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Jeffrey Arthur Dvergsten

Professor of Pediatrics
Pediatrics, Rheumatology

Overview


Disease pathogenesis particularly in JIA, JDM and systemic-onset JIA.

Current Appointments & Affiliations


Professor of Pediatrics · 2026 - Present Pediatrics, Rheumatology, Pediatrics

Recent Publications


Autologous stem cell transplant for severe, progressive juvenile systemic sclerosis.

Journal Article Stem Cells Transl Med · March 23, 2026 Juvenile systemic sclerosis (jSSc) is a rare, chronic, autoimmune disease in children/adolescents and is associated with significant morbidity, skin thickening/hardening (scleroderma), organ toxicity and sub-optimal therapeutic options. In this report, aut ... Full text Link to item Cite

Discovery of tissue-specific proteomic signatures in juvenile dermatomyositis highlights pathways reflecting persistent disease activity, clinical heterogeneity, and myositis-specific autoantibody subtype.

Journal Article Ann Rheum Dis · November 2025 OBJECTIVES: Juvenile dermatomyositis (JDM) is a heterogeneous autoimmune condition needing targeted treatment approaches and improved understanding of molecular mechanisms driving clinical phenotypes. We utilised exploratory proteomics from a longitudinal ... Full text Link to item Cite

Unmasking inflammation in juvenile dermatomyositis: myokine profiles of patients and bioengineered human muscle.

Journal Article Front Immunol · 2025 INTRODUCTION: Juvenile dermatomyositis (JDM), a rare autoimmune disease characterized by a type I interferon (IFN) gene signature and muscle weakness, lacks robust biomarkers and disease models. Myokines-muscle-derived cytokines-are potential biomarkers an ... Full text Open Access Link to item Cite
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Recent Grants


Using Bioengineered Human Muscle to Develop Treatments for Juvenile Dermatomyositis

ResearchCollaborator · Awarded by Hartwell Foundation · 2025 - 2028

Pediatrics Juvenile Myositis program support

ResearchPrincipal Investigator · Awarded by Cure JM Foundation · 2019 - 2026

Toward precision medicine for Juvenile Dermatomyositis: Development of a cross-tissue single-cell atlas

ResearchPrincipal Investigator · Awarded by University of Michigan · 2022 - 2026

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Education


University of Minnesota, Twin Cities · 1993 M.D.