Overview
Current Appointments & Affiliations
Associate Professor of Pediatrics
·
2021 - Present
Pediatrics, Rheumatology,
Pediatrics
Recent Publications
Discovery of tissue-specific proteomic signatures in juvenile dermatomyositis highlights pathways reflecting persistent disease activity, clinical heterogeneity, and myositis-specific autoantibody subtype.
Journal Article Ann Rheum Dis · November 2025 OBJECTIVES: Juvenile dermatomyositis (JDM) is a heterogeneous autoimmune condition needing targeted treatment approaches and improved understanding of molecular mechanisms driving clinical phenotypes. We utilised exploratory proteomics from a longitudinal ... Full text Link to item CiteUnmasking inflammation in juvenile dermatomyositis: myokine profiles of patients and bioengineered human muscle.
Journal Article Front Immunol · 2025 INTRODUCTION: Juvenile dermatomyositis (JDM), a rare autoimmune disease characterized by a type I interferon (IFN) gene signature and muscle weakness, lacks robust biomarkers and disease models. Myokines-muscle-derived cytokines-are potential biomarkers an ... Full text Link to item CiteGenetic changes from type I interferons and JAK inhibitors: clues to drivers of juvenile dermatomyositis.
Journal Article Rheumatology (Oxford) · September 1, 2024 OBJECTIVE: To better understand the pathogenesis of juvenile dermatomyositis (JDM), we examined the effect of the cytokines type I interferons (IFN I) and JAK inhibitor drugs (JAKi) on gene expression in bioengineered pediatric skeletal muscle. METHODS: My ... Full text Link to item CiteRecent Grants
Using Bioengineered Human Muscle to Develop Treatments for Juvenile Dermatomyositis
ResearchCollaborator · Awarded by Hartwell Foundation · 2025 - 2028Pediatrics Juvenile Myositis program support
ResearchPrincipal Investigator · Awarded by Cure JM Foundation · 2019 - 2026Toward precision medicine for Juvenile Dermatomyositis: Development of a cross-tissue single-cell atlas
ResearchPrincipal Investigator · Awarded by University of Michigan · 2022 - 2026View All Grants
Education, Training & Certifications
University of Minnesota, Twin Cities ·
1993
M.D.