Jeffrey Ira Everitt | Scholars@Duke

Jeffrey Ira Everitt
Professor Track - V in Pathology

Current Appointments & Affiliations

Professor Track - V in Pathology, Pathology, Clinical Science Departments 2016
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2017

Contact Information

jeffrey.everitt@duke.edu

Background
Education, Training, & Certifications
- Adjunct Professor of Pathology, College of Veterinary Medicine,, Department Of Pathology, North Carolina State University 2010 - 2015
- D.V.M., Cornell University 1977
Duke Appointment History
- Adjunct Professor in the Department of Pathology, Pathology, Clinical Science Departments 2015 - 2016
Research
Selected Grants
- Mitigators of Radiation-Induced Endovascular Injury: Targeting Tie2 and Thrombocytopenia awarded by National Institutes of Health 2017 - 2022
- Advanced Technologies for Reducing Decompression Obligation and Risk awarded by Creare, Inc. 2018 - 2020
- Empowering Duke's Precision Pathology Center with Quantitative Image Analysis to Support Discovery, Diagnostic Assay Development, and Immune Cell Monitoring awarded by North Carolina Biotechnology Center 2018 - 2019
Publications & Artistic Works
Selected Publications
- Journal Articles
  - Hu, F, Martin, H, Martinez, A, Everitt, J, Erkanli, A, Lee, WT, Dewhirst, M, and Ramanujam, N. "Distinct Angiogenic Changes during Carcinogenesis Defined by Novel Label-Free Dark-Field Imaging in a Hamster Cheek Pouch Model." Cancer research 77, no. 24 (December 2017): 7109-7119. Full Text
  - Kim, Y, Lee, H-M, Xiong, Y, Sciaky, N, Hulbert, SW, Cao, X, Everitt, JI, Jin, J, Roth, BL, and Jiang, Y-H. "Targeting the histone methyltransferase G9a activates imprinted genes and improves survival of a mouse model of Prader-Willi syndrome." Nature medicine 23, no. 2 (February 2017): 213-222. Full Text
  - Bradley, T, Yang, G, Ilkayeva, O, Holl, TM, Zhang, R, Zhang, J, Santra, S, Fox, CB, Reed, SG, Parks, R, Bowman, CM, Bouton-Verville, H, Sutherland, LL, Scearce, RM, Vandergrift, N, Kepler, TB, Moody, MA, Liao, H-X, Alam, SM, McLendon, R, Everitt, JI, Newgard, CB, Verkoczy, L, Kelsoe, G, and Haynes, BF. "HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism." Journal of immunology (Baltimore, Md. : 1950) 197, no. 12 (December 2016): 4663-4673. Full Text
  - Brønstad, A, Newcomer, CE, Decelle, T, Everitt, JI, Guillen, J, and Laber, K. "Current concepts of Harm-Benefit Analysis of Animal Experiments - Report from the AALAS-FELASA Working Group on Harm-Benefit Analysis - Part 1." Laboratory animals 50, no. 1 Suppl (June 2016): 1-20. (Review) Full Text
  - Laber, K, Newcomer, CE, Decelle, T, Everitt, JI, Guillen, J, and Brønstad, A. "Recommendations for Addressing Harm-Benefit Analysis and Implementation in Ethical Evaluation - Report from the AALAS-FELASA Working Group on Harm-Benefit Analysis - Part 2." Laboratory animals 50, no. 1 Suppl (June 2016): 21-42. (Review) Full Text
  - Scudamore, CL, Soilleux, EJ, Karp, NA, Smith, K, Poulsom, R, Herrington, CS, Day, MJ, Brayton, CF, Bolon, B, Whitelaw, B, White, ES, Everitt, JI, and Arends, MJ. "Recommendations for minimum information for publication of experimental pathology data: MINPEPA guidelines." The Journal of pathology 238, no. 2 (January 2016): 359-367. (Review) Full Text
  - Shen, Z, Feng, Y, Sheh, A, Everitt, J, Bertram, F, Paster, BJ, and Fox, JG. "Isolation and characterization of a novel Helicobacter species, Helicobacter jaachi sp. nov., from common marmosets (Callithrix jaachus)." Journal of medical microbiology 64, no. 9 (September 2015): 1063-1073. Full Text
  - Everitt, JI. "The future of preclinical animal models in pharmaceutical discovery and development: a need to bring in cerebro to the in vivo discussions." Toxicologic pathology 43, no. 1 (January 2015): 70-77. Full Text
  - Rose, M, Everitt, J, Hedrich, H, Schofield, J, Dennis, M, Scott, E, Griffin, G, and ICLAS Working Group on Harmonization, . "ICLAS Working Group on Harmonization: international guidance concerning the production care and use of genetically-altered animals." Laboratory animals 47, no. 3 (July 2013): 146-152. Full Text
  - Boyle, MC, Boyle, MH, and Sixth Rodent Pathology Course Committee, . "Meeting report: Urinary Pathology; sixth Research Triangle Park Rodent Pathology Course." Veterinary pathology 50, no. 3 (May 2013): 563-568. Full Text
  - Corlett, PR, Cambridge, V, Gardner, JM, Piggot, JS, Turner, DC, Everitt, JC, Arana, FS, Morgan, HL, Milton, AL, Lee, JL, Aitken, MRF, Dickinson, A, Everitt, BJ, Absalom, AR, Adapa, R, Subramanian, N, Taylor, JR, Krystal, JH, and Fletcher, PC. "Ketamine effects on memory reconsolidation favor a learning model of delusions." PloS one 8, no. 6 (January 2013): e65088-. Full Text
  - Greathouse, KL, Bredfeldt, T, Everitt, JI, Lin, K, Berry, T, Kannan, K, Mittelstadt, ML, Ho, S-M, and Walker, CL. "Environmental estrogens differentially engage the histone methyltransferase EZH2 to increase risk of uterine tumorigenesis." Molecular cancer research : MCR 10, no. 4 (April 2012): 546-557. Full Text
  - Broaddus, VC, Everitt, JI, Black, B, and Kane, AB. "Non-neoplastic and neoplastic pleural endpoints following fiber exposure." Journal of toxicology and environmental health. Part B, Critical reviews 14, no. 1-4 (January 2011): 153-178. (Review) Full Text
  - Workman, P, Aboagye, EO, Balkwill, F, Balmain, A, Bruder, G, Chaplin, DJ, Double, JA, Everitt, J, Farningham, DAH, Glennie, MJ, Kelland, LR, Robinson, V, Stratford, IJ, Tozer, GM, Watson, S, Wedge, SR, Eccles, SA, and Committee of the National Cancer Research Institute, . "Guidelines for the welfare and use of animals in cancer research." British journal of cancer 102, no. 11 (May 2010): 1555-1577. Full Text
  - Kirby, PJ, Shines, CJ, Taylor, GJ, Bousquet, RW, Price, HC, Everitt, JI, and Morgan, DL. "Pleural effects of indium phosphide in B6C3F1 mice: nonfibrous particulate induced pleural fibrosis." Experimental lung research 35, no. 10 (December 2009): 858-882. Full Text
  - Ryman-Rasmussen, JP, Cesta, MF, Brody, AR, Shipley-Phillips, JK, Everitt, JI, Tewksbury, EW, Moss, OR, Wong, BA, Dodd, DE, Andersen, ME, and Bonner, JC. "Inhaled carbon nanotubes reach the subpleural tissue in mice." Nature nanotechnology 4, no. 11 (November 2009): 747-751. Full Text
  - Lanzoni, A, Piaia, A, Everitt, J, Faustinelli, I, Defazio, R, Cavaliere, L, and Cristofori, P. "Early onset of spontaneous renal preneoplastic and neoplastic lesions in young conventional rats in toxicity studies." Toxicologic pathology 35, no. 4 (June 2007): 589-593. Full Text
  - Laping, NJ, Everitt, JI, Frazier, KS, Burgert, M, Portis, MJ, Cadacio, C, Gold, LI, and Walker, CL. "Tumor-specific efficacy of transforming growth factor-beta RI inhibition in Eker rats." Clinical cancer research : an official journal of the American Association for Cancer Research 13, no. 10 (May 2007): 3087-3099. Full Text
  - Mally, A, Walker, CL, Everitt, JI, Dekant, W, and Vamvakas, S. "Analysis of renal cell transformation following exposure to trichloroethene in vivo and its metabolite S-(dichlorovinyl)-L-cysteine in vitro." Toxicology 224, no. 1-2 (July 2006): 108-118. Full Text
  - Roberts, ES, Bonner, AM, Everitt, JI, and Dorman, DC. "What's your diagnosis? Lethargy and hind limb paralysis in a day-23 timed pregnant rat." Lab animal 35, no. 2 (February 2006): 19-20. Full Text
  - Everitt, JI, and Shapiro, SJ. "The art and science of introducing animals to the research environment." ILAR journal 47, no. 4 (January 2006): 281-282. Full Text
  - Schapiro, SA, and Everitt, JI. "Preparation of animals for use in the laboratory: issues and challenges for the Institutional Animal Care and Use Committee (IACUC)." ILAR journal 47, no. 4 (January 2006): 370-375. Full Text
  - Floyd, HS, Farnsworth, CL, Kock, ND, Mizesko, MC, Little, JL, Dance, ST, Everitt, J, Tichelaar, J, Whitsett, JA, and Miller, MS. "Conditional expression of the mutant Ki-rasG12C allele results in formation of benign lung adenomas: development of a novel mouse lung tumor model." Carcinogenesis 26, no. 12 (December 2005): 2196-2206. Full Text
  - Corton, JC, Apte, U, Anderson, SP, Limaye, P, Yoon, L, Latendresse, J, Dunn, C, Everitt, JI, Voss, KA, Swanson, C, Kimbrough, C, Wong, JS, Gill, SS, Chandraratna, RAS, Kwak, M-K, Kensler, TW, Stulnig, TM, Steffensen, KR, Gustafsson, J-A, and Mehendale, HM. "Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors." The Journal of biological chemistry 279, no. 44 (October 2004): 46204-46212. Full Text
  - Mangum, J, Bermudez, E, Sar, M, and Everitt, J. "Osteopontin expression in particle-induced lung disease." Experimental lung research 30, no. 7 (October 2004): 585-598. Full Text
  - Dong, J, Everitt, JI, Lau, SS, and Monks, TJ. "Induction of ERK1/2 and histone H3 phosphorylation within the outer stripe of the outer medulla of the Eker rat by 2,3,5-tris-(glutathion-S-yl)hydroquinone." Toxicological sciences : an official journal of the Society of Toxicology 80, no. 2 (August 2004): 350-357. Full Text
  - Dorman, DC, McManus, BE, Parkinson, CU, Manuel, CA, McElveen, AM, and Everitt, JI. "Nasal toxicity of manganese sulfate and manganese phosphate in young male rats following subchronic (13-week) inhalation exposure." Inhalation toxicology 16, no. 6-7 (June 2004): 481-488. Full Text
  - Gardner, SY, McGee, JK, Kodavanti, UP, Ledbetter, A, Everitt, JI, Winsett, DW, Doerfler, DL, and Costa, DL. "Emission-particle-induced ventilatory abnormalities in a rat model of pulmonary hypertension." Environmental health perspectives 112, no. 8 (June 2004): 872-878. Full Text
  - Kleymenova, E, Everitt, JI, Pluta, L, Portis, M, Gnarra, JR, and Walker, CL. "Susceptibility to vascular neoplasms but no increased susceptibility to renal carcinogenesis in Vhl knockout mice." Carcinogenesis 25, no. 3 (March 2004): 309-315. Full Text
  - Bermudez, E, Mangum, JB, Wong, BA, Asgharian, B, Hext, PM, Warheit, DB, and Everitt, JI. "Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles." Toxicological sciences : an official journal of the Society of Toxicology 77, no. 2 (February 2004): 347-357. Full Text
  - Everitt, JI, and Foster, PMD. "Laboratory animal science issues in the design and conduct of studies with endocrine-active compounds." ILAR journal 45, no. 4 (January 2004): 417-424. (Review) Full Text
  - Walker, CL, Hunter, D, and Everitt, JI. "Uterine leiomyoma in the Eker rat: a unique model for important diseases of women." Genes, chromosomes & cancer 38, no. 4 (December 2003): 349-356. (Review) Full Text
  - Faiola, B, Bauer, AK, Fuller, ES, Wong, VA, Pluta, LJ, Abernethy, DJ, Mangum, JB, Everitt, JI, and Recio, L. "Variations in Prkdc and susceptibility to benzene-induced toxicity in mice." Toxicological sciences : an official journal of the Society of Toxicology 75, no. 2 (October 2003): 321-332. Full Text
  - Bermudez, E, Mangum, JB, Moss, OR, Wong, BA, and Everitt, JI. "Pleural dosimetry and pathobiological responses in rats and hamsters exposed subchronically to MMVF 10a fiberglass." Toxicological sciences : an official journal of the Society of Toxicology 74, no. 1 (July 2003): 165-173. Full Text
  - Hill, GD, Mangum, JB, Moss, OR, and Everitt, JI. "Soluble ICAM-1, MCP-1, and MIP-2 protein secretion by rat pleural mesothelial cells following exposure to amosite asbestos." Experimental lung research 29, no. 5 (July 2003): 277-290. Full Text
  - Bauer, AK, Faiola, B, Abernethy, DJ, Marchan, R, Pluta, LJ, Wong, VA, Gonzalez, FJ, Butterworth, BE, Borghoff, SJ, Everitt, JI, and Recio, L. "Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity." Toxicological sciences : an official journal of the Society of Toxicology 72, no. 2 (April 2003): 201-209. Full Text
  - Lambert, AL, Mangum, JB, DeLorme, MP, and Everitt, JI. "Ultrafine carbon black particles enhance respiratory syncytial virus-induced airway reactivity, pulmonary inflammation, and chemokine expression." Toxicological sciences : an official journal of the Society of Toxicology 72, no. 2 (April 2003): 339-346. Full Text
  - Lambert, AL, Trasti, FS, Mangum, JB, and Everitt, JI. "Effect of preexposure to ultrafine carbon black on respiratory syncytial virus infection in mice." Toxicological sciences : an official journal of the Society of Toxicology 72, no. 2 (April 2003): 331-338. Full Text
  - Bauer, AK, Faiola, B, Abernethy, DJ, Marchan, R, Pluta, LJ, Wong, VA, Roberts, K, Jaiswal, AK, Gonzalez, FJ, Butterworth, BE, Borghoff, S, Parkinson, H, Everitt, J, and Recio, L. "Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1." Cancer research 63, no. 5 (March 2003): 929-935.
  - Cai, S, Everitt, JI, Kugo, H, Cook, J, Kleymenova, E, and Walker, CL. "Polycystic kidney disease as a result of loss of the tuberous sclerosis 2 tumor suppressor gene during development." The American journal of pathology 162, no. 2 (February 2003): 457-468. Full Text
  - Bermudez, E, Mangum, JB, Asgharian, B, Wong, BA, Reverdy, EE, Janszen, DB, Hext, PM, Warheit, DB, and Everitt, JI. "Long-term pulmonary responses of three laboratory rodent species to subchronic inhalation of pigmentary titanium dioxide particles." Toxicological sciences : an official journal of the Society of Toxicology 70, no. 1 (November 2002): 86-97. Full Text
  - Seely, JC, Haseman, JK, Nyska, A, Wolf, DC, Everitt, JI, and Hailey, JR. "The effect of chronic progressive nephropathy on the incidence of renal tubule cell neoplasms in control male F344 rats." Toxicologic pathology 30, no. 6 (November 2002): 681-686. Full Text
  - Yoon, H-S, Monks, TJ, Everitt, JI, Walker, CL, and Lau, SS. "Cell proliferation is insufficient, but loss of tuberin is necessary, for chemically induced nephrocarcinogenicity." American journal of physiology. Renal physiology 283, no. 2 (August 2002): F262-F270. Full Text
  - Constan, AA, Wong, BA, Everitt, JI, and Butterworth, BE. "Chloroform inhalation exposure conditions necessary to initiate liver toxicity in female B6C3F1 mice." Toxicological sciences : an official journal of the Society of Toxicology 66, no. 2 (April 2002): 201-208. Full Text
  - Hesterberg, TW, Hart, GA, Miiller, WC, Chase, G, Rogers, RA, Mangum, JB, and Everitt, JI. "Use of short-term assays to evaluate the potential toxicity of two new biosoluble glasswool fibers." Inhalation toxicology 14, no. 3 (March 2002): 217-246. Full Text
  - You, L, Casanova, M, Bartolucci, EJ, Fryczynski, MW, Dorman, DC, Everitt, JI, Gaido, KW, Ross, SM, and Heck Hd, HD. "Combined effects of dietary phytoestrogen and synthetic endocrine-active compound on reproductive development in Sprague-Dawley rats: genistein and methoxychlor." Toxicological sciences : an official journal of the Society of Toxicology 66, no. 1 (March 2002): 91-104. Full Text
  - Torti, VR, Cobb, AJ, Everitt, JI, Marshall, MW, Boorman, GA, and Butterworth, BE. "Nephrotoxicity and hepatotoxicity induced by inhaled bromodichloromethane in wild-type and p53-heterozygous mice." Toxicological sciences : an official journal of the Society of Toxicology 64, no. 2 (December 2001): 269-280. Full Text
  - Recio, L, and Everitt, J. "Use of genetically modified mouse models for evaluation of carcinogenic risk: considerations for the laboratory animal scientist." Comparative medicine 51, no. 5 (October 2001): 399-405. (Review)
  - Dye, JA, Lehmann, JR, McGee, JK, Winsett, DW, Ledbetter, AD, Everitt, JI, Ghio, AJ, and Costa, DL. "Acute pulmonary toxicity of particulate matter filter extracts in rats: coherence with epidemiologic studies in Utah Valley residents." Environmental health perspectives 109 Suppl 3 (June 2001): 395-403. Full Text
  - Dye, JA, Lehmann, JR, McGee, JK, Winsett, DW, Ledbetter, AD, Everitt, JI, Ghio, AJ, and Costa, DL. "Acute Pulmonary Toxicity of Particulate Matter Filter Extracts in Rats: Coherence with Epidemiologic Studies in Utah Valley Residents." Environmental Health Perspectives 109 (June 2001): 395-395. Full Text
  - Borghoff, SJ, Prescott, JS, Janszen, DB, Wong, BA, and Everitt, JI. "alpha 2u-Globulin nephropathy, renal cell proliferation, and dosimetry of inhaled tert-butyl alcohol in male and female F-344 rats." Toxicological sciences : an official journal of the Society of Toxicology 61, no. 1 (May 2001): 176-186. Full Text
  - Kleymenova, E, Ibraghimov-Beskrovnaya, O, Kugoh, H, Everitt, J, Xu, H, Kiguchi, K, Landes, G, Harris, P, and Walker, C. "Tuberin-Dependent Membrane Localization of Polycystin-1." Molecular Cell 7, no. 4 (April 2001): 823-832. Full Text
  - Kleymenova, E, Ibraghimov-Beskrovnaya, O, Kugoh, H, Everitt, J, Xu, H, Kiguchi, K, Landes, G, Harris, P, and Walker, C. "Tuberin-dependent membrane localization of polycystin-1: a functional link between polycystic kidney disease and the TSC2 tumor suppressor gene." Molecular cell 7, no. 4 (April 2001): 823-832. Full Text
  - Lau, SS, Monks, TJ, Everitt, JI, Kleymenova, E, and Walker, CL. "Carcinogenicity of a nephrotoxic metabolite of the "nongenotoxic" carcinogen hydroquinone." Chemical research in toxicology 14, no. 1 (January 2001): 25-33. Full Text
  - Lau, SS, Yoon, HS, Patel, SK, Everitt, JI, Walker, CL, and Monks, TJ. "Mutagenicity and carcinogenicity of biological reactive intermediate's derived from a "non-genotoxic" carcinogen." Advances in experimental medicine and biology 500 (January 2001): 83-92. (Review)
  - Newbold, RR, DiAugustine, RP, Risinger, JI, Everitt, JI, Walmer, DK, Parrott, EC, and Dixon, D. "Advances in Uterine Leiomyoma Research: Conference Overview, Summary, and Future Research Recommendations." Environmental Health Perspectives 108 (October 2000): 769-769. Full Text
  - Newbold, RR, DiAugustine, RP, Risinger, JI, Everitt, JI, Walmer, DK, Parrott, EC, and Dixon, D. "Advances in uterine leiomyoma research: conference overview, summary, and future research recommendations." Environmental health perspectives 108 Suppl 5 (October 2000): 769-773. (Review) Full Text
  - Wolf, DC, Goldsworthy, TL, Janszen, DB, Harden, R, Donner, EM, David, CS, and Everitt, JI. "Promotion by sodium barbital induces early development but does not increase the multiplicity of hereditary renal tumors in Eker rats." Carcinogenesis 21, no. 8 (August 2000): 1553-1558. Full Text
  - Walker, CL, Burroughs, KD, Davis, B, Sowell, K, Everitt, JI, and Fuchs-Young, R. "Preclinical evidence for therapeutic efficacy of selective estrogen receptor modulators for uterine leiomyoma." Journal of the Society for Gynecologic Investigation 7, no. 4 (July 2000): 249-256. Full Text
  - Everitt, JI, Mangum, JB, Bermudez, E, Wong, BA, Asgharian, B, Reverdy, EE, Hext, PM, and Warheit, DB. "Comparison of Selected Pulmonary Responses of Rats, Mice, and Syrian Golden Hamsters to Inhaled Pigmentary Titanium Dioxide." Inhalation toxicology 12 Suppl 3 (January 2000): 275-282. Full Text
  - Reverdy, EE, Bermudez, E, Mangum, JB, Asgharian, B, Wong, B, and Everitt, JI. "Protein Carbonyls in Bronchoalveolar Lavage Fluid in Mice, Rats and Hamsters Following Inhalation of Pigmentary Titanium Dioxide Particles." Inhalation toxicology 12 Suppl 3 (January 2000): 283-289. Full Text
  - Kleymenova, EV, Horesovsky, G, Pylev, LN, and Everitt, J. "Mesotheliomas induced in rats by the fibrous mineral erionite are independent from p53 alterations." Cancer letters 147, no. 1-2 (December 1999): 55-61. Full Text
  - Constan, AA, Sprankle, CS, Peters, JM, Kedderis, GL, Everitt, JI, Wong, BA, Gonzalez, FL, and Butterworth, BE. "Metabolism of chloroform by cytochrome P450 2E1 is required for induction of toxicity in the liver, kidney, and nose of male mice." Toxicology and applied pharmacology 160, no. 2 (October 1999): 120-126. Full Text
  - Hesterberg, TW, Axten, C, McConnell, EE, Hart, GA, Miiller, W, Chevalier, J, Everitt, J, Thevenaz, P, and Oberdörster, G. "Studies on the inhalation toxicology of two fiberglasses and amosite asbestos in the syrian golden hamster. Part I. Results of a subchronic study and dose selection for a chronic study." Inhalation toxicology 11, no. 9 (September 1999): 747-784. Full Text
  - McConnell, EE, Axten, C, Hesterberg, TW, Chevalier, J, Miiller, WC, Everitt, J, Oberdörster, G, Chase, GR, Thevenaz, P, and Kotin, P. "Studies on the inhalation toxicology of two fiberglasses and amosite asbestos in the Syrian golden hamster. Part II. Results of chronic exposure." Inhalation toxicology 11, no. 9 (September 1999): 785-835. Full Text
  - Gelzleichter, TR, Bermudez, E, Mangum, JB, Wong, BA, Janszen, DB, Moss, OR, and Everitt, JI. "Comparison of pulmonary and pleural responses of rats and hamsters to inhaled refractory ceramic fibers." Toxicological sciences : an official journal of the Society of Toxicology 49, no. 1 (May 1999): 93-101. Full Text
  - Everitt, J. "Experimental approaches for studies of particulate matter: the case for stronger consideration of dosimetric and exposure issues." Experimental lung research 24, no. 6 (November 1998): 705-707. (Review) Full Text
  - Wolf, DC, Goldsworthy, TL, Donner, EM, Harden, R, Fitzpatrick, B, and Everitt, JI. "Estrogen treatment enhances hereditary renal tumor development in Eker rats." Carcinogenesis 19, no. 11 (November 1998): 2043-2047. Full Text
  - Fowler, L, Everitt, J, Stevens, JL, and Jaken, S. "Redistribution and enhanced protein kinase C-mediated phosphorylation of alpha- and gamma-adducin during renal tumor progression." Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 9, no. 5 (May 1998): 405-413.
  - Butterworth, BE, Templin, MV, Constan, AA, Sprankle, CS, Wong, BA, Pluta, LJ, Everitt, JI, and Recio, L. "Long-term mutagenicity studies with chloroform and dimethylnitrosamine in female lacI transgenic B6C3F1 mice." Environmental and molecular mutagenesis 31, no. 3 (January 1998): 248-256. Full Text
  - Everitt, JI, Gelzleichter, TR, Bermudez, E, Mangum, JB, Wong, BA, Janszen, DB, and Moss, OR. "Comparison of pleural responses of rats and hamsters to subchronic inhalation of refractory ceramic fibers." Environmental health perspectives 105 Suppl 5 (September 1997): 1209-1213. Full Text
  - Everitt, JI, Gelzleichter, TR, Bermudez, E, Mangum, JB, Wong, BA, Janszen, DB, and Moss, OR. "Comparison of pleural responses of rats and hamsters to subchronic inhalation of refractory ceramic fibers." Environmental Health Perspectives 105, no. Suppl 5 (September 1, 1997): 1209-1213. Full Text
  - Hesterberg, TW, Axten, C, McConnell, EE, Oberdörster, G, Everitt, J, Miiller, WC, Chevalier, J, Chase, GR, and Thevenaz, P. "Chronic inhalation study of fiber glass and amosite asbestos in hamsters: twelve-month preliminary results." Environmental health perspectives 105 Suppl 5 (September 1997): 1223-1229. Full Text
  - King-Herbert, AP, Hesterburg, TW, Thevenaz, PP, Hamm, TE, Moss, OR, Janszen, DB, and Everitt, JI. "Effects of immobilization restraint on Syrian golden hamsters." Laboratory animal science 47, no. 4 (August 1997): 362-366.
  - Everitt, JI, Walker, CL, Goldsworthy, TW, and Wolf, DC. "Altered expression of transforming growth factor-α: An early event in renal cell carcinoma development." Molecular Carcinogenesis 19, no. 3 (July 1997): 213-219. Full Text
  - Everitt, JI, Walker, CL, Goldsworthy, TW, and Wolf, DC. "Altered expression of transforming growth factor-alpha: an early event in renal cell carcinoma development." Molecular carcinogenesis 19, no. 3 (July 1997): 213-219. Full Text
  - Medinsky, MA, Dorman, DC, Bond, JA, Moss, OR, Janszen, DB, and Everitt, JI. "Pharmacokinetics of methanol and formate in female cynomolgus monkeys exposed to methanol vapors." Research report (Health Effects Institute) , no. 77 (June 1997): 1-30.
  - Gardner, SY, Brody, AR, Mangum, JB, and Everitt, JI. "Chrysotile asbestos and H2O2 increase permeability of alveolar epithelium." Experimental lung research 23, no. 1 (January 1997): 1-16. Full Text
  - Howe, SR, Everitt, JL, Gottardis, MM, and Walker, C. "Rodent model of reproductive tract leiomyomata: characterization and use in preclinical therapeutic studies." Progress in clinical and biological research 396 (January 1997): 205-215. (Review)
  - Gelzleichter, TR, Mangum, JB, Bermudez, E, Wong, BA, Moss, OR, and Everitt, JI. "Pulmonary and pleural leukocytes from F344 rats produce elevated levels of fibronectin following inhalation of refractory ceramic fibers." Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 48, no. 6 (November 1996): 487-489. Full Text
  - Hesterberg, TW, McConnel, EE, Miiller, WC, Chevalier, J, Everitt, J, Thevenaz, P, Fleissner, H, and Oberdörster, G. "Use of lung toxicity and lung particle clearance to estimate the maximum tolerated dose (MTD) for a fiber glass chronic inhalation study in the rat." Fundamental and applied toxicology : official journal of the Society of Toxicology 32, no. 1 (July 1996): 31-44. Full Text
  - Gelzleichter, TR, Bermudez, E, Mangum, JB, Wong, BA, Everitt, JI, and Moss, OR. "Pulmonary and pleural responses in Fischer 344 rats following short-term inhalation of a synthetic vitreous fiber. I. Quantitation of lung and pleural fiber burdens." Fundamental and applied toxicology : official journal of the Society of Toxicology 30, no. 1 (March 1996): 31-38. Full Text
  - Gelzleichter, TR, Bermudez, E, Mangum, JB, Wong, BA, Moss, OR, and Everitt, JI. "Pulmonary and pleural responses in Fischer 344 rats following short-term inhalation of a synthetic vitreous fiber. II. Pathobiologic responses." Fundamental and applied toxicology : official journal of the Society of Toxicology 30, no. 1 (March 1996): 39-46. Full Text
  - Walker, C, Ahn, YT, Everitt, J, and Yuan, X. "Renal cell carcinoma development in the rat independent of alterations at the VHL gene locus." Molecular carcinogenesis 15, no. 2 (February 1996): 154-161. Full Text
  - GELZLEICHTER, TR, BERMUDEZ, E, MANGUM, JB, WONG, BA, EVERITT, JI, and MOSS, OR. "Pulmonary and Pleural Responses in Fischer 344 Rats Following Short-Term Inhalation of a Synthetic Vitreous Fiber." Toxicological Sciences 30, no. 1 (1996): 31-38. Full Text
  - GELZLEICHTER, TR, BERMUDEZ, E, MANGUM, JB, WONG, BA, MOSS, OR, and EVERITT, JI. "Pulmonary and Pleural Responses in Fischer 344 Rats Following Short-Term Inhalation of a Synthetic Vitreous Fiber." Toxicological Sciences 30, no. 1 (1996): 39-46. Full Text
  - Everitt, JI, Goldsworthy, TL, Wolf, DC, and Walker, CL. "Hereditary renal cell carcinoma in the Eker rat: a unique animal model for the study of cancer susceptibility." Toxicology letters 82-83 (December 1995): 621-625. Full Text
  - Howe, SR, Gottardis, MM, Everitt, JI, and Walker, C. "Estrogen stimulation and tamoxifen inhibition of leiomyoma cell growth in vitro and in vivo." Endocrinology 136, no. 11 (November 1995): 4996-5003. Full Text
  - Yeung, RS, Xiao, GH, Everitt, JI, Jin, F, and Walker, CL. "Allelic loss at the tuberous sclerosis 2 locus in spontaneous tumors in the Eker rat." Molecular carcinogenesis 14, no. 1 (September 1995): 28-36. Full Text
  - Rutten, AA, Bermudez, E, Stewart, W, Everitt, JI, and Walker, CL. "Expression of insulin-like growth factor II in spontaneously immortalized rat mesothelial and spontaneous mesothelioma cells: a potential autocrine role of insulin-like growth factor II." Cancer research 55, no. 16 (August 1995): 3634-3639.
  - Wolf, DC, Whiteley, HE, and Everitt, JI. "Preneoplastic and neoplastic lesions of rat hereditary renal cell tumors express markers of proximal and distal nephron." Veterinary pathology 32, no. 4 (July 1995): 379-386. Full Text
  - Everitt, JI, Wolf, DC, Howe, SR, Goldsworthy, TL, and Walker, C. "Rodent model of reproductive tract leiomyomata. Clinical and pathological features." The American journal of pathology 146, no. 6 (June 1995): 1556-1567.
  - Howe, SR, Everitt, JI, Gottardis, MM, and Walker, C. "Estrogen/antiestrogen responsiveness in an in vivo/in vitro model for myometrial tumorigenesis." Annals of the New York Academy of Sciences 761 (June 1995): 373-375. Full Text
  - Howe, SR, Gottardis, MM, Everitt, JI, Goldsworthy, TL, Wolf, DC, and Walker, C. "Rodent model of reproductive tract leiomyomata. Establishment and characterization of tumor-derived cell lines." The American journal of pathology 146, no. 6 (June 1995): 1568-1579.
  - Everitt, J, and Griffin, W. "Proposed IACUC guidelines for the review of rodent toxicology studies." Contemporary topics in laboratory animal science 34, no. 3 (May 1995): 72-74.
  - Horesovsky, G, Recio, L, Everitt, J, Goldsworthy, T, Wolf, DC, and Walker, C. "p53 status in spontaneous and dimethylnitrosamine-induced renal cell tumors from rats." Molecular carcinogenesis 12, no. 4 (April 1995): 236-240. Full Text
  - Walker, C, Everitt, J, Ferriola, PC, Stewart, W, Mangum, J, and Bermudez, E. "Autocrine growth stimulation by transforming growth factor alpha in asbestos-transformed rat mesothelial cells." Cancer research 55, no. 3 (February 1995): 530-536.
  - Everitt, JI. "Mechanisms of fiber-induced diseases: implications for the safety evaluation of synthetic vitreous fibers." Regulatory toxicology and pharmacology : RTP 20, no. 3 Pt 2 (December 1994): S68-S75. (Review)
  - Horesovsky, G, Ginsler, J, Everitt, J, and Walker, C. "Increased susceptibility to in vitro transformation of cells carrying the Eker tumor susceptibility mutation." Carcinogenesis 15, no. 10 (October 1994): 2183-2187. Full Text
  - Hard, GC, Long, PH, Crissman, JW, Everitt, JI, Yano, BL, and Bertram, TA. "Atypical tubule hyperplasia and renal tubule tumors in conventional rats on 90-day toxicity studies." Toxicologic pathology 22, no. 5 (September 1994): 489-496. Full Text
  - Rutten, AA, Bermudez, E, Mangum, JB, Wong, BA, Moss, OR, and Everitt, JI. "Mesothelial cell proliferation induced by intrapleural instillation of man-made fibers in rats and hamsters." Fundamental and applied toxicology : official journal of the Society of Toxicology 23, no. 1 (July 1994): 107-116. Full Text
  - Walker, C, Rutten, F, Yuan, X, Pass, H, Mew, DM, and Everitt, J. "Wilms' tumor suppressor gene expression in rat and human mesothelioma." Cancer research 54, no. 12 (June 1994): 3101-3106.
  - Everitt, JI, Bermudez, E, Mangum, JB, Wong, B, Moss, OR, Janszen, D, and Rutten, AA. "Pleural lesions in Syrian golden hamsters and Fischer-344 rats following intrapleural instillation of man-made ceramic or glass fibers." Toxicologic pathology 22, no. 3 (May 1994): 229-236. Full Text
  - Cattley, R. "Carcinogenicity and Toxicity of Inhaled Nitrobenzene in B6C3F1 Mice and F344 and CD Rats." Fundamental and Applied Toxicology 22, no. 3 (April 1994): 328-340. Full Text
  - Cattley, RC, Everitt, JI, Gross, EA, Moss, OR, Hamm, TE, and Popp, JA. "Carcinogenicity and toxicity of inhaled nitrobenzene in B6C3F1 mice and F344 and CD rats." Fundamental and applied toxicology : official journal of the Society of Toxicology 22, no. 3 (April 1994): 328-340. Full Text
  - Farris, G. "Carcinogenicity of Inhaled Benzene in CBA Mice." Fundamental and Applied Toxicology 20, no. 4 (May 1993): 503-507. Full Text
  - Farris, GM, Everitt, JI, Irons, RD, and Popp, JA. "Carcinogenicity of inhaled benzene in CBA mice." Fundamental and applied toxicology : official journal of the Society of Toxicology 20, no. 4 (May 1993): 503-507. Full Text
  - Satoh, H, Lamb, PW, Dong, JT, Everitt, J, Boreiko, C, Oshimura, M, and Barrett, JC. "Suppression of tumorigenicity of A549 lung adenocarcinoma cells by human chromosomes 3 and 11 introduced via microcell-mediated chromosome transfer." Molecular carcinogenesis 7, no. 3 (January 1993): 157-164. Full Text
  - Everitt, JI, Goldsworthy, TL, Wolf, DC, and Walker, CL. "Hereditary renal cell carcinoma in the Eker rat: a rodent familial cancer syndrome." The Journal of urology 148, no. 6 (December 1992): 1932-1936. Full Text
  - Kinnula, VL, Everitt, JI, Mangum, JB, Chang, LY, and Crapo, JD. "Antioxidant defense mechanisms in cultured pleural mesothelial cells." American Journal of Respiratory Cell and Molecular Biology 7, no. 1 (July 1992): 95-103. Full Text
  - Walker, C, Goldsworthy, TL, Wolf, DC, and Everitt, J. "Predisposition to renal cell carcinoma due to alteration of a cancer susceptibility gene." Science (New York, N.Y.) 255, no. 5052 (March 1992): 1693-1695. Full Text
  - Kinnula, VL, Chang, L, Everitt, JI, and Crapo, JD. "Oxidants and antioxidants in alveolar epithelial type II cells: in situ, freshly isolated, and cultured cells." The American journal of physiology 262, no. 1 Pt 1 (January 1992): L69-L77. Full Text
  - Lacy, SA, Mangum, JB, and Everitt, JI. "Cytochrome P-450- and glutathione-associated enzyme activities in freshly isolated enriched lung cell fractions from beta-naphthoflavone-treated male F344 rats." Toxicology 73, no. 2 (January 1992): 147-160. Full Text
  - Walker, C, Bermudez, E, Stewart, W, Bonner, J, Molloy, CJ, and Everitt, J. "Characterization of platelet-derived growth factor and platelet-derived growth factor receptor expression in asbestos-induced rat mesothelioma." Cancer research 52, no. 2 (January 1992): 301-306.
  - Walker, C, Everitt, J, and Barrett, JC. "Possible cellular and molecular mechanisms for asbestos carcinogenicity." American journal of industrial medicine 21, no. 2 (January 1992): 253-273. (Review) Full Text
  - Walker, C, Recio, L, Funaki, K, and Everitt, J. "Cytogenetic and molecular correlates between rodent and human renal cell carcinoma." Progress in clinical and biological research 376 (January 1992): 289-302. (Review)
  - CASANOVA, M. "Covalent binding of inhaled formaldehyde to DNA in the respiratory tract of rhesus monkeys: Pharmacolinetics, rat-to-monkey interspecies scaling, and extrapolation to man." Fundamental and Applied Toxicology 17, no. 2 (August 1991): 409-428. Full Text
  - Casanova, M, Morgan, KT, Steinhagen, WH, Everitt, JI, Popp, JA, and Heck, HD. "Covalent binding of inhaled formaldehyde to DNA in the respiratory tract of rhesus monkeys: pharmacokinetics, rat-to-monkey interspecies scaling, and extrapolation to man." Fundamental and applied toxicology : official journal of the Society of Toxicology 17, no. 2 (August 1991): 409-428. Full Text
  - Funaki, K, Everitt, J, Bermudez, E, and Walker, C. "Trisomy of rat chromosome 1 associated with mesothelial cell transformation." Cancer research 51, no. 15 (August 1991): 4059-4066.
  - Kinnula, VL, Everitt, JI, Whorton, AR, and Crapo, JD. "Hydrogen peroxide production by alveolar type II cells, alveolar macrophages, and endothelial cells." The American journal of physiology 261, no. 2 Pt 1 (August 1991): L84-L91. Full Text
  - Walker, C, Everitt, J, Freed, JJ, Knudson, AG, and Whiteley, LO. "Altered expression of transforming growth factor-alpha in hereditary rat renal cell carcinoma." Cancer research 51, no. 11 (June 1991): 2973-2978.
  - Kinnula, VL, Everitt, JI, Whorton, AR, and Crapo, JD. "Hydrogen peroxide production by alveolar type II cells, alveolar macrophages, and endothelial cells." American Journal of Physiology - Lung Cellular and Molecular Physiology 261, no. 2 5-1 (January 1, 1991).
  - Yoshitomi, K, Everitt, JI, and Boorman, GA. "Primary optic nerve meningiomas in F344 rats." Veterinary pathology 28, no. 1 (January 1991): 79-81. Full Text
  - Mangum, JB, Everitt, JI, Bonner, JC, Moore, LR, and Brody, AR. "Co-culture of primary pulmonary cells to model alveolar injury and translocation of proteins." In vitro cellular & developmental biology : journal of the Tissue Culture Association 26, no. 12 (December 1990): 1135-1143. Full Text
  - Bermudez, E, Everitt, J, and Walker, C. "Expression of growth factor and growth factor receptor RNA in rat pleural mesothelial cells in culture." Experimental cell research 190, no. 1 (September 1990): 91-98. Full Text
  - Everitt, JI, and Richter, CB. "Infectious diseases of the upper respiratory tract: implications for toxicology studies." Environmental health perspectives 85 (April 1990): 239-247. (Review) Full Text
  - Dubielzig, RR, Everitt, J, Shadduck, JA, and Albert, DM. "Clinical and morphologic features of post-traumatic ocular sarcomas in cats." Veterinary pathology 27, no. 1 (January 1990): 62-65. Full Text
  - Everitt, JI, Hesterberg, TW, and Boreiko, CJ. "The use of tracheal implants in toxicology and carcinogenesis research." Toxicology 60, no. 1-2 (January 1990): 27-40. (Review) Full Text
  - Monticello, TM, Morgan, KT, Everitt, JI, and Popp, JA. "Effects of formaldehyde gas on the respiratory tract of rhesus monkeys. Pathology and cell proliferation." The American journal of pathology 134, no. 3 (March 1989): 515-527.
  - Everitt, JI, Boreiko, CJ, Mangum, JB, Martin, JT, Iglehart, JD, and Hesterberg, TW. "Development of a tracheal implant xenograft model to expose human bronchial epithelial cells to toxic gases." Toxicologic pathology 17, no. 3 (January 1989): 465-473. Full Text
  - Everitt, JI, Ross, PW, and Davis, TW. "Urologic syndrome associated with wire caging in AKR mice." Laboratory animal science 38, no. 5 (October 1988): 609-611.
  - Casanova, M, Heck, HD, Everitt, JI, Harrington, WW, and Popp, JA. "Formaldehyde concentrations in the blood of rhesus monkeys after inhalation exposure." Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 26, no. 8 (August 1988): 715-716. Full Text
  - Everitt, JI, Ross, PW, Neptun, DA, and Mangum, JB. "Effect of a purified diet on dystrophic cardiac calcinosis in mice." Laboratory animal science 38, no. 4 (August 1988): 426-429.
  - Ross, PW, and Everitt, JI. "A nylon ball device for primate environmental enrichment." Laboratory animal science 38, no. 4 (August 1988): 481-483.
  - Everitt, JI, Olson, LM, Mangum, JB, and Visek, WJ. "High mortality with severe dystrophic cardiac calcinosis in C3H/OUJ mice fed high fat purified diets." Veterinary pathology 25, no. 2 (March 1988): 113-118. Full Text
  - Hesterberg, TW, Boreiko, CJ, Maness, SC, Iglehart, JD, Mangum, JB, and Everitt, JI. "Carcinogen-induced unscheduled DNA synthesis in xenotransplanted human tracheobronchial epithelium: comparison with rat tracheal epithelium." Carcinogenesis 9, no. 3 (March 1988): 467-472. Full Text
  - Whiteley, HE, Everitt, JI, Kakoma, I, James, MA, and Ristic, M. "Pathologic changes associated with fatal Plasmodium falciparum infection in the Bolivian squirrel monkey (Saimiri sciureus boliviensis)." The American journal of tropical medicine and hygiene 37, no. 1 (July 1987): 1-8.
  - Olson, LM, Clinton, SK, Everitt, JI, Johnston, PV, and Visek, WJ. "Lymphocyte activation, cell-mediated cytotoxicity and their relationship to dietary fat-enhanced mammary tumorigenesis in C3H/OUJ mice." The Journal of nutrition 117, no. 5 (May 1987): 955-963. Full Text
  - Everitt, JI, McLaughlin, SA, and Helper, LC. "Diagnostic exercise: eye lesions in rats." Laboratory animal science 37, no. 2 (April 1987): 203-204.
  - Hooser, SB, Beasley, VR, and Everitt, JI. "Effects of an insecticidal dip containing d-limonene in the cat." Journal of the American Veterinary Medical Association 189, no. 8 (October 1986): 905-908.
  - Sundberg, JP, and Everitt, JI. "Diagnostic exercise: lingual growths in rabbits." Laboratory animal science 36, no. 5 (October 1986): 499-500.
  - Everitt, JI, Shadduck, JA, Steinkamp, C, and Clabaugh, G. "Experimental Babesia bovis infection in Holstein calves." Veterinary pathology 23, no. 5 (September 1986): 556-562. Full Text
  - Zachary, JF, O'Brien, DP, Ingles, BW, Everitt, JI, and Parker, AJ. "Multicentric nerve sheath fibrosarcomas of multiple cranial nerve roots in two dogs." Journal of the American Veterinary Medical Association 188, no. 7 (April 1986): 723-726.
  - Gelberg, HB, Zachary, JF, Everitt, JI, Jensen, RC, and Smetzer, DL. "Sudden death in training and racing Thoroughbred horses." Journal of the American Veterinary Medical Association 187, no. 12 (December 1985): 1354-1356.
  - Shadduck, JA, Everitt, J, and Bay, P. "Use of in vitro cytotoxicity to rank ocular irritation of six surfactants." Alternative methods in toxicology. 3 (January 1985): 641-649.
  - Shamis, LD, Everitt, JI, and Baker, GJ. "Lymphosarcoma as the cause of ataxia in a horse." Journal of the American Veterinary Medical Association 184, no. 12 (June 1984): 1517-1518.
  - Everitt, JI, Fetter, AW, Kenney, RM, and Della-Ferra, MA. "Porcine necrotizing staphylococcal endometritis." Veterinary pathology 18, no. 1 (January 1981): 125-127. Full Text
  - Schafer, TW, Lieberman, M, Everitt, J, and Came, P. "Cutaneous herpes simplex virus infection of guinea pigs as a model for antiviral chemotherapy." Annals of the New York Academy of Sciences 284 (March 1977): 624-631. Full Text
Teaching & Mentoring
Recent Courses
- PATHOL 735S: Animal Models in Translational Research 2018
- PATHOL 786: Translational Aspects of Pathobiology 2018

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