Scholars@Duke
James Steven Mills

James Steven Mills

Assistant Professor of Medicine
Medicine, Cardiology
james.s.mills@duke.edu
3320 Wake Forest Road, Suite 200, Raleigh, NC 27609
3320 Wake Forest Rd., Suite 200, Raleigh, NC 27609

Selected Publications

Point-of-care seeding of nitinol stents with blood-derived endothelial cells.

Journal Article J Biomed Mater Res B Appl Biomater · November 2016 Nitinol-based vascular devices, for example, peripheral and intracranial stents, are limited by thrombosis and restenosis. To ameliorate these complications, we developed a technology to promote vessel healing by rapidly seeding (QuickSeeding) autologous b ... Full text Link to item Cite

The impact of processes of care on myocardial infarct size in patients with ST-segment elevation myocardial infarction: observations from the CRISP-AMI trial.

Journal Article Clin Cardiol · January 2015 BACKGROUND: Primary percutaneous coronary intervention (PCI) is the most common method of reperfusion in patients with ST-segment elevation myocardial infarction (STEMI) in the United States. The intersection between processes of care and performance measu ... Full text Link to item Cite

Importance of total ischemic time and preprocedural infarct-related artery blood flow in predicting infarct size in patients with anterior wall myocardial infarction (from the CRISP-AMI Trial).

Journal Article Am J Cardiol · October 1, 2013 The goal of this study was to characterize determinants of infarct size in the multicenter randomized Counterpulsation to Reduce Infarct Size Pre-PCI Acute Myocardial Infarction (CRISP-AMI) trial. Contemporary determinants of infarct size in patients prese ... Full text Link to item Cite

Methods of creatine kinase-MB analysis to predict mortality in patients with myocardial infarction treated with reperfusion therapy.

Journal Article Trials · May 2, 2013 BACKGROUND: Larger infarct size measured by creatine kinase (CK)-MB release is associated with higher mortality and has been used as an important surrogate endpoint in the evaluation of new treatments for ST-segment elevation myocardial infarction (STEMI). ... Full text Open Access Link to item Cite

Prediction of enzymatic infarct size in ST-segment elevation myocardial infarction.

Journal Article Coron Artery Dis · March 2012 OBJECTIVES: Predictors of adverse outcomes following myocardial infarction (MI) are well established; however, little is known about what predicts enzymatically estimated infarct size in patients with acute ST-elevation MI. The Complement And Reduction of ... Full text Link to item Cite

Effect of peripheral arterial disease on functional and clinical outcomes in patients with heart failure (from HF-ACTION).

Journal Article Am J Cardiol · August 1, 2011 Patients with peripheral arterial disease (PAD) have lower functional capacity and worse clinical outcomes than age- and gender-matched patients. Few data exist on the relation of PAD to functional and clinical outcomes in patients with heart failure (HF). ... Full text Link to item Cite

A case of mistaken identity: persistent sciatic artery stenosis as a cause of critical limb ischemia.

Journal Article Catheter Cardiovasc Interv · February 1, 2011 Critical limb ischemia (CLI) is the most severe manifestation of peripheral arterial disease (PAD) and is defined as leg pain that occurs at rest, tissue ulceration, or gangrene. Initial diagnostic testing is often focused on localizing the level or site o ... Full text Link to item Cite

Preliminary observations using optical coherence tomography to assess neointimal coverage of a metal stent in a porcine model.

Journal Article Cardiovasc Revasc Med · 2009 BACKGROUND: Concerns surrounding late stent thrombosis have prompted the development of novel imaging techniques to assess neointimal coverage. Recent clinical studies have evaluated optical coherence tomography (OCT) to evaluate neointimal coverage, but p ... Full text Link to item Cite

REPAIR-AMI: stem cells for acute myocardial infarction.

Journal Article Future Cardiol · March 2007 Evaluation of: Schachinger V, Erbs S, Elsasser A et al.: Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N. Engl. J. Med. 355, 1210-1221 (2006). The Reinfusion of Enriched Progenitor cells And Infarct Remodeling in Acute ... Full text Link to item Cite