Overview
My research is focused on mathematical modeling of the dynamics of biological systems using systems of ordinary differential equations, and calibrating those equations to data. Specifically, I am interested in two distinct areas of application: within host viral/immune system modeling and models of complex antibody-antigen binding kinetics.
I believe strongly that the future direction of biomedical research is in team science. My inter-disciplinary training has provided me with the skills to communicate effectively with both biologists and mathematicians, creating a bridge that helps to unite the team and move projects forward.
I believe strongly that the future direction of biomedical research is in team science. My inter-disciplinary training has provided me with the skills to communicate effectively with both biologists and mathematicians, creating a bridge that helps to unite the team and move projects forward.
Current Duke Appointments & Affiliations
Medical Instructor in Biostatistics & Bioinformatics
·
2019 - Present
Biostatistics & Bioinformatics, Division of Integrative Genomics,
Biostatistics & Bioinformatics
Recent Scholarly Works
htrSPRanalysis: An open source R package for expedited analysis of high-throughput binding kinetics data.
Journal article PLoS Comput Biol · July 2026 Surface plasmon resonance (SPR) enables label-free detection of binding kinetics and has been widely applied to the biophysical characterization of molecular interactions such as antibody-antigen binding. With the advent of high-throughput SPR (HT-SPR) ins ... Full text Link to item CiteSocial determinants of HIV status and viral load suppression among transgender women in South Africa: a cross-sectional analysis.
Journal article AIDS Care · September 2025 Transgender women in South Africa face a heavy HIV burden, but data on key psychosocial and structural factors remain limited. This cross-sectional study examined associations between HIV outcomes and psychosocial (substance use, alcohol use, medical distr ... Full text Open Access Link to item CiteModeling BK Virus Infection in Renal Transplant Recipients.
Journal article Viruses · December 31, 2024 Kidney transplant recipients require a lifelong protocol of immunosuppressive therapy to prevent graft rejection. However, these same medications leave them susceptible to opportunistic infections. One pathogen of particular concern is human polyomavirus 1 ... Full text Open Access Link to item CiteRecent Grants
Multiscale Modeling of Influenza Neutralizing Antibody and Fc Effector Biology
ResearchClinical Instructor · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029Quantitative Methods for HIV/AIDS Research
ResearchTraining Faculty · Awarded by National Institute of Allergy and Infectious Diseases · 2018 - 2028Training Program in Bioinformatics at the Intersection of Cancer Immunology and Microbiome
ResearchTraining Faculty · Awarded by National Cancer Institute · 2020 - 2026View All Grants
Education
Duke University ·
2009
Ph.D.