Current Appointments & Affiliations
Professor Emeritus in Pathology
·
2023 - Present
Pathology,
Clinical Science Departments
Member of the Duke Cancer Institute
·
2017 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
SCORT-Cas13d Nanotherapy Precisely Targets the 'Undruggable' Transcription Factor HoxB13 in Metastatic Prostate Cancer In Vivo.
Journal Article Adv Sci (Weinh) · June 2025 Metastatic cancer, the primary cause of cancer mortality, frequently exhibits heightened dependence on certain transcription factors (TFs), which serve as master regulators of oncogenic signaling yet are often untargetable by small molecules. Selective Cel ... Full text Link to item CiteBioresorbable Suture Anchor Clips for Soft Tissue Wound Repair.
Journal Article Biomacromolecules · March 10, 2025 Mesh suture is an emerging technology for closing high-tension soft tissue wounds. However, bulky mesh surgical knots can irritate surrounding tissue and harbor bacteria, leading to an increased risk of infection and palpability. Thus, a degradable knotles ... Full text Link to item CiteLeptin augments IL-13-induced airway eotaxins and submucosal eosinophilia in obesity-associated asthma.
Journal Article J Allergy Clin Immunol · March 2025 BACKGROUND: Airway tissue eosinophilia can be an observed feature of obesity-associated type 2 (T2) asthma, but the processes mediating this inflammation are unknown. OBJECTIVE: To investigate a process whereby leptin, an adipokine elevated in obesity, pot ... Full text Open Access Link to item CiteRecent Grants
Identification and optimization of medical countermeasures for phosgene inhalation injuries
ResearchSignificant Contributor · Awarded by National Institutes of Health · 2024 - 2026Oxidative stress mechanisms regulating gamma-globin gene transcription in sickle cell disease
ResearchCollaborator · Awarded by National Institutes of Health · 2022 - 2026The Role of RBC Reactive Oxygen Species in Regulating Thrombotic Events During Aging
ResearchCollaborator · Awarded by National Institutes of Health · 2021 - 2026View All Grants
Education, Training & Certifications
Cornell University ·
1977
D.V.M.