Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Adjunct Professor of Pathology, College of Veterinary Medicine,, Department Of Pathology, North Carolina State University 2010 - 2015
  • D.V.M., Cornell University 1977
• 

  Duke Appointment History

  • Adjunct Professor in the Department of Pathology, Pathology, Clinical Science Departments 2015 - 2016
• Research
• 

  Selected Grants

  • Molecular Genetics of BBS awarded by National Institutes of Health 2002 - 2024
  • Role for TbetaRIII Shedding in the Tumor Microenvironment awarded by National Institutes of Health 2019 - 2024
  • Combatting Bladder Cancer by Inducing Epithelial Turnover awarded by National Institutes of Health 2019 - 2021
  • Advanced Technologies for Reducing Decompression Obligation and Risk 2018 - 2020
  • Empowering Duke's Precision Pathology Center with Quantitative Image Analysis to Support Discovery, Diagnostic Assay Development, and Immune Cell Monitoring 2018 - 2019
• Publications & Artistic Works
• 

  Selected Publications

  • Books

    • Andersen, A., C. Axten, D. M. Bernstein, P. Brochard, V. Castranova, K. Donaldson, P. Dumortier, et al. IARC monographs on the evaluation of carcinogenic risks to humans: Man-made vitreous fibres. Vol. 81, 2002.

  • Academic Articles

    • Han, Sang-Oh, Songtao Li, Angela McCall, Benjamin Arnson, Jeffrey I. Everitt, Haoyue Zhang, Sarah P. Young, Mai K. ElMallah, and Dwight D. Koeberl. “Comparisons of Infant and Adult Mice Reveal Age Effects for Liver Depot Gene Therapy in Pompe Disease.” Mol Ther Methods Clin Dev 17 (June 12, 2020): 133–42. https://doi.org/10.1016/j.omtm.2019.11.020.
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    • Cheng, Jeffrey, and Jeffrey Everitt. “Subglottic Cryotherapy: A Pilot Study in New Zealand White Rabbits.” Otolaryngol Head Neck Surg 162, no. 3 (March 2020): 326–28. https://doi.org/10.1177/0194599820902098.
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    • Kemeny, Hanna R., Aladine A. Elsamadicy, S Harrison Farber, Cosette D. Champion, Selena J. Lorrey, Pakawat Chongsathidkiet, Karolina I. Woroniecka, et al. “Targeting PD-L1 Initiates Effective Antitumor Immunity in a Murine Model of Cushing Disease.” Clin Cancer Res 26, no. 5 (March 1, 2020): 1141–51. https://doi.org/10.1158/1078-0432.CCR-18-3486.
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    • Ibrahim, M. M., J. L. Green, J. Everitt, D. Ruppert, R. Glisson, F. Leopardi, T. Risoli, M. Kuchibhatla, R. Reynolds, and H. Levinson. “Soft Tissue Anchoring Performance, Biomechanical Properties, and Tissue Reaction of a New Hernia Mesh Engineered to Address Hernia Occurrence and Recurrence.” Journal of Medical Devices, Transactions of the Asme 13, no. 4 (December 1, 2019). https://doi.org/10.1115/1.4043740.
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    • Han, Sang-Oh, Songtao Li, Jeffrey I. Everitt, and Dwight D. Koeberl. “Salmeterol with Liver Depot Gene Therapy Enhances the Skeletal Muscle Response in Murine Pompe Disease.” Hum Gene Ther 30, no. 7 (July 2019): 855–64. https://doi.org/10.1089/hum.2018.197.
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    • Chongsathidkiet, Pakawat, Christina Jackson, Shohei Koyama, Franziska Loebel, Xiuyu Cui, S Harrison Farber, Karolina Woroniecka, et al. “Author Correction: Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors.” Nat Med 25, no. 3 (March 2019): 529. https://doi.org/10.1038/s41591-019-0355-0.
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    • Wang, Lihua, Ergang Wang, Yi Wang, Robert Mines, Kun Xiang, Zhiguo Sun, Gaiting Zhou, et al. “miR-34a is a microRNA safeguard for Citrobacter-induced inflammatory colon oncogenesis.” Elife 7 (December 13, 2018). https://doi.org/10.7554/eLife.39479.
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    • Brayton, Cory F., Kelli L. Boyd, Jeffrey L. Everitt, David K. Meyerholz, Piper M. Treuting, and Brad Bolon. “An Introduction to Pathology in Biomedical Research: A Mission-Critical Specialty for Reproducibility and Rigor in Translational Research.” Ilar J 59, no. 1 (December 1, 2018): 1–3. https://doi.org/10.1093/ilar/ilz008.
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    • Everitt, Jeffrey I., Piper M. Treuting, Cheryl Scudamore, Rani Sellers, Patricia V. Turner, Jerrold M. Ward, and Caroline J. Zeiss. “Pathology Study Design, Conduct, and Reporting to Achieve Rigor and Reproducibility in Translational Research Using Animal Models.” Ilar J 59, no. 1 (December 1, 2018): 4–12. https://doi.org/10.1093/ilar/ily020.
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    • Chongsathidkiet, Pakawat, Christina Jackson, Shohei Koyama, Franziska Loebel, Xiuyu Cui, S Harrison Farber, Karolina Woroniecka, et al. “Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors.” Nat Med 24, no. 9 (September 2018): 1459–68. https://doi.org/10.1038/s41591-018-0135-2.
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    • Jung, Kwang-Woo, Kyung-Tae Lee, Anna F. Averette, Michael J. Hoy, Jeffrey Everitt, Joseph Heitman, and Yong-Sun Bahn. “Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex.” Sci Rep 8, no. 1 (May 25, 2018): 8132. https://doi.org/10.1038/s41598-018-26405-5.
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    • Hu, Fangyao, Hannah Martin, Amy Martinez, Jeffrey Everitt, Alaattin Erkanli, Walter T. Lee, Mark Dewhirst, and Nimmi Ramanujam. “Distinct Angiogenic Changes during Carcinogenesis Defined by Novel Label-Free Dark-Field Imaging in a Hamster Cheek Pouch Model.” Cancer Res 77, no. 24 (December 15, 2017): 7109–19. https://doi.org/10.1158/0008-5472.CAN-17-1058.
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    • Everitt, J. I., and B. R. Berridge. “The Role of the IACUC in the Design and Conduct of Animal Experiments that Contribute to Translational Success.” Ilar J 58, no. 1 (July 1, 2017): 129–34. https://doi.org/10.1093/ilar/ilx003.
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    • Kim, Yuna, Hyeong-Min Lee, Yan Xiong, Noah Sciaky, Samuel W. Hulbert, Xinyu Cao, Jeffrey I. Everitt, Jian Jin, Bryan L. Roth, and Yong-Hui Jiang. “Targeting the histone methyltransferase G9a activates imprinted genes and improves survival of a mouse model of Prader-Willi syndrome.” Nature Medicine 23, no. 2 (February 2017): 213–22. https://doi.org/10.1038/nm.4257.
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    • Bradley, Todd, Guang Yang, Olga Ilkayeva, T Matt Holl, Ruijun Zhang, Jinsong Zhang, Sampa Santra, et al. “HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism.” J Immunol 197, no. 12 (December 15, 2016): 4663–73. https://doi.org/10.4049/jimmunol.1601484.
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    • Brønstad, Aurora, Christian E. Newcomer, Thierry Decelle, Jeffrey I. Everitt, Javier Guillen, and Kathy Laber. “Current concepts of Harm-Benefit Analysis of Animal Experiments - Report from the AALAS-FELASA Working Group on Harm-Benefit Analysis - Part 1.” Lab Anim 50, no. 1 Suppl (June 2016): 1–20. https://doi.org/10.1177/0023677216642398.
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    • Laber, Kathy, Christian E. Newcomer, Thierry Decelle, Jeffrey I. Everitt, Javier Guillen, and Aurora Brønstad. “Recommendations for Addressing Harm-Benefit Analysis and Implementation in Ethical Evaluation - Report from the AALAS-FELASA Working Group on Harm-Benefit Analysis - Part 2.” Lab Anim 50, no. 1 Suppl (June 2016): 21–42. https://doi.org/10.1177/0023677216642397.
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    • Scudamore, Cheryl L., Elizabeth J. Soilleux, Natasha A. Karp, Ken Smith, Richard Poulsom, C Simon Herrington, Michael J. Day, et al. “Recommendations for minimum information for publication of experimental pathology data: MINPEPA guidelines.” J Pathol 238, no. 2 (January 2016): 359–67. https://doi.org/10.1002/path.4642.
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    • Shen, Zeli, Yan Feng, Alexander Sheh, Jeffrey Everitt, Frederick Bertram, Bruce J. Paster, and James G. Fox. “Isolation and characterization of a novel Helicobacter species, Helicobacter jaachi sp. nov., from common marmosets (Callithrix jaachus).” J Med Microbiol 64, no. 9 (September 2015): 1063–73. https://doi.org/10.1099/jmm.0.000113.
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    • Everitt, Jeffrey I. “The future of preclinical animal models in pharmaceutical discovery and development: a need to bring in cerebro to the in vivo discussions.” Toxicol Pathol 43, no. 1 (January 2015): 70–77. https://doi.org/10.1177/0192623314555162.
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    • Rose, M., J. Everitt, H. Hedrich, J. Schofield, M. Dennis, E. Scott, G. Griffin, and G. ICLAS Working Group on Harmonization. “ICLAS Working Group on Harmonization: international guidance concerning the production care and use of genetically-altered animals.” Lab Anim 47, no. 3 (July 2013): 146–52. https://doi.org/10.1177/0023677213479338.
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    • Rose, M., J. Everitt, H. Hedrich, J. Schofield, M. Dennis, E. Scott, G. Griffin, and G. ICLAS Working Group on Harmonization. “ICLAS Working Group on Harmonization: international guidance concerning the production care and use of genetically-altered animals.” Laboratory Animals 47, no. 3 (July 1, 2013): 142–52.
    • Boyle, M. C., M. H. Boyle, and M. H. Sixth Rodent Pathology Course Committee. “Meeting report: Urinary Pathology; sixth Research Triangle Park Rodent Pathology Course.” Veterinary Pathology 50, no. 3 (May 2013): 563–68. https://doi.org/10.1177/0300985813480217.
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    • Greathouse, K Leigh, Tiffany Bredfeldt, Jeffrey I. Everitt, Kevin Lin, Tia Berry, Kurunthachalam Kannan, Megan L. Mittelstadt, Shuk-mei Ho, and Cheryl L. Walker. “Environmental estrogens differentially engage the histone methyltransferase EZH2 to increase risk of uterine tumorigenesis.” Mol Cancer Res 10, no. 4 (April 2012): 546–57. https://doi.org/10.1158/1541-7786.MCR-11-0605.
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    • Broaddus, V Courtney, Jeffrey I. Everitt, Brad Black, and Agnes B. Kane. “Non-neoplastic and neoplastic pleural endpoints following fiber exposure.” J Toxicol Environ Health B Crit Rev 14, no. 1–4 (2011): 153–78. https://doi.org/10.1080/10937404.2011.556049.
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    • Workman, P., E. O. Aboagye, F. Balkwill, A. Balmain, G. Bruder, D. J. Chaplin, J. A. Double, et al. “Guidelines for the welfare and use of animals in cancer research.” Br J Cancer 102, no. 11 (May 25, 2010): 1555–77. https://doi.org/10.1038/sj.bjc.6605642.
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    • Kirby, Patrick J., Cassandra J. Shines, Genie J. Taylor, Ronald W. Bousquet, Herman C. Price, Jeffrey I. Everitt, and Daniel L. Morgan. “Pleural effects of indium phosphide in B6C3F1 mice: nonfibrous particulate induced pleural fibrosis.” Exp Lung Res 35, no. 10 (December 2009): 858–82. https://doi.org/10.3109/01902140902980961.
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    • Ryman-Rasmussen, Jessica P., Mark F. Cesta, Arnold R. Brody, Jeanette K. Shipley-Phillips, Jeffrey I. Everitt, Earl W. Tewksbury, Owen R. Moss, et al. “Inhaled carbon nanotubes reach the subpleural tissue in mice.” Nat Nanotechnol 4, no. 11 (November 2009): 747–51. https://doi.org/10.1038/nnano.2009.305.
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    • Lanzoni, Anna, Alessandro Piaia, Jeffrey Everitt, Ivo Faustinelli, Rossella Defazio, Luca Cavaliere, and Patrizia Cristofori. “Early onset of spontaneous renal preneoplastic and neoplastic lesions in young conventional rats in toxicity studies.” Toxicol Pathol 35, no. 4 (June 2007): 589–93. https://doi.org/10.1080/01926230701383202.
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    • Laping, Nicholas J., Jeffrey I. Everitt, Kendall S. Frazier, Mark Burgert, Melisa J. Portis, Caprice Cadacio, Leslie I. Gold, and Cheryl L. Walker. “Tumor-specific efficacy of transforming growth factor-beta RI inhibition in Eker rats.” Clin Cancer Res 13, no. 10 (May 15, 2007): 3087–99. https://doi.org/10.1158/1078-0432.CCR-06-1811.
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    • Mally, Angela, Cheryl L. Walker, Jeffrey I. Everitt, Wolfgang Dekant, and Spiros Vamvakas. “Analysis of renal cell transformation following exposure to trichloroethene in vivo and its metabolite S-(dichlorovinyl)-L-cysteine in vitro.” Toxicology 224, no. 1–2 (July 5, 2006): 108–18. https://doi.org/10.1016/j.tox.2006.04.036.
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    • Roberts, Elizabeth S., Anna M. Bonner, Jeffrey I. Everitt, and David C. Dorman. “What's your diagnosis? Lethargy and hind limb paralysis in a day-23 timed pregnant rat.” Lab Anim (Ny) 35, no. 2 (February 2006): 19–20. https://doi.org/10.1038/laban0206-19.
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    • Everitt, Jeffrey I., and Steven J. Shapiro. “The art and science of introducing animals to the research environment.” Ilar Journal 47, no. 4 (January 2006): 281–82. https://doi.org/10.1093/ilar.47.4.281.
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    • Schapiro, Steven A., and Jeffrey I. Everitt. “Preparation of animals for use in the laboratory: issues and challenges for the Institutional Animal Care and Use Committee (IACUC).” Ilar Journal 47, no. 4 (January 2006): 370–75. https://doi.org/10.1093/ilar.47.4.370.
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    • Floyd, Heather S., Charles L. Farnsworth, Nancy D. Kock, Melissa C. Mizesko, Joy L. Little, Stephanie T. Dance, Jeff Everitt, Jay Tichelaar, Jeffrey A. Whitsett, and Mark Steven Miller. “Conditional expression of the mutant Ki-rasG12C allele results in formation of benign lung adenomas: development of a novel mouse lung tumor model.” Carcinogenesis 26, no. 12 (December 2005): 2196–2206. https://doi.org/10.1093/carcin/bgi190.
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    • Corton, J Christopher, Udayan Apte, Steven P. Anderson, Pallavi Limaye, Lawrence Yoon, John Latendresse, Corrie Dunn, et al. “Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors.” J Biol Chem 279, no. 44 (October 29, 2004): 46204–12. https://doi.org/10.1074/jbc.M406739200.
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    • Mangum, James, Edilberto Bermudez, Madhabananda Sar, and Jeffrey Everitt. “Osteopontin expression in particle-induced lung disease.” Exp Lung Res 30, no. 7 (October 2004): 585–98. https://doi.org/10.1080/01902140490476346.
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    • Dong, Jing, Jeffrey I. Everitt, Serrine S. Lau, and Terrence J. Monks. “Induction of ERK1/2 and histone H3 phosphorylation within the outer stripe of the outer medulla of the Eker rat by 2,3,5-tris-(glutathion-S-yl)hydroquinone.” Toxicol Sci 80, no. 2 (August 2004): 350–57. https://doi.org/10.1093/toxsci/kfh160.
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    • Dorman, David C., Brian E. McManus, Carl U. Parkinson, Chris A. Manuel, Anna M. McElveen, and Jeffrey I. Everitt. “Nasal toxicity of manganese sulfate and manganese phosphate in young male rats following subchronic (13-week) inhalation exposure.” Inhal Toxicol 16, no. 6–7 (June 2004): 481–88. https://doi.org/10.1080/08958370490439687.
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    • Gardner, Sarah Y., John K. McGee, Urmila P. Kodavanti, Allen Ledbetter, Jeffrey I. Everitt, Darrell W. Winsett, Donald L. Doerfler, and Daniel L. Costa. “Emission-particle-induced ventilatory abnormalities in a rat model of pulmonary hypertension.” Environ Health Perspect 112, no. 8 (June 2004): 872–78. https://doi.org/10.1289/ehp.6583.
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    • Kleymenova, Elena, Jeffrey I. Everitt, Linda Pluta, Melisa Portis, James R. Gnarra, and Cheryl Lyn Walker. “Susceptibility to vascular neoplasms but no increased susceptibility to renal carcinogenesis in Vhl knockout mice.” Carcinogenesis 25, no. 3 (March 2004): 309–15. https://doi.org/10.1093/carcin/bgh017.
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    • Bermudez, Edilberto, James B. Mangum, Brian A. Wong, Bahman Asgharian, Paul M. Hext, David B. Warheit, and Jeffrey I. Everitt. “Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles.” Toxicol Sci 77, no. 2 (February 2004): 347–57. https://doi.org/10.1093/toxsci/kfh019.
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    • Everitt, Jeffrey I., and Paul M. D. Foster. “Laboratory animal science issues in the design and conduct of studies with endocrine-active compounds.” Ilar J 45, no. 4 (2004): 417–24. https://doi.org/10.1093/ilar.45.4.417.
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    • Gardner, S. Y., J. K. McGee, U. P. Kodavanti, A. Ledbetter, J. I. Everitt, D. W. Winsett, D. L. Doerfler, and D. L. Costa. “Emmission-particle-induced ventilatory abnormalities in a rat model of pulmonary hypertension.” Environmental Health Perspectives 112, no. 8 (January 1, 2004): 872–78. https://doi.org/10.1289/ehp.6583.
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    • Walker, Cheryl Lyn, Deborah Hunter, and Jeffery I. Everitt. “Uterine leiomyoma in the Eker rat: a unique model for important diseases of women.” Genes Chromosomes Cancer 38, no. 4 (December 2003): 349–56. https://doi.org/10.1002/gcc.10281.
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    • Faiola, Brenda, Alison K. Bauer, Elizabeth S. Fuller, Victoria A. Wong, Linda J. Pluta, Diane J. Abernethy, James B. Mangum, Jeffrey I. Everitt, and Leslie Recio. “Variations in Prkdc and susceptibility to benzene-induced toxicity in mice.” Toxicol Sci 75, no. 2 (October 2003): 321–32. https://doi.org/10.1093/toxsci/kfg186.
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    • Bermudez, Edilberto, James B. Mangum, Owen R. Moss, Brian A. Wong, and Jeffrey I. Everitt. “Pleural dosimetry and pathobiological responses in rats and hamsters exposed subchronically to MMVF 10a fiberglass.” Toxicological Sciences : An Official Journal of the Society of Toxicology 74, no. 1 (July 2003): 165–73. https://doi.org/10.1093/toxsci/kfg092.
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    • Hill, G. D., J. B. Mangum, O. R. Moss, and J. I. Everitt. “Soluble ICAM-1, MCP-1, and MIP-2 protein secretion by rat pleural mesothelial cells following exposure to amosite asbestos.” Experimental Lung Research 29, no. 5 (July 1, 2003): 277–90. https://doi.org/10.1080/01902140303788.
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    • Hill, Georgette D., James B. Mangum, Owen R. Moss, and Jeffrey I. Everitt. “Soluble ICAM-1, MCP-1, and MIP-2 protein secretion by rat pleural mesothelial cells following exposure to amosite asbestos.” Exp Lung Res 29, no. 5 (July 2003): 277–90. https://doi.org/10.1080/01902140303788.
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    • Bauer, Alison K., Brenda Faiola, Diane J. Abernethy, Rosemarie Marchan, Linda J. Pluta, Victoria A. Wong, Frank J. Gonzalez, et al. “Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity.” Toxicol Sci 72, no. 2 (April 2003): 201–9. https://doi.org/10.1093/toxsci/kfg024.
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    • Lambert, Amy L., Frances S. Trasti, James B. Mangum, and Jeffrey I. Everitt. “Effect of preexposure to ultrafine carbon black on respiratory syncytial virus infection in mice.” Toxicol Sci 72, no. 2 (April 2003): 331–38. https://doi.org/10.1093/toxsci/kfg031.
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    • Lambert, Amy L., James B. Mangum, Michael P. DeLorme, and Jeffrey I. Everitt. “Ultrafine carbon black particles enhance respiratory syncytial virus-induced airway reactivity, pulmonary inflammation, and chemokine expression.” Toxicological Sciences : An Official Journal of the Society of Toxicology 72, no. 2 (April 2003): 339–46. https://doi.org/10.1093/toxsci/kfg032.
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    • Bauer, Alison K., Brenda Faiola, Diane J. Abernethy, Rosemarie Marchan, Linda J. Pluta, Vicki A. Wong, Kay Roberts, et al. “Genetic susceptibility to benzene-induced toxicity: role of NADPH: quinone oxidoreductase-1.” Cancer Res 63, no. 5 (March 1, 2003): 929–35.
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    • Cai, Shengli, Jeffrey I. Everitt, Hiroyuki Kugo, Jennifer Cook, Elena Kleymenova, and Cheryl Lyn Walker. “Polycystic kidney disease as a result of loss of the tuberous sclerosis 2 tumor suppressor gene during development.” Am J Pathol 162, no. 2 (February 2003): 457–68. https://doi.org/10.1016/S0002-9440(10)63840-0.
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    • Bermudez, Edilberto, James B. Mangum, Bahman Asgharian, Brian A. Wong, Edward E. Reverdy, Derek B. Janszen, Paul M. Hext, David B. Warheit, and Jeffrey I. Everitt. “Long-term pulmonary responses of three laboratory rodent species to subchronic inhalation of pigmentary titanium dioxide particles.” Toxicol Sci 70, no. 1 (November 2002): 86–97. https://doi.org/10.1093/toxsci/70.1.86.
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    • Seely, John C., Joseph K. Haseman, Abraham Nyska, Douglas C. Wolf, Jeffrey I. Everitt, and James R. Hailey. “The effect of chronic progressive nephropathy on the incidence of renal tubule cell neoplasms in control male F344 rats.” Toxicol Pathol 30, no. 6 (November 2002): 681–86. https://doi.org/10.1080/01926230290166779.
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    • Yoon, Hae-Seong, Terrence J. Monks, Jeffrey I. Everitt, Cheryl L. Walker, and Serrine S. Lau. “Cell proliferation is insufficient, but loss of tuberin is necessary, for chemically induced nephrocarcinogenicity.” Am J Physiol Renal Physiol 283, no. 2 (August 2002): F262–70. https://doi.org/10.1152/ajprenal.00261.2001.
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    • Yoon, H. S., T. J. Monks, J. I. Everitt, C. L. Walker, and S. S. Lau. “Cell proliferation is insufficient, but loss of tuberin is necessary, for chemically induced nephrocarcinogenicity.” American Journal of Physiology  Renal Physiology 283, no. 2 52-2 (July 27, 2002).
    • Constan, Alexander A., Brian A. Wong, Jeffrey I. Everitt, and Byron E. Butterworth. “Chloroform inhalation exposure conditions necessary to initiate liver toxicity in female B6C3F1 mice.” Toxicological Sciences : An Official Journal of the Society of Toxicology 66, no. 2 (April 2002): 201–8. https://doi.org/10.1093/toxsci/66.2.201.
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    • Hesterberg, T. W., G. A. Hart, W. C. Miiller, G. Chase, R. A. Rogers, J. B. Mangum, and J. I. Everitt. “Use of short-term assays to evaluate the potential toxicity of two new biosoluble glasswool fibers.” Inhal Toxicol 14, no. 3 (March 2002): 217–46. https://doi.org/10.1080/08958370252809022.
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    • You, Li, Mercedes Casanova, Erika J. Bartolucci, Mary W. Fryczynski, David C. Dorman, Jeffrey I. Everitt, Kevin W. Gaido, Susan M. Ross, and Henry d’A Heck Hd. “Combined effects of dietary phytoestrogen and synthetic endocrine-active compound on reproductive development in Sprague-Dawley rats: genistein and methoxychlor.” Toxicological Sciences : An Official Journal of the Society of Toxicology 66, no. 1 (March 2002): 91–104. https://doi.org/10.1093/toxsci/66.1.91.
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    • Torti, V. R., A. J. Cobb, J. I. Everitt, M. W. Marshall, G. A. Boorman, and B. E. Butterworth. “Nephrotoxicity and hepatotoxicity induced by inhaled bromodichloromethane in wild-type and p53-heterozygous mice.” Toxicological Sciences : An Official Journal of the Society of Toxicology 64, no. 2 (December 2001): 269–80. https://doi.org/10.1093/toxsci/64.2.269.
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    • Recio, L., and J. Everitt. “Use of genetically modified mouse models for evaluation of carcinogenic risk: considerations for the laboratory animal scientist.” Comp Med 51, no. 5 (October 2001): 399–405.
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    • Dye, J. A., J. R. Lehmann, J. K. McGee, D. W. Winsett, A. D. Ledbetter, J. I. Everitt, A. J. Ghio, and D. L. Costa. “Acute pulmonary toxicity of particulate matter filter extracts in rats: Coherence with epidemiologic studies in Utah valley residents.” Environmental Health Perspectives 109, no. SUPPL. 3 (July 12, 2001): 395–403.
    • Dye, J. A., J. R. Lehmann, J. K. McGee, D. W. Winsett, A. D. Ledbetter, J. I. Everitt, A. J. Ghio, and D. L. Costa. “Acute pulmonary toxicity of particulate matter filter extracts in rats: coherence with epidemiologic studies in Utah Valley residents.” Environ Health Perspect 109 Suppl 3 (June 2001): 395–403. https://doi.org/10.1289/ehp.01109s3395.
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    • Borghoff, S. J., J. S. Prescott, D. B. Janszen, B. A. Wong, and J. I. Everitt. “alpha 2u-Globulin nephropathy, renal cell proliferation, and dosimetry of inhaled tert-butyl alcohol in male and female F-344 rats.” Toxicological Sciences : An Official Journal of the Society of Toxicology 61, no. 1 (May 2001): 176–86. https://doi.org/10.1093/toxsci/61.1.176.
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    • Kleymenova, E., O. Ibraghimov-Beskrovnaya, H. Kugoh, J. Everitt, H. Xu, K. Kiguchi, G. Landes, P. Harris, and C. Walker. “Tuberin-dependent membrane localization of polycystin-1: a functional link between polycystic kidney disease and the TSC2 tumor suppressor gene.” Molecular Cell 7, no. 4 (April 2001): 823–32. https://doi.org/10.1016/s1097-2765(01)00226-x.
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    • Borghoff, S. J., J. S. Prescott, D. B. Janszen, B. A. Wong, and J. I. Everitt. “α2u-Globulin nephropathy, renal cell proliferation, and dosimetry of inhaled tert-butyl alcohol in male and female F-344 rats.” Toxicological Sciences 61, no. 1 (January 1, 2001): 176–86.
    • Lau, S. S., H. S. Yoon, S. K. Patel, J. I. Everitt, C. L. Walker, and T. J. Monks. “Mutagenicity and carcinogenicity of biological reactive intermediate's derived from a "non-genotoxic" carcinogen.” Adv Exp Med Biol 500 (2001): 83–92.
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    • Lau, S. S., T. J. Monks, J. I. Everitt, E. Kleymenova, and C. L. Walker. “Carcinogenicity of a nephrotoxic metabolite of the "nongenotoxic" carcinogen hydroquinone.” Chem Res Toxicol 14, no. 1 (January 2001): 25–33. https://doi.org/10.1021/tx000161g.
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    • Newbold, R. R., R. P. DiAugustine, J. I. Risinger, J. I. Everitt, D. K. Walmer, E. C. Parrott, and D. Dixon. “Advances in uterine leiomyoma research: conference overview, summary, and future research recommendations.” Environ Health Perspect 108 Suppl 5 (October 2000): 769–73. https://doi.org/10.1289/ehp.00108s5769.
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    • Wolf, D. C., T. L. Goldsworthy, D. B. Janszen, R. Harden, E. M. Donner, C. S. David, and J. I. Everitt. “Promotion by sodium barbital induces early development but does not increase the multiplicity of hereditary renal tumors in Eker rats.” Carcinogenesis 21, no. 8 (August 2000): 1553–58.
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    • Walker, C. L., K. D. Burroughs, B. Davis, K. Sowell, J. I. Everitt, and R. Fuchs-Young. “Preclinical evidence for therapeutic efficacy of selective estrogen receptor modulators for uterine leiomyoma.” J Soc Gynecol Investig 7, no. 4 (July 2000): 249–56.
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    • Everitt, J. I., J. B. Mangum, E. Bermudez, B. A. Wong, B. Asgharian, E. E. Reverdy, P. M. Hext, and D. B. Warheit. “Comparison of Selected Pulmonary Responses of Rats, Mice, and Syrian Golden Hamsters to Inhaled Pigmentary Titanium Dioxide.” Inhalation Toxicology 12 Suppl 3 (January 2000): 275–82. https://doi.org/10.1080/08958378.2000.11463223.
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    • Newbold, R. R., R. P. DiAugustine, J. I. Risinger, J. I. Everitt, D. K. Walmer, E. C. Parrott, and D. Dixon. “Advances in uterine leiomyoma research: Conference overview, summary, and future research recommendations.” Environmental Health Perspectives 108, no. SUPPL. 5 (2000): 769–73.
    • Reverdy, E. E., E. Bermudez, J. B. Mangum, B. Asgharian, B. Wong, and J. I. Everitt. “Protein Carbonyls in Bronchoalveolar Lavage Fluid in Mice, Rats and Hamsters Following Inhalation of Pigmentary Titanium Dioxide Particles.” Inhalation Toxicology 12 Suppl 3 (January 2000): 283–89. https://doi.org/10.1080/08958378.2000.11463224.
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    • Kleymenova, E. V., G. Horesovsky, L. N. Pylev, and J. Everitt. “Mesotheliomas induced in rats by the fibrous mineral erionite are independent from p53 alterations.” Cancer Lett 147, no. 1–2 (December 1, 1999): 55–61. https://doi.org/10.1016/s0304-3835(99)00275-x.
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    • Constan, A. A., C. S. Sprankle, J. M. Peters, G. L. Kedderis, J. I. Everitt, B. A. Wong, F. L. Gonzalez, and B. E. Butterworth. “Metabolism of chloroform by cytochrome P450 2E1 is required for induction of toxicity in the liver, kidney, and nose of male mice.” Toxicol Appl Pharmacol 160, no. 2 (October 15, 1999): 120–26. https://doi.org/10.1006/taap.1999.8756.
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    • Hesterberg, T. W., C. Axten, E. E. McConnell, G. A. Hart, W. Miiller, J. Chevalier, J. Everitt, P. Thevenaz, and G. Oberdörster. “Studies on the inhalation toxicology of two fiberglasses and amosite asbestos in the syrian golden hamster. Part I. Results of a subchronic study and dose selection for a chronic study.” Inhal Toxicol 11, no. 9 (September 1999): 747–84. https://doi.org/10.1080/089583799196745.
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    • McConnell, E. E., C. Axten, T. W. Hesterberg, J. Chevalier, W. C. Miiller, J. Everitt, G. Oberdörster, G. R. Chase, P. Thevenaz, and P. Kotin. “Studies on the inhalation toxicology of two fiberglasses and amosite asbestos in the Syrian golden hamster. Part II. Results of chronic exposure.” Inhalation Toxicology 11, no. 9 (September 1999): 785–835. https://doi.org/10.1080/089583799196754.
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    • Gelzleichter, T. R., E. Bermudez, J. B. Mangum, B. A. Wong, D. B. Janszen, O. R. Moss, and J. I. Everitt. “Comparison of pulmonary and pleural responses of rats and hamsters to inhaled refractory ceramic fibers.” Toxicological Sciences : An Official Journal of the Society of Toxicology 49, no. 1 (May 1999): 93–101. https://doi.org/10.1093/toxsci/49.1.93.
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    • Everitt, J. “Experimental approaches for studies of particulate matter: the case for stronger consideration of dosimetric and exposure issues.” Experimental Lung Research 24, no. 6 (November 1998): 705–7. https://doi.org/10.3109/01902149809099590.
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    • Wolf, D. C., T. L. Goldsworthy, E. M. Donner, R. Harden, B. Fitzpatrick, and J. I. Everitt. “Estrogen treatment enhances hereditary renal tumor development in Eker rats.” Carcinogenesis 19, no. 11 (November 1998): 2043–47. https://doi.org/10.1093/carcin/19.11.2043.
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    • Fowler, L., J. Everitt, J. L. Stevens, and S. Jaken. “Redistribution and enhanced protein kinase C-mediated phosphorylation of alpha- and gamma-adducin during renal tumor progression.” Cell Growth Differ 9, no. 5 (May 1998): 405–13.
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    • Butterworth, B. E., M. V. Templin, A. A. Constan, C. S. Sprankle, B. A. Wong, L. J. Pluta, J. I. Everitt, and L. Recio. “Long-term mutagenicity studies with chloroform and dimethylnitrosamine in female lacI transgenic B6C3F1 mice.” Environ Mol Mutagen 31, no. 3 (1998): 248–56. https://doi.org/10.1002/(sici)1098-2280(1998)31:3<248::aid-em6>3.0.co;2-g.
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    • Everitt, J. I., T. R. Gelzleichter, E. Bermudez, J. B. Mangum, B. A. Wong, D. B. Janszen, and O. R. Moss. “Comparison of pleural responses of rats and hamsters to subchronic inhalation of refractory ceramic fibers.” Environ Health Perspect 105 Suppl 5 (September 1997): 1209–13. https://doi.org/10.1289/ehp.97105s51209.
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    • Everitt, J. I., T. R. Gelzleichter, E. Bermudez, J. B. Mangum, B. A. Wong, D. B. Janszen, and O. R. Moss. “Comparison of pleural responses of rats and hamsters to subchronic inhalation of refractory ceramic fibers.” Environmental Health Perspectives 105, no. suppl 5 (September 1997): 1209–13. https://doi.org/10.1289/ehp.97105s51209.
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    • Hesterberg, T. W., C. Axten, E. E. McConnell, G. Oberdörster, J. Everitt, W. C. Miiller, J. Chevalier, G. R. Chase, and P. Thevenaz. “Chronic inhalation study of fiber glass and amosite asbestos in hamsters: twelve-month preliminary results.” Environmental Health Perspectives 105 Suppl 5 (September 1997): 1223–29. https://doi.org/10.2307/3433537.
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    • King-Herbert, A. P., T. W. Hesterburg, P. P. Thevenaz, T. E. Hamm, O. R. Moss, D. B. Janszen, and J. I. Everitt. “Effects of immobilization restraint on Syrian golden hamsters.” Lab Anim Sci 47, no. 4 (August 1997): 362–66.
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    • Everitt, J. I., C. L. Walker, T. W. Goldsworthy, and D. C. Wolf. “Altered expression of transforming growth factor-alpha: an early event in renal cell carcinoma development.” Mol Carcinog 19, no. 3 (July 1997): 213–19.
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    • Medinsky, M. A., D. C. Dorman, J. A. Bond, O. R. Moss, D. B. Janszen, and J. I. Everitt. “Pharmacokinetics of methanol and formate in female cynomolgus monkeys exposed to methanol vapors.” Res Rep Health Eff Inst, no. 77 (June 1997): 1–30.
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    • Gardner, S. Y., A. R. Brody, J. B. Mangum, and J. I. Everitt. “Chrysotile asbestos and H2O2 increase permeability of alveolar epithelium.” Exp Lung Res 23, no. 1 (January 1997): 1–16. https://doi.org/10.3109/01902149709046044.
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    • Howe, S. R., J. L. Everitt, M. M. Gottardis, and C. Walker. “Rodent model of reproductive tract leiomyomata: characterization and use in preclinical therapeutic studies.” Prog Clin Biol Res 396 (1997): 205–15.
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    • Gelzleichter, T. R., J. B. Mangum, E. Bermudez, B. A. Wong, O. R. Moss, and J. I. Everitt. “Pulmonary and pleural leukocytes from F344 rats produce elevated levels of fibronectin following inhalation of refractory ceramic fibers.” Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Fur Toxikologische Pathologie 48, no. 6 (November 1996): 487–89. https://doi.org/10.1016/s0940-2993(96)80062-5.
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    • Hesterberg, T. W., E. E. McConnel, W. C. Miiller, J. Chevalier, J. Everitt, P. Thevenaz, H. Fleissner, and G. Oberdörster. “Use of lung toxicity and lung particle clearance to estimate the maximum tolerated dose (MTD) for a fiber glass chronic inhalation study in the rat.” Fundam Appl Toxicol 32, no. 1 (July 1996): 31–44. https://doi.org/10.1006/faat.1996.0104.
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    • Gelzleichter, T. R., E. Bermudez, J. B. Mangum, B. A. Wong, J. I. Everitt, and O. R. Moss. “Pulmonary and pleural responses in Fischer 344 rats following short-term inhalation of a synthetic vitreous fiber. I. Quantitation of lung and pleural fiber burdens.” Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology 30, no. 1 (March 1996): 31–38. https://doi.org/10.1006/faat.1996.0040.
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    • Gelzleichter, T. R., E. Bermudez, J. B. Mangum, B. A. Wong, O. R. Moss, and J. I. Everitt. “Pulmonary and pleural responses in Fischer 344 rats following short-term inhalation of a synthetic vitreous fiber. II. Pathobiologic responses.” Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology 30, no. 1 (March 1996): 39–46. https://doi.org/10.1006/faat.1996.0041.
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    • Walker, C., Y. T. Ahn, J. Everitt, and X. Yuan. “Renal cell carcinoma development in the rat independent of alterations at the VHL gene locus.” Mol Carcinog 15, no. 2 (February 1996): 154–61. https://doi.org/10.1002/(SICI)1098-2744(199602)15:2<154::AID-MC8>3.0.CO;2-J.
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    • GELZLEICHTER, THOMAS R., E. D. I. L. B. E. R. T. O. BERMUDEZ, JAMES B. MANGUM, BRAIN A. WONG, JEFFREY I. EVERITT, and OWEN R. MOSS. “Pulmonary and Pleural Responses in Fischer 344 Rats Following Short-Term Inhalation of a Synthetic Vitreous Fiber.” Toxicological Sciences 30, no. 1 (1996): 31–38. https://doi.org/10.1093/toxsci/30.1.31.
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    • GELZLEICHTER, THOMAS R., E. D. I. L. B. E. R. T. O. BERMUDEZ, JAMES B. MANGUM, BRAIN A. WONG, OWEN R. MOSS, and JEFFREY I. EVERITT. “Pulmonary and Pleural Responses in Fischer 344 Rats Following Short-Term Inhalation of a Synthetic Vitreous Fiber.” Toxicological Sciences 30, no. 1 (1996): 39–46. https://doi.org/10.1093/toxsci/30.1.39.
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    • Walker, C., Y. T. Ahn, J. Everitt, and X. Yuan. “Renal cell carcinoma development in the rat independent of alterations at the VHL gene locus.” Molecular Carcinogenesis 15, no. 2 (January 1, 1996): 154–61. https://doi.org/10.1002/(SICI)1098-2744(199602)15:2<154::AID-MC8>3.0.CO;2-J.
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    • Everitt, J. I., T. L. Goldsworthy, D. C. Wolf, and C. L. Walker. “Hereditary renal cell carcinoma in the Eker rat: a unique animal model for the study of cancer susceptibility.” Toxicol Lett 82–83 (December 1995): 621–25. https://doi.org/10.1016/0378-4274(95)03506-0.
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    • Howe, S. R. “Estrogen stimulation and tamoxifen inhibition of leiomyoma cell growth in vitro and in vivo.” Endocrinology 136, no. 11 (November 1, 1995): 4996–5003. https://doi.org/10.1210/en.136.11.4996.
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    • Howe, S. R., M. M. Gottardis, J. I. Everitt, and C. Walker. “Estrogen stimulation and tamoxifen inhibition of leiomyoma cell growth in vitro and in vivo.” Endocrinology 136, no. 11 (November 1995): 4996–5003. https://doi.org/10.1210/endo.136.11.7588234.
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    • Yeung, R. S., G. H. Xiao, J. I. Everitt, F. Jin, and C. L. Walker. “Allelic loss at the tuberous sclerosis 2 locus in spontaneous tumors in the Eker rat.” Mol Carcinog 14, no. 1 (September 1995): 28–36. https://doi.org/10.1002/mc.2940140107.
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    • Rutten, A. A., E. Bermudez, W. Stewart, J. I. Everitt, and C. L. Walker. “Expression of insulin-like growth factor II in spontaneously immortalized rat mesothelial and spontaneous mesothelioma cells: a potential autocrine role of insulin-like growth factor II.” Cancer Res 55, no. 16 (August 15, 1995): 3634–39.
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    • Wolf, D. C., H. E. Whiteley, and J. I. Everitt. “Preneoplastic and neoplastic lesions of rat hereditary renal cell tumors express markers of proximal and distal nephron.” Veterinary Pathology 32, no. 4 (July 1995): 379–86. https://doi.org/10.1177/030098589503200406.
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    • Everitt, J. I., D. C. Wolf, S. R. Howe, T. L. Goldsworthy, and C. Walker. “Rodent model of reproductive tract leiomyomata. Clinical and pathological features.” Am J Pathol 146, no. 6 (June 1995): 1556–67.
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    • Howe, S. R., J. I. Everitt, M. M. Gottardis, and C. Walker. “Estrogen/antiestrogen responsiveness in an in vivo/in vitro model for myometrial tumorigenesis.” Annals of the New York Academy of Sciences 761 (June 1995): 373–75. https://doi.org/10.1111/j.1749-6632.1995.tb31396.x.
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    • Howe, S. R., M. M. Gottardis, J. I. Everitt, T. L. Goldsworthy, D. C. Wolf, and C. Walker. “Rodent model of reproductive tract leiomyomata. Establishment and characterization of tumor-derived cell lines.” Am J Pathol 146, no. 6 (June 1995): 1568–79.
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    • Everitt, J., and W. Griffin. “Proposed IACUC guidelines for the review of rodent toxicology studies.” Contemp Top Lab Anim Sci 34, no. 3 (May 1995): 72–74.
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    • Horesovsky, G., L. Recio, J. Everitt, T. Goldsworthy, D. C. Wolf, and C. Walker. “p53 status in spontaneous and dimethylnitrosamine-induced renal cell tumors from rats.” Mol Carcinog 12, no. 4 (April 1995): 236–40. https://doi.org/10.1002/mc.2940120408.
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    • Walker, C., J. Everitt, P. C. Ferriola, W. Stewart, J. Mangum, and E. Bermudez. “Autocrine growth stimulation by transforming growth factor alpha in asbestos-transformed rat mesothelial cells.” Cancer Res 55, no. 3 (February 1, 1995): 530–36.
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    • Cattley, R. C., J. I. Everitt, E. A. Gross, O. R. Moss, T. E. Hamm, and J. A. Popp. “Erratum: Carcinogenicity and Toxicity of inhaled nitrobenzene in B6C3F1 mice and F344 and CD rats (Fundamental and Applied Toxicology (1994) Vol. 22, Number 3 (pp. 328-340)).” Fundamental and Applied Toxicology 25, no. 1 (January 1, 1995). https://doi.org/10.1006/faat.1995.1050.
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    • Everitt, J. I. “Mechanisms of fiber-induced diseases: implications for the safety evaluation of synthetic vitreous fibers.” Regul Toxicol Pharmacol 20, no. 3 Pt 2 (December 1994): S68–75.
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    • Horesovsky, G., J. Ginsler, J. Everitt, and C. Walker. “Increased susceptibility to in vitro transformation of cells carrying the Eker tumor susceptibility mutation.” Carcinogenesis 15, no. 10 (October 1994): 2183–87. https://doi.org/10.1093/carcin/15.10.2183.
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    • Hard, G. C., P. H. Long, J. W. Crissman, J. I. Everitt, B. L. Yano, and T. A. Bertram. “Atypical tubule hyperplasia and renal tubule tumors in conventional rats on 90-day toxicity studies.” Toxicologic Pathology 22, no. 5 (September 1994): 489–96. https://doi.org/10.1177/019262339402200503.
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    • Rutten, A. A., E. Bermudez, J. B. Mangum, B. A. Wong, O. R. Moss, and J. I. Everitt. “Mesothelial cell proliferation induced by intrapleural instillation of man-made fibers in rats and hamsters.” Fundam Appl Toxicol 23, no. 1 (July 1994): 107–16. https://doi.org/10.1006/faat.1994.1086.
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    • Walker, C., F. Rutten, X. Yuan, H. Pass, D. M. Mew, and J. Everitt. “Wilms' tumor suppressor gene expression in rat and human mesothelioma.” Cancer Res 54, no. 12 (June 15, 1994): 3101–6.
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    • Everitt, J. I., E. Bermudez, J. B. Mangum, B. Wong, O. R. Moss, D. Janszen, and A. A. Rutten. “Pleural lesions in Syrian golden hamsters and Fischer-344 rats following intrapleural instillation of man-made ceramic or glass fibers.” Toxicologic Pathology 22, no. 3 (May 1994): 229–36. https://doi.org/10.1177/019262339402200301.
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    • Cattley, R. C., J. I. Everitt, E. A. Gross, O. R. Moss, T. E. Hamm, and J. A. Popp. “Carcinogenicity and toxicity of inhaled nitrobenzene in B6C3F1 mice and F344 and CD rats.” Fundam Appl Toxicol 22, no. 3 (April 1994): 328–40. https://doi.org/10.1006/faat.1994.1039.
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    • Farris, G. M., J. I. Everitt, R. D. Irons, and J. A. Popp. “Carcinogenicity of inhaled benzene in CBA mice.” Fundam Appl Toxicol 20, no. 4 (May 1993): 503–7. https://doi.org/10.1006/faat.1993.1061.
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    • Satoh, H., P. W. Lamb, J. T. Dong, J. Everitt, C. Boreiko, M. Oshimura, and J. C. Barrett. “Suppression of tumorigenicity of A549 lung adenocarcinoma cells by human chromosomes 3 and 11 introduced via microcell-mediated chromosome transfer.” Molecular Carcinogenesis 7, no. 3 (January 1993): 157–64. https://doi.org/10.1002/mc.2940070306.
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    • Everitt, J. I., T. L. Goldsworthy, D. C. Wolf, and C. L. Walker. “Hereditary renal cell carcinoma in the Eker rat: a rodent familial cancer syndrome.” J Urol 148, no. 6 (December 1992): 1932–36. https://doi.org/10.1016/s0022-5347(17)37087-8.
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    • Kinnula, V. L., J. I. Everitt, J. B. Mangum, L. Y. Chang, and J. D. Crapo. “Antioxidant defense mechanisms in cultured pleural mesothelial cells.” Am J Respir Cell Mol Biol 7, no. 1 (July 1992): 95–103. https://doi.org/10.1165/ajrcmb/7.1.95.
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    • Walker, C., T. L. Goldsworthy, D. C. Wolf, and J. Everitt. “Predisposition to renal cell carcinoma due to alteration of a cancer susceptibility gene.” Science (New York, N.Y.) 255, no. 5052 (March 1992): 1693–95. https://doi.org/10.1126/science.1553556.
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    • Walker, C., E. Bermudez, W. Stewart, J. Bonner, C. J. Molloy, and J. Everitt. “Characterization of platelet-derived growth factor and platelet-derived growth factor receptor expression in asbestos-induced rat mesothelioma.” Cancer Res 52, no. 2 (January 15, 1992): 301–6.
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    • KINNULA, V. L., L. CHANG, J. I. EVERITT, and J. D. CRAPO. “OXIDANTS AND ANTIOXIDANTS IN ALVEOLAR EPITHELIAL TYPE-II CELLS - INSITU, FRESHLY ISOLATED, AND CULTURED-CELLS.” American Journal of Physiology 262, no. 1 (January 1, 1992): L69–77.
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    • Kinnula, V. L., L. Chang, J. I. Everitt, and J. D. Crapo. “Oxidants and antioxidants in alveolar epithelial type II cells: in situ, freshly isolated, and cultured cells.” Am J Physiol 262, no. 1 Pt 1 (January 1992): L69–77. https://doi.org/10.1152/ajplung.1992.262.1.L69.
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    • Kinnula, V. L., L. Chang, J. I. Everitt, and J. D. Crapo. “Oxidants and antioxidants in alveolar epithelial type II cells: In situ, freshly isolated, and cultured cells.” American Journal of Physiology  Lung Cellular and Molecular Physiology 262, no. 1 6-1 (January 1, 1992).
    • Lacy, S. A., J. B. Mangum, and J. I. Everitt. “Cytochrome P-450- and glutathione-associated enzyme activities in freshly isolated enriched lung cell fractions from beta-naphthoflavone-treated male F344 rats.” Toxicology 73, no. 2 (1992): 147–60. https://doi.org/10.1016/0300-483x(92)90098-y.
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    • Walker, C., J. Everitt, and J. C. Barrett. “Possible cellular and molecular mechanisms for asbestos carcinogenicity.” Am J Ind Med 21, no. 2 (1992): 253–73. https://doi.org/10.1002/ajim.4700210214.
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    • Walker, C., L. Recio, K. Funaki, and J. Everitt. “Cytogenetic and molecular correlates between rodent and human renal cell carcinoma.” Prog Clin Biol Res 376 (1992): 289–302.
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    • Funaki, K., J. Everitt, M. Oshimura, J. J. Freed, A. G. Knudson, and C. Walker. “Hereditary renal cell carcinoma in the rat associated with nonrandom loss of chromosomes 5 and 6.” Cancer Res 51, no. 16 (August 15, 1991): 4415–22.
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    • Casanova, M., K. T. Morgan, W. H. Steinhagen, J. I. Everitt, J. A. Popp, and H. D. Heck. “Covalent binding of inhaled formaldehyde to DNA in the respiratory tract of rhesus monkeys: pharmacokinetics, rat-to-monkey interspecies scaling, and extrapolation to man.” Fundam Appl Toxicol 17, no. 2 (August 1991): 409–28. https://doi.org/10.1016/0272-0590(91)90230-2.
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    • Funaki, K., J. Everitt, E. Bermudez, and C. Walker. “Trisomy of rat chromosome 1 associated with mesothelial cell transformation.” Cancer Res 51, no. 15 (August 1, 1991): 4059–66.
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    • KINNULA, V. L., J. I. EVERITT, A. R. WHORTON, and J. D. CRAPO. “HYDROGEN-PEROXIDE PRODUCTION BY ALVEOLAR TYPE-II CELLS, ALVEOLAR MACROPHAGES, AND ENDOTHELIAL-CELLS.” American Journal of Physiology 261, no. 2 (August 1, 1991): L84–91.
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    • Kinnula, V. L., J. I. Everitt, A. R. Whorton, and J. D. Crapo. “Hydrogen peroxide production by alveolar type II cells, alveolar macrophages, and endothelial cells.” Am J Physiol 261, no. 2 Pt 1 (August 1991): L84–91. https://doi.org/10.1152/ajplung.1991.261.2.L84.
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    • Walker, C., J. Everitt, J. J. Freed, A. G. Knudson, and L. O. Whiteley. “Altered expression of transforming growth factor-alpha in hereditary rat renal cell carcinoma.” Cancer Res 51, no. 11 (June 1, 1991): 2973–78.
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    • Kinnula, V. L., J. I. Everitt, A. R. Whorton, and J. D. Crapo. “Hydrogen peroxide production by alveolar type II cells, alveolar macrophages, and endothelial cells.” American Journal of Physiology  Lung Cellular and Molecular Physiology 261, no. 2 5-1 (January 1, 1991).
    • Yoshitomi, K., J. I. Everitt, and G. A. Boorman. “Primary optic nerve meningiomas in F344 rats.” Veterinary Pathology 28, no. 1 (January 1991): 79–81. https://doi.org/10.1177/030098589102800111.
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    • Mangum, J. B., J. I. Everitt, J. C. Bonner, L. R. Moore, and A. R. Brody. “Co-culture of primary pulmonary cells to model alveolar injury and translocation of proteins.” In Vitro Cell Dev Biol 26, no. 12 (December 1990): 1135–43. https://doi.org/10.1007/bf02623690.
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    • Bermudez, E., J. Everitt, and C. Walker. “Expression of growth factor and growth factor receptor RNA in rat pleural mesothelial cells in culture.” Exp Cell Res 190, no. 1 (September 1990): 91–98. https://doi.org/10.1016/0014-4827(90)90148-4.
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    • Everitt, J. I., and C. B. Richter. “Infectious diseases of the upper respiratory tract: implications for toxicology studies.” Environ Health Perspect 85 (April 1990): 239–47. https://doi.org/10.1289/ehp.85-1568352.
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    • Dubielzig, R. R., J. Everitt, J. A. Shadduck, and D. M. Albert. “Clinical and morphologic features of post-traumatic ocular sarcomas in cats.” Veterinary Pathology 27, no. 1 (January 1990): 62–65. https://doi.org/10.1177/030098589002700111.
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    • Everitt, J. I., T. W. Hesterberg, and C. J. Boreiko. “The use of tracheal implants in toxicology and carcinogenesis research.” Toxicology 60, no. 1–2 (January 1990): 27–40. https://doi.org/10.1016/0300-483x(90)90160-i.
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    • Monticello, T. M., K. T. Morgan, J. I. Everitt, and J. A. Popp. “Effects of formaldehyde gas on the respiratory tract of rhesus monkeys. Pathology and cell proliferation.” Am J Pathol 134, no. 3 (March 1989): 515–27.
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    • Everitt, J. I., C. J. Boreiko, J. B. Mangum, J. T. Martin, J. D. Iglehart, and T. W. Hesterberg. “Development of a tracheal implant xenograft model to expose human bronchial epithelial cells to toxic gases.” Toxicologic Pathology 17, no. 3 (January 1989): 465–73. https://doi.org/10.1177/019262338901700301.
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    • Everitt, J. I., P. W. Ross, and T. W. Davis. “Urologic syndrome associated with wire caging in AKR mice.” Lab Anim Sci 38, no. 5 (October 1988): 609–11.
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    • Casanova, M., H. D. Heck, J. I. Everitt, W. W. Harrington, and J. A. Popp. “Formaldehyde concentrations in the blood of rhesus monkeys after inhalation exposure.” Food and Chemical Toxicology : An International Journal Published for the British Industrial Biological Research Association 26, no. 8 (August 1988): 715–16. https://doi.org/10.1016/0278-6915(88)90071-3.
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    • Everitt, J. I., P. W. Ross, D. A. Neptun, and J. B. Mangum. “Effect of a purified diet on dystrophic cardiac calcinosis in mice.” Lab Anim Sci 38, no. 4 (August 1988): 426–29.
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    • Ross, P. W., and J. I. Everitt. “A nylon ball device for primate environmental enrichment.” Lab Anim Sci 38, no. 4 (August 1988): 481–83.
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    • Everitt, J. I., L. M. Olson, J. B. Mangum, and W. J. Visek. “High mortality with severe dystrophic cardiac calcinosis in C3H/OUJ mice fed high fat purified diets.” Veterinary Pathology 25, no. 2 (March 1988): 113–18. https://doi.org/10.1177/030098588802500202.
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    • Hesterberg, T. W., C. J. Boreiko, S. C. Maness, J. D. Iglehart, J. B. Mangum, and J. I. Everitt. “Carcinogen-induced unscheduled DNA synthesis in xenotransplanted human tracheobronchial epithelium: comparison with rat tracheal epithelium.” Carcinogenesis 9, no. 3 (March 1988): 467–72. https://doi.org/10.1093/carcin/9.3.467.
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    • Whiteley, H. E., J. I. Everitt, I. Kakoma, M. A. James, and M. Ristic. “Pathologic changes associated with fatal Plasmodium falciparum infection in the Bolivian squirrel monkey (Saimiri sciureus boliviensis).” Am J Trop Med Hyg 37, no. 1 (July 1987): 1–8. https://doi.org/10.4269/ajtmh.1987.37.1.
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    • Olson, L. M., S. K. Clinton, J. I. Everitt, P. V. Johnston, and W. J. Visek. “Lymphocyte activation, cell-mediated cytotoxicity and their relationship to dietary fat-enhanced mammary tumorigenesis in C3H/OUJ mice.” J Nutr 117, no. 5 (May 1987): 955–63. https://doi.org/10.1093/jn/117.5.955.
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    • Everitt, J. I., S. A. McLaughlin, and L. C. Helper. “Diagnostic exercise: eye lesions in rats.” Lab Anim Sci 37, no. 2 (April 1987): 203–4.
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    • Hooser, S. B., V. R. Beasley, and J. I. Everitt. “Effects of an insecticidal dip containing d-limonene in the cat.” J Am Vet Med Assoc 189, no. 8 (October 15, 1986): 905–8.
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    • Sundberg, J. P., and J. I. Everitt. “Diagnostic exercise: lingual growths in rabbits.” Lab Anim Sci 36, no. 5 (October 1986): 499–500.
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    • Everitt, J. I., J. A. Shadduck, C. Steinkamp, and G. Clabaugh. “Experimental Babesia bovis infection in Holstein calves.” Veterinary Pathology 23, no. 5 (September 1986): 556–62. https://doi.org/10.1177/030098588602300503.
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    • Zachary, J. F., D. P. O’Brien, B. W. Ingles, J. I. Everitt, and A. J. Parker. “Multicentric nerve sheath fibrosarcomas of multiple cranial nerve roots in two dogs.” J Am Vet Med Assoc 188, no. 7 (April 1, 1986): 723–26.
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    • Gelberg, H. B., J. F. Zachary, J. I. Everitt, R. C. Jensen, and D. L. Smetzer. “Sudden death in training and racing Thoroughbred horses.” J Am Vet Med Assoc 187, no. 12 (December 15, 1985): 1354–56.
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    • Shadduck, J. A., J. Everitt, and P. Bay. “Use of in vitro cytotoxicity to rank ocular irritation of six surfactants.” Alternative Methods in Toxicology. 3 (January 1985): 641–49.
    • Shamis, L. D., J. I. Everitt, and G. J. Baker. “Lymphosarcoma as the cause of ataxia in a horse.” J Am Vet Med Assoc 184, no. 12 (June 15, 1984): 1517–18.
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    • Everitt, J. I., A. W. Fetter, R. M. Kenney, and M. A. Della-Ferra. “Porcine necrotizing staphylococcal endometritis.” Veterinary Pathology 18, no. 1 (January 1981): 125–27. https://doi.org/10.1177/030098588101800116.
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    • Schafer, T. W., M. Lieberman, J. Everitt, and P. Came. “Cutaneous herpes simplex virus infection of guinea pigs as a model for antiviral chemotherapy.” Annals of the New York Academy of Sciences 284 (March 1977): 624–31. https://doi.org/10.1111/j.1749-6632.1977.tb21996.x.
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  • Book Sections

    • Fillman-Holliday, D., and J. Everitt. “Animal Care and Use in Toxicity Testing.” In Comprehensive Toxicology: Third Edition, 9–15:75–94, 2018. https://doi.org/10.1016/B978-0-12-801238-3.01947-4.
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    • Everitt, J. I., and R. Adler. “Issues in Laboratory Animal Science.” In Haschek and Rousseaux’s Handbook of Toxicologic Pathology, 619–40, 2013. https://doi.org/10.1016/B978-0-12-415759-0.00020-0.
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    • Fillman-Holliday, D., and J. Everitt. “Animal Care and Use in Toxicity Testing.” In Comprehensive Toxicology, Second Edition, 3:97–115, 2010. https://doi.org/10.1016/B978-0-08-046884-6.00313-4.
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    • Boorman, G. A., and J. I. Everitt. “Neoplastic Disease.” In The Laboratory Rat, 479–511, 2006. https://doi.org/10.1016/B978-012074903-4/50017-0.
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    • Everitt, J. I., and E. A. Gross. “Euthanasia and Necropsy.” In The Laboratory Rat, 665–78, 2006. https://doi.org/10.1016/B978-012074903-4/50023-6.
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  • Conference Papers

    • Han, Sang-oh, Songtao Li, Jeffrey I. Everitt, and Dwight D. Koeberl. “Salmeterol with Liver Depot Gene Therapy Reversed Biochemical and Autophagic Abnormalities of Skeletal Muscle in Pompe Disease.” In Molecular Therapy, 27:16–16. CELL PRESS, 2019.
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    • Brooks, Elizabeth D., Dustin J. Landau, Jeffrey I. Everitt, Talmage T. Brown, Kylie M. Grady, Lauren Waskowicz, Cameron R. Bass, et al. “Long-term complications of glycogen storage disease type Ia in the canine model treated with gene replacement therapy.” In J Inherit Metab Dis, 41:965–76, 2018. https://doi.org/10.1007/s10545-018-0223-y.
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    • Hext, P. M., D. B. Warheit, J. Mangum, B. Asgharian, B. Wong, E. Bermudez, and J. Everitt. “Comparison of the pulmonary responses to inhaled pigmentary and ultrafine titanium dioxide particles in the rat, mouse and hamster.” In Annals of Occupational Hygiene, 46:191–96, 2002. https://doi.org/10.1093/annhyg/46.suppl-1.191.
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    • Everitt, J. I., J. B. Mangum, E. Bermudez, B. A. Wong, B. Asgharian, E. E. Reverdy, P. M. Hext, and D. B. Warheit. “Comparison of selected pulmonary responses of rats, mice, and Syrian golden hamsters to inhaled pigmentary titanium dioxide.” In Inhalation Toxicology, 12:275–82, 2000.
    • Reverdy, E. E., E. Bermudez, J. B. Mangum, B. Asgharian, B. Wong, and J. I. Everitt. “Protein carbonyls in bronchoalveolar lavage fluid in mice, rats, and hamsters following inhalation of pigmentary titanium dioxide particles.” In Inhalation Toxicology, 12:283–89, 2000.
    • Hesterberg, T. W., C. Axten, E. E. McConnell, G. Oberdorster, J. Everitt, W. C. Miiller, J. Chevalier, G. R. Chase, and P. Thevenaz. “Chronic Inhalation Study of Fiber Glass and Amosite Asbestos in Hamsters: Twelve-Month Preliminary Results.” In Environmental Health Perspectives, 105:1223–1223. JSTOR, 1997. https://doi.org/10.2307/3433537.
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    • EVERITT, J. I. “MECHANISMS OF FIBER-INDUCED DISEASES - IMPLICATIONS FOR THE SAFETY EVALUATION OF SYNTHETIC VITREOUS FIBERS.” In Regulatory Toxicology and Pharmacology, 20:S68–75. ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, 1994.
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    • Everitt, J. I. “Mechanisms of fiber-induced diseases: Implications for the safety evaluation of synthetic vitreous fibers.” In Regulatory Toxicology and Pharmacology, Vol. 20, 1994.
    • Walker, C., E. Bermudez, J. Bonner, and J. Everitt. “Species-specific PDGF expression in mesothelioma.” In European Respiratory Review, 3:153–55, 1993.
    • HESTERBERG, T. W., C. J. BOREIKO, S. C. MANESS, J. B. MANGUM, J. D. IGLEHART, and J. I. EVERITT. “UNSCHEDULED DNA-SYNTHESIS (UDS) IN XENOGRAFTS CONTAINING RAT OR HUMAN RESPIRATORY EPITHELIAL-CELLS.” In Proceedings of the American Association for Cancer Research, 28:114–114. AMER ASSOC CANCER RESEARCH, 1987.
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• Teaching & Mentoring
• 

  Recent Courses

  • PATHOL 735S: Animal Models in Translational Research 2020
  • PATHOL 786: Translational Aspects of Pathobiology 2020

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