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Johnna M. Frierson

Assistant Professor of the Practice of Medical Education
Medical Education
203 Research Drive, Box 2604, Box 90271, Durham, NC 27708
203 Research Dr, Durham, NC 27710

Selected Publications


Utilization of Sialylated Glycans as Coreceptors Enhances the Neurovirulence of Serotype 3 Reovirus

Journal Article Journal of Virology · December 15, 2012 ABSTRACTMammalian reoviruses display serotype-specific patterns of tropism and disease in the murine central nervous system (CNS) attributable to polymorphisms in viral attachment protein σ1. While all re ... Full text Cite

The Reovirus σ1s Protein Is a Determinant of Hematogenous but Not Neural Virus Dissemination in Mice

Journal Article Journal of Virology · November 15, 2011 ABSTRACTNonstructural protein σ1s is a critical determinant of hematogenous dissemination by type 1 reoviruses, which reach the central nervous system (CNS) by a strictly blood-borne route. However, it is not known whether ... Full text Cite

Intestinal Microbiota Promote Enteric Virus Replication and Systemic Pathogenesis

Journal Article Science · October 14, 2011 Commensal microflora promote the pathogenesis of mucosally acquired viruses. ... Full text Cite