Overview
Medical Scientist Training Program
Recent Publications
Genetic disruption of WASHC4 drives endo-lysosomal dysfunction and cognitive-movement impairments in mice and humans.
Journal Article Elife · March 22, 2021 Mutation of the Wiskott-Aldrich syndrome protein and SCAR homology (WASH) complex subunit, SWIP, is implicated in human intellectual disability, but the cellular etiology of this association is unknown. We identify the neuronal WASH complex proteome, revea ... Full text Open Access Link to item CiteChemico-genetic discovery of astrocytic control of inhibition in vivo.
Journal Article Nature · December 2020 Perisynaptic astrocytic processes are an integral part of central nervous system synapses1,2; however, the molecular mechanisms that govern astrocyte-synapse adhesions and how astrocyte contacts control synapse formation and function are largely unknown. H ... Full text Link to item CiteRecent Grants
Interneuron Synapses: In Vivo Chemicogenetic Proteomics to Discover Developmental Brain Disorder Etiologies
FellowshipPI-Fellow · Awarded by National Institutes of Health · 2019 - 2022Gertrude B. Elion Mentored Medical Student Award
FellowshipPI-Fellow · Awarded by Triangle Community Foundation · 2019 - 2021View All Grants