106ra106. https://doi.org/10.1126/scitranslmed.3002701.
       Full Text  Link to Item
    • Lum, Helen, Richard Sloane, Kim M. Huffman, Virginia B. Kraus, Dana K. Thompson, William E. Kraus, James R. Bain, et al. “Plasma acylcarnitines are associated with physical performance in elderly men.” J Gerontol a Biol Sci Med Sci 66, no. 5 (May 2011): 548–53. https://doi.org/10.1093/gerona/glr006.
       Full Text  Link to Item
    • Laferrère, Blandine, David Reilly, Sara Arias, Nicholas Swerdlow, Prakash Gorroochurn, Baani Bawa, Mousumi Bose, et al. “Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss.” Sci Transl Med 3, no. 80 (April 27, 2011): 80re2. https://doi.org/10.1126/scitranslmed.3002043.
       Full Text  Link to Item
    • Gaudet, Mia M., Roni Falk, Robert D. Stevens, Ruth Pfeiffer, Nancy Potischman, Louise A. Brinton, Montserrat Garcia-Closas, et al. “Abstract LB-454: Serum metabolic profiles and endometrial cancer.” Cancer Research 71, no. 8_Supplement (April 15, 2011). https://doi.org/10.1158/1538-7445.am2011-lb-454.
       Full Text
    • Redman, Leanne M., Kim M. Huffman, Lawrence R. Landerman, Carl F. Pieper, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, et al. “Effect of caloric restriction with and without exercise on metabolic intermediates in nonobese men and women.” J Clin Endocrinol Metab 96, no. 2 (February 2011): E312–21. https://doi.org/10.1210/jc.2010-1971.
       Full Text  Link to Item
    • Huffman, Kim M., Cris A. Slentz, Lori A. Bateman, Dana Thompson, Michael J. Muehlbauer, James R. Bain, Robert D. Stevens, et al. “Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity.” Diabetes Care 34, no. 1 (January 2011): 174–76. https://doi.org/10.2337/dc10-0709.
       Full Text  Open Access Copy  Link to Item
    • Redman, Leanne M., Kim M. Huffman, Lawrence R. Landerman, Carl F. Pieper, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, et al. “Effect of Caloric Restriction with and without Exercise on Metabolic Intermediates in Nonobese Men and Women.” Endocrinology 152, no. 1 (January 1, 2011): 332–33. https://doi.org/10.1210/endo.152.1.9992.
       Full Text  Link to Item
    • Newgard, C. B., R. D. Stevens, B. R. Wenner, S. C. Burgess, O. Ilkayeva, M. J. Muehlbauer, A. Dean Sherry, and J. R. Bain. “Comprehensive Metabolic Analysis for Understanding of Disease,” December 1, 2010, 97–107. https://doi.org/10.1016/B978-0-12-374934-5.00009-X.
       Full Text
    • Louet, Jean-Francois, Atul R. Chopra, Jorn V. Sagen, Jie An, Brian York, Mounia Tannour-Louet, Pradip K. Saha, et al. “The coactivator SRC-1 is an essential coordinator of hepatic glucose production.” Cell Metab 12, no. 6 (December 1, 2010): 606–18. https://doi.org/10.1016/j.cmet.2010.11.009.
       Full Text  Link to Item
    • Wanic, K., A. Pazderska, S. Shah, D. O’Hanlon, J. R. Bain, R. D. Stevens, C. B. Newgard, and J. J. Nolan. “Early onset type 2 diabetes subjects have a metabolic signatures distinguishing them from BMI-matched normoglycaemic individuals.” Irish Journal of Medical Science 179 (November 1, 2010): 517–517.
       Link to Item
    • Rey, Federico E., Jeremiah J. Faith, James Bain, Michael J. Muehlbauer, Robert D. Stevens, Christopher B. Newgard, and Jeffrey I. Gordon. “Dissecting the in vivo metabolic potential of two human gut acetogens.” J Biol Chem 285, no. 29 (July 16, 2010): 22082–90. https://doi.org/10.1074/jbc.M110.117713.
       Full Text  Link to Item
    • Shah, Svati H., James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, David R. Crosslin, Carol Haynes, Jennifer Dungan, et al. “Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events.” Circ Cardiovasc Genet 3, no. 2 (April 2010): 207–14. https://doi.org/10.1161/CIRCGENETICS.109.852814.
       Full Text  Open Access Copy  Link to Item
    • Tai, E. S., M. L. S. Tan, R. D. Stevens, Y. L. Low, M. J. Muehlbauer, D. L. M. Goh, O. R. Ilkayeva, et al. “Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men.” Diabetologia 53, no. 4 (April 2010): 757–67. https://doi.org/10.1007/s00125-009-1637-8.
       Full Text  Link to Item
    • Wang, May-yun, Lijun Chen, Gregory O. Clark, Young Lee, Robert D. Stevens, Olga R. Ilkayeva, Brett R. Wenner, et al. “Leptin therapy in insulin-deficient type I diabetes.” Proc Natl Acad Sci U S A 107, no. 11 (March 16, 2010): 4813–19. https://doi.org/10.1073/pnas.0909422107.
       Full Text  Link to Item
    • Hirschey, Matthew D., Tadahiro Shimazu, Eric Goetzman, Enxuan Jing, Bjoern Schwer, David B. Lombard, Carrie A. Grueter, et al. “SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.” Nature 464, no. 7285 (March 4, 2010): 121–25. https://doi.org/10.1038/nature08778.
       Full Text  Link to Item
    • Bain, James R., Robert D. Stevens, Brett R. Wenner, Olga Ilkayeva, Deborah M. Muoio, and Christopher B. Newgard. “Metabolomics applied to diabetes research: moving from information to knowledge.” Diabetes 58, no. 11 (November 2009): 2429–43. https://doi.org/10.2337/db09-0580.
       Full Text  Link to Item
    • Huffman, Kim M., Svati H. Shah, Robert D. Stevens, James R. Bain, Michael Muehlbauer, Cris A. Slentz, Charles J. Tanner, et al. “Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women.” Diabetes Care 32, no. 9 (September 2009): 1678–83. https://doi.org/10.2337/dc08-2075.
       Full Text  Link to Item
    • Newgard, C. B., J. An, J. R. Bain, M. J. Muehlbauer, R. D. Stevens, L. F. Lien, A. M. Haqq, et al. “A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance (DOI:10.1016/j.cmet.2009.02.002).” Cell Metabolism 9, no. 6 (May 14, 2009): 565–66. https://doi.org/10.1016/j.cmet.2009.05.001.
       Full Text
    • Turer, Aslan T., Robert D. Stevens, James R. Bain, Michael J. Muehlbauer, Johannes van der Westhuizen, Joseph P. Mathew, Debra A. Schwinn, Donald D. Glower, Christopher B. Newgard, and Mihai V. Podgoreanu. “Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion.” Circulation 119, no. 13 (April 7, 2009): 1736–46. https://doi.org/10.1161/CIRCULATIONAHA.108.816116.
       Full Text  Link to Item
    • Newgard, Christopher B., Jie An, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, Lillian F. Lien, Andrea M. Haqq, et al. “A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance.” Cell Metab 9, no. 4 (April 2009): 311–26. https://doi.org/10.1016/j.cmet.2009.02.002.
       Full Text  Link to Item
    • Lien, Lillian F., Andrea M. Haqq, Michelle Arlotto, Cris A. Slentz, Michael J. Muehlbauer, Ross L. McMahon, James Rochon, et al. “The STEDMAN project: biophysical, biochemical and metabolic effects of a behavioral weight loss intervention during weight loss, maintenance, and regain.” Omics 13, no. 1 (February 2009): 21–35. https://doi.org/10.1089/omi.2008.0035.
       Full Text  Link to Item
    • Shah, Svati H., Elizabeth R. Hauser, James R. Bain, Michael J. Muehlbauer, Carol Haynes, Robert D. Stevens, Brett R. Wenner, et al. “High heritability of metabolomic profiles in families burdened with premature cardiovascular disease.” Mol Syst Biol 5 (2009): 258. https://doi.org/10.1038/msb.2009.11.
       Full Text  Link to Item
    • “Correction: Genetic Networks of Liver Metabolism Revealed by Integration of Metabolic and Transcriptional Profiling.” Plos Genetics 4, no. 7 (July 2008).
    • Ferrara, Christine T., Ping Wang, Elias Chaibub Neto, Robert D. Stevens, James R. Bain, Brett R. Wenner, Olga R. Ilkayeva, et al. “Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling.” Plos Genet 4, no. 3 (March 14, 2008): e1000034. https://doi.org/10.1371/journal.pgen.1000034.
       Full Text  Link to Item
    • Koves, Timothy R., John R. Ussher, Robert C. Noland, Dorothy Slentz, Merrie Mosedale, Olga Ilkayeva, James Bain, et al. “Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance.” Cell Metab 7, no. 1 (January 2008): 45–56. https://doi.org/10.1016/j.cmet.2007.10.013.
       Full Text  Link to Item
    • Levin, Malin C., Mara Monetti, Matthew J. Watt, Mini P. Sajan, Robert D. Stevens, James R. Bain, Christopher B. Newgard, and Robert V. Farese. “Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle.” Am J Physiol Endocrinol Metab 293, no. 6 (December 2007): E1772–81. https://doi.org/10.1152/ajpendo.00158.2007.
       Full Text  Link to Item
    • Monetti, Mara, Malin C. Levin, Matthew J. Watt, Mini P. Sajan, Stephen Marmor, Brian K. Hubbard, Robert D. Stevens, et al. “Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver.” Cell Metab 6, no. 1 (July 2007): 69–78. https://doi.org/10.1016/j.cmet.2007.05.005.
       Full Text  Link to Item
    • Zhang, Yong-Mei, Shigeru Chohnan, Kristopher G. Virga, Robert D. Stevens, Olga R. Ilkayeva, Brett R. Wenner, James R. Bain, et al. “Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis.” Chem Biol 14, no. 3 (March 2007): 291–302. https://doi.org/10.1016/j.chembiol.2007.01.013.
       Full Text  Link to Item
    • Qi, Ling, Jose E. Heredia, Judith Y. Altarejos, Robert Screaton, Naomi Goebel, Sherry Niessen, Ian X. Macleod, et al. “TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.” Science 312, no. 5781 (June 23, 2006): 1763–66. https://doi.org/10.1126/science.1123374.
       Full Text  Link to Item
    • Haqq, Andrea M., Lillian F. Lien, Jarol Boan, Michelle Arlotto, Cris A. Slentz, Michael J. Muehlbauer, James Rochon, et al. “The Study of the Effects of Diet on Metabolism and Nutrition (STEDMAN) weight loss project: Rationale and design.” Contemp Clin Trials 26, no. 6 (December 2005): 616–25. https://doi.org/10.1016/j.cct.2005.09.003.
       Full Text  Link to Item
    • Bain, James R., Jonathan C. Schisler, Koji Takeuchi, Christopher B. Newgard, and Thomas C. Becker. “An adenovirus vector for efficient RNA interference-mediated suppression of target genes in insulinoma cells and pancreatic islets of langerhans.” Diabetes 53, no. 9 (September 2004): 2190–94. https://doi.org/10.2337/diabetes.53.9.2190.
       Full Text  Link to Item
    • Bain, James R., and Allan S. Hoffman. “Tissue-culture surfaces with mixtures of aminated and fluorinated functional groups. Part 2. Growth and function of transgenic rat insulinoma cells (betaG I/17).” J Biomater Sci Polym Ed 14, no. 4 (2003): 341–67. https://doi.org/10.1163/156856203321478865.
       Full Text  Link to Item
    • Bain, James R., and Allan S. Hoffman. “Tissue-culture surfaces with mixtures of aminated and fluorinated functional groups. Part 1. Synthesis and characterization.” J Biomater Sci Polym Ed 14, no. 4 (2003): 325–39. https://doi.org/10.1163/156856203321478856.
       Full Text  Link to Item
    • Bain, James R., and Allan S. Hoffman. “Glycophase glass revisited: protein adsorption and cell growth on glass surfaces bearing immobilized glycerol monosaccharides.” Biomaterials 23, no. 16 (August 2002): 3347–57. https://doi.org/10.1016/s0142-9612(02)00035-2.
       Full Text  Link to Item
    • BAIN James R., Matthew D., Matthew D. KRAM Brian H., Matthew D. MISH Stanley L., and Matthew D. MUEHLBAUER Michael J. “RESPIRATORY AIDS,” 2002.
    • KRAM Brian H., Matthew D., Matthew D. MISH Stanley L., Matthew D. MUEHLBAUER Michael J., and Matthew D. BAIN James R. “RESPIRATORY AIDS,” 2000.
    • BRUCHMAN WILLIAM C, Matthew D., Matthew D. BOLTON CARL W, and Matthew D. BAIN JAMES R. “Prosthesis for tensile load-carrying tissue and method of manufacture,” 1993.
    • BRUCHMAN WILLIAM C, Matthew D., Matthew D. BOLTON CARL W, and Matthew D. BAIN JAMES R. “Prosthesis for tensile-load-carrying tissue and method of manufacture,” 1991.
    • Bruchman William Carl, Matthew D., Matthew D. Bolton Carl William, and Matthew D. Bain James Raymond. “A method of making a synthetic prosthesis for replacing or repair of ligaments or tendons,” 1986.
    • Bain James Raymond, Matthew D., Matthew D. Bolton Carl William, and Matthew D. Bruchman William Carl. “A synthetic prosthesis for replacement or repair of ligaments or tendons,” 1984.

  • Book Sections

    • Newgard, C. B., R. D. Stevens, B. R. Wenner, S. C. Burgess, O. Ilkayeva, M. J. Muehlbauer, A. D. Sherry, and J. R. Bain. “Comprehensive Metabolic Analysis for Understanding of Disease Mechanisms.” In Genomic and Personalized Medicine: V1-2, 180–92, 2008. https://doi.org/10.1016/B978-0-12-369420-1.00015-9.
       Full Text

  • Conference Papers

    • Giessner, Stephanie, Demitrius Hill, James R. Bain, Michael J. Muehlbauer, Adam C. Mincey, Andrea M. Haqq, Michael Freemark, and Pinar Gumus Balikcioglu. “Markers of Branched-Chain Amino Acid and Fat Metabolism in Obesity and Prader-Willi Syndrome.” In Hormone Research in Paediatrics, 95:182–83, 2022.
       Link to Item
    • ILAIWY, A. M. R. O., A. D. A. M. MINCEY, JAMES R. BAIN, M. I. C. H. A. E. L. MUEHLBAUER, J. O. N. A. T. H. A. N. CAMPBELL, and DAVID A. D’ALESSIO. “781-P: Beyond Glucosuria: Urine Metabolome Signature Associated with Dapagliflozin in Wild-Type Mice.” In Diabetes, Vol. 70. American Diabetes Association, 2021. https://doi.org/10.2337/db21-781-p.
       Full Text
    • LUNYERA, J. O. S. E. P. H., M. A. G. G. I. E. NGUYEN, CLARISSA J. DIAMANTIDIS, HAYDEN B. BOSWORTH, UPTAL D. PATEL, CLEMONTINA A. DAVENPORT, JAMES R. BAIN, et al. “526-P: Urine Tricarboxylic Acid Cycle Organic Anions and Progression of Diabetic Kidney Disease.” In Diabetes, Vol. 69. American Diabetes Association, 2020. https://doi.org/10.2337/db20-526-p.
       Full Text
    • White, R. E., K. Kavanagh, C. Sherrill, B. Uberseder, M. Bikdash, J. Bain, E. H. Chang, and K. A. Johnson. “Assessing Vascular Markers of Diabetic Disease Progression Through Contrast Enhanced Ultrasound.” In Ieee International Ultrasonics Symposium, Ius, 2019-October:1334–37, 2019. https://doi.org/10.1109/ULTSYM.2019.8926310.
       Full Text
    • Clinton, Chelsea M., James R. Bain, Michael J. Muehlbauer, Sara K. O’Neal, Brenna L. Hughes, Tracy Truong, Carl F. Pieper, Thomas F. McElrath, and Kelly K. Ferguson. “112: Urinary metabolomic profiles in pregnancy and association with fetal growth restriction.” In American Journal of Obstetrics and Gynecology, 220:S90–91. Elsevier BV, 2019. https://doi.org/10.1016/j.ajog.2018.11.133.
       Full Text
    • Parry, Traci L., Joseph W. Starnes, Amro Ilaiwy, James R. Bain, Mike J. Muehlbauer, Aubree Honcoop, Christopher B. Newgard, Peter Christopher, and Monte S. Willis. “Non-targeted Metabolomics Identifies Exercise-induced Cardioprotective Metabolic Pathways That Negate Ischemia Reperfusion Injury.” In Medicine &Amp; Science in Sports &Amp; Exercise, 49:158–158. Ovid Technologies (Wolters Kluwer Health), 2017. https://doi.org/10.1249/01.mss.0000517259.26486.93.
       Full Text
    • Ilaiwy, Amro, Traci L. Parry, James R. Bain, Michael J. Muehlbauer, Monte S. Willis, and Clark Files. “Muscle function recovery after acute lung injury is impaired in aged mice, linked in part, to metabolic alterations attributed to MuRF1 by quantitative targeted metabolomics analysis of acyl-carnitines.” In Faseb Journal, Vol. 30. FEDERATION AMER SOC EXP BIOL, 2016.
       Link to Item
    • Ilaiwy, Amro, Miao Liu, Traci S. Parry, James R. Bain, Mike J. Muehlbauer, Monte S. Willis, and Florin Despa. “Human amylin proteotoxicity impairs protein biosynthesis, and alters major cellular signaling pathways in the heart, brain and liver of humanized diabetic rat model in vivo.” In Faseb Journal, Vol. 30, 2016.
       Link to Item
    • Parry, Traci L., Joseph W. Starnes, Amro Ilaiwy, James R. Bain, Mike J. Muehlbauer, Aubree Honcoop, Christopher B. Newgard, Peter Christopher, and Monte S. Willis. “Non-targeted Metabolomics Identifies Exercise-induced Cardioprotective Metabolic Pathways That Negate Ischemia Reperfusion Injury.” In Medicine and Science in Sports and Exercise, 47:158–158. LIPPINCOTT WILLIAMS & WILKINS, 2015.
       Link to Item
    • Hunter, W., J. Kelly, D. Craig, C. Haynes, R. McGarrah, E. Velazquez, G. M. Felker, et al. “Metabolomic Profiling Identifies Biomarkers of Mitochondrial Function in Heart Failure with Preserved versus Reduced Ejection Fraction.” In Journal of the American College of Cardiology, 65:A774–A774, 2015. https://doi.org/10.1016/S0735-1097(15)60774-4.
       Full Text
    • Kelly, J. P., W. Hunter, D. Craig, C. Haynes, R. McGarrah, E. Velazquez, M. Felker, et al. “Metabolomic Profiling Identifies Biomarkers Predicting Adverse Outcomes in Patients with Heart Failure with Preserved Ejection Fraction.” In Journal of the American College of Cardiology, 65:A772–A772, 2015. https://doi.org/10.1016/S0735-1097(15)60772-0.
       Full Text
    • Siska, Peter J., Brice Weinberg, Arati V. Rao, James R. Bain, Michael J. Muehlbauer, Tingyu Liu, and Jeffrey Rathmell. “Acute and Chronic Lymphocytic Leukemia Induces Exhaustion and Suppresses Metabolic Reprogramming in T Cell Activation.” In Blood, Vol. 124. AMER SOC HEMATOLOGY, 2014.
       Link to Item
    • Aras, Mandar A., Damian M. Craig, Carol Haynes, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, Olga Ilkayeva, et al. “Peripheral Metabolite Profiles Predict Cardiomyopathy in a Cohort of Cardiac Catheterization Patients.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
       Link to Item
    • Tripathy, Sasmita, Robert D. Stevens, James R. Bain, Christopher B. Newgard, and Donald B. Jump. “Elevated hepatic fatty acid elongase-5 (Elovl5) attenuates fatty liver in high fat diet induced obese mice.” In Faseb Journal, Vol. 27. FEDERATION AMER SOC EXP BIOL, 2013.
       Link to Item
    • Glynn, Erin L., Jie An, Li-Ping Wang, Olga R. Ilkayeva, Robert D. Stevens, James R. Bain, Michael J. Muehlbauer, et al. “Caloric restriction, aerobic exercise or a combination improves metabolic profiles following diet-induced obesity.” In Faseb Journal, Vol. 26, 2012.
       Link to Item
    • Zhao, Mei, Yvonne Lamers, Maria A. Ralat, Bonnie S. Coats, Peter W. Stacpoole, Yueh-Yun Chi, Keith E. Muller, James R. Bain, Christopher B. Newgard, and Jesse F. Gregory. “Marginal Vitamin B6 Deficiency Affects Fatty Acid Profiles in Healthy Men and Women.” In Faseb Journal, Vol. 25. FEDERATION AMER SOC EXP BIOL, 2011.
       Link to Item
    • Brunner, Michael P., Svati H. Shah, Damian M. Craig, James R. Bain, Michael J. Muehlbauer, Christopher B. Newgard, William E. Kraus, Christopher B. Granger, Michael H. Sketch, and L Kristin Newby. “EFFECT OF HEPARIN ADMINISTRATION ON METABOLOMIC PROFILES FROM SAMPLES OBTAINED DURING CARDIAC CATHETERIZATION.” In Journal of the American College of Cardiology, 57:E1147–E1147. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)61147-9.
       Full Text
    • Wanic, K., A. Pazderska, S. Shah, D. O’Hanlon, J. R. Bain, R. D. Stevens, C. B. Newgard, and J. J. Nolan. “Distinctive metabolic signature in subjects with early onset type 2 diabetes.” In Diabetologia, Vol. 53. SPRINGER, 2010.
       Link to Item
    • Shah, Svati H., Jie-Lena Sun, Karen Pieper, David R. Crosslin, Carol Haynes, James R. Bain, Michael Muehlbauer, et al. “Plasma Metabolomic Profiles Predict Future Cardiovascular Events.” In Circulation, 120:S466–67. LIPPINCOTT WILLIAMS & WILKINS, 2009.
       Link to Item
    • Huffman, Kim M., Svati H. Shah, Robert D. Stevens, James R. Bain, and William E. Kraus. “Circulating metabolic intermediates are markers of insulin resistance in a population at risk for coronary heart disease.” In Circulation, Vol. 117. LIPPINCOTT WILLIAMS & WILKINS, 2008.
       Link to Item

  • Preprints

    • Ravi, Saranya, Traci L. Parry, Monte S. Willis, Pamela Lockyer, Cam Patterson, James R. Bain, Robert D. Stevens, Olga R. Ilkayeva, Christopher B. Newgard, and Jonathan C. Schisler. “Fenofibrate Induced Cardiac Fibrosis in Mice Deficient in the Protein Quality Control Regulator, CHIP.” MDPI AG, July 9, 2018. https://doi.org/10.20944/preprints201807.0137.v1.
       Full Text

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.