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Jennifer Ann Rothman

Professor of Pediatrics
Pediatrics, Hematology-Oncology
385 Hanes House, Box 102382, Durham, NC 27710

Overview


Sickle Cell Disease
Bone Marrow Failure Syndromes
General Hematology

Current Appointments & Affiliations


Professor of Pediatrics · 2022 - Present Pediatrics, Hematology-Oncology, Pediatrics
Professor in Medicine · 2022 - Present Medicine, Hematology, Medicine

Recent Publications


Emapalumab use in malignancy-associated hemophagocytic lymphohistiocytosis in the United States: The REAL-HLH study.

Journal Article Blood Adv · December 3, 2025 Malignancy-associated hemophagocytic lymphohistiocytosis (mHLH), a hyperinflammatory syndrome, has poor prognosis and no standard therapy. Emapalumab, a fully human monoclonal antibody that neutralizes the proinflammatory cytokine interferon-gamma, is appr ... Full text Link to item Cite

Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment: The PINES Randomized Clinical Trial.

Journal Article JAMA · November 25, 2025 IMPORTANCE: Eltrombopag, a thrombopoietin receptor agonist, is approved by the US Food and Drug Administration for children with chronic immune thrombocytopenia. Efficacy of eltrombopag during the newly diagnosed phase of pediatric immune thrombocytopenia ... Full text Link to item Cite

Eltrombopag in combination with immunosuppressive therapy in pediatric severe aplastic anemia: phase 2 ESCALATE trial.

Journal Article Blood Adv · August 12, 2025 Severe aplastic anemia (SAA) is a rare, life-threatening disease with acquired pancytopenia and hypocellular bone marrow. ESCALATE evaluated eltrombopag in combination with immunosuppressive therapy (IST) in pediatric patients (aged 1 to <18 years) with re ... Full text Link to item Cite
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Recent Grants


Achieving Understanding of the Natural history of sickle cell Trait (AUNT)

ResearchCollaborating Investigator · Awarded by National Alliance for Sickle Cell Centers · 2024 - 2026

A Phase 3 Study of Eltrombopag vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia (ITP) in Children

Clinical TrialPrincipal Investigator · Awarded by Novartis Pharmaceuticals Corporation · 2019 - 2026

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Education, Training & Certifications


University of Medicine and Dentistry of New Jersey · 2003 M.D.