Overview
My research focuses on the characterization of cognitive change with age. I am specifically interested in delineating the change between normal and pathologic changes associated with aging and developing therapies to delay decline.
My area of expertise is neurodegenerative diseases and dementia with an emphasis on Alzheimer's disease.
Keywords: Alzheimer's disease.
My area of expertise is neurodegenerative diseases and dementia with an emphasis on Alzheimer's disease.
Keywords: Alzheimer's disease.
Current Appointments & Affiliations
Professor of Neurology
·
2012 - Present
Neurology, Behavioral Neurology,
Neurology
Professor in Psychiatry and Behavioral Sciences
·
2021 - Present
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences,
Psychiatry & Behavioral Sciences
Recent Publications
Amyloid-β PET scans, economic strain and financial decision-making among persons with cognitive impairment and care partners: a mixed-methods analysis of the CARE-IDEAS study.
Journal Article Alzheimers Res Ther · April 14, 2026 BACKGROUND: To explore the relationship between receipt of amyloid-β PET scan results and subsequent experiences of economic strain and financial decision-making for persons with cognitive impairment and their care partners. METHODS: A parallel convergent ... Full text Link to item CiteQuality-of-life factors at home and in health care settings for people living with dementia.
Journal Article Gerontologist · October 22, 2025 BACKGROUND AND OBJECTIVES: Person-centered "home time" measures track time spent in health care versus home using claims data. These measures can indicate patient preferences, quality of care, or quality of life. However, for people living with dementia, t ... Full text Link to item CiteMulti-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease.
Journal Article Genome Biol · July 17, 2025 BACKGROUND: Limited ancestral diversity has impaired our ability to detect risk variants more prevalent in ancestry groups of predominantly non-European ancestral background in genome-wide association studies (GWAS). We construct and analyze a multi-ancest ... Full text Link to item CiteRecent Grants
Pesticide Use and Markers of ADRD Neurodegeneration among US Farmers
ResearchCo Investigator · Awarded by Michigan State University · 2025 - 2030Cognitive Training to Reduce Cognitive Impairment: The PACT Trial
ResearchPhysician · Awarded by University of South Florida · 2021 - 2027AHEAD 3-45 Study: A Placebo-Controlled, Double-Blind, Parallel-Treatment Arm, 216 Week Study to Evaluate Efficacy and Safety of Treatment With BAN2401 in Subjects With Preclinical Alzheimer's Disease and Elevated Amyloid (A45 Trial) and in Subjects W
Clinical TrialPrincipal Investigator · Awarded by Eisai, Inc. · 2020 - 2026View All Grants
Education
State University of New York, Brooklyn ·
1985
M.D.
University of Tennessee, Knoxville ·
1981
Ph.D.