Overview
I divide my time between clinic and the laboratory. In clinic I focus primarily on fetal and neonatal patients with genetic disorders, brain malformations, prematurity, perinatal brain injury, and seizures. In the lab, I use a toolbox of mouse genetics, single-cell transcriptomics, and cell culture to study how cortical neurons change in response to perinatal brain injury and genetic neurodevelopmental disorders.
Current Appointments & Affiliations
Assistant Professor of Pediatrics
·
2023 - Present
Pediatrics, Neurology,
Pediatrics
Member of the Duke Cancer Institute
·
2024 - Present
Duke Cancer Institute,
Institutes and Centers
In the News
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Recent Publications
Pathogenic variants associated with speech/cognitive delay and seizures affect genes with expression biases in excitatory neurons and microglia in developing human cortex.
Preprint · July 2, 2024 Featured Publication Full text Link to item CiteSystematic, prospective collection of placental specimens is crucial for future studies on the maternal-placental-fetal triad in neonatal encephalopathy
Journal Article Pediatric Research · May 2024 Full text CiteMaternal Prenatal Use of Alcohol, Tobacco, and Illicit Drugs and Associations with Childhood Cancer Subtypes.
Journal Article Cancer Epidemiol Biomarkers Prev · March 1, 2024 BACKGROUND: The association between childhood cancer risk and maternal prenatal substance use/abuse remains uncertain due to modest sample sizes and heterogeneous study designs. METHODS: We surveyed parents of children with cancer regarding maternal gestat ... Full text Link to item CiteRecent Grants
Discovering the cell type basis of the IT projection system and its dysregulation after perinatal HIE
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2029Optimizing Gene Therapy for Respiratory Insufficiency in Duchenne Muscular Dystrophy
ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2028A programmable, cell type-specific, RNA-based tool to treat diffuse intrinsic pontine glioma (DIPG)
ResearchPrincipal Investigator · Awarded by B*Cured · 2023 - 2024View All Grants
Education, Training & Certifications
Cornell University, Weill Medical College ·
2016
MD./PhD.