Janet Knight Horton | Scholars@Duke

Janet Knight Horton
Adjunct Associate Professor in the Department of Radiation Oncology

My primary clinical and research focus revolves around women with breast cancer. Specifically, I am interested in studying breast cancer subtype specific (luminal, basal) radiation response in human breast tumors and utilizing that information to design biologically based radiotherapy trials.

Current Appointments & Affiliations

Adjunct Associate Professor in the Department of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2018
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2013

Contact Information

201 Trent Drive, 05151A Morris Building, Box 3085, Durham, NC 27710
Department Of Radiation Oncolo, Box 3085, Durham, NC 27710
(919) 668-5213

Background
Education, Training, & Certifications
- M.D., Wake Forest University 2001
Duke Appointment History
- Associate Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2014 - 2018
- Assistant Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2008 - 2014
Research
Selected Grants
- Preoperative Breast Radiotherapy: A Tool to Provide Individualized and Biologically-Based Radiation Therapy awarded by Gateway for Cancer Research 2015 - 2019
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Blitzblau, RC, and Horton, JK. "First, Do No Harm." International Journal of Radiation Oncology, Biology, Physics 103, no. 2 (February 2019): 295-296. (Letter) Full Text
  - Natarajan, B, Spiegel, D, Nichols, EM, Feigenberg, S, Blitzblau, R, Broadwater, G, Duffy, EA, Baker, JA, and Horton, JK. "Findings on Surveillance Imaging After Preoperative Partial Breast Irradiation for Early Stage Breast Cancer." International Journal of Radiation Oncology, Biology, Physics 102, no. 4 (November 2018): 1374-1381. Full Text
  - Jagsi, R, Griffith, KA, Bellon, JR, Woodward, WA, Horton, JK, Ho, A, Feng, FY, Speers, C, Overmoyer, B, Sabel, M, Schott, AF, Pierce, L, and Translational Breast Cancer Research Consortium, . "Concurrent Veliparib With Chest Wall and Nodal Radiotherapy in Patients With Inflammatory or Locoregionally Recurrent Breast Cancer: The TBCRC 024 Phase I Multicenter Study." Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 36, no. 13 (May 2018): 1317-1322. Full Text
  - Rahal, OM, Wolfe, AR, Mandal, PK, Larson, R, Tin, S, Jimenez, C, Zhang, D, Horton, J, Reuben, JM, McMurray, JS, and Woodward, WA. "Blocking Interleukin (IL)4- and IL13-Mediated Phosphorylation of STAT6 (Tyr641) Decreases M2 Polarization of Macrophages and Protects Against Macrophage-Mediated Radioresistance of Inflammatory Breast Cancer." International Journal of Radiation Oncology, Biology, Physics 100, no. 4 (March 2018): 1034-1043. Full Text
  - Ryser, MD, Horton, JK, and Hwang, ES. "How Low Can We Go-and Should We? Risk Reduction for Minimal-Volume DCIS." Annals of surgical oncology 25, no. 2 (February 2018): 354-355. Full Text
  - Horton, JK, Jagsi, R, Woodward, WA, and Ho, A. "Breast Cancer Biology: Clinical Implications for Breast Radiation Therapy." International Journal of Radiation Oncology, Biology, Physics 100, no. 1 (January 2018): 23-37. (Review) Full Text
  - Horton, JK. "Postmastectomy Conundrum." International journal of radiation oncology, biology, physics 98, no. 5 (August 2017): 976-. (Letter) Full Text
  - Lee, C-T, Zhou, Y, Roy-Choudhury, K, Siamakpour-Reihani, S, Young, K, Hoang, P, Kirkpatrick, JP, Chi, J-TA, Dewhirst, MW, and Horton, JK. "Subtype-Specific Radiation Response and Therapeutic Effect of FAS Death Receptor Modulation in Human Breast Cancer." Radiation Research 188, no. 2 (August 2017): 169-180. Full Text
  - Greenup, RA, Blitzblau, RC, Houck, KL, Sosa, JA, Horton, J, Peppercorn, JM, Taghian, AG, Smith, BL, and Hwang, ES. "Cost Implications of an Evidence-Based Approach to Radiation Treatment After Lumpectomy for Early-Stage Breast Cancer." Journal of Oncology Practice 13, no. 4 (April 2017): e283-e290. Full Text
  - Morrow, M, Van Zee, KJ, Solin, LJ, Houssami, N, Chavez-MacGregor, M, Harris, JR, Horton, J, Hwang, S, Johnson, PL, Marinovich, ML, Schnitt, SJ, Wapnir, I, and Moran, MS. "Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma In Situ." Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 34, no. 33 (November 2016): 4040-4046. Full Text
  - Morrow, M, Van Zee, KJ, Solin, LJ, Houssami, N, Chavez-MacGregor, M, Harris, JR, Horton, J, Hwang, S, Johnson, PL, Marinovich, ML, Schnitt, SJ, Wapnir, I, and Moran, MS. "Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery with Whole-Breast Irradiation in Ductal Carcinoma In Situ." Annals of surgical oncology 23, no. 12 (November 2016): 3801-3810. (Review) Full Text
  - Sheng, Y, Li, T, Yoo, S, Yin, FF, Blitzblau, RC, Horton, JK, Palta, M, Hahn, CA, Ge, Y, and Wu, QR. "Development of an Ultra-Fast, High-Quality Whole-Breast Radiation Therapy Treatment Planning System." International journal of radiation oncology, biology, physics 96, no. 2S (October 2016): S228-. Full Text
  - Spiegel, D, Marcom, PK, Peterson, B, Force, J, Howie, L, Palta, M, Blitzblau, RC, and Horton, JK. "Acute Toxicity in Patients With HER2-Positive Breast Cancer Treated With Adjuvant Radiation Therapy and Concurrent Trastuzumab and Pertuzumab." International journal of radiation oncology, biology, physics 96, no. 2S (October 2016): E9-E10. Full Text
  - Wang, C, Horton, JK, Yin, F-F, and Chang, Z. "Assessment of Treatment Response With Diffusion-Weighted MRI and Dynamic Contrast-Enhanced MRI in Patients With Early-Stage Breast Cancer Treated With Single-Dose Preoperative Radiotherapy: Initial Results." Technology in Cancer Research & Treatment 15, no. 5 (October 2016): 651-660. Full Text
  - Wang, C, Horton, JK, Yin, FF, Subashi, E, and Chang, Z. "Early-Stage Breast Radiation Therapy Assessment Using Transcytolemmal Water Exchange Analysis of DCE-Magnetic Resonance Imaging: Initial Results." International journal of radiation oncology, biology, physics 96, no. 2S (October 2016): E617-. Full Text
  - Yoo, S, Horton, JK, Yin, FF, and Blitzblau, RC. "Dosimetric Effect of the Breast Board and Couch Top for Whole-Breast Radiation Therapy in the Prone Position." International journal of radiation oncology, biology, physics 96, no. 2S (October 2016): E46-E47. Full Text
  - Morrow, M, Van Zee, KJ, Solin, LJ, Houssami, N, Chavez-MacGregor, M, Harris, JR, Horton, J, Hwang, S, Johnson, PL, Marinovich, ML, Schnitt, SJ, Wapnir, I, and Moran, MS. "Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma in Situ." Practical Radiation Oncology 6, no. 5 (September 2016): 287-295. Full Text
  - Horton, JK. "Integration of a Radiosensitivity Molecular Signature into the Assessment of Local Recurrence Risk in Breast Cancer." Breast Diseases 27, no. 1 (January 1, 2016): 76-77. Full Text
  - Kent, C, Horton, J, Blitzblau, R, and Koontz, BF. "Whose Disease Will Recur After Mastectomy for Early Stage, Node-Negative Breast Cancer? A Systematic Review." Clinical Breast Cancer 15, no. 6 (December 2015): 403-412. (Review) Full Text
  - Horton, JK, Siamakpour-Reihani, S, Lee, C-T, Zhou, Y, Chen, W, Geradts, J, Fels, DR, Hoang, P, Ashcraft, KA, Groth, J, Kung, H-N, Dewhirst, MW, and Chi, J-TA. "FAS Death Receptor: A Breast Cancer Subtype-Specific Radiation Response Biomarker and Potential Therapeutic Target." Radiation research 184, no. 5 (November 2015): 456-469. Full Text
  - Siamakpour-Reihani, S, Owzar, K, Jiang, C, Turner, T, Deng, Y, Bean, SM, Horton, JK, Berchuck, A, Marks, JR, Dewhirst, MW, and Alvarez Secord, A. "Prognostic significance of differential expression of angiogenic genes in women with high-grade serous ovarian carcinoma." Gynecologic oncology 139, no. 1 (October 2015): 23-29. Full Text
  - Blitzblau, RC, Arya, R, Yoo, S, Baker, JA, Chang, Z, Palta, M, Duffy, E, and Horton, JK. "A phase 1 trial of preoperative partial breast radiation therapy: Patient selection, target delineation, and dose delivery." Practical radiation oncology 5, no. 5 (September 2015): e513-e520. Full Text
  - Arya, R, Siamakpour-Reihani, S, Palta, M, Massa, L, Broadwater, G, Blitzblau, RC, and Horton, JK. "Exercise behavior and patient-reported outcomes in women with early breast cancer receiving locoregional radiation therapy." Practical radiation oncology 5, no. 4 (July 2015): e275-e281. Full Text
  - Horton, JK, Blitzblau, RC, Yoo, S, Geradts, J, Chang, Z, Baker, JA, Georgiade, GS, Chen, W, Siamakpour-Reihani, S, Wang, C, Broadwater, G, Groth, J, Palta, M, Dewhirst, M, Barry, WT, Duffy, EA, Chi, J-TA, and Hwang, ES. "Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1, Dose-Escalation Protocol With Radiation Response Biomarkers." International journal of radiation oncology, biology, physics 92, no. 4 (July 2015): 846-855. Full Text
  - Siamakpour-Reihani, S, Owzar, K, Jiang, C, Scarbrough, PM, Craciunescu, OI, Horton, JK, Dressman, HK, Blackwell, KL, and Dewhirst, MW. "Genomic profiling in locally advanced and inflammatory breast cancer and its link to DCE-MRI and overall survival." International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 31, no. 4 (June 2015): 386-395. Full Text
  - Yoo, S, Blitzblau, R, Yin, F-F, and Horton, JK. "Dosimetric comparison of preoperative single-fraction partial breast radiotherapy techniques: 3D CRT, noncoplanar IMRT, coplanar IMRT, and VMAT." Journal of applied clinical medical physics 16, no. 1 (January 8, 2015): 5126-. Full Text
  - Horton, JK, and Bellon, JR. "Oncology scandquality of life and patient perspectives during breast radiation therapy." International Journal of Radiation Oncology Biology Physics 91, no. 2 (January 1, 2015): 249-251. (Review) Full Text
  - Horton, JK. "First results of the preoperative accelerated partial breast irradiation (PAPBI) trial." Breast Diseases 26, no. 4 (January 1, 2015): 341-342. Full Text
  - McGuire, KP, Hwang, ES, Cantor, A, Golshan, M, Meric-Bernstam, F, Horton, JK, Nanda, R, Amos, KD, Forero, A, Hudis, CA, Meszoely, I, and De Los Santos, JF. "Surgical patterns of care in patients with invasive breast cancer treated with neoadjuvant systemic therapy and breast magnetic resonance imaging: results of a secondary analysis of TBCRC 017." Annals of Surgical Oncology 22, no. 1 (January 2015): 75-81. Full Text
  - Palta, M, Palta, P, Bhavsar, NA, Horton, JK, and Blitzblau, RC. "The use of adjuvant radiotherapy in elderly patients with early-stage breast cancer: Changes in practice patterns after publication of Cancer and Leukemia Group B 9343." Cancer 121, no. 2 (January 1, 2015): 188-193. Full Text
  - Siamakpour-Reihani, S, Owzar, K, Jiang, C, Turner, T, Deng, Y, Bean, SM, Horton, JK, Berchuck, A, Marks, JR, Dewhirst, MW, and Secord, AA. "Prognostic significance of differential expression of angiogenic genes in women with high-grade serous ovarian carcinoma." Gynecologic Oncology 139, no. 1 (2015): 23-29. Full Text
  - Yoo, S, Blitzblau, R, Yin, FF, and Horton, JK. "Dosimetric comparison of preoperative single-fraction partial breast radiotherapy techniques: 3D CRT, noncoplanar IMRT, coplanar IMRT, and VMAT." Journal of Applied Clinical Medical Physics 16, no. 1 (January 1, 2015): 183-191.
  - Horton, JK, Dewhirst, MW, Siamakpour-Reihani, S, Zhou, Y, Geradts, J, Chi, J-TA, and Chen, W. "Changes in Gene Expression After Radiation in Human Breast Cancers: A Guide to Predicting and Modulating Radiation Response." JOURNAL OF WOMENS HEALTH 23, no. 10 (October 1, 2014): 861-861. Link to Item
  - Moran, MS, Schnitt, SJ, Giuliano, AE, Harris, JR, Khan, SA, Horton, J, Klimberg, S, Chavez-MacGregor, M, Freedman, G, Houssami, N, Johnson, PL, and Morrow, M. "Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer." Journal of Clinical Oncology 32, no. 14 (May 10, 2014): 1507-1515. Full Text
  - Moran, MS, Schnitt, SJ, Giuliano, AE, Harris, JR, Khan, SA, Horton, J, Klimberg, S, Chavez-MacGregor, M, Freedman, G, Houssami, N, Johnson, PL, Morrow, M, Society of Surgical Oncology, , and American Society for Radiation Oncology, . "Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer." Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 32, no. 14 (May 2014): 1507-1515. Full Text
  - Horton, JK. "Prospective multicenter trial evaluating balloon-catheter partial-breast irradiation for ductal carcinoma in situ." Breast Diseases 25, no. 1 (March 17, 2014): 80-81. Full Text
  - Moran, MS, Schnitt, SJ, Giuliano, AE, Harris, JR, Khan, SA, Horton, J, Klimberg, S, Chavez-MacGregor, M, Freedman, G, Houssami, N, Johnson, PL, and Morrow, M. "Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer." International Journal of Radiation Oncology, Biology, Physics 88, no. 3 (March 2014): 553-564. Full Text
  - Moran, MS, Schnitt, SJ, Giuliano, AE, Harris, JR, Khan, SA, Horton, J, Klimberg, S, Chavez-MacGregor, M, Freedman, G, Houssami, N, Johnson, PL, and Morrow, M. "Society of Surgical Oncology–American Society for Radiation Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Stages I and II Invasive Breast Cancer." Annals of Surgical Oncology 21, no. 3 (March 2014): 704-716. Full Text
  - Moran, MS, Schnitt, SJ, Giuliano, AE, Harris, JR, Khan, SA, Horton, J, Klimberg, S, Chavez-MacGregor, M, Freedman, G, Houssami, N, Johnson, PL, and Morrow, M. "Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer." Annals of Surgical Oncology 21, no. 3 (March 2014): 704-716. Full Text
  - Qiu, J-J, Chang, Z, Horton, JK, Wu, Q-RJ, Yoo, S, and Yin, F-F. "Dosimetric comparison of 3D conformal, IMRT, and V-MAT techniques for accelerated partial-breast irradiation (APBI)." Medical dosimetry : official journal of the American Association of Medical Dosimetrists 39, no. 2 (January 27, 2014): 152-158. Full Text
  - Horton, JK. "Effect of local therapy on locoregional recurrence in postmenopausal women with breast cancer in the Tamoxifen Exemestane Adjuvant Multinational (TEAM) trial." Breast Diseases: a Year Book Quarterly 25, no. 2 (2014): 179-180. Full Text
  - McGuire, KP, Hwang, ES, Cantor, A, Golshan, M, Meric-Bernstam, F, Horton, JK, Nanda, R, Amos, KD, Forero, A, Hudis, CA, Meszoely, I, and Santos, JFDL. "Surgical Patterns of Care in Patients with Invasive Breast Cancer Treated with Neoadjuvant Systemic Therapy and Breast Magnetic Resonance Imaging: Results of a Secondary Analysis of TBCRC 017." Annals of Surgical Oncology 22, no. 1 (2014): 75-81. Full Text
  - Qiu, JJ, Chang, Z, Horton, JK, Wu, QRJ, Yoo, S, and Yin, FF. "Dosimetric comparison of 3D conformal, IMRT, and V-MAT techniques for accelerated partial-breast irradiation (APBI)." Medical Dosimetry 39, no. 2 (January 1, 2014): 152-158. Full Text
  - Horton, JK, Chi, J-TA, Groth, J, Zhou, Y, Lee, C-T, and Geradts, J. "Up-regulation of Fas Expression in Human Breast Carcinomas Treated With Preoperative Radiation." JOURNAL OF WOMENS HEALTH 22, no. 10 (October 1, 2013): 890-890. Link to Item
  - De Los Santos, JF, Cantor, A, Amos, KD, Forero, A, Golshan, M, Horton, JK, Hudis, CA, Hylton, NM, McGuire, K, Meric-Bernstam, F, Meszoely, IM, Nanda, R, and Hwang, ES. "Magnetic resonance imaging as a predictor of pathologic response in patients treated with neoadjuvant systemic treatment for operable breast cancer. Translational Breast Cancer Research Consortium trial 017." Cancer 119, no. 10 (May 2013): 1776-1783. Full Text
  - Horton, JK, and Jagsi, R. "Oncology scan - Breast cancers." International Journal of Radiation Oncology Biology Physics 85, no. 5 (April 1, 2013): 1151-1152. Full Text
  - Lyman, GH, Baker, J, Geradts, J, Horton, J, Kimmick, G, Peppercorn, J, Pruitt, S, Scheri, RP, and Hwang, ES. "Multidisciplinary care of patients with early-stage breast cancer." Surg Oncol Clin N Am 22, no. 2 (April 2013): 299-317. (Review) Full Text Link to Item
  - Blitzblau, RC, and Horton, JK. "Radiotherapy After Mastectomy." Surgical Oncology Clinics of North America (2013). Full Text
  - Blitzblau, RC, and Horton, JK. "Radiotherapy After Mastectomy." Surgical Oncology Clinics of North America 22, no. 3 (2013): 563-577. Full Text
  - Blitzblau, RC, and Horton, JK. "Treatment planning technique in patients receiving postmastectomy radiation therapy." Practical Radiation Oncology 3, no. 4 (2013): 241-248. Full Text
  - Santos, JFDL, Cantor, A, Amos, KD, Forero, A, Golshan, M, Horton, JK, Hudis, CA, Hylton, NM, McGuire, K, Meric-Bernstam, F, Meszoely, IM, Nanda, R, and Hwang, ES. "Magnetic resonance imaging as a predictor of pathologic response in patients treated with neoadjuvant systemic treatment for operable breast cancer: Translational Breast Cancer Research Consortium trial 017." Cancer 119, no. 10 (2013): 1776-1783. Full Text
  - Horton, JK, Fels, DR, Kung, H-N, Zhou, Y, Ashcraft, K, Dewhirst, MW, and Chi, J-TA. "Differential Activation of Cell Death Pathways After Ionizing Radiation in Luminal and Basal Breast Cancer Cell Lines." JOURNAL OF WOMENS HEALTH 21, no. 10 (October 2012): 992-992. Link to Item
  - Cuneo, KC, Dash, RC, Wilke, LG, Horton, JK, and Koontz, BF. "Risk of invasive breast cancer and ductal carcinoma in situ in women with atypical papillary lesions of the breast." Breast J 18, no. 5 (September 2012): 475-478. Full Text Link to Item
  - Moran, MS, and Horton, JK. "Oncology Scan – Breast Cancer." International Journal of Radiation Oncology*Biology*Physics 84, no. 1 (September 2012): 1-3. Full Text
  - Yoo, S, Wu, Q, O'Daniel, J, Horton, J, and Yin, F-F. "Comparison of 3D conformal breast radiation treatment plans using the anisotropic analytical algorithm and pencil beam convolution algorithm." Radiother Oncol 103, no. 2 (May 2012): 172-177. Full Text Link to Item
  - Betof, AS, Rabbani, ZN, Hardee, ME, Kim, SJ, Broadwater, G, Bentley, RC, Snyder, SA, Vujaskovic, Z, Oosterwijk, E, Harris, LN, Horton, JK, Dewhirst, MW, and Blackwell, KL. "Carbonic anhydrase IX is a predictive marker of doxorubicin resistance in early-stage breast cancer independent of HER2 and TOP2A amplification." Br J Cancer 106, no. 5 (February 28, 2012): 916-922. Full Text Link to Item
  - Blitzblau, RC, and Horton, JK. "Treatment planning technique in patients receiving postmastectomy radiation therapy." Practical Radiation Oncology (2012). Full Text
  - Blitzblau, RC, and Horton, JK. "Evaluation of Single Nucleotide Polymorphisms (SNPs) in the p53 binding protein 1 (TP53BP1) gene in breast cancer patients treated with breast-conserving surgery and whole-breast irradiation (BCS+RT)." Breast Diseases: a Year Book Quarterly 23, no. 1 (January 2012): 44-45. Full Text
  - Kimple, RJ, Horton, JK, Livasy, CA, Shields, JM, Lawrence, JA, Chiu, WM, Ivanova, A, Ollila, DW, Carey, LA, Halle, JS, Sartor, CI, and Dees, EC. "Phase I study and biomarker analysis of lapatinib and concurrent radiation for locally advanced breast cancer." The Oncologist 17, no. 12 (January 2012): 1496-1503. Full Text
  - Palta, M, Yoo, S, Adamson, JD, Prosnitz, LR, and Horton, JK. "Preoperative single fraction partial breast radiotherapy for early-stage breast cancer." International Journal of Radiation Oncology, Biology, Physics 82, no. 1 (January 2012): 37-42. Full Text
  - Horton, JK, Fels, DR, Kung, H-N, Dewhirst, MW, and Chi, J-TA. "Gene Expression Response of Luminal and Basal Breast Cancer Cell Lines to Ionizing Radiation." JOURNAL OF WOMENS HEALTH 20, no. 10 (October 2011): 1404-1405. Link to Item
  - Horton, JK, Gleason, JF, Klepin, HD, Isom, S, Fried, DB, and Geiger, AM. "Age-related disparities in the use of radiotherapy for treatment of localized soft tissue sarcoma." Cancer 117, no. 17 (September 2011): 4033-4040. Full Text
  - Horton, JK. "Five-year analysis of treatment efficacy and cosmesis by the American Society of Breast Surgeons MammoSite breast brachytherapy registry trial in patients treated with accelerated partial breast irradiation." Breast Diseases 22, no. 3 (August 30, 2011): 299-300. Full Text
  - Palta, M, and Horton, JK. "In response to Drs. Kim and Shaitelman." International Journal of Radiation Oncology Biology Physics 80, no. 1 (May 1, 2011): 315-null. (Letter) Full Text
  - Horton, JK, Fels, DR, Chi, JA, Kung, H, Kirkpatrick, JP, and Dewhirst, M. "Protein Pathway Activation after Ionizing Radiation in Luminal and Basal Breast Cancer Cell Lines." INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 81, no. 2 (2011): S160-S161. Full Text Link to Item
  - Shah, MM, Horton, JK, Yoo, S, Hubbs, JL, Demirci, S, Light, KL, Temple, K, Patrone, M, and Marks, LB. "A comparison of clinical and dosimetric outcomes in patients receiving partial breast irradiation with photon-only versus mixed photon/electron treatment plans." Med Dosim 36, no. 4 (2011): 423-428. Full Text Link to Item
  - Qiu, J-J, Chang, Z, Wu, QJ, Yoo, S, Horton, J, and Yin, F-F. "Impact of volumetric modulated arc therapy technique on treatment with partial breast irradiation." Int J Radiat Oncol Biol Phys 78, no. 1 (September 1, 2010): 288-296. Full Text Link to Item
  - Horton, JK, Halle, J, Ferraro, M, Carey, L, Moore, DT, Ollila, D, and Sartor, CI. "Radiosensitization of chemotherapy-refractory, locally advanced or locally recurrent breast cancer with trastuzumab: a phase II trial." Int J Radiat Oncol Biol Phys 76, no. 4 (March 15, 2010): 998-1004. Full Text Link to Item
  - Prosnitz, LR, Horton, J, and Wallner, PE. "Accelerated partial breast irradiation: caution and concern from an ASTRO task force." Int J Radiat Oncol Biol Phys 74, no. 4 (July 15, 2009): 981-984. Full Text Link to Item
  - Godat, LN, Horton, JK, Shen, P, Stewart, JH, Wentworth, S, and Levine, EA. "Recurrence after mastectomy for ductal carcinoma in situ." The American surgeon 75, no. 7 (July 2009): 592-595.
  - Lally, BE, Geiger, AM, Urbanic, JJ, Butler, JM, Wentworth, S, Perry, MC, Wilson, LD, Horton, JK, Detterbeck, FC, Miller, AA, Thomas, CR, and Blackstock, AW. "Trends in the outcomes for patients with limited stage small cell lung cancer: An analysis of the Surveillance, Epidemiology, and End Results database." Lung Cancer 64, no. 2 (May 2009): 226-231. Full Text Link to Item
  - Horton, JK, Halle, JS, Chang, SX, and Sartor, CI. "Comparison of three concomitant boost techniques for early-stage breast cancer." Int J Radiat Oncol Biol Phys 64, no. 1 (January 1, 2006): 168-175. Full Text Link to Item
  - Horton, JK, and Tepper, JE. "Staging of colorectal cancer: past, present, and future." Clin Colorectal Cancer 4, no. 5 (January 2005): 302-312. (Review) Link to Item
  - Horton, JK. "Hospice. Care when there is no cure." N C Med J 62, no. 2 (March 2001): 86-90. Link to Item
- Book Sections
  - Mowery, YM, Yu, CX, and Horton, JK. "Preoperative partial breast." In Short Course Breast Radiotherapy: A Comprehensive Review of Hypofractionation, Partial Breast, and Intra-Operative Irradiation, 415-440. January 1, 2015. Full Text
- Conference Papers
  - Sheng, Y, Li, T, Yoo, S, Yin, FF, Blitzblau, RC, Sr, HJK, Palta, M, Hahn, CA, Ge, Y, and Wu, QRJ. "Development of an Ultra-Fast, High-Quality Whole-Breast Radiation Therapy Treatment Planning System." October 1, 2016. Full Text Link to Item
  - Spiegel, D, Marcom, K, Peterson, B, Force, J, Howie, L, Palta, M, Blitzblau, RC, and Sr, HJK. "Acute Toxicity in Patients With HER2-Positive Breast Cancer Treated With Adjuvant Radiation Therapy and Concurrent Trastuzumab and Pertuzumab." October 1, 2016. Full Text Link to Item
  - Wang, C, Sr, HJK, Yin, FF, Subashi, E, and Chang, Z. "Early-Stage Breast Radiation Therapy Assessment Using Transcytolemmal Water Exchange Analysis of DCE-Magnetic Resonance Imaging: Initial Results." October 1, 2016. Full Text Link to Item
  - Yoo, S, Sr, HJK, Yin, FF, and Blitzblau, RC. "Dosimetric Effect of the Breast Board and Couch Top for Whole-Breast Radiation Therapy in the Prone Position." October 1, 2016. Full Text Link to Item
  - Adamson, J, Chang, Z, Cai, J, Palta, M, Horton, J, Yin, F, and Blitzblau, R. "Induction of Gradual Changes in Blood Oxygen Levels in Post Lumpectomy Breast Tissue With Breath Holding: Results of a Pilot Study." November 2015. Full Text
  - Horton, J, Baker, J, Blitzblau, R, Georgiade, G, Hwang, E, Duffy, E, Morgan, M, Feigenberg, S, Citron, W, Kesmodel, S, Bellavance, E, Drogula, C, Tkaczuk, K, Galandak, J, and Nichols, E. "Preoperative Partial Breast Radiation Therapy: Short-term Imaging Outcomes With Two Unique Treatment Regimens." November 2015. Full Text
  - Jagsi, R, Griffith, KA, Bellon, JR, Woodward, WA, Horton, JK, Ho, AY, Schott, A, and Pierce, LJ. "TBCRC 024 Initial Results: A Multicenter Phase 1 Study of Veliparib Administered Concurrently With Chest Wall and Nodal Radiation Therapy in Patients With Inflammatory or Locoregionally Recurrent Breast Cancer." November 2015. Full Text
  - Nichols, E, Feigenberg, S, Morgan, M, Citron, W, Kesmodel, S, Bellavance, E, Drogula, C, Tkaczuk, K, Rosenblatt, P, Georgiade, G, Hwang, E, Broadwater, G, Duffy, E, Blitzblau, R, and Horton, J. "Preoperative External Beam APBI: Report of Acute Toxicities From 2 Prospective Clinical Trials Using Two Different Fractionation Schemes." November 2015. Full Text
  - Wang, C, Horton, J, Yin, F, and Chang, Z. "Treatment Assessment Using Dynamic Fractal Signature Dissimilarity as a Novel Biomarker for Early-Stage Breast Cancer Radiation Therapy: A Feasibility Study." November 2015. Full Text
  - Yoo, S, Horton, J, Yin, F, and Blitzblau, R. "Dosimetric Effect of the Prone Breast Board and the Couch Top for Whole-Breast Treatment in Prone Position." November 2015. Full Text
  - Lee, C-T, Zhou, Y, Siamakpour-Reihani, S, Choudhury, KR, Dewhirst, MW, and Horton, JK. "Abstract 3302: Subtype-specific radiation response in a mouse model of human breast cancer." : American Association for Cancer Research (AACR), August 1, 2015. Full Text
  - Siamakpour-Reihani, S, Chen, W, Lee, C-T, Zhou, Y, Owzar, K, Chi, J-T, and Horton, JK. "Abstract 3331: Gene expression profiling after radiation in human breast cancer specimens and breast cancer cell lines." : American Association for Cancer Research (AACR), August 1, 2015. Full Text
  - Arya, R, Jones, LW, Blitzblau, RC, Palta, M, Massa, L, Broadwater, G, and Horton, JK. "Abstract P2-12-07: The association between exercise behavior and patient-reported outcomes in women with early breast cancer receiving locoregional radiation therapy." : American Association for Cancer Research (AACR), May 1, 2015. Full Text
  - Mowery, YM, Greenup, RA, Houck, K, Palta, M, Horton, JK, Hwang, E-SS, Sosa, JA, and Blitzblau, RC. "Abstract P1-15-10: Low utilization of hypofractionated radiotherapy for the treatment of early-stage breast cancer in the US." : American Association for Cancer Research (AACR), May 1, 2015. Full Text
  - Palta, M, Palta, P, Bhavsar, NA, Horton, JK, and Blitzblau, RC. "The use of adjuvant radiotherapy in elderly patients with early-stage breast cancer: changes in practice patterns after publication of Cancer and Leukemia Group B 9343." January 2015. Full Text
  - Horton, JK, Blitzblau, R, Yoo, S, Georgiade, G, Geradts, J, Baker, J, Chi, JA, Chang, Z, Palta, M, Siamakpour-Reihani, S, Groth, J, Chen, W, Broadwater, G, Barry, WT, Duffy, E, and Hwang, S. "Preoperative Partial Breast Radiation Therapy: One Year Outcomes and Radiation-Induced Changes in Gene Expression." : Elsevier BV, September 2014. Full Text
  - Wang, C, Horton, JK, Yin, F, and Chang, Z. "Early Stage Breast Cancer Radiation Treatment Assessment Using Diffusion Weighted MRI and Dynamic Contrast Enhanced MRI." : Elsevier BV, September 2014. Full Text
  - Yoo, S, Blitzblau, R, Yin, F, and Horton, JK. "Delivered Dose for Preoperative Single Fraction Partial Breast Radiation Therapy." : Elsevier BV, September 2014. Full Text
  - Horton, J, Blitzblau, R, Yoo, S, Georgiade, G, Geradts, J, Baker, J, Chang, Z, Broadwater, G, Barry, W, Duffy, E, and Hwang, E. "Abstract P5-14-04: Preoperative single-fraction partial breast radiotherapy – Initial results from a novel phase I dose-escalation protocol with exploration of radiation response biomarkers." December 15, 2013. Full Text
  - Horton, JK, Blitzblau, RC, Yoo, S, Georgiade, GS, Geradts, J, Baker, JA, Chang, Z, Duffy, E, and Hwang, ES. "Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1 Dose-Escalation Protocol and Exploration of Breast Cancer Radiation Response." : Elsevier BV, October 2013. Full Text
  - Yoo, S, Blitzblau, R, Yin, F, and Horton, JK. "Comparison of Preoperative Partial Breast Radiosurgery Treatment Techniques: 3D-CRT, Non-Coplanar IMRT, Coplanar IMRT, and VMAT." : Elsevier BV, October 2013. Full Text
  - Chang, Z, Yin, F, Yoo, S, and Horton, J. "SU‐E‐CAMPUS‐J‐04: Evaluating Radiation‐Induced Changes with Diffusion Weighted MRI and Dynamic Contrast Enhanced MRI in Patients with Early Stage Breast Cancer Treated with Stereotactic Body Radiotherapy: Initial Results." January 1, 2013. Full Text
  - Horton, JK, Fels, DR, Kung, H, Ashcraft, K, Dewhirst, MW, and Chi, JA. "Gene Expression Response to Ionizing Radiation in Luminal and Basal Breast Cancer Cell Lines." November 1, 2012. Full Text Link to Item
  - Shah, MM, Peppercorn, J, Lee, CN, Broadwater, G, and Horton, JK. "Impact of a Photograph-based Educational Tool on Patient Knowledge and Satisfaction Regarding Cosmetic Outcomes after Breast Conservation Therapy: A Pilot Study." 2010. Full Text Link to Item
  - Yoo, S, O'daniel, J, Horton, J, wu, Q, and Yin, F. "SU‐GG‐T‐583: Dosimetric Comparison of Anisotropic Analytical and Pencil Beam Convolution Algorithms in Breast Cancer Radiation Treatment Planning." January 1, 2010. Full Text
  - Palta, M, Yoo, S, and Horton, JK. "Feasibility of Preoperative Single Fraction Partial Breast Radiotherapy for Early Stage Breast Cancer." December 15, 2009. Link to Item
  - Horton, JK, Shaw, MM, Hubbs, J, Demirci, S, Patrone, M, Light, KL, Temple, K, and Marks, LB. "Treatment Volume and Toxicity Outcomes: The Duke Partial Breast Experience." 2009. Full Text Link to Item

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