Scholars@Duke

• Expertise
• 

  Subject Headings

  • Immunohistochemistry
  • Mice--Behavior
  • Molecular Biology
  • Proteomics
• Research
• 

  Selected Grants

  • Gertrude B. Elion Mentored Medical Student Award awarded by Triangle Community Foundation 2019 - 2021
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Courtland, Jamie L., Tyler Wa Bradshaw, Greg Waitt, Erik J. Soderblom, Tricia Ho, Anna Rajab, Ricardo Vancini, Il Hwan Kim, and Scott H. Soderling. “Genetic disruption of WASHC4 drives endo-lysosomal dysfunction and cognitive-movement impairments in mice and humans.” Elife 10 (March 22, 2021). https://doi.org/10.7554/eLife.61590.
       Full Text  Open Access Copy  Link to Item
    • Takano, Tetsuya, John T. Wallace, Katherine T. Baldwin, Alicia M. Purkey, Akiyoshi Uezu, Jamie L. Courtland, Erik J. Soderblom, et al. “Chemico-genetic discovery of astrocytic control of inhibition in vivo.” Nature 588, no. 7837 (December 2020): 296–302. https://doi.org/10.1038/s41586-020-2926-0.
       Full Text  Link to Item
    • Kim, Il Hwan, Namsoo Kim, Sunwhi Kim, Koji Toda, Christina M. Catavero, Jamie L. Courtland, Henry H. Yin, and Scott H. Soderling. “Dysregulation of the Synaptic Cytoskeleton in the PFC Drives Neural Circuit Pathology, Leading to Social Dysfunction.” Cell Rep 32, no. 4 (July 28, 2020): 107965. https://doi.org/10.1016/j.celrep.2020.107965.
       Full Text  Link to Item
    • Gao, Yudong, Erin Hisey, Tyler W. A. Bradshaw, Eda Erata, Walter E. Brown, Jamie L. Courtland, Akiyoshi Uezu, Yu Xiang, Yarui Diao, and Scott H. Soderling. “Plug-and-Play Protein Modification Using Homology-Independent Universal Genome Engineering.” Neuron 103, no. 4 (August 21, 2019): 583-597.e8. https://doi.org/10.1016/j.neuron.2019.05.047.
       Full Text  Link to Item
    • Iyer, Radhika, Lea Wehrmann, Rebecca L. Golden, Koumudi Naraparaju, Jamie L. Croucher, Suzanne P. MacFarland, Peng Guan, et al. “Entrectinib is a potent inhibitor of Trk-driven neuroblastomas in a xenograft mouse model.” Cancer Letters 372, no. 2 (March 2016): 179–86. https://doi.org/10.1016/j.canlet.2016.01.018.
       Full Text
    • Alferiev, Ivan S., Radhika Iyer, Jamie L. Croucher, Richard F. Adamo, Kehan Zhang, Jennifer L. Mangino, Venkatadri Kolla, et al. “Nanoparticle-mediated delivery of a rapidly activatable prodrug of SN-38 for neuroblastoma therapy.” Biomaterials 51 (May 2015): 22–29. https://doi.org/10.1016/j.biomaterials.2015.01.075.
       Full Text
    • Iyer, Radhika, Jamie L. Croucher, Michael Chorny, Jennifer L. Mangino, Ivan S. Alferiev, Robert J. Levy, Venkatadri Kolla, and Garrett M. Brodeur. “Nanoparticle delivery of an SN38 conjugate is more effective than irinotecan in a mouse model of neuroblastoma.” Cancer Letters 360, no. 2 (May 2015): 205–12. https://doi.org/10.1016/j.canlet.2015.02.011.
       Full Text
    • Croucher, Jamie L., Radhika Iyer, Nanxin Li, Valentina Molteni, Jon Loren, W Perry Gordon, Tove Tuntland, Bo Liu, and Garrett M. Brodeur. “TrkB inhibition by GNF-4256 slows growth and enhances chemotherapeutic efficacy in neuroblastoma xenografts.” Cancer Chemotherapy and Pharmacology 75, no. 1 (January 2015): 131–41. https://doi.org/10.1007/s00280-014-2627-1.
       Full Text
    • Brodeur, Garrett M., Radhika Iyer, Jamie L. Croucher, Tiangang Zhuang, Mayumi Higashi, and Venkatadri Kolla. “Therapeutic targets for neuroblastomas.” Expert Opinion on Therapeutic Targets 18, no. 3 (March 2014): 277–92. https://doi.org/10.1517/14728222.2014.867946.
       Full Text

  • Preprints

    • Courtland, Jamie L., Tyler W. A. Bradshaw, Greg Waitt, Erik J. Soderblom, Tricia Ho, Anna Rajab, Ricardo Vancini, Hwan Kim, and Scott H. Soderling. “Genetic Disruption of WASHC4 Drives Endo-lysosomal Dysfunction and Cognitive-Movement Impairments in Mice and Humans.” Cold Spring Harbor Laboratory, August 6, 2020. https://doi.org/10.1101/2020.08.06.239517.
       Full Text

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.