Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Residency, Internal Medicine, Duke University School of Medicine 2017 - 2021
  • M.D., Virginia Commonwealth University, School of Medicine 2017
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Regan, Jessica A., Jawan W. Abdulrahim, Nathan A. Bihlmeyer, Carol Haynes, Lydia Coulter Kwee, Manesh R. Patel, and Svati H. Shah. “Phenome-Wide Association Study of Severe COVID-19 Genetic Risk Variants.” J Am Heart Assoc 11, no. 5 (March 2022): e024004. https://doi.org/10.1161/JAHA.121.024004.
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    • Regan, Jessica A., Jawan Abdulrahim, Nathan Bihlmeyer, Carol Haynes, Lydia Coulter Kwee, Manesh Patel, and Svati H. Shah. “A Phenome Wide Association Study of Severe COVID-19 Genetic Risk Variants,” December 11, 2021. https://doi.org/10.1101/2021.12.08.21267433.
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    • Truby, Lauren K., Jessica A. Regan, Stephanie N. Giamberardino, Olga Ilkayeva, James Bain, Christopher B. Newgard, Christopher M. O’Connor, et al. “Circulating long chain acylcarnitines and outcomes in diabetic heart failure: an HF-ACTION clinical trial substudy.” Cardiovasc Diabetol 20, no. 1 (August 3, 2021): 161. https://doi.org/10.1186/s12933-021-01353-z.
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    • Regan, Jessica A., and Svati H. Shah. “Obesity Genomics and Metabolomics: a Nexus of Cardiometabolic Risk.” Curr Cardiol Rep 22, no. 12 (October 10, 2020): 174. https://doi.org/10.1007/s11886-020-01422-x.
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    • Konhilas, John P., Jessica N. Sanchez, Jessica A. Regan, Eleni Constantopoulos, Marissa Lopez-Pier, Danielle K. Cannon, Rinku Skaria, et al. “Using 4-vinylcyclohexene diepoxide as a model of menopause for cardiovascular disease.” American Journal of Physiology. Heart and Circulatory Physiology 318, no. 6 (June 2020): H1461–73. https://doi.org/10.1152/ajpheart.00555.2019.
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    • Regan, Jessica A., Bryan Golubski, Elizabeth B. Gilbert, Brian Sullivan, Shannon J. McCall, and Suchita S. Sata. “Glycogenic Hepatopathy Causing Elevated Lactic Acid and Liver Enzymes.” Am J Med 133, no. 2 (February 2020): 191–94. https://doi.org/10.1016/j.amjmed.2019.07.018.
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    • Regan, Jessica A., Dalane W. Kitzman, Eric S. Leifer, William E. Kraus, Jerome L. Fleg, Daniel E. Forman, David J. Whellan, et al. “Impact of Age on Comorbidities and Outcomes in Heart Failure With Reduced Ejection Fraction.” Jacc Heart Fail 7, no. 12 (December 2019): 1056–65. https://doi.org/10.1016/j.jchf.2019.09.004.
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    • Buckley, Leo F., Salvatore Carbone, Cory R. Trankle, Justin M. Canada, Claudia Oddi Erdle, Jessica A. Regan, Michele M. Viscusi, et al. “Effect of Interleukin-1 Blockade on Left Ventricular Systolic Performance and Work: A Post Hoc Pooled Analysis of 2 Clinical Trials.” Journal of Cardiovascular Pharmacology 72, no. 1 (July 2018): 68–70. https://doi.org/10.1097/fjc.0000000000000591.
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    • Nijenkamp, Louise L. A. M., Ilse A. E. Bollen, Hannah G. van Velzen, Jessica A. Regan, Marjon van Slegtenhorst, Hans W. M. Niessen, Arend F. L. Schinkel, et al. “Sex Differences at the Time of Myectomy in Hypertrophic Cardiomyopathy.” Circulation. Heart Failure 11, no. 6 (June 2018): e004133. https://doi.org/10.1161/circheartfailure.117.004133.
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    • Van Tassell, Benjamin W., Justin Canada, Salvatore Carbone, Cory Trankle, Leo Buckley, Claudia Oddi Erdle, Nayef A. Abouzaki, et al. “Interleukin-1 Blockade in Recently Decompensated Systolic Heart Failure: Results From REDHART (Recently Decompensated Heart Failure Anakinra Response Trial).” Circulation. Heart Failure 10, no. 11 (November 2017): e004373. https://doi.org/10.1161/circheartfailure.117.004373.
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    • Danilo, C. A., E. Constantopoulos, L. A. McKee, H. Chen, J. A. Regan, Y. Lipovka, S. Lahtinen, et al. “Bifidobacterium animalis subsp. lactis 420 mitigates the pathological impact of myocardial infarction in the mouse.” Beneficial Microbes 8, no. 2 (April 2017): 257–69. https://doi.org/10.3920/bm2016.0119.
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    • Najafi, Aref, Vasco Sequeira, Michiel Helmes, Ilse A. E. Bollen, Max Goebel, Jessica A. Regan, Lucie Carrier, Diederik W. D. Kuster, and Jolanda Van Der Velden. “Selective phosphorylation of PKA targets after β-adrenergic receptor stimulation impairs myofilament function in Mybpc3-targeted HCM mouse model.” Cardiovascular Research 110, no. 2 (May 2016): 200–214. https://doi.org/10.1093/cvr/cvw026.
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    • Regan, Jessica A., Adolfo Gabriele Mauro, Salvatore Carbone, Carlo Marchetti, Rabia Gill, Eleonora Mezzaroma, Juan Valle Raleigh, et al. “A mouse model of heart failure with preserved ejection fraction due to chronic infusion of a low subpressor dose of angiotensin II.” American Journal of Physiology. Heart and Circulatory Physiology 309, no. 5 (September 2015): H771–78. https://doi.org/10.1152/ajpheart.00282.2015.
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    • Konhilas, John P., Hao Chen, Elizabeth Luczak, Laurel A. McKee, Jessica Regan, Peter A. Watson, Brian L. Stauffer, et al. “Diet and sex modify exercise and cardiac adaptation in the mouse.” American Journal of Physiology. Heart and Circulatory Physiology 308, no. 2 (January 2015): H135–45. https://doi.org/10.1152/ajpheart.00532.2014.
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    • Haenchen, Steven D., Elizabeth T. Jacobs, Kristin N. Bratton, Aubri S. Carman, Eyal Oren, Heidi L. Pottinger, Jessica A. Regan, and Kacey C. Ernst. “Perceptions of personal belief vaccine exemption policy: a survey of Arizona vaccine providers.” Vaccine 32, no. 29 (June 2014): 3630–35. https://doi.org/10.1016/j.vaccine.2014.04.081.
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    • Chen, H., J. N. Perez, E. Constantopoulos, L. McKee, J. Regan, P. B. Hoyer, H. L. Brooks, and J. Konhilas. “A method to study the impact of chemically-induced ovarian failure on exercise capacity and cardiac adaptation in mice.” Journal of Visualized Experiments, no. 86 (April 7, 2014). https://doi.org/10.3791/51083.
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    • Sequeira, Vasco, Louise L. A. M. Nijenkamp, Jessica A. Regan, and Jolanda van der Velden. “The physiological role of cardiac cytoskeleton and its alterations in heart failure.” Biochimica Et Biophysica Acta 1838, no. 2 (February 2014): 700–722. https://doi.org/10.1016/j.bbamem.2013.07.011.
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    • Chen, H., H. Hwang, L. A. K. McKee, J. N. Perez, J. A. Regan, E. Constantopoulos, B. LaFleur, and J. P. Konhilas. “Temporal and morphological impact of pressure overload in transgenic FHC mice.” Frontiers in Physiology 4 AUG (September 30, 2013). https://doi.org/10.3389/fphys.2013.00205.
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    • McKee, Laurel A. K., Hao Chen, Jessica A. Regan, Samantha M. Behunin, Jeffery W. Walker, John S. Walker, and John P. Konhilas. “Sexually dimorphic myofilament function and cardiac troponin I phosphospecies distribution in hypertrophic cardiomyopathy mice.” Archives of Biochemistry and Biophysics 535, no. 1 (July 2013): 39–48. https://doi.org/10.1016/j.abb.2012.12.023.
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    • Perez, Jessica N., Hao Chen, Jessica A. Regan, Ashlie Emert, Eleni Constantopoulos, Melissa Lynn, and John P. Konhilas. “Effects of chemically induced ovarian failure on voluntary wheel-running exercise and cardiac adaptation in mice.” Comparative Medicine 63, no. 3 (June 2013): 233–43.
    • Sequeira, Vasco, Paul J. M. Wijnker, Louise L. A. M. Nijenkamp, Diederik W. D. Kuster, Aref Najafi, E Rosalie Witjas-Paalberends, Jessica A. Regan, et al. “Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations.” Circulation Research 112, no. 11 (May 2013): 1491–1505. https://doi.org/10.1161/circresaha.111.300436.
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