Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., Duke University 2009
• 

  Previous Appointments & Affiliations

  • Instructor, Medical Center in the Department of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2013
• Expertise
• 

  Subject Headings

  • Big data
  • Computer Simulation
  • Genes, Recessive
  • Genetic Association Studies
  • Genetic Predisposition to Disease
  • High performance computing
  • Mathematical models
  • Virus Diseases
  • Virus-induced immunosuppression
• Research
• 

  Selected Grants

  • Training Program in Bioinformatics at the Intersection of Cancer Immunology and Microbiome awarded by National Institutes of Health 2020 - 2025
  • Quantitative Methods for HIV/AIDS Research awarded by National Institutes of Health 2018 - 2023
  • Impact of immune-based intervention on viral rebound in orally SHIV infected infant monkeys : Statistical Core awarded by Weill Cornell Medicine 2020 - 2022
  • A hands-on, integrative next-generation sequencing course: design, experiment, and analysis awarded by National Institutes of Health 2016 - 2020
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Zhang, Mengqi, Sahar Gelfman, Cristiane Araujo Martins Moreno, Janice M. McCarthy, Matthew B. Harms, David B. Goldstein, and Andrew S. Allen. “Focused goodness of fit tests for gene set analyses.” Brief Bioinform 23, no. 1 (January 17, 2022). https://doi.org/10.1093/bib/bbab472.
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    • Zhang, Mengqi, Sahar Gelfman, Janice McCarthy, Matthew B. Harms, Cristiane A. M. Moreno, David B. Goldstein, and Andrew S. Allen. “Incorporating external information to improve sparse signal detection in rare-variant gene-set-based analyses.” Genet Epidemiol 44, no. 4 (June 2020): 330–38. https://doi.org/10.1002/gepi.22283.
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    • Iversen, Edwin S., Janice M. McCarthy, Kirsten Bell Burdett, Gary Lipton, Gary Phillips, Holly Dressman, Joel Ross, and Nelson Chao. “Bridging the gaps: using an NHP model to predict single dose radiation absorption in humans.” Int J Radiat Biol 96, no. 1 (January 2020): 47–56. https://doi.org/10.1080/09553002.2018.1532614.
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    • Li, Zhiguo, Jiaxing Lin, Alexander B. Sibley, Tracy Truong, Katherina C. Chua, Yu Jiang, Janice McCarthy, Deanna L. Kroetz, Andrew Allen, and Kouros Owzar. “Efficient estimation of grouped survival models.” Bmc Bioinformatics 20, no. 1 (May 28, 2019): 269. https://doi.org/10.1186/s12859-019-2899-x.
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    • Xing, Chuanhua, Janice M McCarthy, Josée Dupuis, L. Adrienne Cupples, James B Meigs, Xihong Lin, and Andrew S Allen. “Robust analysis of secondary phenotypes in case-control genetic association studies.” Stat Med 35, no. 23 (October 15, 2016): 4226–37. https://doi.org/10.1002/sim.6976.
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    • Acharya, Chaitanya R., Janice M. McCarthy, Kouros Owzar, and Andrew S. Allen. “Exploiting expression patterns across multiple tissues to map expression quantitative trait loci.” Bmc Bioinformatics 17 (June 24, 2016): 257. https://doi.org/10.1186/s12859-016-1123-5.
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    • Mccarthy, Janice M., Patrick R. Shea, David B. Goldstein, and Andrew S. Allen. “Testing for risk and protective trends in genetic analyses of HIV acquisition.” Biostatistics 16, no. 2 (April 2015): 268–80. https://doi.org/10.1093/biostatistics/kxu044.
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    • Jiang, Yu, Janice M. McCarthy, and Andrew S. Allen. “Testing the effect of rare compound-heterozygous and recessive mutations in case--parent sequencing studies.” Genet Epidemiol 39, no. 3 (March 2015): 166–72. https://doi.org/10.1002/gepi.21885.
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• Teaching & Mentoring
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  Recent Courses

  • BIOSTAT 701: Introduction to Statistical Theory and Methods I 2021
  • BIOSTAT 701: Introduction to Statistical Theory and Methods I 2020
  • BIOSTAT 822: Data Science With R 2020
• Scholarly, Clinical, & Service Activities
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  Service to Duke

  • Academic Adviser. 2017 - 2019  2017 - 2019

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