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Jessica McCann

Research Associate, Senior
Molecular Genetics and Microbiology
340 CARL Bldg, Box 3551, Durham, NC 27710

Research Interests


I am interested in how bacteria influence early life development of the immune system in animals and people. My love for host-microbe interactions began during an undergrad research semester at the Marine Biological Laboratory in Woods Hole, MA, where I worked with Dr. Ned Ruby studying the squid symbiont Vibrio fischeri. I completed my masters with Dr. Ruby in Hawaii, and then moved to NC with my family to do my PhD with Dr. Miriam Braunstein at UNC Chapel Hill studying protein secretion in Mycobacterium tuberculosis. After a finishing a postdoc with Dr. Joe St. Geme and Dr. Patrick Seed examining the effect of early life exposure to bacteria on development of allergy and asthma, I am now a research associate in the Rawls lab. I work with Dr. Rawls and a group of scientists and clinicians at Duke and Northwestern University studying gut bacteria that may contribute to obesity in adolescents.

Selected Grants


Microbial regulation of intestinal epithelial gene expression

ResearchSenior Research Associate · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2028

Genetic determinants of Bacteroides vulgatus colonization fitness and host inflammatory responses

ResearchSenior Research Associate · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2023 - 2027

MICROBIAL SUCCESSION AND ADAPTIVE IMMUNE RESPONSES IN THE PREMATURE INFANT

ResearchPostdoctoral Associate · Awarded by National Institutes of Health · 2014 - 2017

Biology of the HMW1 and HMW2 Adhesins of H. Infuenzae

ResearchPostdoctoral Associate · Awarded by Children's Hospital of Philadelphia · 2013 - 2014