Overview
My research focuses on the characterization of cognitive change with age. I am specifically interested in delineating the change between normal and pathologic changes associated with aging and developing therapies to delay decline.
My area of expertise is neurodegenerative diseases and dementia with an emphasis on Alzheimer's disease.
Keywords: Alzheimer's disease.
My area of expertise is neurodegenerative diseases and dementia with an emphasis on Alzheimer's disease.
Keywords: Alzheimer's disease.
Current Appointments & Affiliations
Professor of Neurology
·
2012 - Present
Neurology, Behavioral Neurology,
Neurology
Professor in Psychiatry and Behavioral Sciences
·
2021 - Present
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences,
Psychiatry & Behavioral Sciences
Recent Publications
Quality-of-life factors at home and in health care settings for people living with dementia.
Journal Article Gerontologist · October 22, 2025 BACKGROUND AND OBJECTIVES: Person-centered "home time" measures track time spent in health care versus home using claims data. These measures can indicate patient preferences, quality of care, or quality of life. However, for people living with dementia, t ... Full text Link to item CiteMulti-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease.
Journal Article Genome Biol · July 17, 2025 BACKGROUND: Limited ancestral diversity has impaired our ability to detect risk variants more prevalent in ancestry groups of predominantly non-European ancestral background in genome-wide association studies (GWAS). We construct and analyze a multi-ancest ... Full text Link to item CiteBeta amyloid PET scans for dementia diagnoses: Practice and research implications from CARE-IDEAS.
Journal Article J Am Geriatr Soc · October 2024 Beta amyloid PET scans are a minimally invasive biomarker that may inform Alzheimer's disease (AD) diagnosis. The Caregiver's Reactions and Experience (CARE) study, an IDEAS supplement, aimed to understand experiences of PET scan recipients and their care ... Full text Link to item CiteRecent Grants
Pesticide Use and Markers of ADRD Neurodegeneration among US Farmers
ResearchCo Investigator · Awarded by Michigan State University · 2025 - 2030Cognitive Training to Reduce Cognitive Impairment: The PACT Trial
ResearchPhysician · Awarded by University of South Florida · 2021 - 2027AHEAD 3-45 Study: A Placebo-Controlled, Double-Blind, Parallel-Treatment Arm, 216 Week Study to Evaluate Efficacy and Safety of Treatment With BAN2401 in Subjects With Preclinical Alzheimer's Disease and Elevated Amyloid (A45 Trial) and in Subjects W
Clinical TrialPrincipal Investigator · Awarded by Eisai, Inc. · 2020 - 2026View All Grants
Education, Training & Certifications
State University of New York, Brooklyn ·
1985
M.D.
University of Tennessee, Knoxville ·
1981
Ph.D.