Joohyun Lee

Journal Article Epigenetics · December 2023 Histones are subjected to extensive covalent modifications that affect inter-nucleosomal interactions as well as alter chromatin structure and DNA accessibility. Through switching the corresponding histone modifications, the level of transcription and dive ... Full text Cite

BLZ8 activates a plastidial peroxiredoxin and a ferredoxin to protect Chlamydomonas reinhardtii against oxidative stress.

Journal Article Plant biology (Stuttgart, Germany) · October 2023 Reactive oxygen species (ROS) cause damage to various cellular processes in almost all organisms, in particular photosynthetic organisms that depend on the electron transfer chain for CO2 fixation. However, the detoxifying process to mitigate RO ... Full text Cite

Comprehensive Survey of ChIP-Seq Datasets to Identify Candidate Iron Homeostasis Genes Regulated by Chromatin Modifications.

Journal Article Methods in molecular biology (Clifton, N.J.) · January 2023 Vital biochemical reactions including photosynthesis to respiration require iron, which should be tightly regulated. Although increasing evidence reveals the importance of epigenetic regulation in gene expression and signaling, the role of histone modifica ... Full text Cite

Minireview: Chromatin-based regulation of iron homeostasis in plants.

Journal Article Frontiers in plant science · January 2022 Plants utilize delicate mechanisms to effectively respond to changes in the availability of nutrients such as iron. The responses to iron status involve controlling gene expression at multiple levels. The regulation of iron deficiency response by a network ... Full text Cite

Redundant roles of four ZIP family members in zinc homeostasis and seed development in Arabidopsis thaliana.

Journal Article The Plant journal : for cell and molecular biology · November 2021 Zinc (Zn) is essential for normal plant growth and development. The Zn-regulated transporter, iron-regulated transporter (IRT)-like protein (ZIP) family members are involved in Zn transport and cellular Zn homeostasis throughout the domains of life. In thi ... Full text Cite

PRC2-Mediated H3K27me3 Contributes to Transcriptional Regulation of FIT-Dependent Iron Deficiency Response.

Journal Article Frontiers in plant science · January 2019 Iron is an essential micronutrient for nearly all organisms, but excessive iron can lead to the formation of cytotoxic reactive oxygen species. Therefore, iron acquisition and homeostasis must be tightly regulated. Plants have evolved complex mechanisms to ... Full text Cite

Establishment of a vernalization requirement in Brachypodium distachyon requires REPRESSOR OF VERNALIZATION1.

Journal Article Proceedings of the National Academy of Sciences of the United States of America · June 2017 A requirement for vernalization, the process by which prolonged cold exposure provides competence to flower, is an important adaptation to temperate climates that ensures flowering does not occur before the onset of winter. In temperate grasses, vernalizat ... Full text Cite

Variation in shade-induced flowering in Arabidopsis thaliana results from FLOWERING LOCUS T allelic variation.

Journal Article PloS one · January 2017 Plants have evolved developmental mechanisms to ensure reproduction when in sub-optimal local environments. The shade-avoidance syndrome is one such mechanism that causes plants to elongate and accelerate flowering. Plants sense shade via the decreased red ... Full text Cite

A methyltransferase required for proper timing of the vernalization response in Arabidopsis.

Journal Article Proceedings of the National Academy of Sciences of the United States of America · February 2015 Prolonged exposure to winter cold enables flowering in many plant species through a process called vernalization. In Arabidopsis, vernalization results from the epigenetic silencing of the floral repressor flowering locus C (FLC) via a Polycomb Repressive ... Full text Cite

Two FLX family members are non-redundantly required to establish the vernalization requirement in Arabidopsis.

Journal Article Nature communications · January 2013 Studies of natural genetic variation for the vernalization requirement in Arabidopsis have revealed two genes, FRIGIDA and FLOWERING LOCUS C (FLC), that are determinants of the vernalization-requiring, winter-annual habit. In this study, we show that FLOWE ... Full text Cite

OsZIP5 is a plasma membrane zinc transporter in rice.

Journal Article Plant molecular biology · July 2010 Zinc is essential for normal plant growth and development. To understand its transport in rice, we characterized OsZIP5, which is inducible under Zn deficiency. OsZIP5 complemented the growth defect of a yeast Zn-uptake mutant, indicating that OsZIP5 is a ... Full text Cite

Zinc deficiency-inducible OsZIP8 encodes a plasma membrane-localized zinc transporter in rice.

Journal Article Molecules and cells · June 2010 Zinc is an essential micronutrient for several physiological and biochemical processes. To investigate its transport in rice, we characterized OsZIP8, a rice ZIP (Zrt, Irt-like Protein) gene that is strongly up-regulated in shoots and roots under Zn defici ... Full text Cite

Orthologs of the class A4 heat shock transcription factor HsfA4a confer cadmium tolerance in wheat and rice.

Journal Article The Plant cell · December 2009 Cadmium (Cd) is a widespread soil pollutant; thus, the underlying molecular controls of plant Cd tolerance are of substantial interest. A screen for wheat (Triticum aestivum) genes that confer Cd tolerance to a Cd hypersensitive yeast strain identified Hea ... Full text Cite

The ferroportin metal efflux proteins function in iron and cobalt homeostasis in Arabidopsis.

Journal Article The Plant cell · October 2009 Relatively little is known about how metals such as iron are effluxed from cells, a necessary step for transport from the root to the shoot. Ferroportin (FPN) is the sole iron efflux transporter identified to date in animals, and there are two closely rela ... Full text Cite

Expression of the novel wheat gene TM20 confers enhanced cadmium tolerance to bakers' yeast.

Journal Article The Journal of biological chemistry · June 2008 Cadmium causes the generation of reactive oxygen species, which in turn causes cell damage. We isolated a novel gene from a wheat root cDNA library, which conferred Cd(II)-specific tolerance when expressed in yeast (Saccharomyces cerevisiae). The gene, whi ... Full text Cite

Variation in molybdenum content across broadly distributed populations of Arabidopsis thaliana is controlled by a mitochondrial molybdenum transporter (MOT1).

Journal Article PLoS genetics · February 2008 Molybdenum (Mo) is an essential micronutrient for plants, serving as a cofactor for enzymes involved in nitrate assimilation, sulfite detoxification, abscisic acid biosynthesis, and purine degradation. Here we show that natural variation in shoot Mo conten ... Full text Cite

AtPDR12 contributes to lead resistance in Arabidopsis.

Journal Article Plant physiology · June 2005 Arabidopsis (Arabidopsis thaliana) contains about 130 ATP-binding cassette (ABC) proteins, which are likely to contribute to the transport of diverse materials, including toxic substances. However, the substrates of ABC transporters remain unknown in most ... Full text Cite

A novel family of cys-rich membrane proteins mediates cadmium resistance in Arabidopsis.

Journal Article Plant physiology · June 2004 Cadmium (Cd) is a widespread pollutant that is toxic to plant growth. However, only a few genes that contribute to Cd resistance in plants have been identified. To identify additional Cd(II) resistance genes, we screened an Arabidopsis cDNA library using a ... Full text Cite

Arabidopsis metallothioneins 2a and 3 enhance resistance to cadmium when expressed in Vicia faba guard cells.

Journal Article Plant molecular biology · April 2004 The Arabidopsis metallothionein genes AtMT1 and AtMT2 confer Cd(II) resistance to Cd(II)-sensitive yeast, but it has not been directly shown whether they or other metallothioneins provide the same protection to plants. We tested whether AtMT2a and AtMT3 ca ... Full text Cite

Functional expression of a bacterial heavy metal transporter in Arabidopsis enhances resistance to and decreases uptake of heavy metals.

Journal Article Plant physiology · October 2003 Large parts of agricultural soil are contaminated with lead (Pb) and cadmium (Cd). Although most environments are not heavily contaminated, the low levels observed nonetheless pose a high risk of heavy metal accumulation in the food chain. Therefore, appro ... Full text Cite