Overview
Jonathan P. Piccini, MD, MHS, FACC, FAHA, FHRS is a clinical cardiac electrophysiologist and Professor of Medicine and Population Health at Duke University Hospital and the Duke Clinical Research Institute. He is the Director of the Cardiac Electrophysiology section at the Duke Heart Center. His focus is on the care of patients with atrial fibrillation and complex arrhythmias, with particular emphasis on catheter ablation, pacing, and lead extraction. His research interests include the development and evaluation of innovative cardiovascular interventions for the treatment of heart rhythm disorders. He serves on the Board of Trustees of the Heart Rhythm Society, is an Associate Editor at JACC: Clinical Electrophysiology, and is an elected member of the American Society for Clinical Investigation. Dr. Piccini has more than 600 publications in the field of heart rhythm medicine and has been the recipient of several teaching and mentorship awards.
Current Appointments & Affiliations
Recent Publications
Antiarrhythmic drug use in atrial fibrillation among different European countries - as determined by a physician survey.
Journal Article Int J Cardiol Heart Vasc · August 2025 BACKGROUND: There is limited knowledge of physicians' antiarrhythmic drug (AAD) treatment practices for patients with atrial fibrillation and adherence to guidelines in European countries. METHODS: An online survey (n = 321) of cardiologists, cardiac elect ... Full text Link to item CiteThe Importance of Incorporating Lifestyle Modification Into AF Treatment Is Difficult to Measure
Journal Article Journal of the American College of Cardiology · July 8, 2025 Full text CiteImaging findings associated with costoclavicular intervention during lead extraction.
Journal Article Heart Rhythm · July 2025 BACKGROUND: Binding sites in the costoclavicular space are commonly encountered during transvenous lead extraction. Severe adhesions may warrant use of more aggressive rotational cutting tools or surgical intervention. It is not known whether preprocedural ... Full text Link to item CiteRecent Grants
Duke Lead Extraction Course
Inst. Training Prgm or CMEPrincipal Investigator · Awarded by Philips Image Guided Therapy Corporation · 2024 - 2027Safety and Effectiveness Evaluation of the THERMOCOOL SMARTTOUCH¿ SF Catheter with the TRUPULSE¿ Generator for treatment of drug refractory symptomatic Paroxysmal Atrial Fibrillation (PAF)
Clinical TrialPrincipal Investigator · Awarded by Biosense Webster Inc · 2024 - 2027CRD 1074 FlexPulse - Safety and effectiveness of the TactiFlex SE Catheter and Volt Pulsed Field Ablation (PFA) Generator in subjects with paroxysmal atrial fibrillation
Clinical TrialPrincipal Investigator · Awarded by St. Jude Medical Business Services Inc. · 2024 - 2026View All Grants