Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Research Fellow, Division of Tumor Immunology, Pathology, Dana-Farber Cancer Institute 1987 - 1988
  • Clinical Fellow, Pediatric Infectious Diseases and Immunology, Pediatrics, University of Florida, College of Medicine 1985 - 1987
  • Pediatric Chief Resident, Pediatrics, University of Florida, College of Medicine 1984 - 1985
  • Pediatric Internship and Residency, Pediatrics, University of Florida, College of Medicine 1981 - 1984
  • M.D., University of Tennessee Health Science Center 1981
• 

  Duke Appointment History

  • Instructor, Temporary in the Department of Pediatrics, Pediatrics, Allergy and Immunology, Pediatrics 2013 - 2014
• Research
• 

  Selected Grants

  • Duke Center for Advancement of Child Health (CAtCH). awarded by National Institutes of Health 2021 - 2026
  • Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2025
  • Duke Resident Physician-Scientist Program - NIAID awarded by National Institutes of Health 2018 - 2022
  • Consequences of marijuana use on inflammatory pathways in HIV-infected youth awarded by National Institutes of Health 2017 - 2022
  • Impact of maternal HIV infection on immune priming of their uninfected infants awarded by National Institutes of Health 2020 - 2022
  • Phase IV, Multicenter, Open-label Study to Evaluate the Safety and Pharmacokinetics of BIVIGAM® in Primary Immune Deficiency Disorders in Subjects Aged 2 to 16 awarded by ADMA Biologics 2020 - 2021
  • LOC-IMPAACT Leadership Group awarded by Johns Hopkins University 2020 - 2021
  • A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Mavorixafor in Patients with WHIM Syndrome with Open-Label Extension awarded by X4 Pharmaceuticals 2020 - 2021
  • Research Training in Allergy and Clinical Immunology awarded by National Institutes of Health 2000 - 2021
  • LOC-IMPAACT Leadership Group awarded by Johns Hopkins University 2014 - 2020
  • A Phase 3, Multinational, Multicenter, Open-Label Study of the Safety, Tolerability, Efficacy, and Pharmacokinetics of ProMetic BioTherapeutics Immune Globulin Intravenous (Human) 10% in Adults and Children with Primary Immunodeficiency Diseases. awarded by ProMetic Life Sciences Inc. 2017 - 2020
  • Efficacy, Safety, Tolerability, Immunogenicity and Pharmacokinetic Evaluation of HYQVIA in Pediatric Subjects with Primary Immunodeficiency Diseases awarded by Baxalta, Inc. 2019 - 2020
  • Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiences awarded by Jeffrey Modell Foundation 2016 - 2019
  • ATN 071, Neurocognitive Assessment in Youth Initiating HAART, and its sub-study ATN 101, Assessment of Inflammatory Markers Associated with Neurocognitive Impairment in HIV-infected Adolescents awarded by University of North Carolina - Chapel Hill 2016 - 2019
  • An open-label, multi-center study to evaluate the 1 safety and phannacokinetics of IGSC 20% . administered for 6 months in subjects with primary immunodeficiency awarded by Grifols USA, LLC 2016 - 2019
  • Effect of breast feeding on immunologic priming in young infants awarded by National Institutes of Health 2012 - 2018
  • Office of AIDS Research Strategic Initiative to Develop and Overarching Research Agenda for Children and Youth awarded by Johns Hopkins University 2017
  • ATN Coordinating Center awarded by University of Alabama at Birmingham 2014 - 2017
  • Substance Use and Immunity in HIV+ Adolescents by Systems Biology awarded by University of Florida 2014 - 2016
  • Asthma Clinical Research Center of the American Lung Association awarded by American Lung Association 2009 - 2016
  • Substance Abuse and Immunity in HIV+ Adolescents by Systems Biology awarded by University of Florida 2014 - 2015
  • ATN Coordinating Center awarded by University of Alabama 2013 - 2014
• 

  External Relationships

  • argenx US, Inc
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Baloh, Carolyn H., Samiksha A. Borkar, Kai-Fen Chang, Jiqiang Yao, Michael S. Hershfield, Suhag H. Parikh, Donald B. Kohn, Maureen M. Goodenow, John W. Sleasman, and Li Yin. “Normal IgH Repertoire Diversity in an Infant with ADA Deficiency After Gene Therapy.” J Clin Immunol, June 28, 2021. https://doi.org/10.1007/s10875-021-01034-2.
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    • Kohn, Jordan N., Matthew Shane Loop, Julie J. Kim-Chang, Patricia A. Garvie, John W. Sleasman, Bernard Fischer, H Jonathon Rendina, Steven Paul Woods, Sharon L. Nichols, and Suzi Hong. “Trajectories of Depressive Symptoms, Neurocognitive Function, and Viral Suppression With Antiretroviral Therapy Among Youth With HIV Over 36 months.” J Acquir Immune Defic Syndr 87, no. 2 (June 1, 2021): 851–59. https://doi.org/10.1097/QAI.0000000000002653.
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    • Tao, Huishan, Yun Pan, Shuai Chu, Lei Li, Jinhai Xie, Peng Wang, Shimeng Zhang, Srija Reddy, John W. Sleasman, and Xiao-Ping Zhong. “Differential controls of MAIT cell effector polarization by mTORC1/mTORC2 via integrating cytokine and costimulatory signals.” Nat Commun 12, no. 1 (April 1, 2021): 2029. https://doi.org/10.1038/s41467-021-22162-8.
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    • Crayle, Jesse, Mai Elmallah, John Sleasman, and Richard Bedlack. “Total serum immunoglobulin A in ALS.” Amyotroph Lateral Scler Frontotemporal Degener 22, no. 1–2 (February 2021): 61–65. https://doi.org/10.1080/21678421.2020.1790608.
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    • Tao, Huishan, Lei Li, Nan-Shih Liao, Kimberly S. Schluns, Shirley Luckhart, John W. Sleasman, and Xiao-Ping Zhong. “Thymic Epithelial Cell-Derived IL-15 and IL-15 Receptor α Chain Foster Local Environment for Type 1 Innate Like T Cell Development.” Front Immunol 12 (2021): 623280. https://doi.org/10.3389/fimmu.2021.623280.
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    • Zhang, Shimeng, Lei Li, Danli Xie, Srija Reddy, John W. Sleasman, Li Ma, and Xiao-Ping Zhong. “Regulation of Intrinsic and Bystander T Follicular Helper Cell Differentiation and Autoimmunity by Tsc1.” Front Immunol 12 (2021): 620437. https://doi.org/10.3389/fimmu.2021.620437.
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    • Xie, Danli, Shimeng Zhang, Pengcheng Chen, Wenhai Deng, Yun Pan, Jinhai Xie, Jinli Wang, Bryce Liao, John W. Sleasman, and Xiao-Ping Zhong. “Negative control of diacylglycerol kinase ζ-mediated inhibition of T cell receptor signaling by nuclear sequestration in mice.” Eur J Immunol 50, no. 11 (November 2020): 1729–45. https://doi.org/10.1002/eji.201948442.
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    • Desai, Ankit K., Carolyn H. Baloh, John W. Sleasman, Amy S. Rosenberg, and Priya S. Kishnani. “Benefits of Prophylactic Short-Course Immune Tolerance Induction in Patients With Infantile Pompe Disease: Demonstration of Long-Term Safety and Efficacy in an Expanded Cohort.” Front Immunol 11 (2020): 1727. https://doi.org/10.3389/fimmu.2020.01727.
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    • Geier, Christoph B., Jocelyn R. Farmer, Zsofia Foldvari, Boglarka Ujhazi, Jolanda Steininger, John W. Sleasman, Suhag Parikh, et al. “Vasculitis as a Major Morbidity Factor in Patients With Partial RAG Deficiency.” Front Immunol 11 (2020): 574738. https://doi.org/10.3389/fimmu.2020.574738.
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    • Sleasman, John W., William R. Lumry, Iftikhar Hussain, H James Wedner, James B. Harris, Kecia L. Courtney, Elsa Mondou, Jiang Lin, and Mark R. Stein. “Immune globulin subcutaneous, human - klhw 20% for primary humoral immunodeficiency: an open-label, Phase III study.” Immunotherapy 11, no. 16 (November 2019): 1371–86. https://doi.org/10.2217/imt-2019-0159.
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    • Bosticardo, Marita, Yasuhiro Yamazaki, Jennifer Cowan, Giuliana Giardino, Cristina Corsino, Giulia Scalia, Rosaria Prencipe, et al. “Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis.” Am J Hum Genet 105, no. 3 (September 5, 2019): 549–61. https://doi.org/10.1016/j.ajhg.2019.07.014.
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    • Kim-Chang, Julie J., Kevin Donovan, Matthew Shane Loop, Suzi Hong, Bernard Fischer, Guglielmo Venturi, Patricia A. Garvie, et al. “Higher soluble CD14 levels are associated with lower visuospatial memory performance in Youth with HIV (YWH).” Aids, September 2, 2019. https://doi.org/10.1097/QAD.0000000000002371.
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    • Kim-Chang, Julie J., Lorena Wilson, Cliburn Chan, Bernard Fischer, Guglielmo Venturi, Maureen M. Goodenow, Grace Aldrovandi, Thomas J. Weber, John W. Sleasman, and John W. Adolescent Medicine Trials Network for HIV/AIDS Interventions. “Tenofovir Has Minimal Effect on Biomarkers of Bone Health in Youth with HIV Receiving Initial Antiretroviral Therapy.” Aids Res Hum Retroviruses 35, no. 8 (August 2019): 746–54. https://doi.org/10.1089/AID.2018.0270.
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    • Farmer, Jocelyn R., Zsofia Foldvari, Boglarka Ujhazi, Suk See De Ravin, Karin Chen, Jack J. H. Bleesing, Catharina Schuetz, et al. “Outcomes and Treatment Strategies for Autoimmunity and Hyperinflammation in Patients with RAG Deficiency.” J Allergy Clin Immunol Pract 7, no. 6 (July 2019): 1970-1985.e4. https://doi.org/10.1016/j.jaip.2019.02.038.
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    • Steinbach, William J., Daniel K. Benjamin, and John W. Sleasman. “Funding Pediatric Subspecialty Training: Are T32 Grants the Future?” J Pediatr 202 (November 2018): 4-7.e1. https://doi.org/10.1016/j.jpeds.2018.08.035.
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    • Mullins, Tanya L Kowalczyk, Su X. Li, James Bethel, Maureen M. Goodenow, Stephanie Hudey, John W. Sleasman, and John W. Adolescent Medicine Trials Network for HIV AIDS Interventions. “Sexually transmitted infections and immune activation among HIV-infected but virally suppressed youth on antiretroviral therapy.” J Clin Virol 102 (May 2018): 7–11. https://doi.org/10.1016/j.jcv.2018.02.001.
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    • Williams, Julie C., Xinrui Zhang, Manju Karki, Yueh-Yun Chi, Shannon M. Wallet, Bret J. Rudy, Sharon L. Nichols, Maureen M. Goodenow, and John W. Sleasman. “Soluble CD14, CD163, and CD27 biomarkers distinguish ART-suppressed youth living with HIV from healthy controls.” J Leukoc Biol 103, no. 4 (April 2018): 671–80. https://doi.org/10.1002/JLB.3A0717-294RR.
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    • Appelberg, K Sofia, Mark A. Wallet, Jared P. Taylor, Melanie N. Cash, John W. Sleasman, and Maureen M. Goodenow. “HIV-1 Infection Primes Macrophages Through STAT Signaling to Promote Enhanced Inflammation and Viral Replication.” Aids Res Hum Retroviruses 33, no. 7 (July 2017): 690–702. https://doi.org/10.1089/AID.2016.0273.
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    • Pannaraj, Pia S., Fan Li, Chiara Cerini, Jeffrey M. Bender, Shangxin Yang, Adrienne Rollie, Helty Adisetiyo, et al. “Association Between Breast Milk Bacterial Communities and Establishment and Development of the Infant Gut Microbiome.” Jama Pediatr 171, no. 7 (July 1, 2017): 647–54. https://doi.org/10.1001/jamapediatrics.2017.0378.
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    • Kahn, Jessica A., Jiahong Xu, Bill G. Kapogiannis, and John W. Sleasman. “Brief Report: Antibody Responses to Quadrivalent HPV Vaccination in HIV-Infected Young Women as Measured by Total IgG and Competitive Luminex Immunoassay.” J Acquir Immune Defic Syndr 75, no. 2 (June 1, 2017): 241–45. https://doi.org/10.1097/QAI.0000000000001355.
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    • Louie, Raymond J., Queenie K-G Tan, Jennifer B. Gilner, R Curtis Rogers, Noelle Younge, Stephanie B. Wechsler, Marie T. McDonald, et al. “Novel pathogenic variants in FOXP3 in fetuses with echogenic bowel and skin desquamation identified by ultrasound.” Am J Med Genet A 173, no. 5 (May 2017): 1219–25. https://doi.org/10.1002/ajmg.a.38144.
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    • Morena, M Teresa de la, David Leonard, Troy R. Torgerson, Otavio Cabral-Marques, Mary Slatter, Asghar Aghamohammadi, Sharat Chandra, et al. “Long-term outcomes of 176 patients with X-linked hyper-IgM syndrome treated with or without hematopoietic cell transplantation.” J Allergy Clin Immunol 139, no. 4 (April 2017): 1282–92. https://doi.org/10.1016/j.jaci.2016.07.039.
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    • Kalampokis, Ioannis, Guglielmo M. Venturi, Jonathan C. Poe, Jeffrey A. Dvergsten, John W. Sleasman, and Thomas F. Tedder. “The Regulatory B Cell Compartment Expands Transiently During Childhood and Is Contracted in Children With Autoimmunity.” Arthritis Rheumatol 69, no. 1 (January 2017): 225–38. https://doi.org/10.1002/art.39820.
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    • Ballow, Mark, Paul J. Pinciaro, Timothy Craig, Gary Kleiner, James Moy, Hans D. Ochs, John Sleasman, and William Smits. “Flebogamma(®) 5 % DIF Intravenous Immunoglobulin for Replacement Therapy in Children with Primary Immunodeficiency Diseases.” J Clin Immunol 36, no. 6 (August 2016): 583–89. https://doi.org/10.1007/s10875-016-0303-4.
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    • Ruan, Alexandra, Nicole H. Tobin, Kathleen Mulligan, Adrienne Rollie, Fan Li, John Sleasman, and Grace M. Aldrovandi. “Brief Report: Macrophage Activation in HIV-Infected Adolescent Males Contributes to Differential Bone Loss by Sex: Adolescent Trials Network Study 021.” J Acquir Immune Defic Syndr 72, no. 4 (August 1, 2016): 372–75. https://doi.org/10.1097/QAI.0000000000000953.
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    • Nichols, Sharon L., James Bethel, Bill G. Kapogiannis, Tiandong Li, Steven P. Woods, E Doyle Patton, Weijia Ren, et al. “Antiretroviral treatment initiation does not differentially alter neurocognitive functioning over time in youth with behaviorally acquired HIV.” J Neurovirol 22, no. 2 (April 2016): 218–30. https://doi.org/10.1007/s13365-015-0389-0.
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    • Niebur, H. B., C. M. Duff, G. F. Shear, D. Nguyen, T. K. Alberdi, M. J. Dorsey, and J. W. Sleasman. “Efficacy and tolerability of 16% subcutaneous immunoglobulin compared with 20% subcutaneous immunoglobulin in primary antibody deficiency.” Clin Exp Immunol 181, no. 3 (September 2015): 441–50. https://doi.org/10.1111/cei.12623.
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    • Wallet, Mark A., Thomas W. Buford, Anna-Maria Joseph, Madhuri Sankuratri, Christiaan Leeuwenburgh, Marco Pahor, Todd Manini, John W. Sleasman, and Maureen M. Goodenow. “Increased inflammation but similar physical composition and function in older-aged, HIV-1 infected subjects.” Bmc Immunol 16 (July 24, 2015): 43. https://doi.org/10.1186/s12865-015-0106-z.
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    • Williams, J. C., T. W. Klein, B. A. Goldberger, J. W. Sleasman, N. Mackman, and M. M. Goodenow. “Δ⁹-Tetrahydrocannabinol (THC) enhances lipopolysaccharide-stimulated tissue factor in human monocytes and monocyte-derived microvesicles.” Journal of Inflammation (United Kingdom) 12, no. 1 (June 12, 2015). https://doi.org/10.1186/s12950-015-0084-1.
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    • Rudy, Bret J., Bill G. Kapogiannis, Carol Worrell, Kathleen Squires, James Bethel, Su Li, Craig M. Wilson, et al. “Immune Reconstitution but Persistent Activation After 48 Weeks of Antiretroviral Therapy in Youth With Pre-Therapy CD4 >350 in ATN 061.” J Acquir Immune Defic Syndr 69, no. 1 (May 1, 2015): 52–60. https://doi.org/10.1097/QAI.0000000000000549.
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    • Justice, Jeb M., John W. Sleasman, and Donald C. Lanza. “Recalcitrant rhinosinusitis, innate immunity, and mannose-binding lectin.” Ann Otol Rhinol Laryngol 124, no. 2 (February 2015): 102–6. https://doi.org/10.1177/0003489414543680.
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    • Kubiak, Catherine, Soma Jyonouchi, Caroline Kuo, Maria Garcia-Lloret, Morna J. Dorsey, John Sleasman, Arthur S. Zbrozek, and Elena E. Perez. “Fiscal implications of newborn screening in the diagnosis of severe combined immunodeficiency.” J Allergy Clin Immunol Pract 2, no. 6 (November 2014): 697–702. https://doi.org/10.1016/j.jaip.2014.05.013.
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    • Ladinsky, Hava T., Araceli Elizalde, Robyn Schickler, Paola B. Dees, Melissa L. Crenshaw, and John W. Sleasman. “Hypereosinophilic syndrome and hemimelia in a patient with chromosome 6p22.3 deletion.” Pediatr Allergy Immunol 25, no. 5 (August 2014): 500–503. https://doi.org/10.1111/pai.12213.
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    • Williams, Julie C., Sofia Appelberg, Bruce A. Goldberger, Thomas W. Klein, John W. Sleasman, and Maureen M. Goodenow. “Δ(9)-Tetrahydrocannabinol treatment during human monocyte differentiation reduces macrophage susceptibility to HIV-1 infection.” J Neuroimmune Pharmacol 9, no. 3 (June 2014): 369–79. https://doi.org/10.1007/s11481-014-9527-3.
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    • Routes, John, Mario Abinun, Waleed Al-Herz, Jacinta Bustamante, Antonio Condino-Neto, Maria Teresa De La Morena, Amos Etzioni, et al. “ICON: the early diagnosis of congenital immunodeficiencies.” J Clin Immunol 34, no. 4 (May 2014): 398–424. https://doi.org/10.1007/s10875-014-0003-x.
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    • Martinez-Lopez, Denise G., Nicholas T. Funderburg, Adam Cerissi, Reema Rifaie, Laura Aviles-Medina, Braulio J. Llorens-Bonilla, John Sleasman, and Angel A. Luciano. “Lipopolysaccharide and soluble CD14 in cord blood plasma are associated with prematurity and chorioamnionitis.” Pediatr Res 75, no. 1–1 (January 2014): 67–74. https://doi.org/10.1038/pr.2013.182.
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    • Nichols, Sharon L., Amanda Lowe, Xinrui Zhang, Patricia A. Garvie, Sarah Thornton, Bruce A. Goldberger, Wei Hou, Maureen M. Goodenow, and John W. Sleasman. “Concordance between self-reported substance use and toxicology among HIV-infected and uninfected at risk youth.” Drug Alcohol Depend 134 (January 1, 2014): 376–82. https://doi.org/10.1016/j.drugalcdep.2013.11.010.
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    • Sriaroon, Panida, Araceli Elizalde, Elena E. Perez, Jennifer W. Leiding, Grace M. Aldrovandi, and John W. Sleasman. “Psychrobacter immobilis septicemia in a boy with X-linked chronic granulomatous disease and fulminant hepatic failure.” J Clin Immunol 34, no. 1 (January 2014): 39–41. https://doi.org/10.1007/s10875-013-9961-7.
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    • Yin, L., W. Hou, L. Liu, Y. Cai, M. A. Wallet, B. P. Gardner, K. Chang, et al. “IgM repertoire biodiversity is reduced in HIV-1 infection and systemic lupus erythematosus.” Frontiers in Immunology 4, no. NOV (December 19, 2013). https://doi.org/10.3389/fimmu.2013.00373.
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    • Sanou, Missa P., Shannon R. Roff, Antony Mennella, John W. Sleasman, Mobeen H. Rathore, Janet K. Yamamoto, and Jay A. Levy. “Evolutionarily conserved epitopes on human immunodeficiency virus type 1 (HIV-1) and feline immunodeficiency virus reverse transcriptases detected by HIV-1-infected subjects.” J Virol 87, no. 18 (September 2013): 10004–15. https://doi.org/10.1128/JVI.00359-13.
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    • Berger, Melvin, Stephen Jolles, Jordan S. Orange, and John W. Sleasman. “Bioavailability of IgG administered by the subcutaneous route.” J Clin Immunol 33, no. 5 (July 2013): 984–90. https://doi.org/10.1007/s10875-013-9876-3.
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    • Syed, Salma S., Rula S. Balluz, Edmond K. Kabagambe, William A. Meyer, Susan Lukas, Craig M. Wilson, Bill G. Kapogiannis, Sharon A. Nachman, and John W. Sleasman. “Assessment of biomarkers of cardiovascular risk among HIV type 1-infected adolescents: role of soluble vascular cell adhesion molecule as an early indicator of endothelial inflammation.” Aids Res Hum Retroviruses 29, no. 3 (March 2013): 493–500. https://doi.org/10.1089/AID.2012.0086.
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    • Yin, Li, Li Liu, Yijun Sun, Wei Hou, Amanda C. Lowe, Brent P. Gardner, Marco Salemi, et al. “High-resolution deep sequencing reveals biodiversity, population structure, and persistence of HIV-1 quasispecies within host ecosystems.” Retrovirology 9 (December 17, 2012): 108. https://doi.org/10.1186/1742-4690-9-108.
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    • Wallet, Mark A., Caroline M. Reist, Julie C. Williams, Sofia Appelberg, Giorgio L. Guiulfo, Brent Gardner, John W. Sleasman, and Maureen M. Goodenow. “The HIV-1 protease inhibitor nelfinavir activates PP2 and inhibits MAPK signaling in macrophages: a pathway to reduce inflammation.” J Leukoc Biol 92, no. 4 (October 2012): 795–805. https://doi.org/10.1189/jlb.0911447.
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    • Mulligan, Kathleen, D Robert Harris, Patricia Emmanuel, Roger A. Fielding, Carol Worrell, Bill G. Kapogiannis, Dina Monte, et al. “Low bone mass in behaviorally HIV-infected young men on antiretroviral therapy: Adolescent Trials Network Study 021B.” Clin Infect Dis 55, no. 3 (August 2012): 461–68. https://doi.org/10.1093/cid/cis455.
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    • Agwu, Allison L., James Bethel, Lisa B. Hightow-Weidman, John W. Sleasman, Craig M. Wilson, Bret Rudy, Bill G. Kapogiannis, and Bill G. ATN 061 Team and the Adolescent Medicine Trials Network for HIV/AIDS Interventions. “Substantial multiclass transmitted drug resistance and drug-relevant polymorphisms among treatment-naïve behaviorally HIV-infected youth.” Aids Patient Care Stds 26, no. 4 (April 2012): 193–96. https://doi.org/10.1089/apc.2011.0420.
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    • Asante-Korang, Alfred, Jeffrey P. Jacobs, Jeremy Ringewald, Jennifer Carapellucci, Kristin Rosenberg, Daniel McKenna, Jorge McCormack, et al. “Management of children undergoing cardiac transplantation with high Panel Reactive Antibodies.” Cardiol Young 21 Suppl 2 (December 2011): 124–32. https://doi.org/10.1017/S1047951111001703.
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    • Haraguchi, Soichi, Sarah K. Ho, Matthew Morrow, Maureen M. Goodenow, and John W. Sleasman. “Developmental regulation of P-glycoprotein activity within thymocytes results in increased anti-HIV protease inhibitor activity.” J Leukoc Biol 90, no. 4 (October 2011): 653–60. https://doi.org/10.1189/jlb.0111-009.
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    • Jolles, S., and J. W. Sleasman. “Subcutaneous immunoglobulin replacement therapy with Hizentra, the first 20% SCIG preparation: a practical approach.” Adv Ther 28, no. 7 (July 2011): 521–33. https://doi.org/10.1007/s12325-011-0036-y.
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    • Orange, Jordan S., Joseph T. Glessner, Elena Resnick, Kathleen E. Sullivan, Mary Lucas, Berne Ferry, Cecilia E. Kim, et al. “Genome-wide association identifies diverse causes of common variable immunodeficiency.” J Allergy Clin Immunol 127, no. 6 (June 2011): 1360-7.e6. https://doi.org/10.1016/j.jaci.2011.02.039.
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    • Haraguchi, Soichi, Noorbibi K. Day, Nutthapong Tangsinmankong, and John W. Sleasman. “Profound reduction of invariant natural killer T cells in the peripheral blood of a patient with interleukin-1 receptor-associated kinase 4 deficiency.” Immunol Lett 132, no. 1–2 (August 16, 2010): 86–89. https://doi.org/10.1016/j.imlet.2010.04.011.
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    • Wallet, Mark A., Carina A. Rodriguez, Li Yin, Sara Saporta, Sasawan Chinratanapisit, Wei Hou, John W. Sleasman, and Maureen M. Goodenow. “Microbial translocation induces persistent macrophage activation unrelated to HIV-1 levels or T-cell activation following therapy.” Aids 24, no. 9 (June 1, 2010): 1281–90. https://doi.org/10.1097/QAD.0b013e328339e228.
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    • Sleasman, John W., Carla M. Duff, Theresa Dunaway, Mikhail A. Rojavin, and Mark R. Stein. “Tolerability of a new 10% liquid immunoglobulin for intravenous use, Privigen, at different infusion rates.” J Clin Immunol 30, no. 3 (May 2010): 442–48. https://doi.org/10.1007/s10875-010-9373-x.
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    • Mulligan, Kathleen, D Robert Harris, Dina Monte, Sonia Stoszek, Patricia Emmanuel, Dana S. Hardin, Bill G. Kapogiannis, et al. “Obesity and dyslipidemia in behaviorally HIV-infected young women: Adolescent Trials Network study 021.” Clin Infect Dis 50, no. 1 (January 1, 2010): 106–14. https://doi.org/10.1086/648728.
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    • Wallet, Mark A., Shannon M. Wallet, Giorgio Guiulfo, John W. Sleasman, and Maureen M. Goodenow. “IFNgamma primes macrophages for inflammatory activation by high molecular weight hyaluronan.” Cell Immunol 262, no. 2 (2010): 84–88. https://doi.org/10.1016/j.cellimm.2010.02.013.
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    • Wynn, J. L., M. A. Saxonhouse, and J. W. Sleasman. “Immunodeficiency diseases of the neonate,” January 1, 2010, 255–76. https://doi.org/10.1017/CBO9780511978135.017.
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    • Yin, Li, Zhong Chen Kou, Carina Rodriguez, Wei Hou, Maureen M. Goodenow, and John W. Sleasman. “Antiretroviral therapy restores diversity in the T-cell receptor Vbeta repertoire of CD4 T-cell subpopulations among human immunodeficiency virus type 1-infected children and adolescents.” Clin Vaccine Immunol 16, no. 9 (September 2009): 1293–1301. https://doi.org/10.1128/CVI.00074-09.
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    • Ho, Sarah K., Elena E. Perez, Stephanie L. Rose, Roxana M. Coman, Amanda C. Lowe, Wei Hou, Changxing Ma, et al. “Genetic determinants in HIV-1 Gag and Env V3 are related to viral response to combination antiretroviral therapy with a protease inhibitor.” Aids 23, no. 13 (August 24, 2009): 1631–40. https://doi.org/10.1097/QAD.0b013e32832e0599.
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    • Wasserman, Richard L., Joseph A. Church, Hans H. Peter, John W. Sleasman, Isaac Melamed, Mark R. Stein, Johann Bichler, and Johann IgPro10 in PID Study group. “Pharmacokinetics of a new 10% intravenous immunoglobulin in patients receiving replacement therapy for primary immunodeficiency.” Eur J Pharm Sci 37, no. 3–4 (June 28, 2009): 272–78. https://doi.org/10.1016/j.ejps.2009.02.014.
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    • Church, J. A., M. Borte, H. Taki, R. P. Nelson, J. W. Sleasman, A. P. Knutsen, E. Le Gall, M. Debre, and P. Kiessling. “Efficacy and safety of privigen in children and adolescents with primary immunodeficiency.” Pediatric Asthma, Allergy and Immunology 22, no. 2 (June 1, 2009): 53–61. https://doi.org/10.1089/pai.2009.0005.
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    • Rudy, Bret J., John Sleasman, Bill Kapogiannis, Craig M. Wilson, James Bethel, Leslie Serchuck, Sushma Ahmad, Coleen K. Cunningham, and Coleen K. Adolescent Trials Network for HIV/AIDS Interventions. “Short-cycle therapy in adolescents after continuous therapy with established viral suppression: the impact on viral load suppression.” Aids Res Hum Retroviruses 25, no. 6 (June 2009): 555–61. https://doi.org/10.1089/aid.2008.0203.
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    • Sleasman, J. W., B. L. Robbins, S. J. Cross, J. C. Lindsey, J. M. Kraimer, B. E. Heckman, H. L. Sprenger, et al. “Abacavir pharmacokinetics during chronic therapy in HIV-1-infected adolescents and young adults.” Clin Pharmacol Ther 85, no. 4 (April 2009): 394–401. https://doi.org/10.1038/clpt.2008.236.
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    • Malee, Kathleen, Paige L. Williams, Grace Montepiedra, Sharon Nichols, Patricia A. Sirois, Deborah Storm, John Farley, Betsy Kammerer, and Betsy PACTG 219C Team. “The role of cognitive functioning in medication adherence of children and adolescents with HIV infection.” J Pediatr Psychol 34, no. 2 (March 2009): 164–75. https://doi.org/10.1093/jpepsy/jsn068.
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    • Dorsey, Morna J., A. Petrovic, M. R. Morrow, L. J. Dishaw, and J. W. Sleasman. “FOXP3 expression following bone marrow transplantation for IPEX syndrome after reduced-intensity conditioning.” Immunol Res 44, no. 1–3 (2009): 179–84. https://doi.org/10.1007/s12026-009-8112-y.
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    • Ho, Sarah K., Roxana M. Coman, Joshua C. Bunger, Stephanie L. Rose, Patricia O’Brien, Isabel Munoz, Ben M. Dunn, John W. Sleasman, and Maureen M. Goodenow. “Drug-associated changes in amino acid residues in Gag p2, p7(NC), and p6(Gag)/p6(Pol) in human immunodeficiency virus type 1 (HIV-1) display a dominant effect on replicative fitness and drug response.” Virology 378, no. 2 (September 1, 2008): 272–81. https://doi.org/10.1016/j.virol.2008.05.029.
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    • Yin, Li, Carina A. Rodriguez, Wei Hou, Olivia Potter, Margaret J. Caplan, Maureen M. Goodenow, and John W. Sleasman. “Antiretroviral therapy corrects HIV-1-induced expansion of CD8+ CD45RA+ CD2-) CD11a(bright) activated T cells.” J Allergy Clin Immunol 122, no. 1 (July 2008): 166-172.e2. https://doi.org/10.1016/j.jaci.2008.04.029.
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    • Walsh, Catherine J., Stephanie R. Leggett, Kathryn Strohbehn, Richard H. Pierce, and John W. Sleasman. “Effects of in vitro brevetoxin exposure on apoptosis and cellular metabolism in a leukemic T cell line (Jurkat).” Mar Drugs 6, no. 2 (June 10, 2008): 291–307. https://doi.org/10.3390/md20080014.
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    • Brown, Joseph N., James J. Kohler, Carter R. Coberley, John W. Sleasman, and Maureen M. Goodenow. “HIV-1 activates macrophages independent of Toll-like receptors.” Plos One 3, no. 12 (2008): e3664. https://doi.org/10.1371/journal.pone.0003664.
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    • Rodriguez, Carina A., Sarah Koch, Maureen Goodenow, and John W. Sleasman. “Clinical implications of discordant viral and immune outcomes following protease inhibitor containing antiretroviral therapy for HIV-infected children.” Immunol Res 40, no. 3 (2008): 271–86. https://doi.org/10.1007/s12026-007-0031-1.
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    • Sanka, Madhurima, Nutthapong Tangsinmankong, Melissa Loscalzo, John W. Sleasman, and Morna J. Dorsey. “Complete DiGeorge syndrome associated with CHD7 mutation.” J Allergy Clin Immunol 120, no. 4 (October 2007): 952–54. https://doi.org/10.1016/j.jaci.2007.08.013.
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    • Salemi, Marco, Brant R. Burkhardt, Rebecca R. Gray, Guity Ghaffari, John W. Sleasman, and Maureen M. Goodenow. “Phylodynamics of HIV-1 in lymphoid and non-lymphoid tissues reveals a central role for the thymus in emergence of CXCR4-using quasispecies.” Plos One 2, no. 9 (September 26, 2007): e950. https://doi.org/10.1371/journal.pone.0000950.
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    • Pahwa, Savita, Petronella Muresan, John Sleasman, Terry Fenton, John Moye, Audra Deveikis, Diane Wara, Russ Van Dyke, and Russ Pediatric Aids Clinical Trials Study 402 team. “Phase I/II trial of intermittent subcutaneous IL-2 administration in pediatric patients with moderate immune suppression: results of Pediatric AIDS Clinical Trials Study 402.” J Allergy Clin Immunol 119, no. 6 (June 2007): 1538–41. https://doi.org/10.1016/j.jaci.2006.12.674.
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    • Kamchaisatian, Wasu, Watcharaphong Wanwatsuntikul, John W. Sleasman, and Nutthapong Tangsinmankong. “Validation of current joint American Academy of Allergy, Asthma & Immunology and American College of Allergy, Asthma and Immunology guidelines for antibody response to the 23-valent pneumococcal vaccine using a population of HIV-infected children.” J Allergy Clin Immunol 118, no. 6 (December 2006): 1336–41. https://doi.org/10.1016/j.jaci.2006.09.036.
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    • Lavi, Richard F., Wasu Kamchaisatian, John W. Sleasman, Diana P. Martin, Soichi Haraguchi, Noorbibi K. Day, and Nutthapong Tangsinmankong. “Thymic output markers indicate immune dysfunction in DiGeorge syndrome.” J Allergy Clin Immunol 118, no. 5 (November 2006): 1184–86. https://doi.org/10.1016/j.jaci.2006.07.052.
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    • Marhefka, Stephanie L., Vicki J. Tepper, John J. Farley, John W. Sleasman, and Claude Ann Mellins. “Brief report: assessing adherence to pediatric antiretroviral regimens using the 24-hour recall interview.” J Pediatr Psychol 31, no. 9 (October 2006): 989–94. https://doi.org/10.1093/jpepsy/jsj107.
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    • Haraguchi, Soichi, Noorbibi K. Day, Wasu Kamchaisatian, Macarena Beigier-Pompadre, Steffen Stenger, Nutthapong Tangsinmankong, John W. Sleasman, Salvatore V. Pizzo, and George J. Cianciolo. “LMP-420, a small-molecule inhibitor of TNF-alpha, reduces replication of HIV-1 and Mycobacterium tuberculosis in human cells.” Aids Res Ther 3 (March 31, 2006): 8. https://doi.org/10.1186/1742-6405-3-8.
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    • Ghaffari, Guity, Daniel L. Tuttle, Daniel Briggs, Brant R. Burkhardt, Deepa Bhatt, Warren A. Andiman, John W. Sleasman, and Maureen M. Goodenow. “Complex determinants in human immunodeficiency virus type 1 envelope gp120 mediate CXCR4-dependent infection of macrophages.” J Virol 79, no. 21 (November 2005): 13250–61. https://doi.org/10.1128/JVI.79.21.13250-13261.2005.
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    • Martin, Diana P., Nutthapong Tangsinmankong, John W. Sleasman, Noorbibi K. Day-Good, and Danita R. Wongchantara. “Acrodermatitis enteropathica-like eruption and food allergy.” Ann Allergy Asthma Immunol 94, no. 3 (March 2005): 398–401. https://doi.org/10.1016/S1081-1206(10)60994-5.
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    • Saxonhouse, M. A., and J. W. Sleasman. “Immunodeficiency diseases of the neonate,” January 1, 2005, 280–309. https://doi.org/10.1017/CBO9780511545306.014.
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    • Coberley, Carter R., James J. Kohler, Joseph N. Brown, Joseph T. Oshier, Henry V. Baker, Michael P. Popp, John W. Sleasman, and Maureen M. Goodenow. “Impact on genetic networks in human macrophages by a CCR5 strain of human immunodeficiency virus type 1.” J Virol 78, no. 21 (November 2004): 11477–86. https://doi.org/10.1128/JVI.78.21.11477-11486.2004.
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    • Ghaffari, Guity, Dominick J. Passalacqua, Jennifer L. Caicedo, Maureen M. Goodenow, and John W. Sleasman. “Two-year clinical and immune outcomes in human immunodeficiency virus-infected children who reconstitute CD4 T cells without control of viral replication after combination antiretroviral therapy.” Pediatrics 114, no. 5 (November 2004): e604–11. https://doi.org/10.1542/peds.2004-0274.
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    • Rucker, Rajivi P., Noorbibi K. Day, Robert A. Good, Wasu Kamchaisatian, Patricia Emmanuel, John W. Sleasman, Cathy Mayeski, Elmer Dinglasan, Soichi Haraguchi, and Nutthapong Tangsinmankong. “Effect of influenza virus vaccine on the expression of human immunodeficiency virus co-receptor CCR5.” Ann Allergy Asthma Immunol 93, no. 3 (September 2004): 272–76. https://doi.org/10.1016/S1081-1206(10)61500-1.
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    • Uphold, Constance R., Javier Maruenda, Hossein N. Yarandi, John W. Sleasman, and Bradley S. Bender. “HIV and older adults: clinical outcomes in the era of HAART.” J Gerontol Nurs 30, no. 7 (July 2004): 16–24. https://doi.org/10.3928/0098-9134-20040701-06.
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    • Tangsinmankong, Nutthapong, Wasu Kamchaisatian, Noorbibi K. Day, John W. Sleasman, and Patricia J. Emmanuel. “Immunogenicity of 23-valent pneumococcal polysaccharide vaccine in children with human immunodeficiency virus undergoing highly active antiretroviral therapy.” Ann Allergy Asthma Immunol 92, no. 5 (May 2004): 558–64. https://doi.org/10.1016/S1081-1206(10)61764-4.
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    • Marhefka, S. L., J. J. Farley, J. R. Rodrigue, L. L. Sandrik, J. W. Sleasman, and V. J. Tepper. “Clinical assessment of medication adherence among HIV-infected children: examination of the Treatment Interview Protocol (TIP).” Aids Care 16, no. 3 (April 2004): 323–38. https://doi.org/10.1080/09540120410001665330.
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    • Tangsinmankong, Nutthapong, Wasu Kamchaisatian, Jorge Lujan-Zilbermann, Cynthia L. Brown, John W. Sleasman, and Patricia J. Emmanuel. “Varicella zoster as a manifestation of immune restoration disease in HIV-infected children.” J Allergy Clin Immunol 113, no. 4 (April 2004): 742–46. https://doi.org/10.1016/j.jaci.2004.01.768.
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    • Tuttle, Daniel L., Carter R. Coberley, Xiaoming Xie, Zhong C. Kou, John W. Sleasman, and Maureen M. Goodenow. “Effects of human immunodeficiency virus type 1 infection on CCR5 and CXCR4 coreceptor expression on CD4 T lymphocyte subsets in infants and adolescents.” Aids Res Hum Retroviruses 20, no. 3 (March 2004): 305–13. https://doi.org/10.1089/088922204322996545.
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    • Goodenow, Maureen M., Stephanie L. Rose, Daniel L. Tuttle, and John W. Sleasman. “HIV-1 fitness and macrophages.” J Leukoc Biol 74, no. 5 (November 2003): 657–66. https://doi.org/10.1189/jlb.0403186.
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    • Kohler, James J., Daniel L. Tuttle, Carter R. Coberley, John W. Sleasman, and Maureen M. Goodenow. “Human immunodeficiency virus type 1 (HIV-1) induces activation of multiple STATs in CD4+ cells of lymphocyte or monocyte/macrophage lineages.” J Leukoc Biol 73, no. 3 (March 2003): 407–16. https://doi.org/10.1189/jlb.0702358.
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    • Litherland, S. A., J. X. She, D. Schatz, K. Fuller, A. D. Hutson, R. H. Peng, Y. Li, et al. “Aberrant monocyte prostaglandin synthase 2 (PGS2) expression in type 1 diabetes before and after disease onset.” Pediatr Diabetes 4, no. 1 (March 2003): 10–18. https://doi.org/10.1034/j.1399-5448.2003.00042.x.
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    • Kou, Zhong Chen, Joshua S. Puhr, Samuel S. Wu, Maureen M. Goodenow, and John W. Sleasman. “Combination antiretroviral therapy results in a rapid increase in T cell receptor variable region beta repertoire diversity within CD45RA CD8 T cells in human immunodeficiency virus-infected children.” J Infect Dis 187, no. 3 (February 1, 2003): 385–97. https://doi.org/10.1086/367674.
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    • Sleasman, John W., and Maureen M. Goodenow. “13. HIV-1 infection.” J Allergy Clin Immunol 111, no. 2 Suppl (February 2003): S582–92. https://doi.org/10.1067/mai.2003.91.
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    • Capparelli, Edmund V., Mark Mirochnick, Wayne M. Dankner, Suzette Blanchard, Lynne Mofenson, George D. McSherry, Hannah Gay, et al. “Pharmacokinetics and tolerance of zidovudine in preterm infants.” J Pediatr 142, no. 1 (January 2003): 47–52. https://doi.org/10.1067/mpd.2003.mpd0335.
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    • Cunningham, Coleen K., Marie-Laure Chaix, Claire Rekacewicz, Paula Britto, Christine Rouzioux, Richard D. Gelber, Alejandro Dorenbaum, et al. “Development of resistance mutations in women receiving standard antiretroviral therapy who received intrapartum nevirapine to prevent perinatal human immunodeficiency virus type 1 transmission: a substudy of pediatric AIDS clinical trials group protocol 316.” J Infect Dis 186, no. 2 (July 15, 2002): 181–88. https://doi.org/10.1086/341300.
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    • Krogstad, Paul, Sophia Lee, George Johnson, Kenneth Stanley, James McNamara, John Moye, J Brooks Jackson, et al. “Nucleoside-analogue reverse-transcriptase inhibitors plus nevirapine, nelfinavir, or ritonavir for pretreated children infected with human immunodeficiency virus type 1.” Clin Infect Dis 34, no. 7 (April 1, 2002): 991–1001. https://doi.org/10.1086/338814.
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    • Aranda, Juan M., Juan C. Scornik, Sigurd J. Normann, Richard Lottenberg, Richard S. Schofield, Daniel F. Pauly, Maureen Miles, James A. Hill, John W. Sleasman, and Suzanne Skoda-Smith. “Anti-CD20 monoclonal antibody (rituximab) therapy for acute cardiac humoral rejection: a case report.” Transplantation 73, no. 6 (March 27, 2002): 907–10. https://doi.org/10.1097/00007890-200203270-00013.
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    • Tuttle, Daniel L., Cynthia B. Anders, M Janette Aquino-De Jesus, Paul P. Poole, Susanna L. Lamers, Daniel R. Briggs, Steven M. Pomeroy, et al. “Increased replication of non-syncytium-inducing HIV type 1 isolates in monocyte-derived macrophages is linked to advanced disease in infected children.” Aids Res Hum Retroviruses 18, no. 5 (March 20, 2002): 353–62. https://doi.org/10.1089/088922202753519133.
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    • Goodenow, Maureen M., Gregory Bloom, Stephanie L. Rose, Steven M. Pomeroy, Patricia O. O’Brien, Elena E. Perez, John W. Sleasman, and Ben M. Dunn. “Naturally occurring amino acid polymorphisms in human immunodeficiency virus type 1 (HIV-1) Gag p7(NC) and the C-cleavage site impact Gag-Pol processing by HIV-1 protease.” Virology 292, no. 1 (January 5, 2002): 137–49. https://doi.org/10.1006/viro.2001.1184.
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    • Gonzalez, C. E., A. Shad, M. Adde, B. U. Mueller, D. J. Venzon, N. Avila, E. S. Jaffe, et al. “A pilot study for the treatment of non-Hodgkin's lymphoma in children with acquired immunodeficiency syndromes.” International Journal of Pediatric Hematology/Oncology 7, no. 3 (October 4, 2001): 167–87.
    • Ghaffari, G., D. J. Passalacqua, B. S. Bender, D. J. Briggs, M. M. Goodenow, and J. W. Sleasman. “Human lymphocyte proliferation responses following primary immunization with rabies vaccine as neoantigen.” Clin Diagn Lab Immunol 8, no. 5 (September 2001): 880–83. https://doi.org/10.1128/CDLI.8.5.880-883.2001.
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    • Kimberlin, D. W., C. Y. Lin, R. F. Jacobs, D. A. Powell, L. Corey, W. C. Gruber, M. Rathore, et al. “Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections.” Pediatrics 108, no. 2 (August 2001): 230–38. https://doi.org/10.1542/peds.108.2.230.
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    • Kimberlin, D. W., C. Y. Lin, R. F. Jacobs, D. A. Powell, L. M. Frenkel, W. C. Gruber, M. Rathore, et al. “Natural history of neonatal herpes simplex virus infections in the acyclovir era.” Pediatrics 108, no. 2 (August 2001): 223–29. https://doi.org/10.1542/peds.108.2.223.
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    • Jankelevich, S., B. U. Mueller, C. L. Mackall, S. Smith, S. Zwerski, L. V. Wood, S. L. Zeichner, et al. “Long-term virologic and immunologic responses in human immunodeficiency virus type 1-infected children treated with indinavir, zidovudine, and lamivudine.” J Infect Dis 183, no. 7 (April 1, 2001): 1116–20. https://doi.org/10.1086/319274.
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    • Perez, E. E., S. L. Rose, B. Peyser, S. L. Lamers, B. Burkhardt, B. M. Dunn, A. D. Hutson, J. W. Sleasman, and M. M. Goodenow. “Human immunodeficiency virus type 1 protease genotype predicts immune and viral responses to combination therapy with protease inhibitors (PIs) in PI-naive patients.” J Infect Dis 183, no. 4 (February 15, 2001): 579–88. https://doi.org/10.1086/318538.
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    • Sáez-Llorens, X., R. P. Nelson, P. Emmanuel, A. Wiznia, C. Mitchell, J. A. Church, J. Sleasman, et al. “A randomized, double-blind study of triple nucleoside therapy of abacavir, lamivudine, and zidovudine versus lamivudine and zidovudine in previously treated human immunodeficiency virus type 1-infected children. The CNAA3006 Study Team.” Pediatrics 107, no. 1 (January 2001): E4. https://doi.org/10.1542/peds.107.1.e4.
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    • Briggs, D. R., D. L. Tuttle, J. W. Sleasman, and M. M. Goodenow. “Envelope V3 amino acid sequence predicts HIV-1 phenotype (co-receptor usage and tropism for macrophages).” Aids 14, no. 18 (December 22, 2000): 2937–39. https://doi.org/10.1097/00002030-200012220-00016.
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    • Kou, Z. C., J. S. Puhr, M. Rojas, W. T. McCormack, M. M. Goodenow, and J. W. Sleasman. “T-Cell receptor Vbeta repertoire CDR3 length diversity differs within CD45RA and CD45RO T-cell subsets in healthy and human immunodeficiency virus-infected children.” Clin Diagn Lab Immunol 7, no. 6 (November 2000): 953–59. https://doi.org/10.1128/CDLI.7.6.953-959.2000.
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    • Aquino-De Jesus, M. J., C. Anders, G. Miller, J. W. Sleasman, M. M. Goodenow, and W. A. Andiman. “Genetically and epidemiologically related "non-syncytium-inducing" isolates of HIV-1 display heterogeneous growth patterns in macrophages.” J Med Virol 61, no. 2 (June 2000): 171–80. https://doi.org/10.1002/(sici)1096-9071(200006)61:2<171::aid-jmv1>3.0.co;2-x.
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    • McIntosh, K., E. Cooper, J. Xu, M. Mirochnick, J. Lindsey, D. Jacobus, L. Mofenson, et al. “Toxicity and efficacy of daily vs. weekly dapsone for prevention of Pneumocystis carinii pneumonia in children infected with human immunodeficiency virus. ACTG 179 Study Team. AIDS Clinical Trials Group.” Pediatr Infect Dis J 18, no. 5 (May 1999): 432–39. https://doi.org/10.1097/00006454-199905000-00007.
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    • Sleasman, J. W., R. P. Nelson, M. M. Goodenow, D. Wilfret, A. Hutson, M. Baseler, J. Zuckerman, P. A. Pizzo, and B. U. Mueller. “Immunoreconstitution after ritonavir therapy in children with human immunodeficiency virus infection involves multiple lymphocyte lineages.” J Pediatr 134, no. 5 (May 1999): 597–606. https://doi.org/10.1016/s0022-3476(99)70247-7.
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    • Zeichner, S. L., P. Palumbo, Y. Feng, X. Xiao, D. Gee, J. Sleasman, M. Goodenow, R. Biggar, and D. Dimitrov. “Rapid telomere shortening in children.” Blood 93, no. 9 (May 1, 1999): 2824–30.
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    • Machado, L. S., J. W. Sleasman, and M. J. Ford. “Bacillus species infection of the skin as a presentation of severe combined immunodeficiency disease.” J Am Acad Dermatol 39, no. 2 Pt 1 (August 1998): 285–87. https://doi.org/10.1016/s0190-9622(98)70092-1.
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    • Mueller, B. U., J. Sleasman, R. P. Nelson, S. Smith, P. J. Deutsch, W. Ju, S. M. Steinberg, et al. “A phase I/II study of the protease inhibitor indinavir in children with HIV infection.” Pediatrics 102, no. 1 Pt 1 (July 1998): 101–9. https://doi.org/10.1542/peds.102.1.101.
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    • Tuttle, D. L., J. K. Harrison, C. Anders, J. W. Sleasman, and M. M. Goodenow. “Expression of CCR5 increases during monocyte differentiation and directly mediates macrophage susceptibility to infection by human immunodeficiency virus type 1.” J Virol 72, no. 6 (June 1998): 4962–69. https://doi.org/10.1128/JVI.72.6.4962-4969.1998.
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    • Massengill, S. F., M. M. Goodenow, and J. W. Sleasman. “SLE nephritis is associated with an oligoclonal expansion of intrarenal T cells.” Am J Kidney Dis 31, no. 3 (March 1998): 418–26. https://doi.org/10.1053/ajkd.1998.v31.pm9506678.
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    • Mueller, B. U., R. P. Nelson, J. Sleasman, J. Zuckerman, M. Heath-Chiozzi, S. M. Steinberg, F. M. Balis, et al. “A phase I/II study of the protease inhibitor ritonavir in children with human immunodeficiency virus infection.” Pediatrics 101, no. 3 Pt 1 (March 1998): 335–43. https://doi.org/10.1542/peds.101.3.335.
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    • Hampsey, J., J. Sleasman, and P. Borum. “Nutrition intervention with HIV infected children.” Faseb Journal 11, no. 3 (December 1, 1997).
    • Neu, J., J. C. Roig, W. H. Meetze, M. Veerman, C. Carter, M. Millsaps, D. Bowling, et al. “Enteral glutamine supplementation for very low birth weight infants decreases morbidity.” J Pediatr 131, no. 5 (November 1997): 691–99. https://doi.org/10.1016/s0022-3476(97)70095-7.
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    • Sleasman, J. W., B. H. Leon, L. F. Aleixo, M. Rojas, and M. M. Goodenow. “Immunomagnetic selection of purified monocyte and lymphocyte populations from peripheral blood mononuclear cells following cryopreservation.” Clin Diagn Lab Immunol 4, no. 6 (November 1997): 653–58. https://doi.org/10.1128/cdli.4.6.653-658.1997.
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    • Kontny, H. U., J. W. Sleasman, D. W. Kingma, E. S. Jaffe, N. A. Avila, P. A. Pizzo, and B. U. Mueller. “Multilocular thymic cysts in children with human immunodeficiency virus infection: clinical and pathologic aspects.” J Pediatr 131, no. 2 (August 1997): 264–70. https://doi.org/10.1016/s0022-3476(97)70164-1.
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    • Aleixo, L. F., M. M. Goodenow, and J. W. Sleasman. “Zidovudine administered to women infected with human immunodeficiency virus type 1 and to their neonates reduces pediatric infection independent of an effect on levels of maternal virus.” J Pediatr 130, no. 6 (June 1997): 906–14. https://doi.org/10.1016/s0022-3476(97)70276-2.
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    • Massengill, S. F., C. Hedrick, E. M. Ayoub, J. W. Sleasman, and K. J. Kao. “Antiphospholipid antibodies in pediatric lupus nephritis.” Am J Kidney Dis 29, no. 3 (March 1997): 355–61. https://doi.org/10.1016/s0272-6386(97)90195-5.
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    • Slayton, W., D. Anstine, F. Lakhdir, J. Sleasman, and R. Neiberger. “Tetany in a child with AIDS receiving intravenous tobramycin.” South Med J 89, no. 11 (November 1996): 1108–10. https://doi.org/10.1097/00007611-199611000-00019.
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    • Sleasman, J. W., L. F. Aleixo, A. Morton, S. Skoda-Smith, and M. M. Goodenow. “CD4+ memory T cells are the predominant population of HIV-1-infected lymphocytes in neonates and children.” Aids 10, no. 13 (November 1996): 1477–84. https://doi.org/10.1097/00002030-199611000-00004.
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    • Rasmussen, S. A., C. A. Williams, E. M. Ayoub, J. W. Sleasman, B. A. Gray, A. Bent-Williams, H. J. Stalker, and R. T. Zori. “Juvenile rheumatoid arthritis in velo-cardio-facial syndrome: coincidence or unusual complication?” Am J Med Genet 64, no. 4 (September 6, 1996): 546–50. https://doi.org/10.1002/(SICI)1096-8628(19960906)64:4<546::AID-AJMG4>3.0.CO;2-N.
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    • Lamers, S. L., J. W. Sleasman, and M. M. Goodenow. “A model for alignment of Env V1 and V2 hypervariable domains from human and simian immunodeficiency viruses.” Aids Res Hum Retroviruses 12, no. 12 (August 10, 1996): 1169–78. https://doi.org/10.1089/aid.1996.12.1169.
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    • Diaz, L. E., and J. W. Sleasman. “Factors influencing mother-child transmission of HIV-1.” Journal of the Florida Medical Association 83, no. 4 (August 6, 1996): 244–48.
    • Barrie, K. A., E. E. Perez, S. L. Lamers, W. G. Farmerie, B. M. Dunn, J. W. Sleasman, and M. M. Goodenow. “Natural variation in HIV-1 protease, Gag p7 and p6, and protease cleavage sites within gag/pol polyproteins: amino acid substitutions in the absence of protease inhibitors in mothers and children infected by human immunodeficiency virus type 1.” Virology 219, no. 2 (May 15, 1996): 407–16. https://doi.org/10.1006/viro.1996.0266.
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    • Sleasman, J. W. “The association between immunodeficiency and the development of autoimmune disease.” Adv Dent Res 10, no. 1 (April 1996): 57–61. https://doi.org/10.1177/08959374960100011101.
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    • Leon, B., M. M. Goodenow, D. J. Barrett, and J. W. Sleasman. “Congenital deficiency of CD4⁺ T lymphocytes is associated with the progressive loss of CD8⁺ T cells.” Journal of Investigative Medicine 44, no. 1 (January 1, 1996).
    • Aleixo, L. F., M. M. Goodenow, and J. W. Sleasman. “Molecular analysis of highly enriched populations of T-cell-depleted monocytes.” Clin Diagn Lab Immunol 2, no. 6 (November 1995): 733–39. https://doi.org/10.1128/cdli.2.6.733-739.1995.
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    • Tolaymat, A., F. al-Mousily, J. Sleasman, S. Paryani, and R. Neiberger. “Hyponatremia in pediatric patients with HIV-1 infection.” South Med J 88, no. 10 (October 1995): 1039–42. https://doi.org/10.1097/00007611-199510000-00008.
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    • Sleasman, J. W., T. O. Harville, G. B. White, J. F. George, D. J. Barrett, and M. M. Goodenow. “Arrested rearrangement of TCR V beta genes in thymocytes from children with X-linked severe combined immunodeficiency disease.” J Immunol 153, no. 1 (July 1, 1994): 442–48.
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    • Lamers, S. L., J. W. Sleasman, J. X. She, K. A. Barrie, S. M. Pomeroy, D. J. Barrett, and M. M. Goodenow. “Persistence of multiple maternal genotypes of human immunodeficiency virus type I in infants infected by vertical transmission.” J Clin Invest 93, no. 1 (January 1994): 380–90. https://doi.org/10.1172/JCI116970.
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    • Friedman, S. M., R. N. Mames, J. W. Sleasman, and S. M. Whitcup. “Acute retinal necrosis after chickenpox in a patient with acquired immunodeficiency syndrome.” Arch Ophthalmol 111, no. 12 (December 1993): 1607–8. https://doi.org/10.1001/archopht.1993.01090120029011.
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    • Lamers, S. L., J. W. Sleasman, J. X. She, K. A. Barrie, S. M. Pomeroy, D. J. Barrett, and M. M. Goodenow. “Independent variation and positive selection in env V1 and V2 domains within maternal-infant strains of human immunodeficiency virus type 1 in vivo.” J Virol 67, no. 7 (July 1993): 3951–60. https://doi.org/10.1128/JVI.67.7.3951-3960.1993.
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    • Sleasman, J. W., C. Hemenway, A. S. Klein, and D. J. Barrett. “Corticosteroids improve survival of children with AIDS and Pneumocystis carinii pneumonia.” Am J Dis Child 147, no. 1 (January 1993): 30–34. https://doi.org/10.1001/archpedi.1993.02160250032012.
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    • Barrett, D. J., J. W. Sleasman, D. A. Schatz, and M. Steinitz. “Human anti-pneumococcal polysaccharide antibodies are secreted by the CD5- B cell lineage.” Cell Immunol 143, no. 1 (August 1992): 66–79. https://doi.org/10.1016/0008-8749(92)90006-b.
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    • Schatz, D. A., F. Lang, A. B. Cantor, W. J. Riley, N. K. Maclaren, J. W. Sleasman, and D. J. Barrett. “CD5+ B lymphocytes in high-risk islet cell antibody-positive and newly diagnosed IDDM subjects.” Diabetes 40, no. 10 (October 1991): 1314–18. https://doi.org/10.2337/diab.40.10.1314.
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    • Sleasman, J. W., and G. B. Scott. “Pediatric HIV infection. An update.” J Fla Med Assoc 78, no. 10 (October 1991): 673–77.
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    • Sleasman, J. W., and M. M. Goodenow. “Pathogenesis and natural history of HIV infection.” J Fla Med Assoc 78, no. 10 (October 1991): 678–81.
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    • Matsuyama, T., A. Yamada, K. Deusch, J. Sleasman, J. F. Daley, Y. Torimoto, and T. Abe. “Cytochalasins enhance the proliferation of CD4 cells through the CD3-Ti antigen receptor complex or the CD2 molecule through an effect on early events of activation.” J Immunol 146, no. 11 (June 1, 1991): 3736–41.
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    • Sleasman, J. W., M. Henderson, and D. J. Barrett. “Con A-induced suppressor cell function depends on the activation of the CD4+CD45RA inducer T cell subpopulation.” Cell Immunol 133, no. 2 (April 1, 1991): 367–78. https://doi.org/10.1016/0008-8749(91)90111-n.
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    • Sleasman, J. W., C. Morimoto, S. F. Schlossman, and T. F. Tedder. “The role of functionally distinct helper T lymphocyte subpopulations in the induction of human B cell differentiation.” Eur J Immunol 20, no. 6 (June 1990): 1357–66. https://doi.org/10.1002/eji.1830200623.
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    • Sleasman, J. W., T. F. Tedder, and D. J. Barrett. “Combined immunodeficiency due to the selective absence of CD4 inducer T lymphocytes.” Clin Immunol Immunopathol 55, no. 3 (June 1990): 401–17. https://doi.org/10.1016/0090-1229(90)90127-c.
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    • McCrohan, M. B., S. W. Huang, J. W. Sleasman, P. A. Klein, and K. J. Kao. “Plasma thrombospondin as an indicator of intravascular platelet activation in patients with vasculitis.” Thromb Haemost 58, no. 3 (October 28, 1987): 850–52.
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    • Gee, A. P., C. Lee, J. W. Sleasman, M. Madden, J. Ugelstad, and D. J. Barrett. “T lymphocyte depletion of human peripheral blood and bone marrow using monoclonal antibodies and magnetic microspheres.” Bone Marrow Transplant 2, no. 2 (August 1987): 155–63.
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    • Garin, E. H., J. W. Sleasman, G. A. Richard, A. A. Iravani, and R. S. Fennell. “Pulsed methylprednisolone therapy compared to high dose prednisone in systemic lupus erythematosus nephritis.” Eur J Pediatr 145, no. 5 (October 1986): 380–83. https://doi.org/10.1007/BF00439243.
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  • Book Sections

    • Farber, D. L., J. W. Sleasman, and G. Virella. “Immune response: Antigens, lymphocytes, and accessory cells.” In Medical Immunology, Sixth Edition, 36–53, 2007.
    • Sleasman, J. W., and G. Virella. “Diagnosis of immunodeficiency diseases.” In Medical Immunology, Sixth Edition, 398–407, 2007.
    • Sleasman, J. W., and G. Virella. “Primary immunodeficiency diseases.” In Medical Immunology, Sixth Edition, 410–28, 2007.
    • Sleasman, J. W., and G. Virella. “Aids and other acquired immunodeficiency diseases.” In Medical Immunology, Sixth Edition, 430–51, 2007.

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