Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.D., Wake Forest University 2001
• 

  Duke Appointment History

  • Associate Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2014 - 2018
  • Assistant Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2008 - 2014
• Research
• 

  Selected Grants

  • Preoperative Breast Radiotherapy: A Tool to Provide Individualized and Biologically-Based Radiation Therapy awarded by Gateway for Cancer Research 2015 - 2020
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Blitzblau, Rachel C., and Janet K. Horton. “First, Do No Harm..” International Journal of Radiation Oncology, Biology, Physics 103, no. 2 (February 2019): 295–96. https://doi.org/10.1016/j.ijrobp.2018.04.029.
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    • Natarajan, Brahma, Daphna Spiegel, Elizabeth M. Nichols, Steven Feigenberg, Rachel Blitzblau, Gloria Broadwater, Eileen A. Duffy, Jay A. Baker, and Janet K. Horton. “Findings on Surveillance Imaging After Preoperative Partial Breast Irradiation for Early Stage Breast Cancer..” International Journal of Radiation Oncology, Biology, Physics 102, no. 4 (November 2018): 1374–81. https://doi.org/10.1016/j.ijrobp.2018.05.059.
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    • Belkacemi, Yazid, Benjamin D. Smith, and Janet K. Horton. “Regional Nodal Irradiation in the Modern Era of Breast Cancer Management..” Int J Radiat Oncol Biol Phys 101, no. 2 (June 1, 2018): 241–43. https://doi.org/10.1016/j.ijrobp.2017.10.036.
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    • Jagsi, Reshma, Kent A. Griffith, Jennifer R. Bellon, Wendy A. Woodward, Janet K. Horton, Alice Ho, Felix Y. Feng, et al. “Concurrent Veliparib With Chest Wall and Nodal Radiotherapy in Patients With Inflammatory or Locoregionally Recurrent Breast Cancer: The TBCRC 024 Phase I Multicenter Study..” Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 36, no. 13 (May 2018): 1317–22. https://doi.org/10.1200/jco.2017.77.2665.
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    • Rahal, Omar M., Adam R. Wolfe, Pijus K. Mandal, Richard Larson, Sanda Tin, Cristina Jimenez, Dadong Zhang, et al. “Blocking Interleukin (IL)4- and IL13-Mediated Phosphorylation of STAT6 (Tyr641) Decreases M2 Polarization of Macrophages and Protects Against Macrophage-Mediated Radioresistance of Inflammatory Breast Cancer..” International Journal of Radiation Oncology, Biology, Physics 100, no. 4 (March 2018): 1034–43. https://doi.org/10.1016/j.ijrobp.2017.11.043.
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    • Ryser, Marc D., Janet K. Horton, and E Shelley Hwang. “How Low Can We Go-and Should We? Risk Reduction for Minimal-Volume DCIS..” Annals of Surgical Oncology 25, no. 2 (February 2018): 354–55. https://doi.org/10.1245/s10434-017-6128-4.
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    • Horton, Janet K., Reshma Jagsi, Wendy A. Woodward, and Alice Ho. “Breast Cancer Biology: Clinical Implications for Breast Radiation Therapy..” International Journal of Radiation Oncology, Biology, Physics 100, no. 1 (January 2018): 23–37. https://doi.org/10.1016/j.ijrobp.2017.08.025.
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    • Horton, Janet K. “Postmastectomy Conundrum..” International Journal of Radiation Oncology, Biology, Physics 98, no. 5 (August 2017). https://doi.org/10.1016/j.ijrobp.2017.04.013.
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    • Lee, Chen-Ting, Yingchun Zhou, Kingshuk Roy-Choudhury, Sharareh Siamakpour-Reihani, Kenneth Young, Peter Hoang, John P. Kirkpatrick, Jen-Tsan A. Chi, Mark W. Dewhirst, and Janet K. Horton. “Subtype-Specific Radiation Response and Therapeutic Effect of FAS Death Receptor Modulation in Human Breast Cancer..” Radiat Res 188, no. 2 (August 2017): 169–80. https://doi.org/10.1667/RR14664.1.
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    • Greenup, Rachel A., Rachel C. Blitzblau, Kevin L. Houck, Julie Ann Sosa, Janet Horton, Jeffrey M. Peppercorn, Alphonse G. Taghian, Barbara L. Smith, and E Shelley Hwang. “Cost Implications of an Evidence-Based Approach to Radiation Treatment After Lumpectomy for Early-Stage Breast Cancer..” Journal of Oncology Practice 13, no. 4 (April 2017): e283–90. https://doi.org/10.1200/JOP.2016.016683.
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    • Morrow, Monica, Kimberly J. Van Zee, Lawrence J. Solin, Nehmat Houssami, Mariana Chavez-MacGregor, Jay R. Harris, Janet Horton, et al. “Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma In Situ..” Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 34, no. 33 (November 2016): 4040–46. https://doi.org/10.1200/JCO.2016.68.3573.
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    • Morrow, Monica, Kimberly J. Van Zee, Lawrence J. Solin, Nehmat Houssami, Mariana Chavez-MacGregor, Jay R. Harris, Janet Horton, et al. “Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery with Whole-Breast Irradiation in Ductal Carcinoma In Situ..” Ann Surg Oncol 23, no. 12 (November 2016): 3801–10. https://doi.org/10.1245/s10434-016-5449-z.
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    • Sheng, Y., T. Li, S. Yoo, F. F. Yin, R. C. Blitzblau, J. K. Horton, M. Palta, C. A. Hahn, Y. Ge, and Q. R. Wu. “Development of an Ultra-Fast, High-Quality Whole-Breast Radiation Therapy Treatment Planning System..” International Journal of Radiation Oncology, Biology, Physics 96, no. 2S (October 2016). https://doi.org/10.1016/j.ijrobp.2016.06.566.
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    • Spiegel, D., P. K. Marcom, B. Peterson, J. Force, L. Howie, M. Palta, R. C. Blitzblau, and J. K. Horton. “Acute Toxicity in Patients With HER2-Positive Breast Cancer Treated With Adjuvant Radiation Therapy and Concurrent Trastuzumab and Pertuzumab..” International Journal of Radiation Oncology, Biology, Physics 96, no. 2S (October 2016): E9–10. https://doi.org/10.1016/j.ijrobp.2016.06.619.
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    • Wang, C., J. K. Horton, F. F. Yin, E. Subashi, and Z. Chang. “Early-Stage Breast Radiation Therapy Assessment Using Transcytolemmal Water Exchange Analysis of DCE-Magnetic Resonance Imaging: Initial Results..” International Journal of Radiation Oncology, Biology, Physics 96, no. 2S (October 2016). https://doi.org/10.1016/j.ijrobp.2016.06.2176.
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    • Wang, Chunhao, Janet K. Horton, Fang-Fang Yin, and Zheng Chang. “Assessment of Treatment Response With Diffusion-Weighted MRI and Dynamic Contrast-Enhanced MRI in Patients With Early-Stage Breast Cancer Treated With Single-Dose Preoperative Radiotherapy: Initial Results..” Technology in Cancer Research & Treatment 15, no. 5 (October 2016): 651–60. https://doi.org/10.1177/1533034615593191.
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    • Yoo, S., J. K. Horton, F. F. Yin, and R. C. Blitzblau. “Dosimetric Effect of the Breast Board and Couch Top for Whole-Breast Radiation Therapy in the Prone Position..” International Journal of Radiation Oncology, Biology, Physics 96, no. 2S (October 2016): E46–47. https://doi.org/10.1016/j.ijrobp.2016.06.710.
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    • Morrow, Monica, Kimberly J. Van Zee, Lawrence J. Solin, Nehmat Houssami, Mariana Chavez-MacGregor, Jay R. Harris, Janet Horton, et al. “Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma in Situ..” Practical Radiation Oncology 6, no. 5 (September 2016): 287–95. https://doi.org/10.1016/j.prro.2016.06.011.
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    • Horton, J. K. “Integration of a Radiosensitivity Molecular Signature into the Assessment of Local Recurrence Risk in Breast Cancer.” Breast Diseases 27, no. 1 (January 1, 2016): 76–77. https://doi.org/10.1016/j.breastdis.2016.01.021.
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    • Kent, Collin, Janet Horton, Rachel Blitzblau, and Bridget F. Koontz. “Whose Disease Will Recur After Mastectomy for Early Stage, Node-Negative Breast Cancer? A Systematic Review..” Clinical Breast Cancer 15, no. 6 (December 2015): 403–12. https://doi.org/10.1016/j.clbc.2015.06.008.
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    • Horton, Janet K., Sharareh Siamakpour-Reihani, Chen-Ting Lee, Ying Zhou, Wei Chen, Joseph Geradts, Diane R. Fels, et al. “FAS Death Receptor: A Breast Cancer Subtype-Specific Radiation Response Biomarker and Potential Therapeutic Target..” Radiat Res 184, no. 5 (November 2015): 456–69. https://doi.org/10.1667/RR14089.1.
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    • Siamakpour-Reihani, Sharareh, Kouros Owzar, Chen Jiang, Taylor Turner, Yiwen Deng, Sarah M. Bean, Janet K. Horton, et al. “Prognostic significance of differential expression of angiogenic genes in women with high-grade serous ovarian carcinoma..” Gynecol Oncol 139, no. 1 (October 2015): 23–29. https://doi.org/10.1016/j.ygyno.2015.08.001.
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    • Blitzblau, Rachel C., Ritu Arya, Sua Yoo, Jay A. Baker, Zheng Chang, Manisha Palta, Eileen Duffy, and Janet K. Horton. “A phase 1 trial of preoperative partial breast radiation therapy: Patient selection, target delineation, and dose delivery..” Practical Radiation Oncology 5, no. 5 (September 2015): e513–20. https://doi.org/10.1016/j.prro.2015.02.002.
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    • Horton, Janet K., Rachel C. Blitzblau, Sua Yoo, Joseph Geradts, Zheng Chang, Jay A. Baker, Gregory S. Georgiade, et al. “Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1, Dose-Escalation Protocol With Radiation Response Biomarkers..” Int J Radiat Oncol Biol Phys 92, no. 4 (July 15, 2015): 846–55. https://doi.org/10.1016/j.ijrobp.2015.03.007.
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    • Arya, Ritu, Sharareh Siamakpour-Reihani, Manisha Palta, Lisa Massa, Gloria Broadwater, Rachel C. Blitzblau, and Janet K. Horton. “Exercise behavior and patient-reported outcomes in women with early breast cancer receiving locoregional radiation therapy..” Practical Radiation Oncology 5, no. 4 (July 2015): e275–81. https://doi.org/10.1016/j.prro.2015.01.003.
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    • Siamakpour-Reihani, Sharareh, Kouros Owzar, Chen Jiang, Peter M. Scarbrough, Oana I. Craciunescu, Janet K. Horton, Holly K. Dressman, Kimberly L. Blackwell, and Mark W. Dewhirst. “Genomic profiling in locally advanced and inflammatory breast cancer and its link to DCE-MRI and overall survival..” Int J Hyperthermia 31, no. 4 (June 2015): 386–95. https://doi.org/10.3109/02656736.2015.1016557.
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    • Yoo, Sua, Rachel Blitzblau, Fang-Fang Yin, and Janet K. Horton. “Dosimetric comparison of preoperative single-fraction partial breast radiotherapy techniques: 3D CRT, noncoplanar IMRT, coplanar IMRT, and VMAT..” Journal of Applied Clinical Medical Physics 16, no. 1 (January 8, 2015). https://doi.org/10.1120/jacmp.v16i1.5126.
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    • Horton, J. K. “First results of the preoperative accelerated partial breast irradiation (PAPBI) trial.” Breast Diseases 26, no. 4 (January 1, 2015): 341–42. https://doi.org/10.1016/j.breastdis.2015.10.014.
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    • Horton, J. K., and J. R. Bellon. “Oncology scandquality of life and patient perspectives during breast radiation therapy.” International Journal of Radiation Oncology Biology Physics 91, no. 2 (January 1, 2015): 249–51. https://doi.org/10.1016/j.ijrobp.2014.08.007.
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    • McGuire, Kandace P., E Shelley Hwang, Alan Cantor, Mehra Golshan, Funda Meric-Bernstam, Janet K. Horton, Rita Nanda, et al. “Surgical patterns of care in patients with invasive breast cancer treated with neoadjuvant systemic therapy and breast magnetic resonance imaging: results of a secondary analysis of TBCRC 017..” Annals of Surgical Oncology 22, no. 1 (January 2015): 75–81. https://doi.org/10.1245/s10434-014-3948-3.
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    • Palta, M., P. Palta, N. A. Bhavsar, J. K. Horton, and R. C. Blitzblau. “The use of adjuvant radiotherapy in elderly patients with early-stage breast cancer: Changes in practice patterns after publication of Cancer and Leukemia Group B 9343.” Cancer 121, no. 2 (January 1, 2015): 188–93. https://doi.org/10.1002/cncr.28937.
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    • Siamakpour-Reihani, S., K. Owzar, C. Jiang, T. Turner, Y. Deng, S. M. Bean, J. K. Horton, et al. “Prognostic significance of differential expression of angiogenic genes in women with high-grade serous ovarian carcinoma.” Gynecologic Oncology 139, no. 1 (2015): 23–29. https://doi.org/10.1016/j.ygyno.2015.08.001.
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    • Yoo, S., R. Blitzblau, F. F. Yin, and J. K. Horton. “Dosimetric comparison of preoperative single-fraction partial breast radiotherapy techniques: 3D CRT, noncoplanar IMRT, coplanar IMRT, and VMAT.” Journal of Applied Clinical Medical Physics 16, no. 1 (January 1, 2015): 183–91.
    • Horton, Janet K., Mark W. Dewhirst, Sharareh Siamakpour-Reihani, Yingchun Zhou, Joseph Geradts, Jen-Tsan Ashley Chi, and Wei Chen. “Changes in Gene Expression After Radiation in Human Breast Cancers: A Guide to Predicting and Modulating Radiation Response.” Journal of Womens Health 23, no. 10 (October 1, 2014): 861–861.
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    • Moran, M. S., S. J. Schnitt, A. E. Giuliano, J. R. Harris, S. A. Khan, J. Horton, S. Klimberg, et al. “Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer.” Journal of Clinical Oncology 32, no. 14 (May 10, 2014): 1507–15. https://doi.org/10.1200/JCO.2013.53.3935.
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    • Moran, Meena S., Stuart J. Schnitt, Armando E. Giuliano, Jay R. Harris, Seema A. Khan, Janet Horton, Suzanne Klimberg, et al. “Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer..” J Clin Oncol 32, no. 14 (May 10, 2014): 1507–15. https://doi.org/10.1200/JCO.2013.53.3935.
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    • Horton, J. K. “Prospective multicenter trial evaluating balloon-catheter partial-breast irradiation for ductal carcinoma in situ.” Breast Diseases 25, no. 1 (March 17, 2014): 80–81. https://doi.org/10.1016/j.breastdis.2014.01.015.
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    • Moran, Meena S., Stuart J. Schnitt, Armando E. Giuliano, Jay R. Harris, Seema A. Khan, Janet Horton, Suzanne Klimberg, et al. “Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer..” Int J Radiat Oncol Biol Phys 88, no. 3 (March 1, 2014): 553–64. https://doi.org/10.1016/j.ijrobp.2013.11.012.
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    • Moran, Meena S., Stuart J. Schnitt, Armando E. Giuliano, Jay R. Harris, Seema A. Khan, Janet Horton, Suzanne Klimberg, et al. “Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer..” Annals of Surgical Oncology 21, no. 3 (March 2014): 704–16. https://doi.org/10.1245/s10434-014-3481-4.
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    • Qiu, Jian-Jian, Zheng Chang, Janet K. Horton, Qing-Rong Jackie Wu, Sua Yoo, and Fang-Fang Yin. “Dosimetric comparison of 3D conformal, IMRT, and V-MAT techniques for accelerated partial-breast irradiation (APBI)..” Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists 39, no. 2 (January 27, 2014): 152–58. https://doi.org/10.1016/j.meddos.2013.12.001.
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    • Horton, J. K. “Effect of local therapy on locoregional recurrence in postmenopausal women with breast cancer in the Tamoxifen Exemestane Adjuvant Multinational (TEAM) trial: Van Hezewijk M, Bastiaannet E, Putter H, et al (Leiden Univ Med Ctr, the Netherlands; Et al) Radiother Oncol 108:190-196, 2013.” Breast Diseases 25, no. 2 (January 1, 2014): 179–80. https://doi.org/10.1016/j.breastdis.2014.04.037.
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    • McGuire, K. P., E. S. Hwang, A. Cantor, M. Golshan, F. Meric-Bernstam, J. K. Horton, R. Nanda, et al. “Surgical Patterns of Care in Patients with Invasive Breast Cancer Treated with Neoadjuvant Systemic Therapy and Breast Magnetic Resonance Imaging: Results of a Secondary Analysis of TBCRC 017.” Annals of Surgical Oncology 22, no. 1 (2014): 75–81. https://doi.org/10.1245/s10434-014-3948-3.
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    • Moran, M. S., S. J. Schnitt, A. E. Giuliano, J. R. Harris, S. A. Khan, J. Horton, S. Klimberg, et al. “Society of surgical oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages i and II invasive breast cancer.” Annals of Surgical Oncology 21, no. 3 (2014): 704–16.
    • Qiu, J. J., Z. Chang, J. K. Horton, Q. R. J. Wu, S. Yoo, and F. F. Yin. “Dosimetric comparison of 3D conformal, IMRT, and V-MAT techniques for accelerated partial-breast irradiation (APBI).” Medical Dosimetry 39, no. 2 (January 1, 2014): 152–58. https://doi.org/10.1016/j.meddos.2013.12.001.
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    • Blitzblau, Rachel C., and Janet K. Horton. “Treatment planning technique in patients receiving postmastectomy radiation therapy..” Practical Radiation Oncology 3, no. 4 (October 2013): 241–48. https://doi.org/10.1016/j.prro.2012.09.004.
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    • Horton, Janet K., Jen-Tsan Ashley Chi, Jeff Groth, Yingchun Zhou, Chen-Ting Lee, and Joseph Geradts. “Up-regulation of Fas Expression in Human Breast Carcinomas Treated With Preoperative Radiation.” Journal of Womens Health 22, no. 10 (October 1, 2013): 890–890.
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    • Blitzblau, Rachel C., and Janet K. Horton. “Radiotherapy after mastectomy..” Surgical Oncology Clinics of North America 22, no. 3 (July 2013): 563–77. https://doi.org/10.1016/j.soc.2013.02.012.
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    • De Los Santos, Jennifer F., Alan Cantor, Keith D. Amos, Andres Forero, Mehra Golshan, Janet K. Horton, Clifford A. Hudis, et al. “Magnetic resonance imaging as a predictor of pathologic response in patients treated with neoadjuvant systemic treatment for operable breast cancer. Translational Breast Cancer Research Consortium trial 017..” Cancer 119, no. 10 (May 2013): 1776–83. https://doi.org/10.1002/cncr.27995.
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    • Horton, J. K., and R. Jagsi. “Oncology scan - Breast cancers.” International Journal of Radiation Oncology Biology Physics 85, no. 5 (April 1, 2013): 1151–52. https://doi.org/10.1016/j.ijrobp.2013.01.007.
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    • Lyman, Gary H., Jay Baker, Joseph Geradts, Janet Horton, Gretchen Kimmick, Jeffrey Peppercorn, Scott Pruitt, Randall P. Scheri, and E Shelley Hwang. “Multidisciplinary care of patients with early-stage breast cancer..” Surgical Oncology Clinics of North America 22, no. 2 (April 2013): 299–317. https://doi.org/10.1016/j.soc.2012.12.005.
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    • Blitzblau, R. C., and J. K. Horton. “Radiotherapy After Mastectomy.” Surgical Oncology Clinics of North America 22, no. 3 (2013): 563–77. https://doi.org/10.1016/j.soc.2013.02.012.
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    • Blitzblau, R. C., and J. K. Horton. “Treatment planning technique in patients receiving postmastectomy radiation therapy.” Practical Radiation Oncology 3, no. 4 (2013): 241–48. https://doi.org/10.1016/j.prro.2012.09.004.
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    • Santos, J. F. D. L., A. Cantor, K. D. Amos, A. Forero, M. Golshan, J. K. Horton, C. A. Hudis, et al. “Magnetic resonance imaging as a predictor of pathologic response in patients treated with neoadjuvant systemic treatment for operable breast cancer: Translational Breast Cancer Research Consortium trial 017.” Cancer 119, no. 10 (2013): 1776–83. https://doi.org/10.1002/cncr.27995.
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    • Horton, Janet K., Diane R. Fels, Hsiu-Ni Kung, Yingchun Zhou, Kathleen Ashcraft, Mark W. Dewhirst, and Jen-Tsan Ashley Chi. “Differential Activation of Cell Death Pathways After Ionizing Radiation in Luminal and Basal Breast Cancer Cell Lines.” Journal of Womens Health 21, no. 10 (October 1, 2012): 992–992.
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    • Cuneo, Kyle C., Rajesh C. Dash, Lee G. Wilke, Janet K. Horton, and Bridget F. Koontz. “Risk of invasive breast cancer and ductal carcinoma in situ in women with atypical papillary lesions of the breast..” The Breast Journal 18, no. 5 (September 2012): 475–78. https://doi.org/10.1111/j.1524-4741.2012.01276.x.
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    • Moran, Meena S., and Janet K. Horton. “Oncology Scan – Breast Cancer.” International Journal of Radiation Oncology*Biology*Physics 84, no. 1 (September 2012): 1–3. https://doi.org/10.1016/s0360-3016(12)00929-7.
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    • Yoo, Sua, Qiuwen Wu, Jennifer O’Daniel, Janet Horton, and Fang-Fang Yin. “Comparison of 3D conformal breast radiation treatment plans using the anisotropic analytical algorithm and pencil beam convolution algorithm..” Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology 103, no. 2 (May 2012): 172–77. https://doi.org/10.1016/j.radonc.2012.01.010.
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    • Blitzblau, R. C., and J. K. Horton. “Evaluation of single nucleotide polymorphisms (SNPs) in the p53 binding protein 1 (TP53BP1) gene in breast cancer patients treated with breast-conserving surgery and whole-breast irradiation (BCS + RT).” Breast Diseases 23, no. 1 (March 7, 2012): 44–45. https://doi.org/10.1016/j.breastdis.2012.01.001.
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    • Betof, A. S., Z. N. Rabbani, M. E. Hardee, S. J. Kim, G. Broadwater, R. C. Bentley, S. A. Snyder, et al. “Carbonic anhydrase IX is a predictive marker of doxorubicin resistance in early-stage breast cancer independent of HER2 and TOP2A amplification..” Br J Cancer 106, no. 5 (February 28, 2012): 916–22. https://doi.org/10.1038/bjc.2012.32.
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    • Kimple, Randall J., Janet K. Horton, Chad A. Livasy, Janiel M. Shields, Julia A. Lawrence, Wingkeung M. Chiu, Anastasia Ivanova, et al. “Phase I study and biomarker analysis of lapatinib and concurrent radiation for locally advanced breast cancer..” The Oncologist 17, no. 12 (January 2012): 1496–1503. https://doi.org/10.1634/theoncologist.2012-0256.
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    • Palta, Manisha, Sua Yoo, Justus D. Adamson, Leonard R. Prosnitz, and Janet K. Horton. “Preoperative single fraction partial breast radiotherapy for early-stage breast cancer..” International Journal of Radiation Oncology, Biology, Physics 82, no. 1 (January 2012): 37–42. https://doi.org/10.1016/j.ijrobp.2010.09.041.
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    • Horton, J. K., D. R. Fels, J. A. Chi, H. Kung, J. P. Kirkpatrick, and M. Dewhirst. “Protein Pathway Activation after Ionizing Radiation in Luminal and Basal Breast Cancer Cell Lines.” International Journal of Radiation Oncology*Biology*Physics 81, no. 2 (October 2011): S160–61. https://doi.org/10.1016/j.ijrobp.2011.06.1658.
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    • Horton, Janet K., Diane R. Fels, Hsiu-Ni Kung, Mark W. Dewhirst, and Jen-Tsan Ashley Chi. “Gene Expression Response of Luminal and Basal Breast Cancer Cell Lines to Ionizing Radiation.” Journal of Womens Health 20, no. 10 (October 1, 2011): 1404–5.
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    • Horton, Janet K., John F. Gleason, Heidi D. Klepin, Scott Isom, Daniel B. Fried, and Ann M. Geiger. “Age-related disparities in the use of radiotherapy for treatment of localized soft tissue sarcoma..” Cancer 117, no. 17 (September 2011): 4033–40. https://doi.org/10.1002/cncr.25996.
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    • Horton, J. K. “Five-year analysis of treatment efficacy and cosmesis by the American Society of Breast Surgeons MammoSite breast brachytherapy registry trial in patients treated with accelerated partial breast irradiation.” Breast Diseases 22, no. 3 (August 30, 2011): 299–300. https://doi.org/10.1016/j.breastdis.2011.06.040.
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    • Palta, M., and J. K. Horton. “In response to Drs. Kim and Shaitelman.” International Journal of Radiation Oncology Biology Physics 80, no. 1 (May 1, 2011). https://doi.org/10.1016/j.ijrobp.2010.12.036.
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    • Shah, Mira M., Janet K. Horton, Sua Yoo, Jessica L. Hubbs, Senem Demirci, Kim L. Light, Kathy Temple, Michael Patrone, and Lawrence B. Marks. “A comparison of clinical and dosimetric outcomes in patients receiving partial breast irradiation with photon-only versus mixed photon/electron treatment plans..” Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists 36, no. 4 (January 2011): 423–28. https://doi.org/10.1016/j.meddos.2010.10.004.
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    • Qiu, Jian-Jian, Zheng Chang, Q Jackie Wu, Sua Yoo, Janet Horton, and Fang-Fang Yin. “Impact of volumetric modulated arc therapy technique on treatment with partial breast irradiation..” International Journal of Radiation Oncology, Biology, Physics 78, no. 1 (September 2010): 288–96. https://doi.org/10.1016/j.ijrobp.2009.10.036.
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    • Horton, Janet K., Jan Halle, Madlyn Ferraro, Lisa Carey, Dominic T. Moore, David Ollila, and Carolyn I. Sartor. “Radiosensitization of chemotherapy-refractory, locally advanced or locally recurrent breast cancer with trastuzumab: a phase II trial..” International Journal of Radiation Oncology, Biology, Physics 76, no. 4 (March 2010): 998–1004. https://doi.org/10.1016/j.ijrobp.2009.03.027.
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    • Godat, Laura N., Janet K. Horton, Perry Shen, John H. Stewart, Stacy Wentworth, and Edward A. Levine. “Recurrence after mastectomy for ductal carcinoma in situ..” The American Surgeon 75, no. 7 (July 2009): 592–95.
    • Prosnitz, Leonard R., Janet Horton, and Paul E. Wallner. “Accelerated partial breast irradiation: caution and concern from an ASTRO task force..” International Journal of Radiation Oncology, Biology, Physics 74, no. 4 (July 2009): 981–84. https://doi.org/10.1016/j.ijrobp.2009.03.046.
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    • Lally, Brian E., Ann M. Geiger, James J. Urbanic, Jerome M. Butler, Stacy Wentworth, Michael C. Perry, Lynn D. Wilson, et al. “Trends in the outcomes for patients with limited stage small cell lung cancer: An analysis of the Surveillance, Epidemiology, and End Results database..” Lung Cancer (Amsterdam, Netherlands) 64, no. 2 (May 2009): 226–31. https://doi.org/10.1016/j.lungcan.2008.08.010.
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    • Horton, Janet K., Jan S. Halle, Sha X. Chang, and Carolyn I. Sartor. “Comparison of three concomitant boost techniques for early-stage breast cancer..” International Journal of Radiation Oncology, Biology, Physics 64, no. 1 (January 2006): 168–75. https://doi.org/10.1016/j.ijrobp.2005.07.004.
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    • Horton, Janet K., and Joel E. Tepper. “Staging of colorectal cancer: past, present, and future..” Clinical Colorectal Cancer 4, no. 5 (January 2005): 302–12. https://doi.org/10.3816/ccc.2005.n.002.
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    • Horton, J. K. “Hospice. Care when there is no cure..” North Carolina Medical Journal 62, no. 2 (March 2001): 86–90.

  • Book Sections

    • Mowery, Y. M., C. X. Yu, and J. K. Horton. “Preoperative partial breast.” In Short Course Breast Radiotherapy: A Comprehensive Review of Hypofractionation, Partial Breast, and Intra-Operative Irradiation, 415–40, 2015. https://doi.org/10.1007/978-3-319-24388-7_27.
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  • Conference Papers

    • Sheng, Y., T. Li, S. Yoo, F. F. Yin, R. C. Blitzblau, Horton J. K. Sr, M. Palta, C. A. Hahn, Y. Ge, and Q. R. J. Wu. “Development of an Ultra-Fast, High-Quality Whole-Breast Radiation Therapy Treatment Planning System.” In International Journal of Radiation Oncology Biology Physics, 96:S228–S228, 2016. https://doi.org/10.1016/j.ijrobp.2016.06.566.
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    • Spiegel, D., K. Marcom, B. Peterson, J. Force, L. Howie, M. Palta, R. C. Blitzblau, and Horton J. K. Sr. “Acute Toxicity in Patients With HER2-Positive Breast Cancer Treated With Adjuvant Radiation Therapy and Concurrent Trastuzumab and Pertuzumab.” In International Journal of Radiation Oncology Biology Physics, 96:E9–10, 2016. https://doi.org/10.1016/j.ijrobp.2016.06.619.
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    • Wang, C., Horton J. K. Sr, F. F. Yin, E. Subashi, and Z. Chang. “Early-Stage Breast Radiation Therapy Assessment Using Transcytolemmal Water Exchange Analysis of DCE-Magnetic Resonance Imaging: Initial Results.” In International Journal of Radiation Oncology Biology Physics, 96:E617–E617, 2016. https://doi.org/10.1016/j.ijrobp.2016.06.2176.
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    • Yoo, S., Horton J. K. Sr, F. F. Yin, and R. C. Blitzblau. “Dosimetric Effect of the Breast Board and Couch Top for Whole-Breast Radiation Therapy in the Prone Position.” In International Journal of Radiation Oncology Biology Physics, 96:E46–47, 2016. https://doi.org/10.1016/j.ijrobp.2016.06.710.
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    • Adamson, J., Z. Chang, J. Cai, M. Palta, J. K. Horton, F. F. Yin, and R. Blitzblau. “Induction of Gradual Changes in Blood Oxygen Levels in Post Lumpectomy Breast Tissue With Breath Holding: Results of a Pilot Study.” In International Journal of Radiation Oncology*Biology*Physics, 93:E30–E30. Elsevier BV, 2015. https://doi.org/10.1016/j.ijrobp.2015.07.619.
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    • Horton, J. K., J. A. Baker, R. Blitzblau, G. S. Georgiade, E. S. Hwang, E. A. Duffy, M. Morgan, et al. “Preoperative Partial Breast Radiation Therapy: Short-term Imaging Outcomes With Two Unique Treatment Regimens.” In International Journal of Radiation Oncology*Biology*Physics, 93:E46–E46. Elsevier BV, 2015. https://doi.org/10.1016/j.ijrobp.2015.07.658.
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    • Jagsi, R., K. A. Griffith, J. R. Bellon, W. A. Woodward, J. K. Horton, A. Y. Ho, A. Schott, and L. J. Pierce. “TBCRC 024 Initial Results: A Multicenter Phase 1 Study of Veliparib Administered Concurrently With Chest Wall and Nodal Radiation Therapy in Patients With Inflammatory or Locoregionally Recurrent Breast Cancer.” In International Journal of Radiation Oncology*Biology*Physics, 93:S137–S137. Elsevier BV, 2015. https://doi.org/10.1016/j.ijrobp.2015.07.326.
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    • Nichols, E., S. J. Feigenberg, M. Morgan, W. Citron, S. Kesmodel, E. Bellavance, C. Drogula, et al. “Preoperative External Beam APBI: Report of Acute Toxicities From 2 Prospective Clinical Trials Using Two Different Fractionation Schemes.” In International Journal of Radiation Oncology*Biology*Physics, 93:E49–E49. Elsevier BV, 2015. https://doi.org/10.1016/j.ijrobp.2015.07.666.
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    • Wang, C., J. K. Horton, F. F. Yin, and Z. Chang. “Treatment Assessment Using Dynamic Fractal Signature Dissimilarity as a Novel Biomarker for Early-Stage Breast Cancer Radiation Therapy: A Feasibility Study.” In International Journal of Radiation Oncology*Biology*Physics, 93:S5–S5. Elsevier BV, 2015. https://doi.org/10.1016/j.ijrobp.2015.07.018.
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    • Yoo, S., J. K. Horton, F. F. Yin, and R. Blitzblau. “Dosimetric Effect of the Prone Breast Board and the Couch Top for Whole-Breast Treatment in Prone Position.” In International Journal of Radiation Oncology*Biology*Physics, 93:E610–E610. Elsevier BV, 2015. https://doi.org/10.1016/j.ijrobp.2015.07.2105.
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    • Lee, Chen-Ting, Yingchun Zhou, Sharareh Siamakpour-Reihani, Kingshuk R. Choudhury, Mark W. Dewhirst, and Janet K. Horton. “Abstract 3302: Subtype-specific radiation response in a mouse model of human breast cancer.” In Cancer Research, 75:3302–3302. American Association for Cancer Research (AACR), 2015. https://doi.org/10.1158/1538-7445.am2015-3302.
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    • Siamakpour-Reihani, Sharareh, Wei Chen, Chen-Ting Lee, Yingchun Zhou, Kouros Owzar, Jen-Tsan Chi, and Janet K. Horton. “Abstract 3331: Gene expression profiling after radiation in human breast cancer specimens and breast cancer cell lines.” In Cancer Research, 75:3331–3331. American Association for Cancer Research (AACR), 2015. https://doi.org/10.1158/1538-7445.am2015-3331.
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    • Arya, Ritu, Lee W. Jones, Rachel C. Blitzblau, Manisha Palta, Lisa Massa, Gloria Broadwater, and Janet K. Horton. “Abstract P2-12-07: The association between exercise behavior and patient-reported outcomes in women with early breast cancer receiving locoregional radiation therapy.” In Cancer Research, Vol. 75. American Association for Cancer Research (AACR), 2015. https://doi.org/10.1158/1538-7445.sabcs14-p2-12-07.
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    • Mowery, Yvonne M., Rachel A. Greenup, Kevin Houck, Manisha Palta, Janet K. Horton, Eun-Sil S. Hwang, Julie A. Sosa, and Rachel C. Blitzblau. “Abstract P1-15-10: Low utilization of hypofractionated radiotherapy for the treatment of early-stage breast cancer in the US.” In Cancer Research, Vol. 75. American Association for Cancer Research (AACR), 2015. https://doi.org/10.1158/1538-7445.sabcs14-p1-15-10.
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    • Palta, Manisha, Priya Palta, Nrupen A. Bhavsar, Janet K. Horton, and Rachel C. Blitzblau. “The use of adjuvant radiotherapy in elderly patients with early-stage breast cancer: changes in practice patterns after publication of Cancer and Leukemia Group B 9343..” In Cancer, 121:188–93, 2015. https://doi.org/10.1002/cncr.28937.
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    • Horton, J. K., R. Blitzblau, S. Yoo, G. Georgiade, J. Geradts, J. Baker, J. A. Chi, et al. “Preoperative Partial Breast Radiation Therapy: One Year Outcomes and Radiation-Induced Changes in Gene Expression.” In International Journal of Radiation Oncology*Biology*Physics, 90:S135–S135. Elsevier BV, 2014. https://doi.org/10.1016/j.ijrobp.2014.05.588.
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    • Wang, C., J. K. Horton, F. Yin, and Z. Chang. “Early Stage Breast Cancer Radiation Treatment Assessment Using Diffusion Weighted MRI and Dynamic Contrast Enhanced MRI.” In International Journal of Radiation Oncology*Biology*Physics, 90:S43–S43. Elsevier BV, 2014. https://doi.org/10.1016/j.ijrobp.2014.05.166.
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    • Yoo, S., R. Blitzblau, F. Yin, and J. K. Horton. “Delivered Dose for Preoperative Single Fraction Partial Breast Radiation Therapy.” In International Journal of Radiation Oncology*Biology*Physics, 90:S239–S239. Elsevier BV, 2014. https://doi.org/10.1016/j.ijrobp.2014.05.850.
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    • Horton, J. K., R. C. Blitzblau, S. Yoo, G. S. Georgiade, J. Geradts, J. A. Baker, Z. Chang, et al. “Abstract P5-14-04: Preoperative single-fraction partial breast radiotherapy – Initial results from a novel phase I dose-escalation protocol with exploration of radiation response biomarkers.” In Cancer Research, Vol. 73. American Association for Cancer Research (AACR), 2013. https://doi.org/10.1158/0008-5472.sabcs13-p5-14-04.
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    • Horton, J. K., R. C. Blitzblau, S. Yoo, G. S. Georgiade, J. Geradts, J. A. Baker, Z. Chang, E. Duffy, and E. S. Hwang. “Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1 Dose-Escalation Protocol and Exploration of Breast Cancer Radiation Response.” In International Journal of Radiation Oncology*Biology*Physics, 87:S229–S229. Elsevier BV, 2013. https://doi.org/10.1016/j.ijrobp.2013.06.594.
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    • Yoo, S., R. Blitzblau, F. Yin, and J. K. Horton. “Comparison of Preoperative Partial Breast Radiosurgery Treatment Techniques: 3D-CRT, Non-Coplanar IMRT, Coplanar IMRT, and VMAT.” In International Journal of Radiation Oncology*Biology*Physics, 87:S215–S215. Elsevier BV, 2013. https://doi.org/10.1016/j.ijrobp.2013.06.557.
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    • Chang, Z., F. Yin, S. Yoo, and J. Horton. “SU‐E‐CAMPUS‐J‐04: Evaluating Radiation‐Induced Changes with Diffusion Weighted MRI and Dynamic Contrast Enhanced MRI in Patients with Early Stage Breast Cancer Treated with Stereotactic Body Radiotherapy: Initial Results.” In Medical Physics, 40:378–79, 2013. https://doi.org/10.1118/1.4815176.
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    • Horton, J. K., D. R. Fels, H. Kung, K. Ashcraft, M. W. Dewhirst, and J. A. Chi. “Gene Expression Response to Ionizing Radiation in Luminal and Basal Breast Cancer Cell Lines.” In International Journal of Radiation Oncology*Biology*Physics, 84:S710–S710. Elsevier BV, 2012. https://doi.org/10.1016/j.ijrobp.2012.07.1900.
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    • Shah, M. M., J. Peppercorn, C. N. Lee, G. Broadwater, and J. K. Horton. “Impact of a Photograph-based Educational Tool on Patient Knowledge and Satisfaction Regarding Cosmetic Outcomes after Breast Conservation Therapy: A Pilot Study.” In International Journal of Radiation Oncology*Biology*Physics, 78:S232–33. Elsevier BV, 2010. https://doi.org/10.1016/j.ijrobp.2010.07.557.
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    • Yoo, S., J. O’daniel, J. Horton, Q. wu, and F. Yin. “SU‐GG‐T‐583: Dosimetric Comparison of Anisotropic Analytical and Pencil Beam Convolution Algorithms in Breast Cancer Radiation Treatment Planning.” In Medical Physics, Vol. 37, 2010. https://doi.org/10.1118/1.3468984.
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    • Palta, M., S. Yoo, and J. K. Horton. “Feasibility of Preoperative Single Fraction Partial Breast Radiotherapy for Early Stage Breast Cancer.” In Cancer Research, 69:741S-741S. AMER ASSOC CANCER RESEARCH, 2009.
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    • Horton, J. K., M. M. Shaw, J. Hubbs, S. Demirci, M. Patrone, K. L. Light, K. Temple, and L. B. Marks. “Treatment Volume and Toxicity Outcomes: The Duke Partial Breast Experience.” In International Journal of Radiation Oncology*Biology*Physics, 75:S207–8. Elsevier BV, 2009. https://doi.org/10.1016/j.ijrobp.2009.07.481.
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