Current Appointments & Affiliations
Associate Professor in Medicine
·
2025 - Present
Medicine, Endocrinology, Metabolism, and Nutrition,
Medicine
Associate Research Professor in Pharmacology & Cancer Biology
·
2021 - Present
Pharmacology & Cancer Biology,
Basic Science Departments
Member of Duke Molecular Physiology Institute
·
2015 - Present
Duke Molecular Physiology Institute,
Institutes and Centers
Recent Publications
Acute exogenous acyl-GIP treatment enhances lipid handling and fatty acid oxidation by involving brown fat.
Journal Article EMBO Rep · November 2025 The contribution of glucose-dependent insulinotropic polypeptide receptor (GIPR) signalling in brown adipose tissue (BAT) remains underexplored. We studied the acute effects of exogenous acyl-GIP (1 nmol/kg) administration on whole-body lipid handling and ... Full text Link to item Citeα cells use both PC1/3 and PC2 to process proglucagon peptides and control insulin secretion.
Journal Article Sci Adv · September 19, 2025 α cells secrete proglucagon peptides to regulate nutrient metabolism. Recent findings support an α cell-to-β cell axis that is mediated by paracrine signaling through the glucagon receptor and glucagon-like peptide 1 (GLP-1) receptor in β cells. To address ... Full text Link to item Citeβ Cell Gαs signaling is critical for physiological and pharmacological enhancement of insulin secretion.
Journal Article J Clin Invest · August 15, 2025 The incretin peptides glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptors coordinate β cell secretion that is proportional to nutrient intake. This effect permits consistent and restricted glucose excursions across a range of ... Full text Link to item CiteRecent Grants
Regulation of Adipose Tissue Plasticity by Pericyte GIPR
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2025 - 2030Metabolic Actions of Glucagon
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2025 - 2030Endocrinology and Metabolism Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2029View All Grants
Education, Training & Certifications
York University in Toronto (Canada) ·
2010
Ph.D.